Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Life Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 1051 - 1080 of 49453

Full-Text Articles in Entire DC Network

Alfred Russel Wallace Notes 39. What About Wallace's 'Agnosticism'...?, Charles H. Smith Mar 2026

Alfred Russel Wallace Notes 39. What About Wallace's 'Agnosticism'...?, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823−1913) seems to have distinguished his earlier years of agnosticism from his later period as a spiritualist, but a closer look at the situation suggests he actually remained an agnostic all the way through to the end of his life. The confusion is occasioned by a lack of terminology that can be applied to his position, which most closely resembles a Spinozian manner of thinking.


Widespread Decline In The Abundance Of Sea Cucumber Assemblages In Atolls Of The Protected Rowley Shoals, Northwestern Australia, Inês Leal, Claire L. Ross, Simone Strydom, Richard D. Evans, Thomas H. Holmes, Graham J. Edgar, John K. Keesing Mar 2026

Widespread Decline In The Abundance Of Sea Cucumber Assemblages In Atolls Of The Protected Rowley Shoals, Northwestern Australia, Inês Leal, Claire L. Ross, Simone Strydom, Richard D. Evans, Thomas H. Holmes, Graham J. Edgar, John K. Keesing

Research outputs 2022 to 2026

The Rowley Shoals, off northwestern Australia, are renowned as a biodiversity hotspot. This remote system comprises three atolls, Clerke, Imperieuse and Mermaid, which in recent years have been increasingly targeted by illegal fishing, a pressure rising across the Indo-Pacific. The objective of this study was to quantify recent changes in sea cucumber assemblages across the Rowley Shoals. We surveyed nine sea cucumber species at monitoring sites in 2018 and 2023 to assess changes in their abundance. Total assemblage densities declined significantly across all atolls and habitats. Documented seizures of illegally harvested holothurians by the Australian Fisheries Management Authority over this …


Utah Farmers Markets Impact Report: Strengthening Local Food Systems, Economic Resilience, And Community Well-Being, Jaclyn Pace, Steven Price, Roslynn Brain-Mccann, Joshua Cafferty, Blue Cook Mar 2026

Utah Farmers Markets Impact Report: Strengthening Local Food Systems, Economic Resilience, And Community Well-Being, Jaclyn Pace, Steven Price, Roslynn Brain-Mccann, Joshua Cafferty, Blue Cook

All Current Publications

Utah's farmers markets are more than places to shop — they are essential community infrastructure. With more than 60 markets in operation across the state, people rely on their local market for food, leisure, and community connection. From 2023–2025, the Utah Farmers Market Network (UFMN) and Utah State University (USU) Extension led a three-year, mixed-methods evaluation to document the economic and social contributions of farmers markets across the state. Over three market seasons, more than 230,000 customer responses were collected at markets in St. George, Cedar City, Hurricane, Ogden, Murray, Wheeler Farm, Millcreek, Downtown Salt Lake City, and Price — …


Pre- And Postnatal Exposure To Pm2.5 And No2 And Blood Pressure In Children: Results From The Echo Cohort, Yu Ni, Andrew Law, Xingyu Gao, Adam A Szpiro, Christine T Loftus, Miranda Jones, Logan C Dearborn, Marnie F Hazlehurst, Allison R Sherris, Sindana Ilango, Kaja Z Lewinn, Nicole R Bush, Qi Zhao, Leonardo Trasande, Joseph T Flynn, Daniel A Enquobahrie, Ruby H N Nguyen, Tom O'Connor, Arpita K Vyas, Mingyu Zhang, Hooman Mirzakhani, Alison Hipwell, Anne Starling, Alicia K Peterson, Akhgar Ghassabian, Assiamira Ferrara, Judy Aschner, Scott Collingwood, Margaret R Karagas, Michelle Katzow, Annemarie Stroustrup, Mehtap Haktnair, Tina V Hartert, Brittney M Snyder, Sophia Jan, Anne Marie Singh, Dana Dabelea, Angela M Malek, Jennifer K Straughen, Carlos A Camargo, Miatta A Buxton, Rosalind Wright, Kecia Carroll, Keia Sanderson, Daphne Koinis Mitchell, Viren D'Sa, Christine Hockett, Anne L Dunlop, Shohreh F Farzen, Sunni L Mumford, Akram N Alshawabkeh, Hudson P Santos, Xueying Zhang, Zhongzheng Niu, Nan Ji, Carrie Breton, Donghai Liang, Catherine J Karr, Echo Cohort Consortium Mar 2026

Pre- And Postnatal Exposure To Pm2.5 And No2 And Blood Pressure In Children: Results From The Echo Cohort, Yu Ni, Andrew Law, Xingyu Gao, Adam A Szpiro, Christine T Loftus, Miranda Jones, Logan C Dearborn, Marnie F Hazlehurst, Allison R Sherris, Sindana Ilango, Kaja Z Lewinn, Nicole R Bush, Qi Zhao, Leonardo Trasande, Joseph T Flynn, Daniel A Enquobahrie, Ruby H N Nguyen, Tom O'Connor, Arpita K Vyas, Mingyu Zhang, Hooman Mirzakhani, Alison Hipwell, Anne Starling, Alicia K Peterson, Akhgar Ghassabian, Assiamira Ferrara, Judy Aschner, Scott Collingwood, Margaret R Karagas, Michelle Katzow, Annemarie Stroustrup, Mehtap Haktnair, Tina V Hartert, Brittney M Snyder, Sophia Jan, Anne Marie Singh, Dana Dabelea, Angela M Malek, Jennifer K Straughen, Carlos A Camargo, Miatta A Buxton, Rosalind Wright, Kecia Carroll, Keia Sanderson, Daphne Koinis Mitchell, Viren D'Sa, Christine Hockett, Anne L Dunlop, Shohreh F Farzen, Sunni L Mumford, Akram N Alshawabkeh, Hudson P Santos, Xueying Zhang, Zhongzheng Niu, Nan Ji, Carrie Breton, Donghai Liang, Catherine J Karr, Echo Cohort Consortium

Children’s Nutrition Research Center Staff Publications

Background: There is growing interest in understanding the link between early life exposures to ambient air pollution and childhood blood pressure; however, existing findings, largely from single site/cohort studies, are inconclusive.

Methods: We examined the association between exposures to fine particulate matter (PM2.5) and nitrogen dioxide (NO2) and blood pressure measured at age 5-12 years in 4863 U.S. children from 20 pregnancy cohorts of the NIH ECHO cohort. Point-based residential exposures were derived from spatiotemporal models with a biweekly resolution and averaged over each trimester, the whole pregnancy, and child age 0-2 years. We converted systolic (SBP) and diastolic blood …


Situation Mouse All Floxed Up: Exploring Phenotypic Abnormalities In Bdnf Floxed Mice, Marissa A. Burkman Mar 2026

Situation Mouse All Floxed Up: Exploring Phenotypic Abnormalities In Bdnf Floxed Mice, Marissa A. Burkman

All NMU Master's Theses

Animal research is a contentious topic in both the scientific and general communities.  It is essential that our animal models accurately and predictably depict intended phenotypes, necessitating careful colony monitoring and maintenance.  Volunteer animal staff in the Ottem Laboratory became concerned when mice with LoxP sites flanking the BDNF gene depicted anxiety-like behaviors such as aggression, difficulty handling, and increased agitation.  Though many studies have noted behavioral and phenotypic abnormalities related to large gene inserts, few have noted abnormalities with small gene inserts such as the 34 bp LoxP site.  Brandt (2018) performed a three-stage behavioral protocol on these mice …


The Application, Construction, And Validation Of Hidden Markov Model Profiles For Carbonic Anhydrase Enzymes, Samuel F. Kaplan Mar 2026

The Application, Construction, And Validation Of Hidden Markov Model Profiles For Carbonic Anhydrase Enzymes, Samuel F. Kaplan

Master's Theses

Carbonic anhydrases (CAs) catalyze the reversible hydration of CO2 and have evolved independently at least eight times, resulting in structurally distinct enzyme families (α, β, γ, δ, ζ, η, θ, ι). Traditional sequence alignment methods struggle to classify these convergently evolved proteins because their sequential similarity does not reliably indicate functional or evolutionary relationships. Many CA sequences in public databases are annotated generically without family assignments, and prior computational approaches have focused predominantly on the three well characterized families (α, β, γ), leaving the five recently discovered classes without robust classification tools. Family level assignment is often a prerequisite for …


Measurement And Control Of The Oxidation-Reduction Potential And Its Chemical And Sensory Consequences In Wines, William Jordan Wright Mar 2026

Measurement And Control Of The Oxidation-Reduction Potential And Its Chemical And Sensory Consequences In Wines, William Jordan Wright

Master's Theses

The oxidation-reduction potential (ORP) is a measurement thought to reflect the overall ability of a solution to oxidize or reduce substances within that solution. In wine, there is no absolute agreement as to which substances control or dominate the ORP; however, oxygen, ethanol, iron-tartrate and copper-tartrate complexes, and glutathione are suspected to play key roles, while sulfur dioxide and phenolics may act as buffers. Anecdotally, some varieties of Vitis vinifera are prone to oxidation while others are prone to reduction, though the chemical basis of this remains unclear. The following works aim to further elucidate the influence of specific chemical …


Molecular Techniques: A Project-Based Undergraduate Laboratory, Ming-Mei Chang Mar 2026

Molecular Techniques: A Project-Based Undergraduate Laboratory, Ming-Mei Chang

Milne Open Textbooks

This book can be read online at: milnepublishing.geneseo.edu/molecular-techniques

Molecular biology, examining the structures and functions of nucleic acids and proteins, is crucial to advancing biological science and improving human life, particularly in agriculture and medicine. Advances in the field can transform a crop to resist disease or uncover clues to fight illness by manipulating DNA. Techniques for molecular biology research and applications have advanced rapidly over the past decades, and undergraduates need hands-on experiences in this vital field of science. This text provides a structured approach to learning and practicing those techniques, covering DNA, RNA, and protein across five modules …


Large Language Models For Bioinformatics, Wei Ruan, Yanjun Lyu, Jing Zhang, Jiazhang Cai, Peng Shu, Yang Ge, Yao Lu, Shang Gao, Yue Wang, Peilong Wang, Lin Zhao, Tao Wang, Yufang Liu, Luyang Fang, Ziyu Liu, Zhengliang Liu, Yiwei Li, Zihao Wu, Junhao Chen, Hanqi Jiang, Yi Pan, Zhenyuan Yang, Jingyuan Chen, Shizhe Liang, Wei Zhang, Terry Ma, Yuan Dou, Jianli Zhang, Xinyu Gong, Qi Gan, Yusong Zou, Zebang Chen, Yuanxin Qian, Shuo Yu, Jin Lu, Kenan Song, Xianqiao Wang, Andrea Sikora, Gang Li, Xiang Li, Quanzheng Li, Yingfeng Wang, Lu Zhang, Yohannes Abate, Lifang He, Wenxuan Zhong, Rongjie Liu, Chao Huang, Wei Liu, Ye Shen, Ping Ma, Hongtu Zhu, Yajun Yan, Dajiang Zhu, Tianming Liu Mar 2026

Large Language Models For Bioinformatics, Wei Ruan, Yanjun Lyu, Jing Zhang, Jiazhang Cai, Peng Shu, Yang Ge, Yao Lu, Shang Gao, Yue Wang, Peilong Wang, Lin Zhao, Tao Wang, Yufang Liu, Luyang Fang, Ziyu Liu, Zhengliang Liu, Yiwei Li, Zihao Wu, Junhao Chen, Hanqi Jiang, Yi Pan, Zhenyuan Yang, Jingyuan Chen, Shizhe Liang, Wei Zhang, Terry Ma, Yuan Dou, Jianli Zhang, Xinyu Gong, Qi Gan, Yusong Zou, Zebang Chen, Yuanxin Qian, Shuo Yu, Jin Lu, Kenan Song, Xianqiao Wang, Andrea Sikora, Gang Li, Xiang Li, Quanzheng Li, Yingfeng Wang, Lu Zhang, Yohannes Abate, Lifang He, Wenxuan Zhong, Rongjie Liu, Chao Huang, Wei Liu, Ye Shen, Ping Ma, Hongtu Zhu, Yajun Yan, Dajiang Zhu, Tianming Liu

Faculty, Staff and Student Publications

With the rapid advancements in large language model technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications. This survey aims to address this need by providing a thorough review of BioLMs, focusing on their evolution, classification, and distinguishing features, alongside a detailed examination of training methodologies, datasets, and evaluation frameworks. We explore the wide-ranging applications of BioLMs in critical areas such as disease diagnosis, drug discovery, and vaccine development, highlighting their impact and transformative potential in bioinformatics. We identify key challenges and …


Spatial Profiling Reveals Distinct Molecular And Immune Evolution Of Mouse Lung Adenocarcinoma Precancers With Or Without Carcinogen Exposure, Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian-Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao-Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y Liu, Beibei Huang, Frank R Rojas, Parra Cuentas Edwin Roger, Ou Shi, Monique B Nilsson, Alissa Poteete, Khaja B Khan, Wei Lu, Luisa M Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I Wistuba, Zhubo Wei, Linghua Wang, Don L Gibbons, Ken Chen, Alexandre Reuben, Jason M Schenkel, John V Heymach, Chao Cheng, Jia Wu, Jianjun Zhang Mar 2026

Spatial Profiling Reveals Distinct Molecular And Immune Evolution Of Mouse Lung Adenocarcinoma Precancers With Or Without Carcinogen Exposure, Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian-Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao-Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y Liu, Beibei Huang, Frank R Rojas, Parra Cuentas Edwin Roger, Ou Shi, Monique B Nilsson, Alissa Poteete, Khaja B Khan, Wei Lu, Luisa M Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I Wistuba, Zhubo Wei, Linghua Wang, Don L Gibbons, Ken Chen, Alexandre Reuben, Jason M Schenkel, John V Heymach, Chao Cheng, Jia Wu, Jianjun Zhang

Faculty, Staff and Student Publications

Tumor evolution involves genetic, transcriptional, and phenotypic alterations that shape cancer cell behavior and interactions with the microenvironment. While single‐cell technologies have advanced our understanding of this process, spatial dynamics remain incompletely characterized. Here, whole‐exome sequencing (WES), imaging mass cytometry (IMC), and spatial transcriptomics (ST) were integrated to study molecular evolution and immune responses in two lung adenocarcinoma (LUAD) mouse models: a genetically engineered model (129S4/Sv‐KrasLSL‐G12D, termed 129S4 K) and a carcinogen‐induced precancer model (129S4 U). Compared to 129S4 K, 129S4 U tumors exhibited higher mutational, neoantigen but lower copy number variation (CNV) burdens at matched developmental timepoints, consistent with …


Quantifying Rate-Limiting Genetic Variation In Breast And Ovarian Tumourigenesis, Kathleen E Houlahan, Mahad Bihie, Yves Greatti, Julián Grandvallet Contreras, Daniel J Fulop, Gonzalo Lopez, Marc Williams, Hsin-Hsiung Huang, Peter Van Loo, Paul C Boutros, Kuan-Lin Huang Mar 2026

Quantifying Rate-Limiting Genetic Variation In Breast And Ovarian Tumourigenesis, Kathleen E Houlahan, Mahad Bihie, Yves Greatti, Julián Grandvallet Contreras, Daniel J Fulop, Gonzalo Lopez, Marc Williams, Hsin-Hsiung Huang, Peter Van Loo, Paul C Boutros, Kuan-Lin Huang

Faculty, Staff and Student Publications

Background: The number and type of genetic alterations required to initiate breast and ovarian cancer remain unclear. While germline BRCA1/2 carriers show markedly elevated cancer risk, it is uncertain whether point mutations or copy number alterations constitute the rate-limiting events of tumourigenesis.

Methods: We developed a statistical framework extending prior incidence-mutation models to estimate the minimal number and type of driver events required for cancer initiation. Somatic mutation and copy-number data from >3000 breast and ovarian cancers in TCGA and METABRIC were compared between germline BRCA1/2 carriers and non-carriers matched on subtypes. Results were validated through analyses of evolutionary timing …


A Comprehensive Biomechanical Material Characterization Of The Human Breast Fibro-Structural Support System, Aroj Bhattarai, Gregory P Reece, Kristy K Brock, Krishnaswamy Ravi-Chandar Mar 2026

A Comprehensive Biomechanical Material Characterization Of The Human Breast Fibro-Structural Support System, Aroj Bhattarai, Gregory P Reece, Kristy K Brock, Krishnaswamy Ravi-Chandar

Faculty, Staff and Student Publications

Breast surgery for aesthetic purposes, such as breast augmentation or breast reduction, and breast reconstruction after cancer treatment require an accurate structural (anatomical) and mechanical (functional) understanding of the breast components, including the fascial-ligamentous support system of the breast, to achieve optimal results. This paper aims to provide a comprehensive description of the mechanical behavior of the ligamentous and fascial connective tissues of the human female breast. Fasciae and ligaments obtained from 17 patients between 35 and 85 years of age who were undergoing mastectomy and three female cadavers were tested. Uniaxial tensile tests were conducted, and three constitutive models …


Assessment Of Aluminum-Based Drinking Water Treatment Residuals From Multiple Utilities In The United States As Green Sorbents For Pfas, Parisa Javidan, Roxana Rahmati, Zhiming Zhang, Anshuman Satpathy, Steven Larson, Rupali Datta, Dibyendu Sarkar Mar 2026

Assessment Of Aluminum-Based Drinking Water Treatment Residuals From Multiple Utilities In The United States As Green Sorbents For Pfas, Parisa Javidan, Roxana Rahmati, Zhiming Zhang, Anshuman Satpathy, Steven Larson, Rupali Datta, Dibyendu Sarkar

Michigan Tech Publications

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants causing human health concerns. In this study, five aluminum-based drinking water treatment residuals (Al-WTRs) were evaluated as green adsorbents for the removal of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) from water. Al-WTRs are nonhazardous solid wastes generated during the coagulation process of water treatment using aluminum salts or polymers. Although high PFAS adsorption capacity of Al-WTRs generated in one facility in the US has been reported, no study exists assessing PFAS adsorption capabilities of WTRs generated in multiple facilities using various types of aluminum coagulants. Batch adsorption experiments of PFOA …


Optimized Deep Learning Framework With H2o For Lung Cancer Prediction, Walaa Hassan Ibrahim, Mohamed S. Saraya, Sally M. Elghamrawy, Ali I. Eldesouky Feb 2026

Optimized Deep Learning Framework With H2o For Lung Cancer Prediction, Walaa Hassan Ibrahim, Mohamed S. Saraya, Sally M. Elghamrawy, Ali I. Eldesouky

Mansoura Engineering Journal

The automatic diagnosis of lung cancer using chest X-ray (CXR) images has significantly advanced with progress in computing, machine learning, and deep learning. However, detecting lesions and nodules remains challenging due to CXR limitations. Early lung cancer detection is critical for successful treatment, but current AI algorithms often rely on large annotated datasets, which are not always available. To address this, a novel multi-classification deep learning framework is proposed that combines CXR and CT images. This approach leverages the detailed feature detection capabilities of CT scans alongside the complementary views from CXRs, improving early-stage lung cancer detection and classification precision. …


Physiological And Neurological Impact Of Biophilic Design In Architectural Design Studios: A Case Study Of King Salman International University, Islam Ashraf Mohamed, Alaa El-Eishy, Marwa A. Soliman Feb 2026

Physiological And Neurological Impact Of Biophilic Design In Architectural Design Studios: A Case Study Of King Salman International University, Islam Ashraf Mohamed, Alaa El-Eishy, Marwa A. Soliman

Mansoura Engineering Journal

Biophilic design integrates nature into architecture to enrich sensory and cognitive experiences, enhance psychological well-being, and improve performance. This study explores its physiological and neural effects in design studios at King Salman International University through an experimental methodology combining theoretical review and lab-based investigation. Tools included electrocardiography (ECG) for heart rate variability (HRV), eye-tracking for visual attention, and the Self-Assessment Manikin (SAM) for emotional evaluation. Nine participants viewed five digital architectural scenes with varying biophilic integration. Direct nature connections elicited greater visual attention, pleasure, and perceived control, indicating higher engagement and relaxation.  A scene lacking biophilic elements led to reduced …


Exosome Engineering For Blocking Gut Dysbiosis And Inducing Cell Death Mechanisms In Glioblastoma Multiforme, Ahalya Muraleedharan, Karthik Rangavajhula, Swapan K. Ray Feb 2026

Exosome Engineering For Blocking Gut Dysbiosis And Inducing Cell Death Mechanisms In Glioblastoma Multiforme, Ahalya Muraleedharan, Karthik Rangavajhula, Swapan K. Ray

Faculty Publications

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor in adults. Emerging evidence endorses that gut dysbiosis contributes to GBM progression through the gut–brain axis (GBA), promoting inflammation and therapeutic resistance via abnormal short-chain fatty acid production and cytokine dysregulation. Exosomes, naturally occurring nanovesicles (30–150 nm), offer promising therapeutic potential due to their blood–brain barrier permeability, biocompatibility, and versatile cargo capacity. This review examines exosome engineering strategies for dual targeting: inhibiting alterations in gut microbiome and inducing regulated cell death mechanisms such as apoptosis and ferroptosis in GBM. We describe exosome engineering with detailed focus on cargo loading approaches …


Examining The Effect Of Different Polycarbonate Greenhouse Cover Materials On Tomato Yield And Plant Development With Thermal Imaging, Candan Korkmaz, Nefi̇se Yasemi̇n Tezcan Feb 2026

Examining The Effect Of Different Polycarbonate Greenhouse Cover Materials On Tomato Yield And Plant Development With Thermal Imaging, Candan Korkmaz, Nefi̇se Yasemi̇n Tezcan

Turkish Journal of Agriculture and Forestry

In this study, the effects of different polycarbonate (PC) greenhouse covering materials on the environmental microclimateand plant growth were examined using three research greenhouses. Two types of PC covering materials were tested: the first greenhousewas covered with UV-additive PC (UV PC), the second greenhouse with UV+Infrared (IR) additive PC (UV+IR PC), and the third(control) greenhouse had UV-additive PC on the sidewalls and polyethylene (PE) covering material (UV PC+PE) on the roof. Themeasured fundamental parameters included total radiation transmittance, photosynthetically active radiation (PAR) transmittance,temperature, and relative humidity. Plant development was monitored and leaf temperatures were measured using a thermal camera atvarious …


Bioactive Profile And Mineral Composition Of Fruit Extracts From Four Wild Hawthorn (Crataegus Spp.) Species, Özlem Çakir, Kübra Çinar Topçu, Abdurrahman Sefali, İshak Bayyi̇ği̇t, Gülçe İlhan, Jyoti̇ Singh Feb 2026

Bioactive Profile And Mineral Composition Of Fruit Extracts From Four Wild Hawthorn (Crataegus Spp.) Species, Özlem Çakir, Kübra Çinar Topçu, Abdurrahman Sefali, İshak Bayyi̇ği̇t, Gülçe İlhan, Jyoti̇ Singh

Turkish Journal of Agriculture and Forestry

This study compared the antioxidant capacity, total phenolic content (TPC), phenolic composition, lipid oxidation level, andmineral profiles of extracts obtained from four wild hawthorn species (Crataegus tanacetifolia, C. orientalis subsp. orientalis, C. orientalissubsp. szovitsii, and C. monogyna) collected from northeastern Türkiye. Significant interspecific variations were observed in DPPH,FRAP, and CUPRAC assays. While C. monogyna had the highest reducing capacity and TPC, C. orientalis subsp. szovitsii had the highestDPPH activity. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis showed that catechin,epicatechin, chlorogenic acid, and quinic acid were the major phenolics, and were particularly abundant in C. monogyna. Despitehaving a …


Functional Characteristics Of Ice Creams Enriched With Aronia Melanocarpa And Sambucus Nigra L. Extracts, Murat Emre Terzi̇oğlu, Emi̇ne Maci̇t Feb 2026

Functional Characteristics Of Ice Creams Enriched With Aronia Melanocarpa And Sambucus Nigra L. Extracts, Murat Emre Terzi̇oğlu, Emi̇ne Maci̇t

Turkish Journal of Agriculture and Forestry

In this study, the effects of Aronia melanocarpa and Sambucus nigra L. extracts added at different concentrations (0.5%, 1%,and 1.5%) on the physicochemical, sensory, microbiological, antioxidant capacity (DPPH• and ABTS•+ radical scavenging activity, TPC,TFC, and TAC) antidiabetic (α-amylase and α-glucosidase inhibition), and anti-Alzheimer properties (AChE inhibitory activity) of icecream were investigated. According to the statistical analysis results, extract addition did not have an effect on the total dry matter, fatand ash ratios of the ice cream samples (p > 0.05), but it had an effect on the protein ratio, viscosity, and first drip time at the level ofp < 0.05. The addition of extract positively affected the DPPH• radical scavenging activity IC50 and ABTS•+ radical scavenging activityIC50 values of the ice cream samples, and also increased the TPC, TFC, and TAC values. Indeed, a decrease in the IC50 values of DPPH•and ABTS•+ radical scavenging activities indicates an increase in antioxidant activity. The highest TPC, TFC, and TAC values weredetected in the A-1.5 sample (sample containing 1.5% A. melanocarpa extract) as 749.33 mg GA/kg, 434.70 mg QE/kg, and 290.97 mg/kg, respectively. Similarly, the highest α-amylase inhibitory activity (23.08%), the highest α-glucosidase inhibitory activity (10.41%) andthe highest AChE inhibitory activity (14.70%) were observed in the A-1.5 sample. Extract addition had no effect on microbiologicalproperties and sensory properties except texture. The results of this study showed that A. melanocarpa, S. nigra L. extracts can be usedas a natural additive with antioxidant, antidiabetic and anti-Alzheimer activities in ice cream production.


Towards The Assessment Of E-Flows: A Fish-Based Approach For The Tiber River Basin (Central Italy), Antonella Carosi, Francesca Lorenzoni, Fatemeh Zarei, Rachele Brustenga, Lucio Di Matteo, Daniela Valigi, Corrado Cencetti, Carlo Cardellini, Stefano Casadei, David Cappelletti, Massimo Lorenzoni Feb 2026

Towards The Assessment Of E-Flows: A Fish-Based Approach For The Tiber River Basin (Central Italy), Antonella Carosi, Francesca Lorenzoni, Fatemeh Zarei, Rachele Brustenga, Lucio Di Matteo, Daniela Valigi, Corrado Cencetti, Carlo Cardellini, Stefano Casadei, David Cappelletti, Massimo Lorenzoni

Turkish Journal of Zoology

Estimating ecological flows (EFs) in rivers is crucial for meeting the Water Framework  Directive (WFD) 2000/60/EC goals. To develop an EF model, it is  essential to use biological indicators to reliably record the impacts of human-induced  alterations on aquatic ecosystems. The adaptability of fish to annual flow variability  makes them a significant biological quality element (BQE). Consequently, using fish  as bioindicators is a powerful tool for assessing the impact of changes in the  hydrological regime on the natural communities within a river system. The new index  of the ecological status of fish communities (NISECI) is a methodology developed in  Italy …


Chlorella Vulgaris Measurements Using Full-Spectrum Goniometer For Optically Complex Inland Water Monitoring, Pinar Gürbüzer, Uğur Murat Leloğlu Feb 2026

Chlorella Vulgaris Measurements Using Full-Spectrum Goniometer For Optically Complex Inland Water Monitoring, Pinar Gürbüzer, Uğur Murat Leloğlu

Turkish Journal of Zoology

Rising environmental stressors, including climate change, nutrient loading, pollution,  and anthropogenic impacts, have made the continuous monitoring of lake water  quality increasingly essential. While in situ methods offer high precision, satellite-based remote sensing is essential for capturing large-scale, long-term changes and  accessing remote or extreme environments. To complement these approaches, we  developed a cost-effective in situ optical measurement system specifically designed  for optically complex inland waters. T he instrument enables detailed optical  characterization across scattering angles from 0° to 160° and wavelengths between  423 and 728 nm, covering both visible and near-infrared regions. Initial validation was  performed using monocultures of …


Alkaline And Acid Extraction Of An L-Tryptophan–Sunflower Flour Red Colorant: Production, Characterization, And Utilization, Spencer Nguyen, Marissa Wong, Lilian Were Senger Feb 2026

Alkaline And Acid Extraction Of An L-Tryptophan–Sunflower Flour Red Colorant: Production, Characterization, And Utilization, Spencer Nguyen, Marissa Wong, Lilian Were Senger

Food Science Faculty Articles and Research

The objective was to produce and characterize a red colorant resulting from interaction of sunflower-derived chlorogenic acid with L-tryptophan/Trp and to evaluate its applications. Yield, intensity, solubility, stability, protein, and metal content of colorants from pH 9 and pH 11 lyophilized sunflower flour- Trp colorants were measured. Red color formation took < 3 h with alkalization and subsequent acidification. The sunflower flour: Trp mixture ratio that produced the greatest redness was 10:2. The highest red pigment was in supernatants and not the precipitates. The red colorant intensity and solubility were highest at neutral pH when compared to acidic pH solutions. The color stability of the new red colorant in icing and refrigerated whole milk matrices, when assessed weekly for a month, showed no color change in refrigerated milk. After 30 min of incubation at 63 °C, pinkness in milk remained unchanged or increased. The pink color, however, faded in icing over time due to exposure to light. The present study established a new natural red colorant developed from sunflower protein-Trp mixtures at alkaline pH, as well as its application in icings and whole milk for commercial strawberry milk products. This colorant could serve as a replacement for the synthetic petroleum-based Red 3.


Changes In Metabolomics And Tissue Architectural Alterations Jointly Ameliorate Salt Mediated Injuries In Nigella Sativa L., Noreen Akhter, Ayesha Ali, Muhammad Aqeel, Muhammad Muslim Shahnaz, Saima Iqbal, Ayesha Riaz, Mohammed O. Alshahrani, Ali Noman, Noreen Khalid, Khairah M. Alwutayd Alomran, Fahad Mohamed Al-Zuibar Feb 2026

Changes In Metabolomics And Tissue Architectural Alterations Jointly Ameliorate Salt Mediated Injuries In Nigella Sativa L., Noreen Akhter, Ayesha Ali, Muhammad Aqeel, Muhammad Muslim Shahnaz, Saima Iqbal, Ayesha Riaz, Mohammed O. Alshahrani, Ali Noman, Noreen Khalid, Khairah M. Alwutayd Alomran, Fahad Mohamed Al-Zuibar

Turkish Journal of Agriculture and Forestry

This study evaluated plant resistance to salinity across varying salt concentrations: 0, 50, 100, 150, and 200 mM NaCl. Thestudy revealed how these salt levels affected the morphological, physiological, biochemical, and developmental characteristics of theplants. At the 50 mM NaCl treatment level, plant height dropped by 8% in comparison to the control. The shoot fresh and dry weightsof every plant subjected to different levels of salt stress decreased noticeably. At 200 mM NaCl, the plants fresh weight of root decreasedby the greatest percentage (42.8%). The total number of chlorophyll a and chlorophyll b in Nigella sativa L. was significantly lower …


Rapid Single-Cell Measurement Of Transient Transmembrane Water Flow Under Osmotic Gradient, Hong Jiang, Jinnawat Jongkhumkrong, Y. J. Chao, Qian Wang, Guiren Wang Feb 2026

Rapid Single-Cell Measurement Of Transient Transmembrane Water Flow Under Osmotic Gradient, Hong Jiang, Jinnawat Jongkhumkrong, Y. J. Chao, Qian Wang, Guiren Wang

Faculty Publications

Aquaporins (AQPs) are critical for transmembrane water transport in response to osmotic gradients, but their gating and regulatory mechanisms remain poorly understood. A central challenge is the lack of methods to measure water flow across AQPs from individual cells with the spatiotemporal resolution and sensitivity equivalent to patch-clamp recordings of ion fluxes—a limitation stemming from the electrically silent nature of water flow. Here, we present a novel optical technique—Flow-Induced Fluorescence Increase Velocimetry (FIFIV) based on Laser-Induced Fluorescence Photobleaching Anemometry (LIFPA)—that enables direct, real-time monitoring of cytoplasmic flow induced by transmembrane water transport under osmotic pressure gradients. Using small molecular fluorescent …


Chrysin Alleviates Salt Stress By Enhancing Antioxidant Enzymes, Nutrient Balance, And Phytohormone Contents In Forage Pea, Sedat Severoğlu Feb 2026

Chrysin Alleviates Salt Stress By Enhancing Antioxidant Enzymes, Nutrient Balance, And Phytohormone Contents In Forage Pea, Sedat Severoğlu

Turkish Journal of Agriculture and Forestry

This study aimed to evaluate the potential protective effects of chrysin (Chr), a flavonoid compound, on growth, biochemical,hormonal, and nutrient levels in forage pea (Pisum sativum ssp. arvense L.) seedlings under NaCl-induced salt stress. The experimentwas conducted under controlled greenhouse conditions in a completely randomized design with three different concentrations of Chr(Chr0: 0 mM, Chr1: 0.1 mM, and Chr2: 0.5 mM Chr) and three levels of salt stress (S0: 0 mM, S1: 100 mM, and S2: 200 mM NaCl),resulting in nine treatment combinations (T0: Chr0S0, T1: Chr0S1, T2: Chr0S2, T3: Chr1S0, T4: Chr1S1, T5: Chr1S2, T6: Chr2S0, T7: Chr2S1, andT8: …


Effects Of Gamma Irradiation On Antioxidant Enzyme Activities In Black Carrot Callus Under Drought Stress, Damla Turan Büyükdi̇nç, Di̇lruba Tabay Sümbül, Sheikh Mansoor Feb 2026

Effects Of Gamma Irradiation On Antioxidant Enzyme Activities In Black Carrot Callus Under Drought Stress, Damla Turan Büyükdi̇nç, Di̇lruba Tabay Sümbül, Sheikh Mansoor

Turkish Journal of Agriculture and Forestry

Daucus carota L. (carrot) is a commercially significant root vegetable widely cultivated in temperate regions for its edible taproot and valued for its high nutritional content. This study aimed to investigate the effects of drought stress on callus tissues of the Hatay black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) genotype and to determine the impact of different gamma radiation doses on antioxidant enzyme activities. Black carrot callus tissues were exposed to gamma irradiation at doses of 0, 7, 8, and 9 Gy to evaluate their responses to drought stress. Antioxidant enzyme activities, including superoxide dismutase (SOD), …


Production Of The Antitumor Compound Deoxyharringtonine By Suspension-Culturedcells Of Cephalotaxus Hainanensis, Liang Wang, Muhammad Mubashar Zafar, Chongyu Wu, Zhiqiang Xiong, Jingyi Sun, Huapeng Sun, Hanqing Cong, Xuefei Jiang, Mahmoud F. Seleiman, Fei Qiao, Peter Nick Feb 2026

Production Of The Antitumor Compound Deoxyharringtonine By Suspension-Culturedcells Of Cephalotaxus Hainanensis, Liang Wang, Muhammad Mubashar Zafar, Chongyu Wu, Zhiqiang Xiong, Jingyi Sun, Huapeng Sun, Hanqing Cong, Xuefei Jiang, Mahmoud F. Seleiman, Fei Qiao, Peter Nick

Turkish Journal of Agriculture and Forestry

Plant cell fermentation can be a sustainable biotechnological alternative to the wild collection of medicinal plants. As aparadigm, we explored the potential of using the highly endangered endemic tree Cephalotaxus hainanensis, which accumulatescephalotaxine esters—potent anticancer compounds. We successfully established a suspension cell line able to convert cephalotaxineinto its esters, including deoxyharringtonine, harringtonine, isoharringtonine and homoharringtonine at a remarkable maximalconversion rate of up to 86%, when supplemented with L-homoleucine, a precursor for the side chains of these esters. Furthermore, byadding elicitors, we were able to enhance the yield significantly beyond the values expected from the complete conversion of the addedcephalotaxine. In …


Effectiveness Of A Network Open House Model To Recruit Trainees To Post-Baccalaureate Stem Programs, Sarah Mordan-Mccombs, Scott Takeo Aoki, Lindsay Lewellyn, Sarah Justice, Neetu Tewari, Jorge Cantu, Robert Seiser, Ahmed Lakhani, Jennifer R. Kowalski Feb 2026

Effectiveness Of A Network Open House Model To Recruit Trainees To Post-Baccalaureate Stem Programs, Sarah Mordan-Mccombs, Scott Takeo Aoki, Lindsay Lewellyn, Sarah Justice, Neetu Tewari, Jorge Cantu, Robert Seiser, Ahmed Lakhani, Jennifer R. Kowalski

Biology Faculty publications

Post-baccalaureate (post-bac) programs can be instrumental in strengthening science training and expanding STEM career opportunities for junior trainees. Many of these sponsored programs are designed to increase research exposure for underrepresented minorities, including African American, Hispanic, Native American, and first-generation college students, among others. Recruiting trainees to post-bac programs can be challenging for reasons including a lack of awareness about available programs. To address this gap, an Open House event was created with the goal of raising awareness and generating interest among potential students for future post-bac programs. Students were recruited from partnering Minority Serving Institutions (MSIs) to attend a …


Comparison Of The Mars And Xgboost Algorithms For Predicting Body Weight In Kalahari Red Goats, Louis Thobela Tyasi, Cem Tirink, Kwena Mokoena, Hasan Önder, Uğur Şen, Demet Çanga Boğa, Tolga Tolun, İsmai̇l Gök, Yüksel Aksoy, Lütfi̇ Bayyurt, Ömer Faruk Yilmaz Feb 2026

Comparison Of The Mars And Xgboost Algorithms For Predicting Body Weight In Kalahari Red Goats, Louis Thobela Tyasi, Cem Tirink, Kwena Mokoena, Hasan Önder, Uğur Şen, Demet Çanga Boğa, Tolga Tolun, İsmai̇l Gök, Yüksel Aksoy, Lütfi̇ Bayyurt, Ömer Faruk Yilmaz

Turkish Journal of Veterinary & Animal Sciences

Estimating goat body weight from morphometric traits is essential for growth monitoring, health management, and welfare. Accurate weight informs nutrition, clinical interventions, and mating decisions. In this study, the MARS and XGBoost algorithms were used to estimate the live weight of Kalahari Red goats based on body measurements. A dataset containing body length (BL), birth type (single, twin, or triplet), withers height (WH), rump height (RH), and heart girth (HG) information for 200 goats was used in the training and testing of the models. The performances of the models were evaluated with the goodness-of-fit criteria. XGBoost showed a performance of …


Effects Of Functional Ankle Instability On Muscle Activation Latency In Ice Hockey Athletes: A Pilot Study, Nicolas Gonzalez, Tyler A. Wood, Nicholas E. Grahovec Feb 2026

Effects Of Functional Ankle Instability On Muscle Activation Latency In Ice Hockey Athletes: A Pilot Study, Nicolas Gonzalez, Tyler A. Wood, Nicholas E. Grahovec

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

This study examined lower extremity muscle activation latency during the push-off phase in ice hockey athletes with and without functional ankle instability (FAI). Ten athletes participated, divided into FAI and control groups based on the Identification of Functional Ankle Instability scale. Participants completed three push-off trials while wearing electromyography sensors on the tibialis anterior, fibularis longus, medial gastrocnemius, and gluteus medius. The FAI group demonstrated a significant increase in muscle activation latency across all muscles tested (p