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Articles 49441 - 49444 of 49444

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The Eastern Mail (Vol. 01, No. 13): October 21, 1847, Ephraim Maxham Oct 1847

The Eastern Mail (Vol. 01, No. 13): October 21, 1847, Ephraim Maxham

The Eastern Mail (Waterville, Maine)

Continues The Waterville Union (April-July 1847).
Published weekly, July 19, 1847-Aug. 28, 1863.
Publishers: E. Maxham, 1847-1849; Maxham & Wing, 1849-1863.
"Independent," 1847-1856; "Republican," 1856-1863.
Editors: E. Maxham & D.R. Wing, 1849-1863.
Continued by The Waterville Mail (September 1863-May 1906).
See Gerould, W.G.: American newspapers, 1821-1836; Whittemore, E.C.: Centennial history of Waterville.
Colby Libraries catalog record (CBBcat): http://cbbcat.net/record=b1228542~S19
WorldCat record (OCLC): http://www.worldcat.org/oclc/10486915

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The Eastern Mail (Vol. 01, No. 10): September 30, 1847, Ephraim Maxham Sep 1847

The Eastern Mail (Vol. 01, No. 10): September 30, 1847, Ephraim Maxham

The Eastern Mail (Waterville, Maine)

Continues The Waterville Union (April-July 1847).
Published weekly, July 19, 1847-Aug. 28, 1863.
Publishers: E. Maxham, 1847-1849; Maxham & Wing, 1849-1863.
"Independent," 1847-1856; "Republican," 1856-1863.
Editors: E. Maxham & D.R. Wing, 1849-1863.
Continued by The Waterville Mail (September 1863-May 1906).
See Gerould, W.G.: American newspapers, 1821-1836; Whittemore, E.C.: Centennial history of Waterville.
Colby Libraries catalog record (CBBcat): http://cbbcat.net/record=b1228542~S19
WorldCat record (OCLC): http://www.worldcat.org/oclc/10486915

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The Eastern Mail (Vol. 01, No. 08): September 16, 1847, Ephraim Maxham Sep 1847

The Eastern Mail (Vol. 01, No. 08): September 16, 1847, Ephraim Maxham

The Eastern Mail (Waterville, Maine)

Continues The Waterville Union (April-July 1847).
Published weekly, July 19, 1847-Aug. 28, 1863.
Publishers: E. Maxham, 1847-1849; Maxham & Wing, 1849-1863.
"Independent," 1847-1856; "Republican," 1856-1863.
Editors: E. Maxham & D.R. Wing, 1849-1863.
Continued by The Waterville Mail (September 1863-May 1906).
See Gerould, W.G.: American newspapers, 1821-1836; Whittemore, E.C.: Centennial history of Waterville.
Colby Libraries catalog record (CBBcat): http://cbbcat.net/record=b1228542~S19
WorldCat record (OCLC): http://www.worldcat.org/oclc/10486915

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Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry Dec 200

Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication but avoid production of infectious virions, we developed “single-cycle” adenovirus (SC-Ad) vectors. Previous work demonstrated that SC-Ads amplify transgene expression 100-fold and produce markedly stronger and more persistent immune responses than RD-Ad vectors …

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