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Exploring Primary Care Providers’ Compassionate Care And Their Evidence-Based Practice With Death, Grief, And Loss: Patient Experience And Perspective, Kathryn Krzykala

Dissertations

Research on primary care providers’ (PCPs) education regarding Death, Grief, and Loss (DGL) remains limited. Specifically, data is lacking regarding patients' perceptions and opinions on what they need and expect from their PCPs regarding grief and loss. This exploratory mixed-method study comprised 146 participants who had experienced death and non-death loss. It examined participants' perceptions of 1) PCP compassion, 2) PCP utilization of evidence-based grief and loss practices, 3) their own level of comfort discussing DGL with their PCPs during medical visits, and 4) their personal grief and loss experiences. The findings revealed that PCPs' grief-informed evidence-based treatment, as reflected …

Vegf-A Mediates Red Light-Induced Enos Expression In Human Microvascular Endothelial Cells, Iman Zuberi, Helen Brown, Nicole Lohr

Expo Student Presentations

2026 Summer Expo Poster Presentation

• Biological & Life Sciences

Evaluating Variety- And Market-Class-Specific Effects Of Dietary Pulses On Human Health, Jiayu Tang

Department of Food Science and Technology: Dissertations, Theses, and Student Research

While pulses are globally recognized for their high levels of dietary fibers, protein, and polyphenols, research often focuses on characterizing the physiological effects of a single variety. This approach overlooks the substantial genetic and compositional diversity that exists across pulse varieties and individual market classes, which can differ extensively in nutrient content and structure. These compositional differences have the potential to produce distinct physiological and microbial responses in humans, yet variety- and market-class-specific effects remain poorly characterized.

This thesis uses two complementary research methodologies to investigate the health-relevant effects of different pulse varieties and market classes, providing foundational knowledge to …

Proteogenomics Of Hypertrophic Cardiomyopathy Reveals Subtype-Specific Therapy, Ke Ma, Jie Yang, Hongchang Guo, Ping Li, Xiaowei Li, Zhujun Dong, Jing Zhang, Congcong Zhang, Pengli Yang, Chongpei Hua, Shuolin Zhu, Guoqing Li, Jianchao Zhang, Ningyu Ding, Jizheng Wang, Xin-Liang Ma, Zhuofeng Lin, Jianzeng Dong, Yang Li, Yulin Li

Department of Emergency Medicine Faculty Papers

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease with diverse prognosis. The underlying mechanisms remain unknown, resulting in limited risk stratification and therapeutic strategies. This study aimed to elucidate molecular subtypes of HCM through integrated proteogenomic analysis and explore subtype-specific therapeutic strategies.

METHODS: We conducted an integrated proteogenomic analysis of 132 patients with HCM using myocardial samples, incorporating whole-exome sequencing, RNA sequencing, and proteomics. Unsupervised clustering was used to identify HCM subtypes, which were validated in heart tissues and human induced pluripotent stem cell-derived cardiomyocytes from 2 independent HCM subsets. Subtype-specific signatures and pathways were explored, and their causal link …

A Comparative Study Of Aging And Cortical Folding In Chimpanzees And Olive Baboons, William D. Hopkins, Angela M. Achorn, Michele M. Mulholland, Elizabeth R. Magden, Steven J. Schapiro, Courtney L, Fults, Jean‐Francois Mangin, Adrien Meguerditchian

Anthropology Faculty Publications

In light of the evidence that nonhuman primates naturally develop Alzheimer's disease neuropathologies, there is a renewed interest in research on the comparative biology of aging, including neurological changes across the age groups in species with diverse lifespans. In this paper, we examined age‐related differences in two measures of cortical folding, mean depth and fold opening, in a sample of chimpanzees (Pan troglodytes) and olive baboons (Papio anubis). We found significant species differences in the slope and pattern of age‐related changes in cortical folding. As predicted, chimpanzees showed negative linear associations between age and mean depth and …

Multi-Ancestry Polygenic Risk Scores For The Prediction Of Type 2 Diabetes And Complications In Diverse Ancestries, Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E. Petty, Hong Kiat Ng, Jaewon Choi, Simon Lee, John Blangero

Human Genetics Publications

Background: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global clinical utility. We aimed to deliver comprehensive and rigorously tested multi-ancestry PRSs for prediction in type 2 diabetes.

Methods: We conducted meta-analyses using data from type 2 diabetes genome-wide association studies (GWAS) across cohorts from five major global ancestries: European, African or African American, Admixed American, South Asian, and East Asian. We used summary statistics from the GWAS to construct single-ancestry PRSs (using the continuous-shrinkage PRS-CS …

Valorisation Potential Of Microalgae As A Sustainable Source Of Lipids And Health Promoting Compounds, Bozena Mccarthy

Theses

The transition toward a circular bioeconomy requires sustainable strategies for managing and valorising food industry effluents while reducing reliance on environmentally damaging raw materials such as palm oil, which is associated with deforestation, biodiversity loss and greenhouse gas (GHGs) emissions. Microalgae represent a promising platform for converting nutrient rich industrial by-products into biomass and high-value compounds for food, nutraceutical and bio-based applications. Dairy processing generates large quantities of whey, creating environmental challenges due to its high organic load. Improved whey treatment and valorisation strategies are therefore essential for enhancing sustainability in food production systems. In this study, the biomass productivity …

How Do Different Food Influents Affect Biogas Production, Process And Operational Stability, And System Performance In The Armfield W8, A Bench-Scale Anaerobic Digester, Jarko Rumbaoa, Anahita Adhikari

Rose-Hulman Undergraduate Research Publications

No abstract provided.

Center Of Mass (Com) Shift In Electric Vertical Takeoff And Landing (Evtol) Aircraft, Irene Lema Madueno

Rose-Hulman Undergraduate Research Publications

No abstract provided.

Sustainable Extraction Of A New Diketopiperazine, Anthony Chapman

Rose-Hulman Undergraduate Research Publications

No abstract provided.

Native Plants For Green Roofs In Indiana, Alasdair Curts

Rose-Hulman Undergraduate Research Publications

No abstract provided.

Loss Of Palmitoylation Impacts The Interaction Between The Organic Anion Transporting Polypeptide (Oatp) 1b1 And Oatp1b3., Cecilia E. Villanueva, Whitney M. Nolte, Priscilla Flores-Ascencio, Bruno Hagenbuch

Manuscripts, Articles, Book Chapters and Other Papers

The organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 are hepatic transporters that mediate the uptake of numerous therapeutics like antibiotics and statins. Various post-translational modifications, eg, phosphorylation and glycosylation, have been shown to impact OATP1B1 and OATP1B3 function and localization. S-palmitoylation (also known as S-acylation or palmitoylation) is a reversible post-translational modification that adds palmitic acid (C16:0) to cysteine residues and can influence a protein's function, localization, and protein-protein interactions. In this study, we investigated and characterized palmitoylation in OATP1B1 and OATP1B3. Using site-directed mutagenesis and acyl-resin-assisted capture assays, residue Cys24 was identified as the palmitoylation site for both …

Guide To The Erath Winery Collection, Linfield College Archives

Linfield Archives Finding Aids

The collection was donated by Richard (Dick) Erath, the founder of the Erath Winery in Dundee, Oregon. The collection contains financial information about the Winery, publicity found in newspapers and magazines, personal plans, details of the wine-making process, multiple drafts of the biographical book The Boys Up North; among much other information, and a bottle of the first commercial wine produced by the Erath Winery in 1972.

The Unexpected Role Of Conditionality In Shaping Relational Values: Insights From An Incentive-Based Conservation Program In Bolivia, Brooke Mcwherter, Will Munger, Zhao Ma, Claudia Radel, Laura Zanotti, Jonathan Bauchet, Ricardo Godoy

Department of Agricultural Economics Faculty Publications

As global change accelerates, Payments for Ecosystem Services (PES) programs have become increasingly important tools for addressing the interconnected challenges of land degradation, biodiversity loss, water scarcity, and climate change. PES programs provide incentives to individuals or communities, conditional on people adopting sustainable natural resource management practices to support or increase ecosystem service provisioning. Although conditionality is considered a “PES-defining feature,” little is known about how conditionality is perceived by community members and how such perceptions influence their participation in and experience with PES programs. To address this gap, we conducted an extensive qualitative study of Watershared, an incentive-based conservation …

Mechanistic And Spatio-Temporal Modelling Of Cassava Whitefly (Bemisia Tabaci) Risk Under Climate Change: Projections For Africa With Case Evidence From Malawi, Lumbani Benedicto Banda, Frank Thomas Ndjomatchoua, Ritter A. Guimapi, Komi Mensah Agboka, Abdelmutalab G.A. Azrag, Wezi G. Mhango, Trust Kasambala Donga, Chikondi Makwiza, Karl H. Thunes, Elfatih M. Abdel-Rahman

All Peer-Reviewed Publications

The cassava whitefly (Bemisia tabaci) greatly constrains cassava production across Africa due to its role as a vector of viral diseases that cause substantial yield losses. Effective management of this insect pest requires detailed knowledge of its spatio-temporal distribution, however long-term datasets are scarce. Mechanistic models circumvent these long-term data needs by modelling temperature-dependent processes that govern population dynamics. Nevertheless, their application to B. tabaci remains poorly explored. Here, we developed a mechanistic model to derive a risk index (RI) for B. tabaci across Africa, focusing on Malawi. The model integrates the effects of temperature on the life stages of …

Deconstructing Systemic Sclerosis Heterogeneity: From Patient Subtypes To Pathogenic Fibroblasts, Rezvan Parvizi

Dartmouth College Ph.D Dissertations

This thesis advances heterogeneity as the central barrier both to interpreting therapeutic response and to identifying the molecular regulators that drive fibrosis in systemic sclerosis (SSc). In SSc, heterogeneity is manifest at every level at which the disease can be measured: clinically, in the variable extent of skin and organ involvement; molecularly, in the distinct gene-expression programs that distinguish otherwise comparable patients; and cellularly, in the diverse fibroblast populations from which the fibrotic signal ultimately arises.

Leveraging longitudinal skin transcriptomics from a large cohort treated with mycophenolate mofetil (MMF), the first study demonstrates that intrinsic molecular subtypes are dynamic rather …

Evaluating The Impact Of Region, Vintage, And Carbon Dioxide-Based Winemaking Techniques On Wine Quality Of Mediterranean Varietals, Coleman R. Imrisek

Master's Theses

Changing Vitis vinifera ripening patterns as a result of increasing climate variability has provided challenges against the production of wines with a balanced sensory profile, with adequate acidity, color, aroma, and texture. This thesis aimed to evaluate the ripening patterns and wine profiles of potentially climate-adaptive Mediterranean varietals in two different California Central Coast climates. Additionally, different carbon-dioxide based winemaking techniques were also assessed. Viognier and Grenache Noir grapes were sourced from the warmer, diurnal Paso Robles AVA and the cooler, marine Santa Maria AVA during the 2024 and 2025 growing seasons, with Syrah and Grenache Blanc grapes being only …

Farm Workers And The Structural Basis Of Climate Change Perceptions, Cody Mortell, Anna Erwin, Zhao Ma, Dongkyu Kim, Elizabeth Rodriquez, Marla Perez-Lugo

School of Earth, Environmental, & Marine Sciences Faculty Publications

Farm workers are particularly vulnerable to climate change, especially from extreme heat; however, little is known about how they perceive this risk. This study examines climate change perceptions (CCP) among 404 farm workers surveyed in person in the Lower Rio Grande Valley, Texas from April to May 2024. Guided by Pierre Bourdieu’s theory of practice, we conducted a latent class analysis of economic, cultural, social, and symbolic capital indicators to identify distinct class profiles. We then assessed CCP by latent profile, using two primary outcome variables: (1) perceived temperature trends in the region (assessed alongside NOAA data) and (2) perceived …

An Emergent Seafood Nationalism Takes Hold In The United States, Owen Temby

School of Earth, Environmental, & Marine Sciences Faculty Publications

This paper introduces the concept of ‘seafood nationalism’ to describe how, since 2024–2025, the United States increasingly uses tariffs, trade remedies, food safety enforcement and origin-based rules to favour American seafood over foreign products. Federal actions include Executive Order 14276, Restoring American Seafood Competitiveness, which directs agencies to address unfair trade practices, unsafe imports and to develop a coordinated seafood trade strategy. Additional measures include a tariff package imposing a 10% duty on nearly all seafood imports and 30% on seafood from China, as well as new anti-dumping and countervailing duty orders on warm-water shrimp. This paper presents Gulf …

Alternative Methods To Improve Livestock Performance While Grazing Low-Quality Forages., Ivan Raynard Thomas Jr

Graduate Theses and Dissertations

Stocker cattle producers in the southeastern part of the U.S. heavily depend on traditional forages such as bermudagrass [Cynodon dactylon] pastures during the warm season for grazing. Summer annual forages offer stocker cattle operations a valuable alternative source of forage. These forages have high yield potential and can help extend the grazing season. This is particularly beneficial during the summer months when traditional forage sources may be limited. Warm-season annual grasses may experience a decrease in crude protein concentrations during late summer and early fall. As a result, it may be necessary to find alternative sources of crude protein or …

Effects Of Soil Contamination On The Efficacy Of Antimicrobial Washes For Contaminated In-Shell Pecans, Erin Ramsay

Graduate Theses and Dissertations

A study was done to evaluate the survival of Shiga toxin-producing Escherichia coli (STEC) on directly and soil-inoculated in-shell pecans over a 28-day period, determine STEC reductions after treatment with individual and sequential antimicrobial washes on direct and soil-inoculated in-shell pecans, and determine the cross-contamination potential of the spent pecan washes after a treatment. Pecans were directly and soil-inoculated with an STEC cocktail (O157:H7, O157:NM, O121, and O26). Direct inoculation was achieved by spraying the STEC cocktail on the pecans and homogenizing by hand for 2 min. For the soil-inoculation method, autoclaved pecan tree orchard soil was sprayed with the …

Recent Advances In Phosphatidylinositol Phosphate Kinases (Pipks) And Their Inhibitors, Mengxia Sun, Jian Hu, Xuefei Huang

BAU Journal - Science and Technology

Phosphatidylinositol phosphate kinases (PIPKs) are an important class of enzymes in humans, which produce lipid signaling molecules playing central roles in pathogenesis of diseases such as cancer, neurodegenerative diseases, and viral infection. Consequently, they are attracting increasing attention as drug targets for disease treatment. This review summarizes the functions of the PIPK family enzymes and highlights recent efforts on designing novel inhibitors against PIPKs. These advances are extensively discussed to stimulate interest in this field and promote further development of highly potent and selective inhibitors for innovative therapeutic applications.

Antioxidant And Anti-Hemolytic Capacities Of Eucalyptus Camaldulensis Leaves, Achwaa Chbib, Malak Mezher, Mohamad Nasser, Akram Hijazi, Mahmoud I. Khalil

BAU Journal - Science and Technology

The effects of medicinal plants on the prevention of many diseases are due to their chemical composition. Eucalyptus camaldulensis (E. camaldulensis) is a native tree in Australia. Its extracts and essential oils (EOs) are applicable in the domains of pharmaceuticals and medicine. This work determined the anti-hemolytic and antioxidant capacities of the ethanolic (EE), methanolic (ME), and aqueous (AE) extracts from the leaves of Lebanese E. camaldulensis.  The leaves of E. camaldulensis were extracted with ethanol, methanol, and water solvent. Qualitative phytochemical analyses were applied to reveal the compounds of these extracts. The Folin-Ciocalteau and Aluminum chloride …

Afforestation Strategies In Semi-Arid Mediterranean Ecosystems: Experimental Evidence From Chmistar, Lebanon, Ahmad Saker, Mohammad Saleh, Wael Mostafa, Safaa Baydoun, Jamilah Borjac, Dalia El-Badan

BAU Journal - Science and Technology

The success rate of broadleaf tree growth in semi-arid Mediterranean environments is reduced in afforestation operations constrained by water scarcity, shallow soil depth, and intense competition from herbaceous vegetation. This study, conducted between 2022 and 2024 in Chmistar, East Lebanon, using a completely randomized block design, aimed to evaluate the impact of three planting broadleaf trees techniques (traditional digging pits , hoedad tools, and auger digging) and four effective vegetation control (herbicide application, mowing,  mulching, and no control) on the early growth of three native broadleaf tree species (Pistacia palaestina, Quercus calliprinos, and Quercus infectoria ).

The …

Lesson-1 On Mni Wiconi (Water Is Life): Understanding The Problem Of Water Contamination, Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students investigate a scenario of water contamination in a fictional community. They define the engineering problem of dirty water and explore the cultural and ecological significance of water through the lens of indigenous principles. This lesson introduces students to the concept of water contamination and the need for purification, grounding the learning in a real-world problem and connecting to Indigenous knowledge about the land and water.

Problem-Based Learning (PBL) Scenario: Students receive a letter from a fictional community whose water source has become cloudy and is making people sick. They are tasked with becoming “Water Engineers” to investigate the …

Lesson-2 On Mni Wiconi (Water Is Life): Designing And Testing Solutions (Water Filtration), Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students apply the engineering design process to build, test, and refine a simple water filter prototype. This hands-on experiential learning activity focuses on the properties of filtering materials and iterative problem-solving.  In this lesson, students will apply the engineering design process to build and test their own simple water filters. They will use their newfound knowledge to begin developing a practical solution to the problem presented in Lesson 1 - Mni Wiconi: A Water Engineering Challenge for 4th Graders.

Problem-Based Learning (PBL) Scenario: Having identified the problem, students are now tasked with designing and building a prototype water filter …

Developing Biodegradable Packaging Films And Beads From Agricultural Residues, Sandeep Paudel, Santosh Rijal, Srinivas Janaswamy, Madhav P. Nepal

iLEARN Teaching Resources

Agricultural waste is produced in large amounts worldwide. These are often discarded despite being valuable sources of cellulose and renewable, biodegradable products. At the same time, rising environmental concerns about petroleum-based plastic packaging have created demand for sustainable alternatives. Introducing K-12 students to biodegradable packaging materials developed from agricultural waste can enhance understanding of sustainability, basic materials science, and circular bioeconomy concepts while encouraging interest in STEM fields. Another concern is the presence of microplastics and nanoplastics in drinking water, which can pose serious risks to human health. Traditional coagulation agents, such as ferric and aluminum salts, are less effective …

Lesson-3 On Mni Wiconi (Water Is Life): Analyzing Evidence And Communicating Solutions (Community Stewardship), Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students analyze the data collected from their filter tests, construct an evidence-based argument for their most effective design, and communicate their solution to a “community council” (the class), connecting their technological solution back to community well-being. In the final lesson, students will analyze their data, draw conclusions, and communicate their findings. They will present their improved water filter designs to the class, acting as consultants for the fictional community.

Problem-Based Learning (PBL) Scenario: Students are now ready to present their final water filter prototypes and a summary of their findings to a “community council” (the rest of the class). They …

The Deep Darkness Microbiome: Functional And Taxonomic Diversity In An Oligotrophic Temperate Cave, Philips O. Akinwole, Nina G. Shaffer '25, Emma E.C. Jacobs '25, Zoe Green '27, Thi Doan '27, Crimson Hickman '28, Kaija M. Carr '25, Kenneth L. Brown

Biology Faculty publications

Many subterranean ecosystems are chronically energy limited, yet the mechanisms governing microbial community assembly and metabolic function under extreme carbon scarcity remain poorly resolved. We combined 16S rRNA gene sequencing with community-level physiological profiling (CLPP) to examine how physicochemical gradients regulate microbial diversity and carbon-use strategies across a surface-subsurface transition into the Deep Darkness zone of Indiana Caverns. Progressive isolation from surface inputs resulted in sharp declines in microbial biomass, total organic carbon, and nitrogen, accompanied by increased water content and C:N ratios, indicating strong attenuation of allochthonous organic matter and intensified resource filtering. Microbial communities spanned 42 bacterial phyla, …

Protective Effects Of Yogurt Against Sodium Fluoride-Induced Liver Dysfunction In Rabbits, Rasool Bux, Rehana Buriro, Shamsuddin Bughio, Kashif Ali Malak, Muhammad Aqeel, Fayaz Ali, Ali Raza, Abdul Sallam

Journal of Bioresource Management

Fluoride (F-) is among the most important compounds that can damage hepatic tissue and increase level of ALT, ALP, Bilirubin, GGT, and decreases the albumin. Present study was conducted to explore protective role of yogurt on hepatic dysfunction induced by sodium F- at different doses. Animal were divided into seven experimental groups (6 rabbits/group). Group A (Control), Group B (F- 50 mg/kg), Group C (yogurt 15 g/kg), Group D (F- 50 mg + yogurt 15 g/kg), Group E (F- 100 mg/kg), Group F (yogurt 30 g/kg), Group G (F- 100 mg/kg B.W. + yogurt 30 g/kg). In F- treatment groups …