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Disruption Of Energy Homeostasis By Chemical Mixtures Containing Persistent Pollutants In Hepg2 And C2c12 Cells, Morgan Jacobellis

All Theses

The Environmental Influences on Child Health Outcomes Fetal Growth Studies (ECHO-FGS) birth cohort data was used to identify chemical mixtures associated with adverse outcomes. This biomonitoring study associated specific chemical mixtures in maternal serum with low birth weight or childhood obesity (Pearce et al., 2021). Mixture Profiles 1, 3, and 4, comprised of different observed concentrations of DDE, PCB153, BDE47, and PFOS were prioritized. Mixtures were tested to determine whether they perturbed mitochondrial metabolism and energy sensing pathways. The purpose of this study was to elucidate a potential mechanism linking maternal exposure to mixtures containing persistent organic pollutants (POPs) to …

Field Pea (Pisum Sativum L.) Response To Planting Date In South Carolina Organic Cropping Systems, Tristan Lawrence

All Theses

Field peas (Pisum sativum L.) are not widely cultivated in South Carolina, resulting in limited agronomic data to support farmers interested in this crop. However, field peas hold significant promise as a cool season crop for both organic and conventional growers in the region. Most commercially available field pea cultivars are evaluated and bred for the Pacific Northwest, where environmental conditions differ substantially from those in the southeastern United States. Consequently, there is a lack of region-specific recommendations for successful cultivation in South Carolina. To address this gap, a two-year planting date study was conducted during the …

Dissecting The Complex Genomic Landscape Underlying Oxidative Stress Resistance Using Natural Variation In Yeast, Sonali Lakshika Anne Lenaduwe

Graduate Theses and Dissertations

Stress is experienced across the tree of life. Survival in fluctuating environments depends on a robust genetic architecture. This dissertation examines the genetic and metabolic determinants underlying one such adaptive response: cross-protection. Leveraging natural variation in the stress responses of budding yeast, Saccharomyces cerevisiae, I examine the genetic variation contributing to ethanol-induced cross-protection against oxidative stress. Acquired stress resistance, in which mild pre-exposure improves survival to subsequent stresses, is prevalent across diverse organisms and can involve both same-stress and cross-protection. Using high-throughput bulk segregant analysis (BSA-seq) and advanced intercross mapping populations derived from natural yeast isolates, I identify quantitative trait …

Herbivory Of Phragmites Australis Along A Salinity Gradient In Connecticut Wetlands, Sydney H. Kolz

Honors Scholar Theses

Invasive Phragmites australis (common reed) is widely distributed in New England wetlands, where it often outcompetes native plants and decreases biodiversity throughout the food web. Controlling its invasion is a priority, especially in salt marsh habitat, but current management techniques are inefficient. Leveraging natural processes may improve control strategies, but in order to do so, we must first better understand how abiotic and biotic stressors interact and affect Phragmites. This study focuses on herbivory and salinity, two factors limiting Phragmites’ fitness. I measured soil salinity and quantified the damage of three herbivore guilds (i.e. gall-formers and stem-borers, leaf-chewers, and …

Creatures Of Habit? Impact Of Chick Feeder Tray Location On Feed Consumption At 0-7 Days Of Age, Emily Kate Green

Graduate Theses and Dissertations

Early chick nutrition is critical for establishing target growth performance characteristics in broiler chickens. This study evaluated factors within commercial broiler houses that potentially influence feed consumption during the first 7 days. Three trials were conducted in a 12.2 x 122 m commercial broiler house to assess the effects of house sectioning, spatial barriers, and feedline location. In Trial 1, a one-way experimental design was used in which the house was divided into four equal sections using migration fencing every 30.5 m. House sections served as a fixed factor. Feed was provided using chick trays placed beneath the feed line …

Unveiling Factors Influencing Extract Yield From Milled Rice In Brewing, Matthew Aitkens

Graduate Theses and Dissertations

Rice (Oryza sativa L.) presents a locally sourced, climate-resistant starch source for the brewing industry. As barley faces increased uncertainty due to rising temperatures, Arkansas-grown rice offers a more stable and cost-effective alternative starch source. However, the use of milled adjunct rice by brewers has remained limited, largely due to knowledge gaps about cultivar-specific properties relative to brewing. Chapter 1 provides an overview of rice as a brewing adjunct, reviewing the physiochemical properties important to brewing success. These properties include kernel size, kernel breakage, amylose content, and gelatinization temperature. Mashing strategies for multiple different brewing layouts are overviewed, showing practical …

Assessment Of The Quality, Practicality, And Economic Viability Of Malted Rice, Bernardo Pontes Guimaraes

Graduate Theses and Dissertations

Climate change threatens the global supply of malting barley, creating a need for sustainable, climate-resilient alternative grains for the brewing industries. This dissertation investigated the chemical, sensorial, practical, and economic viability of using rice as a malting material. First, the malting and brewing qualities of 20 rice samples were evaluated. Results indicated malted rice (MR) had good malting and brewing qualities, including adequate levels of free amino nitrogen (FAN), high amyloglucosidase and limit dextrinase activities. Furthermore, pigmented rice varieties displayed a novel reddish-purple wort color. To identify rice cultivars suited for malting and brewing, the relationship between starch chemistry and …

The Effect Of Including A Yeast Culture Containing Essential Oils In Receiving Cattle Diets On Growth Performance And Health, Taylor Deanna Foster

Animal Science Undergraduate Honors Theses

Due to the increased risk of bacterial populations developing resistance to current antibiotics, consumer perceptions surrounding the utilization of antibiotics use in cattle, and the endemic incidence of bovine respiratory disease (BRD) among growing and finishing cattle, alternative management strategies to improve the health of cattle must be developed. The objective of this study was to evaluate the use of a supplement containing a yeast culture and an essential oils blend (YEO) on the health and growth performance of stocker calves at high-risk for BRD. Crossbred male beef calves (n = 185) received on two separate dates were used in …

Influence Of Increased Supplementation Of Organic-Complexed Zinc To Beef Cows During Gestation: Effects On Preweaning Health Of Offspring, Naija N. Sharpley

Animal Science Undergraduate Honors Theses

The objective of this study was to determine the effect of increasing zinc supplementation from organic-complexed sources to beef cows during gestation on calf performance. In May 2025, during gestation, Angus crossbred cows were confirmed pregnant with female sexed semen (n = 83) and enrolled in the current study. Cows (4.7 ± 2 years of age and 531 ± 84.4 kg body weight, mean ± standard deviation) were allotted to 4 groups (20 to 21 cows/group) based on, sire of heifer calf, cow age, and cow body weights taken at weaning. Assigned groups received 1 of 2 treatments (2 groups/treatment): …

Hormonal, Cytokinetic, And Skeletal Response To A Single Weighted Vest Exercise Treatment: A Pilot Study To Determine Weighted Vest “Rucking” Treatment For Osteoporosis In Post-Menopausal Women, Eleanor Pell

Master's Theses

Osteoporosis is characterized by a deteriorating of bone tissue leading to brittleness and increased fracture risk that affects both men and women as they age. Postmenopausal women are of particular interest due to high risk of declining bone density, a characteristic of this population. Treatments for osteoporosis range from menopause hormone therapy, bisphosphonates, biologics, nutritional changes, and exercise. Load bearing exercise interventions have shown effectiveness for stimulating bone growth, but many factors such as lack of access, motivation, self-confidence or knowledge, prevent long term compliance. “Weighted vest rucking” refers to a variation of rucking, which is a form of exercise …

Sorghum Grain Secondary Metabolites And Underlying Genetics To Reduce Foodborne Pathogens In Poultry, Maria A. Conti

All Dissertations

The rise in antibiotic-resistant pathogens poses a threat to the poultry industry's ability to maintain animal health, prompting growing interest in alternatives to synthetic antibiotics. The use of non-tannin sorghum [Sorghum bicolor (L.) Moench] in poultry rations offers a valuable alternative, as this cereal grain has a high bioactive profile that can provide health benefits, including antimicrobial (AM) activity. The scope of this study was to examine the AM potential of non-tannin sorghum grain against Clostridium perfringens, a major foodborne pathogen that negatively impacts poultry health and production. To that end, the inhibitory effects of a non-tannin sorghum …

Exploring Exercise Motivation And Mental Well-Being In College Students, Elaine M. Lindesmith, Anqi Deng Dr

Health, Human Performance and Recreation Undergraduate Honors Theses

This study examined the relationship between physical activity, exercise motivation, and mental well-being among 48 undergraduate students at the University of Arkansas. Guided by Self-Determination Theory, the study used survey data to measure depression, anxiety, physical activity, and open-ended exercise motivation responses. Motivation responses were coded as autonomous or controlled.

Results showed that physical activity was weakly and negatively related to depression and anxiety, but these relationships were not statistically significant. There were also no significant differences in mental health between autonomous and controlled motivation groups, and motivation did not significantly predict mental health outcomes in regression analyses. Overall, the …

Cross-Facility Reliable Deep Learning Based Beef Marbling Assessment Via Unsupervised Domain Adaptation Regression, Samuel Vinson

Biological and Agricultural Engineering Undergraduate Honors Theses

Inconsistent quality grading in beef production leads to inefficiencies, economic disparity, and consumer mistrust. While USDA meat grading traditionally relies on skilled visual inspectors, these human evaluations suffer from cross-facility variability and subjectivity. This paper introduces the first known application of unsupervised domain adaptation regression for cross-facility beef marbling score prediction—an innovation that improves generalization across diverse environments in the beef supply chain. Utilizing numerical scores ranging from 100-900, the research employed convolutional neural networks (CNNs), including ResNet, VGG, and AlexNet architectures. The study specifically introduced and validated a unified unsupervised domain adaptation regression method using the ResNet-50 architecture to …

Analysis Of The Effects Of Astaxanthin On Human Colorectal Cancer Cells, Kara A. Walters

Theses/Capstones/Creative Projects

Astaxanthin (AXT) is an antioxidant carotenoid that is produced by the microalgae Haemococcus pluvialis. This supplement is best known for its potential health benefits including anti-inflammatory, antitumor, immunomodulatory, anticancer and antidiabetic activities. Astaxanthin is marketed as an oral dietary supplement and is widely used in the nutraceutical industry as well as a coloring agent in the food industry. Since Astaxanthin has been increasingly popular as a dietary supplement, cytotoxicity is relevant to consumer exposure. Obtaining the IC50, the concentration that inhibits 50% of cell growth, is important to find how Astaxanthin may interact with cancer, and this can be found …

College Of Natural Sciences Spring Newsletter, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

[Page 1] Dean's Message
[Page] 2 Awards & Recognitions // Student Spotlights
[Page] 3 Zhang Named to Landsat Science Team // The Power of Teaching
[Page] 4 “Science as Art” Competition Welcomes High School Artists
[Page] 5 Testing for “Forever Chemicals” in Surface Water // New Faculty Spotlight
[Page] 6 Ambassador Initiated Outreach
[Page] 7 57th Annual Geography Convention
[Page] 8 Twice the Impact on On Call with the Prairie Doc
[Page] 9 Making Staple Foods Healthier // Halaweish & Cole-Dai Retire
[Page] 10 Drone Day 2026
[Page] 11 Student Research, Scholarship, and Creative Activity Day (SRSCAD)
[Page] 12 Ceremony …

Sensing Rna’S Conformation With A Solid-State Nanopore Device At Various Ph And Temperature, Haopeng Li

Graduate Theses and Dissertations

This study uses solid-state nanopore technology to investigate the stability and dynamics of RNA molecules under thermal stress and pH fluctuations. Two distinct mRNA samples were analyzed: (1) heat shock protein (HSP)-encoding mRNA extracted from Sulfolobus solfataricus P2, a thermophilic archaeon inhabiting extreme environments such as geothermal sulfuric hot springs (pH < 4, temperature range: 65–90°C), and (2) total RNA extracted from White Leghorn chickens, which thrive under standard physiological conditions. ΦX174 virion single-stranded DNA (ssDNA) were included as a comparative reference. Nanopores, fabricated in silicon nitride membranes, were used to electrically characterize the structural properties of individual RNA molecules in solution, close to their native environments. The nanopore membrane separates two chambers containing salt buffer solution, where ionic current is the primary measurement parameter. When a voltage bias is applied across the membrane, ion flow and an ionic current can be measured. Charged RNA molecules driven translocation through the nanopore induces pore resistance changes, resulting in detectable current blockade events. Variations in these events provide insights into RNA secondary structure and conformational dynamics. By systematically altering pH and temperature, this study elucidates the effects of environmental stressors on RNA stability and structural integrity. The findings reveal distinct responses between thermophilic HSP-encoding mRNA and mesophilic RNA, underscoring the adaptive mechanisms of thermophilic RNA under extreme conditions. These results contribute to a better understanding of RNA behavior under stress and establish a foundation for future applications in RNA-based diagnostics and biotechnology development.

Consumer Perceptions Of Fda Front-Of-Package Nutrition Labeling, Madison Price

Graduate Theses and Dissertations

The U.S. Food and Drug Administration (FDA) proposed a front-of-package nutrition labeling (FOPL) rule in early 2025 to help consumers more quickly and easily compare the nutritional quality of packaged foods (U.S. Food and Drug Administration, 2025). FOPL is gaining attention as a way to encourage healthier eating habits and consumer choices, but there is still debate over which label format works best. The objective of this study was to examine consumer perceptions, understanding, and trust of FDA FOPL, and to determine how these labels impact purchasing behavior and nutritional decision-making. Data were collected via an online Qualtrics survey distributed …

Improving Genomic Prediction For Feed Efficiency Traits In Beef Cattle Using Microbiome As An Intermediate Omics, Egodage Bhagya Sewwandi Samarakoon

Department of Animal Science: Dissertations, Theses, and Student Research

Feed efficiency traits, including feed conversion ratio (FCR), average daily gain (ADG), and average daily dry matter intake (ADDMI), are economically important in beef cattle production. Emerging evidence suggests that host genetics influences feed efficiency traits through the microbiome. This study evaluates the integration of microbiome data as an intermediate layer in the Neural Network Mixed Model (NNMM), which hierarchically models genotype–microbiome–phenotype relationships as a unified regulatory network to improve genomic prediction accuracy. To reduce the computational burden of NNMM, microbiome features dimension were reduced using principal component analysis (PCA) and direct feature selection of top-ranked open reading frames (ORFs) …

The Detection Of Morbidity Using A Remote Sensing Ear Tag On Newly Received Steers And Feedlot Performance And The Effects Of Feeding Experior And Optaflexx On Carcass Characteristics And Meat Tenderness In Beef Steers, Lauryn O. Smidt

Department of Animal Science: Dissertations, Theses, and Student Research

Two experiments were conducted to evaluate the effects of remote sensing health technology and growth-promoting feed additives on feedlot cattle performance, health outcomes, and carcass characteristics. In the first study, 638 crossbred steers (initial BW = 270 kg; SD = 18.6 kg) were used in a randomized block design to assess the effectiveness of a remote sensing ear tag (RST; HerdDogg, Seward, Nebraska) versus conventional pen-rider observation (PR) for detecting morbidity during a 35-d receiving period and subsequent 180-d finishing period. No differences were detected between PR and TAG for ending BW, average daily gain (ADG), dry matter intake (DMI), …

Carcass Mass And Cooling Dynamics As Determinants Of Beef Color, Tenderness, And Dark-Cutting Risk, Grace C. Johnson

Department of Animal Science: Dissertations, Theses, and Student Research

Discoloration in beef has important implications to the beef industry. Dark-cutting (DC) beef remains one of the most economically significant color defects; however, industry prevalence has only marginally declined (≈ 0.1%) despite mitigation efforts. This lack of improvement largely stems from research focused on pre-harvest stress and glycogen depletion leading to dark, firm, and dry (DFD) beef. However, not all darkcutting beef originates from DFD phenotypes. Atypical dark-cutting (ATDC) phenotypes have recently been observed and do not exhibit the classic metabolic indicators of DFD. This trend coincides with steadily increasing carcass weights in the beef industry and raises the possibility …

Understanding Roma Oppression In Europe Through Humantarian Forensic Analysis, Christal L. Quinn

Department of Anthropology: Theses and Student Research

This thesis examines the marginalization of Roma people in Europe, and how humanitarian forensic practices may help Roma communities in their quest for justice and recognition. The study draws exclusively on secondary information to examine the social, political, and legal issues affecting the Roma communities, who have endured centuries of institutional discrimination, marginalization, and violence. This thesis identifies ways in which systematic oppression continues to limit Roma communities’ access to education, housing, healthcare, and legal protection through a review of relevant literature and applicable theoretical frameworks. The study also examines the relevance of forensic science, particularly its humanitarian applications, in …

Rehumanizing Anatomized Individuals: Using Osteobiographies As A Step Towards Reparative Justice, Lillie C. Turpin

Department of Anthropology: Theses and Student Research

In 1985, India banned the export of human remains. This ended the major trade route for primarily US and European anatomical supply companies. Until this point, companies like Carolina Biological Supply exploited and erased vulnerable people's identities, molding them into anonymous anatomical specimens. This study investigates the life and postmortem history of twenty-five individuals, previously used as anatomical specimens, housed at the University of Nebraska–Lincoln. Using an osteobiographical approach, this research reconstructs aspects of these individuals' lived experiences and examines how anatomical preparation practices reflect structural violence and apathy.

Skeletal analysis of twenty-five individuals revealed a range of biological profiles, …

Monitoring Biodiversity Growth In An Oyster Reef Restoration: Understanding How Oyster Reef Life Cycle May Impact Biodiversity., Gabriel A. Roses

Theses and Dissertations

Oyster reefs are vital to marine ecosystem health, improving water quality and providing food and habitat for diverse species. We assessed biodiversity changes for a proposed oyster reef restoration site to help guide management, future assessment, and deepen understanding of how oyster reefs function and their ecosystems dynamics.

Effects Of Vitamin E Deficiency On Anxiety-Like Behavior In Zebrafish With Distinct Stress Coping Styles, Areem Zahid

Theses/Capstones/Creative Projects

Stress and anxiety disorders affect millions worldwide and represent a significant public health burden. Individual differences in stress coping style and antioxidant regulation contribute to variability in stress responsiveness and anxiety-related behaviors. Oxidative imbalance has been implicated in the neurobiology of anxiety, but its interaction with inherent stress coping phenotypes remains unclear. This study examined whether long-term dietary vitamin E deficiency alters anxiety-like behaviors in zebrafish selectively bred for proactive and reactive stress coping styles. Adult zebrafish were maintained on either a vitamin E–sufficient or vitamin E–deficient diet for five months, followed by behavioral assessment using the novel tank diving …

Unveiling The Biochemical Pathway Responsible For Ankyloglossia (Tongue-Tie) By Tracking Enzymatic Activity Of Apoptosis Pathways, Becca Ringstad

Celebrating Scholarship and Creativity Day (2018-)

Ankyloglossia (Tongue-tie) is a condition that is caused by failed cellular degeneration leading to a short lingual frenulum. This short lingual frenulum tethers the tongue to the bottom palate of the mouth and leads to problems, including breastfeeding for infants, depriving them of important proteins that build the gut microbiome, strengthen the immune system, and fight off antigens. If left untreated, it leads to problems with speech articulation, airway development, and obstructive sleep apnea. Treatment involves a frenectomy, which is the release of the short lingual frenulum using surgical scissors or a laser. Ankyloglossia can occur with conditions such as …

Lipid Deposition In Beef Cattle, Kyra L. Elliott

Department of Animal Science: Dissertations, Theses, and Student Research

Both the amount and types of lipid deposition in beef cattle are key determinants of carcass value and meat quality. Amounts of intramuscular, subcutaneous, and visceral fat influence carcass grading outcomes, palatability, and composition traits that are important to beef producers as well as consumers. The objectives of this thesis were to: 1) compare beef grading camera estimates of intramuscular fat to amounts of chemically extractable lipid, 2) characterize the lipidomes of beef intramuscular fat, subcutaneous fat, and lean muscle using shotgun lipidomics, and 3) identify and characterize a novel genetic variant in cattle that may have important implications for …

Evaluation Of Maternal Bovine Appeasing Substance Administration And Feed Access Time On Finishing Cattle Performance, Behavior, And Carcass Characteristics, Carsten L. Loseke

Department of Animal Science: Dissertations, Theses, and Student Research

Novel products and bunk management techniques may significantly influence economically relevant performance metrics of feedlot cattle. The objective of the first experiment was to evaluate maternal Bovine Appeasing Substance (mBAS) administration on performance, carcass, health, and cortisol outcomes of yearling steers. Steers (n = 1,754, initial BW = 423 kg, SD = 25 kg) were received and assigned to pens for treatment allocation. Steers received either 10 mL of the mBAS or a mineral oil placebo at initial processing and reimplant. Hair samples were collected from a subset (n = 4 steers/pen) on d 0 and d 14. …

Integrating Growth Performance And Pathogen Detection To Investigate Disease Resilience In Commercial Swine, Emmalise Hope Marie Meyer

Department of Animal Science: Dissertations, Theses, and Student Research

Disease resilience is an important trait in commercial swine production, influencing both animal health and growth performance under natural disease challenge. The primary objective of this study was to integrate growth performance data with longitudinal pathogen detection to better understand factors contributing to disease resilience in commercial pigs. A population of 1,014 pigs across four batches was monitored from weaning through the grow-finish phase, with body weights collected to calculate average daily gain (ADG). Genome-wide association analyses were conducted using BayesC and BayesIM approaches to identify genomic regions associated with growth performance. Longitudinal pathogen surveillance was performed using pen-level oral …

Tail Biting In The Nursery: Evaluating Postural, Spatial, And Behavioral Differences Between Tail Biter And Victim Pigs, Storey L. Forster

Department of Animal Science: Dissertations, Theses, and Student Research

This study examined behavioral differences among pigs classified as tail biters, victims, or neutral during the nursery period. A total of 192 undocked nursery pigs were assigned to eight pens and monitored for 30 days using the NUtrack system. Tail biting events were identified from video observations, and pigs contributing to the top 25% of observed tail biting activity were classified as tail biters. Based on weekly tail scoring, pigs assigned a maximum tail injury score ≥ 2 were classified as victims. All other pigs were considered neutral. A total of 700 tail biting events were observed. Thirty-eight pigs …

Application Of High-Pressure Processing To Improve The Color Of Dark Beef, Kara Ann Reynolds

Department of Animal Science: Dissertations, Theses, and Student Research

Deviation of beef from the bright cherry-red color preferred by consumers is often discounted or discarded at retail, resulting in substantial annual economic loss to the beef industry. One such deviation is dark cutting beef, which is characterized by a darker lean appearance that is undesirable to consumers and often rejected. Similarly, beef from mature cattle tends to exhibit a darker surface color, which can also reduce consumer acceptability. High-Pressure processing (HPP) has been investigated as a strategy to improve the color of dark cutting beef. Previous studies have focused on identifying pressure levels and holding times that optimize color …