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Reproductive Biology Of Hybopsis Amblops, The Bigeye Chub, In The Flint River Of Alabama, Crissy L. Tarver, Bruce W. Stallsmith Jan 2026

Reproductive Biology Of Hybopsis Amblops, The Bigeye Chub, In The Flint River Of Alabama, Crissy L. Tarver, Bruce W. Stallsmith

Southeastern Fishes Council Proceedings

The purpose of this study was to establish a reproductive schedule and examine reproductive traits that shape fecundity of the Bigeye Chub, Hybopsis amblops Leuciscidae in the Flint River system of north Alabama. Traits associated with reproduction, growth, and maturation were assessed. Specimens were collected and examined monthly from August, 2013 until July, 2014. This Bigeye Chub population primarily spawns in April and May as indicated by gonadosomatic index (GSI), ovarian condition and clutch size. Mean GSI values began to rise in February, peaking in April and May at over 13% for females and 1.6% for males. There was a …


Diet: Another Piece Of The Crime Puzzle?, Jerrod Brown, Jeremiah Schimp, Leanne Skehan, Amanda Fenrich, Janina Cich Jan 2026

Diet: Another Piece Of The Crime Puzzle?, Jerrod Brown, Jeremiah Schimp, Leanne Skehan, Amanda Fenrich, Janina Cich

Nutritional Neurocriminology Today

An expanding body of research suggests that diet and nutrition may play an influential yet underrecognized role in problematic and criminal behaviors. This article synthesizes research linking excessive consumption of sugar and ultra-processed foods to adverse neurobehavioral outcomes, impaired impulse control, aggression, mood dysregulation, and sleep problems. Integrating research suggests that metabolic disruption, neuroinflammation, and gut–brain axis dysfunction may influence cognitive and emotional regulation. While criminal behavior is complex and multifactorial, this article emphasizes nutrition as a modifiable factor to inform forensic mental health practice, correctional policy, and rehabilitative strategies.


Evaluation Of Occupational Health And Safety Knowledge, Attitudes, And Practices Of Workers At North Refineries Company, Wesam Awad Hassn, Zeena N. Abdulrahman Jan 2026

Evaluation Of Occupational Health And Safety Knowledge, Attitudes, And Practices Of Workers At North Refineries Company, Wesam Awad Hassn, Zeena N. Abdulrahman

AUIQ Complementary Biological System

Safety is crucial in the oil and gas refinery industry for production and distribution. Companies must ensure a workplace free from common injuries and protected against serious incidents. This paper evaluates employees’ knowledge, attitudes, practices, and workplace environment at North Refineries Company (Baiji). A descriptive cross-sectional study was conducted from September 10, 2024, to September 20, 2025, involving 480 employees (378 workers and 102 managers). Data were collected through face-to-face interviews and analysed using SPSS version 24. North Refineries Company (Baiji). workers scored 72.49 % on general knowledge and 96.83% on attitudes, but only 53.97% on safe behaviour. Division managers …


Prevention Of Postoperative Nausea And Vomiting In Early Recovery: A Comparative Study Of Ondansetron And Metoclopramide In Adults Undergoing Elective Lower Abdominal Surgery, Majid Fakhir Al-Hamaidah, Ali Ihsan Abdul Mahdi, Maytham Alaa Shahid, Sajjad Salih Rasan, Lina M. Shaker, Shahab Abdulla, Ralela Makline Jan 2026

Prevention Of Postoperative Nausea And Vomiting In Early Recovery: A Comparative Study Of Ondansetron And Metoclopramide In Adults Undergoing Elective Lower Abdominal Surgery, Majid Fakhir Al-Hamaidah, Ali Ihsan Abdul Mahdi, Maytham Alaa Shahid, Sajjad Salih Rasan, Lina M. Shaker, Shahab Abdulla, Ralela Makline

AUIQ Complementary Biological System

Postoperative nausea and vomiting (PONV) remain common complications following surgery, despite the availability of various prophylactic antiemetic agents. This study aimed to compare the effectiveness of ondansetron and metoclopramide in preventing PONV in patients undergoing elective lower abdominal surgery under general anesthesia. In this double-blind, randomized controlled trial, 80 adult patients were equally allocated into two groups: one receiving 0.1 mg/kg of intravenous ondansetron and the other 0.2 mg/kg of intravenous metoclopramide at the end of surgery. The incidence, frequency, and need for rescue antiemetics were evaluated over 24 hours postoperatively. The overall incidence of nausea was higher in the …


More Than A Prescription: The Need For Behavioral Theory To Guide Exercise Interventions For Osteoarthritis - A Narrative Review, Christine Pellegrini, Lisa C. Carlesso, Daniel K. White Jan 2026

More Than A Prescription: The Need For Behavioral Theory To Guide Exercise Interventions For Osteoarthritis - A Narrative Review, Christine Pellegrini, Lisa C. Carlesso, Daniel K. White

Faculty Publications

Objective

Many clinical exercise trials show that participation in exercise, such as strength training and aerobic walking, reduce osteoarthritis (OA)-related pain and functional limitation. This has led to exercise being one of the most commonly prescribed treatments for OA. However, little attention is given to the complex behavior elements of exercise, that is exercise is an activity that adults need to choose to engage in regularly, which is necessary to ensure exercise can have long-term efficacy to address pain. The purpose of this review is to highlight the behavioral aspects of exercise.

Design

Narrative review

Results

Limitations of previous clinical …


Supervised Resistance Training In An Individual With Glioblastoma Undergoing Chemoradiation: A Case Report, Bruce Nakfoor, Ciaran Fairman Ph.D., Cscs, Cet Jan 2026

Supervised Resistance Training In An Individual With Glioblastoma Undergoing Chemoradiation: A Case Report, Bruce Nakfoor, Ciaran Fairman Ph.D., Cscs, Cet

Faculty Publications

Introduction:

Exercise has demonstrated safety and efficacy in mitigating treatment-related symptoms across cancer populations; however, evidence in neuro-oncology remains limited, particularly during active chemoradiation.

Methods:

We report the case of a 63-year-old individual with newly diagnosed glioblastoma, experiencing symptoms of fatigue, balance issues, headaches, and memory loss, who initiated a 12-week supervised resistance training program during concurrent chemoradiation. Assessments at baseline and post-intervention included physical function and quality-of-life outcomes.

Results:

Adherence was 56% (20/36 sessions), and no adverse events occurred. The patient showed improvements in 6-minute walk distance and short physical performance battery score that exceeded established minimal clinically important …


Strength In Numbers: Exploring The Link Between Upper Body Muscular Strength And Academic Achievement In Youth, Julian A. Reed, Marsha Dowda Drph, Russell R. Pate Ph.D. Jan 2026

Strength In Numbers: Exploring The Link Between Upper Body Muscular Strength And Academic Achievement In Youth, Julian A. Reed, Marsha Dowda Drph, Russell R. Pate Ph.D.

Faculty Publications

Objectives

The purpose of this study was to examine the associations between upper body strength and endurance (UMSE) and academic achievement in youth.

Design

Cross-sectional study included 5th (N = 25,025) and 8th grade (N = 14,988) students in South Carolina.

Methods

Academic achievement was measured using a statewide assessment and classified into two categories (meets/exceeds standards or does not meet/approaches standards). Achievement in mathematics and English Language Arts was assessed. UMSE was measured as part of the South Carolina FitnessGram project and expressed as Healthy Fitness Zone (HFZ) or Needs Improvement – Health Risk. Student demographic characteristics were derived …


Cv: Sterling Richards, Sterling Richards Jan 2026

Cv: Sterling Richards, Sterling Richards

Health Sciences Department Curricula Vitae

No abstract provided.


Biology Department Publications: 2025, Sam Lindgren Jan 2026

Biology Department Publications: 2025, Sam Lindgren

Biology Department Bibliographies

This document is a non-comprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2024. It indexes those publications available through PubMed, and serves as an archival record of the Department's robust scholarly contributions.


Dapagliflozin Attenuates Cisplatin-Induced Nephrotoxicity In Rats Through Modulation Of Ros/Nf-Κb, Bcl2/Bax And Pink1/Parkin Signaling Pathways, Esraa K. Khallaf, Eman A. Ramadan, Mohey M. Elmazar, Marwa M. Safar Jan 2026

Dapagliflozin Attenuates Cisplatin-Induced Nephrotoxicity In Rats Through Modulation Of Ros/Nf-Κb, Bcl2/Bax And Pink1/Parkin Signaling Pathways, Esraa K. Khallaf, Eman A. Ramadan, Mohey M. Elmazar, Marwa M. Safar

Pharmacy

Dapagliflozin (DPG), an anti-diabetic drug, has gained attention for its renal protective effects through multiple molecular pathways, yet its impact on mitophagy in cisplatin (CIS) nephrotoxicity remains unclear. This study aimed to examine the impact of DPG against CIS-induced nephrotoxicity in rats, targeting mainly PINK1/Parkin-mediated mitophagy and inflammatory/apoptotic pathways. Male Sprague Dawley rats received DPG (10 mg/kg; p.o) daily for 14 consecutive days and AKI was induced by a single injection of CIS (7 mg/kg; i.p) on day 10. Blood glucose, serum levels of creatinine and urea nitrogen, oxidative stress, inflammatory, apoptotic, mitophagy markers, and histological changes were assessed. DPG …


Dual-Task Effects On Spatiotemporal, Kinematic, And Kinetic Parameters And Their Variability During Running, Hsiang-Ling Teng, Jo Armour Smith, Will F.W. Wu Jan 2026

Dual-Task Effects On Spatiotemporal, Kinematic, And Kinetic Parameters And Their Variability During Running, Hsiang-Ling Teng, Jo Armour Smith, Will F.W. Wu

Physical Therapy Faculty Articles and Research

Background

Running in real-world environments often requires using cognitive resources simultaneously with the motor task (dual tasking, DT). Limited existing evidence suggests that DT reduces running speed. Movement variability is essential for a healthy, adaptable motor system. DT has been shown to affect movement variability during walking. Nonetheless, it remains unclear how DT affects spatiotemporal, kinematic, and kinetic parameters and their variability during running.

Research question

Does DT affect spatiotemporal, kinematic, and kinetic measures and their variability during running? Does running speed influence DT effects?

Methods

Thirty-one asymptomatic runners participated in this cross-sectional study. Three-dimensional running biomechanics were recorded while …


Genome-Wide Association Study Identifies Novel Variants In Olfactory, Vitamin A, Vitamin B, And Cadherin Pathways Associated With Learning And Memory, Lloyd N. Hopkins, Nesli Avgan, Heidi G. Sutherland, Francesca E. Fernandez, Emma M. Knowles, Larisa M. Haupt, John Blangero, David C. Glahn, David H. K. Shum, Rod A. Lea, Lyn R. Griffiths Jan 2026

Genome-Wide Association Study Identifies Novel Variants In Olfactory, Vitamin A, Vitamin B, And Cadherin Pathways Associated With Learning And Memory, Lloyd N. Hopkins, Nesli Avgan, Heidi G. Sutherland, Francesca E. Fernandez, Emma M. Knowles, Larisa M. Haupt, John Blangero, David C. Glahn, David H. K. Shum, Rod A. Lea, Lyn R. Griffiths

Human Genetics Publications

Learning and memory, as fundamental components of human cognition, are heritable traits that are highly variable between individuals and within populations. Investigation into the genetic basis of cognition is a prominent area of research, with genetic associations being previously reported for a wide range of cognitive phenotypes. Here we utilise a genome-wide association study (GWAS) approach to evaluate the contribution of genetic variation to learning and memory phenotypes in a comprehensively phenotyped, well-characterised, healthy, and unrelated cohort of individuals (n = 613). Cognitive phenotypes were assessed using nine comprehensive test batteries consisting of twenty-one cognitive performance assessments including IQ, five …


Simulated Complex Cells Contribute To Object Recognition Through Representational Untangling, Mitchell B Slapik, Harel Z Shouval Jan 2026

Simulated Complex Cells Contribute To Object Recognition Through Representational Untangling, Mitchell B Slapik, Harel Z Shouval

Faculty, Staff and Student Publications

The visual system performs a remarkable feat: it takes complex retinal activation patterns and decodes them for object recognition. This operation, termed "representational untangling," organizes neural representations by clustering similar objects together while separating different categories of objects. While representational untangling is usually associated with higher-order visual areas like the inferior temporal cortex, it remains unclear how the early visual system contributes to this process-whether through highly selective neurons or high-dimensional population codes. This article investigates how a computational model of early vision contributes to representational untangling. Using a computational visual hierarchy and two different data sets consisting of numerals …


Prediction Of Structure And Function Of A Novel Β-Lactamase Protein In Gram-Negative Bacteria Using Homology Modeling And Molecular Docking, Ariyani Kiranasari, Surya Dwira, Engla Merizka Jan 2026

Prediction Of Structure And Function Of A Novel Β-Lactamase Protein In Gram-Negative Bacteria Using Homology Modeling And Molecular Docking, Ariyani Kiranasari, Surya Dwira, Engla Merizka

Indonesian Journal of Medical Chemistry and Bioinformatics

The emergence of β-lactamase–producing Gram-negative bacteria represents a major global challenge due to increasing resistance to β-lactam antibiotics. In this study, we performed in silico structural and functional prediction of a newly identified β-lactamase protein sequence obtained from a Gram-negative bacterial isolate. Homology modeling was used to construct a reliable 3D model of the protein based on structurally resolved β-lactamases. The model was further evaluated using stereochemical validation parameters. Molecular docking was conducted to assess binding affinity and interaction patterns between the predicted β-lactamase and clinically relevant β-lactam antibiotics, including ampicillin, cefotaxime, and imipenem. The results revealed conserved catalytic residues …


Innovative Applications And Development Paths Of Digital Earth Technology In Marine Environmental Support, Junyi Liu, Xiongfei Liu, Zongji Wang, Zhihong Zeng, Huiping Xie, Siye Liu Jan 2026

Innovative Applications And Development Paths Of Digital Earth Technology In Marine Environmental Support, Junyi Liu, Xiongfei Liu, Zongji Wang, Zhihong Zeng, Huiping Xie, Siye Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The convergence of Digital Earth technologies and the field of marine environmental support represent a significant trend in global scientific and technological advancement. In response to the characteristics of marine environmental data such as sparsity, dynamic complexity, and multi-scale interdependence, and by integrating the evolution of international Digital Earth technology with China’s independent innovation practices, this study constructs three core methodological paradigms. The first is the element-integrated ontology, which proposes a hybrid representation paradigm of “spatiotemporal embedded field + ontology” to achieve integrated and dynamically evolving modeling of marine physical environments alongside geological, biological, chemical, and other multidimensional elements. The …


Thoughts On Accelerating The Capture Of Technological High Ground For Precise Marine Environmental Assurance, Yuantao Wu, Mingyue Wan, Deke Chen, Danhong Dong, Yao Yu, Miao Chen Jan 2026

Thoughts On Accelerating The Capture Of Technological High Ground For Precise Marine Environmental Assurance, Yuantao Wu, Mingyue Wan, Deke Chen, Danhong Dong, Yao Yu, Miao Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

The marine environment serves as a critical foundation for the development, utilization, protection, and governance of the ocean. Marine environmental support holds significant strategic importance for the exploitation of marine resources, ecological and environmental conservation, and the safeguarding of maritime rights and interests. It has become a strategic high ground in the new wave of marine technological innovation and development. This paper reviews the current status of global marine environmental support technologies, with a focus on the establishment and capabilities of the comprehensive “observation–forecasting–application–assessment” precision support technology system for the marine environment developed by the Chinese Academy of Sciences. It …


Frontiers In Ocean Non-Equilibrium Dynamics And Challenges In Operational Oceanography Application, Yuhong Zhang, Yan Du, Tianyu Wang, Minyang Wang, Qin Duan, Xinlong Li, Yuhang Zheng, Yifan Xia, Shilin Tang, Yineng Li, Jianping Yin Jan 2026

Frontiers In Ocean Non-Equilibrium Dynamics And Challenges In Operational Oceanography Application, Yuhong Zhang, Yan Du, Tianyu Wang, Minyang Wang, Qin Duan, Xinlong Li, Yuhang Zheng, Yifan Xia, Shilin Tang, Yineng Li, Jianping Yin

Bulletin of Chinese Academy of Sciences (Chinese Version)

Ocean circulation exhibits complex multiscale dynamics, among which non-equilibrium processes, marked by transient behavior, strong perturbations, and pronounced nonlinearity, are of particular importance for maritime environmental support. However, limited observational capability has long constrained the study of subsurface non-equilibrium dynamics, leaving numerical models insufficiently validated and positioning this issue at the forefront of modern physical oceanography. Artificial intelligence (AI) offers a promising pathway to overcome this bottleneck. Built on this concept, the “iEddy” AI large ocean model can efficiently reconstruct high-resolution, high-accuracy three-dimensional temperature, salinity, and velocity from sea-surface remote sensing data, demonstrating strong capability in capturing non-equilibrium ocean currents …


Current Status And Prospects Of Ocean Data Reanalysis, Chuanyu Liu, Fan Wang Jan 2026

Current Status And Prospects Of Ocean Data Reanalysis, Chuanyu Liu, Fan Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Ocean data reanalysis (ODR) is a technique that combines ocean observational data with ocean circulation models to produce gridded data with higher accuracy and greater spatiotemporal coverage. The generated reanalysis data serve as a foundational dataset for conducting oceanographic research and developing artificial intelligence-based large ocean models. This study reviews the technical approaches of ODR, the current status of global and regional ocean data reanalysis systems developed in the world, and puts forward recommendations for the development of China's ocean reanalysis system.


Development Trends And Implications Of Muti-Objective Marine Environmental Forecasting Technology, Yineng Li, Yuhang Zhu, Shiqiu Peng, Zhiwu Chen, Xing Wei, Junmin Li, Shaodian Li, Peiwei Xie, Jiawen Liao, Yankun Gong, Shilin Tang, Shuqun Cai Jan 2026

Development Trends And Implications Of Muti-Objective Marine Environmental Forecasting Technology, Yineng Li, Yuhang Zhu, Shiqiu Peng, Zhiwu Chen, Xing Wei, Junmin Li, Shaodian Li, Peiwei Xie, Jiawen Liao, Yankun Gong, Shilin Tang, Shuqun Cai

Bulletin of Chinese Academy of Sciences (Chinese Version)

With the continuous expansion of global maritime activities and the steady advancement of the “maritime power” strategy, marine environmental security has become a top priority for China. In deep-sea areas, various environmental parameters such as temperature, salinity, sound velocity, wave dynamics, internal solitary waves, and nearshore rip currents play a crucial role in navigation safety and underwater equipment operations. Nevertheless, traditional single-parameter forecasting models are no longer sufficient to meet the demands of multi-objective environmental protection. As a result, there is a growing need for a high-resolution, multi-objective forecasting system that integrates basic oceanographic element predictions (such as temperature, salinity, …


Transparent West-Pacific: Frontier Advances In Earth System Science, Lixin Wu, Jiwei Tian, Weidong Sun, Hailong Liu, Tianyu Chen, Zhimian Cao, Zhao Jing Jan 2026

Transparent West-Pacific: Frontier Advances In Earth System Science, Lixin Wu, Jiwei Tian, Weidong Sun, Hailong Liu, Tianyu Chen, Zhimian Cao, Zhao Jing

Bulletin of Chinese Academy of Sciences (Chinese Version)

The West-Pacific hosts a well-developed trench-arc-basin system characterized by intense fluid–solid interactions, making it an ideal region for studying multi-sphere interactions within the Earth system. Research on cross-sphere dynamic processes and material-energy cycles in the West-Pacific not only represents a core frontier in Earth System Science, but also crucial to addressing major strategic needs, such as global climate change response, sustainable use of marine resources, and protection of the deep-sea environment. This article highlights key advances achieved under the Major Program on West-Pacific Earth System Multispheric Interactions (WESPMI), in areas including multi-scale oceanic interactions, cross-sphere material exchange, plate subduction and …


Satellite-Derived Bathymetry In Island Coastal Zones: Technology, Shilin Tang, Yuye Huang, Yongming Liu, Jianping Yin, Deke Chen, Ronggang Huang, Shuang Li Jan 2026

Satellite-Derived Bathymetry In Island Coastal Zones: Technology, Shilin Tang, Yuye Huang, Yongming Liu, Jianping Yin, Deke Chen, Ronggang Huang, Shuang Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

Shallow bathymetry data constitute the core foundational information underpinning the ecological, resource, and strategic values of island and coastal zones. Satellite-derived bathymetry has evolved into a key technical means for large-scale acquisition of shallow bathymetry information. Focusing on satellite-based lidar bathymetry, optical imaging bathymetry, and synthetic aperture radar (SAR) bathymetry, this study systematically summarizes the core principles, applicable scenarios, technical strengths, and inherent limitations of each technology. It is shown that satellite-derived bathymetry has undergone an evolutionary shift from theoretical construction to practical application, and from single-method, single-data-source approaches to multi-technology, multi-source data fusion frameworks. In the future, to meet …


Genomics Define Malignant Transformation In Myeloma Precursor Conditions, Francesco Maura, P Leif Bergsagel, Bachisio Ziccheddu, Shaji Kumar, Kylee Maclachlan, Andriy Derkach, Juan-Jose Garces, Ross Firestone, Esteban Braggio, Yan Asmann, Michael Durante, Benjamin T Diamond, Marios Papadimitriou, Malin Hultcrantz, Alessio Marella, Giancarlo Castellano, Akihiro Maeda, Marta Lionetti, Antonio Matera, Stefania Pioggia, Matteo Claudio Da Vià, Claudio De Magistris, Daniel Leongamornlert, Danny Deavila, Praneeth Reddy Sudalagunta, Rafael Renatino Canevarolo, Erin M Siegel, Phaedra Agius, Jamie Teer, Andrew Mcpherson, Yusuke Yamashita, Ariosto S Silva, Patrick Blaney, Rachid Baz, Krina K Patel, Peter Campbell, Gareth Morgan, Rafael Fonseca, Ola Landgren, Robert Z Orlowski, Kenneth H Shain, Niccolo Bolli, Saad Usmani, S Vincent Rajkumar Jan 2026

Genomics Define Malignant Transformation In Myeloma Precursor Conditions, Francesco Maura, P Leif Bergsagel, Bachisio Ziccheddu, Shaji Kumar, Kylee Maclachlan, Andriy Derkach, Juan-Jose Garces, Ross Firestone, Esteban Braggio, Yan Asmann, Michael Durante, Benjamin T Diamond, Marios Papadimitriou, Malin Hultcrantz, Alessio Marella, Giancarlo Castellano, Akihiro Maeda, Marta Lionetti, Antonio Matera, Stefania Pioggia, Matteo Claudio Da Vià, Claudio De Magistris, Daniel Leongamornlert, Danny Deavila, Praneeth Reddy Sudalagunta, Rafael Renatino Canevarolo, Erin M Siegel, Phaedra Agius, Jamie Teer, Andrew Mcpherson, Yusuke Yamashita, Ariosto S Silva, Patrick Blaney, Rachid Baz, Krina K Patel, Peter Campbell, Gareth Morgan, Rafael Fonseca, Ola Landgren, Robert Z Orlowski, Kenneth H Shain, Niccolo Bolli, Saad Usmani, S Vincent Rajkumar

Faculty, Staff and Student Publications

Multiple myeloma (MM) is consistently preceded by monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). While these precursor conditions are asymptomatic, they are not entirely benign and carry a lifelong risk of progression to MM. Unlike other cancers defined by pathology, malignant transformation from MGUS or SMM to MM has so far relied on demonstration of clinical end-organ damage as morphology and cytogenetics cannot reliably distinguish them. In this study, using genomic data from 374 patients with MGUS or SMM (277 training, 97 validation), to our knowledge, we demonstrate for the first time the ability to identify …


The Influence Of Bapineuzumab And Semagacestat On Rapid Progressors: A Retrospective Cohort Study, Kristofer Harris, Madison Shyer, Dulin Wang, Elizabeth He, Matias Cattani, Catherine Zhang, Christine M Farrell, Xiaoqian Jiang, Yejin Kim, Paul E Schulz Jan 2026

The Influence Of Bapineuzumab And Semagacestat On Rapid Progressors: A Retrospective Cohort Study, Kristofer Harris, Madison Shyer, Dulin Wang, Elizabeth He, Matias Cattani, Catherine Zhang, Christine M Farrell, Xiaoqian Jiang, Yejin Kim, Paul E Schulz

Faculty, Staff and Student Publications

Background: A subset of Alzheimer's disease patients progresses much more rapidly than average. These rapid progressors exhibit accelerated cognitive and functional decline. Potential differences in Alzheimer's biomarkers for rapid progressors and their responses to disease-modifying treatments remain poorly understood, with previous clinical trials and studies producing limited biomarker data and inconsistent results.

Objectives: Examine differences in rapid progressor versus non-rapid progressor outcomes in two AD treatment trials (bapineuzumab and semagacestat) and investigate cognitive and biomarker progression in the placebo groups.

Design: Retrospective cohort study.

Setting: Four randomized, double-blind, phase 3 clinical trials from the Center for Global Clinical Research Data …


Optimal Drought Management Actions For Cattle Operations On The Uintah And Ouray Indian Reservation, Kynda R. Curtis, Tatiana Drugova, Man-Keun Kim Jan 2026

Optimal Drought Management Actions For Cattle Operations On The Uintah And Ouray Indian Reservation, Kynda R. Curtis, Tatiana Drugova, Man-Keun Kim

All Current Publications

In this fact sheet, we examine the drought management options available to cattle operations on the Uintah and Ouray Reservation, the largest Native American reservation in Utah. Specifically, we discuss the results of a study that evaluated the economic outcomes of two common drought response strategies: herd reduction and supplemental hay purchases. We also provide recommendations for ranchers on optimal strategies, i.e., those that maximize profits for two rancher types, differentiated by their willingness to accept risk (risk-neutral) or avoid it (risk-averse).


Optimal Drought Management Actions For Cattle Operations On The Laguna Pueblo And Zuni Pueblo Indian Reservations, Tatiana Drugova, Kynda R. Curtis, Man-Keun Kim Jan 2026

Optimal Drought Management Actions For Cattle Operations On The Laguna Pueblo And Zuni Pueblo Indian Reservations, Tatiana Drugova, Kynda R. Curtis, Man-Keun Kim

All Current Publications

In this fact sheet, we examine the drought management options available to cattle operations on the Laguna Pueblo and Zuni Pueblo reservations in New Mexico. Specifically, we discuss the results of a study that evaluated the economic outcomes of two common drought response strategies: herd reduction and supplemental hay purchases. We also provide recommendations for ranchers regarding optimal strategies, i.e., those which would maximize profits, for two rancher types, differentiated by their willingness to accept risk (risk-neutral) or avoid it (risk-averse).


Optimal Drought Management Actions For Cattle Operations On The Duck Valley And Pyramid Lake Indian Reservations, Kynda R. Curtis, Tatiana Drugova, Man-Keun Kim Jan 2026

Optimal Drought Management Actions For Cattle Operations On The Duck Valley And Pyramid Lake Indian Reservations, Kynda R. Curtis, Tatiana Drugova, Man-Keun Kim

All Current Publications

In this fact sheet, we examine the drought management options available to cattle operations on two Native American reservations in Nevada, the Duck Valley and Pyramid Lake Indian reservations. Specifically, we discuss the results of a study that evaluated the economic outcomes of two common drought response strategies: herd reduction and supplemental hay purchases. We also provide recommendations for ranchers regarding optimal strategies, i.e., those which would maximize profits for two rancher types, differentiated by their willingness to accept risk (risk-neutral) or avoid it (risk-averse).


Biostimulant Applications In Watermelon Production, Evan A. Christensen, Milena Oliveira, Youping Sun, Grant Cardon, Dan Drost Jan 2026

Biostimulant Applications In Watermelon Production, Evan A. Christensen, Milena Oliveira, Youping Sun, Grant Cardon, Dan Drost

All Current Publications

Watermelon is a water-intensive vegetable crop that is sensitive to drought and requires adequate nutrient supply for good yield and fruit quality. It is an important vegetable crop grown on 142,000 acres in the United States and 586 acres throughout Utah. Utah experienced its driest year on record in 2020 during a five-year drought (2019 to 2023). This affected local ecosystems, including the Great Salt Lake, which experienced record-low water levels. The drought also negatively affected the agricultural sector, including watermelon growers. Higher-than-average fertilizer prices in recent years have also threatened watermelon production. Growing awareness of agriculture's water use and …


Biopcm-Integrated Smart Façade For Hospitals: Thermal Performance Across Floor Levels In A Hot-Arid Climate, Aia A. Qindil, Esraa Elazab, Mohamed M. Shawky Abou Liela Jan 2026

Biopcm-Integrated Smart Façade For Hospitals: Thermal Performance Across Floor Levels In A Hot-Arid Climate, Aia A. Qindil, Esraa Elazab, Mohamed M. Shawky Abou Liela

Mansoura Engineering Journal

Hospitals are among the most energy-intensive building types because they operate around the clock and must maintain strict indoor environmental conditions, especially in hot-arid climates. Improving their performance calls for façade solutions that can store thermal energy effectively and help cut carbon emissions. This study evaluates the use of macro-encapsulated BioPCM® within the south façade of a high-rise hospital in Mansoura, Egypt, using dynamic simulations in DesignBuilder (EnergyPlus). The analysis focuses on two vertical levels, the third floor as a typical ward and the seventh floor as a rooftop ward, to investigate how elevation influences PCM performance, an aspect rarely …


Credit Card Fraud Detection Using Metaheuristic Techniques, Narges Sabry Anwer Mohammed, Mohammed Sabry Saraya, Amr M. Thabet, Labib M. Labib Jan 2026

Credit Card Fraud Detection Using Metaheuristic Techniques, Narges Sabry Anwer Mohammed, Mohammed Sabry Saraya, Amr M. Thabet, Labib M. Labib

Mansoura Engineering Journal

Credit Card Fraud Detection (CCFD) has become a critical challenge to financial security due to increasingly sophisticated fraudulent activities. This study investigates the effectiveness of Meta-Heuristic (MHT) optimization techniques in improving fraud detection (FD) through feature selection (FS) and model optimization. To address class imbalance, Random Under-Sampling (RUS) was applied. The selected feature subsets were evaluated using three machine learning (ML) classifiers—Decision Tree (DT), KNearest Neighbours (KNN), and XGBoost (Xgb-Tree)—across four benchmark datasets: European, Statlog (Australian Credit Approval), PaySim, and Credit Card Transactions Fraud Detection (CCTFD). Eleven binary MHT algorithms were implemented and compared. The comparative analysis shows that the …


Table Of Contents Jan 2026

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.