Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- The Texas Medical Center Library (13931)
- Thomas Jefferson University (836)
- TÜBİTAK (575)
- Chulalongkorn University (338)
- Loma Linda University (209)
-
- University of Nevada, Las Vegas (199)
- City University of New York (CUNY) (181)
- University of Central Florida (147)
- LSU Health New Orleans (101)
- University of South Florida (98)
- Saudi Medical Journal (94)
- University of South Carolina (76)
- Case Western Reserve University (58)
- University of Kentucky (54)
- Chapman University (52)
- Edith Cowan University (41)
- University of Alabama at Birmingham (35)
- Portland State University (33)
- University of Nebraska Medical Center (32)
- University of Texas Rio Grande Valley (32)
- Philadelphia College of Osteopathic Medicine (30)
- China Medical University (27)
- University of New Mexico (27)
- Neurosciences (25)
- Touro College and University System (25)
- University of Nebraska - Lincoln (24)
- Nova Southeastern University (21)
- University of Texas at Tyler (21)
- Washington University in St. Louis (21)
- University of Rhode Island (18)
- Keyword
-
- Humans (8220)
- Female (3650)
- Male (3278)
- Animals (2682)
- Mice (1790)
-
- Adult (1711)
- Middle Aged (1609)
- Aged (1269)
- Child (1231)
- Adolescent (835)
- Retrospective Studies (769)
- United States (626)
- Infant (597)
- Treatment Outcome (549)
- Young Adult (545)
- Child, Preschool (519)
- Preschool (513)
- COVID-19 (510)
- Risk Factors (504)
- Biomarkers (460)
- Tumor (456)
- Mutation (437)
- Mice, Inbred C57BL (432)
- Inbred C57BL (431)
- Animal (418)
- Neoplasms (415)
- Prospective Studies (384)
- Receptors (383)
- Brain (381)
- Disease Models, Animal (372)
- Publication Year
- Publication
-
- Faculty, Staff and Students Publications (7836)
- Faculty, Staff and Student Publications (4639)
- Turkish Journal of Medical Sciences (575)
- Children’s Nutrition Research Center Staff Publications (405)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (335)
-
- Center for Medical Ethics and Health Policy Staff Publications (286)
- Duncan NRI Faculty and Staff Publications (252)
- Loma Linda University Electronic Theses, Dissertations & Projects (206)
- The Brown Foundation: Institute of Molecular Medicine (141)
- John P. McGovern, MD Collection (136)
- Publications and Research (133)
- Department of Pathology, Anatomy, and Cell Biology Faculty Papers (130)
- UNLV Theses, Dissertations, Professional Papers, and Capstones (119)
- Department of Biochemistry and Molecular Biology Faculty Papers (118)
- Staff and Researcher Publications (100)
- Saudi Medical Journal (94)
- Theses and Dissertations (83)
- Honors Undergraduate Theses (80)
- Center on Aging Staff Publications (77)
- Department of Microbiology and Immunology Faculty Papers (73)
- Electronic Theses and Dissertations (73)
- Department of Neuroscience Faculty Papers (65)
- Faculty Scholarship (57)
- School of Medicine Faculty Publications (57)
- USF Tampa Graduate Theses and Dissertations (49)
- Department of Medicine Faculty Papers (38)
- All ETDs from UAB (35)
- Department of Cancer Biology Faculty Papers (35)
- Dissertations and Theses (Open Access) (33)
- Department of Pharmacology and Experimental Therapeutics Faculty Papers (31)
- Publication Type
- File Type
Articles 16831 - 16860 of 18071
Full-Text Articles in Entire DC Network
Association Analysis Of Five Snp Variants With Gout In The Minnan Population In China, Chenna Zheng, Huiyong Yang, Qingyao Wang, Huachun Rao, Yong Diao
Association Analysis Of Five Snp Variants With Gout In The Minnan Population In China, Chenna Zheng, Huiyong Yang, Qingyao Wang, Huachun Rao, Yong Diao
Turkish Journal of Medical Sciences
null
Does The Course Of Laboratory Parameters Help Us To Predict The Outcome Of Cchf?, Sümeyye Kazancioğlu, Esragül Akinci, Ali̇ye Baştuğ, Bi̇rcan Kayaaslan, Ayşe But, Hali̇de Aslaner, Seli̇m Sirri Eren, Meltem Arzu Yetki̇n, Hurrem Bodur
Does The Course Of Laboratory Parameters Help Us To Predict The Outcome Of Cchf?, Sümeyye Kazancioğlu, Esragül Akinci, Ali̇ye Baştuğ, Bi̇rcan Kayaaslan, Ayşe But, Hali̇de Aslaner, Seli̇m Sirri Eren, Meltem Arzu Yetki̇n, Hurrem Bodur
Turkish Journal of Medical Sciences
Abstrat Background/aim: This study was performed to identify the characteristics distinguishing fatal and nonfatal cases of patients diagnosed with Crimean-Congo hemorrhagic fever (CCHF). Materials and methods: A total of 92 patients with confirmed diagnosis of CCHF in 2009-2013 were included in the study. Results: A high level of urea and aPTT on the third day of hospital stay, diarrhea, somnolence, and the interval from the beginning of the symptoms to hospital admission were independently associated with fatality. Each 10-unit increase in aPTT and urea levels increased the fatality rate by 3.379-fold and 1.236-fold, respectively. Delay in hospital admission increased the …
Serological Prevalence Of Human Parvovirus B19 In Diseases Or Disordersrelated To Different Human Body Systems, Osman Aktaş, Hakan Aydin, Hakan Uslu
Serological Prevalence Of Human Parvovirus B19 In Diseases Or Disordersrelated To Different Human Body Systems, Osman Aktaş, Hakan Aydin, Hakan Uslu
Turkish Journal of Medical Sciences
Background/aim: Human parvovirus B19 is a pathogen that affects different parts of the body. We planned this study because of the lack of data on B19 seroprevalence based on different body-system diseases. Materials and methods: The prevalence of parvovirus B19 antibodies was investigated retrospectively in 1239 patients by review of medical records from 2009-2012, according to their diseases classified under general titles in compliance with the International Classification of Diseases (ICD-10). Parvovirus B19-specific antibodies were detected by quantitative enzyme immunoassays. Results: The positivity rate was 27.8% for only IgG, 8.5% for only IgM, and 2.6% for both IgG and IgM. …
Initial Experience With Delivery Of Palliative Care To Terminal Cancer Patients, Mustafa Süren, İsmai̇l Okan, Zi̇ya Kaya, Serkan Karaman, Semi̇h Arici, Mevlüt Çömlekçi̇, Murat Ayan, Mehmet Esen, Serkan Doğru, Aynur Şahi̇n, Tuğba Karaman
Initial Experience With Delivery Of Palliative Care To Terminal Cancer Patients, Mustafa Süren, İsmai̇l Okan, Zi̇ya Kaya, Serkan Karaman, Semi̇h Arici, Mevlüt Çömlekçi̇, Murat Ayan, Mehmet Esen, Serkan Doğru, Aynur Şahi̇n, Tuğba Karaman
Turkish Journal of Medical Sciences
No abstract provided.
Management Of Hyperbilirubinemia In Preterm Infants In Turkey, Ni̇lüfer Güzoğlu, Ümi̇t Ayşe Tandircioğlu, Di̇dem Ali̇efendi̇oğlu
Management Of Hyperbilirubinemia In Preterm Infants In Turkey, Ni̇lüfer Güzoğlu, Ümi̇t Ayşe Tandircioğlu, Di̇dem Ali̇efendi̇oğlu
Turkish Journal of Medical Sciences
Background/aim: Prematurity is a significant risk factor for developing unconjugated hyperbilirubinemia. This study investigated the current approach to managing hyperbilirubinemia in preterm newborns in Turkey. Materials and methods: A study-specific questionnaire on the management of jaundice in preterm infants was sent to 100 level III neonatal intensive care units in Turkey. Results: Responses were obtained from 84 centers from all regions of Turkey. Of the centers, 75.3% used the Turkish Neonatology Society guidelines for deciding to start phototherapy, and 24.7% used different guidelines. The monitoring of bilirubin varied among the participants. Of the participants, 53.6% believed that prophylactic phototherapy was …
Evaluation And Identification Of Idua Gene Mutations In Turkishpatients With Mucopolysaccharidosis Type I, Nazente Atçeken, Riza Köksal Özgül, Di̇dem Yücel Yilmaz, Ayşegül Tokatli, Turgay Coşkun, Hati̇ce Serap Si̇vri̇, Ali̇ Dursun, Mehmet Karaca
Evaluation And Identification Of Idua Gene Mutations In Turkishpatients With Mucopolysaccharidosis Type I, Nazente Atçeken, Riza Köksal Özgül, Di̇dem Yücel Yilmaz, Ayşegül Tokatli, Turgay Coşkun, Hati̇ce Serap Si̇vri̇, Ali̇ Dursun, Mehmet Karaca
Turkish Journal of Medical Sciences
Background/aim: This study aimed to identify IDUA gene mutations in Turkish patients morphologically (phenotypic) diagnosed with MPS type I. It also sought to discuss the possible effects of detected mutations on alpha-L-iduronidase enzyme function based on current knowledge. Materials and methods: Genetic analysis was carried out in 15 patients using direct DNA sequencing. Moreover, segregation analysis was performed among family members to predict the pathogenic effect of novel mutations, and computational programs were used to predict their functional impact. Results: Nine different mutations (c.494-1G>A, c.793-6C>G, c.793-5C>A, p.M1L, p.Y64X, p.A327P, p.W402X, p.P533L, and p.R628X) were identified. Computational analysis …
Posterior Laminoforaminotomy In The Treatment Of Lateralcervical Herniated Disc And Foraminal Stenosis, Hakan Yilmaz, Ali̇ Riza Ertürk, Ayşe Karataş, İbrahi̇m Burak Atci, Alaetti̇n Yurt
Posterior Laminoforaminotomy In The Treatment Of Lateralcervical Herniated Disc And Foraminal Stenosis, Hakan Yilmaz, Ali̇ Riza Ertürk, Ayşe Karataş, İbrahi̇m Burak Atci, Alaetti̇n Yurt
Turkish Journal of Medical Sciences
Background/aim: Posterior cervical laminoforaminotomy is an effective surgical treatment in selected cases of cervical radiculopathy caused by posterolateral herniated discs or foraminal stenosis. The aim of the present study was to evaluate the surgical techniques, rates of complications, long-term outcomes, advantages, and disadvantages of keyhole foraminotomy retrospectively. Materials and methods: Keyhole foraminotomy was performed in 83 patients. In 51 patients (61.5%) soft disc herniation was removed, and in 32 of them (38.5%) osteophytes were evident. The clinical data were evaluated according to Odom's criteria, and the mean follow-up time was 6 months. Results: Postoperative results were classed as excellent in …
Is Silicone Stent Insertion A Clinically Useful Option For Tracheobronchomalacia?, Levent Dalar, Seda Tural Önür, Cengi̇z Özdemi̇r, Si̇nem Nedi̇me Sökücü, Ahmet Levent Karasulu, Sedat Altin
Is Silicone Stent Insertion A Clinically Useful Option For Tracheobronchomalacia?, Levent Dalar, Seda Tural Önür, Cengi̇z Özdemi̇r, Si̇nem Nedi̇me Sökücü, Ahmet Levent Karasulu, Sedat Altin
Turkish Journal of Medical Sciences
Background/aim: Tracheobronchomalacia (TBM) leads to the obstruction of expiratory airflow and interference with secretion clearance. Stabilization of the airway wall using a silicon stent or laser coagulation of the posterior wall may be treatment options.1397645907This study aimed to retrospectively analyze which interventional bronchoscopic method could be used to provide airway stabilization and gain control of symptoms and for whom this method could be used. Materials and methods: Fifteen patients who had received treatment in our interventional pulmonology unit were analyzed. We analyzed the techniques used, stent duration, complications, and long-term treatment success retrospectively. Results: Stents were used in 10 patients: …
Review Of 306 Evisceration Surgeries Performed Between 2005 And 2013, Özgür Balta, Uğur Acar, Fatma Akbaş Kocaoğlu, Fi̇rdevs Örnek
Review Of 306 Evisceration Surgeries Performed Between 2005 And 2013, Özgür Balta, Uğur Acar, Fatma Akbaş Kocaoğlu, Fi̇rdevs Örnek
Turkish Journal of Medical Sciences
Background/aim: The purpose of the present study was to evaluate the reasons for eye evisceration surgeries performed from 2005 to 2013 in our clinic. Materials and methods: The medical records of patients who underwent evisceration surgery over the past 9 years were retrospectively evaluated. Detailed data were reviewed, with a focus on the first precipitating factor for evisceration. Results: Of the 306 patients who underwent evisceration surgery in the studied period, 111 (36.27%) were female (with a mean age of 41.56 ± 21.38 years) and 195 (63.73%) were male (with a mean age of 37.76 ± 21.92 years). The most …
Nail Changes In Patients With Inflammatory Bowel Diseases, Özlem Eki̇z, Ebru Çeli̇k, İlknur Balta, Bi̇lge Bülbül Şen, Emi̇ne Nur Ri̇fai̇oğlu, Mehmet Demi̇r, Fuat Eki̇z, Ömer Başar, Osman Yüksel
Nail Changes In Patients With Inflammatory Bowel Diseases, Özlem Eki̇z, Ebru Çeli̇k, İlknur Balta, Bi̇lge Bülbül Şen, Emi̇ne Nur Ri̇fai̇oğlu, Mehmet Demi̇r, Fuat Eki̇z, Ömer Başar, Osman Yüksel
Turkish Journal of Medical Sciences
Background/aim: Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. To our knowledge, no studies to date pertain to the profile of nail changes in IBD, except for onychomycosis. We aimed to study the frequency and pattern of nail changes among patients with IBD and evaluate their potential relationships with several parameters in IBD. Materials and methods: The study included 73 patients with IBD and 51 healthy control subjects. Nails of both groups were examined for changes with regard to color, striations, texture, curvature of nail plates, dystrophy of nail plates, and pigmentation. …
Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz
Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz
Turkish Journal of Medical Sciences
Background/aim: The purpose of the present study was to identify traditional practices and the extent to which they are practiced by mothers during pregnancy, birth, the postpartum period, and newborn care. Materials and methods: This study was conducted in the city center of Konya (Turkey). Data were collected through questionnaires completed by volunteers. The research sample comprised 450 mothers, all of whom had given birth to at least one live baby. The forms were completed during face-to-face interviews. Results: Some traditional pregnancy practices were followed by 70.7% of the participants. Of the women who performed these practices, 57.4% consciously chose …
Comparison Between The Protective Effects Of Vitamin K And Vitamin A On The Modulation Of Hypervitaminosis D3 Short-Term Toxicity In Adult Albino Rats, Said Said Elshama, Hosam-Eldin Hussein Osman, Ayman El-Meghawry El-Kenawy, Hamdi Mohamed Youseef
Comparison Between The Protective Effects Of Vitamin K And Vitamin A On The Modulation Of Hypervitaminosis D3 Short-Term Toxicity In Adult Albino Rats, Said Said Elshama, Hosam-Eldin Hussein Osman, Ayman El-Meghawry El-Kenawy, Hamdi Mohamed Youseef
Turkish Journal of Medical Sciences
Background/aim: Vitamin D3 has increased risk of toxicity due to its common use in multivitamin preparations. Vitamin K and vitamin A play an important role in vitamin D action. The goal of the current study was to compare the protective effects of vitamin K and vitamin A on the modulation of hypervitaminosis D3 toxicity in rats by assessing serum calcium, renal function tests, cardiac enzymes, and related histopathological changes. Materials and methods: Eighty adult albino rats were divided into four groups; each group consisted of 20 rats. The first group received water; the second received a toxic dose of vitamin …
Ameliorating Effects Of Curcumin On Nicotine-Induced Mice Testes, Gülfi̇dan Coşkun, Hülya Özgür, Şaban Doran, Sai̇t Polat
Ameliorating Effects Of Curcumin On Nicotine-Induced Mice Testes, Gülfi̇dan Coşkun, Hülya Özgür, Şaban Doran, Sai̇t Polat
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the antioxidative effect of curcumin on nicotine-induced mice testis. Materials and methods: Sixty Swiss albino male mice were divided into five groups, each containing 12 mice. The first group was used as a control. To induce toxicity in the second and third group, nicotine (0.4 mg/kg/day) was injected intraperitoneally into mice for 14 and 28 days, respectively. The mice in the fourth and fifth group were injected with nicotine (0.4 mg/kg/day) and orally treated with curcumin (200 mg/kg) for 14 and 28 days, respectively. Testosterone levels were measured from blood samples …
The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen
The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen
Turkish Journal of Medical Sciences
Background/aim: To investigate the efficiency of Capparis ovata as a protective agent against acute paracetamol toxicity of the liver. Materials and methods: A total of 36 Wistar albino rats were divided into 4 groups: 1) paracetamol, 2) Capparis ovata + paracetamol, 3) Capparis ovata, and 4) control. Groups 2 and 3 were given Capparis ovata and Groups 1 and 4 distilled water for 8 days. On day 8, 3000 mg kg-1 paracetamol was administered orally to Groups 1 and 2. Samples were taken on day 9. AST, ALT, total bilirubin, direct bilirubin, GGT, and ALP levels were assessed. Lipid peroxidation …
Effectiveness Of P6 Acupoint Electrical Stimulation In Preventing Postoperativenausea And Vomiting Following Laparoscopic Surgery, Aik Hoe Yeoh, Shereen Suet Ping Tang, Norsidah Abdul Manap, Wan Rahiza Wan Mat, Shuraya Said, Muhamad Rahimi Che Hassan, Raha Abdul Rahman
Effectiveness Of P6 Acupoint Electrical Stimulation In Preventing Postoperativenausea And Vomiting Following Laparoscopic Surgery, Aik Hoe Yeoh, Shereen Suet Ping Tang, Norsidah Abdul Manap, Wan Rahiza Wan Mat, Shuraya Said, Muhamad Rahimi Che Hassan, Raha Abdul Rahman
Turkish Journal of Medical Sciences
Background/aim: The effects of pericardium 6 (P6) electrical stimulation in patients at risk of postoperative nausea and vomiting (PONV) following laparoscopic surgery were evaluated. Materials and methods: Eighty patients for laparoscopic surgery with at least one of the determined risks (nonsmoker, female, previous PONV/motion sickness, or postoperative opioid use) were randomized into either an active or sham group. At the end of surgery, Reletex electrical acustimulation was placed at the P6 acupoint. The active group had grade 3 strength and the sham group had inactivated electrodes covered by silicone. It was worn for 24 h following surgery. PONV scores were …
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Turkish Journal of Medical Sciences
Background/aim: To assess the immune status against tetanus in relation to self-declared vaccination status among an adult population in Yozgat, Turkey. Methods: Questionnaires and blood specimens were collected from 267 individuals over 18 years of age in Yozgat, Turkey. Antitetanus antibodies were determined quantitatively by enzyme-linked immunosorbent assay. Results: Among the 267 subjects (mean age 43.4 ± 15.6; male:female, 133:134) 168 (62.9%) had protective level of tetanus antibody titers. There was a characteristic distribution of the tetanus antibody titers in different age groups as it dropped with increasing age. Protective immunity was obtained in 74.1% of urban and 47.9% of …
Celiac Disease In Children With Chronic Constipation, Murat Çakir, Seçi̇l Cezaroğlu, Ümi̇t Çobanoğlu
Celiac Disease In Children With Chronic Constipation, Murat Çakir, Seçi̇l Cezaroğlu, Ümi̇t Çobanoğlu
Turkish Journal of Medical Sciences
Background/aim: Chronic constipation (CC) and celiac disease (CD) are the most common conditions encountered in pediatric gastroenterology. The association of these two disorders has not been evaluated properly. We analyzed the prevalence and outcome of CD in children with CC. Materials and methods: The study included children with CC (n = 313) and healthy children (n = 990). Serum IgA and IgA antitissue transglutaminase antibodies (IgA-tTG) were studied in all subjects. Intestinal biopsy and HLA-DQ2/DQ8 typing was performed in subjects with elevated IgA-tTG. Results: Serology was positive in 8 children (2.5%) with CC and 6 children (0.6%) from the control …
Premenstrual Syndrome And Life Quality In Turkish Health Science Students, Hati̇ce Işik, Şule Ergöl, Öner Aynioğlu, Ahmet Şahbaz, Ayşe Kuzu, Müge Uzun
Premenstrual Syndrome And Life Quality In Turkish Health Science Students, Hati̇ce Işik, Şule Ergöl, Öner Aynioğlu, Ahmet Şahbaz, Ayşe Kuzu, Müge Uzun
Turkish Journal of Medical Sciences
Background/aim: The purpose of the present study was to investigate the incidence of PMS, risk factors affecting PMS symptoms, and life quality in health science students. Materials and methods: A total of 608 volunteer female students studying at the health campus of a state university in Turkey were included in the study. The participants were asked to fill out questionnaires on sociodemographic data, PMS symptoms, and SF-36 life quality tests. Results: The overall frequency of PMS among participants was 84.5%. The average PMS and general health SF scores were 118.34 ± 37.3 and 20.03 ± 3.72, respectively. Students who had …
Evaluation Of The Relationship Between Migraine Disorder Andoral Comorbidities: Multicenter Randomized Clinical Trial, Cem Peşkersoy, Şule Peker, Ayşegül Kaya, Aycan Ünalp, Necmi̇ Gökay
Evaluation Of The Relationship Between Migraine Disorder Andoral Comorbidities: Multicenter Randomized Clinical Trial, Cem Peşkersoy, Şule Peker, Ayşegül Kaya, Aycan Ünalp, Necmi̇ Gökay
Turkish Journal of Medical Sciences
Background/aim: Although migraine is a common disorder, there is a lack of research investigating the possible relationship between migraine and oral health. The aim of the present study was to explore the relationship between temporomandibular disorders, bruxism, dental caries, periodontal status, and migraine disorder in a multicenter, parallel, case-controlled clinical study. Materials and methods: A total of 2001 participants were divided into two groups: migraineurs (nm = 998) and nonmigraineurs (nh = 1003). International Headache Society's Second Edition of International Classification of Headache Disorders and modified Migraine Disability Assessment surveys were administered to evaluate the level of migraine; a pretreatment …
Effects Of A Self-Management Educational Program On Metabolic Control In Type 2 Diabetes, Hosein Ali Sadeghian, Sri Venkata Madu, Kamal Agrawal, Aanjor Tupil Kannan, Kireet Agrawal
Effects Of A Self-Management Educational Program On Metabolic Control In Type 2 Diabetes, Hosein Ali Sadeghian, Sri Venkata Madu, Kamal Agrawal, Aanjor Tupil Kannan, Kireet Agrawal
Turkish Journal of Medical Sciences
Background/aim: India has 63 million diabetic people and the overall prevalence of diabetes in this country is 8.37%. Lifestyle modification by education is the most cost-effective strategy to have better metabolic control. The aim of this study was to investigate the effects of a self-management educational program on control of type 2 diabetes Materials and methods: It was a randomized controlled interventional study conducted among 306 patients with type 2 diabetes mellitus attending the Diabetic Clinic at G.T.B. Hospital, Delhi, from March 2010 to May 2013. The intervention was in the form of group education based on a self-management program, …
Investigation Of Enteropathogenic Escherichia Coli And Shiga Toxin-Producing Escherichia Coli Associated With Hemolytic Uremic Syndrome In İzmir Province, Turkey, Eli̇f Bozçal, Gürkan Yi̇ği̇ttürk, Ataç Uzel, Sabi̇re Şöhret Aydemi̇r
Investigation Of Enteropathogenic Escherichia Coli And Shiga Toxin-Producing Escherichia Coli Associated With Hemolytic Uremic Syndrome In İzmir Province, Turkey, Eli̇f Bozçal, Gürkan Yi̇ği̇ttürk, Ataç Uzel, Sabi̇re Şöhret Aydemi̇r
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to investigate Shiga toxin-producing Escherichia coli (STEC) and enteropathogenic Escherichia coli (EPEC) strains originating from diarrheagenic patients. Materials and methods: A total of 102 patients with diarrhea between October 2012 and January 2013 were enrolled in this study. Multiplex and standard polymerase chain reactions were performed to detect and distinguish STEC and EPEC strains. O serotyping of EPEC was carried out by monovalent antisera. The O and H serotyping of STEC strains was performed at the Refik Saydam Institute, Ankara. Results: A total of 5 (3.42%) strains were identified as STEC, and 3 …
Sevoflurane Versus Propofol For Electroconvulsive Therapy: Effects On Seizure Parameters, Anesthesia Recovery, And The Bispectral Index, Melekşah Pekel, Nadi̇de Aysun Postaci, İsmai̇l Aytaç, Derya Karasu, Hüseyi̇n Keleş, Özlem Şen, Bayazi̇t Di̇kmen, Erol Göka
Sevoflurane Versus Propofol For Electroconvulsive Therapy: Effects On Seizure Parameters, Anesthesia Recovery, And The Bispectral Index, Melekşah Pekel, Nadi̇de Aysun Postaci, İsmai̇l Aytaç, Derya Karasu, Hüseyi̇n Keleş, Özlem Şen, Bayazi̇t Di̇kmen, Erol Göka
Turkish Journal of Medical Sciences
Background/aim: In this prospective randomized cross-over study we compare the effects of sevoflurane versus propofol for electroconvulsive therapy (ECT) anesthesia. Materials and methods: Twenty four patients (ASA I-III, 18-65 years old) receiving ECT three times per week were included. Anesthesia was induced with either propofol (0.75 mg/kg iv) or 5% sevoflurane in 100% oxygen. Consecutive ECT sessions followed a 2 × 2 crossover design and a 2-day washout period until the 10th ECT. Intravenous succinylcholine (1 mg/kg) was administered while bispectral index (BIS) values were ≤60%. Results: Electromyogram and electroencephalogram seizure duration, postictal suppression index, BIS values, mean arterial blood …
Levels Of Nitric Oxide, Asymmetric Dimethyl Arginine, Symmetric Dimethyl Arginine,And L-Arginine In Patients With Obsessive-Compulsive Disorder, Enver Demi̇rel Yilmaz, Mehmet Fati̇h Üstündağ, Ali̇ Görkem Gençer, Yüksel Kivrak, Özge Ünal, Mustafa Bi̇li̇ci̇
Levels Of Nitric Oxide, Asymmetric Dimethyl Arginine, Symmetric Dimethyl Arginine,And L-Arginine In Patients With Obsessive-Compulsive Disorder, Enver Demi̇rel Yilmaz, Mehmet Fati̇h Üstündağ, Ali̇ Görkem Gençer, Yüksel Kivrak, Özge Ünal, Mustafa Bi̇li̇ci̇
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate and compare to healthy controls the variations in the levels of nitric oxide (NO), asymmetric dimethyl arginine (ADMA), symmetric dimethyl arginine (SDMA), and L-arginine levels in patients with obsessive-compulsive disorder (OCD). Materials and methods: We enrolled 30 patients with OCD and 30 healthy controls in the study consecutively. Diagnostic interviews of all participants were conducted with the Structured Clinical Interview for Axis I Disorders (SCID-I), and sociodemographic data of the participants were recorded. Patients scoring 10 points or more on the Yale-Brown Obsessive-Compulsive Scale were enrolled in the study. Results: The NO levels of patients …
Nf-?? And Sod Expression In Preeclamptic Placentas, Abraham Silva Carmona, Hugo Mendieta Zeron
Nf-?? And Sod Expression In Preeclamptic Placentas, Abraham Silva Carmona, Hugo Mendieta Zeron
Turkish Journal of Medical Sciences
Background/aim: Preeclampsia is a leading cause of maternal death in the developing world. Our aim was to quantify and compare messenger (mRNA) expression of nuclear factor-kappa beta (NF-?β) and superoxide dismutase (SOD) in control patients with preeclampsia and without preeclampsia with or without familial hereditary background. Materials and methods: Four groups of patients were formed depending on the presence or absence of preeclampsia and presence or absence of familial history for preeclampsia. NF-?β and SOD were measured in human placentas by real-time quantitative polymerase chain reaction. The 2-ΔΔct analysis method was used to measure the difference in the relative expression …
Potential Drug?Drug Interactions In A Medical Intensive Care Unit Of A University Hospital, Medi̇ne Gülçebi̇ İdri̇z Oğlu, Esra Küçüki̇brahi̇moğlu, Ati̇la Karaalp, Özlem Sarikaya, Mahluga Demirkapu, Fi̇li̇z Onat, Mehmet Zafer Gören
Potential Drug?Drug Interactions In A Medical Intensive Care Unit Of A University Hospital, Medi̇ne Gülçebi̇ İdri̇z Oğlu, Esra Küçüki̇brahi̇moğlu, Ati̇la Karaalp, Özlem Sarikaya, Mahluga Demirkapu, Fi̇li̇z Onat, Mehmet Zafer Gören
Turkish Journal of Medical Sciences
Background/aim: Drug-drug interactions (DDIs) can impact patient safety. Occurrence of clinically important DDIs is higher for intensive care unit (ICU) patients. This observational study aimed to evaluate the potential DDIs in medical ICU patients of a university hospital. Materials and methods: The Medical Pharmacology Department organized consultation reports for ICU patients in order to detect the DDIs. To focus on clinically important DDIs, interactions in the C, D, or X risk rating categories of the Lexi-Interact online database were analyzed. Frequency and clinical risk rating categories of DDIs were detected. Relationship between number of prescriptions and DDIs were assessed. The …
Evaluation Of The Gastrointestinal Findings Of Nodulocystic Acnepatients During Systemic Isotretinoin Therapy, Duru Tabanlioğlu Onan, Burcu Hazar Tantoğlu, Nuran Alli, Seçi̇l Özkan, Ufuk Samsar, Hasan Tankut Köseoğlu, Refi̇ka Ferda Artüz
Evaluation Of The Gastrointestinal Findings Of Nodulocystic Acnepatients During Systemic Isotretinoin Therapy, Duru Tabanlioğlu Onan, Burcu Hazar Tantoğlu, Nuran Alli, Seçi̇l Özkan, Ufuk Samsar, Hasan Tankut Köseoğlu, Refi̇ka Ferda Artüz
Turkish Journal of Medical Sciences
Background/aim: Systemic isotretinoin treatment is an effective treatment modality for nodulocystic acne, the clinical use of which has been associated with reports of adverse events. We conducted a prospective study with the aim of determining the possible gastrointestinal and laboratory findings of nodulocystic acne patients during systemic isotretinoin treatment. Materials and methods: Seventy patients with nodulocystic acne completed the study. During the monthly follow-up visits, liver function tests and lipid profiles of the patients were evaluated and gastrointestinal system complaints were examined. Results: We recorded a significant elevation in liver function tests and lipid profiles of the patients, the most …
Determination Of Virulence And Multidrug Resistance Genes With Polymerase Chain Reaction Method In Vancomycin-Sensitive And -Resistant Enterococci Isolated From Clinical Samples*, Şükran Saba Çopur, Fi̇kret Şahi̇n, Juli̇de Sedef Göçmen
Determination Of Virulence And Multidrug Resistance Genes With Polymerase Chain Reaction Method In Vancomycin-Sensitive And -Resistant Enterococci Isolated From Clinical Samples*, Şükran Saba Çopur, Fi̇kret Şahi̇n, Juli̇de Sedef Göçmen
Turkish Journal of Medical Sciences
Background/aim: Enterococci play an important role in nosocomial infections. Therefore, this study investigates multidrug resistance (MDR)1 gene areas in the pathogenicity of enterococci and virulence genes in both vancomycin-sensitive enterococci (VSE) and vancomycin-resistant enterococci (VRE) strains. Materials and methods: Virulence genes and MDR genes of enterococci were investigated by polymerase chain reaction (PCR). Results: We evaluated a total of 116 isolates, 93 being VRE and 23 being VSE. In this study, 95.6% of VRE (n = 93) were Enterococcus faecium (n = 89) and 4.3% were E. faecalis (n = 4), while 17.4% of VSE (n = 23) were E. …
Investigating The In Vitro Synergistic Activities Of Several Antibiotic Combinationsagainst Carbapenem-Resistant Acinetobacter Baumannii Isolates, Sevi̇m Yavaş, Meltem Arzu Yetki̇n, Bi̇rcan Kayaaslan, Ali̇ye Baştuğ, Hali̇de Aslaner, Ayşe But, Di̇lek Kanyilmaz, Berri̇n Sari, Esragül Akinci, Hurrem Bodur
Investigating The In Vitro Synergistic Activities Of Several Antibiotic Combinationsagainst Carbapenem-Resistant Acinetobacter Baumannii Isolates, Sevi̇m Yavaş, Meltem Arzu Yetki̇n, Bi̇rcan Kayaaslan, Ali̇ye Baştuğ, Hali̇de Aslaner, Ayşe But, Di̇lek Kanyilmaz, Berri̇n Sari, Esragül Akinci, Hurrem Bodur
Turkish Journal of Medical Sciences
Background/aim: Acinetobacter baumannii (A. baumannii) is one of the most common healthcare-associated infectious agents worldwide. The aim of this study was to investigate the in vitro synergistic activities of several antibiotic combinations against carbapenem-resistant (CR) A. baumannii isolates. Materials and methods: Eighteen CR A. baumannii strains were isolated from the patients who were hospitalized in the intensive care unit between June 2012 and August 2012. The in vitro effects of single and binary combinations of meropenem (MEM), colistin (CST), tigecycline (TGC), and sulbactam (SUL) on these isolates were determined using the Epsilometer test (E-test) method. Results: All 18 isolates were …
An Investigation Of The Bactericidal Activity Of Chlorhexidine Digluconateagainst Multidrug-Resistant Hospital Isolates, Meli̇ke Eki̇zoğlu, Meral Sağiroğlu, Ekrem Kiliç, Ayşe Gülşen Hasçeli̇k
An Investigation Of The Bactericidal Activity Of Chlorhexidine Digluconateagainst Multidrug-Resistant Hospital Isolates, Meli̇ke Eki̇zoğlu, Meral Sağiroğlu, Ekrem Kiliç, Ayşe Gülşen Hasçeli̇k
Turkish Journal of Medical Sciences
Background/aim: Hospital infections are among the most prominent medical problems around the world. Using proper biocides1397645907in an appropriate way is critically important in overcoming this problem. Several reports have suggested that microorganisms may develop resistance or reduce their susceptibility to biocides, similar to the case with antibiotics. In this study we aimed to determine the antimicrobial activity of chlorhexidine digluconate against clinical isolates. Materials and methods: The susceptibility of 120 hospital isolated strains of 7 bacterial genera against chlorhexidine digluconate was determined by agar dilution test, using minimum inhibitory concentration (MIC) values and the EN 1040 Basic Bactericidal Activity Test …
Total White Blood Cell Count, Liver Enzymes, And Metabolic Syndrome In Schizophrenia, Görkem Karakaş Uğurlu, Semra Ulusoy Kaymak, Mustafa Uğurlu, Si̇bel Örsel, Ali̇ Çayköylü
Total White Blood Cell Count, Liver Enzymes, And Metabolic Syndrome In Schizophrenia, Görkem Karakaş Uğurlu, Semra Ulusoy Kaymak, Mustafa Uğurlu, Si̇bel Örsel, Ali̇ Çayköylü
Turkish Journal of Medical Sciences
Background/aim: Metabolic syndrome (MetS) is an important clinical issue in patients with schizophrenia, but its associated factors are still ambiguous. The aim of the present study was to test whether there are any associations between MetS and white blood cell (WBC) levels, liver enzymes, or sociodemographic variables. Materials and methods: The study included 91 patients with a diagnosis of schizophrenia. We used the National Cholesterol Education Program's Third Adult Treatment Protocol criteria to evaluate MetS in patients. Schizophrenia patients with MetS were compared with those without MetS on the basis of demographic and clinical characteristics and total WBC counts. We …