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Serum Carnitine Levels In Patients With Coronaryartery Disease, Serkan Özgi̇rgi̇n, Di̇lek Özmen, Işil Mutaf, Nevbahar Turgan, Hakan Kültürsay, Oya Bayindir, Necla Ni̇şli̇ Jan 2000

Serum Carnitine Levels In Patients With Coronaryartery Disease, Serkan Özgi̇rgi̇n, Di̇lek Özmen, Işil Mutaf, Nevbahar Turgan, Hakan Kültürsay, Oya Bayindir, Necla Ni̇şli̇

Turkish Journal of Medical Sciences

Carnitine is an essential molecule for the transfer of long chain fatty acids through the inner mitochondrial membrane, for beta-oxidation (1). The long chain fatty acids provide a large proportion of the energy requirement of the myocardium. Thus, adequate amounts of tissue carnitine are required to maintain the normal function of the myocardium (2). Experimental studies on acute myocardial ischemia and clinical investigations of patients with congestive cardiac failure have indicated that the myocardial carnitine content was significantly lowered in both conditions, in contrast to raised or normal blood carnitine (3-5). In the present study, alterations in serum carnitine levels …


Alprazolam And Cognitive Behavior Therapy Intreatment Of Panic Disorder, Ahmet Ataoğlu, Mustafa Özkan, Hamdi̇ Tutkun, Abdullah Maraş Jan 2000

Alprazolam And Cognitive Behavior Therapy Intreatment Of Panic Disorder, Ahmet Ataoğlu, Mustafa Özkan, Hamdi̇ Tutkun, Abdullah Maraş

Turkish Journal of Medical Sciences

Panic is an often incapacitating and chronic disorder. Cognitive behaviour therapy (CBT) and alprazolam have been shown to be effective in the treatment of panic disorder. Patients who met the DSM-III-R criteria for panic disorder, were randomized and given 16 weeks of double-blind treatment with CBT (n=16), or alprazolam of up to 6 mg/day (n=18). The 17-item HAM-D and HAM-A scales were administered to all the subjects before and after treatment, which took place over 16 weeks, and the changes in the scores were analyzed. The patients' anxiety levels and numbers of panic attacks were assessed at the beginning of …


Determining Functional Hand Capacity In Textileworkers In Different Departments, Hani̇fegül Taşkiran, Ali̇ Ki̇ti̇ş, Hülya Akdur Jan 2000

Determining Functional Hand Capacity In Textileworkers In Different Departments, Hani̇fegül Taşkiran, Ali̇ Ki̇ti̇ş, Hülya Akdur

Turkish Journal of Medical Sciences

The aim of this study, which was carried out in the Textile Department of the Denizli Printing and Dyeing Industry Inc., was to compare ergonomic work analysis findings in which the functional hand capacity of workers and working conditions were evaluated. A total of 225 textile workers (143 women and 82 men) were included in our study. The working conditions were evaluated by ergonomic work analysis. The functional hand capacities of the workers were evaluated by the Valpar Upper Extremity Range of Motion Test and the Purdue Pegboard Test. The results that were obtained were interpreted by the statistical methods …


Prevalence Of Diabetes Mellitus And Affectedfactors In The District Of Kayseri Health Grouparea, Yusuf Öztürk, Mualla Aykut, Fahretti̇n Keleşti̇mur, Osman Günay, Fevzi̇ye Çeti̇nkaya, Osman Ceyhan, Mücahi̇t Eğri̇ Jan 2000

Prevalence Of Diabetes Mellitus And Affectedfactors In The District Of Kayseri Health Grouparea, Yusuf Öztürk, Mualla Aykut, Fahretti̇n Keleşti̇mur, Osman Günay, Fevzi̇ye Çeti̇nkaya, Osman Ceyhan, Mücahi̇t Eğri̇

Turkish Journal of Medical Sciences

The aim of this study was to determine the prevalence of diabetes mellitus and associated risk factors in rural Kayseri in Central Anatolia and to demonstrate whether glucometers can be used in epidemiological studies. This research was performed in Kayseri in 1994. The research population consisted of 3713 people chosen randomly among men and women of 30 years of age and over. The prevalence of diabetes mellitus was identified as 5.6 %. In addition, the prevalence of diabetes mellitus was found to be higher in men than in women, in people of 50 and over than in people of 49 …


Adult Respiratory Distress Syndrome Caused By Psittacosis, Aysun Yilmazlar, Beri̇n Özcan, Nuray Kaplan, Oya Kutlay Jan 2000

Adult Respiratory Distress Syndrome Caused By Psittacosis, Aysun Yilmazlar, Beri̇n Özcan, Nuray Kaplan, Oya Kutlay

Turkish Journal of Medical Sciences

No abstract provided.


Effect Of Low-Intensity Microwave Radiation On Rat Kidney: An Ultrastructural Study, Yusuf Nergi̇z, M. Aydin Ketani̇, Zülküf Akdağ, Ahmet Reşi̇t Ersay, M. Sali̇h Çeli̇k Jan 2000

Effect Of Low-Intensity Microwave Radiation On Rat Kidney: An Ultrastructural Study, Yusuf Nergi̇z, M. Aydin Ketani̇, Zülküf Akdağ, Ahmet Reşi̇t Ersay, M. Sali̇h Çeli̇k

Turkish Journal of Medical Sciences

Exposure to low-intensity microwave radiation for prolonged periods is known to be a potential factor inducing visceral damage. There are several studies in the literature demonstrating the harmful effects of such radiation on the kidney of laboratory animals. Our aim was to determine the effect of low intensity microwave radiation on rat kidney at the light and electron microscopic level. Animals (28 rats) in the experiment group were exposed to 2.65 mW/cm 2 radition (9450 MHz) for 1 h per day during 26 and 52 days respectively and tissue samples of these animals were examined and compared with those of …


Lymphocyte Subsets In Acute Post-Streptococcal Glomerulonephritis, Yavuz Tekeli̇oğlu, Hi̇lal Mocan, M. Zi̇ya Mocan, H. Önder Ersöz Jan 2000

Lymphocyte Subsets In Acute Post-Streptococcal Glomerulonephritis, Yavuz Tekeli̇oğlu, Hi̇lal Mocan, M. Zi̇ya Mocan, H. Önder Ersöz

Turkish Journal of Medical Sciences

This prospective study was designed to investigate lymphocyte subsets in acute post-streptococcal glomerulonephritis (APSGN). Peripheral blood lymphocytes were analyzed using fluorescein isothiocyanate (FITC) labeled CD3, CD4, CD8, CD14, CD19, CD45, CD56, CD45RA and CDW29 monoclonal antibodies by flow cytometry. Twenty patients aged 14-22 years who fulfilled the diagnostic criteria for APSGN were evaluated during the 1st and 12th weeks of the of disease. Twenty-four age-matched healthy subjects served as controls. At the onset of the disease, all patients had macroscopic haematuria with red blood cell casts in urine, proteinuria (1.06±0.21 g/d), low complement 3 (C3) levels (200 IU/ml), edema, oliguria …


Biodegradable Implants In Orthopaedics And Traumatology, Haluk Yetki̇n, Alpaslan Şenköylü, Erdal Ci̇la, Aki̇f Muhtar Öztürk, Sezai̇ Aykin Şi̇mşek Jan 2000

Biodegradable Implants In Orthopaedics And Traumatology, Haluk Yetki̇n, Alpaslan Şenköylü, Erdal Ci̇la, Aki̇f Muhtar Öztürk, Sezai̇ Aykin Şi̇mşek

Turkish Journal of Medical Sciences

Biodegradable implants are an alternative to metallic implants and have the advantage of not being necessary to remove once the fracture has healed. Twenty-two patients with fractures were treated with biodegradable implants. There were osteolysis in eleven patients; however, no serious complication was encountered. Although biodegradable implants are expensive, a second surgical procedure to remove the implants is not necessary, relieving the patient of the related costs and risks.


Klippel-Trenaunay Syndrome, Pinar Polat, Beşi̇r Erdoğmuş, Suat Eren, Selami̇ Suma, Abdul Meci̇t Kantarci Jan 2000

Klippel-Trenaunay Syndrome, Pinar Polat, Beşi̇r Erdoğmuş, Suat Eren, Selami̇ Suma, Abdul Meci̇t Kantarci

Turkish Journal of Medical Sciences

No abstract provided.


Congenital Chylothorax, Ni̇lgün Köksal, Sultan Demi̇r, Mehmet Okan, Cengi̇z Gebi̇teki̇n, Işik Şenkaya Jan 2000

Congenital Chylothorax, Ni̇lgün Köksal, Sultan Demi̇r, Mehmet Okan, Cengi̇z Gebi̇teki̇n, Işik Şenkaya

Turkish Journal of Medical Sciences

No abstract provided.


A Comparative Analysis Of Perinatal Development Of Barrel Cortex In Rat, Mouse And Guinea Pig Using Acetylcholinesterase Histochemistry, Erdoğan Şendemi̇r Jan 2000

A Comparative Analysis Of Perinatal Development Of Barrel Cortex In Rat, Mouse And Guinea Pig Using Acetylcholinesterase Histochemistry, Erdoğan Şendemi̇r

Turkish Journal of Medical Sciences

The role of acetylcholinesterase (AChE) in the developing neocortex was reexamined by comparing its expression in rats, mice and guinea pigs, following the protocol for acetylcholinesterase histochemistry (described in Sendemir et al., 1996) in order to determine the suitability of the breeding colony at UludaÛ University for use as an animal model. A total of 103 pups as well as two adult animals of each species were used. In the rat pups, acetylcholinesterase-rich patches were distributed in a vibrissa-related array in the somatosensory cortex soon after birth, whereas regions of the cortex lying between individual patches and between rows of …


Effect Of Melatonin On Hepatic Fibrogenesis, Vitamin C And Hydroxyproline Levels In Liver Of Ethanol-Fed Rats, Bi̇lal Üstündağ, Nadi̇re Çi̇nkilinç, İhsan Hali̇feoğlu, Hali̇t Canatan, İbrahi̇m Hani̇fi̇ Özercan Jan 2000

Effect Of Melatonin On Hepatic Fibrogenesis, Vitamin C And Hydroxyproline Levels In Liver Of Ethanol-Fed Rats, Bi̇lal Üstündağ, Nadi̇re Çi̇nkilinç, İhsan Hali̇feoğlu, Hali̇t Canatan, İbrahi̇m Hani̇fi̇ Özercan

Turkish Journal of Medical Sciences

Pineal-gland-derived melatonin (N- Acetyl 5-Methoxytryptamine), which is a known antioxidant hormone, is known to have inhibitory effects on cell growth and proliferation. Ethanol causes increases in lipid peroxidation, superoxide formation and collagen synthesis resulting in fibrosis in the liver due to alcohol intake. The aim of this study was to examine the effect of exogenously administered melatonin on liver tissue damage resulting from alcohol intake. A total of 30 male wistar albino rats were divided into three groups; Group 1 (control), Group 2 (ethanol-administration), and Group 3 (ethanol +melatonin administration). All the rats were fed with a specially modified diet …


Alterations Of Muc2 Mucin In Colorectal Adenocarcinoma, Nurten Aksoy, Anthony P. Corfield, Christos Paraskeva, David J. Thornton, John K. Sheehan Jan 2000

Alterations Of Muc2 Mucin In Colorectal Adenocarcinoma, Nurten Aksoy, Anthony P. Corfield, Christos Paraskeva, David J. Thornton, John K. Sheehan

Turkish Journal of Medical Sciences

MUC2 is a well-identified intestinal mucin, present predominantly in the small intestine and colon. It is known that pathological alterations in the expression and composition of this mucin occur in several serious diseases related to epithelial surfaces, e.g., carcinoma and colitis ulcerosa. In this study, our aim was to find out whether there are any specific alterations in the expression and secretion of MUC2 in an adenoma- adenocarcinoma sequence that has been established as an in vitro model (1,2). The adenoma-carcinoma sequence represents the first example of the malignant progression of human colonic adenoma cells in vitro (2,3). Using a …


Analysis Of Methicillin Resistant Staphylococcus Aureus Isolates By Polyacrylamide Gel Electrophoresis In An Intensive Care Unit Of Übni-Sina Hospital, Sefa Can Saçilik, Özlem Osmanağaoğlu, İffet Palabiyikoğlu, J. Sedef Bengi̇sun, Cumhur Çökmüş Jan 2000

Analysis Of Methicillin Resistant Staphylococcus Aureus Isolates By Polyacrylamide Gel Electrophoresis In An Intensive Care Unit Of Übni-Sina Hospital, Sefa Can Saçilik, Özlem Osmanağaoğlu, İffet Palabiyikoğlu, J. Sedef Bengi̇sun, Cumhur Çökmüş

Turkish Journal of Medical Sciences

This study was designed in order to evaluate the relationship of MRSA isolates obtained from an intensive care unit (ICU) and other wards as well as the epidemiological features and typing methods. Two polyacrylamide gel electrophoretic methods of typing MRSA isolates-sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS- PAGE) and native-PAGE (N-PAGE) were evaluated and their antibiotic susceptibility patterns were determined. MRSA isolates were investigated according to the whole cell proteins (WCPs) and filtrate proteins (FPs). No report has been published yet explaining the characterization of staphylococci in SDS-PAGE by use of filtrate protein profiles. One clonal group was identified by …


Determination Of Free Fatty Acid Composition In Plasma Membranes Of Neutrophils In Diabetics, Mevlüt Sai̇t Keleş, Yaşar Demi̇r, İrfan Altuntaş, Zuhal Umudum, Ebubeki̇r Bakan Jan 2000

Determination Of Free Fatty Acid Composition In Plasma Membranes Of Neutrophils In Diabetics, Mevlüt Sai̇t Keleş, Yaşar Demi̇r, İrfan Altuntaş, Zuhal Umudum, Ebubeki̇r Bakan

Turkish Journal of Medical Sciences

Since frequent and serious infections occur in diabetic patients, the investigation of the function of neutrophils is of importance. Any change in the lipid composition of the plasma membrane could be one of the causes of these infections. In order to investigate this possibility and to determine any abnormalities, neutrophils and monocytes were separated by the Histopaque- 1119 method from the blood samples (20 ml) of 10 diabetic and 10 healthy persons. After disruption of the cells, membrane lipids and proteins were isolated. Free fatty acids of phospholipids in membrane lipids were isolated by hydrolysing with phospholipase B under an …


A Case Of Carbamazepine-Induced Lymphocytic Interstitial Pneumonitis, Ömer Deni̇z, Ergun Tozkoparan, Ahmet İlvan, Faruk Çi̇ftçi̇, Erkan Bozkanat, Samu Öztürk Jan 2000

A Case Of Carbamazepine-Induced Lymphocytic Interstitial Pneumonitis, Ömer Deni̇z, Ergun Tozkoparan, Ahmet İlvan, Faruk Çi̇ftçi̇, Erkan Bozkanat, Samu Öztürk

Turkish Journal of Medical Sciences

No abstract provided.


The Effect Of Levonorgestrel And Melatonin Treatments On Plasma Oxidant-Antioxidant System, And Lipid/Lipoprotein Levels In Female Rats, Kader Köse, Cevad Yazici Jan 2000

The Effect Of Levonorgestrel And Melatonin Treatments On Plasma Oxidant-Antioxidant System, And Lipid/Lipoprotein Levels In Female Rats, Kader Köse, Cevad Yazici

Turkish Journal of Medical Sciences

This study was carried out in order to determine the effects of levonorgestrel (LNG) and progestin derivatives, alone and in combination with melatonin (MEL), on the plasma oxidant-antioxidant system, and also lipid and lipoprotein levels, in the rat model. Female rats were divided into 4 groups according to subcutaneous treatment with LNG (5 mg/kg/day), MEL (25 mg/kg/day) and a LNG-MEL combination (5 mg LNG/25 mg MEL/kg/day) for 5 consecutive days, and a control group. Following the treatment period, malondialdehyde (MDA), conjugated dienes (CD), thiol (SH) and glutathione peroxidase (GPx) values, as the components of the oxidant-antioxidant system, and also triglyceride …


Biological Dosimetry Following X-Ray Irradiation, Münevver Coşkun, Asli Top, Tuncay Orta Jan 2000

Biological Dosimetry Following X-Ray Irradiation, Münevver Coşkun, Asli Top, Tuncay Orta

Turkish Journal of Medical Sciences

Control radiation dose-response curves are necessary in evaluating the absorbed radiation dose of similar radiation quality following radiation accidents or in monitoring the health of both the public and radiation workers. Each biological dosimetry laboratory should establish its own control dose-response data. In this study our aim was to establish control curves for 200 kVp X-rays in our laboratory in order to estimate absorbed radiation doses following exposures. Blood samples from healthy individuals with no radiation working history were irradiated in heparinized tubes at 10 different doses 0.10-5.00 Gy. Cells from irradiated whole blood were incubated in culture containing phytohemagglutinin …


Results Of Acute Cerebral Anoxia In Adults: Is It A Reversal Sign?, Nai̇l Bulakbaşi, Yüksel Pabuşçu, H. Kemal Kurtaran, Cem Tayfun, Mustafa Taşar, Taner Üçöz Jan 2000

Results Of Acute Cerebral Anoxia In Adults: Is It A Reversal Sign?, Nai̇l Bulakbaşi, Yüksel Pabuşçu, H. Kemal Kurtaran, Cem Tayfun, Mustafa Taşar, Taner Üçöz

Turkish Journal of Medical Sciences

Objective: The aim of this study is to describe the results of acute cerebral anoxia in adults as a reversal sign. Methods: We retrospectively examined the CT and MR images of 9 patients in a vegetative state due to acute prolonged anoxia. Each of them had at least one MRI and 4 CT exams 6-12 hours, 10-14 days, 6-8 months and 1 year after the anoxic event. The degree of the cerebral atrophy and the mean density values of cerebral white matter were measured and calculated to demonstrate quantitative changes over time. Results: We detected a diffuse density decrease of …


Tepid Versus Cold Blood Cardioplegia In Patients With Low Preoperative Ejection Fraction, Rahmi̇ Zeybek, Egemen Tüzün, Tayfun Adanir, İhsan İşkesen, Mert Kestelli̇ Jan 2000

Tepid Versus Cold Blood Cardioplegia In Patients With Low Preoperative Ejection Fraction, Rahmi̇ Zeybek, Egemen Tüzün, Tayfun Adanir, İhsan İşkesen, Mert Kestelli̇

Turkish Journal of Medical Sciences

Patients undergoing aortocoronary bypass surgery were randomly assigned to receive cold (+10 ^oC, Group A, n: 36) or tepid (+29 ^oC, Group B, n: 47) blood cardioplegia. The preoperative ejection fraction of all the patients was under 40%. Cardioplegic solution was delivered in antegrade and retrograde fashion in both groups. The myocardial protective effects of these 2 different cardioplegic temperatures were compared in terms of the postoperative cardiac index and left ventricle stroke work index, dopamine and dobutamine requirements in the intensive care unit, intra aortic balloon pump requirement, intensive care unit stay length and mortality ratios. The daily mean …


Tradive Dystonia Or Tardive Myoclonus, Hatice Balaban, Muhi̇tti̇n Cenk Akbostanci, Cem Atbaşoğlu, Ali̇ Kemal Göğüş Jan 2000

Tradive Dystonia Or Tardive Myoclonus, Hatice Balaban, Muhi̇tti̇n Cenk Akbostanci, Cem Atbaşoğlu, Ali̇ Kemal Göğüş

Turkish Journal of Medical Sciences

No abstract provided.


Adsorption Of Iron Or Ferritin By Chitosan, Şi̇nasi̇ Özsoylu Jan 2000

Adsorption Of Iron Or Ferritin By Chitosan, Şi̇nasi̇ Özsoylu

Turkish Journal of Medical Sciences

No abstract provided.


Bilateral Accessory Soleus Muscle, Zeli̇ha Kurtoğlu, M. Haluk Uluutku Jan 2000

Bilateral Accessory Soleus Muscle, Zeli̇ha Kurtoğlu, M. Haluk Uluutku

Turkish Journal of Medical Sciences

No abstract provided.


Inguinal Endometriosis: A Report Of Two Cases And A Review Of The Literature, Ali̇ Kemal Uzunlar, Fahri̇ Yilmaz, Mehmet Yaldiz, Özden Kaya, Mehmet Özaydin Jan 2000

Inguinal Endometriosis: A Report Of Two Cases And A Review Of The Literature, Ali̇ Kemal Uzunlar, Fahri̇ Yilmaz, Mehmet Yaldiz, Özden Kaya, Mehmet Özaydin

Turkish Journal of Medical Sciences

No abstract provided.


Electrochemical Biosensor Based On Horseradish Peroxidase For The Determination Of Oxidizable Drugs, Arzum Erdem, Aysun Pabuccuoğlu, Burcu Meric, Kagan Kerman, Mehmet Özsöz Jan 2000

Electrochemical Biosensor Based On Horseradish Peroxidase For The Determination Of Oxidizable Drugs, Arzum Erdem, Aysun Pabuccuoğlu, Burcu Meric, Kagan Kerman, Mehmet Özsöz

Turkish Journal of Medical Sciences

An amperometric biosensor based on a carbon paste electrode modified with horseradish peroxidase (HRP) is defined as a device for the quantitative and qualitative detection of oxidizable drugs. This paper demonstrates the advantages of using HRP as the biocatalyst in the in vitro detection of oxidizable drugs in the presence of hydrogen peroxide. Amperometric analysis and batch experiments were carried out in acetate buffer (pH 4.8) in the presence of hydrogen peroxide. Amperometry was performed by applying a potential of -0.1 V (vs. Ag/AgCl), in the presence of hydrogen peroxide and adding a drug which has an oxidizable group (OxG; …


Sertoli Cell Tumor In Two Sibs With Testicular Ferminization Syndrome, İnanç Eli̇f Gürer, Ahmet Ender Demi̇rkiran, Mustafa Şare Jan 2000

Sertoli Cell Tumor In Two Sibs With Testicular Ferminization Syndrome, İnanç Eli̇f Gürer, Ahmet Ender Demi̇rkiran, Mustafa Şare

Turkish Journal of Medical Sciences

No abstract provided.


Disseminated Mycobacterium Fortuitum- Chelonae Complex Infection In A Child With Il-12 Receptor Deficiency, Sadik Akşi̇t, Deni̇z Yilmaz, Şükran Darcan, Sali̇ha Soydan, Cengi̇z Çavuşoğlu, Erol Balik, Jean Laurent Casanova, Neci̇l Kütükçüler Jan 2000

Disseminated Mycobacterium Fortuitum- Chelonae Complex Infection In A Child With Il-12 Receptor Deficiency, Sadik Akşi̇t, Deni̇z Yilmaz, Şükran Darcan, Sali̇ha Soydan, Cengi̇z Çavuşoğlu, Erol Balik, Jean Laurent Casanova, Neci̇l Kütükçüler

Turkish Journal of Medical Sciences

No abstract provided.


Colchicine Toxicity: A Patient With Pneumopericardium, Yüksel Gökel, Abdullah Canataroğlu, Sali̇m Satar, Zi̇kret Köseoğlu Jan 2000

Colchicine Toxicity: A Patient With Pneumopericardium, Yüksel Gökel, Abdullah Canataroğlu, Sali̇m Satar, Zi̇kret Köseoğlu

Turkish Journal of Medical Sciences

No abstract provided.


Cholesterol Granuloma Mass In The Middle Ear Cavity, Murat Ünal, İsmai̇l Çölhan, Yusufhan Süoğlu, Ekrem Yavuz, Tayfun Sunay Jan 2000

Cholesterol Granuloma Mass In The Middle Ear Cavity, Murat Ünal, İsmai̇l Çölhan, Yusufhan Süoğlu, Ekrem Yavuz, Tayfun Sunay

Turkish Journal of Medical Sciences

No abstract provided.


Nitric Oxide In Chronic Liver Disease, Güldal Kirkali, Semra Gezer, Nurcan Umur, Mehmet Ali̇ Özcan, Ethem Tankurt Jan 2000

Nitric Oxide In Chronic Liver Disease, Güldal Kirkali, Semra Gezer, Nurcan Umur, Mehmet Ali̇ Özcan, Ethem Tankurt

Turkish Journal of Medical Sciences

The formation of nitric oxide (NO), a free radical, increases in liver disease, where the L-arginine-nitric oxide (L- arg-NO) pathway is activated by the increased levels of cytokines and endotoxins. In this study, we investigated the relationship between the L-arg-NO pathway and chronic active hepatitis and cirrhosis, which are classified as chronic liver disease. We determined the serum levels of nitrite and nitrate, the end products of the L-arg-NO pathway, in patients with chronic liver disease and compared them with the control group levels. Total nitrite produced by the reduction of nitrate to nitrite in the presence of nitrate reductase …