Digital Commons Network^™

Comparative Analysis Of Artificial Intelligence (Ai) Implications For Active Learning And Assessment At Various Curricular Levels Of Stem And Health Sciences In Developed Versus Underprivileged Countries, Vinay Munlapudi, Santanu De

FDLA Journal

Today’s all-pervasive emergence of artificial intelligence (AI) necessitates a comprehensive evaluation of its role in education, especially for occupational disciplines in health sciences and STEM. AI has reshaped student learning and instructors’ navigation of the evolving, post coronavirus infectious disease (COVID-19) global academic landscape. This study aimed at encapsulating evidence-based AI implications for student-centered, active learning and assessment at various curricular levels of science, technology, engineering, mathematics (STEM) and health sciences education in developed versus underprivileged or less developed countries. An extensive, scoping review of 65 recent, scholarly publications was conducted over six months through diverse search engines (PubMed, Google …

Fraction-Seq: An Integrated Experimental And Computational Workflow For Determining The Localization And Abundance Of Small Non-Coding Rnas In Subcellular Compartments, Siddhartha Shah, Tess Cherlin, Yi Jing, Stepan Nersisyan, Benjamin E. Leiby, Isidore Rigoutsos

Computational Medicine Center Faculty Papers

Small non-coding RNAs (sncRNAs) have garnered considerable attention in recent years, following accumulating evidence of their critical roles in many cellular processes. Among sncRNAs, microRNAs (miRNAs) and their isoforms (isomiRs), tRNA-derived fragments (tRFs), rRNA-derived fragments (rRFs), and Y RNA-derived fragments (yRFs) account for more than 95% of all sncRNAs found in cells. Despite their critical regulatory roles, most sncRNAs remain uncharacterized because their functionalization is a lengthy and challenging undertaking. Knowing an sncRNA's abundance helps prioritize among the various choices, while knowing where it localizes in the cell greatly limits the number and identity of its potential targets and helps …

Dry After-Ripening Increases Germination Of Critically Imperilled Physaria Thamnophila (Zapata Bladderpod), Christopher A. Gabler, Jerald T. Garrett

School of Earth, Environmental, & Marine Sciences Faculty Publications

Effective endangered plant conservation and recovery require empirical knowledge of seed dormancy release and responses to post-collection handling, yet such information is lacking for many rare taxa. Physaria thamnophila (Zapata bladderpod; Brassicaceae), a critically imperilled (G1) species endemic to southern Texas, USA, is poorly studied, and basic questions regarding seed storage and germination remain unresolved. We evaluated the effects of short-term cool-storage duration (14–180 d), storage temperature (refrigeration vs. freezing), dry after-ripening and maternal plant identity on germination probability and timing in P. thamnophila. Dry after-ripening and increased cool-storage duration consistently increased germination and shortened germination time, whereas storage temperature …

Changes In Water Quality And Microbiota Over Two Years In Florida Hard Clam (Mercenaria Mercenaria) Hatcheries, Bonnie Getter

Electronic Theses and Dissertations 2020 - Present

This thesis characterized the water quality and bacterial communities in nine hard clam hatcheries over two production years through weekly or biweekly water quality and chemistry monitoring, monthly bacterial plating in the second year of production, and select 16S microbiome sampling at select hatcheries to address production bottlenecks and support the reliable production of high-quality seed for Florida’s growing hard clam aquaculture industry. Logistic regression models showed that water source was distinguished by pH, salinity, alkalinity, and nitrite, whereas geographic location was distinguished by temperature, salinity, nitrate, and calcium; temperature, dissolved oxygen, salinity, and alkalinity distinguished seasons. Vibrio bacteria differed …

Influence Of Transboundary Wildfire Smoke On Fine Particulate Matter Concentrations At South Texas Border Schools, Sai Deepak Pinakana, Kabir Bahadur Shah, Owen Temby, Dawid K. Wladyka, Juan L. Gonzalez, Md Saydur Rahman, Katarzyna Sepielak, Amit U. Raysoni

School of Earth, Environmental, & Marine Sciences Faculty Publications

Exposure to air pollutants in indoor and outdoor school environments poses significant health risks to children due to their heightened vulnerability. Increasing wildfire frequency has intensified transboundary smoke transport, with border communities among the first to experience associated air quality impacts. While the impacts of wildfires on air quality are increasingly recognized through satellite observations and modeling, ground-based observations remain scarce in under-monitored regions. Low-cost air sensors were deployed across schools in the Roma and Rio Grande City areas of Starr County, along the U.S.–Mexico border, for 146-days from November 2023 to April 2024. The raw sensor measurements were corrected …

Crystal Structure Of New Polar Rare Earth Borates Na2.62Ln2.12(Bo3)3 (Ln = Pr, Nd, Sm) Containing Isolated Bo3 Groups, Alevtina A. Maksimova, Mark D. Smith, Hans Conrad Zur Loye

Faculty Publications

Three new rare earth borates, Na2.62Ln2.12(BO3)3 (Ln = Pr, Nd, Sm), were synthesized via a high-temperature solution reaction using a BaCO3–H3BO3–NaF flux and structurally characterized by single-crystal X-ray diffraction analysis. The compounds crystallize in the orthorhombic space group Amm2 with lattice parameters a = 5.0985(10) Å, b = 11.180(2) Å, c = 7.1483(14) Å, and a unit cell volume of 407.48(14) ų (Z = 2) for Na2.62Pr2.12(BO3)3, a = 5.0983(10) Å, b = 11.181(2) Å, c = 7.1491(14) Å, and a unit cell volume of 407.51(14) ų (Z = 2) for Na2.62Nd2.12(BO3)3, and a = 5.08630(10) Å, b …

Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye

Faculty Publications

Sodium barium lutetium borate NaBaLu(BO₃)₂ crystals were synthesized using a high-temperature solution method. The crystal structure of this layered orthoborate is described and corresponds to that of an extensive orthoborates family, NaBaR(BO₃)₂ (R = Sc, Y, Yb, Tb – Lu). NaBaLu(BO₃)₂ was doped by Eu³⁺ and Tb³⁺ to explore its performance as a host material and to investigate the luminescent properties of the Eu³⁺ and Tb³⁺ doped materials. The emission spectra of the NaBaLu(BO₃)₂:Ln (Ln = Eu, Tb) crystals are presented. The most …

Validating The Expression Of Genes Potentially Involved In The Development Of Aggressive Melanoma Tumor In The Zebrafish Melanoma Model, Mayra Matos Diaz

Theses, Dissertations and Culminating Projects

Melanoma is an aggressive form of skin cancer characterized by rapid progression, metastatic potential, and the frequent development of resistance to targeted therapies. Although the Inducible cAMP Early Repressor (ICER) has been identified as a potential tumor suppressor in melanoma, the molecular mechanisms underlying its role in tumor progression remain poorly understood. Building upon the transcriptomic findings of Wheelan et al. (2025), this study investigates the relationship between ICER and ten candidate genes (gdf6a, pdgfra, col4a4, fgfr2, pdgfrb, cdkn1a, fgf5, akt1, met, and notch3) associated with BMP signaling. Quantitative polymerase chain reaction (qPCR) was used to compare gene expression between …

Temperature And Salinity Effects On The Physiology Of Bullfrog Tadpoles (Lithobates Catesbeianus) From A Suburban Temperate Wetland, Angela Brown

Theses, Dissertations and Culminating Projects

One of the most robust amphibians is the American Bullfrog, Lithobates catesbeianus, which is a widespread species that is invasive worldwide, and is broadly tolerant of a range of environmental conditions. Despite this tolerance, survival and performance of adult L. catesbeianus can be negatively affected by increasing temperatures and salinity resulting from anthropogenic impacts, such as climate change and road salts. This study focuses on the effects of acute salinity exposure (mimicking road salt influx into a pond) on L. catesbeianus tadpoles at different larval stages. Increased salinity was predicted to negatively affect two physiological performance measures. Critical maximum temperature …

The Aggregation Of Microplastics By Enhancing Extracellular Polymeric Substance Production In Pseudoalteromonas Sp. Ncimb 2021 To Improve Removal Efficiencies In Environmental Matrices, Janelle L. Mercer

All Theses

Microplastics (MP) are ubiquitous in the natural environment and are a growing threat due to their small size and durability. Plastics are released into the environment through improper waste management, wastewater treatment outfalls, industrial spills, agricultural runoff, and landfills. These particles breakdown into secondary MP through degradation pathways. MP, less than 5 mm, require intricate removal techniques from water systems. Filtration techniques, though viable and effective, have implementation constraints due to high cost, maintenance demands, and filter fouling. By integrating coagulation and flocculation processes prior to filtration, MP removal efficiencies can increase, while minimizing operational challenges during filtration. Extracellular polymeric …

Odyssey To The Extraordinary: Living Our Land Grant Mission And Beyond, Jeffrey P. Gold, Katherine S. Ankerson, Tiffany Heng-Moss

Institute of Agriculture and Natural Resources: Institute Publications

Presents a strategy intended to guide future directions for the University of Nebraska-Lincoln's (UNL) Institute of Agriculture and Natural Resources (IANR) including issues related to governance, funding, organizational structure, and strategic alignment within UNL and the University of Nebraska system.

Expression Levels Of Heat Shock Protein 72 And Their Correlation With Biomarkers Of Renal Function Among Hispanic Construction Workers Exposed To Ambient Heat In El Paso, Texas, Maria Fuentes

Open Access Theses & Dissertations

Heat shock proteins (HSP) are intracellular molecular proteins that are upregulated in response to cellular stress, including heat exposure. Through their protective functions, HSP help maintain protein structure, prevent protein denaturation, and preserve cellular homeostasis during states of physiological stress. Because of their cytoprotective properties, HSP have emerged as potential biomarkers for detecting early signs of tissue injury and predicting clinical outcomes associated with heat related illnesses (HRI), including acute kidney injuries (AKI). AKI is a leading cause of hospitalizations due to heat stress exposure and heat stroke. In the absence of early detection and effective therapeutic interventions, AKI may …

Performance Of The Denitrification-Decomposition Model In Simulating Agronomic Properties And N2o Emissions Under Smallholder Climate-Smart Farming Systems, Esphorn Kibet, Collins M. Musafiri, Milka Kiboi, Onesmus K. Ng'etich, David K. Kosgei, Abdirahman Zeila, Franklin Mairura, Felix K. Ngetich

All Peer-Reviewed Publications

The DeNitrification-DeComposition (DNDC) model is a crucial tool for estimating soil greenhouse gas fluxes and understanding soil-plant interactions. This study evaluates the performance of the DNDC model in simulating soil temperature, moisture, crop yield, and nitrous oxide (N2O) fluxes across different land utilization types in Western Kenya. The land utilization types included: i) agroforestry M (agroforestry with Markhamia lutea, ii) sole sorghum, iii) agroforestry L (agroforestry with Leucaena leucocephala), iv) sole maize, and v) grazing Land, each replicated thrice. Fertilizer and manure were applied as part of the management practices, with manure applied at 2t ha⁻¹. Soil greenhouse …

Determining The Role Of Maumee River Sediments In Microbial Nitrogen Transformations And Net Fluxes, Ashlyn Stanalonis

Master's Theses

The Maumee River watershed is the largest of any river feeding into the Laurentian Great Lakes and is primarily comprised of agricultural land uses. Most cultivated crops require fertilizer applications to sustain growth and productivity. Fertilizer runoff is a major source of nutrient loading to the river, and total nitrogen (N) and phosphorus (P) inputs contribute to eutrophication and cyanobacterial blooms in the western basin of Lake Erie. This study aimed to characterize Maumee River sediments as net N sinks or sources to the western basin and evaluate N removal efficiency (a valuable ecosystem service) to determine if river sediments …

Land Condition Standards For The Western Australian Nullarbor Pastoral Region, Peter-Jon A. Waddell, Wayne J. Fletcher

Natural resources published reports

This report outlines the quantitative land condition standards that define acceptable pastoral land condition for the Western Australian part of the Nullarbor, to meet the regulatory requirements of the Land Administration Act 1997 and the Soil and Land Conservation Act 1945.

The Department of Primary Industries and Regional Development is developing regional-level pastoral land condition standards for Western Australia as a critical component of the Framework for sustainable pastoral management – revised edition (Fletcher 2022), the purpose of which is to address the Office of the Auditor General’s recommendations to improve the management of pastoral lands in WA …

The Relationship Between Depression And Cognitive Proficiency Index Across Biological Sex, Angela N. Ferdinardo

Dissertations

Depression is a widely studied mood disorder, and understanding its effect on cognitive functioning has become an important area of research. While research has examined relationships among depression, working memory, and cognitive deficits, limited research has explored depressive symptoms and cognitive proficiency across biological sex. Depression manifests similarly in men and women, though men are more likely to experience irritability, impulsivity, and anger, while women tend to experience sadness, stress, and sleep disturbances (Johns Hopkins Medicine, 2023). Women are also more likely to seek treatment and cope differently than men. This study examined the relationship between depression and cognitive proficiency …

Why Technical Readiness Is Not Enough: Institutional Barriers To Full Harvest Strategy Adoption In The International Pacific Halibut Commission, Evelyn Roozee, Owen Temby, Gordon M. Hickey

School of Earth, Environmental, & Marine Sciences Faculty Publications

Harvest strategies are increasingly promoted as a mechanism to reduce political discretion and align fisheries management with pre-agreed scientific objectives. While substantial progress has been made in tuna regional fisheries management organizations (RFMOs), non-tuna RFMOs have lagged behind. Existing research has focused primarily on technical modeling challenges, with comparatively limited attention to the governance dynamics shaping adoption. Using the International Pacific Halibut Commission (IPHC) as an instrumental case study, we examine the progress and delays in the development of a harvest strategy policy (HSP) through semi-structured interviews and participant observation. We find that the IPHC successfully addressed commonly cited barriers, …

Effects Of Photosynthetic Mode On Growth In Closely Related Tillandsia Species, Jeremy L. Read

Electronic Theses, Projects, and Dissertations

To examine the effects of photosynthetic mode (C3 vs CAM) on plant productivity, subjects of the sister taxa Tillandsia confertiflora (a C3 species) and Tillandsia latifolia (a CAM species) were grown under controlled conditions via growth chamber over 30 weeks. These subjects were divided into non-stressed and drought stress groups. Subjects were compared for total biomass gained or lost over the time period as well as physiological stress measures and CAM activity. The primary conclusion is that usage of CAM does not show major differences or tradeoffs for overall productivity. Future work is needed to clarify if this holds true …

Can Kinematics Specify Tool Use Affordances?, Tyler Duffrin

All Dissertations

Object properties such as length, shape, and heaviness, as well as affordance-based properties such as strike-with-ability and poke-with-ability, can be perceived via dynamic touch as functions of inertia tensor invariants. The primary question addressed here was whether people can perceive these same power and precision properties for purely virtual objects, which lack dynamic physical forces. The Kinematic Specification of Dynamics (KSD) principle asserts that missing dynamics are lawfully specified by kinematic (visual) motion patterns, such that kinematic information alone may support successful interactions with virtual objects. In three experiments, we investigated (1) whether virtual reality (VR) users could calibrate to …

Agent-Based Modeling Of Cellular Dynamics In Adoptive Cell Therapies, Yujia Wang

Dissertations and Theses (Open Access)

Adoptive cell therapies (ACT) have shown promising progress in combating cancer, but clinical responses remain heterogeneous. Key determinants, including the functional states of infused cells, tumor–immune interactions, and dosing strategies, are difficult to resolve experimentally in the dynamic and heterogeneous tumor microenvironment, limiting optimization of ACT products and treatment regimens. To address the gap, we developed ABMACT (Agent-Based Model for Adoptive Cell Therapies), a computational framework that reconstruct key cellular functions, interactions, and molecular signatures to recapitulate cell population dynamics associated with differential treatment responses. ABMACT encodes autonomous “virtual cells” using literature-informed rules calibrated with experimental data, enabling simulation of …

Oxidative Stress Mediated Glutamate Release And Nmda Receptor-Dependent Synaptic Remodeling In Radiation-Induced Cognitive Dysfunction, Thanh Lam

Dissertations and Theses (Open Access)

In children younger than 14 years old, the brain and other parts of the central nervous system are the most common sites for solid tumors. Radiotherapy is an effective treatment for central nervous system (CNS) tumors. However, it often causes a progressive decline in cognitive functions, which is especially devastating for pediatric patients. Although post-mitotic neurons are generally considered resistant to radiation-induced immediate cell death, ionizing radiation causes complex neurochemical and structural changes that damage synaptic integrity. In this study, we examined the molecular cascades following a 10 Gy radiation dose applied to mouse cortical neurons. We found that radiation-induced …

Mutational Analysis Of Domain Functions In The Yeast Decapping Enzyme Dcp2, Jellisa Ewan, Ambro Van Hoof

Dissertations and Theses (Open Access)

In yeast, the major mRNA decay pathway involves deadenylation of the 3’ poly-A tail, followed by decapping of the 5’ m7Gppp cap and subsequent 5’ to 3’ degradation or 3’ to 5’ degradation. This is carried out by Pan2/Pan3 and Ccr4/Not deadenylases, the decapping enzyme Dcp2, and Xrn1 and  RNA exosome exoribonucleases, respectively. The eukaryotic mRNA decapping enzyme complex, Dcp1/Dcp2, is essential in yeast, and deletion of either gene is lethal. However, the deadenylases that act upstream and the 5’ exoribonuclease that act downstream of the decapping step are not, even though they are all highly conserved with no known …

Alfred Russel Wallace Notes 42: How Accurate Are The Transcriptions Presented At The Alfred Russel Wallace Page Website?, Charles H. Smith

Faculty/Staff Personal Papers

A look is taken at the level of accuracy displayed by the transcriptions of Wallace writings offered at the Alfred Russel Wallace Page website, as determined by a ChatGPT analysis.

A Comparison Of Survival, Growth, And Stress Resilience In Three Different Lineages Of The Pacific Oyster (Crassostrea Gigas) Farmed On The California Central Coast, Victoria F. Hanshaw

Master's Theses

Aquaculture of Pacific oysters on the US West Coast is routinely impacted by seasonal unexplained mortality events. To better understand these large-scale mortality events in oyster aquaculture, shellfish growers and scientists in California have partnered together to conduct comparative, multi-estuary farm trials of discrete Pacific oyster (Crassostrea gigas) lineages. In this thesis we investigate how the more recently imported Midori lineage performs compared to the historically used Miyagi lineage, as well as a Hybrid (Midori x Miyagi) lineage. As part of a 7-month long field study from April-November of 2024 in Morro Bay and Tomales Bay, California, we evaluated …

Asm And A Culture Of Sharing, Caring, And Fun In Education, David J. Westenberg

Biological Sciences Faculty Research & Creative Works

One doesn't always equate a professional scientific society with sharing, caring, and fun, but in this age of public distrust, public engagement with science and active student learning are ways to regain trust. ASM holds a leadership position in promoting and recognizing the value of education in the future of our profession and is there to support your educational journey. From K12 outreach and public engagement, to professional development, to presenting and publishing scholarship of teaching and learning, ASM has been at the forefront of biology education. Under the leadership of visionary directors such as Amy Chang and now Irene …

Spatial And Hydrologic Effects Of Climate Change And Urbanization On Freshwater Fish Communities In North Georgia Watersheds, Mayuko Mizutani

Master's Theses

Urbanization and climate change are altering streamflow and land cover across the southeastern United States, threatening freshwater biodiversity in rivers already burdened by impoundments and habitat loss. I investigated how changes in streamflow and land cover might affect fish community biodiversity in the Etowah River watershed of North Georgia. By combining a dataset of fish collections from 1999 through 2019 with contemporaneous land use and daily streamflow, I was able to model fish community responses to urbanization and climate-driven hydrologic changes and then forecast fish community structure under multiple CMIP6 global climate models and greenhouse gas emissions scenarios (SSP2-4.5 and …

Divergent Belowground Strategies Of Savanna Grasses Under Varying Fire Regimes, Abigail C. Schmidt

All Graduate Theses and Dissertations, Fall 2023 to Present

Savannas are unique ecosystems, where trees and grasses live together across the landscape, not quite forming full forests or open grasslands. The ability for trees and grass to coexist is largely the result of widespread disturbances, such as fire. Fire in savannas is largely thought of in how it maintains plants above ground, however, fire also plays a key role in ecosystem and plant processes belowground. First, fire can change how soil nutrients, namely phosphorus, are cycled. Phosphorus is a key nutrient that plants need to function, and plants acquire phosphorus through their roots. Frequent fire can enhance phosphorus availability, …

Understanding And Predicting Precipitation Characteristics In The United States Through Machine Learning, Numerical Modeling And Measurements, Cody Luther Ratterman

All Graduate Theses and Dissertations, Fall 2023 to Present

Precipitation is one of the most important yet uncertain variables in the climate system. It varies dramatically in terms of timing, accumulation, rate, and phase, depending on location, season, circulation patterns, and atmospheric conditions. Precipitation forecasts, especially snowfall, are essential to supporting drought mitigation and water management in the Intermountain West. Because rainfall and snowfall lead to opposite effects on snowpack, accurately partitioning rain and snow is important to estimate snowpack levels, winter recreation, mountain ecosystems and runoff. The research findings in this dissertation have advanced the understanding and prediction of precipitation and snowpack in the U.S. by addressing the …

Drought And Diet Breadth: Does Insect Specialization Influence Herbivory When Plants Are Under Stress?, Jakob Palmer

All Graduate Theses and Dissertations, Fall 2023 to Present

Climate change will alter precipitation worldwide, causing more frequent and severe drought events worldwide. Drought affects many ecological processes, including plant-herbivore interactions, which are critical to biodiversity and ecosystem health. A variety of plant characteristics can influence herbivory – such as how hairy, nutritious, or toxic a leaf is – and drought has been shown to alter many of these traits. Unique characteristics of herbivore species are also important: herbivores can either feed on a variety of plants (generalists) or a group of closely related plants (specialists). Specialists can cope with traits of the plants they eat, while generalists are …

Optimizing Urban Forestry Through Green Infrastructure: Tree Health And Water Retention In Ciudad Juarez Rain Gardens, Tomas Rogelio Lizarraga Ruiz

Open Access Theses & Dissertations

Urban green spaces (UGS) in arid regions face significant challenges due to water scarcity and extreme thermal demand. This study evaluates the efficacy of Nature Based Solutions (NBS), rain gardens and median strips, in enhancing the physiological resilience of urban trees in Ciudad Juárez, Mexico. Using a comparative framework, the research monitored a native evergreen (Dermatophyllum secundiflorum) and an introduced deciduous species (Morus sp.) across six planting treatments. Statistical analysis reveals that green infrastructure (GI) acts as a critical physiological accelerant. Trees situated within rain gardens and medians significantly outperformed those in restricted pot and sidewalk settings, maintaining higher stomatal …