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A Fnac Case Of Metastatic Cystic Papillarycarcinoma Of The Thyroid Simulating Parotidtumor, Gülay Özbi̇li̇m, Müjgan Yaz, Nadir Paksoy Jan 1998

A Fnac Case Of Metastatic Cystic Papillarycarcinoma Of The Thyroid Simulating Parotidtumor, Gülay Özbi̇li̇m, Müjgan Yaz, Nadir Paksoy

Turkish Journal of Medical Sciences

No abstract provided.


A Case With Multiple Hereditary Exostosis, Ziya Bayraktaroğlu, Yavuz Coskun, Neşe Sarica, Ercan Si̇vasli Jan 1998

A Case With Multiple Hereditary Exostosis, Ziya Bayraktaroğlu, Yavuz Coskun, Neşe Sarica, Ercan Si̇vasli

Turkish Journal of Medical Sciences

No abstract provided.


Lipid Peroxidation And Lipid Metabolism Inpostmenopausal Women, Banu Önvural, Hülya Öztüre, Ata Önvural, Meral Fadiloğlu Jan 1998

Lipid Peroxidation And Lipid Metabolism Inpostmenopausal Women, Banu Önvural, Hülya Öztüre, Ata Önvural, Meral Fadiloğlu

Turkish Journal of Medical Sciences

The aims of this study were to determine the degree of lipid peroxidation in the sera of postmenopausal women and compare this with the lipid peroxidation of a premenopausal group, and to see if there was any correlation between lipid parameters and lipid peroxidation within the groups. We assayed the lipid profiles and malondialdehyde (MDA), a marker for lipid peroxidation, in a postmenopausal group (n=57, mean age=49.4±6.6), an age-matched male group (n=21, mean age=48.5±6.7) and a control group (n=31, mean age=27.7±5.2). MDA was measured as thiobarbituric acid reactive substances (TBARS) using a modified version of Yagi's method. MDA was significantly …


Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Elizabeth Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley Jan 1998

Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Elizabeth Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley

Selected Works Temporary Series

No abstract provided.


The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç Jan 1998

The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç

Turkish Journal of Medical Sciences

Vitamin E and other antioxidants prevent or minimize oxidative damage in biological systems. The level of antioxidant defense sufficient to protect the organism from high free radical concentrations is one of the new horizons for Vitamin E research. The role of Vitamin E as a protective agent aganist oxidative stress was evaluated by meas-uring the antioxidant enzyme catalase (CAT) activities in different tissues of Swiss male albino rats aged two months. In this study, rats were divided to three groups; control (n=10), E 1 (n=5) which received 25 mg/kg. per day of Vitamin E, IM. for 10 days and E …


Red Cell Membrane Protein Abnormalities Of Afamily With Hereditary Spherocytosis In Adana, Serap Yalin, Kıymet Aksoy Jan 1998

Red Cell Membrane Protein Abnormalities Of Afamily With Hereditary Spherocytosis In Adana, Serap Yalin, Kıymet Aksoy

Turkish Journal of Medical Sciences

To investigate erythrocyte membrane protein abnormalities in Çukurova region we studied a family observed to be hereditary spherocytosis. Diagnosis was made basis of clinical features. By densitometric tracing of SDS-PAGE stained by Coomassie Brillant Blue, we found two spectrin deficiency, one ankyrin deficeiency, two spectrin-band 3 deficiency, one ankyrin-band 3 deficiency and one combined spectrin-ankyrin- band 3 deficiency.


Health Professions Division Catalog Academic Year 1998-1999, Nova Southeastern University Jan 1998

Health Professions Division Catalog Academic Year 1998-1999, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Identifying Global Anatomical Differences: Deformation-Based Morphometry, J Ashburner, C Hutton, R Frackowiak, Ingrid Johnsrude, C Price, K Friston Jan 1998

Identifying Global Anatomical Differences: Deformation-Based Morphometry, J Ashburner, C Hutton, R Frackowiak, Ingrid Johnsrude, C Price, K Friston

Brain and Mind Institute Researchers' Publications

The aim of this paper is to illustrate a method for identifying macroscopic anatomical differences among the brains of different populations of subjects. The method involves spatially normalizing the structural MR images of a number of subjects so that they all conform to the same stereotactic space. Multivariate statistics are then applied to the parameters describing the estimated nonlinear deformations that ensue. To illustrate the method, we compared the gross morphometry of male and female subjects. We also assessed brain asymmetry, the effect of handedness, and interactions among these effects.


Harnessing The Human Genome Through Legislative Restraint, George P. Smith Ii Jan 1998

Harnessing The Human Genome Through Legislative Restraint, George P. Smith Ii

Scholarly Articles

The awesome predictive power of genetic medicine promises great advancements in not only the treatment of identifiable conditions but the prevention of their pathological manifestations. At the same time, the release and dissemination of this genetic or medical information poses a distinct risk of loss of privacy and stigmatization to carriers of genetic disorders. In order to safeguard the individual right of autonomy, privacy, confidentiality and informed consent-yet accommodate the legitimate interests of employers and insurers to obtain medical information relevant to their professional needs and economic responsibilities a balance must be struck legislatively at the federal and state levels …


Late Diagnosed Fanconi's Anemia Presenting Asacute Renal Failure, Hilal Mocan, M. Ziya Mocan, Alisan Yildiran Jan 1998

Late Diagnosed Fanconi's Anemia Presenting Asacute Renal Failure, Hilal Mocan, M. Ziya Mocan, Alisan Yildiran

Turkish Journal of Medical Sciences

No abstract provided.


The Effects Of Constant Darkness And Constantlight On The Pineal Gland And Thymusmorphology In The Rats, Nihal İçten, Filiz Karagöz, K. Ali Güneç Jan 1998

The Effects Of Constant Darkness And Constantlight On The Pineal Gland And Thymusmorphology In The Rats, Nihal İçten, Filiz Karagöz, K. Ali Güneç

Turkish Journal of Medical Sciences

It is known that periods of constant darkness and constant light cause stim-ulation and inhibition of melatonin secretion from the pineal gland. It is also suggested that neuroendocrine responses to environmental stimuli, such as light, can influence immune responses through the pineal gland. For these reasons, in this study the effects of the alterations in the photoperiod rhythm on the pineal gland and thymus morphology were experimentally investigated. 30 Swiss albino rats, aged 4 wk, were divided into 3 groups. Group I rats were kept in a dark room, group II in a room under a bright artificial light and …


The Effects Of Vitamin E On Gastric Ulcers Andgastric Mucosal Barrier In Stress Induced Rats, Cihat Güzel, Doğan Kurt, Abdurrahman Sermet, Zeki Kanay, Orhan Denli̇, Fikri Canoruç Jan 1998

The Effects Of Vitamin E On Gastric Ulcers Andgastric Mucosal Barrier In Stress Induced Rats, Cihat Güzel, Doğan Kurt, Abdurrahman Sermet, Zeki Kanay, Orhan Denli̇, Fikri Canoruç

Turkish Journal of Medical Sciences

Effects of vitamin E on gastric ulcers gastric mucosal barrier were in-vestigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stress treated rats significantly decreased mucus and phospholipid content of gastric mucosa (p


Cyclospora Sp. Associated With Diarrhea In Apatient With Aids In Turkey, A. Nedret Koç, Bilge Aygen, İzzet Şahi̇n, Üner Kayabaş Jan 1998

Cyclospora Sp. Associated With Diarrhea In Apatient With Aids In Turkey, A. Nedret Koç, Bilge Aygen, İzzet Şahi̇n, Üner Kayabaş

Turkish Journal of Medical Sciences

No abstract provided.


Significance Of The Kccl Cytoplasmic Cooh-Terminal Fragment For The Ph Dependence Of K-Cl Cotransport In Transfected Human Embryonic Kidney Cells, Norma C. Adragna, Jin Zhang, Peter K. Lauf Jan 1998

Significance Of The Kccl Cytoplasmic Cooh-Terminal Fragment For The Ph Dependence Of K-Cl Cotransport In Transfected Human Embryonic Kidney Cells, Norma C. Adragna, Jin Zhang, Peter K. Lauf

Pharmacology and Toxicology Faculty Publications

No abstract provided.


Hüseyin Eray Bulut,Erdoğan Gürsoy, An Ultrastructural Study Jan 1998

Hüseyin Eray Bulut,Erdoğan Gürsoy, An Ultrastructural Study

Turkish Journal of Medical Sciences

Cryptorchidism causes a failure in testosterone secretion from the testicles. The metabolism of the adrenocortical steroids is influenced by sex hormones. Therefore testicular failure may cause structural and func-tional alterations in adrenal cortex. It is the aim of the present study to evaluate the effect of experimental caryptorchidism on the ultrastructure of the rat adrenal cortex, especialy on the reticularis region during prepubertal and postpubertal ages. Three groups of animals were used in the present study. The first (prepubertal) group consisted of 5,21-day old rats whereas the second (postpubertal) group was made of 5,3-month old rats. Third group was the …


Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü Jan 1998

Identification Of Fibronectin Adhesins On Candidaalbicans, Gülhan Vardar-Ünlü

Turkish Journal of Medical Sciences

The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.


Traumatic Distruption Of A Gastrojejunalanastomosis, Mahmut Başoğlu, Ali Kiliç, Talip Basak, Ali Güneş Jan 1998

Traumatic Distruption Of A Gastrojejunalanastomosis, Mahmut Başoğlu, Ali Kiliç, Talip Basak, Ali Güneş

Turkish Journal of Medical Sciences

No abstract provided.


The Change Of Glutathione Dependentanti-Oxidant Mechanism In Patients With Chronicrenal Disease By Hemodialysis, Hatice Paşaoğlu, Sabahattin Muhtaroğlu, Mehmet Güneş, Cengiz Utaş Jan 1998

The Change Of Glutathione Dependentanti-Oxidant Mechanism In Patients With Chronicrenal Disease By Hemodialysis, Hatice Paşaoğlu, Sabahattin Muhtaroğlu, Mehmet Güneş, Cengiz Utaş

Turkish Journal of Medical Sciences

In order to test the for existence of a possible effect during hemodialysis we investigated glutathione and related enzymes before and after dialysis of 36 patients (20 M/16 F) with chronic renal failure (CRF). 25 healthy person (15 M/10F) served as controls. Erythrocyte reduced glutathione (GSH) concentrations, glucose -6- phosphate dehydrogenase (G-6-PD), glutathione peroxidase (GPX) activities and plasma GPX activities were significantly decreased in patients (p


Sensory Conduction Along The Fourth Finger Inpatients With Carpal Tunnel Syndrome, H. Özden Şener, Nezih Yücemen, Nermin Mutluer Jan 1998

Sensory Conduction Along The Fourth Finger Inpatients With Carpal Tunnel Syndrome, H. Özden Şener, Nezih Yücemen, Nermin Mutluer

Turkish Journal of Medical Sciences

The aim of this study was to examine the value of sensory conduction along the median and ulnar nerves of the fourth finger in the diagnosis of carpal tunnel syndrome. 20 females with carpal tunnel syndrome as diagnosed by clinical and routine electrophysiological examinations were included in the study. By using the near-nerve technique, orthodromic sensory conduction along the thumb, 3rd, and 4th fingers for median; and 4th and 5th fingers for ulnar nerve study was performed. 't test' was used for statistical analysis In 19 of 20 patients with carpal tunnel syndrome, the conduction velcocity was reduced along the …


Prevalence Of Rheumatoid Factor (Rf) Andanti-Native-Dna Antibodies (Anti-N Dna) Indifferent Age Subpopulations, Fatoş Önen, Cansel Türkay, Ali Meydan, H. Sebila Dökmetaş, Haldun Sümer, Lütfi Hocaoğlu, Serhat Içagasioğlu, M. Zahir Bakici Jan 1998

Prevalence Of Rheumatoid Factor (Rf) Andanti-Native-Dna Antibodies (Anti-N Dna) Indifferent Age Subpopulations, Fatoş Önen, Cansel Türkay, Ali Meydan, H. Sebila Dökmetaş, Haldun Sümer, Lütfi Hocaoğlu, Serhat Içagasioğlu, M. Zahir Bakici

Turkish Journal of Medical Sciences

In this study, we have evaluated the prevalence of RF and anti-n-DNA in dif-ferent age subpopulations grouped according to their clinical status. RF and anti-n-DNA were measured in the serum of 51 elderly people considered to be successfully aging (group 1), 65 chronically ill elderly (group 2), 65 chronically ill patients under 65 years (group 3) and 30 patients with rheumatoid arthritis (group 4). The results were compared to 100 healthy persons as a control group under 65 years. The prevalences of RF in group 1, group 2 and group 3 were significantly higher than the healthy younger controls. Particularly …


Value Of Anti-Kp 90 Lmmunoglobulin A (Lga)Antibodies In Diagnosis Of Active Tuberculosis: Apreliminary Report, Sevtap Arikan, Serdar Tuncer, Dürdal Us, Serhat Ünal, Şemsettin Ustaçelebi̇ Jan 1998

Value Of Anti-Kp 90 Lmmunoglobulin A (Lga)Antibodies In Diagnosis Of Active Tuberculosis: Apreliminary Report, Sevtap Arikan, Serdar Tuncer, Dürdal Us, Serhat Ünal, Şemsettin Ustaçelebi̇

Turkish Journal of Medical Sciences

The lack of a rapid and reliable method for diagnosis of active tuberculosis necessitated the development of new laboratory techniques. Diagnostic value of a re-cently developed ELISA for the detection of lgA antibodies to Kp 90 antigen of Mycobacterium tuberculosis was evaluated in this study and the results were compared with the conventional methods and polymerase chain reaction (PCR). Fifty six sera and body fluid (pleural, peritoneal, pericardial) samples from 23 patients with ac-tive tuberculosis and 26 control subjects were included in the study. Out of 28 samples obtained from the patients, 22 (79%) yielded positive result for lgA. Comparison …


A Case Of Trisomy 8 Mosaicism, Sadık Akşi̇t, Meral Türker, Işın Yaprak, Suat Çağlayan, Coskun Dorak, Savaş Kansoy Jan 1998

A Case Of Trisomy 8 Mosaicism, Sadık Akşi̇t, Meral Türker, Işın Yaprak, Suat Çağlayan, Coskun Dorak, Savaş Kansoy

Turkish Journal of Medical Sciences

No abstract provided.


Blood And Fingernail Copper (Cu) Andmagnesium (Mg) Levels Of Children With Acutelymphoblastic Leukemia, İdris Akkuş, Mehmet Gürbi̇lek, Ümran Çalişkan, Bünyamin Kaptanoğlu, Abdurrahman Üner Jan 1998

Blood And Fingernail Copper (Cu) Andmagnesium (Mg) Levels Of Children With Acutelymphoblastic Leukemia, İdris Akkuş, Mehmet Gürbi̇lek, Ümran Çalişkan, Bünyamin Kaptanoğlu, Abdurrahman Üner

Turkish Journal of Medical Sciences

In this study, serum and fingernali Cu and Mg levels of 10 children with acute Iymphoblastic leukemia and 12 healthy children were determined. Copper and magnesium levels of the sera and supernatants were measured by atomic absorption spectrophotometer. (Perkin-Elmer 400). Fingernail Cu and Mg levels of the patients were 8.67 ± 5.35 and 0.22 ± 0.12 µmol/mg of nail respectively. The values for control subjects were 4.27 ± 2.32 and 0.14 ± 0.03 µmol/mg of nail. Serum Cu and Mg levels of the patients were 525.1 ± 160.9 µg/dl and 2.42 ± 0.54 mg/dl, and those of controls were 115.0 …


The Importance Of Creatine Phosphokinase (Cpk) And Lactate Dehydrogenase (Ldh) In The Earlydiagnosis Of Testicular Torsion, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Sabahattin Aydin, Selim Topal, Öner Odabas, Yüksel Yilmaz, Mehmet Kara Jan 1998

The Importance Of Creatine Phosphokinase (Cpk) And Lactate Dehydrogenase (Ldh) In The Earlydiagnosis Of Testicular Torsion, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Sabahattin Aydin, Selim Topal, Öner Odabas, Yüksel Yilmaz, Mehmet Kara

Turkish Journal of Medical Sciences

We aimed to reveal the value of serum CPK and LDH levels in he early diagnosis of testicular tortion in this study. 15 adult male New Zealand rabbits were divided into 2 groups. The first group included 7 animals that experienced sham operation and approved as control animals. In the second group (n=8), the left testes were just twisted 720 degrees and fixed by a transmesorchial suture like Ryan described. Blood samples were obtained by venapuncture at 0, 4, 8, 24 hours and 4 weeks in each group; creatine phosphokinase (CPK) and lactate de-hydrogenase (LDH) were determined. There was slight …


In Vivo And In Vitro Nuclear Magnetic Resonance Imaging And Spectroscopy Of Psychoactive Drugs In Rat Brain, Diana M. Lindquist Jan 1998

In Vivo And In Vitro Nuclear Magnetic Resonance Imaging And Spectroscopy Of Psychoactive Drugs In Rat Brain, Diana M. Lindquist

Theses and Dissertations

Four psychoactive drugs were studied using various in vivo nuclear magnetic resonance (NMR) techniques. Trifluoperazine (TFP) was given to several normal rats, whose brains were then studied using in vivo fluorine-19 NMR. Three peaks were detected in the in vivo fluorine spectra: one at -62 ppm, which was due to TFP, and two others at -55 and -75 ppm, which are due to unknown metabolites of TFP. Samples of skin, skull, muscle, and brain were obtained from these rats and extracted for in vitro analysis. The metabolites responsible for the in vivo peak at -75 ppm also appeared in the …


Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal Jan 1998

Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal

Turkish Journal of Medical Sciences

Urinary N-acetyl-\beta-D-glucosaminidase (NAG) levels of twenty healthy full-term newborns and of seventeen full-term newborns with perinatal asphyxia were evaluated within the first 48 hours of life. Urinary NAG levels and NAG indices (urinary NAG/urinary creatinine ratio) were sig-nificantly higher in newborns with perinatal asphyxia than control group (p


Providencia Ssp In Nosocomial Urinary Infections, Efsun Akbaş, Orhan Cem Aktepe, Belkıs Levent, İbrahim Dalkilinç, Engin Güvener Jan 1998

Providencia Ssp In Nosocomial Urinary Infections, Efsun Akbaş, Orhan Cem Aktepe, Belkıs Levent, İbrahim Dalkilinç, Engin Güvener

Turkish Journal of Medical Sciences

This study was carried out in the Ankara Rehabilitation Centre over an eight month period. A total of 428 urine samples was collected from inpatients with long-term catheterization for diagnosis of bacteriuria. Urinary tract infection was detected in three hundreds and thirty-one samples. Escherichia coli was found to be the highest causative agent. Moreover in forty of these samples Providencia spp were determined as the fifth highest causative agent. This Providencia spp finding is important as it is the highest recorded in Turkey. Although six out of 40 isolates were during preservation, the remaining thirty-four isolates were further investigated to …


Age-Related Alterations In Superoxide Dismutaseand Catalase Activities In Rat Brain, Gülinnaz Alper, Eser Y. Sözmen, Lütfiye Kanit, Gülriz Mentes, Biltan Ersöz, Fatma Z. Kutay Jan 1998

Age-Related Alterations In Superoxide Dismutaseand Catalase Activities In Rat Brain, Gülinnaz Alper, Eser Y. Sözmen, Lütfiye Kanit, Gülriz Mentes, Biltan Ersöz, Fatma Z. Kutay

Turkish Journal of Medical Sciences

Active oxygen species have been proposed to be involved in the aging process of the brain, therefore alterations in the activities of enzymes involved in the defense system against free radicals and other active species could substantially influence the aging process. This study is planned to determine the brain superoxide dismutase (SOD) and catalase activities which defend the components of brain cells against active oxygen species, in order to evaluate whether they play a role in the aging process. The activities of SOD and catalase were measured in the cerebral cortex and cerebellum of Swiss male albino rats aged either …


The Measurement Of Sweat Intensity Using Anew Technique, M. Tunaya Kalkan, Ertugrul H. Aydemi̇r, Yunus Karakoç, M. Ali Körpinar Jan 1998

The Measurement Of Sweat Intensity Using Anew Technique, M. Tunaya Kalkan, Ertugrul H. Aydemi̇r, Yunus Karakoç, M. Ali Körpinar

Turkish Journal of Medical Sciences

In this study, a new technique developed by us, called the "pad glove method" was used to measure sweat intensity in the palms of 15 patients with palmoplantar hyperhidrosis, and of 15 control subjects. Quantitative results in the hyperhidrosis group 2.1861±0.0836 grams/hour for the right hand and 2.2478±0.0961 grams/hour for the left hand, while in the control group were 0.3278±0.0419 grams/hour and 0.371±0.0501 grams/hours, respectively. Data were analyzed by Student's t test. The sweat intensities in the hyperhidrosis group were found to be significantly higher than in the control group in both hands (p


Bone Marrow Involment And Myelofibrosis In Hudgkin's Disase, Sare Kabukçuoğlu, Ülkü Öner, Zeki Üstüner, Serap Işiksoy, Emine Dündar, Nilüfer Tel Jan 1998

Bone Marrow Involment And Myelofibrosis In Hudgkin's Disase, Sare Kabukçuoğlu, Ülkü Öner, Zeki Üstüner, Serap Işiksoy, Emine Dündar, Nilüfer Tel

Turkish Journal of Medical Sciences

The importance of bone marrow biopsy in Hudgkin's Disase is well known. The incidence of bone marrow involvement in Hudgkin's Disase varies from 2% to 29%. The presence of myelofibrosis is not sufficent evidence for a definitive diagnosis of bone marrow involment. Patients having myelofibrosis as a first symptom without pripherallympadenopathy must be distinguished from patients with idiopathic myelofibrosis. In this study, we examined the frequency of bone marrow involvement and the degree of myelofibrosis in Hudgkin's Disase. We found the incidence of bone marrow involvement to be 5.6%, and that of myelofibrosis to be 31.6%. The high incidence of …