Digital Commons Network^™

Agricultural Water Leasing Opportunities & Updates, Hannah Freeze

Spring Runoff Conference

The framework for this leasing program is based on depletion savings from conservation practices not surplus or tailwater

Pheasant Forever Loan Program, Will Benkelman

Spring Runoff Conference

Bear River Watershed Community Conservation Program

Our Mission: Pheasants Forever (PF) and Quail Forever’s (QF) mission is to conserve pheasants, quail, and other wildlife through habitat improvements, public access, education, and conservation advocacy.

Logan River Watershed Draft Environmental Impact Statement, Zan Murray

Spring Runoff Conference

Agenda:

Program Overview: PL-566 & NEPA

Project Need and Purpose

Project Alternatives

Preferred Alternative Costs and Benefits

NEPA Timeline/Current Schedule

Questions

Cache Water District Conservation Program, Autumn Matthews

Spring Runoff Conference

Conservation and Education Programs.

Conservation Goals:

Increase community awareness through outreach, workshops, and community programs that support water conservation.

Expand and improve programs that encourage water savings and more efficient water use across the community.

Help residents save money by promoting water efficiency and reducing unnecessary water use.

Water Supply Update, Jordan Clayton

Spring Runoff Conference

Snowpack and Water Supply Conditions.

>95% of the water we use in Northern Utah comes from snow. Therefore, it’s critically important to quantify how much water is stored in our snowpack.

Legislative Summary Panel, Brian Steed, Scott Sandall, Jill Koford, Joel Ferry

Spring Runoff Conference

Legislative updates provided at the Spring Runoff Conference 2026.

Water In 2026, Spencer Cox

Spring Runoff Conference

Presentation by Utah Governor Cox.

Mitochondrial Transfer And Induced Ros As A Therapeutic Strategy In Idh2-Mutant Chondrosarcoma, Vegas R. Bedder, Caleb Wyckoff, Chris Osgood, Gavin A. Vasquez, Michael Stacey

Knowledge and Creativity Expo

Chondrosarcoma (CS) are common bone cancers that produce cartilaginous tumors and are extremely refractive to chemo-and-radiation therapies, leaving very limited treatment options. They contain mutations in the isocitrate dehydrogenase genes, IDH1 or IDH2. Either IDH1 or IDH2 mutations are present in individual tumors, but not both. They both convert alphaketoglutarate (αKG) into the potent oncometabolite D-2-hydroxyglutarate (D2HG). D2HG can be transported from the tumors to cells of the tumor microenvironment (TME) where it can alter metabolic and epigenetic profiles in recipient cells. The process of α-KG to D2HG conversion occurs in the cytoplasm of IDH1 mutant cells, and in the …

Recombinant Hagfish Intermediate Filament Proteins Enable Neural Culture Substrates That Promote Neurite Extension And Reduce Oxidative Stress, Justin Jones, Kristin Durrant

Browse all Datasets

This dataset supports the production, characterization, and biological validation of a novel recombinant hagfish intermediate filament (rHIF) protein functionalized with spider silk motifs (rHIF-alpha-GRGGL). The data demonstrates a scalable bioprocess resulting in a 7.76 g/L yield, high structural alpha-helicity (77.2%), and significant support for N2a cells.

Bacillus Subtilis Parb C-Terminal Lysine Residues Are Essential For Dimerization And In Vivo Function, Indicating Their Roles In Dna Sliding, Aleksey Aleshintsev, Lindsey E. Way, Ngoc Khanh Lai, Bianca Guerra, Paloma Dorantes, Lois Akosua Serwaa, Sealtiel Anulao, Miranda Molina, Xindan Wang, Hyeongjun Kim

Physics & Astronomy Faculty Publications

The broadly conserved ParB protein performs crucial functions in bacterial chromosome segregation and replication regulation. The cellular function of ParB requires it to dimerize, recognize parS DNA sequences, clamp on DNA, then slide to adjacent sequences through nonspecific DNA binding. How ParB coordinates nonspecific DNA binding and sliding remains elusive. Here, we combine multiple in vitro biophysical and computational tools and in vivo approaches to address this question. We found that five conserved lysine residues in the C-terminal domain (CTD) of ParB play distinct roles. While the two central rigid lysine residues provide the structural platform for the CTD, the …

Nexus Of Food Security Versus Armed Conflict In The Context Of Climate Change In Mali, Moussa Macalou, Youssouf Diabate, Abdoulaye Nientao, Adama B. Coulibaly

Professional Agricultural Workers Journal

The nexus between food security and armed conflict, with particular focus on developing countries, has been analyzed by a few studies in the literature. Every country under armed conflict is obligated to solve related food security issues. Therefore, the overall objective of this study was to analyze the nexus between households’ food security and armed conflicts in the context of climate change in Mali. To achieve this objective, first, the study used an ordinary least squares model to determine the factors influencing households’ food security. Second, it used an ordered logit model to determine the factors influencing armed conflict. Apart …

Artificial Intelligence In Mycology: A Systematic Review Of Species Identification, Biotechnological Assessment, And Explainable Deep Learning Methods, Fati̇h Eki̇nci̇, Mehmet Serdar Güzel, Ilgaz Akata

Turkish Journal of Botany

This review offers a comprehensive analysis of the expanding role of artificial intelligence (AI) in mycological research. It highlights how AI supports the identification of fungal taxa at both microscopic and macroscopic levels, facilitates the detection of toxic species, contributes to ecological mapping, aids in discovering new fungal bioproducts, and enhances precision agriculture practices. Advanced techniques such as convolutional neural networks, you only look once, U-shaped network (UNet), and residual network have demonstrated strong performance in classification, segmentation, and object detection tasks. Additionally, explainable AI (XAI) methods like gradient-weighted class activation mapping (Grad-CAM), local interpretable model-agnostic explanations (LIME), and SHapley …

Global Transcriptomic Insights Into Nla-Dependent Boron Toxicity Responses In Arabidopsis Thaliana, Doğa Seli̇n Kayihan

Turkish Journal of Botany

Boron (B) toxicity disrupts multiple metabolic and signaling processes in plants, yet its interaction with post-translational regulators remains poorly understood. The E3 ubiquitin ligase NITROGEN LIMITATION ADAPTATION (NLA) is known to control nutrient transporter turnover, but its role in B toxicity responses has not been previously characterized. Here, we present the first genome-wide transcriptomic analysis of nla mutant Arabidopsis thaliana exposed to mild (1 mM) and moderate (2 mM) B toxicity. Loss of NLA caused a profound reprogramming of gene expression, marked by constitutive activation of ribosome- and translation-related pathways and strong repression of MAPK signaling, α-linolenic acid metabolism, and …

Ethnobotanical Study Of Medicinal Plants Used By The Local Population In And Around Kozak Plateau (Bergama, İzmir, Türkiye), Şükrü Arasan, Hasan Yildirim

Turkish Journal of Botany

This research was conducted between 2020 and 2022 in 21 villages located on the Kozak Plateau and its surroundings, in the Bergama district of İzmir province, Türkiye. The main aim of the study is to document the medicinal uses of plants by the local population and to contribute to the preservation and transmission of ethnobotanical knowledge—passed down through generations— to future generations before it disappears. Interviews were conducted with 159 informants, and the traditional medicinal uses of 126 plant taxa belonging to 54 families were identified. Among these, the therapeutic uses of 37 taxa were recorded for the first time. …

Insights Into The Role Of Sox6 In The Developing Heart, Hannah Tarolli

MUSC Theses and Dissertations

Approximately 40,000 babies born each year in the U.S. have a congenital heart defect (CHD). However, only a small percentage of CHDs has a known genetic cause, highlighting the need for research surrounding heart development and the pathogenesis of CHDs. Heart development research aims to elucidate the precise coordination of gene expression and cell signaling with the goal of advancing prevention and treatment methods. During heart development, cells from several origins play a crucial role. This includes cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field. Previous studies have revealed that the transcription factor, SOX9, is …

Determination Of High-Temperature Stress Tolerance In Strawberry Varieties Based On Physiological And Biochemical Mechanisms, Izhar Ullah, Hüsnü Demi̇rsoy, Musa Kavas, Kubi̇lay Yildirim, Leyla Demi̇rsoy

Turkish Journal of Botany

Rising global temperatures due to climate change threaten optimal strawberry growth and sustainable yields. Limited data exist on the physiological and biochemical responses of strawberry cultivars to high-temperature stress and their tolerance mechanisms. T his study evaluated the responses of 21 day-neutral and short-day strawberry cultivars to high-temperature stress and classified their tolerance levels using a novel weighted rating method. Plants were grown in 15-cm plastic pots (3:1:1 garden soil, peat, perlite) under open-field conditions until the 3–4 leaf stage and then transferred to climate chambers. After acclimatization at 25/15 °C (day/night) for 2 weeks, the plants were subjected to …

Functional Trait Structure In A Plant Community In Central Anatolian Steppe, Cansu Ülgen, Zeynep Ladi̇n Coşgun, Bariş Özüdoğru, Çağatay Tavşanoğlu

Turkish Journal of Botany

Exploring the trait structure of grassland plant communities enhances our understanding of how these communities will respond to climate change and disturbances such as herbivory. The trait structure of a plant community was investigated in the Central Anatolian steppe, an ecoregion with high biodiversity that has been largely unexplored in terms of plant functional ecology. Fifty plant species in the community were measured across 9 plant traits, including several leaf traits (leaf area, leaf dry matter content, specific leaf area, leaf thickness, and leaf nitrogen content), two seed traits (seed mass and seed shape), as well as the plant height …

Advancing The Alabama Black Belt Food Corridor: A Stakeholder-Driven Approach Through The Alabama Black Belt Food Systems Alliance, Kristin Woods, Tana Shealey

Professional Agricultural Workers Journal

A convergence of factors led to the need to bring together a diverse group of stakeholders to empower small-scale farmers in the Alabama Black Belt Region to safely scale up operations and access new markets. In the aftermath of the COVID-19 pandemic, there is renewed interest from government, producers, and consumers in strengthening local and regional food systems. This has led to a greater number of wholesale and retail market opportunities for farmers in the region. A newly formed Alabama Black Belt Food Systems Alliance (ABBFSA) endeavored to gather stakeholders to advance the Black Belt Food Corridor (BBFC) food system. …

Environmental Inequities In Conservation Policies And Practices: A Brief Overview, Monyai Chavers

Professional Agricultural Workers Journal

Conservation science and practice mirror racist notions of colonialism, prolonging a cycle in which policies and programs disregard land access. Many conservation leaders operate from a culture of land exclusion, focusing on nature to generate wealth, deeming the number of individuals removed from the commons as progress. By the turn of the 21^st Century, government conservation policies compensated private actors and groups for voluntarily adopting market-based mechanisms aimed at land conservation. Despite the emergence of various conservation programs, the data show that White Americans primarily benefit from federal conservation payments. However, the fragmentation of Black land ownership allows the …

Comparison Of Heavy Metal Accumulation In Soil And Wood Core Within Tallassee And Tuskegee, Alabama, Alicia R. Wilson, Brianna Smith, Latricia Miller, Rashidah Farid

Professional Agricultural Workers Journal

Heavy metals are natural components of the environment and can be relatively non-impactful in low concentrations. However, high concentrations of heavy metal toxicity can result in air, water, and soil contamination that adversely impacts environmental, human, and wildlife health. This study focuses on detecting the presence of heavy metals in soil, Loblolly Pine tree bark, and wood core samples from sites near a landfill in the Tallassee, Alabama, community and a post-agricultural site in Tuskegee, Alabama. It has been hypothesized that heavy metals are present in soil, tree bark, and the tree’s wood core from sampling sites. Samples were taken …

Impact Of In-Depth Adoption Of System Of Rice Intensification On Food Security Of Smallholder Farm Households In Mali, Moussa Macalou, John Baptist D. Jatoe

Professional Agricultural Workers Journal

The system of rice intensification (SRI) was implemented in Mali to boost rice productivity. The objectives of this paper are to identify the constraints faced by SRI adopters, estimate the food security index, and assess the impact of in-depth adoption of SRI on smallholder farm households’ food security. The study uses Kendall’s ranking to rank the six main constraints identified from the literature. The study uses the Household Food Insecurity Access Scale to estimate households’ food security index. Using primary data collected on rice farm households, the study combines the multivalued treatment effect inverse probability weighted regression adjustment and the …

Evaluation Of Two Varieties Of Okra (Abelmoschus Esculentus (L. Moench) Growth In A Wiregrass Tunnel House And Field, James E. Currington Sr, Victor Khan, Billie Grant, George X. Hunter, Raymon Shange, Cassandra Searight, Edward Sparks, Jeffery Moore, James E. Currington Iii

Professional Agricultural Workers Journal

“Clemson Spineless” and “Jambalaya” okra were grown in a Tunnel House and field to compare yield and other growth parameters. A split-plot design with three replications/treatment was used; the Tunnel House and field were main plots, and varieties split plot. Plant height was significantly taller, and pod harvesting began two weeks earlier in the Tunnel House. Yield showed no significant differences between varieties, and Tunnel House vs. field-produced okra. However, “Clemson Spineless” produced 9% higher pod yield in the Tunnel House than “Jambalaya,” which had 23% higher field yield than “Clemson Spineless.” An enterprise budget analysis showed that Tunnel House …

Abridged Submission Guidelines

Professional Agricultural Workers Journal

No abstract provided.

Novelties In The Genus Aethionema (Brassicaceae) In Türkiye: Resurrections, New Combinations And Status, And New Synonyms, Kuddi̇si̇ Ertuğrul, Tuna Uysal, Hakki Demi̇relma, Emrah Şi̇ri̇n, Meryem Bozkurt, Burcu Yilmaz Çitak

Turkish Journal of Botany

The genus Aethionema in Türkiye was investigated through a comprehensive taxonomic study including morphological, seed micromorphological, and molecular methods. This study led to the synonymization of 11 taxa: A. annuum, A. dincii subsp. baytopiae, A. alidaghenicum, A. bingoelicum, A. dumelicum, A. ertughrulii, A. fruticulosum, A. gypsicola, A. huber-morathii, A. maraschicum, and A. turanicum. Conversely, seven species were resurrected: A. levandowskyi, A. sintenisii, A. acarii, A. pallidiflorum, A. pseudoarmenum, A. pulchellum, and A. recurvum. Four new combinations and status changes (comb. et stat. nov.) were proposed. Reevaluation of synonymous species resulted in the reclassification of A. cardiophyllum and A. lacerum as …

Synthetic Lethality Between Rb-Loss And E2f3 Inhibition In Small Cell Cancers Targeted By Pyrimidine Synthesis Blockade, Evan R. Abt, Liang Wang, Grigor Varuzhanyan, Jack Freeland, Tian He, Guadalupe M. Peña-Garcia, Lauryn Ruegg, Jami Mclaughlin, Donghui Cheng, Nikolas G. Balanis, Chia-Chun Chen, Yang Xu, Yi Xing, Sanaz Memarzadeh, Caius G. Radu, Thomas G. Graeber, Owen N. Witte

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Small cell carcinoma is a highly lethal cancer variant often found with neuroendocrine (NE) features, as exemplified by small cell lung cancer and small cell NE prostate cancer (SCPC). A genome-wide CRISPR dependency screen using SCPC models generated through human prostate cell transformation identifies a requirement for the transcription factor E2F3. E2F3 dependency is linked to RB inactivation, a near universal occurrence across small cell cancers. The requirement for E2F3 is shared by RB-deficient cells originating from the prostate, lung, and adnexa. In RB-deficient cancer cells, E2F3 inhibition restrains cell cycle progression, proliferation, and tumor growth in vivo. Inhibition of …

Transcriptome Profiling Of Silique Lncrnas Reveals Novel Insights Into Silique Length In Radish (Raphanus Sativus L.), Xiaomin Yu, Yuxin Zhu, Zhoubo Guan, Shisheng Li

Turkish Journal of Botany

Radish is a widely cultivated vegetable with known medicinal value and produces siliques that differ significantly in number and size. The present study compares normal Duanye-13 radish (CK-type) siliques with mutant radish siliques induced by chemical mutagenesis at the young (YS), short (SS), and long (LS) silique stages. Differences in long noncoding ribonucleic acid (lncRNA) expression were investigated using high-throughput RNA sequencing and bioinformatic analyses, revealing 45 324 new lncRNAs in radish siliques. lncRNA expression was higher in YS and LS mutant lines than in CK-type lines, and expression in SS mutants tended to be lower than in CK-type lines. …

Fecal Carbohydrate-Degrading Bacteria Are Associated With Reduced Incidence Of Lower Gastrointestinal Gvhd, Christopher Fan, Tomo Hayase, Chia-Chi Chang, Israel K Glover, Ivonne I Flores, Lauren K Mcdaniel, Miriam R Ortega, Christopher A Sanchez, Rawan K El-Himri, Alexandria N Brown, Jennifer L Karmouch, Mohamed A Jamal, Saira S Ahmed, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Ashish Damania, Nadim J Ajami, Jennifer A Wargo, Christine B Peterson, Gabriela Rondon, Taha Al-Juhaishi, Amin M Alousi, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Eric Martens, Cesar A Arias, Robert R Jenq, Eiko Hayase

Faculty, Staff and Student Publications

Lower gastrointestinal graft-versus-host disease (LGI-GVHD) carries morbidity and mortality for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), with critical contributions from the intestinal microbiome. In a retrospective cohort of metagenomic sequencing of stool from patients with allo-HSCT (N = 90), we found that a reduction in specific Parabacteroides and Bacteroides species around the time of engraftment contributes to LGI-GVHD risk. Given the known diverse carbohydrate-degrading functionality of these bacteria, we investigated gene abundances for carbohydrate-active enzymes (CAZymes) and found that Parabacteroides merdae, P distasonis, and Bacteroides ovatus abundances were significantly correlated with CAZymes in patients who did not develop …

Genome-Wide Crispr Screen Identifies A Cytokine-Enhancer Circuit Driving Hif-2Α Activation In Renal Cancer, Jun Fang, Jeremy M Simon, Tao Wang, Yunpeng Gao, Xianju Bi, Lianxin Hu, Chengheng Liao, Cheng Zhang, Yayoi Adachi, Jin Zhou, Hongyi Liu, Qian Liang, James A Nathan, Ram Mani, James Brugarolas, Qing Zhang

Faculty, Staff and Student Publications

Resistance to HIF-2α inhibitors such as Belzutifan underscores the need to better understand how HIF-2α is transcriptionally regulated in clear cell renal cell carcinoma (ccRCC). Here, we uncover a cytokine-driven enhancer mechanism that sustains HIF-2α expression through the JAK1-STAT3 signaling pathway. Using a genome-wide CRISPR screen in VHL-deficient ccRCC cells, we identified SOCS3 as a key negative regulator of HIF-2α. Mechanistically, loss of SOCS3 activates JAK1-STAT3 signaling, leading to the recruitment of STAT3 to distal enhancers upstream of EPAS1 that physically loop to its promoter to drive HIF-2α transcription. This cytokine-enhancer circuit was recapitulated in ccRCC patient samples and functionally …

The Do-It-Yourself Guide To Backyard Drip Irrigation, Jaydee Gunnell, Taun Beddes, Burdette Barker

All Current Publications

This guide promotes efficient backyard drip irrigation as a vital strategy for water conservation in Utah, the third-driest state in the U.S. It explains evapotranspiration (ET), drip system components, and provides formulas to calculate a plant’s water needs. The guide provides practical advice on converting traditional irrigation systems to drip systems, particularly in flower beds and around shrubs and trees. By implementing drip irrigation, homeowners can contribute to water conservation while enhancing the health of their landscapes.

Design Of Experiments Based Reversed-Phase High-Performance Liquid Chromatography Method For Estimation Of Metformin And Glimepiride In Combined Dosage Forms, Neela Manish Bhatia, Rachana Patil, Harinath More, Rutuja Dattatray Chougale

The Thai Journal of Pharmaceutical Sciences

Background: The present study aimed to systematically develop and validate a robust, rapid, and stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of metformin and glimepiride in fixeddose combination tablets. Method development was guided by a design of experiments (DoE) approach using the Box-Behnken design (BBD) to ensure optimal analytical performance.
Materials and Methods: Chromatographic separation was achieved on a Cosmosil C18 column using an optimized mobile phase of acetonitrile and water (80:20, v/v) adjusted to pH 3.5. The flow rate was 1 mL/min, and detection was performed at 221 nm. The BBD approach systematically evaluated the …