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Polymorphisms In Androgen Metabolism Genes Ar, Cyp1b1, Cyp19, And Srd5a2 And Prostate Cancer Risk And Aggressiveness In Bulgarian Patients, Darina Kachakova, Atanaska Mitkova, Elenko Popov, Olga Beltcheva, Alexandrina Vlahova, Tihomir Dikov, Svetlana Christova, Vanio Mitev, Chavdar Slavov, Radka Kaneva

Turkish Journal of Medical Sciences

Background/aim: The aim of our study was to elucidate the role of polymorphisms in AR, CYP1B1, CYP19, and SRD5A2 genes for prostate cancer (PC) development in Bulgarian patients. Materials and methods: We genotyped 246 PC patients and 261 controls (155 with benign prostate hyperplasia and 107 healthy population controls) using direct sequencing, PCR-RFLP, SSCP, and fragment analysis. Results: The allele and genotype frequencies of most of the studied variants did not differ significantly between cases and controls. Increased frequencies of the C/C genotype and C allele of rs1056837 in CYP1B1, and genotype 7/8 of the (TTTA)n repeat polymorphism in CYP19, …

Telestroke: An Approach To The Shortage Of Neurologists In Rural Areas, Sarah Mcsweeney, Jean Pritt, Angie Swearingen, Alberto Coustasse

Management Faculty Research

Telestroke has provided swift, lifesaving treatment and has afforded patients the ability to be treated in an efficient manner in rural areas where neurologists may not always be available. It has been reported that Telestroke in rural areas has increased the ability to treat patients by being able to access a neurologist for assistance in evaluating the patient to determine if administering lifesaving in treatments were needed. The utilization of Telestroke has been shown to increase the use of IV Tissue Plasminogen Activator (tPA) which improves outcomes such as better quality of life, lower disability and improved rehabilitation. Employment of …

Clinical Outcomes And Optical Performance Of Four Differentmultifocal Intraocular Lenses, Başak Bostanci Ceran, Tamer Takmaz, İzzet Can, Güli̇zar Demi̇rok, Betül Seher Uysal

Turkish Journal of Medical Sciences

Background/aim: The purpose of the present study was to evaluate clinical outcomes and optical performance of 4 different multifocal intraocular lenses (IOLs). Materials and methods: Ninety eyes of 51 patients who received Reviol MFM 611, Reviol MFM 625, Acri.LISA, and ReSTOR SN6AD3 multifocal IOLs after cataract surgery were retrospectively evaluated. The patients were similar in terms of age, sex, cataract hardness and axial length. The mean outcome measures were uncorrected and corrected distance visual acuity (UDVA, CDVA), distance-corrected intermediate and near visual acuity (DCIVA, DCNVA), intra or postoperative complications, and contrast sensitivity (CS) results under mesopic conditions. The mean follow …

The Semantic Memory Imaging In Late Life Pilot Study, Michael Adam Sugarman

Wayne State University Dissertations

Introduction: Several functional magnetic resonance imaging (fMRI) studies have analyzed the famous name discrimination task (FNDT), an uncontrolled semantic memory probe requiring discrimination between famous and unfamiliar individuals. Completion of this simple task recruits a semantic memory network that has shown utility in determining risk for Alzheimer's disease (AD). Specific semantic memory probes using biographical information associated with famous individuals may build on previous findings and yield superior information regarding risk for AD.

Method: Sixteen cognitively intact elders completed the FNDT and two novel tasks during fMRI: Categories (matching famous individuals to occupational categories) and Attributes (matching famous individuals to …

Southeastern Alumni Magazine- Winter 2016, Southeastern University - Lakeland

Southeastern Alumni Magazine

Dr. Aimee Franklin '07 returned to Southeastern in 2014 as an assistant professor of biology. Prior to returning, she earned her Ph.D. in Neuroscience at the University of Alabama Birmingham where she studied Fragile X Syndrome, the leading known genetic cause for autism. One of her articles published in Biological Psychology was one of the most cited articles in that journal in 2014.

Childhood Trauma And Emotion Processing Neurocircuitry, Hilary A. Marusak

Wayne State University Dissertations

Childhood trauma is one of the strongest risk factors for a range of common and debilitating neuropsychiatric disorders, including anxiety, depression, and posttraumatic stress disorder (PTSD). These emotion-related disorders have their roots in childhood and adolescence, underscoring a critical need to understand their biological bases in early life. In this dissertation, we evaluate how childhood trauma impacts emotion processing neurocircuitry in a sample of high-risk urban youth, ages 7-15. In four inter-related studies, we test neural function and functional connectivity of core emotion processing regions, including the amygdala, insula, and pregenual/subgenual anterior cingulate cortex (pgACC/sgACC). To examine the relevance of …

Nursing Management And Mirror Therapy For Phantom Limb Pain, Bridget Henry

Honors Undergraduate Theses

Phantom limb pain may occur after the accidental removal or surgical amputation of a limb. Phantom limb pain is the experience of pain in the limb that is no longer present. The clinical management of phantom limb pain is essential in the overall reduction of patient rehabilitation and poor patient outcomes. A patient’s degree of phantom limb pain is influenced by their personal response to loss and pain and can have devastating effects to a person’s social performance, occupational role, family role, relationships, and involvement in activities or hobbies. Like most chronic pain, phantom limb pain decreases the quality of …

Vitamin D Clinical Relevance In The Recovery From Traumatic Brain Injury Among The Military Population, Yuisa M. Colón

Honors Undergraduate Theses

Background: Traumatic brain injury (TBI) still remains a difficult disorder to treat. TBI has been associated to chronic neuroinflammation and a high risk for neurodegenerative disorders. Since 2001 between ten to twenty percent of all deployed military members have suffered a combat-related TBI. Nearly twenty to thirty percent of those will experience chronic cognitive, behavioral and somatic symptoms after suffering a TBI.
Methods: The objective of this review is to evaluate current literature examining vitamin D as a neurosteroid with protective properties and its clinical relevance after traumatic brain injury. Vitamin D is known to participate in neurobiological …

Structural And Functional Characterization Of Enzymes Of A Novel Group Of Tryptophylquinone Cofactor Containing Oxidases, Esha Sehanobish

Electronic Theses and Dissertations

Protein-derived cofactors are redox and catalytic centers that are generally formed by the posttranslational modifications of one or more amino acids. An important class of these cofactors are the quinones derived from tyrosine and tryptophan. Amongst redox proteins, it has been known till now that oxidases either contain a flavin or a tyrosylquinone cofactor, whereas tryptophylquinone ones are present within the dehydrogenases. In recent times, oxidases from a marine bacterium, Marinomonas mediterranea, have been shown to possess the latter. This study involves the characterization of two such proteins, lysine-?-oxidase (LodA) and glycine oxidase (GoxA). They have been reported to contain …

Pharmacogenomic Management Of Familial Hypercholesterolemia: An Integrative Review Of The Literature, Brian V. Skibo

Honors Undergraduate Theses

The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals …

Expression Levels Of Virulence Genes In Group A Streptococci: A Response To Aerosolized Propylene Glycol, Michael S. Costello

Honors Undergraduate Theses

Electronic cigarette usage is becoming increasingly prevalent among school age children and young adults. A known bactericidal agent, propylene glycol, is often used as a carrier for nicotine, flavoring, and additional constituents of electronic cigarette juice. This study examined the relationship between propylene glycol and virulence gene expression in Streptococcus pyogenes, a respiratory tract pathogen commonly found in school-age individuals. A variety of virulence genes controlled by the three stand alone regulators mga, RofA, and Rgg/RopB were sampled in an effort to understand the pathway by which virulence is affected. The genes chosen encode C5a peptidase, fibronectin binding protein, hyaluronate …

Therapy Options For Winged Scapula Patients: A Literature Review, Samantha L. Normand

Honors Undergraduate Theses

Winged scapula is a condition characterized by lateral or medial protrusion of the scapula caused by nerve damage leading to muscular paralysis. The purpose of this systematic review of literature is to evaluate the current research literature related to the effectiveness of therapy options for winged scapula. Eleven peer reviewed English language research articles published from 1998 to present were included for evaluation. Study results revealed positive therapeutic outcomes for physical therapy and scapular bracing. Results also showed positive outcomes for the use of transcutaneous electrical nerve stimulation and acupuncture for the treatment of nerve related conditions similar to winged …

Cutaneous Human Papillomavirus Infection And Development Of Subsequent Squamous Cell Carcinoma Of The Skin, Shalaka S. Hampras, Rhianna A. Reed, Spencer Bezalel, Michael Cameron, Basil Cherpelis, Neil Fenske, Vernon K. Sondak, Jane Messina, Massimo Tommasino, Tarik Gheit, Dana E. Rollison

Pathology and Cell Biology Faculty Publications

The role of cutaneous human papillomavirus (HPV) infection in the development of subsequent cutaneous squamous cell carcinoma (SCC) is unknown. Pathologically confirmed cases of SCC () enrolled in a previously conducted case-control study were included in a retrospective cohort study to examine the association of cutaneous HPV at the time of SCC diagnosis with the risk of subsequent SCC development. Data on HPV seropositivity, HPV DNA in eyebrow hairs (EB) and SCC tumors were available from the parent study. Incidence of subsequent SCC was estimated using person-years of follow up. Cox Proportional Hazards ratios were estimated to evaluate the associations …

Assessing Cultural Competence In Nursing Students At A Small Private Liberal Arts University, Mikah K. Barrueta Ms

Undergraduate Honors Thesis Projects

Appropriate care across cultures can occur only when patient, family, and community expectations are aligned with provider knowledge, attitude, and behavior (Doorenbos et al, 2005). Because nurses treat patients from all types of backgrounds, a culturally competent approach should and must be used when educating and training future nurses. The purpose of this study is to assess various cultural competence components of senior nursing students at a small Midwestern University. In order to assess this sample population, two peer-reviewed surveys were chosen; the Quality and Culture Quiz and the Affective Racial Attitudes subscale from the Quick Discrimination Index. Three more …

Pelvic Floor Muscle Training In Management Of Postpartum Pelvic Floor Dysfunctions: A Literature Review, Rebecca S. Tanner

Honors Undergraduate Theses

Women can face a wide range of pelvic floor dysfunctions following pregnancy, ranging from urinary incontinence to pelvic pain. Unfortunately, these problems are not routinely checked for in postpartum check-ups and women do not always bring it to the physician’s attention. Strengthening of the pelvic floor muscles may be able to help women prevent these disorders and improve these women’s lifestyles.

The purpose of this thesis was to review and analyze different trials to determine if different pelvic floor dysfunctions (urinary incontinence, sexual dysfunction, and pelvic girdle pain) can be treated using pelvic floor muscle training in the postpartum. After …

Fluctuations Of State Anxiety, Spinal Structure, And Postural Stabilityacross The Menstrual Cycle In Active Women, Derya Özer Kaya, Şeyda Toprak Çelenay

Turkish Journal of Medical Sciences

Background/aim: To investigate differences in state anxiety, spinal posture and mobility, postural competency, and stability across the menstrual cycle in active women. Materials and methods: Thirteen physically active women (18?25 years) with a regular menstrual cycle were recruited. Anxiety with the Spielberger State Trait Anxiety Inventory; spinal posture, mobility, and competency with a Spinal Mouse device (Idiag, Fehraltorf, Switzerland); and postural stability with a Biodex Balance System SD (Biodex Medical Systems, Inc., Shirley, NY, USA) were evaluated across phases of the menstrual cycle. Results: No significant differences were observed between phases of the menstrual cycle for state anxiety, spinal posture, …

Study Of Mouse Induced Pluripotent Stem Cell Transplantation Intowistar Albino Rat Cochleae After Hair Cell Damage*, Mustafa Kürşat Gökcan, Selçuk Mülazi̇moğlu, Emre Ocak, Pinar Can, Murat Çalişkan, Ömer Beşalti, Serpi̇l Di̇zbay Sak, Gülşah Kaygusuz

Turkish Journal of Medical Sciences

Background/aim: As the regeneration capacity of hair cells is limited, inner ear stem cell therapies hold promise. Effects of mouse induced pluripotent stem cells (IPSCs) on Wistar albino rats (WARs) with hearing impairment were investigated. Materials and methods: Thirty-five adult WARs with normal hearing were divided into 4 groups. Excluding the study group (n = 15), the other three groups served as control groups for ototoxicity and IPSC injection models. IPSC injections were performed via cochleostomy after a retroauricular approach. Auditory functions were evaluated with auditory brainstem responses (ABRs) before and after the injections. After a final hearing assessment the …

Liporotein-Associated Phospholipase-A2 Can Be A Diagnostic Marker Inthe Early Stage Diagnosis Of Acute Mesenteric Ischemia, Tarik Acar, Sedat Koçak, Başar Cander, Mehmet Ergi̇n, Cesareddi̇n Di̇kmetaş

Turkish Journal of Medical Sciences

Background/aim: The purpose of this experimental study was to investigate the role of lipoprotein-associated phospholipase-A2 (Lp-PLA2) in the diagnosis of acute mesenteric ischemia (AMI) in the early stage. Materials and methods: Twenty-seven New Zealand rabbits were randomly divided into 3 groups in this study. Blood specimens were obtained from the groups at hours 0, 1, 3, and 6. Using the blood samples drawn from all groups, Lp-PLA2 and C-reactive protein (CRP) parameters were investigated. Results: There was a significant rise in the levels of both Lp-PLA2 and CRP starting at hour 1 (P < 0.05) (hour 1; Lp-PLA2, P = 0.003) in the ischemia group. In the sham group, the levels of Lp-PLA2 and CRP started to rise at hour 3 (P < 0.05) (hour 3; Lp-PLA2, P = 0.011). At hour 6 of ischemia, the area under the ROC curve was 100%, and the cut-off value of 63.91 ng/mL revealed a sensitivity of 88% and a specificity of 100% for Lp-PLA2. Conclusion: These findings showed the role of serum Lp-PLA2 and CRP levels in the early diagnosis of AMI. Thus, further studies are needed to describe the role of Lp-PLA2 in the early diagnosis of AMI.

Re: "Job Strain And The Cortisol Diurnal Cycle In Mesa: Accounting For Between- And Within-Day Variability, Irvin Sam Schonfeld, Renzo Bianchi

Publications and Research

Rudolph et al. (2016) examined the association between job strain and cortisol profile. Several potential confounders were considered, including sociodemographic characteristics, income-wealth index, financial strain, physical health, physical activity, and medication use. No relationship between job strain and the cortisol awakening response was observed. We have 4 comments on the methods used in the study. First, although the authors related the modifications in cortisol profiles to job strain, they did not assess and statistically control for a number of nonoccupational strain factors (e.g., family- or couple-related chronic stress). Second, depressive symptoms and disorders were not considered in the study. Depression …

Clinical Features Of Infants Treated For Severe Retinopathy Of Prematurity: 8-Yearstudy From A Large Tertiary Neonatal Intensive Care Unit In Turkey, Zühal Özen Tunay, Özdemi̇r Özdemi̇r, Damla Ergi̇ntürk Acar, İkbal Seza Petri̇çli̇, Şeri̇fe Suna Oğuz

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to report the gestational age (GA) and birth weight (BW) distribution of premature babies who needed treatment for retinopathy of prematurity (ROP) and to assess the timing of the treatment. Materials and methods: The records of 9008 infants who were screened for ROP were examined and 556 infants who underwent laser therapy for ROP were reviewed. Sex, GA, BW, postnatal age, and postmenstrual (PM) age at the time of laser therapy were recorded. The babies were classified as in-born (Group 1) and out-born infants (Group 2). Results: The mean GA was 27.3 weeks …

The Effect Of Transtheoretical Model-Based Individual Counseling, Training, And A 6-Month Follow-Up On Smoking Cessation In Adult Women: A Randomized Controlled Trial*, Ayşe Koyun, Kafi̇ye Eroğlu

Turkish Journal of Medical Sciences

Background/aim: This study was conducted to determine the effect of transtheoretical model (TTM)-based individual counseling, training, and a 6-month follow-up on smoking cessation in adult women. Materials and methods: We carried out this randomized controlled trial in Konya, Turkey. Female subjects were randomly assigned into groups in a 1:1 ratio using block randomization, block size 3 × 3, divided by stages (precontemplation, contemplation, and preparation) and age (20-29, 30-39, and 40-49 years). The study was completed with 77 women (an intervention group containing 38 participants and a control group of 39 participants). The intervention group was interviewed 5 times (baseline …

The Effect Of Proanthocyanidin On Formaldehyde-Induced Toxicity In Rat Testes, Eni̇s Uluçam, Elvan Bakar

Turkish Journal of Medical Sciences

Background/aim: This study investigated the effect of proanthocyanidin (PA) against formaldehyde (FA)-induced lipid peroxidation damage and morphological changes in rat testes. Materials and methods: Twenty-one Wistar albino rats were randomized into 3 groups: control, FA, and FA + PA groups. Plasma and tissue malondialdehyde (MDA) and total sialic acid (TSA) levels were measured. Testes tissues were observed by light and electron microscopy. Results: TSA (plasma and tissue) levels decreased and MDA (plasma) significantly increased (P < 0.05) in rats treated with FA compared to the controls. Tissue MDA levels were not significantly different. Several necrotic changes were observed in testes tissues by light and electron microscopy. Disordering in epithelia of seminiferous tubules, vacuolization between germinal epithelium cells, and separated basement membranes were observed by light microscope. Immunopositivity in Leydig cells decreased in the FA group (P < 0.05). In the FA + PA group there were more immune Leydig cells reacting immune-positively than in the FA group (P < 0.05). Ultrastructurally, FA also caused disorganization and loss of mitochondrial cristae, and dilatation in endoplasmic reticulum in testes. Conclusion: The results suggest that PA has a protective effect on FA toxicity in testes.

Evaluation Of Brainstem Auditory Evoked Potentials And Their Relationshipwith Levels Of Thyroid Autoantibodies In Patients With Vitiligo, İlhan Çeçen, Ayşe Serap Karadağ, Temel Tombul, Serap Güneş Bi̇lgi̇li̇, Ömer Çalka, Ahmet Zübeyi̇r Burakgazi̇

Turkish Journal of Medical Sciences

Background/aim: Vitiligo is a common depigmenting disorder. The damage can also occur in similar ways to melanocytes within other organs. We evaluated the brainstem and auditory pathway functions by evaluating brainstem auditory evoked potentials (BAEPs) and whether there is any relationship between auditory functions and autoimmunity. Materials and methods: Forty patients with vitiligo and 20 healthy volunteers were enrolled. Thyroid functions and autoantibodies were examined and BAEP tests were assessed by a neurologist. Results: Antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TGA) antibody positivity was higher in the patient group (P < 0.05). A negative correlation was detected between anti-TPO and lead III, IV, and V latency and I?III interpeak latency (IPL) of the right ear together with lead IV latency and I?V IPL of the left ear in the patient group. When each BAEP parameter was compared between the two groups, more abnormalities were detected in the V latency and III?V IPL of the left ear together with IV and V latency of the right ear. Conclusion: In this study the presence of a correlation between increased anti-TGA and anti-TPO levels and BAEP parameters may be related to an autoimmune-mediated mechanism. However, further studies are needed to be performed in a large patient series.

Comparison Between The Use Of Saline And Seawater For Nasal Obstruction In Children Under 2 Years Of Age With Acute Upper Respiratory Infection, Tüli̇n Köksal, Mehmet Nevzat Çi̇zmeci̇, Davut Bozkaya, Mehmet Kenan Kanburoğlu, Şanliay Şahi̇n, Tuğba Taş, Çi̇ğdem Nükhet Yüksel, Mustafa Mansur Tatli

Turkish Journal of Medical Sciences

Background/aim: The effectiveness of isotonic and hypertonic saline solutions used to open the nasal passage and improve clinical symptoms was compared in children under 2 years of age admitted with the common cold. Materials and methods: The study was performed as a randomized, prospective, and double-blind study. The study included 109 children. The children using saline (0.9%) and seawater (2.3%) as nasal drops (the patient group) and the control group (in which nasal drops were not administered) were compared. Seventy-four patients received nasal drops from package A (seawater) in single days and from package B (physiological saline) in double days. …

Macrolide And Lincosamide Resistance In Staphylococcal Clinical Isolates In Nablus, Palestine, Motasem Almasri, Nael Abu Hasan, Naela Sabbah

Turkish Journal of Medical Sciences

Background/aim: Macrolide and lincosamide antibiotics are used for the treatment of staphylococcal infections, especially for penicillin-allergic patients. In the present study, we evaluate the prevalence of resistance to macrolide and lincosamide antibiotics among staphylococci isolates. Materials and methods: A total of 200 staphylococcal clinical isolates were collected from January 2012 to April 2013. Minimal inhibitory concentrations of erythromycin and clindamycin were determined by agar dilution method. An erythromycin-clindamycin induction test was performed for isolates that were only resistant to erythromycin. Representative erythromycin-resistant isolates were examined for erythromycin resistance genes using PCR. Results: Among staphylococci isolates, resistance frequencies of erythromycin and …

Effect Of The Application Of Prophylactic Central Compartment Lymph Node Dissectionon Radioiodine Ablation Doses In Patients With Papillary Thyroid Carcinoma, Çi̇ğdem Soydal, Elgi̇n Özkan, Nuri̇ye Özlem Küçük, Kemal Meti̇n Kir

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to document the effect of the application of prophylactic central compartment dissection on radioiodine ablation activities for papillary thyroid carcinoma. Materials and methods: This retrospective study included 452 (383 females, 69 males; mean age = 46.69 years, min?max: 13?71) patients who received ablative radioiodine activity between April 2010 and December 2014. The histopathological reports of thyroidectomy and the administered radioiodine activity were evaluated. Frequencies of prophylactic central compartment dissection according to T stage of the primary tumor, detection rate of lymph node metastases, and its effect on radioiodine ablation activities were calculated. Results: …

An Analysis Of The Incidence Of Measles In Turkey Since 1960, Deni̇z Çalişkan, Bi̇rgül Pi̇yal, Recep Akdur, Mi̇ne Esi̇n Ocaktan, Ceylan Yozgatligi̇l

Turkish Journal of Medical Sciences

Background/aim: The aims of this study were to evaluate measles incidence and the effect of elimination strategy interventions on the disease from 1960 to 2014 in Turkey. The administration of measles vaccine started in the rural regions in 1970; it was carried out as a campaign along with the National Vaccine Campaign in 1985, and it has been employed as combined measles, mumps, and rubella under the scope of the Measles Elimination Program (MEP) since 2006 in Turkey. While a dramatic decrease in the reporting of measles was observed between 2000 and 2010, the number of the cases has increased …

Reliability And Validity Of The Turkish Version Of Myastheniagravis-Quality Of Life Questionnaire-15 Item, Ni̇da Fatma Taşcilar, Özge Saraçli, Mehmet Ali̇ Kurçer, Handan Ankarali, Ufuk Emre

Turkish Journal of Medical Sciences

Background/aim: The myasthenia gravis-quality of life questionnaire 15 item (MG-QOL15) is a validated, short, and easy to use disease-specific quality of life (QOL) tool in myasthenia gravis. Other than Turkish, a lot of versions of the MG-QOL15 have been used in different languages in different cultures. Therefore, the aim of this study was to translate and construct a validated and adapted Turkish version of the MG-QOL15 [MG-QOL15(T)]. Materials and methods: After translation, back-translation, and comparison of the 2 English versions of the MG-QOL15, it was tested by 22 monolingual healthy individuals and then 23 patients with clinically stable MG. Afterwards, …

The Effectiveness Of A Back School Program In Lowerlimb Amputees: A Randomized Controlled Study, Bahar Anaforoğlu, Fati̇h Erbahçeci̇, Mehmet Atif Erol Akseki̇li̇

Turkish Journal of Medical Sciences

Background/aim: A few studies have been carried out in lower limb amputees (LLAs) and they examined the incidence of and reasons for low back pain. The aim of this study was to assess the effectiveness of a back school program in LLAs with mechanical low back pain (MLBP). Materials and methods: Forty male unilateral transfemoral amputees with MLBP were randomly allocated into two groups. A back school program was applied to Group 1 over 2 weeks. A booklet for home use was given to each participant in Group 2. Pain was assessed using a visual analogue scale. Spinal flexibility measurements …

The Beneficial Effects Of Almond (Prunus Amygdalus Batsch) Hull On Serum Lipid Profile And Antioxidant Capacity In Male Rats, Soheil Safarian, Yadollah Azarmi, Ali Jahanban-Esfahlan, Hasan Jahanban-Esfahlan

Turkish Journal of Medical Sciences

Background/aim: Almond hull is produced in high amounts and mostly used as livestock feed. This study was designed to examine the impact of almond hull powder (AHP) administration on lipid profile and antioxidant activities in plasma and liver in hyperlipidemic rats. Materials and methods: As the first step, the antioxidant capacity and radical scavenging activity of AHP were determined using calorimetric methods. Then 36 adult male Wistar rats were randomly divided into 6 groups: group 1 with oral administration of 10% AHP, group 2 with oral administration of 20% AHP, group 3 with oral administration of 30% AHP, group 4 …