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State Of The Fisheries: Status Reports Of The Fisheries And Aquatic Resources Of Western Australia 2024/25, Stephen J. Newman, Ainslie Denham, Lebo Selemela, Jenny Moore

Status Reports of the Fisheries and Aquatic Resources

The Status Reports of the Fisheries and Aquatic Resources of Western Australia (SRFAR) provides an annual update on the state of the fish stocks and other aquatic resources of Western Australia (WA). These reports outline the most recent assessments of the cumulative risk status for each of the aquatic resources (assets) within WA’s six bioregions using an Ecosystem Based Fisheries Management (EBFM) approach. The Department of Primary Industries and Regional Dveelopment’s (DPIRD) risk based EBFM framework is the WA Government’s basis for management of all of WA’s aquatic resources.

Assets examined in each bioregion include the meso-scale ecosystems and aquatic …

Architects Of Mrna Fate: Molecular And Cellular Control Of P-Body Organization In The Drosophilia Melanogaster Female Germline, Samantha Milano

Dissertations, Theses, and Capstone Projects

Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein condensates that regulate mRNA storage, translational repression, and decay. While the biochemical principles governing condensate assembly have been extensively studied in vitro, how P-body organization is established and dynamically regulated in vivo to control specific mRNA populations remains poorly understood. This dissertation investigated the molecular and cellular mechanisms that govern P-body architecture and function in the Drosophila melanogaster female germline. First, I identified the conserved LSm protein Trailer Hitch (Tral) as a central organizer of P-body architecture. Using quantitative confocal and super-resolution microscopy combined with chemical perturbations, I showed that Tral coordinates the …

Guide To The Crawford-Beck Vineyard Collection, Linfield University Archives

Linfield Archives Finding Aids

In 2005, David Beck and Jeanne Crawford purchased Casa-Blanca Vineyard and renamed it as Crawford-Beck Vineyard and owned it for 17 years. This collection focuses on the evolution of Crawford-Beck Vineyards from 2005 to 2023. It contains multiple business documents and records, such as expansion plans, invoices, and LIVE evaluation records. The collection also explores the personal growth and achievements of David and Jeanne Beck, the owners of Craw-Beck Vineyard. This includes their enrollment at Chemeketa Community College, their involvement in the wine industry in Oregon, and their personal assortment of books and articles. The collection also contains material outside …

Organic Pesticides: A General Overview, Marion Murray, Ann Mull

All Current Publications

Organic pesticides are naturally occurring, nonsynthetic, or minimally processed substances that control unwanted organisms in the environment. Categories include insecticides, herbicides, fungicides, and miticides.

Machine Learning-Enabled Chemical Ecology For Integrated Pest Management: From Volatiles To Field Applications, Steve B.S. Baleba, Victor O. Omondi, Pascal Aigbedion-Atalor, Emmanuel Peter, Souleymane Diallo, Komi Mensah Agboka

All Peer-Reviewed Publications

Machine learning is transforming chemical ecology by accelerating the discovery and deployment of semiochemical-based tools for precision pest management. These advances are particularly important in the face of climate change, pesticide resistance, and the growing need for sustainable agricultural intensification. This review synthesizes how machine learning can be applied across the semiochemical discovery and implementation pipeline, from chemical signal detection to field deployment and decision support for integrated pest management. We review major machine learning approaches and demonstrate how they extract biologically relevant information from high-dimensional chemical, electrophysiological, behavioral, sensor, and field datasets. These methods accelerate semiochemical discovery, prioritize candidate …

The Effects Of Chronic Nicotine Exposure On Dopamine-Mediated Reinforcement Learning And Striatal Neurotransmission, Srishti Bose

Dissertations, Theses, and Capstone Projects

Tobacco is one of the most widely used substances across the United States; tobacco consumption is linked with several diseases and is one of the leading causes of preventable death in the country. Nicotine is the active substrate found in tobacco products, acting as a stimulant, which reinforces continued use. The introduction of tobacco-free options such as e-cigarettes and oral pouches has driven an increase in nicotine exposure across the population, especially in young adults. Acute nicotine use induces neuroadaptations in the mesolimbic dopaminergic system, which mediates reinforcement learning and addiction, that potentiates reward-related neurotransmission. Furthermore, there are clinical studies …

The Role Of External Factors In Shaping Carbohydrate Conformational Landscapes, Murat Yaman

Dissertations, Theses, and Capstone Projects

Carbohydrates (glycans) are among the most structurally diverse biomolecules and participate in a wide range of biological processes, including molecular recognition, cell adhesion, immune response, host-pathogen interactions, and cellular signaling. Their biological functions are governed by a complex interplay between sequence, stereochemistry, conformational flexibility, and environmental factors. However, the structural heterogeneity and dynamic nature of glycans present significant challenges for both experimental characterization and theoretical modeling. In particular, the relationships between glycan structure, conformational dynamics, and the resulting potential energy surfaces remain incomplete.

This dissertation investigates how external factors modulate the potential energy surfaces of carbohydrates through a combination of …

Exploring The Backgrounds, Experiences, Motivations, And Development Of School-Based Wheelchair Sport Coaches, Deborah Shapiro, Scott Douglas, Jp Barfield, Laurie A. Malone

Journal of Coach Development

Coaching in adapted sport is a complex and demanding practice that requires both specialized technical expertise and a deep understanding of disability. This study explored the motivations, backgrounds, and developmental pathways of interscholastic school-based wheelchair sport coaches. We examined how coaches are introduced to wheelchair sport coaching, their initial and ongoing development, and their perspectives on effective coaching and training practices. A total of 17 coaches (10 men, 7 women) with 1 to 17 years of experience in wheelchair sports coaching from 7 interscholastic wheelchair sports teams participated in one 60-minute mini focus group discussion and responded to a set …

First Records Of The Rare Nearctic Water Boatman Palmacorixa Janeae (Hemiptera: Corixidae) In The United States, Kurt L. Schmude, Gerald Shepard, Adam Frankiewicz

The Great Lakes Entomologist

We report the first record of the rare water boatman, Palmacorixa janeae Brooks (Hemiptera: Corixidae), from the United States. Two hundred and forty specimens were collected in Wisconsin from Chequamegon Bay in Lake Superior. Palmacorixa gillettei Abbott, a similar species known from the area, was also identified among the samples. Most specimens, all of which were adults, were collected at night using a neuston net towed along the surface for approximately 5 minutes. The adults were found in areas that were 34 meters to 4.2 kilometers from the shore that had depths ranging from 1.0 to 5.5 meters. All representatives …

Paper Wasp Species Polistes Fuscatus (Hymenoptera: Vespidae) Tracks Urban Lead (Pb) Levels More Than Polistes Dominula, Lindsey R. Kemmerling, Anna L. Lovat, Allison A. Hanka, Emilie C. Snell-Rood

The Great Lakes Entomologist

Lead (Pb) is a persistent, toxic pollutant with widespread but inequitably distributed impacts, especially for humans in urban areas. The impacts of lead pollution on other organisms is largely unknown, even as they commonly experience exposure to lead alongside humans. We tested hypotheses regarding the lead concentrations of paper wasps across a gradient of pollution relative to soil and human lead levels, and correlations with wasp body condition. We collected two species of paper wasp across an urban gradient of lead pollution: Polistes fuscatus (Fabricius) (Hymenoptera: Vespidae), native to our study location, and Polistes dominula (Christ), nonnative to our study …

Could The European Thanasimus Formicarius Outcompete The North American Thanasimus Dubius (Coleoptera: Cleridae) If Introduced To North America?, Robert A. Haack, Robert K. Lawrence

The Great Lakes Entomologist

A federal quarantine was enacted in the United States (US) in the fall of 1992 in response to discovery of the Eurasian pine shoot beetle, Tomicus piniperda (L.) (Coleoptera: Scolytinae), in July 1992 in Ohio. The quarantine regulated movement of pine products (e.g., Christmas trees, nursery stock, and logs) at the county level from infested to uninfested US states. A classical biological program was considered for T. piniperda starting in 1995, focusing on the Eurasian clerid beetle Thanasimus formicarius (L.), an important predator of T. piniperda. Concerns were raised in 1996 that if T. formicarius were released in the …

Fecundity Of Thanasimus Dubius (Coleoptera: Cleridae) Rebounds After A Period Of Prey Scarcity, Robert A. Haack, Robert K. Lawrence

The Great Lakes Entomologist

We field-collected Thanasimus dubius (Fabricius) (Coleoptera: Cleridae) adults during spring, maintained them separately in the laboratory, and initially gave them four bark beetle adults [Ips grandicollis (Eichhoff) or Tomicus piniperda (L.) (Coleoptera: Curculionidae: Scolytinae)] daily as prey. Using a subset of the female clerids (N = 41), we assigned them to one of four feeding groups that varied in the number of prey provided daily. For the first four weeks of a 12–week study, the four diets were: four prey daily, two prey daily, one prey daily, and one prey every 2 days. After four weeks, all females were …

Cover Pages For Tgle Vol. 59 Nos. 1 & 2

The Great Lakes Entomologist

Cover Pages for TGLE Vol. 59 Nos. 1 & 2

Volume 9 (2026) Climate And Responsibility

International Journal on Responsibility

This issue focuses on the various ways responsibility affects environmental justice. Specifically, this volume urges us to think about how societal and individual (in)action influences ecological crises and what informs this behavior, with a specific focus on religious and Indigenous beliefs and values.

Erratum: Genetic Variations In Extracellular Matrix Degradation Pathways Linking To Major Depressive Disorder: Evidence From A Large-Scale Genetic Association Study, Halliru Zailani, Daniel Tzu-Li Chen, Sheng-Che Lin, Jia-Hau Lee, Mei-Ling Li, Bing-Fang Huang, Jane Pei-Chen Chang, Kuan-Pin Su

BioMedicine

No abstract provided.

Pneumoperitoneum As A Rare Complication Of Percutaneous Vertebroplasty: A Case Report, Chen-Ting Yang, I-Han Hsiao, Chun-Chung Chen, Der-Yang Cho, Hui-Shan Lu, Po-Fan Chiu

BioMedicine

A 70-year-old woman with a history of hepatocellular carcinoma and bone metastasis underwent percutaneous vertebroplasty for multilevel pathological vertebral compression fractures due to back pain persisting despite conservative treatment. Subsequently, she reported significant pain relief; however, on postoperative day 1, she complained of intermittent, diffuse, and severe abdominal pain. Imaging examination revealed free air in the retroperitoneum and paraspinal space, suggesting hollow organ perforation. She refused exploratory surgery and was consequently discharged against medical advice with only oral antibiotics. Two weeks later, she returned for follow-up. She was in good condition with stable vital signs and no signs of toxic …

Tracking The Course Of Fibrodysplasia Ossificans Progressiva In A Patient With The Classic Acvr1 Mutation, Mohamed Mostafa Kotb, Usama Farghaly Omar, Bishoy Raafat Zaky, Arun-Kumar Kaliya-Perumal

BioMedicine

Fibrodysplasia Ossificans Progressiva (FOP) is an extremely rare and debilitating genetic disease affecting approximately 1 in 2 million people. It is caused by a heterozygous gain-of-function mutation in the gene encoding activin A receptor type I (ACVR1), leading to dysregulated bone morphogenetic protein (BMP) signaling. Clinically, the disease features progressive heterotopic ossification, with bone forming in sites of soft tissue inflammation. We report a 7-year-old boy with two isolated ectopic bone masses in the paraspinal muscles of the neck and lumbar spine, resulting in pain and restricted spinal mobility. Genetic analysis revealed the classic c.617G>A mutation in the gene …

Neuroinflammatory And Neuronal Damage Biomarkers In Depression: A Meta-Analysis Of Hmgb1, S100Β, And Nse Levels, Ikbal Andrian Malau, Suet-Kei Wu, Jane Pei-Chen Chang, Cheng-Ho Chang, Chun-Hung Chang, Ming-Jun Tsai, Yung-Chih Chiang, Kuan-Pin Su

BioMedicine

Background: Depression is associated with neuroinflammation and dysfunction of neurons and glial cells. Immune activation and damage-associated signals such as S100 calcium-binding protein B (S100β) and high mobility group box 1 (HMGB1) amplify inflammation, leading to neuronal injury. Neuron-specific enolase (NSE) reflects such injury. These molecules may serve as potential biomarkers of depression.

Aims: This study compared levels of S100β, HMGB1, and NSE in individuals with depression versus non-depressed controls.

Methods: PubMed, Embase, and Web of Science were searched up to April 5, 2025, using the terms “S100B AND Depression”, “neuron specific enolase AND Depression”, and “HMGB1 …

Design And Development Of Novel Peptidomimetic Compounds For Cancer Therapeutics: Focus On Hsp90–Cdc37 Interaction, Sarath Perumal, Ramanathan Karuppasamy

BioMedicine

Background: The HSP90 and CDC37 molecular chaperone complex governs the

stability and function of numerous client protein kinases, making it a crucial cancer target. Given their central role, disrupting this interaction induces proteotoxic stress and inhibits tumor progression. Therapeutic peptides are the mainstay of treatment for disruption of key interactions, yet they face limitations such as toxicity, resistance, and poor stability. Aim: This study aims to leverage peptidomimetics as novel disruptors of the HSP90–CDC37 interaction. Methods: Two peptides, a 9-mer and a 7-mer, were rationally designed by analyzing key regions facilitating HSP90–CDC37 complex formation. In silico mutational analysis identified …

Evaluation Of The Anti-Inflammatory Properties In Vitro, In Vivo And In Silico, Of The Snail Slime Helix Aspersa Müller, Marouane Aouji, Malak Zirari, Mariame Taibi, Meryem Lamdak, Amine Rkhaila, Rachid Bengueddour

BioMedicine

Background: The search for effective natural alternatives to synthetic non-steroidal antiinflammatory drugs (NSAIDs), which are often associated with undesirable side effects, is an important axis of current research. The slime of the snail Helix aspersa Müller, is a traditional remedy that deserves scientific investigation for its potential therapeutic properties.

Purpose: This study aimed to comprehensively evaluate the anti-inflammatory effects of Helix aspersa Müller slime using a combination of in vitro, in vivo, and in silico methodologies.

Methods: In vitro analyses included assays for inhibition of protein denaturation, antiprotease and antilipoxygenase activities, and membrane stabilization, with diclofenac and indomethacin as reference …

Traditional Chinese Medicine And Healthcare Utilization In Bipolar Disorder: A Population-Based Study With Propensity-Matched And Mirror-Image Analyses, Shu-Ping Chen, Su-Tso Yang, Kai-Chieh Hu, Hui-Chih Chang, Jane Pei-Chen Chang, Kuan-Pin Su

BioMedicine

Background: Bipolar disorder (BD) is a chronic relapsing illness associated with high rates of acute psychiatric hospitalizations (APH) and emergency services (ES) use, placing burdens on healthcare systems. Many patients seek complementary modalities, including traditional Chinese medicine (TCM), alongside standard pharmacotherapy. However, population-based evidence regarding TCM’s effect on acute healthcare utilization in BD is lacking.

Methods: Using data from Taiwan’s Longitudinal Health Insurance Database 2000 (LHID 2000), this population-based study employed propensity score matching (PSM) based on age, gender, the index year (defined as the calendar year of the index date for TCM users and their matched nonTCM counterparts), and …

Topical Peony And Licorice Decoction Attenuates Exercise-Induced Muscle Pain: A Randomized Double-Blind Self-Controlled Trial In Taiwan, Daniel Tzu-Li Chen, Chang-Wei Hsieh, Chia-Han Tsai, Tzung-Yan Lee, Pin-Chun Chen, Pu-Wei Hou, Kuan-Pin Su, Hen-Hong Chang

BioMedicine

Background

Delayed onset muscle soreness (DOMS) is a common phenomenon that occurs after exercise training, resulting in pain and reduced muscle performance. Previous basic and animal studies have reported that oral use of Peony and Licorice Decoction (PLD), a traditional Chinese formula with anti-inflammatory and muscle-relaxing properties, may be safe and effective for DOMS. However, there have been no clinical studies, particularly on the topical use of PLD, in this field to date.

Material and Methods

Our study is a double-blind, randomized, placebo-controlled trial. We recruited healthy male athletes to assess the effect of external PLD, whose bioactive compounds were …

A Causal Association Between Alkaline Phosphatase And Natural-Cause Mortality: A Mendelian Randomization Study In East Asians And Europeans., Hung-Lin Chen, Ping-Hsun Wu, Yi-Ting Lin, Amrita Chattopadhyay, Hsiu-Yin Chiang, Yu-Ting Lin, Ya-Chi Lin, Che-Chen Lin, Min-Yu Chiang, Hung-Chieh Yeh, I-Wen Ting, Yu-Cyuan Hong, David Ray Chang, Jenq-Wen Huang, Yu-Ting Lin, Wei-Chi Syu, Tzu-Pin Lu, Yi-Chun Tsai, Fuu-Jen Tsai, Chin-Chi Kuo

BioMedicine

Background: Although observational studies show a positive association between alkaline phosphatase (ALP) levels and mortality, a causal study is not yet available.

Objective: We conducted a retrospective cohort study and a systematic one-sample Mendelian randomization (MR) study to investigate the causality of ALP on natural-cause mortality.

Methods: The study used a hospital-based cohort of Asian patients recruited from the China Medical University Hospital (CMUH) and a community-based cohort of white European participants from the UK Biobank (UKB). Two retrospective cohorts included 43,994 patients from CMUH and 80,941 participants from UKB, all aged 50–55 years, with ALP measurements. For the MR …

Data Curation And Integration For Cancer Cell Line Pharmacogenomics Analysis, Meric Kinali

Graduate Masters Theses

Cancer cell lines are essential resources for connecting genomic and molecular features with drug response and identifying biomarkers. Therefore, large-scale cancer cell line resources have been growing, but this introduces challenges such as data standardization, consistent annotation, matching identifiers, cross-database integration, and a reproducible computational framework. CellMiner Cross Database (CellMinerCDB) integrates pharmacogenomic datasets from multiple resources and provides a standardized analysis of cell lines across datasets. This thesis examines cancer cell line cross-databases and their importance in pharmacogenomics, with a particular focus on CellMinerCDB. As part of this work, I developed an R package for the gCSI (Genentech Cell Line …

Effect Of Partial Ablation Of Skeletal Dynamin Related Protein 1 On Mitochondrial Health, Inflammation, And Fibrosis In A Mouse Model Of Duchenne Muscular Dystrophy, Tessa L. Duzz

Graduate Masters Theses

Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder characterized by muscle weakness, degeneration, fibrosis, and impaired muscle regeneration. Mitochondrial dysfunction is an early pathological feature of DMD and has been linked to excessive mitochondrial fission. Dynamin-related protein 1 (Drp1) is a central regulator of mitochondrial fission, a key process in regulating mitochondrial quality and function. Inhibition of Drp1-mediated mitochondrial fission has shown promise as a potential therapeutic target for alleviating pathology and dysfunction in dystrophic muscle. The objective of this study was to determine whether partial skeletal muscle-specific ablation of Drp1 could improve muscle pathology and mitochondrial health in …

Spider Biodiversity And Insecticide Sensitivity Across Active And Restored Cranberry Bogs On Nantucket, Tyler J. Kulak

Graduate Masters Theses

Spiders are one of the most diverse groups of organisms on the planet with over 53,000 species described as of 2026. They provide a suite of ecosystem services including their regulation of problematic pests in agricultural systems, appearing in high biomasses across a breadth of ecological niches. While beneficial as pest regulators, they are also susceptible to the same management techniques as pest organisms and are especially vulnerable to chemical control. Cranberry production in Massachusetts likely benefits from spider ecosystem services, but diversity research on spiders in these systems is limited. This study compares the diversity of spider populations from …

Genomic Based Environmental Health Assessment: Vieques, Puerto Rico, Valeria Hernandez Talavera

Graduate Doctoral Dissertations

From 1941 to 2003, the United States Navy and North Atlantic Treaty Organization (NATO) used Vieques, Puerto Rico, for military training, which led to long-term pollution from metals, organic chemicals, explosives, and per- and polyfluoroalkyl substances (PFAS). While earlier research found these contaminants in the environment and in living organisms, their combined effects on local ecosystems remain poorly understood.

This dissertation used a Genomic-Based Environmental Health Assessment (GEHA) framework to study the ecological risks from past military pollution in Vieques. The approach combined sediment toxicity tests, chemical analysis, gene expression studies, microbial community analysis, and community-based research. The four main …

Innovating A Crustacean Embryo Toxicity (Cet) Assay For Screening Environmental Contaminants, Irina A. Polunina-Proulx

Graduate Doctoral Dissertations

Environmental pollutants can disrupt normal developmental processes, leading to neurobehavioral and developmental abnormalities. Toxicity tests are important for evaluating environmental contaminants; however, standard assays are often time- and cost-intensive and typically require large numbers of vertebrate animals. These limitations highlight the need to reduce reliance on vertebrate testing and to develop New Approach Methodologies that provide comparable results while improving efficiency and cost-effectiveness. This research utilizes a novel screening assay to evaluate developmental toxicity using Hyalella azteca. H. azteca is a freshwater amphipod widely used as a model organism for sediment toxicity in ecotoxicology, yet its embryos have been minimally …

The Correlation Between Medication Adherence, Blood Glucose Levels, And Quality Of Life In Patients With Type 2 Diabetes Mellitus At Ciamis Regional Hospital, Amyla Putri Nurul Nazmi, Nur Rahayuningsih, Lusi N

Pharmacology and Clinical Pharmacy Research

Type 2 diabetes mellitus is a chronic condition requiring continuous treatment, including patient adherence to prescribed medication. This study aimed to explore the relationship between medication adherence, blood glucose levels, and quality of life in patients with type 2 diabetes mellitus at Ciamis Regional Hospital, conducted from January to March 2025, the research employed a quantitative, prospective cross-sectional design involving 49 hospitalized patients. Data included blood glucose levels (RPG, FPG, 2hPG), medication adherence measured using the Medication Adherence Report Scale (MARS-5), and quality of life assessed via the Diabetes Quality of Life-Brief Clinical Inventory (DQOL-BCI). The chi-square test was used …

The Phytochemical Content And Antibacterial Activity Of Purified Extract Of Mangifera Indica L. Against Gram Positive Pathogen, Dewi Andini Kunti Mulangsri, Masduki Faqih, Sugar Arifin, Mutiara Trie Sieya Agustin

Pharmacology and Clinical Pharmacy Research

The purified extract of arum manis mango leaves contained flavonoid compounds by TLC methods and antibacterial activity against Gram-positive and negative pathogens. This research aimed to identify and determine the phytochemical content (mangiferin and flavonoids content) and antibacterial activity against other Gram-positive pathogens. Purification of ethanol extract of arum manis mango leaves by liquid-liquid fraction method. Determination of total flavonoid content and identification of mangiferin used respectively by aluminum chloride and Thin Layer Chromatography method. The disk diffusion method was used to assay antibacterial activity against S. epidermidis, and B. subtilis bacteria with the concentration of the sample such …