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Articles 1981 - 2010 of 49571
Full-Text Articles in Entire DC Network
Prediction Model Of Storage Quality Change And Shelf Life Of Dried Pork Slice, Chen Xiaohe, Qian Ping, Huang Ning, Yang Ran, Qu Lingbo, Zhao Changcheng, Li Chunxia
Prediction Model Of Storage Quality Change And Shelf Life Of Dried Pork Slice, Chen Xiaohe, Qian Ping, Huang Ning, Yang Ran, Qu Lingbo, Zhao Changcheng, Li Chunxia
Food and Machinery
[Objective] To investigate the quality changes of dried pork slices under different temperature storage conditions and to predict their shelf life. [Methods] Hardness, color parameters (L* value, a* value, b* value ), and sensory quality of dried pork slices were investigated under storage at 25, 35, 45, and 55℃. Pearson correlation analysis was performed for each index, and the key index was fitted using a dynamic model. Combining the Arrhenius equation with the Q10 model, a shelf life prediction model was established. [Results] Under storage at 25, 35, 45, and 55 ℃, the a* value of dried pork slices decreased …
Optimization Of Bioethanol From Plantain Peel Using Saccharomyces Cerevisiae, Akinjide A. Akinola, Olawole O. Olanipekun, Paul A. David
Optimization Of Bioethanol From Plantain Peel Using Saccharomyces Cerevisiae, Akinjide A. Akinola, Olawole O. Olanipekun, Paul A. David
Mansoura Engineering Journal
This research aimed to evaluate the potential of using plantain peels as a raw material for producing bioethanol with the help of Saccharomyces cerevisiae. The study utilized a four-factor Box-Behnken design (BBD) and response surface methodology (RSM) to optimize the fermentation conditions. The factors considered for optimization were substrate concentration (1-4 g), pH (5-7), temperature (30-45°C), and fermentation time (24-96 hours). Through this optimization process, the study found that the optimal conditions for bioethanol production were 4 g substrate concentration, pH 6, 45°C temperature, and 60 hours of fermentation time. Utilizing these optimal conditions resulted in a bioethanol yield of …
Is There An Extension Discount For Agricultural Economics Faculty?, Siun Lee, Jeffrey Hyde, Yangxuan Liu, Rodolfo M. Nayga Jr, Wendong Zhang
Is There An Extension Discount For Agricultural Economics Faculty?, Siun Lee, Jeffrey Hyde, Yangxuan Liu, Rodolfo M. Nayga Jr, Wendong Zhang
Journal of Extension
Salary is an important aspect of one’s decision to pursue a particular career. This work compares the salaries of Agricultural Economics faculty members with and without Extension responsibilities across 19 departments in the US. We find that mean salaries for those with Extension appointments are significantly less than those without Extension appointments, ranging from a difference of $5,065 for assistant professors to $14,532 for full professors. We encourage administrators to acknowledge this “Extension Discount” and, if desired, make intentional decisions to reduce it. Doing so would serve to address recruiting challenges for Agricultural Economics Extension positions.
Allergenai: A Deep Learning Model Predicting Allergenicity Based On Protein Sequence, Catherine H Schein, Werner Braun, Pora Kim
Allergenai: A Deep Learning Model Predicting Allergenicity Based On Protein Sequence, Catherine H Schein, Werner Braun, Pora Kim
Faculty, Staff and Student Publications
BACKGROUND: Innovations in protein engineering offer promising solutions for redesigning allergenic proteins to minimize adverse reactions in sensitive individuals. Earlier models for predicting allergenicity have relied on the knowledge of physicochemical properties and sequence homology to assess the potential risk. However, to better understand the allergenic proteins’ sequence features, we need a novel sequence-based deep learning model for predicting allergenicity.
RESULTS: We present a novel AI-based tool, AllergenAI, to quantify the allergenic potential of a protein’s sequence without using any other known features. Our study utilized allergenic protein sequence data archived in the three well-established databases, SDAP 2.0, COMPARE, and …
The Impact Of Domed Architecture On The Architectural Character Of Western Desert Oases, Nader Mohamed Gharib, Mo’Men Abdelqader, Yousab Magdy Shafik
The Impact Of Domed Architecture On The Architectural Character Of Western Desert Oases, Nader Mohamed Gharib, Mo’Men Abdelqader, Yousab Magdy Shafik
Mansoura Engineering Journal
The visual disharmony arising from the indiscriminate and architecturally unplanned integration of curved roofing elements, notably domes, into the built environment of the Western Desert oases has become a significant issue, particularly in the Siwa Oasis, where the adoption of domed architecture was first introduced in the village of Jafar in 1997. This research delves into a detailed study that focuses on how pivotal historical, cultural, environmental, aesthetic, functional, and technical factors have crucially shaped the widespread integration of these iconic curved roofing superstructures in the oases' architectural heritage over generations, contributing to the uniquely recognizable architectural character and sense …
Prognosis And Treatment Response Stratification According To Loss Of Proofreading (Lop), Giulia Maddalena, Fadl A Zeineddine, Saikat Chowdhury, Mohammad A Zeineddine, Abdelrahman M Yousef, Sara Lonardi, Michael Geoffrey White, Michael J Overman, Scott Kopetz, John Paul Shen
Prognosis And Treatment Response Stratification According To Loss Of Proofreading (Lop), Giulia Maddalena, Fadl A Zeineddine, Saikat Chowdhury, Mohammad A Zeineddine, Abdelrahman M Yousef, Sara Lonardi, Michael Geoffrey White, Michael J Overman, Scott Kopetz, John Paul Shen
Faculty, Staff and Student Publications
Background: Only a subset of polymerase epsilon (POLE) mutations is associated with hypermutant phenotype; we hypothesized that only loss-of-proofreading (LOP) POLE mutations are associated with favorable immunotherapy response.
Methods: This retrospective cohort study included a pan-cancer cohort of 69,223 patients from cBioPortal and a cohort of patients with 41 POLE mutant metastatic colorectal (CRC) treated with immunotherapy at the MD Anderson Cancer Center between January 2017 and May 2023. We evaluated prognosis according to POLE mutation functionality.
Results: In the pan-cancer cBioPortal cohort (n=69,223) POLE was mutated in 2.8% (1,965) of tumors; of these, only 7.5% (n=148) had …
Indigenous And Tribal Nation Scientists And Universities, Elizabeth A. Sumida Huaman, Stephen J. Smith
Indigenous And Tribal Nation Scientists And Universities, Elizabeth A. Sumida Huaman, Stephen J. Smith
Critical Internationalization Studies Review
No abstract provided.
Interview With Orca Award Winner James Van Etten, Unl Plant Pathology; Discoverer Of Giant Viruses, Mark Griep, James Van Etten
Interview With Orca Award Winner James Van Etten, Unl Plant Pathology; Discoverer Of Giant Viruses, Mark Griep, James Van Etten
UNL ORCA Interview Series
Dr. James Van Etten was awarded the UNL Outstanding Research and Creative Activities Award in 1992. He was born in Virginia but grew up Peoria, Illinois. Something in his youth must have sparked an interest in science because he earned his bachelor’s degree in biology from Carleton College in 1960. Carleton is a well-regarded liberal arts institution in Northfield, Minn., about 400 miles from Peoria. Next, Jim earned a master’s and doctorate at the University of Illinois in Champaign-Urbana, both in plant pathology. For his postdoctoral work in 1965 and 1966, he did postdoctoral work in the Department of Genetics …
11.17.2025 Ored Connect, Liz Williamson
11.17.2025 Ored Connect, Liz Williamson
ORED Newsletter
- Qualtrics training sessions
- Alcorn State University, Dr. Edmund Buckner
Advanced Plant Growth Using Halloysite Nanotubes (Hnts) And Waste Extraction For Medical Applications, Zeinab Jabbari Velisdeh
Advanced Plant Growth Using Halloysite Nanotubes (Hnts) And Waste Extraction For Medical Applications, Zeinab Jabbari Velisdeh
Doctoral Dissertations
This dissertation presents an integrated research framework that bridges nanotechnology, green chemistry, and sustainable agriculture, aiming to address two critical global challenges: enhancing plant growth under resource-limited conditions and valorizing agricultural waste for bioactive compound extraction. The study is divided into three major projects that together highlight the innovative application of magnesium oxide-coated halloysite nanotubes (MgO-HNTs) and the development of environmentally conscious extraction methods for high-value phytochemicals. The first component of this work investigates the design, fabrication, and functional evaluation of MgO-HNTs as advanced nanocarriers for promoting seed germination and early root development in tomato plants. MgO-HNTs were synthesized via …
Advances In The Discovery Of Active Natural Products By Large Fragment Cloning, Dandan Zeng, Jiayu Chen, Tianlu Mo
Advances In The Discovery Of Active Natural Products By Large Fragment Cloning, Dandan Zeng, Jiayu Chen, Tianlu Mo
Journal of Food Science and Biotechnology
Active natural products have diverse structures and activities and can be a major source of small molecule drugs.Given the emergence of multi-drug resistant bacteria and superbacteria,there is an urgent need to develop new active natural products.Large fragment cloning has been an important tool for the discovery of active natural products in recent years,and it has demonstrated obvious advantages in obtaining the biosynthetic gene clusters of active natural products.This approach,combined with efficient cluster-targeted screening methods,has significantly accelerated the discovery of active natural products.This review summarizes a wide variety of active natural products.Furthermore,this paper elaborates on the principles and applications of several …
Preparation And Application Of A Polyclonal Antibody To Chlamydomonas Reinhardtii Rsp 10, Chan Lu, Yuanyuan Zhang, Ye Tao, Zhenchuan Fan, Yanxia Liu
Preparation And Application Of A Polyclonal Antibody To Chlamydomonas Reinhardtii Rsp 10, Chan Lu, Yuanyuan Zhang, Ye Tao, Zhenchuan Fan, Yanxia Liu
Journal of Food Science and Biotechnology
[Objective ] This study aims to explore the cilium assembly of the radial spoke protein RSP 10 and develop a highly specific polyclonal antibody to RSP 10.[Method ] Firstly,the prokaryotic expression vector pMal-C 2X-rsp10 was constructed,and the expression of MBP-labeled RSP 10 was induced in Escherichia coli BL21 (DE3).After the fusion protein was purified,and the MBP label was excised.The obtained protein was used to immunize New Zealand male white rabbits,and the antibody titer in the anti-serum was determined by indirect ELISA.[Result ] The rabbit anti- Chlamydomonas reinhardtii RSP 10 antibody with high specificity and high sensitivity was obtained after purification …
Fabrication And Antioxidant Property Characterization Of Caffeic Acid Phenethyl Ester-Loaded Nanoparticles, Yaqiong Chen, Yumeng Li, Hui Wu, Hongdong Song, Xiao Guan
Fabrication And Antioxidant Property Characterization Of Caffeic Acid Phenethyl Ester-Loaded Nanoparticles, Yaqiong Chen, Yumeng Li, Hui Wu, Hongdong Song, Xiao Guan
Journal of Food Science and Biotechnology
[Objective ] This study aims to improve the dispersion and utilization of caffeic acid phenethyl ester (CAPE ) in aqueous solutions.[Method ] CAPE-loaded hordein (CAPE-HD ) nanoparticles were constructed via an anti-solvent precipitation method.The physicochemical properties of the nanoparticles were characterized,and the antioxidant properties of the nanoparticles within Caco- 2 cells were investigated.[Result ] The components within the CAPE-HD nanoparticles interacted through non-covalent bonds,such as hydrogen bonding,resulting in an altered state of CAPE upon nanoparticle formation.The CAPE-HD nanoparticles exhibited near-spherical morphology with an average particle size of 193.93 nm,an average polydispersity index (PDI) of 0.26,and average Zeta potential of 14.50 …
Bacterial Diversity In Milk And Traditionally Fermented Dairy Products In Balin Right Banner, Lijuan Liu, Gaowa Bai, Jinghe Yu, Fang Wang, Youyi Zhang, Li Zhu, Dalai Wuyun
Bacterial Diversity In Milk And Traditionally Fermented Dairy Products In Balin Right Banner, Lijuan Liu, Gaowa Bai, Jinghe Yu, Fang Wang, Youyi Zhang, Li Zhu, Dalai Wuyun
Journal of Food Science and Biotechnology
[Objective ] This study explored the bacterial diversity in milk and traditional fermented dairy products in Balin Right Banner,aiming to lay a foundation for the development and utilization of bacterial resources in the milk and traditional fermented dairy products in this region.[Method ] A total of 32 samples of cow milk,milk tofu,and sour fermentation supernatant of milk tofu were collected from Balin Right Banner,and their bacterial diversity was analyzed by 16S rRNA high-throughput sequencing.[Result ] The diversity and abundance of bacterial communities varied among the milk and traditional fermented dairy products in Balin Right Banner.The dominant bacterial phyla were Firmicutes …
A Zif- 8 Electrode Immobilizing Enzyme For Detection Of Glucose Solution In Food, Tingmei Ma, Shouxin Tang, Wenpan Shi, Yuchen Ma, Haijun Du
A Zif- 8 Electrode Immobilizing Enzyme For Detection Of Glucose Solution In Food, Tingmei Ma, Shouxin Tang, Wenpan Shi, Yuchen Ma, Haijun Du
Journal of Food Science and Biotechnology
[Objective ] The aim was to construct an electrochemical sensor based on a metal-organic framework-modified electrode for the highly sensitive detection of glucose solution in beverages.[Method ] An electrochemical sensor based on ZIF- 8 composite carbon nanotubes and immobilizing glucose oxidase (GOx ) was prepared by in-situ synthesis and immobilized enzyme technology.The microstructure and morphology of the material were characterized by X-ray diffraction (XRD ),scanning electron microscopy (SEM ),UV-Vis spectroscopy,and infrared spectrometry (IR).The electrochemical performance of the electrode immobilizing enzyme was tested by electrochemical workstation.[Result ] The prepared electrode immobilizing enzyme showed excellent detection performance for glucose solution,with a limit …
Establishment Of A Molecularly Imprinted Electrochemical Sensor Nh 2-Mwcnts@ 4-Fpba For The Detection Of Epidermal Growth Factor In Dairy Products, Ruyue Zhang, Yiwei Wang, Hongxiu Zeng, Bini Wang, Fuxin Zhang, Zhenquan Huo, Yufang Liu
Establishment Of A Molecularly Imprinted Electrochemical Sensor Nh 2-Mwcnts@ 4-Fpba For The Detection Of Epidermal Growth Factor In Dairy Products, Ruyue Zhang, Yiwei Wang, Hongxiu Zeng, Bini Wang, Fuxin Zhang, Zhenquan Huo, Yufang Liu
Journal of Food Science and Biotechnology
[Objective ] This study aims to develop a rapid and accurate method for detecting epidermal growth factor (EGF ).[Method ] 4-Formylphenylboronic acid (4-FPBA ) was covalently anchored to the surface of aminocarbon nanotubes (NH 2-MWCNTs ) to synthesize nanocomposites (NH 2-MWCNTs@ 4-FPBA ),and NH 2-MWCNTs@ 4-FPBA was modified on a glassy carbon electrode.When EGF was present,4-FPBA captured the EGF template through benzaldehyde,and then the electrode was immersed in pyrrole solution to electropolymerize to form a pyrrole molecularly imprinted layer.Finally,after dissociation and removal of the EGF template in an acidic solution,a three-dimensional cavity complementary to the EGF template was formed.[Result ] …
Comparison Of The Bioactivities Of Ziziphus Jujuba Polysaccharide And Its Degradation Products, Chunling Zhou, Xiaoyan Huang, Xuan Zheng, Ju Zhang
Comparison Of The Bioactivities Of Ziziphus Jujuba Polysaccharide And Its Degradation Products, Chunling Zhou, Xiaoyan Huang, Xuan Zheng, Ju Zhang
Journal of Food Science and Biotechnology
[Objective ] This study aims to compare Ziziphus jujuba polysaccharide (ZJP) and its degradation products in terms of their chemical composition and bioactivities.[Method ] ZJP was degraded by α-L-rhamnosidase,cellulase,snail enzyme,and trifluoroacetic acid to prepare different degradation products (ZJP-R,ZJP-C,ZJP-S,and ZJP-T ),and the chemical composition and degradation effects were compared.On the basis of in vitro antioxidant and probiotic activities,the in vivo antioxidant,anti-aging,anti-stress,and neuroprotective activities of ZJP and its degradation products were compared with Caenorhabditis elegans as a model system.[Result ] The mass fraction of reducing sugar and average degree of polymerization of ZJP showed significant variations among different degradation treatments.In addition,Sephadex G- …
Effects Of Α-Amylase Addition On The Characteristics Of Infant Rice Flour, Huihui Liu, Zhiyong Dai, Mengyi Li, Jiao Peng, Xing Meng, Luyan Liao, Rongbin Zhang
Effects Of Α-Amylase Addition On The Characteristics Of Infant Rice Flour, Huihui Liu, Zhiyong Dai, Mengyi Li, Jiao Peng, Xing Meng, Luyan Liao, Rongbin Zhang
Journal of Food Science and Biotechnology
[Objective ] This study aims to investigate the effects of α-amylase addition on the characteristics of infant rice flour.[Method ] Infant rice flour samples with different α-amylase addition were prepared.The basic composition,relative molecular mass of starch,gelatinization properties,hydration properties,texture properties,in vitro digestion characteristics,and microstructure of infant rice flour were determined.Furthermore,the correlations between the physicochemical characteristics and quality characteristics of infant rice flour were analyzed.[Result ] The weight-averaged molecular weight and the number-averaged molecular weight of starch in infant rice flour decreased with the increase in α-amylase addition.The gelatinization curve of infant rice flour with α-amylase addition was relatively gentle,and the gelatinization …
Effects Of Spices On Microbial Community Structure And Volatile Flavor Components Of Fuling Pickled Mustard Tuber, Ting Ren, Yuling Liu, Zhiping Zhao, Xiaoyong Chen, Yumei Peng, Hong Tao, Yuanli Luo
Effects Of Spices On Microbial Community Structure And Volatile Flavor Components Of Fuling Pickled Mustard Tuber, Ting Ren, Yuling Liu, Zhiping Zhao, Xiaoyong Chen, Yumei Peng, Hong Tao, Yuanli Luo
Journal of Food Science and Biotechnology
[Objective ] This study aims to investigate the effects of spices on the microbial community structure and volatile flavor compounds of Fuling pickled mustard tuber and explore the correlations between dominant microbial genera and volatile components.[Method ] The effects of spices on microbial community structure and volatile flavor components of Fuling pickled mustard tuber were investigated by high-throughput sequencing and headspace solid-phase microextraction (HS-SPME ) coupled with gas chromatography-mass spectrometry (GC-MS ).Pearson correlation coefficients were calculated to reveal the correlations between dominant microbial genera and volatile components.The mass fractions of total acids,nitrite,and reducing sugar were determined.[Result ] The dominant microbial …
Effects And Mechanisms Of Phytosterol-Oil Bodies Emulsion On Lipid Metabolism Of Caenorhabditis Elegans, Jie Sun, Mengyuan Yuan, Yifei Liu, Fuyao Zhang, Zhuofan Yang, Guoyou Yin
Effects And Mechanisms Of Phytosterol-Oil Bodies Emulsion On Lipid Metabolism Of Caenorhabditis Elegans, Jie Sun, Mengyuan Yuan, Yifei Liu, Fuyao Zhang, Zhuofan Yang, Guoyou Yin
Journal of Food Science and Biotechnology
[Objective ] This study aims to explore the lipid-lowering effects of the phytosterol-oil bodies emulsion (POE ).[Method ] Caenorhabditis elegans was taken as a model to evaluate the effects of POE on lipid metabolism,physiological indexes,and expression of genes associated with oxidative stress and fat metabolism.[Result ] Compared with the control group,different mass concentrations of POE reduced the mass fraction of fat (P<0.01) and the relative content of triglycerides (P<0.05),without toxicity to the growth and development of C.elegans (P<0.01).At the same time,it significantly reduced the level of reactive oxygen species and increased the levels of antioxidant enzymes.In addition,POE affected the expression levels of genes related to fat metabolism.qPCR results showed that POE up-regulated the mRNA level of sbp-1,while down-regulating the mRNA levels of fat-2,nhr-80,and fat-5 (P<0.05).[Conclusion ] POE may improve lipid metabolism by slowing fat deposition,regulating the fat peroxidation pathway,and alleviating oxidative stress in C.elegans.
Optimization Of The Fermentation Medium Of Aneurinibacillus Jxn- 1 For Caproic Acid Production, Guangdong Gan, Chunlin Zhang, Ting Huang, Junjun He, Chun Pu, Wei Shi, Mingye Peng, Tengfei Zhao
Optimization Of The Fermentation Medium Of Aneurinibacillus Jxn- 1 For Caproic Acid Production, Guangdong Gan, Chunlin Zhang, Ting Huang, Junjun He, Chun Pu, Wei Shi, Mingye Peng, Tengfei Zhao
Journal of Food Science and Biotechnology
[Objective ] This study aims to increase the caproic acid yield of Aneurinibacillus JXN- 1.[Method ] First,a Plackett-Burman design was employed to screen the significant factors affecting caproic acid yield from eight medium components.Subsequently,the path of steepest ascent method was used to determine the optimal concentration ranges of these significant factors.Finally,a Box-Behnken design was utilized to establish a quadratic polynomial regression model,and the interactions among the significant factors were analyzed to predict the optimal medium composition.[Result ] The Plackett-Burman design identified the mass concentration s of sodium acetate and calcium folinate and the volume fraction of ethanol as significant influencing …
Applied Research In Field Crop Pathology For Indiana, 2024, Darcy E. P. Telenko, Sujoung Shim
Applied Research In Field Crop Pathology For Indiana, 2024, Darcy E. P. Telenko, Sujoung Shim
Purdue University Press Books
Applied Research in Field Crop Pathology for Indiana, 2024 serves as a summary of the applied field crop pathology research trials conducted in 2024 under the direction of the Purdue Field Crop Pathology program in the Department of Botany and Plant Pathology at Purdue University. In Indiana, there are more than 57,600 farms, 16,000 crop producers, and 900 certified crop advisers, Extension educators, and crop-protection industry representatives who manage more than 11.4 million crop-production acres with a total value of $6.3 billion annually. There are more than twenty diseases affecting corn, soybeans, and wheat that may decrease crop production and …
Seismic Responsive Buildings: Comparison Between Egyptian Code 2012 With Different International Codes For Seismic Structural Irregularities At Architectural Design, Aya Abd El Ghaffar Mohamed, Mohamed Anwar Mohamed Fikry, Mai Mohamed Abdo
Seismic Responsive Buildings: Comparison Between Egyptian Code 2012 With Different International Codes For Seismic Structural Irregularities At Architectural Design, Aya Abd El Ghaffar Mohamed, Mohamed Anwar Mohamed Fikry, Mai Mohamed Abdo
Mansoura Engineering Journal
Seismic codes are laws and regulations that establish the basic requirements for building structures that can withstand seismic activity. Each country has different restrictions under different subheadings, depending on the seismic history of the region and the economic situation of the country. "Structural irregularity" is the most significant aspect of earthquake codes contributing to architectural design. A regular design of a structure leads to more rational behavior during earthquakes, enhancing resistance to dynamic loads and economic performance in comparison to irregular buildings. Architects must understand how earthquakes impact structures, as the structural system shapes the building's form and aesthetics, and …
How Can Smart Resilience Cities Provide Sdgs? An Integrative Framework Regarding Climate Change Mitigation, Asmaa M. Hassan, Manar A. Kotb
How Can Smart Resilience Cities Provide Sdgs? An Integrative Framework Regarding Climate Change Mitigation, Asmaa M. Hassan, Manar A. Kotb
Mansoura Engineering Journal
Urbanization and climate change influence public health and wellbeing, which presents challenges facing architects and urban planners towards providing sustainable and resilient cities. In this context, smart city concept has been adopted to contribute to mitigating such influence. This study aims to conduct a bibliometric analysis within the previous scope. Then an integrative framework for climate change mitigation towards resilient smart cities based on SDGs is accomplished. The results indicate that further efforts are needed to develop “smart tools”, “urban economy”, and “carbon footprint. In addition, the proposed framework provides a significant paradigm shift towards mitigation of climate change impacts, …
Population Structure Analysis Of Four Basal Higher-Attines Using Bioinformatic Approaches, Gabriel Mcdanield
Population Structure Analysis Of Four Basal Higher-Attines Using Bioinformatic Approaches, Gabriel Mcdanield
Biology Theses
Metapopulations within the family Formicidae are unique among other animals due to the large colonies they build, and the mating strategies required to fertilize a specialized reproductive caste that will often produce young for the life of the colony. One group of ants, the fungus-gardeners (tribe Attini). The population structure of North American non-leafcutting, fungus-gardening ants has been understudied, especially in the southwest of the United States. Additionally, not much is known about their dispersal biology, so the dynamics of dispersal of these species and how they affect population structure is likewise not well known. To shed light on the …
Chronosort: Revealing Hidden Dynamics In Alphafold3 Structure Predictions, Matthew J. Argyle, William P. Heaps, Corbyn Kubalek, Spencer Gardiner, Bradley C. Bundy, Dennis Della Corte
Chronosort: Revealing Hidden Dynamics In Alphafold3 Structure Predictions, Matthew J. Argyle, William P. Heaps, Corbyn Kubalek, Spencer Gardiner, Bradley C. Bundy, Dennis Della Corte
Faculty Publications
Protein function emerges from dynamic conformational changes, yet structure prediction methods provide only static snapshots. While AlphaFold3 (AF3) predicts protein structures, the potential for extracting dynamic information from its ensemble predictions has remained underexplored. Here, we demonstrate that AF3 structural ensembles contain substantial dynamic information that correlates remarkably well with molecular dynamics simulations (MD). We developed ChronoSort, a novel algorithm that organizes static structure predictions into temporally coherent trajectories by minimizing structural differences between neighboring frames. Through systematic analysis of four diverse protein targets, we show that root-mean-square fluctuations derived from AF3 ensembles can correlate strongly with those from MD …
Rabies Virus-Vectored Lyme Disease Vaccine Provides Long-Term Protection Against Tick-Transmitted Borrelia Burgdorferi, Shantel Rios, Bibek Bhattachan, Christoph Wirblich, Anisha Chandwani, Kruthi Vavilikolanu, Jacob F. Myers, Chrysoula Kitsou, Utpal Pal, Matthias J. Schnell
Rabies Virus-Vectored Lyme Disease Vaccine Provides Long-Term Protection Against Tick-Transmitted Borrelia Burgdorferi, Shantel Rios, Bibek Bhattachan, Christoph Wirblich, Anisha Chandwani, Kruthi Vavilikolanu, Jacob F. Myers, Chrysoula Kitsou, Utpal Pal, Matthias J. Schnell
Department of Microbiology and Immunology Faculty Papers
Lyme disease (LD) cases have doubled globally. LD is a tick-borne illness caused by the Borrelia burgdorferi sensu lato (Bb). If untreated, Bb can disseminate to distal organs, causing carditis, arthritis, and meningitis. Currently, no FDA-approved human LD vaccine exists on the market. This study used two approaches to incorporate OspA into the rabies virus (RABV) vaccine vector. We used the RABV-glycoprotein tail (RVG tail) and the Hendra virus (HeV) glycoprotein tail (HVG tail) to incorporate OspA, creating BNSP333-OspA-RVG and BNSP333-OspA-HVG, respectively. Both vaccines produced type-1 biased anti-OspA antibodies, but only BNSP333-OspA-HVG induced neutralizing antibodies and protected against Bb infection. …
The Effects Of Visual And Audio Secondary Cognitive Tasks During Landing: A Statistical Parametric Mapping Analysis Of Hip And Knee Biomechanics, Hillary Nguyen, Amber Lyle, Kevin Tran, Dominic Espinoza, Gerwyn Hughes
The Effects Of Visual And Audio Secondary Cognitive Tasks During Landing: A Statistical Parametric Mapping Analysis Of Hip And Knee Biomechanics, Hillary Nguyen, Amber Lyle, Kevin Tran, Dominic Espinoza, Gerwyn Hughes
International Journal of Exercise Science
International Journal of Exercise Science 18(7): 1367-1380, 2025. https://doi.org/10.70252/KGHI3479 ACL injuries often occur when athletes perform cognitive tasks while performing a landing/cutting movement. This study investigated the effects of secondary cognitive tasks on hip and knee biomechanics during single limb landing. Sixteen recreational athletes (10 females and 6 males, age: 21.6 ± 2.5 years, mass: 65.2 ± 8.9 kg, height 1.66 ± 0.07 m) performed landings on their dominant limb as a single task and while simultaneously performing secondary cognitive tasks (mental arithmetic) provided through audio and visual means. Hip and knee joint angles and moments were calculated in all …
Data Cleaning With Excel, Rubab Shahzad
Data Cleaning With Excel, Rubab Shahzad
Day Family Research Lab Workshop Series
This workshop will delve into the importance of cleaning research data and why clean data is an important part of the larger research data lifecycle. This session will also provide an overview of data cleaning and preprocessing using Microsoft Excel including a hands-on demonstration.
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Adsorptive Removal Of Arsenite And Cobalt By Commercial Sorbents, Sevda Joudiazar, Sushma Yadav, Zhiming Zhang, Anshuman Satpathy, Eustace Fernando, Roxana Rahmati, Junchul Kim, Rupali Datta, Dibyendu Sarkar
Adsorptive Removal Of Arsenite And Cobalt By Commercial Sorbents, Sevda Joudiazar, Sushma Yadav, Zhiming Zhang, Anshuman Satpathy, Eustace Fernando, Roxana Rahmati, Junchul Kim, Rupali Datta, Dibyendu Sarkar
Michigan Tech Publications
Despite the prevalence and toxicity of heavy metals in the environment, arsenic and cobalt are of particular concern due to their high mobility and bioaccumulation potential, particularly in contaminated groundwater. Herein, we studied the adsorption behavior of commercially available sorbents, including Fluorosorb-100 (FS-100), Fluorosorb-200 (FS-200), and Filtrasorb-400 (F-400), for the removal of arsenite (As(III)) and cobalt (Co(II)), aiming at the selection of filter media in terms of future groundwater remediation. Kinetic analysis revealed that As(III) adsorption followed a pseudo-second-order model, while Co(II) showed mixed first- and second-order behavior, reflecting sorbent-dependent mechanisms. Equilibrium isotherm modeling revealed strong correlations with both Langmuir …