Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Life Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 3091 - 3120 of 44868

Full-Text Articles in Entire DC Network

Quantifying Modifiable Lifestyle Behaviors And Influences Associated With Preventable Cancers In Selected Rural Counties: A Mixed Method Study, Jecinta Scott Jan 2025

Quantifying Modifiable Lifestyle Behaviors And Influences Associated With Preventable Cancers In Selected Rural Counties: A Mixed Method Study, Jecinta Scott

Dissertations and Theses

Cancer is the second leading cause of death in the United States disproportionately affecting rural communities. This dissertation study investigates the involvement of rural communities in lifestyle behaviors associated with increased risk of cancers, the impact of socioeconomic factors, and what influences their behavior and the impact of political party affiliation. The study was conducted using a mixed-method quantitative data analysis enhanced by qualitative interviews. It began with an extensive literature review to identify existing research, and evidence gaps on the topic. Data collection involved retrospective quantitative extraction from the Centers for Disease Control and Prevention’s Behavioral Risk Factor Surveillance …


Understanding Food Insecurity Among International Students At Ohio University, Kyle Butler, Joshua Osondu Jan 2025

Understanding Food Insecurity Among International Students At Ohio University, Kyle Butler, Joshua Osondu

Sustainable Living Hub Reports and Publications

Recently, food insecurity has emerged as a concern among the student body of Ohio University (OHIO), particularly among its international graduate students. This survey study was undertaken to provide data to inform OHIO’s response to food insecurity among its international graduate students.


The Effects Of A History Of Child Trauma On Breastfeeding Outcomes, Emily Flynn Jan 2025

The Effects Of A History Of Child Trauma On Breastfeeding Outcomes, Emily Flynn

Graduate Research Theses & Dissertations

Breastfeeding provides significant health benefits for both parent and child, yet many parents discontinue earlier than recommended. While childhood sexual abuse has been associated with breastfeeding difficulties, limited research has examined the broader effects of other forms of childhood maltreatments on breastfeeding outcomes. This cross-sectional study examined the relationship between a history of childhood trauma and breastfeeding outcomes, with social support explored as a potential moderator. Participants (n = 194) were birthing parents of children under the age of five, recruited from online parenting communities. Measures included the Adverse Childhood Experience International Questionnaire (ACE-IQ), a breastfeeding duration item, and a …


Modeling Wild Rice Bed Health: A Dual Metric Approach For Bed Strength And Invasive Impact, Seth Sisneros-Martinez Jan 2025

Modeling Wild Rice Bed Health: A Dual Metric Approach For Bed Strength And Invasive Impact, Seth Sisneros-Martinez

Journal of Earth and Life Science

Wild rice (mannoomin; Zizania palustris) is an aquatic grain that grows in slow-moving rivers and shallow bays throughout northern Minnesota. In Headquarters Bay on Leech Lake, wild rice has served as a cultural staple for Indigenous communities for centuries. However, its population has declined in recent years due to multiple environmental issues. One potential contributor is Eurasian watermilfoil (Myriophyllum spicatum; EWM), an invasive species that forms dense mats capable of outcompeting native aquatic vegetation, including wild rice. EWM was first recorded on the southern shoreline of Leech Lake in 2005 and has since become widespread. This study …


René Dubos: An Annotated Bibliography, Carol L. Moberg Jan 2025

René Dubos: An Annotated Bibliography, Carol L. Moberg

René Dubos: An Annotated Bibliography

René Dubos (1901–1982), a prominent 20th century scientist, humanist, and philosopher, was a prolific author. Affiliated for more than 50 years with The Rockefeller Institute for Medical Research/The Rockefeller University, his studies ranged from antibiotics and the role of bacteria in human diseases to formulating broad ecological and environmental questions affecting human health and disease. His seminal writings explore a lifelong belief that a living organism—whether microbe, human being, society, or the Earth itself—could be understood only through its relationships with everything else.

This comprehensive bibliography of more than a thousand works by René Dubos includes brief annotations for each …


A Neuronal Circuit Motif For Leaky Vector Integration, Abby Janke Jan 2025

A Neuronal Circuit Motif For Leaky Vector Integration, Abby Janke

Student Theses and Dissertations

To efficiently navigate their environments, animals ranging from insects to humans can keep track of their trajectory by continuously summing their direction and distance traveled over time. It is not clear how brains perform this fundamental computation––known as path integration––even though neural correlates and computer models abound. In arthropods, spatial-cognition related processes such as path integration are thought to be implemented in the central complex. Experimenters have shown that contiguously arrayed populations of neurons in the Drosophila fan-shaped body, a substructure of the central complex, display sinusoidally shaped bumps of calcium activity that signal vectors relevant for spatial navigation. The …


Impact Of Glufosinate On Soil Microbial Community Dynamics, Sarobi Das Jan 2025

Impact Of Glufosinate On Soil Microbial Community Dynamics, Sarobi Das

Biology Dissertations - Archive

The increasing global regulations of glyphosate due to its possible carcinogenicity and environmental hazards have necessitated the search for alternative herbicides. Glufosinate-ammonium offers a sustainable attribute due to its low toxicity and limited reported herbicide resistance cases. Despite its increasing agricultural importance, very limited studies are done on its environmental impact, especially on the soil systems. This thesis examines the ecological behavior of glufosinate in soil, precisely focusing on its effect on the dynamics of soil microbiome and the potential use of Bradyrhizobium japonicum USDA110 for bioremediation by reversing the effect of microbial dysbiosis. A series of 30-day mesocosm studies …


Principles Of Biomedical Research, Faina Linkov, Matthew C. Kostek Jan 2025

Principles Of Biomedical Research, Faina Linkov, Matthew C. Kostek

Open Education Materials

HLT 430/530

CC BY-NC-SA


Effects Of Starter Cultures On The Metabolite Profile, Antioxidant Activities, And Anti-Aging Properties Of Tapuy Lees, Edward Kevin B. Bragais, Paul Mark B. Medina Jan 2025

Effects Of Starter Cultures On The Metabolite Profile, Antioxidant Activities, And Anti-Aging Properties Of Tapuy Lees, Edward Kevin B. Bragais, Paul Mark B. Medina

Biology Faculty Publications

The Philippine rice wine (tapuy) and tapuy lees making process utilizes bubod, the traditional starter culture. The bubod contains variable number and species of microorganisms and influences the physical and chemical properties of tapuy and tapuy lees, resulting in inconsistent quality products. Hence, improvement and standardization of local starter culture are significant. Here, we examined the effects of well-defined starter cultures (Rhizopus oryzae (RO), Mucor indicus (MI), and Saccharomyces cerevisiae (SC)) and bubod on the metabolite profile, antioxidant, and anti-aging activities of tapuy lees. Our results showed the presence of polyphenols (102.36 ± 2.84 to 173.92 …


Movement And Activity Of Burbot, (Mizay; Lota Lota) In A Spring-Fed Minnesota Lake, Abigail M. Fountain Jan 2025

Movement And Activity Of Burbot, (Mizay; Lota Lota) In A Spring-Fed Minnesota Lake, Abigail M. Fountain

Biology Graduate Theses

Burbot (Mizay; Lota lota) are a relatively unmanaged freshwater fish, important in many local Indigenous cultures, but often overlooked or maltreated in research, conservation, and fishing practices. As such, relatively little research has been conducted on Burbot, despite ecological significance as an indicator species. A recent resurgence in popularity as a target species, however, has prompted new research to inform management policies. The objectives of this study were to summarize Burbot movement by identifying patterns in swimming activity and identify possible predictors of the movement observed. This study investigated the movements of 39 individuals implanted with acoustic transmitters in Bad …


Novel Infection By Mucor Hiemalis Kills Caenorhabditis Hosts Through Intestinal Perforation, Jay Ni Jan 2025

Novel Infection By Mucor Hiemalis Kills Caenorhabditis Hosts Through Intestinal Perforation, Jay Ni

West Chester University Graduate Theses, Dissertations, and Final Projects

The nematode Caenorhabditis elegans has emerged as a popular model system to investigate cell biology and host-pathogen interactions. Presently, C. elegans is studied as a natural host of intracellular pathogens such as microsporidia and Orsay virus along with extracellular bacterial and fungal pathogens. The use of C. elegans as a model in host-pathogen research is limited by the number of naturally occurring pathogens to the organism. Through a sampling project to identify new pathogens of C. elegans, we identified the fungus Mucor hiemalis as a pathogen of Caenorhabditis species. We observed the fungus in the intestinal lumen of wild-caught …


Forage News [2025-01], University Of Kentucky Jan 2025

Forage News [2025-01], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-02], University Of Kentucky Jan 2025

Forage News [2025-02], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-12], University Of Kentucky Jan 2025

Forage News [2025-12], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-10], University Of Kentucky Jan 2025

Forage News [2025-10], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-09], University Of Kentucky Jan 2025

Forage News [2025-09], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-08], University Of Kentucky Jan 2025

Forage News [2025-08], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-06], University Of Kentucky Jan 2025

Forage News [2025-06], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-05], University Of Kentucky Jan 2025

Forage News [2025-05], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-04], University Of Kentucky Jan 2025

Forage News [2025-04], University Of Kentucky

Forage News

No abstract provided.


Forage News [2025-03], University Of Kentucky Jan 2025

Forage News [2025-03], University Of Kentucky

Forage News

No abstract provided.


Astrovascular Decoupling In Awake 5×Fad Mice Is Associated With Reduced Astrocytic Calcium, Ruei-Lung Lin, Sophiya L. Sims, Nicholas A. Wright, Léopoldine B. Galopin, Blaine Weiss, Susan D. Kraner, Jacquelyn E. Rhinehart, Ting-Hsuan Lu, Pradoldej Sompol, Christopher M. Norris, Olivier Thibault Jan 2025

Astrovascular Decoupling In Awake 5×Fad Mice Is Associated With Reduced Astrocytic Calcium, Ruei-Lung Lin, Sophiya L. Sims, Nicholas A. Wright, Léopoldine B. Galopin, Blaine Weiss, Susan D. Kraner, Jacquelyn E. Rhinehart, Ting-Hsuan Lu, Pradoldej Sompol, Christopher M. Norris, Olivier Thibault

Pharmacology and Nutritional Sciences Faculty Publications

INTRODUCTION

Evidence points to dysregulated Ca2+ in neurons and astrocytes in models of amyloidosis. While most of these data were obtained in vitro or in vivo under anesthesia, less work has investigated these variables in awake ambulating mice.

METHODS

Astrocytic Ca2+ fluctuations (GCaMP8f) were imaged concomitantly with vasoreactivity in S1 on a two-photon microscope during rest and ambulation. Single-cell resolution variables were extracted using continuous wavelet transform and traditional ΔF/F measures.

RESULTS

Along with increases in amyloid beta (Aβ) accumulation, we found significant reductions in measures of astrocyte functional connectivity, pairwise correlations, and network synchronicity in older 5×FAD …


Impact Of Overwinter Gain On Growth And Reproductive Performance In March-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy Jan 2025

Impact Of Overwinter Gain On Growth And Reproductive Performance In March-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy

Nebraska Beef Cattle Reports

Summary with Implications

Heifers developed to lower rates of overwinter gain may reduce development costs without growth and reproduction impacted. A 3-year study was conducted to evaluate different overwinter rates of gain on heifer growth rates, reproductive, and economic performance. Heifers were managed together and individually supplemented (January-May) with dried distillers grains to achieve either a low (0.75 lb/d) or high (1.50 lb/d) average daily gain. At breeding, high gain heifers were heavier than low gain heifers. Average daily gain and body condition score were similar between treatments. Overwinter treatment did not impact attainment of puberty, pregnancy rates, or the …


Interaction Of Backgrounding System And Implant Use On Growing Calf Performance, Sydney T. Vanderhoff, Braden C. Troyer, Rebecca L. Mcdermott, Mitchell M. Norman, Brandon L. Nuttelman, Galen E. Erickson, Mary E. Drewnoski, James C. Macdonald Jan 2025

Interaction Of Backgrounding System And Implant Use On Growing Calf Performance, Sydney T. Vanderhoff, Braden C. Troyer, Rebecca L. Mcdermott, Mitchell M. Norman, Brandon L. Nuttelman, Galen E. Erickson, Mary E. Drewnoski, James C. Macdonald

Nebraska Beef Cattle Reports

Summary with Implications

A two-year study utilized 480 weaned steers each year targeted to gain either 1 or 2 lb/d during the winter followed by ad libitum forage intake during the summer to determine the effects of winter rate of gain and implant strategy during the winter backgrounding and summer phases on steer performance, forage intake, and compensatory gain. During the winter, steers received a Revalor-G or no implant. In the summer, steers either received a Revalor-IS or no implant. The use of Revalor-G and increased rate of gain during the winter backgrounding phase had additive effects to increase animal …


2025 Beef Cattle Report Jan 2025

2025 Beef Cattle Report

Nebraska Beef Cattle Reports

Cow-calf Nutrition, Reproduction, and Management

Artificial Insemination of Beef Heifers with Multi-sire Semen, Dempster M. Christenson, Jordan M. Thomas, Daniel J. Kelly, Rick N. Funston

Impact of Overwinter Gain on Growth and Reproductive Performance in March- born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. McCarthy

Impact of Pre- and Post-breeding Supplementation on Performance of May-born Heifers, Josie N. Crouch, J. Travis. Mulliniks, Jacki A. Musgrave, Kacie L. McCarthy

Growing Calf and Yearling Management

Effects of Allocation Frequency on Cattle Performance and Forage Utilization when Swath Grazing a Sorghum-Sudangrass Hybrid in Eastern Nebraska, Thomas E. Aquino, …


Advancing Clinical Trial Readiness In White Matter Disease And Related Dementias: Key Steps For Future Research Progress, Pradoldej Sompol, Gregory A. Jicha, Jason D. Hinman, Adam M. Brickman, Steven M. Greenberg, Konstantinos Arfanakis, Marion S. Buckwalter, Irene Lorenzo Llorente, Jeff D. Williamson, Michael S. Wolf, Eric E. Smith, Aditi Gupta, Margaret E. Flanagan, Miguel A. Vazquez, Jeffrey M. Burns, S. Thomas Carmichael, Frank C. Barone Jan 2025

Advancing Clinical Trial Readiness In White Matter Disease And Related Dementias: Key Steps For Future Research Progress, Pradoldej Sompol, Gregory A. Jicha, Jason D. Hinman, Adam M. Brickman, Steven M. Greenberg, Konstantinos Arfanakis, Marion S. Buckwalter, Irene Lorenzo Llorente, Jeff D. Williamson, Michael S. Wolf, Eric E. Smith, Aditi Gupta, Margaret E. Flanagan, Miguel A. Vazquez, Jeffrey M. Burns, S. Thomas Carmichael, Frank C. Barone

Pharmacology and Nutritional Sciences Faculty Publications

White matter disease, a broad-spectrum term that covers various types of white matter lesions and degeneration, is strongly related to age-related neurodegenerative disorders including Alzheimer’s disease (AD), and vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer’s related dementias (ADRD). There is no specific treatment for white matter disease. Therefore, basic research and clinical studies are essential for future outcomes. Since its formation in 2020, the Albert Research Institute for White Matter and Cognition (ARIWMC) mission has been to support white matter research by providing a forum for communication where basic and clinical scientists meet to discuss and debate …


We Found Love In A Wetter Climate: The Impact Of Varying Climatic Conditions On The Prevalence Of A Fungal Endophyte In Elymus Virginicus Populations, Audrey Yung Jan 2025

We Found Love In A Wetter Climate: The Impact Of Varying Climatic Conditions On The Prevalence Of A Fungal Endophyte In Elymus Virginicus Populations, Audrey Yung

Scripps Senior Theses

Epichloë is a genus of endophytes– symbiotic fungi residing within a plant’s tissue– that can provide mutualistic benefits to its host. The stress gradient hypothesis predicts that mutualism between species becomes stronger in conditions of high abiotic stress. We tested this idea by assessing how Epichloë prevalence in Elymus virginicus populations is affected by varying climatic conditions. We established plots of E. virginicus with known endophyte frequencies in the spring of 2023 at five sites across a precipitation gradient in Texas and Louisiana. We collected E. virginicus recruits in June and July 2024 at all field sites. To determine recruits’ …


Computational Analysis And Characterization Of The Inducible 1-Cysteine Peroxiredoxin Promoter In The Malaria Parasite Plasmodium, Lara Ladney Jan 2025

Computational Analysis And Characterization Of The Inducible 1-Cysteine Peroxiredoxin Promoter In The Malaria Parasite Plasmodium, Lara Ladney

Dissertations

Malaria afflicts over 200 million people annually, which results in over half a million deaths, primarily in sub-Saharan Africa. Malaria parasites are complex protozoan organisms that inhabit two hosts: humans, the site of asexual reproduction, and the Anopheles mosquito, where sexual reproduction occurs. To withstand the hostile extracellular environment of the Anopheles mosquito, the malaria parasite Plasmodium berghei employs antioxidant defense mechanisms. Previous work suggests upregulation of 1-Cysteine Peroxiredoxin (1-CPxn) when the mosquito uptakes a blood meal containing the parasite. The parasite must acclimate to the harsh environmental conditions of the mosquito midgut: find a way to counteract reactive oxygen …


Genetic Analysis Of Methionine Restriction-Associated Mitochondrial Unfolded Protein Response Signaling., Josh D. Dodge Jan 2025

Genetic Analysis Of Methionine Restriction-Associated Mitochondrial Unfolded Protein Response Signaling., Josh D. Dodge

Biology Dissertations - Archive

The lifespan of an organism is dictated by various genetic and environmental factors. One such determinant is the health of mitochondria which are organelles that mediate various critical cell functions including a significant role in generating the vast supply of cellular energy. Indeed, the gradual decline of mitochondrial function is believed to be a hallmark and possible cause of aging. Paradoxically, mild mitochondrial dysfunction early in life extends lifespan in various model organisms. Cells use diverse approaches to promote mitochondrial homeostasis, including the transcriptional reprogramming of cells by mitochondrial unfolded protein response (UPRmt) to mitigate mitochondrial stress. Consistently, UPRmt activation …


The Role Of Sodium Butyrate As An Inflammatory Regulator And Its Effect On Long Noncoding Rnas In Neuroinflammation, Angel Covarrubias Jan 2025

The Role Of Sodium Butyrate As An Inflammatory Regulator And Its Effect On Long Noncoding Rnas In Neuroinflammation, Angel Covarrubias

Chemistry & Biochemistry Theses - Archive

Inflammation is a crucial homeostatic process that contributes to both the elimination of foreign invaders and tissue repair. Inflammation at sites of tissue injury or infection is initiated by the detection of a harmful stimulus, triggering vital inflammatory immune signaling pathways and a cascade of cytokines and inflammatory mediators. The dysregulation of this process, however, can result in inappropriate inflammatory responses manifesting in tissue damage and compromised cell function. Dysregulation of the inflammatory response is seen frequently in many human diseases such as Diabetes, Cancer, cardiovascular disease, and neurodegenerative diseases.

In the context of the Central Nervous system, inflammation is …