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Sulphur Metabolism As A Key Factor In The Evolution Of Environmental Adaptation Of Acidihalobacter, Eva Vergara, Himel Nahreen Khaleque, Gonzalo Neira, Elizabeth L.J. Watkin, Jorge H. Valdés, David S. Holmes

Research outputs 2022 to 2026

This study compares predicted sulphur metabolism genes across four Acidihalobacter type strains and two metagenome-assembled genomes (MAGs), revealing genomic differences that appear to correspond to ecological specialization. Phylog-enomic analysis separates the species into two clades: clade I includes Acidihalobacter ferrooxydans from a geothermal region in Italy and the two MAGs derived from deep-sea hydrothermal vents in the Pacific Ocean, while clade II comprises Acidihalo-bacter aeolianus and Acidihalobacter prosperus from a geothermal region in Italy and Acidihalobacter yilgarnensis from a saline and acidic drainage in Australia. Variations in sulphide/quinone oxidoreductases (SQRs) across the species, in particular in Ah. ferrooxydans and Ah. …

Toxicology Case Study Model, Ana Pego

Open Educational Resources

Graduate students apply laboratory skills to an authentic forensic toxicology case by interpreting evidence, recommending analytical methods, and presenting a critical group assessment.

Assessing Fisheries Dependence Of Coastal Communities In Managed Mangrove Forests In Latin America, Ariel Alexander Quintanilla Magana

Open Access Dissertations

Fisheries dependency refers to the action of a person, community, or society linking their social, cultural, and economic actions to different ecosystem services (ES) for covering their food system with essential marine species, developing a governance system to conserve these fishing areas, their local ecological knowledge, and guaranteeing food security in the coastal areas. In Latin America, most fishing activities are practiced within three nautical miles of the shoreline, estuaries, lagoons, and mangrove forest channels, using small vessels and traditional gear such as hooks, trammel nets, and gill nets. Some coastal communities have developed their subsistence and livelihood activities in …

Effects Of Desiccation On Invasive Faucet Snail (Bithynia Tentaculata) And Trematode Survival, Elise Marie Jordahl

Graduate Research Theses & Dissertations

Parasitism is one of the most common and diverse life history strategies, yet relatively little is known about the role of parasites as invasive species. Invasive species, which present one of the greatest threats to biodiversity, often need to overcome adverse environmental conditions as they establish and spread in new habitats. Invasive parasites are subject to these same conditions, though the effects may be mediated through their hosts. Here, I use an invasive snail and its trematode parasites to quantify the effects of desiccation on survival to better understand how processes of invasion play out in host-parasite systems. The faucet …

Photovoice Exploration Of Afghan Refugee Background Women's Food-Related Well-Being, Eileen C. Lindemann

Graduate Research Theses & Dissertations

More than 117,000 Afghans have been relocated to the United States following the U.S. military withdrawal in August 2021. Research indicates that Afghan refugees resettled in the U.S. are at increased risk of psychological distress, with Afghan women particularly susceptible compared with Afghan men, and diet-related chronic disease. However, research also shows that traditional food and eating customs foster cultural identity, social support, integration, and well-being. The purpose of this study was to collaboratively explore the food-related well-being and daily life contexts of resettled refugee participants through the photovoice method, a participatory research strategy in which participants photograph aspects of …

Regenerative Farming Practices Effects On Invertebrates In Wheat Systems, Daniel J. Pecenka

Electronic Theses and Dissertations

The modern agricultural system is based upon the Green Revolutions principle of creating more food. However, this came at a cost of invertebrate declines through habitat loss, pollution, and the introduction of agrochemicals. Here I address knowledge gaps in biological inventory of invertebrates across north, northwestern, and central North America. These invertebrates were identified and given a size scale and a dietary guild. We also examined how regenerative and conventional agricultural practices can affect invertebrate populations within the same crop. We also examined whether regenerative management wheat fields fostered great invertebrate communities while limited pest presence. Invertebrate populations were negatively …

Prepregnancy Overweight And Obesity In Kuwait Birth Cohort Study, Abdullah Al-Taiar, Ali H. Ziyab, Eelaf A. Husain, Maryam M.Y. Mohammad, Maryem A. Shamsah, Noor Salah Alali, Reem Sharaf-Alddin, Majeda S. Hammoud

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Objectives: This study aimed to estimate the prevalence of prepregnancy obesity and overweight, and to identify a set of sociodemographic factors that could guide weight management interventions for women prior to conception.

Design, Sample, and Measurements: Pregnant women (N = 989) were recruited in the Kuwait Birth Cohort Study during the period June 2017 to February 2020. Prepregnancy weight and height were self-reported, while current weight and height were measured in a standardized procedure. Data on sociodemographic factors were collected through face-to-face interviews conducted by a trained data collector. Multinomial logistic regression was used to investigate the association between sociodemographic …

A Critical Perspective On The Society Of Environmental Toxicology And Chemistry's Adherence To Founding Principles— Opportunities For The Future, Barnett A. Rattner, Annegaaike Leopold, Carys L. Mitchelmore, Glenn W. Suter, Mark S. Johnson, Adriana C. Bejarano, Lawrence A. Kapustka, Niranjana Krishnan, Derek C. G. Muir, Beatrice O. Opeolu, Martha Georgina Orozco-Medina, April Reed, Bruce W. Vigon, Adam R. Wronski

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

The Society of Environmental Toxicology and Chemistry (SETAC) is a global organization whose mission is the advancement of environmental science and management through collaboration, leadership, communication and education. On SETAC's 45th anniversary, the following question was raised: Are the 1979 founding principles of SETAC, multidisciplinary approaches to solving environmental problems, multisector engagement and scientific objectivity, still useful, adequate and effective in fulfilling its mission? In a special session held at the 45th Annual Meeting in Fort Worth, Texas, United States, a critical evaluation of the founding principles was initiated by reviewing SETAC's history and ongoing activities, and recommendations were made …

The Geminivirus Al2 Protein Interacts With Host Proteins Involved In The Plant Antiviral Response, Pheobean Atieno Odongo

Graduate Research Theses & Dissertations

Geminiviruses are economically important plant DNA viruses infecting a broad range of plant species and causing devastating crop diseases, resulting in up to 100% crop loss. As a result of these heavy losses on food and cash crops, these viruses represent a new threat to global food security and sustainability. In this research, I use Tomato golden mosaic virus (TGMV) to study host-virus relationships with an overall goal of developing sustainable and eco-friendly crop resistance. TGMV belongs to the Geminivirus subgroup, Begomovirus, that is characterized by a split genome consisting of two single-stranded circular DNAs. The TGMV genome encodes proteins …

Management-Driven Shifts In The Bison Fecal Microbiome And Its Relationship To Stec Prevalence, Ritesh Ray

Graduate Research Theses & Dissertations

Contamination of meat samples from pathogens such as Shiga toxin-producing E. coli (STEC), especially in ruminants, is an ever-growing issue for the safety of global meat production. Recent studies have reported STEC in the livestock and food industry with a limited focus on wildlife. Although cattle serve as the primary reservoir for STEC, American bison (Bison bison bison) is the largest ruminant inhabiting North America, sharing similar genetics, and grazing habits, making them an ideal alternative STEC reservoir. Re-introduction for prairie conservation and meat farming has brought bison herds closer to anthropic environments than before. Recently bison meat has become …

Velocity Based Training In Athletic Development, Ross Martin Sangalang

Graduate Student Theses, Dissertations, & Professional Papers

The foundation of high-level sport performance is the ability to produce and express force rapidly across the task-specific temporal demands of sport. Traditional percentage-based prescription methods have long been used to develop hypertrophy, maximal strength, and power; however, fixed %1RM prescriptions fail to account for daily undulations in athlete readiness, accumulated fatigue, and changes in neuromuscular capacity. Velocity based training (VBT) offers a practical framework to regulate training through measurement of concentric velocity, allowing coaches to more accurately prescribe loads, stringently monitor repetition quality, and precisely regulate fatigue. This review discusses the neuromuscular qualities underpinning success in athletic endeavors, limitations …

A Review Of Mockingbird Song, Jacqueline Milander

Student Theses

The northern mockingbird (Mimus polyglottos) is known for its large repertoire and highly versatile song patterns.  It is a frequent mimic that is thought to continue learning sounds from its environment for the duration of its life.  Utilizing available song studies, this is a comprehensive review of northern mockingbird song, including learning, mimicry, repertoires, song dependence on seasonal cyclicity, and song function, particularly interspecific territoriality. While much discussion has surrounded the idea that northern mockingbirds engage in interspecific territoriality and that vocal mimicry functions in intersexual selection, this review provides new insight into the possibility that latitudinal differences among populations …

A Generalized Framework For The “Core” Thalamocortical Circuit Computation, Charles Liu

Dartmouth College Ph.D Dissertations

This thesis explores a biologically inspired computational framework based on a common excitatory-inhibitory circuit in the superficial layers of the cortex. By varying the strength of local feedback inhibition, this single circuit gives rise to distinct unsupervised learning behaviors: strong inhibition leads to clustering and hierarchical clustering, while weak inhibition produces principal component-like representations. From this principle, we develop three algorithms: Lateral Inhibition Clustering (LI-C), Lateral Inhibition Hierarchical Clustering (LI-HC), and Antipodal Iterative Mean Estimation (AIME).

LI-C performs clustering without requiring a predefined number of clusters, using a competitive learning rule to extract dominant patterns from data. LI-HC extends this …

Characterization Of The Effects Of Atp On Primary Brainstem Glial Cells, Donovan J. Aardema Faigh

Graduate Theses/Dissertations

Migraine and temporomandibular joint disorder (TMD) are debilitating orofacial pain disorders that negatively impact one’s quality of life. These disorders are characterized by elevated levels of adenosine triphosphate (ATP) and activation of central nervous system glial cells that promote and maintain central sensitization and enhance pain signaling in response to inflammatory stimuli. The goal of my study was to characterize the effects of the pro-inflammatory signaling molecule adenosine triphosphate (ATP) on intracellular calcium levels, mRNA levels, and protein expression in astrocytes, microglia, and oligodendrocytes to better understand the role of ATP in promoting central sensitization. To address this goal, primary …

Genomic Signatures Of Decline And Recovery In An Endangered Bat, Myotis Grisescens, Marxe Altman-Orbach

Graduate Theses/Dissertations

Tremendous population declines may result in the loss of genetic diversity, which can, in turn, lead to reduced adaptive potential, overexpression of deleterious phenotypes, and further population declines. In this way, genetic drift from a severe demographic decline may ultimately lead to an extinction vortex. However, populations that avoid the loss of genetic diversity may remain viable, despite demographic crashes. Therefore, understanding genetic diversity is vital for assessing the conservation status of species that have undergone declines, and can even reflect the effectiveness of management actions. I investigated signatures of genetic bottlenecks in the gray bat (Myotis grisescens), …

United States Mainstream Meat Market Entry: An Analysis On Speciality Goat Meat Products, Madison Raye Schmitz

Graduate Theses/Dissertations

Understanding consumers' perspectives and motivations is key when looking into making goat meat more accepted in the mainstream meat market. Previous research has shown there is a demand for goat meat from different populations in the US. Consumers also care more about the quality of the food they purchase. Understanding that goat meat has lower cholesterol and is leaner than other red meat is important to incorporating goat meat in niche consumer markets. Providing consumers with a product that is familiar to them is more acceptable than giving consumers a cut of meat they are unfamiliar with. Standard products like …

Exploring Factors Mediating White-Nose Syndrome In Little Brown Bats, Carly R. Trujillo

Graduate Theses/Dissertations

The little brown bat (Myotis lucifugus) has experienced drastic population declines across North America due to the recent disease white-nose syndrome (WNS). Previous studies have identified putatively adaptive alleles (PAAs) that may give individuals a greater likelihood of survival. However, there could be geographic-specific adaptation, creating different adaptive landscapes. Additionally, there may be energetic trade-offs between disease survival and reproductive output, and it is not clear what the long-term survival outcomes for the species may be as a result. Long-term evolutionary outcomes are unclear because this species has a lifespan exceeding the arrival of WNS and is difficult …

The Effect Of Sex On A-To-I Editing In Skeletal Muscle During Inflammation, Skyler Lee

Graduate Theses/Dissertations

Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional mechanism mediated by ADAR enzymes that can alter RNA sequence, protein function, and gene regulation. Because ADAR1 is upregulated during inflammation and plays a critical role in innate immunity, previous studies investigated the effects of acute inflammation on RNA editing in male and female mice. Lipopolysaccharide (LPS) was used to induce inflammation, and RNA editing levels were examined in the heart, brain, and skeletal muscle. While editing levels in the heart and brain remained unchanged, skeletal muscle exhibited tissue- and sex-specific differences in editing. In this thesis, LPS treatment affected selective editing, increasing …

'I Want To Learn Biology And Preserve My Culture' Testing The Efficacy Of A Culturally Relevant And Context Specific Approach, Umar Adam, Musa Adekunle Ayanwale, Hafsat Mustapha, Sakibu Olajide Saibu, Tunde Owolabi, Adekunle Ibrahim Oladejo

Teaching & Learning Faculty Publications

Background

The dominance of Western-inspired teaching methods and instructional materials has contributed to cultural erosion in African schools. In response, increasing attention has been directed toward culturally responsive approaches to decolonising science education. One such approach is the Culturo-Techno-Contextual Approach (CTCA), which enables African students to conceptualize science as culturally embedded knowledge, integrated into their everyday experiences and practically relevant to their lived realities.

Purpose

This study examined the potency of the CTCA in enhancing students' achievement in the biology topic of variation, which is widely regarded as conceptually challenging.

Sample

The study involved 105 Senior Secondary II students from …

If You Build It, Will They Stay? Fish Communities Continue To Utilize Restored Habitat A Decade Following An Instream Restoration, Alexis L. Vandenberg

Masters Theses

Lotic ecosystems are degraded at an alarming rate due to anthropogenic activities. In order to combat these changes, stream restorations are implemented to improve conditions such as water quality, habitat heterogeneity, and bank stability. However, the impacts of these restorations are often understudied and long-term impacts are unknown. Restorations are typically designed to be ‘fish attractors’; this idea is known as the ‘Field of Dreams hypothesis’ – ‘if you build it, they will come’. This study uses data collected in Kickapoo Creek, Coles County from 2009 to 2015 and again in 2021 and 2022 to assess the long-term impacts of …

Compositional And Functional Shifts In Fish Community Structure In Response To Low-Head Dam Removals, Joshua D. Bruegge

Masters Theses

Low-head dams serve as intermittent barriers to aquatic connectivity and directly alter both upstream and downstream habitats and biotic communities. In 2018 and 2019, two low-head dams in the Vermilion River watershed of eastern Illinois were removed, reconnecting over 1,700 kilometers of upstream habitat within the basin. To determine the impacts of these dam removals, fish community surveys were conducted at 12 fixed sites across three reaches in two rivers from 2012-2022. This study assessed reach-specific temporal responses of the fish community and habitat characteristics. I linked trait expressions within the fish community to abiotic variables using the co-inertia RLQ …

Data For Forthcoming Article: "Employing Zebrafish To Understand Genetic Drivers Of Epilepsy-Related Comorbid Behaviors", Colleen Carpenter-Swanson

Biology Faculty Publications

Forthcoming from Frontiers in Pharmacology:

"Children with epilepsy frequently experience a range of significant comorbidities beyond seizures, such as motor dysfunction, cognitive impairment, and neurodevelopmental delays. In some cases, these comorbidities contribute more significantly to overall disease burden than the seizures themselves. To improve quality-of-life (QOL) for these children, treatment options should be selected that control seizures and ameliorate comorbidities. Unfortunately, such therapeutics remain largely elusive. Addressing this issue requires suitable preclinical models. Here we used CRISPR-generated zebrafish with single-gene mutations linked to pediatric epilepsy and applied clinically-relevant behavioral assays to study the effects of these mutations. Using high-throughput locomotion-based …

Impact Of Preoperative Symptom Duration On Postoperative Outcomes Following Lumbar Spine Surgery, Ahmed Anas Zahra, Ayman Mohamed Basha

Mansoura Medical Journal

Background: The optimal timing for lumbar spine surgery (LSS) relative to symptom duration remains debatable. While surgical delays are common, their impact on postoperative outcomes is not fully elucidated. This study evaluated the relationship between preoperative symptom duration and postoperative outcomes following LSS.

Methods: A prospective observational study was conducted on 60 adults undergoing LSS (decompression and/or fusion) at a single university hospital. Participants were stratified into three groups based on symptom duration:Months, 3-12 months, and >12 months. The primary outcome was functional disability assessed by the Oswestry Disability Index (ODI). Secondary outcomes included pain intensity (Visual Analog Scale, VAS), …

Fetal Foot Length As A Predictor Of Gestational Age, Ruman Bashir Abdi Kadie, Hossam El-Dyn El-Sayed Gouda, Mohamad Ahmad El-Sayed Mohamad Emam, Alhussein Ahmed Mohamed

Mansoura Medical Journal

Background: Accurate estimation of gestational age (GA) is essential for obstetric care. Conventional ultrasound (US) biometric parameters may be limited in certain clinical situations. Fetal foot length (FFL) has been proposed as an alternative measurement, but its role requires further evaluation.

Aim of study: To examine the association between fetal foot length and ultrasound-based gestational age, and to explore its relationship with other fetal biometric parameters in uncomplicated singleton pregnancies.

Methods: This cross-sectional study included 200 pregnant women who underwent two-dimensional transabdominal ultrasound. Standard fetal biometric parameters—including biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur length …

“Thou Hast Taught Me, Silent River, Many A Lesson, Deep And Long”: Metabolism, Development, And Evolution As Team Sports, Scott F. Gilbert

Biology Faculty Works

We recognize three great fluxes in nature. First there is the metabolic flow of molecules that pervades our cells and which creates organisms. Second, there is the developmental flow of cells that is our cycle of life. Third, there is the evolutionary flow of genes, organisms, and populations from the first single-celled prokaryotes to the extensive biodiversity present on earth today. Recent studies have shown that organisms are consortia of several species acting together. What we had thought of as metabolism based on a single genome is actually the co-metabolism of more than one species. What we had thought as …

Signs Of Life: Interkingdom Communication And The Sympoietic Organism, Scott F. Gilbert

Biology Faculty Works

No abstract provided.

Analyzing Changes In Russian Olive Distributions Along The Missouri River In Response To Flooding, Zachary Schild

Dissertations and Theses

Russian olive (Elaeagnus angustifolia; RO) is an invasive, nitrogen-fixing tree that has spread across riparian ecosystems in the western United States, potentially hindering native tree recruitment, reducing species richness, and impacting wildlife. RO has established within the Missouri National Recreational River (MNRR) in part due to modified flow regimes following dam construction. This study aimed to map the spread of RO using high-resolution National Agriculture Imagery Program (NAIP) imagery (2010, 2012, 2018, 2022) and evaluate the effects of the 2011 and 2019 floods on RO distributions in the Missouri National Recreational River (MNRR). RO cover in this area has expanded …

The Diagnostic Value Of Serum Ferritin In Telogen Effluvium, Sara Khaled Mohamed Elbasiouny, Marwa H. Elnagdy, Sherif R. Ismaeil, Fawzia A. Saafan

Mansoura Medical Journal

Background Telogen effluvium (TE) is a common cause of hair loss (HL) in females, characterized by diffuse HL. Iron deficiency has a significant relationship with emotional stress, and anxiety is another prevalent cause for HL. So, our aim was to evaluate the serum ferritin levels among TE patients, compared to healthy controls. Methods This case-control study was conducted on 100 subjects, and they were divided into 2 groups, group (A) included 50 patients with Telogen Effluvium and group (B) included 50 healthy normal volunteers matching for age and sex with the patients. Clinical examination of diffuse shedding and positive pull …

Evaluation Of Neutrophils To Albumin Ratio (Nar) And C-Reactive Protein To Albumin Ratio (Car) As Markers Of Disease Activity In Patients With Ulcerative Colitis, Doaa Salah Abd-El-Fattah, Mohamed Abd El-Maksoud, Salwa M. Abo El-Khair, Ahmed El-Eraky, Amany Hasson

Mansoura Medical Journal

Background Ulcerative colitis (UC) is considered an extensive disease due to the risks of proximal extension, malignant transformation, disability and impaired life quality. This study aimed to explore the role of Neutrophils to Albumin Ratio (NAR) and C - reactive protein to Albumin Ratio (CAR) in evaluation of disease activity in patients with UC. Methods This cross-sectional study included 227subjects classified into two groups; group (I) included 126patients suffering from ulcerative colitis and group (II) included 101 healthy individuals with normal basic laboratory tests matched for age and sex. Estimating disease activity and severity clinically was according to Truelove criteria. …

Chronic Stress And Toxoplasma Gondii Infection: Investigating The Two-Hit Hypothesis On Behavior And Cognition In Chronic Toxoplasmosis Mice Model, Nora Labeeb El-Tantawy

Mansoura Medical Journal

Background: Toxoplasmagondii infects about one third of people around the world and is associated with neuropsychiatric disorders. But not everyone who has it ends up with behavioral symptoms, which is kind of interesting. The study aimed to investigate the two-hit hypothesis, basically testing if chronic stress makes the effects of the infection worse in mice, on behavior and cognition. Methods: Sixty Swiss Webster mice were included in the study divided into four groups (15 for each). Group 1 control, group 2 stressed animals exposed to the chronic unpredictable stress protocol, Group 3 infected with T. gondii, and group 4 received …