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Full-Text Articles in Entire DC Network
The Spatiotemporal Dynamics Of Nomadic Behavior In The Clonal Raider Ant, Ooceraea Biroi, Dennis Octavio Melendez
The Spatiotemporal Dynamics Of Nomadic Behavior In The Clonal Raider Ant, Ooceraea Biroi, Dennis Octavio Melendez
Student Theses and Dissertations
Nest relocation is integral to the lives of many social insects. Army ants have taken this behavior to the extreme, with many species relocating an entire colony of over 100,000 ants plus brood almost daily. Despite its prevalence, the question of how army ant colonies emigrate has been debated for many decades, and still awaits a definitive answer because conducting well-controlled field experiments with their massive and aggressive colonies is challenging. In ants, the Dorylinae subfamily has given rise to most known army ants. Therefore, performing experiments in non-army ant dorylines that can be maintained in a laboratory setting presents …
Serotonin-Mediated Sickness Behavior, Audrey Harnagel
Serotonin-Mediated Sickness Behavior, Audrey Harnagel
Student Theses and Dissertations
Serotonin is an ancient and powerful neuromodulator that regulates diverse processes from fundamental physiology to complex emotions. Due to the many functions of serotonin distributed throughout the body and brain, governing principles of serotonin signaling have remained elusive. There is particular interest in how serotonin modulates internal states given that serotonin dysregulation is a feature of many psychiatric diseases. In this thesis, I use the simplified serotonergic system of C. elegans to explore how serotonin governs the internal state of sickness. In addition to activating the immune system and remodeling physiology, pathogenic infection results in adaptive behavioral changes that promote …
Towards Models Mesoscale Chromatin Structure And Radiative Dna Damage Via Computational Simulation, Devany Walsh West
Towards Models Mesoscale Chromatin Structure And Radiative Dna Damage Via Computational Simulation, Devany Walsh West
Student Theses and Dissertations
The spatial organization of chromatin fiber at the level of several nucleosomes–the mesoscale–is an area of active study. Recent results have shown that it differs between functional states, affects higher orders of chromosome organization, and is likely involved in transcriptional control. However, the heterogeneity of nucleosome positioning and histone variant composition in cells as well as the high density of chromatin in situ make the mesoscale difficult to study. Recent methodological advances have made it possible to derive nucleosome-resolution three-dimensional contact information directly from cells. We therefore sought to develop a structural inference tool for inferring mesoscale chromatin structures consistent …
Gpcr To Channel Communication In A Membrane Signaling Pathway, Yuxi Zhang
Gpcr To Channel Communication In A Membrane Signaling Pathway, Yuxi Zhang
Student Theses and Dissertations
G-protein-coupled receptors (GPCRs) regulate a variety of downstream effector proteins, making them essential for many physiological processes. For example, in the heart, the activation of beta-adrenergic receptors (βARs) and the stimulatory G protein (Gαs) leads to the opening of downstream hyperpolarization-activated cyclic nucleotide–gated (HCN) channels, resulting in an accelerated heart rate. In contrast, activation of M2 muscarinic receptors (M2Rs) and the inhibitory G protein (Gαi) opens G protein-gated inward rectifier K⁺ (GIRK) channels, slowing the heart rate. In addition to the Gαs and Gαi pathways, there is also the Gαq signaling pathway. In this pathway, activation of Gq-coupled GPCRs can …
Recovering From Dormancy: Fixation Of Csm6-Inducing Spacers In The Bacterial Population, Amanda K. Shilton
Recovering From Dormancy: Fixation Of Csm6-Inducing Spacers In The Bacterial Population, Amanda K. Shilton
Student Theses and Dissertations
Organisms from every kingdom of life constantly need to contend with their parasites to survive and reproduce. Bacteriophages (phages) are the viruses that infect bacteria and often outnumber them in most ecological niches. As a result, prokaryotes have evolved a myriad of defense systems to restrict the propagation of phages as well as other parasitic mobile genetic elements such as plasmids. Genetic loci known as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and their associated cas genes serve as one such defense system in both bacteria and archaea. A hallmark of CRISPR immunity is its adaptive nature in which memories …
A Neuronal Circuit Motif For Leaky Vector Integration, Abby Janke
A Neuronal Circuit Motif For Leaky Vector Integration, Abby Janke
Student Theses and Dissertations
To efficiently navigate their environments, animals ranging from insects to humans can keep track of their trajectory by continuously summing their direction and distance traveled over time. It is not clear how brains perform this fundamental computation––known as path integration––even though neural correlates and computer models abound. In arthropods, spatial-cognition related processes such as path integration are thought to be implemented in the central complex. Experimenters have shown that contiguously arrayed populations of neurons in the Drosophila fan-shaped body, a substructure of the central complex, display sinusoidally shaped bumps of calcium activity that signal vectors relevant for spatial navigation. The …
Replicative Senescence Is Atm-Driven, Reversible, And Delayed By Reduced Atm Activity At Low Oxygen, Alexander James Stuart
Replicative Senescence Is Atm-Driven, Reversible, And Delayed By Reduced Atm Activity At Low Oxygen, Alexander James Stuart
Student Theses and Dissertations
Somatic human cells have a limited proliferative capacity, dividing a certain number of times before entering a predictable proliferative arrest. Telomeres become shorter with every division until a few become 'critically-short' and activate the DNA Damage Response (DDR), thereby inducing this replicative senescence. However, the nature of the activated DDR is unclear. ATM kinase activation at critically short telomeres has been implicated in the induction of senescence, suggesting that the shortest telomeres lack su]icient TRF2 to repress ATM signaling. However, ATM-deficient cells also undergo replicative senescence, raising the question of POT1 deficiency and subsequent ATR signaling. Moreover, low oxygen culture …
Mechanisms And Evolution Of Mitoribosomal Small Subunit Biogenesis, Nathan Harper
Mechanisms And Evolution Of Mitoribosomal Small Subunit Biogenesis, Nathan Harper
Student Theses and Dissertations
The ribosome is the macromolecular machine responsible for all protein synthesis in the cell and is one of the ancient molecular machines involved in the transfer of genetic information to functional molecules. The ribosome is made up of two conserved ribonucleoprotein complexes: the large subunit, responsible for peptide bond synthesis, and the small subunit, responsible for interrogating the match between mRNA codon and tRNA anti-codon. The assembly of the ribosome is a complex process which is tightly controlled to generate functional subunits which exhibit high translational accuracy and processivity. During ribosome biogenesis, ribosomal proteins and a multitude of additional assembly …
Neuromast Optogenetics Reveals Rules Of Spatial Encoding In The Zebrafish Lateral Line, Nicolas Velez-Angel
Neuromast Optogenetics Reveals Rules Of Spatial Encoding In The Zebrafish Lateral Line, Nicolas Velez-Angel
Student Theses and Dissertations
For animals to respond effectively to their environment, their sensory circuits must learn to distinguish between similar patterns of sensory information. A lingering question in neuroscience is how neuronal circuits achieve this performance. In this study, I use the posterior lateral line (pLL) of larval zebrafish to address this question. In the wild, the pLL must differentiate among a variety of hydrodynamic stimuli. However, understanding how fish distinguish between different water-flow stimuli has been challenging due to difficulties in stimulating individual neuromasts. To tackle this, I introduce a novel method in this thesis that combines single-neuromast optogenetics with whole-brain calcium …
Decoding Dynamic Gene Regulation In Hair Cell Development And Regeneration, Caleb C. Reagor
Decoding Dynamic Gene Regulation In Hair Cell Development And Regeneration, Caleb C. Reagor
Student Theses and Dissertations
Identifying the causal interactions between genes and their proteins during the differentiation of specialized cells such as mechanosensory hair cells in vertebrates' inner ears and fishes' lateral lines requires an accurate description of the time-lagged relationships between transcription factors and their target genes. Here I describe Depicting Lagged Causality (DELAY), a convolutional neural network for the inference of gene-regulatory relationships across pseudotime-ordered single-cell trajectories. I first show that combining supervised deep learning with joint probability matrices of pseudotime-lagged trajectories allows the neural network to overcome important limitations of ordinary Granger causality-based methods, for example, the inability to infer cyclic …
Molecular And Metabolic Regulation Of Gastrointestinal Cancer Metastasis, Norihiro Yamaguchi
Molecular And Metabolic Regulation Of Gastrointestinal Cancer Metastasis, Norihiro Yamaguchi
Student Theses and Dissertations
Most of the cancer related mortality caused by metastatic disease rather than primary tumor growth. More than 80% of gastrointestinal cancers initially metastasize to the liver first. While the prognosis of early-stage cancers is improving, a significant proportion of patients have metastatic disease at the time of diagnosis leading to poor survival outcomes. I focused on colorectal cancer and pancreatic cancer, the second and third leading causes of cancer related death in the United States, due to the lack of molecularly targeted therapies available for these cancers. Moreover, understanding the pathophysiological basis of gastrointestinal cancer liver metastasis is of great …
Regulation Of Chromatin Multi-Scale Organization And Function By Linker Histone H1, Irene Duba
Regulation Of Chromatin Multi-Scale Organization And Function By Linker Histone H1, Irene Duba
Student Theses and Dissertations
The three-dimensional organization of the genome is critical for regulating gene expression and maintaining cellular identity. The organizing principles underlying this 3D structure are a subject of much study, and it has proven to be a complex system to unravel. There are multiple scales of genome organization, ranging from single basepair modifications to chromatin compartments spanning many megabasepairs, and innumerable factors influence and regulate genome structure and function. One factor that appears to play a key role is linker histone H1, which is the most prevalent chromatin-binding protein in the cell. It has long been thought to be responsible for …
Seedlings Of Pacific Northwest Plants: A Photographic Guide, Gabriel E. Campbell-Martinez, Roxy Olsson
Seedlings Of Pacific Northwest Plants: A Photographic Guide, Gabriel E. Campbell-Martinez, Roxy Olsson
Rae Selling Berry Seed Bank and Plant Conservation Program
This document presents a visual, non-technical field guide of native and exotic/invasive seedlings that grow wild in the Pacific Northwest. It contains over 550 taxa representing a broad range of families and ecosystems, focusing on species that occur in Oregon and Washington. Species were selected to reflect ecological importance, frequency of occurrence, and relevance to land management, restoration, and conservation. It is intended for a broad audience, including restoration practitioners, land managers, botanists, ecologists, students, naturalists, and others interested in identifying plants at early life stages.
A Scent Of Direction: Exploring Adaptive Olfactory Navigation In Drosophila, Chad Morton
A Scent Of Direction: Exploring Adaptive Olfactory Navigation In Drosophila, Chad Morton
Student Theses and Dissertations
Animals rely on environmental cues, such as odors, to navigate through complex and often dynamic landscapes. While olfactory navigation has traditionally been modeled as a reflexive behavior driven by immediate sensory cues, whether flies can leverage more sophisticated strategies, integrating sensory input with spatial memory and internal representations of their surroundings, remains unclear. A key challenge in studying olfactory navigation lies in the invisible and unpredictable nature of odor plumes, which has made it challenging to accurately assess the ongoing sensory experiences of an animal. To address this challenge, we developed a novel virtual reality (VR) system that head-fixed Drosophila …
Occupational Exposures To Chemicals In Dentistry: A Scoping Review, Geneviève Picard, Tisha Prakash, France Labrèche, Sabrina Gravel
Occupational Exposures To Chemicals In Dentistry: A Scoping Review, Geneviève Picard, Tisha Prakash, France Labrèche, Sabrina Gravel
Revues de littérature, synthèses de connaissances
The dental workforce comprises a variety of professions, most of which are predominantly occupied by women. Dental workers can be exposed to numerous toxic chemicals such as mercury, methacrylate polymers, and silica. This scoping review aims to synthesize the scientific literature on quantified chemical exposures and to identify research gaps in occupational chemical hazards faced by dental professionals. This review followed the Joanna Briggs Institute approach and PRISMA-ScR guidelines, using three concepts to search PubMed, Embase, and Web of Science: workers, dental care, and chemicals. Studies from high-income countries, published in French or English between 2000 and 2024 and reporting …
Identifying The Constituents Of Pyrolysis Oil Using Supercritical Fluid Chromatography- Fraction Collection (Sfc-Fc) And Gas Chromatography- Mass Spectrometry/Vacuum Ultraviolet Spectroscopy (Gc-Ms/Vuv), Sadid Morshed
2025 Fall Honors Capstones Projects - Archive
Plastic waste continues to accumulate as production increases and disposal methods remain insufficient. Even with recycling programs in place, much of the discarded plastic still ends up in landfills or waterways, eventually breaking down into harmful microplastics. One promising solution is the conversion of plastic waste into pyrolysis oil, which can also serve as an alternative feedstock for chemicals. Pyrolysis oil is produced by heating plastics to approximately 800 °C in the absence of oxygen, resulting in a complex mixture of hydrocarbons that includes paraffins, isoparaffins, olefins, naphthenes, and aromatics. Analyzing the amount of oxygen, nitrogen, and sulfur in these …
The Effect Of Zebra Mussels On Minnesota Fish Communities, Benjamin D. Strei
The Effect Of Zebra Mussels On Minnesota Fish Communities, Benjamin D. Strei
Journal of Earth and Life Science
Zebra mussels Dreissena polymorpha are an aquatic invasive species that has been spreading quickly throughout Minnesota water bodies since 1989. Zebra mussels are known to change certain morphological conditions in lakes such as turbidity, phytoplankton abundance, and aquatic invertebrate populations. However, studies showing impacts of the infestation of zebra mussels on the health of a fish community have been hard to prove due to a lack of repeated surveys and a suite of other confounding variables such as natural and seasonal variability, plant community, and lake morphometry. Therefore, the objective of this study is to determine whether zebra mussels have …
Cdh-3/Cadherin, Yap-1/Yap And Egl-44/Tead Promote Syx-2/Syntaxin And Eff-1 Fusogen-Mediated Phagosome Closure, Alec Whited, Aladin Elkhalil, Ginger Clark, Piya Ghose
Cdh-3/Cadherin, Yap-1/Yap And Egl-44/Tead Promote Syx-2/Syntaxin And Eff-1 Fusogen-Mediated Phagosome Closure, Alec Whited, Aladin Elkhalil, Ginger Clark, Piya Ghose
Biology Theses - Archive
Physical interactions between cells, such as cell-cell junctions, can profoundly impact cell fate. A vital cell fate for normal development and homeostasis is programmed cell death. Cells fated to die must be efficiently cleared away via phagocytosis, and defects are associated with a variety of diseased states. Whether cell-cell physical associations affect programmed cell elimination has not been well-explored. Here we describe, in vivo, a cell-cell adhesion-driven signaling pathway that ensures compartment-specific cell clearance during development. We previously described the specialized cell death program “Compartmentalized Cell Elimination” (CCE) in the C. elegans embryo. During CCE, the tail-spike cell (TSC), a …
Resveratrol Exerts Anti-Inflammatory Effects On Human Thp-1 Macrophages, Valeria B. Martinez
Resveratrol Exerts Anti-Inflammatory Effects On Human Thp-1 Macrophages, Valeria B. Martinez
Chemistry & Biochemistry Theses - Archive
Inflammation is a natural biological response to harmful stimuli. It initiates a series of reactions that prompt defensive and curative mechanisms, ridding the body of offending agents and healing remaining injuries. Inflammation involves the intricate communication between cells, requiring complex signaling that mediates various pathways. This acute form of inflammation is vital for our survival, promoting a myriad of mechanisms that function to defend and heal. However, if this inflammatory response is not resolved, it results in a prolonged condition referred to as chronic inflammation. This persistent inflammatory state is incredibly harmful, damaging the host's healthy cells, tissues, and organs. …
Impact Of Glufosinate On Soil Microbial Community Dynamics, Sarobi Das
Impact Of Glufosinate On Soil Microbial Community Dynamics, Sarobi Das
Biology Dissertations - Archive
The increasing global regulations of glyphosate due to its possible carcinogenicity and environmental hazards have necessitated the search for alternative herbicides. Glufosinate-ammonium offers a sustainable attribute due to its low toxicity and limited reported herbicide resistance cases. Despite its increasing agricultural importance, very limited studies are done on its environmental impact, especially on the soil systems. This thesis examines the ecological behavior of glufosinate in soil, precisely focusing on its effect on the dynamics of soil microbiome and the potential use of Bradyrhizobium japonicum USDA110 for bioremediation by reversing the effect of microbial dysbiosis. A series of 30-day mesocosm studies …
How Individual Traits Predict Distribution Patterns And Community Convergence, Zachary K. Lange
How Individual Traits Predict Distribution Patterns And Community Convergence, Zachary K. Lange
Biology Dissertations - Archive
One of the fundamental questions in biology is whether natural conditions lead species and communities toward predictable outcomes. Answering this question requires understanding how traits of individual organisms are connected to species- and community-level patterns. In Chapter 2, I examined how thermal physiology and environmental temperatures interact to determine the distribution patterns of Anolis lizards on the Greater Antilles. I combined lab-measured thermal traits (critical thermal minimum: CTmin, critical thermal maximum: CTmax, thermal preference: Tpref) with occurrence and abundance data from 21 species of Anolis lizards collected from extensive mark-resight surveys of communities across …
A Comparative Study On The Therapeutic Efficacy Of Manual Versus Automated Prepared Platelet Poor Plasma Gel For Atrophic Acne Scar Treatment: A Prospective Randomized Interventional Study, Yassmin Gamal Salem Dorgham, Fatma Faisal El Dakrory, Marwa Zohdy Ali Moubarak
A Comparative Study On The Therapeutic Efficacy Of Manual Versus Automated Prepared Platelet Poor Plasma Gel For Atrophic Acne Scar Treatment: A Prospective Randomized Interventional Study, Yassmin Gamal Salem Dorgham, Fatma Faisal El Dakrory, Marwa Zohdy Ali Moubarak
Mansoura Medical Journal
Introduction Atrophic acne scars are challenging to treat, prompting interest in regenerative therapies like platelet-poor plasma (PPP) gel. The purpose of this study is to compare the therapeutic efficacy and safety of manually versus automatically prepared PPP gel for treating atrophic acne scars. Material and Methods In a prospective, randomized, single-blind study, 40 patients with atrophic acne scars were divided into two equal groups. Group 1 received manually prepared PPP gel, and Group 2 received automated PPP gel, both following subcision. Treatment outcomes were evaluated using dermoscopic imaging, Goodman and Baron qualitative grading system, and patient satisfaction scores over a …
Serum Resistin Levels In Patients With Acne Vulgaris And It's Correlation With Disease Severity, Marwa M. Lasheen, Magdy A. Elsohafy, Gehad M. El Mazny, Manar A. Hassan
Serum Resistin Levels In Patients With Acne Vulgaris And It's Correlation With Disease Severity, Marwa M. Lasheen, Magdy A. Elsohafy, Gehad M. El Mazny, Manar A. Hassan
Mansoura Medical Journal
Background: Acne is a condition characterized by inflammation of the pilosebaceous unit, and resistin—an inflammatory hormone may contribute to its pathogenesis, as studies show altered serum levels in acne patients. This work aimed to evaluate serum resistin levels in acne vulgaris patients and its association with disease severity. Methods: This Case control study involved 46 individuals had acne vulgaris, ranged in age from 18 to 35, free of systemic medication for the three months or topical treatment for the last month and 46 apparently healthy age and sex matched subjects. The patients were then split into two categories: Cases (n …
Interleukin-38 Serum Level In Nonsegmental Vitiligo Patients And Its Correlation With Disease Activity And Disease Severity, Aya Adel, Mohammed El- Kamel, Manar Ali Hassan
Interleukin-38 Serum Level In Nonsegmental Vitiligo Patients And Its Correlation With Disease Activity And Disease Severity, Aya Adel, Mohammed El- Kamel, Manar Ali Hassan
Mansoura Medical Journal
Background Vitiligo is a multifactorial disease in which autoimmunity plays a central role. Interleukin (IL)-38, an innate immune cytokine secreted by keratinocytes and other cells, is believed to have a role in vitiligo progression. Aim To assess the serum levels of IL-38 in cases with non-segmental vitiligo and to examine its correlation to disease severity and disease activity. Methods This case control study included 60 patients with vitiligo and 20 healthy subjects as a control group. According to the disease severity, the cases were allocated into three groups: mild, moderate and severe. Each group included 20 patients. The affected body …
The Association Between Stress-Related Disorders And Chronic Pelvic Pain Syndrome In Males: A Narrative Review, Abdinur Jama Farah, Mohammed Hegazy Abdulhalem, Wafaa Abdel-Hakim El-Bahaey, Ahmed Sobhy El Hefnawy
The Association Between Stress-Related Disorders And Chronic Pelvic Pain Syndrome In Males: A Narrative Review, Abdinur Jama Farah, Mohammed Hegazy Abdulhalem, Wafaa Abdel-Hakim El-Bahaey, Ahmed Sobhy El Hefnawy
Mansoura Medical Journal
Background Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) in males is a multifactorial clinical syndrome with significant impact on quality of life (QoL). Objective To explore the link between psychological stress and chronic pelvic pain in males through reviewing the relevant articles in CPPS literature. Review summary CPPS in males is a complex condition marked by persistent pelvic pain, urinary symptoms, and sexual dysfunction without identifiable infection or pathology. Its unclear etiology and significant impact on quality of life make it a challenging clinical problem. Growing evidence suggests that psychological stress plays a key role in symptom onset and persistence by …
Evaluation Of Serum Ischemia Modified Albumin Level In Male With Androgenic Alopecia, Eman Elnigomy Mahmoud Elnigomy, Fawzia Ameen Saafan, Noha Mohamed Sherif Salah, Mohammed Samir Sultan
Evaluation Of Serum Ischemia Modified Albumin Level In Male With Androgenic Alopecia, Eman Elnigomy Mahmoud Elnigomy, Fawzia Ameen Saafan, Noha Mohamed Sherif Salah, Mohammed Samir Sultan
Mansoura Medical Journal
Introduction Androgenic alopecia (AGA) is the most common type of progressive hair loss in men, influenced by genetic and hormonal factors. Recent studies suggest that oxidative stress may play a role in its pathogenesis. Serum ischemia-modified albumin (IMA), a biomarker of oxidative stress, could provide insights into disease activity and severity in AGA patients. Aim The purpose of this study was to evaluate serum level of ischemia-modified albumin in male patient with androgenetic alopecia in comparison with healthy control. Patients and Methods This case-control study included 45 male patients with androgenetic alopecia and 45 age- and sex-matched healthy controls, recruited …
Interplay Between Amiodarone And Statins: Experimental Evidence Of Synergistic Hepatotoxicity, Hager Zaki Elghareb, Abdel-Motaal M. Fouda, Mohamed Mahmoud Elhadidi, Ahmed Abdel-Monem Elmetwally
Interplay Between Amiodarone And Statins: Experimental Evidence Of Synergistic Hepatotoxicity, Hager Zaki Elghareb, Abdel-Motaal M. Fouda, Mohamed Mahmoud Elhadidi, Ahmed Abdel-Monem Elmetwally
Mansoura Medical Journal
Background: Drug-induced liver injury (DILI) continues to be a main contributor to acute liver failure. So, this study aimed to investigate interactions between amiodarone and atorvastatin concerning hepatic safety, due to increasing clinical practice of their combination for optimal arrhythmia control. Methods: Forty male Sprague Dawley rats were randomly divided into four groups (10 in each group). Group 1 was control group receiving normal saline. Group 2 received Amiodarone-only \ (administered 30 mg/kg/day orally). Group 3 received Atorvastatin only (administered 10 mg/kg/day orally). Group 4 received combination of both amiodarone and atorvastatin in same previous doses. All drugs were dissolved …
Comparison Of The Efficacy Of Topical Cetirizine 1% Versus Topical Minoxidil 5% Solution In Treatment Of Male Androgenetic Alopecia, Hadeer Samy Abd-Elfattah, Bothaina Mahrous Ghanem, Farid Abd-Elreheim Badria, Mohammed Samir Sultan
Comparison Of The Efficacy Of Topical Cetirizine 1% Versus Topical Minoxidil 5% Solution In Treatment Of Male Androgenetic Alopecia, Hadeer Samy Abd-Elfattah, Bothaina Mahrous Ghanem, Farid Abd-Elreheim Badria, Mohammed Samir Sultan
Mansoura Medical Journal
Background: Androgenetic alopecia (AGA) is a common form of non-scaring hair loss characterized by extensive miniaturization of scalp hair follicles. Minoxidil is a standard topical treatment. Cetirizine, an antihistamine with anti-inflammatory properties, may be beneficial by modulating prostaglandins—specifically by inhibiting PGD2 and promoting PGE2, both of which have essential roles in hair cycle regulation. Aim: To compare the efficacy and safety of topical cetirizine 1% versus minoxidil 5% in treating male AGA. Patients and Methods: Forty male patients were randomly allocated in this randomized controlled study to receive topical cetirizine 1% or minoxidil 5%. Clinical photographs and dermoscopic evaluations were …
Vitamin D Status In Coronary Artery Disease, Yasmeen M. Zayed, Hamdy F Marzouk, Alshaimaa H. Abd-Elmaksoud, Ahmed H. Eladawy, Shereen A Mourad
Vitamin D Status In Coronary Artery Disease, Yasmeen M. Zayed, Hamdy F Marzouk, Alshaimaa H. Abd-Elmaksoud, Ahmed H. Eladawy, Shereen A Mourad
Mansoura Medical Journal
Background: Vitamin D deficiency, dyslipidemia, and systemic inflammation are recognized contributors to coronary artery disease (CAD), so the aim of this study was to assess association of serum vitamin D (25(OH)D), traditional and nontraditional lipid indices, and neutrophil lymphocyte ratio (NLR) with CAD risk and severity, and to evaluate their predictive value using the Gensini score. Methods: A cross-sectional study included 55 CAD patients (group I) and 55 age- and sex-matched individuals (group II). lipid profiles, NLR, and serum 25(OH)D levels were measured. Nontraditional lipid indices, including Castelli’s Risk Indices and atherogenic coefficient were calculated. The severity of CAD was …
Low-Carbohydrate, Low-Fat, And Balanced Diets In Weight Reduction Among Obese Adolescents., Ashraf A. Elsharkawy, Gihan Fouad Ahmad, Ahmed El-Husseiny, Amany K. Elhawary, Ola Shawky Ahmed, Asmaa Taha Zaher Taha, Fatma El-Zahraa M. Hashish
Low-Carbohydrate, Low-Fat, And Balanced Diets In Weight Reduction Among Obese Adolescents., Ashraf A. Elsharkawy, Gihan Fouad Ahmad, Ahmed El-Husseiny, Amany K. Elhawary, Ola Shawky Ahmed, Asmaa Taha Zaher Taha, Fatma El-Zahraa M. Hashish
Mansoura Medical Journal
Background: Obesity in adolescents is a major public health concern, leading to early onset of metabolic abnormalities. This study aimed to compare the effects of the Low- Carbohydrate Diet (LCD) and Low-Fat Diet (LFD) in comparison with the balanced calculated diet (BCD) on weight reduction in obese adolescents and their impact on metabolic health markers. Patients and methods: 75 obese adolescents aged less than 18 years were enrolled in this prospective, randomized, controlled study and were randomly assigned to either LCD group, LFD group, or BCD group. Anthropometric and laboratory measures were collected before and after a 10-week intervention. Results: …