Digital Commons Network^™

Does Motor Skill Competence Influence Physical Activity Behavior? Focusing On Sport-Specific Skills, Yubing Wang, Yaogang Han, Pan Li, Bin Zhang

International Journal of Physical Activity and Health

The purpose of this study was to investigate the widely held belief that motor skill competence positively affects physical activity behavior (PA), considering the task-specific nature of motor skill competence and the context-specific nature of PA. Specifically, we examined the effects of students’ jump rope (JR) and basketball (BB) competence on their PA in six contexts. A total of 134 sixth grade students participated in this study. All variables were assessed using appropriate tools. A series of hierarchical regression analyses were conducted to address the research questions. Students’ JR competence did not significantly influence their PA in either JR-related or …

Scrotal Temperature Change During Running In Naked Humans, Yasuho Takii, Makoto Fukuda, Kazuyuki Kanosue, Tamae Yoda

Children’s Nutrition Research Center Staff Publications

Male reproductive organs are functionally affected by high body temperature. This study aimed to clarify the thermoregulation mechanisms of the human scrotum during running, and experiments were conducted to investigate temperature changes in the whole body and the scrotum. Eleven male long-distance runners performed treadmill running at 60%[Formula: see text] for 60 min in an indoor environment at 27 °C and 40% relative humidity. Immediately after the start of the run, the skin temperatures in areas other than the scrotum decreased or showed a tendency to decrease. In contrast, the scrotal temperature increased immediately after the start of the run. …

Streamflow Reconstruction For The Upper Indus Basin, Syeda Saria Bukhary, Sajjad Ahmad

Civil and Environmental Engineering and Construction Faculty Research

The sustainability of water resources in Pakistan faces mounting challenges due to population growth, climate change, and declining groundwater reserves. The Indus River, vital for the country’s agriculture, energy, and economy, suffers from limited instrumental discharge records that do not capture long-term hydrologic variability or extreme flow events. This study addressed this gap by developing streamflow reconstructions for the Upper Indus Basin (UIB) using tree-ring chronologies (TRC) combined with sea surface temperature (SST) data—an approach not previously applied in this region—for four discharge stations: Partab, Daniyor, Besham Qila, and Kachora. Stepwise linear regression models using TRC and SST predictors explained …

How Social, Behavioral, And Policy Factors Impact Water Satisfaction And Management In Urban Areas, Rafi Haikal, Thoriqi Firdaus, Siti Hilya Nabila, Rizqi Shafira Chairunnisa

Journal of Environmental Science and Sustainable Development

The issue of water management in Indonesia’s specific urban contexts, specifically in Surabaya as an industrial hub and Bali as a tourist destination, is of paramount importance due to its impact on public health and environmental sustainability. This study analyses water management and conservation factors by comparing two distinct urban areas. The research design employs Partial Least Squares Structural Equation Modelling (PLS-SEM), which involves a specialised approach for analysing the complex relationships between variables. The results of the analysis indicate that community attitudes in Surabaya, facilitated by infrastructure and technology, significantly predicts intention to perform (β=0.334, p<0.001) and water management satisfaction (β=0.409, p<0.001). In contrast, collaboration with the government enhances environmental constraints (β=0.285, p<0.003) and water management satisfaction (β=0.140, p<0.044). In Bali, where water management is based on traditional practices, community attitudes do not significantly affect water management satisfaction (β=0.095, p>0.431). Still, perceived …

Use Of Growing Degree Days To Model The Dynamics Of Aboveground Biomass And Nitrogen Accumulation Of Winter Cover Crops, M. Pessotto, Trenton Roberts, C. Dos Santos, K. A. Hoegenauer, M. Bertucci, W. J. Ross, M. Savin

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Cover cropping is an important management practice that can benefit the cash crop and the environment. Plant species, weather, and cover crop termination influence biomass production and N fixation potential. This study was conducted to determine optimal termination dates for production systems in Arkansas based on growing degree days (GDD) for eight different cover crop species: Austrian winter pea (AWP) (Pisum sativum), balansa clover (Trifolium michelianum), barley (Hordeum vulgare), black-seeded oats (Avena sativa), common vetch (Vicia sativa var. Cahaba), cereal rye (Secale cereale), crimson clover (Trifolium incarnatum), and hairy vetch (Vicia villosa). Field studies were conducted at three research stations …

Using Rattlesnake Venom To Model Complex Trait Evolution Across Ecological And Evolutionary Scales, Samuel R. Hirst

USF Tampa Graduate Theses and Dissertations

A central challenge in evolutionary biology is understanding how genetic variation leads to phenotypicdiversity, particularly for complex traits that strongly influence fitness. Traits form the substrate of natural selection, but it is genes, that are inherited across generations. To fully understand the evolutionary process, we must therefore connect the molecular basis of trait variation with the evolutionary outcomes of such traits.

For relatively simple traits, the genotype–phenotype relationship is well understood. Classic systems, such as coat color in beach mice or toxin resistance in garter snakes, have provided effective examples of how relatively few loci underlie conspicuous adaptive differences across …

Nasal Microbionts Differentially Colonize And Elicit Cytokines In Human Nasal Epithelial Organoids, Andrea I Boyd, Leah A Kafer, Isabel F Escapa, Amal Kambal, Hira Tariq, Susan G Hilsenbeck, Hoa Nguyen-Phuc, Anubama Rajan, Joshua M Lensmire, Kathryn A Patras, Pedro A Piedra, Sarah E Blutt, Katherine P Lemon

Faculty, Staff and Students Publications

Nasal colonization by Staphylococcus aureus or Streptococcus pneumoniae is associated with an increased risk of infection by these pathobionts, whereas nasal colonization by Dolosigranulum species is associated with health. Human nasal epithelial organoids (HNOs) differentiated at air-liquid interface (ALI) physiologically recapitulate human nasal respiratory epithelium with a robust mucociliary blanket. Due to their natural stem-like properties, HNO lines are a long-term experimental resource that offers genetic diversity based on the different donors. To develop HNOs as a new model system for bacterial nasal colonization, we reproducibly monocolonized HNOs differentiated at ALI with S. aureus, S. pneumoniae, or Dolosigranulum …

Spiny Orb Weaver, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic hardened, spiny abdomen. Spiny orb weaver spiders enjoy warm, tropical, and subtropical environments and are primarily found in the Southeastern U.S., the Caribbean, and South America. They live in wooded areas, citrus groves, and shrubby gardens. I’ve encountered spiny orb weaver spiders in my food forest where they like to set up their orb-shaped webs and feast on flies, mosquitoes, and moths.

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic …

Darkling Beetle, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Darkling beetles (Tenebrio molitor) are holometabolic insects. Darkling beetle is the common name of the large family of beetles Tenebrionidae which has more than 20,000 species. The T. molitor species gets its name from the yellowish appearance of the larvae. During its lifespan, a darkling beetle experiences a complete metamorphosis in four distinct stages: Egg, larva, pupa, and adult. The eggs hatch within 4 to 19 days after the female oviposits. It takes about 3 – 4 months for an egg to develop into an adult, or the beetle stage.

During the adult stage, the beetles are initially whitish and …

Horseshoe Crabs, Jessie M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Horseshoe crabs (Limulus polyphemus) are fascinating animals known as “living fossils.” Older than dinosaurs, horseshoe crabs are arthropods, closely related to spiders and scorpions. Many shorebirds, including red knot, depend on the eggs of horseshoe crabs during migration. Horseshoe crabs are captured and bled alive for their blue blood. Rich in limulus amebocyte lysate (LAL), their blood is used for the Limulus Amebocyte Lysate (LAL) test, which is used worldwide to detect bacterial toxins in pharmaceuticals and medical devices.

Horseshoe crabs have an intricate anatomy, so I spent a lot of time researching it before I started drawing them. When …

Floridians, Michael Anglim-Lindros

PANDION: The Osprey Journal of Research and Ideas

The purpose of this piece is to explore species present in Florida by depicting native species alongside commonly seen non-native ones. I decided to focus on mammals, specifically those I have personally observed while living in North Florida. By illustrating their unadorned skeletal remains, I hope to inspire viewers to consider the similarities, differences, and relationships among these organisms, as well as the lives they lead on shared land.

The species depicted in this piece are (clockwise from middle) Homo sapiens (human) - non-native; Tadarida brasiliensis (Mexican free-tailed bat); Dasypus novemcinctus (nine-banded armadillo); Sciurus niger shermani (Sherman’s fox squirrel); Odocoileus …

Probiotic Intervention In Managing Chronic Stress, Bianca Opdenbosch

PANDION: The Osprey Journal of Research and Ideas

Chronic stress can induce gut dysbiosis which contributes to the dysregulation of the gut-brain axis and leads to anxiety and depressive-like symptoms. The gut-brain axis relies on nervous, immune, and endocrine interactions. Gut dysbiosis, an imbalance within the gut microbiome, disrupts gut-brain communication, impairing gut barrier integrity, inflammation regulation, and hormonal and neurotransmitter production. These gut changes contribute to mood disorders resulting from stress, and thus it is important to implement dietary interventions, like probiotics, to help mitigate these effects. Research highlights the potential of probiotics to act as an intervention to combat stress-induced gut dysbiosis and replenish beneficial bacteria …

Rewilding The Built Environment: Navigating Economic, Political, And Social Barriers To Urban Ecological Restoration, Carly E. Smith

PANDION: The Osprey Journal of Research and Ideas

Urban rewilding offers a nature-based approach to restoring ecological processes in cities while advancing climate resilience, biodiversity, and public well-being. Unlike conventional green infrastructure, rewilding allows ecosystems to develop with minimal intervention, emphasizing succession, complexity, and long-term adaptability. This paper examines the political, economic, and social factors that frame how rewilding is understood and implemented in urban planning. Governmental frameworks often prioritize order, predictability, and short-term results, making it difficult to accommodate the uncertainty and ecological complexity that rewilding requires. Economic models struggle to capture its long-term value, frequently overlooking ecosystem services or reconciling competing land uses. Social perceptions of …

Analysis Of Mct-1 Expression In Mouse Neural Retina In Response To Chronic Inflammation, Ian W. Ronson

PANDION: The Osprey Journal of Research and Ideas

Chronic inflammation is a current public health concern as it is linked to the etiology and symptoms of numerous diseases, for example diabetic retinopathy (DR). In the case of DR, inflammation leads to dysregulation of the blood retina barrier causing retinal hemorrhage and macular edema leading ultimately to irreversible vision loss. MCT-1 is critical for the survival of photoreceptor cells because MCT-1 forms protein complexes with Basigin, a cell-cell adhesion protein, that enables Müller glial cells to efficiently provide lactate as a high energy fuel source. Previous studies have shown chronic inflammation reduces Basigin expression in the retina and that …

Enzymes Of Calendula Officinalis L. As Affected By Foliar Application Of Nano-Nitrogen And Potassium Fertilizers, Under Water Stress Conditions, Aqeel Abdulabbas Alsudani, Qais Hussain Abbas Al-Semmak

Karbala International Journal of Modern Science

Water stress is a major environmental factor that limits the growth and productivity of Calendula officinalis L. To alleviate its negative effects, recent approaches have increasingly focused on nano-fertilizers that enhance plant antioxidant defenses. This study therefore aimed to evaluate the effect of foliar application of nano-nitrogen (0, 2, and 4 mL L⁻¹) and nano-potassium (0, 2, and 4 g L⁻¹) fertilizers under two irrigation regimes (100% and 50% of field capacity) on the activity of key antioxidant enzymes, including catalase (CAT), superoxide dismutase (SOD), and peroxidase (POD). The results revealed that irrigation at 50% field capacity significantly increased CAT, …

Principles Of Environmentally Sustainable Agriculture For Building Resilient And Resource-Efficient Food Systems, Ramazan Çakmakçi, Songül Çakmakçi, Muhammet Fati̇h Çakmakçi

Turkish Journal of Biology

As the demand for greater quantities of higher-quality food grows with population expansion, climate change, urbanization, and unsustainable agricultural practices accelerate the loss of arable land, ultimately threatening agricultural sustainability. Population growth necessitates a transition to nutritious, safe, and healthy food production systems that ensure higher yields, less reduced waste, improved social outcomes, and the integration of economic, social, and environmental sustainability principles. Urgent global challenges such as resource depletion, biodiversity loss, and climate change necessitate the protection of ecosystems and the sustainable use of natural resources. Agricultural systems must enhance food production and supply productivity, strengthen system resilience, and …

Artificial Intelligence In Medical And Biological Research: Promise And Perils Of Chatgpt And Deepseek In Advancing Healthcare, Mahmut Enes Kayaalp, Onur Gülteki̇n, Serhat Akçaalan, Hami̇t Çağlayan Kahraman, Hüseyi̇n Nevzat Topçu, Gülşah Kavrul Kayaalp

Turkish Journal of Biology

Background/aim: Artificial intelligence (AI), particularly large language models (LLMs) such as ChatGPT and DeepSeek, is being increasingly applied in clinical care, research, and education. The aim of this review is to examine how these tools may transform the conduct of medical and biological research and to define their limitations.

Materials and methods: A narrative synthesis of the literature was performed, encompassing studies published between 2020 and 2025. Peer-reviewed journals, systematic reviews, and high-impact original research articles were included to ensure an evidence-based overview. The principle applications, validation metrics, and clinical implications across orthopedics, oncology, cardiology, internal medicine, and the biological …

A Systematic Review Of Machine Learning In Heart Disease Prediction, Tathagat Banerjee, İshak Paçal

Turkish Journal of Biology

Background/aim: Cardiovascular diseases (CVDs) are a leading cause of global mortality, prompting the need for advanced predictive tools. While machine learning (ML) offers a powerful solution, there are significant challenges to clinical translation. This systematic review synthesizes the current state of ML in heart disease prediction, evaluating algorithmic performance, data utilization, and key translational challenges.

Materials and methods: Following PRISMA guidelines, a systematic search of literature published up to 2025 was conducted. From an initial pool of over 2500 records, a rigorous screening process yielded 65 studies for in-depth qualitative synthesis.

Results: Analysis showed that ensemble learning models dominate prediction …

Royal Jelly With Ellagic Acid Inhibits The Glycolytic Pathway And Induces Apoptosis Through Multiple Pathways In Colorectal Cancer, Tuğba Kul Köprülü

Turkish Journal of Biology

Background/aim: Developing novel chemotherapeutics with high anticancer efficacy and low toxicity remains a critical challenge in oncology. Natural products have shown promise due to their multitargeted activity and favorable safety profiles. The present study investigates the combined anticancer effects of royal jelly (RJ) and ellagic acid (EA), two potent antioxidants of animal and plant origin.

Materials and methods: Royal jelly (RJ) and ellagic acid (EA) were applied to HT29 (ATCC HTB-38, Human colorectal adenocarcinoma), HCT116 (ATCC CCL-247, Human colorectal carcinoma) and BEAS-2B (ATCC CRL-3588, human bronchial epithelium) cell lines, and their antiproliferative effects were evaluated using a xCELLigence Real-Time Cell …

Differential Modulation Of Cisplatin Efficacy By Montelukast Sodium And Desloratadine In Lung Cancer, Seha Akduman, Büşra Yüksel, Di̇dem Teci̇mel, Ömer Faruk Bayrak, Di̇dem Seven, Fi̇kretti̇n Şahi̇n

Turkish Journal of Biology

Background/aim: Despite advances in treatment, achieving effective and durable responses with chemotherapy remains a significant challenge in lung cancer management. This study investigates the effects of montelukast sodium (MLS) and desloratadine (DES), alone and in combination with cisplatin (CIS), on cell viability, apoptosis, cell cycle distribution, and antioxidant gene expression in A549 and DMS114 lung cancer cell lines.

Materials and methods: Cells were treated with CIS, MLS, DES, and their combinations for 24–72 h. Cell viability was assessed via MTS assay; apoptosis and cell cycle progression were analyzed by flow cytometry. The expression of antioxidant-related genes (GPX4, GSR, GCLC) was …

Tumor-Specific Cytotoxicity Of Pyrazole-Based Chalcone Derivatives In Human Oral Squamous Cell Carcinoma Cell Lines, Mehtap Tuğrak Sakarya, Hali̇se İnci̇ Gül, Hiroshi Sakagami, Junko Nagai, Yoshihiro Uesawa, Kenjiro Bandow

Turkish Journal of Biology

Background/aim: Pyrazole-based chalcone hybrids are notable in medicinal chemistry for their potential biological activity, although their tumor-specific cytotoxicity and mechanisms remain unknown in OSCC cells. This first study of pyrazole-chalcone hybrids in OSCC cells explores the tumor-selective cytotoxic effects and underlying cell death mechanisms triggered by a series of 10 newly synthesized pyrazole-based compounds (MS1MS10) in OSCC cell lines. Material and methods: The cytotoxic effects of the compounds were assessed using the MTT assay on four human OSCC cell lines and three types of normal human oral cells. The tumor-selectivity index (TS) and potency-selectivity expression (PSE) were calculated, and active …

Microplastic Pollution In Marine Ecosystems: Sources, Impacts, Andstakeholder-Based Solutions, Seren Acarer Arat

Turkish Journal of Biology

Microplastics (MPs) are plastic particles of anthropogenic origin with a size range of 1–5000 μm. Marine MP pollution is increasingly recognized as a significant global environmental challenge. MPs, which enter marine ecosystems from land- and marine-based sources, pose physical, chemical, and biological risks due to the adsorption of various pollutants and the formation of biofilm layers. MPs are found in various organisms from lower to higher trophic levels of the marine food web. The negative effects of MPs on marine organisms depend on their abundance, their characteristics, and the exposure time of organisms to MPs. MPs can adversely affect various …

Application Of Biological And Green Nanomaterials In Wastewater Treatment: Techniques For The Effective Removal Of Dyes, Heavy Metals, And Organic Pollutants, Emi̇ne Sena Kazan Kaya, Zeynep Ci̇ğeroğlu, Tansel Kemerli̇ Kalbaran, Başak Temur Ergan, Zeynep Mi̇ne Şenol, Meral Yildirim Yalçin

Turkish Journal of Biology

Background/aim: Wastewater from industrial, agricultural, and residential sources poses significant environmental and public health risks due to the presence of dyes, heavy metals, and organic pollutants. Conventional treatment methods are often inadequate for the complete removal of these pollutants. Therefore, the development of sustainable, environmentally friendly, and highly efficient treatment techniques has become increasingly important. The aim of this review is to evaluate the application of biological and green nanomaterials in wastewater treatment and to compare their effectiveness against different types of pollutants (dyes, heavy metals, and organics).

Materials and methods: This review provides detailed information on the removal of …

A Review Of Deep Learning Architectures For Plant Disease Detection​, Yasi̇n Kaya, Ercan Gürsoy

Turkish Journal of Biology

Background/aim: The rapid advancement of deep learning (DL) has revolutionized plant disease detection by enabling highly accurate, image-based diagnostic solutions. This review provides a comprehensive synthesis of DL-based methodologies for plant disease detection, systematically structured around the key stages of the modeling pipeline, encompassing data acquisition, preprocessing, augmentation, classification, detection, segmentation, and deployment.

Materials and methods: The review focuses on evaluating convolutional neural network (CNN) architectures such as VGG, ResNet, EfficientNet, and DenseNet across diverse experimental contexts. Classification strategies are categorized according to their integration of visualization techniques (e.g., saliency maps, Grad-CAM) to enhance model interpretability, emphasizing the pivotal role …

Green Carbon Dots In The Era Of Ai: Sustainable Synthesis, Intelligent Drug Delivery, Advanced Diagnostics, And Bioimaging, Emi̇ne Sezer, Fulden Ulucan Karnak, Si̇nan Akgöl

Turkish Journal of Biology

Background/aim: Green carbon dots (GCDs) are a rapidly developing class of nanomaterials that are revolutionizing various scientific disciplines due to their unique optical properties, low toxicity, and sustainable synthesis. This review offers a comprehensive roadmap for the field, emphasizing the synergy between GCDs and artificial intelligence (AI).

Materials and methods: We begin by detailing the sustainable synthesis of GCDs, highlighting green chemistry principles and the transformative role of AI in optimizing their production. Subsequently, we explore the critical characterization of GCDs, including their structural, optical, and biocompatibility assessment. The core of this study explores the diverse biomedical applications of GCDs, …

Applications Of Transfer Learning In Sunflower Disease Detection: Advances, Challenges, And Future Directions, Yonis Gulzar

Turkish Journal of Biology

Background/aim: Sunflower (Helianthus annuus) is a crop of high economic and nutritional importance that continues to suffer significant yield losses due to foliar diseases. Traditional image-based and laboratory detection techniques remain limited by subjectivity, cost, and scalability. Transfer learning (TL) has recently emerged as an effective approach to overcoming these challenges involving the reuse of pretrained deep models for plant pathology tasks. Presented here is a systematic examination of recent TL-based studies on sunflower disease classification to identify prevailing trends, research gaps, and future opportunities.

Materials and methods: A structured Scopus query was employed to retrieve peer-reviewed articles published between …

Flavonoids And Phenolic Compounds: A Promising Avenue For Neurodegenerative Disease Therapy, Tesli̇me Özge Şahi̇n, Özge Cemali̇, Merve Özdemi̇r, Şeri̇fe Ayten, Duygu Ağagündüz

Turkish Journal of Biology

Background/aim: Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and ALS are characterized by a progressive loss of nerve cells, for which no definitive cure currently exists. These conditions share common pathological mechanisms, including chronic neuroinflammation, oxidative stress, protein aggregation, and mitochondrial dysfunction. Flavonoids and other plant-derived phenolic compounds have recently attracted attention for the treatment of such conditions due to their antiinflammatory and antioxidant properties. This review explores the neuroprotective mechanisms of flavonoids and evaluates their potential for the prevention and treatment of neurodegenerative diseases.

Materials and methods: A literature search of the Web of Science, PubMed, and ScienceDirect databases …

Hsa_Circ_0001776 Regulates The Progression Of Acute Myeloid Leukemia Through The Mir-1269b/Pten Axis, Yaoyao Wang, Xiancong Yang, Simin Rong, Xiaoxu Lan, Chenhui Ti, Weimiao Sun, Baohui Yin, Youjie Li, Yunxiao Sun

Turkish Journal of Biology

Background/aim: Acute myeloid leukemia (AML) is a malignant neoplasm arising from bone marrow hematopoietic stem cells. It is a common subtype of childhood leukemia and remains challenging to cure. Emerging evidence suggests that circular RNAs (circRNAs), a class of noncoding RNAs, play key regulatory roles in tumor biology. Among their various functions, circRNAs often act as ‘sponges’ for microRNAs (miRNAs), modulating gene expression posttranscriptionally. This study investigates the functional role and clinical relevance of hsa_circ_0001776 in AML.

Materials and methods: Three AML cell lines and 22 peripheral blood samples were analyzed. Differential expression analysis of circRNAs in a GSE dataset …

Evaluating Sh-Sy5y Cells As A Dopaminergic Neuronal Model: Morphological, Transcriptomic, And Proteomic Insights, Eylül Ece İşlek Camadan, Mehmet Sarihan, Murat Kasap, Gürler Akpinar, Eli̇fcan Koçyi̇ği̇t

Turkish Journal of Biology

Background/aim: The SH-SY5Y neuroblastoma cell line is a popular in vitro model for neurodegenerative disease research, especially Parkinson’s disease (PD) research, but its use is complicated by limitations like the persistence of neuroblastoma-like features, unstable differentiation, mitochondrial dysfunction, and cellular stress. To address these limitations, this study tested a blended, nine-day differentiation protocol that sequentially applied all-trans retinoic acid (RA), brain-derived neurotrophic factor (BDNF), and dibutyryl cyclic adenosine monophosphate (dbcAMP). By evaluating key neuronal, dopaminergic, and PD-related markers, the research aims to determine if these differentiated SH-SY5Y cells are a suitable model for studying PD.

Materials and methods: A blended …

The Effects Of The Combined Use Of Carbon Quantum Dots And Antibacterial Agents On Pathogenic Bacteria, Derya Doğanay, İbrahi̇m Serkan Avşar, Şevval Maral Özcan Aykol, Gamze Çamlik, Besa Bi̇lakaya, İsmai̇l Tuncer Deği̇m

Turkish Journal of Biology

Background/aim: This study evaluates the challenges associated with overcoming antimicrobial resistance and innovative approaches to combat multidrug-resistant (MDR) bacterial infections.

Materials and methods: Novel codoped carbon quantum dots (CCQDs) were synthesized using citric acid as the carbon source and L-cysteine as the nitrogen codoping atom. The formulation in which citric acid was retained was designated as CCQDs-1, whereas the purified version, from which citric acid was removed, was termed CCQDs-2. The antibacterial properties of CCQDs-1 and CCQDs-2 were compared using the agar well diffusion method. This study comprehensively characterizes these nanomaterials and evaluates their antibacterial potential, both alone and in …