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Total Syntheses Of (+)-Geldanamycin, (-)-Ragaglitazar, And (+)-Kurasoin A And Phase-Transfer-Catalyzed Asymmetric Alkylation, Erik J. Hicken

Theses and Dissertations

Geldanamycin possesses various biological activities as seen in the NCI 60 cell line panel (13 nM avg., 70 nM SKBr-3 cells). The predominant mode of action providing these unique results arises from the ability of geldanamycin (GA) to bind to the chaperone heat shock protein 90 (Hsp90). Despite its complicated functionality, the first total synthesis of GA was accomplished, which included two new reactions developed specifically to address the stereochemical features. The final step in the synthesis of GA was a demethylation-oxidation sequence to generate the desired para-quinone. This step could only be accomplished with HNO3/AcOH, producing GA in …

Student Employee Recruitment And Retention Through Campus Partnerships, Corinne M. Daprano, Megan L. Coyle, Peter J. Titlebaum

Health and Sport Science Faculty Publications

Recruitment and retention of student employees are important considerations for any recreational sports department, large or small, because student employees impact both the quantity and quality of programs and services. This article proposes a strategy for establishing partnerships with academic departments to aid in the recruitment and retention of student employees. These partnerships benefit students, the recreational sports department, academic departments, and university student retention efforts. Following a description of this strategy is an example of a partnership that has been successfully established at one Midwestern university.

2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr, Steve Slane was the guest speaker.

When Should Judges Admit Or Compel Genetic Tests?, Diane E. Hoffmann, Karen H. Rothenberg

Faculty Scholarship

No abstract provided.

Santa Clara Magazine, Volume 47 Number 2, Fall 2005, Santa Clara University

Santa Clara Magazine

6 - THE DRIVE TO CREATE by Elizabeth Kelley Gillogly '93. Albert Hoagland, an adjunct professor at SCU for more than 20 years, helped to build the first disk drive. Now is he working to preserve the history of magnetic disk storage.

10 - UNFINISHED MESSAGE by Toshio Mori. We share an excerpt from a collection of short stories by Mori, whose work highlights the plight of Japanese immigrants in the U.S. during World War II. The book is a part of the California Legacy Series, a partnership between SCU and Heyday Books.

14 - THE FAMILIAR STRANGER By Cynthia …

The Theory Of Planned Behavior: Predicting Physical Activity And Cardiorespiratory Fitness In African American Children, Jeffrey J. Martin, Pamela Hodges Kulinna, Nate Mccaughtry, Donetta Cothran, Joe Dake, Gail Frances Fahoome

Kinesiology, Health and Sport Studies

The purpose of our study was to evaluate the ability of the Theory of Planned Behavior (TPB) to predict African American children’s moderate to vigorous physical activity (MVPA) and cardiorespiratory fitness. Children (N = 548, ages 9–12) completed questionnaires assessing the TPB constructs and MVPA and then had their cardiorespiratory fitness assessed with the Progressive Aerobic Cardiovascular Endurance Run (PACER) test. Commonly used Structural Equation Modeling fit indices suggested the model was an adequate representation for the relationships within the data. However, results also suggested an extended model which was examined and supported. Tests of direct paths from subjective …

Relationships Of Intercropped Maize, Stem Borer Damage To Maize Yield And Land-Use Efficiency In The Humid Forest Of Cameroon, A. Chabi-Olaye, C. Nolte, F. Schulthess, C. Borgemeister

All Peer-Reviewed Publications

Stem borers are the most important maize pests in the humid forest zone of Cameroon. Field trials were conducted in the long and short rainy seasons of 2002 and 2003 to assess the level of damage and yield reductions caused by stem borers in monocropped maize and in maize intercropped with non-host plants such as cassava, cowpea and soybean. The intercrops were planted in two spatial arrangements, i.e. alternating hills or alternating rows. All intercrops and the maize monocrop were grown with and without insecticide treatment for assessment of maize yield loss due to borer attacks. The land-use efficiency of …

Orientation To Nutrition Care Process Standards Improves Nutrition Care Documentation By Nutrition Practitioners, Nancy Hakel-Smith, Nancy M. Lewis, Kent M. Eskridge

Department of Nutrition and Health Sciences: Faculty Publications

Objective — To compare documentation of two groups of clinical nutrition practitioners for evidence of the nutrition care process.

Design — This study used a comparative descriptive design. A retrospective chart review was conducted on all nutrition documentation in closed patient records. Documentation of two groups of nutrition practitioners (institution A = practitioners who received initial orientation and routine reinforcement in use of nutrition care process standards; institution B = practitioners who received orientation in use of a further assessment and medical nutrition therapy intervention procedure) was compared for evidence of a six-step nutrition care process.

Sample/Setting — The sample …

Feature-Specific Penalized Latent Class Analysis For Genomic Data, E. Andres Houseman, Brent A. Coull, Rebecca A. Betensky

Harvard University Biostatistics Working Paper Series

No abstract provided.

Online Dictionary Of Invertebrate Zoology: B, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

baccate bacillary bacilliform back-cross back-mutation bacteremia bacteriophagous baculiform baculite baenomere baenopoda baenosome Baer's bailer balanced balancers balanoid balantin balantine Balbiani Balbiani's bald Baldwin ballonets ballooning band barb barbate, barbatus barbula bark baroceptor, baroreceptor barotropism barrier basad basal basalar basalia basalis base basement bases basicarnal basicerite basiconic basicosta basicostal basicoxite basifemoral basifemur basilaire basilar basilateral basilemma basimandibula basimaxilla basimetrical basinym basioccludent basiophthalmite basiperiphallus basipharynx basipod basipodite basiproboscis basipulvilli basirostral basis basiscopic basiscutal basisternum basistylus basitarsal basitarsus basitergal basitibial basitrich basitrichous basivalvula basket basopinacocytes batatiform Batesian bathmis bathyal bathylimnetic bathymetric bathypelagic battery batumen bave B-chromosome, bdelloid bead beaded beak beaked bean beard …

An Artificial Neural Network That Utilizes Hip Joint Actuations To Control Bifurcations And Chaos In A Passive Dynamic Bipedal Walking Model, Max J. Kurz, Nikolaos Stergiou

Journal Articles

Chaos is a central feature of human locomotion and has been suggested to be a window to the control mechanisms of locomotion. In this investigation, we explored how the principles of chaos can be used to control locomotion with a passive dynamic bipedal walking model that has a chaotic gait pattern. Our control scheme was based on the scientific evidence that slight perturbations to the unstable manifolds of points in a chaotic system will promote the transition to new stable behaviors embedded in the rich chaotic attractor. Here we demonstrate that hip joint actuations during the swing phase can provide …

Isokinetic Knee Strength In Females With Fibromyalgia, Flora F. Shafiee

Loma Linda University Electronic Theses, Dissertations & Projects

Objectives: To compare knee flexors and extensors muscle strength, total work, and power between females with fibromyalgia (FM) and matched healthy controls.

Methods: This is the first study to measure knee muscle power and total work in females with FM. Thirty-one females with FM and thirty-one healthy females completed isokinetic testing of knee flexors and extensors of their dominant leg using a Cybex Norm Isokinetic Dynamometer. Two knee muscle groups (flexors and extensors) at two angular velocities (607sec and 1807sec) were tested for both groups. Both muscle groups were assessed continuously using five reciprocal concentric-concentric cycles, followed by five eccentric-eccentric …

Validation Of A Serotonin Depletion Checklist In Parkinson’S Disease, Kelly Diane Darby Holder

Loma Linda University Electronic Theses, Dissertations & Projects

The distinctive pathological marker of Parkinson’s Disease (PD) is the progressive death of neurons that produce dopamine; however, there are also major alterations in the production of quantities of other neurotransmitters, such as norepinephrine and serotonin that contribute to the signs, symptoms, neuropsychological manifestations of the diseases. PD patients can be divided into classes based on the manifestation of motor symptoms, type A, classified as tremor dominant, and type B PD, classified as akinetic. Type B PD patients, often manifest symptoms in which serotonin deficiency plays an important role, such as frontal cognitive impairments, which often includes a history of …

Effects Of Resistance Training Volume And Variety On Dietary Intake And Mood State In Untrained Subject, Suzette K. Smith

Loma Linda University Electronic Theses, Dissertations & Projects

Background: While there is research on the effects of aerobic training on various aspects of mood state and nutrient intake, little is known of the effect of resistance training on these variables.

Purpose: To examine the effects of resistance training (RT) volume and variety on total energy (kcal) and macronutrient intake, and mood states in a healthy, untrained population.

Method:The investigation was part of a prospective experimental study examining the effects of three RT protocols on body composition and strength. An initial 102, healthy, untrained male and female participants, ages 20-40, were recruited, and randomized into one of three …

An Electromyographic Assessment Of Lumbar Paraspinal Muscles During Core Stability Exercises, Alicia Marleina Osuna

All-Inclusive List of Electronic Theses and Dissertations

Objective: Clinicians often use Swiss balls in exercise regimens to recruit activity of the paraspinal musculature. However, we do not know if muscle activity differences exist while performing an exercise on a stable or unstable surface. Design and Settings: A 1 X 2 factorial with repeated measures design guided this study. The single within-subjects factor was a core stability exercise with 2 levels: a stable condition (chair) and an unstable condition (Thera-band® exercise ball). The dependent variables were the integrated electromyography (I-EMG) amplitude of the left and right lumbar paraspinal musculature. Subjects: Sixteen moderately active and healthy male subjects (age: …

The Effects Of An Analgesic (Biofreeze®) On The Motoneuron Pool Excitability Of The Soleus Muscle, Desiree R. Barth

All-Inclusive List of Electronic Theses and Dissertations

Objective: The purpose of this study was to determine the effects on the Hoffman reflex and motor response with an analgesic (Biofreeze®). Design: The study was a 2X6 design. The independent variables in this study were treatment and time. The dependent variables were the H-reflex (volts) and the M response (volts). Treatment was randomly assigned to control for the effects of order. Setting: This study took place in the Exercise Physiology Laboratory located in the Health and Human Performance Building at Indiana State University. Subjects: 14 volunteers who were physically active and had no known neurological problems. Measurements: Skin and …

Extraocular Muscle Activity, Rapid Eye Movements And The Development Of Active And Quiet Sleep, Adele M. H. Seelke, Andrew J. Gall, Karl Æ. Karlsson, Mark S. Blumberg

Faculty Publications

Rapid eye movements (REMs), traditionally measured using the electrooculogram (EOG), help to characterize active sleep in adults. In early infancy, however, they are not clearly expressed. Here we measured extraocular muscle activity in infant rats at 3 days of age (P3), P8 and P14-15 in order to assess the ontogeny of REMs and their relationship with other forms of sleep-related phasic activity. We found that the causal relationship between extraocular muscle twitches and REMs strengthened during the first two postnatal weeks, reflecting increased control of the extraocular muscles over eye movements. As early as P3, however, phasic bursts of extraocular …

Donepezil Effects On Mood In Patients With Schizophrenia And Schizoaffective Disorder, S Craig Risch, Michael D. Horner, Susan R. Mcgurk, Simmy Palecko, John S. Markowitz, Ziad Nahas, C. Lindsay Devane

Dartmouth Scholarship

Donepezil, 5 mg/d for 6 wk then 10 mg/d for 6 wk, and placebo daily for 12 wk in a double-blind cross-over paradigm, was added to the therapeutic regimen of 13 patients with schizophrenia or schizoaffective disorders, clinically stable on atypical antipsychotic medications. Patients had varying degrees of depressive symptoms, ranging from no depression to clinically significant depression. There was no worsening or induction of depression in individual patients or the group as a whole. In addition there was a statistically significant antidepressant effect in the group as a whole during the donepezil condition and a clinically significant antidepressant effect …

Peer-To-Peer Discovery Of Semantic Associations, Matthew Perry, Maciej Janik, Cartic Ramakrishnan, Conrad Ibanez, I. Budak Arpinar, Amit P. Sheth

Kno.e.sis Publications

The Semantic Web vision promises an extension of the current Web in which all data is annotated with machine understandable metadata. The relationship-centric nature of this data has led to the definition of Semantic Associations, which are complex relationships between resources. Semantic Associations attempt to answer queries of the form “how are resource A and resource B related?” Knowing how two entities are related is a crucial question in knowledge discovery applications. Much the same way humans collaborate and interact to form new knowledge, discovery of Semantic Associations across repositories on a peer-to-peer network can allow peers to share their …

Time Efficiency In Computer Assisted Direct Observation Of Physical Activity Using Sofit, Trisha Anderson

Theses and Dissertations

Having valid and reliable methods for assessing physical activity levels is critical to understanding physical activity patterns. Direct observation is a widely used technique for obtaining contextually rich data on physical activity levels in physical education classes. One major limitation of direct observation is that it is time intensive. The use of digital video editing software programs may lessen the amount of time needed to gather the data. The purpose of this study was to compare the amount of time needed to obtain SOFIT (System for Observing Fitness Instruction Time) physical activity data using the traditional paper and pencil method …

Differential Stress Responses In Fish From Areas Of High- And Low-Predation Pressure, Culum Brown, Carolyn Gardner, Victoria Braithwaite

Aquaculture Collection

We subjected fish from regions of high and low levels of predation pressure in four independent streams to a mild stressor and recorded their opercular beat rates. Fish from low-predation areas showed higher maximum, minimum and mean opercular beat frequencies than fish from high-predation regions. The change in opercular beat frequency (scope) was also significantly greater in fish from low- than in fish from high-predation regions. Under normal activity levels, however, low predation fish showed a reduced opercular beat frequency, which may be indicative of reduced activity levels or metabolic rate. Opercular beat frequency was negatively correlated with standard length …

Santa Clara Magazine, Volume 47 Number 1, Summer 2005, Santa Clara University

Santa Clara Magazine

9 - A MOGUL IN THE MAKING By Larry Sokoloff J.D. '92 While working toward his business degree, SCU sophomore Tyler Dickman runs a multimillion-dollar business based in Florida.

10 - TOP OF THE CLASS: FOUNDATION HONORS INNOVATIVE SCU PROFESSORS By Kim Kooyers. This year's winners of the Louis and Dorina Brutocao Award for Teaching Excellence and the Brutocao Family Foundation Award for Curriculum Innovation are examples of the SCU's outstanding teaching scholars.

14 - A GLOBAL ETHIC: A CONVERSATION WITH HANS KUNG By Rita Beamish '74 Hans Kung, scholar, Roman Catholic priest, and author of some 50 books on …

The National Weight Control Registry: Is It Useful In Helping Deal With Our Obesity Epidemic?, James O. Hill, Holly Wyatt, Suzanne Phelan, Rena Wing

Kinesiology and Public Health

The National Weight Control Registry (NWCR) consists of over 4800 individuals who have been successful in long-term weight loss maintenance. The purpose of establishing the NWCR was to identify the common characteristics of those who succeed in long-term weight loss maintenance. We found very little similarity in how these individuals lost weight but some common behaviors in how they are keeping their weight off. To maintain their weight loss NWCR participants report eating a relatively low-fat diet, eating breakfast almost every day, weighing themselves regularly, and engaging in high levels (about 1 hour/day) of physical activity. Because this is not …

A Social Cognitive Perspective Of Physical-Activity-Related Behavior In Physical Education, Jeffrey J. Martin, Pamela Hodges Kulinna

Kinesiology, Health and Sport Studies

The purpose of the current study was to examine student and teacher physical-activity-related behavior using the theory of planned behavior and self-efficacy theory. Although teachers reported an overwhelmingly positive attitude toward teaching physical activity lessons to promote fitness development, they only devoted 4% of their class time to actually demonstrating and promoting fitness. Students were quite sedentary during class spending 61% of class time sitting, standing, or lying down. Using hierarchical regression analyses, teachers' attitudes toward teaching physically active physical education classes accounted for 50% of the variance in teachers' intention. Teachers who demonstrated/promoted fitness and who limited their general …

Evidence-Based Research In Complementary And Alternative Medicine I: History, Francesco Chiappelli, Paolo Prolo, Olivia S. Cajulis

Senior Honors Projects

Contemporary Western medicine has witnessed a fragmentation of our conceptualization of the medical endeavor into ‘traditional medicine’ and ‘non-traditional medicine’. The former is meant to refer to the Western medical tradition, the latter encompasses both ‘complementary’ and ‘alternative’ medical practices. Complementary medicine complements conventional medical treatments, and alternative modes of medical interventions are meant to replace traditional Western medicine. Evidence-based research must be directed at establishing the best available evidence in complementary and alternative medicine. This paper is the first of a set of four ‘lectures’ that reviews the process of evidence-based research, and discusses its implications and applications for …

Nebline, July 2005

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Avoid Portion Distortion With MyPyramid’s Specific Guidelines
Mandevilla — Tropical Vine with Showy Flowers
Fragrance in the Garden
Garden Guide: Things to do this month
Most Leaf Galls Don’t Harm Trees
Traveling This Summer? Find Bedbugs in Hotel Rooms Before They Find You!
Household Hazardous Waste Collections, June 24 & 25
Some Insects Thrive on Rat Poison
P3 Intern Working at Extension
Pine Wilt Disease
How to Sample for Pinewood Nematode
Pine Species to Avoid Planting
Presentation on Sustainable Agriculture, July 8
Predicting the Last Irrigation for Corn, Milo and Soybeans
Irrigating Summer Turf
In Hot Weather, Raise Mower Height …

Theta Activity During Navigation In Virtual Environments, Colleen Margaret Moore

Psychology Theses & Dissertations

Human navigation has gone through many different stages, from guidance by stars to guidance by technology. Theories for performance differences range from differences between individuals, to experience with the environment. Researchers turn to virtual environments during experimentation which are easy to manipulate and easier to measure during navigation. However, fidelity is an issue with regard to transfer of learning to a real world environment. We examined differences in theta activity during navigation in low and high fidelity virtual environments. The researchers recruited thirty-two students between the ages of 18-40 from the university subject pool for voluntary participation. We measured EEG …

Lower Extremity Motion Analysis Patterns During Various Foot-Landing Styles, Nelson Cortes

Human Movement Studies & Special Education Theses & Dissertations

Walking, running, and jumping are considered essential human movement activities that occur on a daily basis. In every landing task, the lower extremity needs to dissipate and absorb the energy that is created by the landing height. In addition, more dissipation is normally needed when landing from higher jumps, which increases the work that needs to be done by joints, muscles, and bones in order to prevent injury. Great amounts of load during a landing have the potential to induce injuries, particularly in the ankle and knee complex. In many sports, such as soccer, basketball, football, and volleyball, there is …

Wright State University College Of Education And Human Services Annual Report, July 1, 2004-June 30, 2005, College Of Education And Human Services, Wright State University

College of Education and Human Services Annual Reports

This Wright State University College of Education and Human Services annual report is from July 1, 2004 through June 30, 2005.

Smokejumper Obituary: Mckeen, E. Clifford (Cave Junction 1958), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.