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Back Matter Mar 1984

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.


Review Of Concepts In Nematode Systematics: Proceedings Of An International Symposium Held Jointly With The Association Of Applied Biologists, By A.R. Stone, H.M. Platt, L.F. Khalil And D.L. Hawksworth (Academic Press, 1983), Daniel R. Brooks Mar 1984

Review Of Concepts In Nematode Systematics: Proceedings Of An International Symposium Held Jointly With The Association Of Applied Biologists, By A.R. Stone, H.M. Platt, L.F. Khalil And D.L. Hawksworth (Academic Press, 1983), Daniel R. Brooks

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Review of Concepts in Nematode Systematics: Proceedings of an International Symposium held jointly with the Association of Applied Biologists, in Cambridge, September 2-4, 1981, by A.R. Stone, H.M. Platt, L.F. Khalil and D.L. Hawksworth (Academic Press, 1983).


Effect Of Membrane Filtration Of Antimalarial Drug Solutions On In Vitro Activity Against Plasmodium Falciparum, J. Kevin Baird, C. Lambros Jan 1984

Effect Of Membrane Filtration Of Antimalarial Drug Solutions On In Vitro Activity Against Plasmodium Falciparum, J. Kevin Baird, C. Lambros

United States Public Health Resources

Antimalarial activities ofchloroquine, mefloquine, amodiaquine, and quinine in vitro against Plasmodium falciparum were diminished as a consequence ofmembranefiltration. Filtered drug solutions gave ID50 values up to 25-fold greater than those of non-filtered (ethanol-sterilized) drug solutions. Loss ofactivity byfiltration was overcome by increasing the drug concentration prior to filtration. Water solutions filtered through Millex-GSfilter units consistently showed an absorbance maximum at 277 nm, accompanied by a lesser peak at 225 nm. Water filtrates from Nucleopore and Millex-G Vfilters showed no absorbance at 277 nm and only slight absorbance was evidentfor the Gelmanfilter unit. Activity losses were attributed to extractable contaminating …


Myxomatosis In Western Australia, D R. King, S. H. Wheeler Jan 1984

Myxomatosis In Western Australia, D R. King, S. H. Wheeler

Journal of the Department of Agriculture, Western Australia, Series 4

Since myxomatosis was introduced to Western Australia in the early 1950s rabbit plagues have ceased. However, myxomatosis has not proven to be the whole answer to the rabit problem.

Rabits continue to damage crops and pastures in many areas and resurgences of rabbit populations are reported from time to time.

Drs D.R. King and S. H. Wheeler of the Agricultural Protection Board's research section have been studying the way myxomatosis epidemics occur and spread in rabbit populations in a range of Western Australian environments. This research will provide data for planning effective control strategies intergrating the various control options available …


Dispelling Some Myths About 'Dermo', J R. Edwards Jan 1984

Dispelling Some Myths About 'Dermo', J R. Edwards

Journal of the Department of Agriculture, Western Australia, Series 4

There are a lot of misconceptions and myths about dermatophilosis, a disease which can kill young lambs, affect wool quality, make shearing difficult and make sheep susceptible to fly strike.

One misconception is perpetuated by the incorrect use of the name mycotic dermatitis, which implies that a fungus causes the disease. This is not so.

The disease is caused by the bacteria Dermatophilus congolensis, which attacks the sheep's skin and eventually forms a lesion or scab in the wool, and so is better called dermatophilosis, 'dermo' or 'lumpy wool'.

Veterinary Epidemiologist at the Albany Regional Office, J.R. Edwards, discusses …


Enteric Redmouth Disease Of Salmonids, G. L. Bullock Jan 1984

Enteric Redmouth Disease Of Salmonids, G. L. Bullock

United States Fish and Wildlife Service: Publications

Enteric redmouth disease (ERM) is a systemic bacterial infection of fishes, but is principally known for its occurrence in rainbow trout, Salmo gairdneri. The disease was first reported in the 1950's by Rucker (1966), and in recognition of that fact, the causal organism was named Yersinia ruckeri by Ewing et al. (1978). Although Wagner and Perkins (1952) described a bacterial disease that produced a red-mouth condition in rainbow trout in California and Colorado, it was caused by a different bacterium; they isolated Pseudomonas hydrophila rather than Y. ruckeri.


Survival Of Trypanosoma Cruzi In Dead Chronically Infected Mice, Lawrence C. Hinck, James L. Stevens, Rogers D. Meurer Jan 1984

Survival Of Trypanosoma Cruzi In Dead Chronically Infected Mice, Lawrence C. Hinck, James L. Stevens, Rogers D. Meurer

Journal of the Arkansas Academy of Science

No abstract provided.


Helminth Parasites Of The Endangered Houston Toad, Bufo Houstonensis Sanders, 1953 (Amphibia, Bufonidae), Robert A. Thomas, Steven A. Nadler, W. Lynn Jagers Jan 1984

Helminth Parasites Of The Endangered Houston Toad, Bufo Houstonensis Sanders, 1953 (Amphibia, Bufonidae), Robert A. Thomas, Steven A. Nadler, W. Lynn Jagers

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The Houston toad, Bufo houstonensis Sanders, has an extremely restricted range in southeastern Texas, being known historically from 6 counties with viable populations remaining in only 2, Due to its relative rarity and federally protected status as an endangered species, its parasites have received attention only once. Harwood (1932, Proc. U.S. Natl Mus. 81: 1-71) identified 2 Harris County specimens of this toad as B. terrestris and reported Cosmocercoides dukae (Oxyuridae) in both and Oswaldocruzia pipiens (Diaphanocephalidae) in 1. In the course ofecological studies on the Houston toad, additional information on its parasitic helminths has been acquired.


Alcataenia Campylacantha (Krabbe, 1869) From Pigeon Guillemots, Cepphus Columba Pallas, And Black Guillemots, Cepphus Grylle (Linnaeus), And Alcataenia Sp. Indet. (Cestoda: Dilepididae) From Kittlitz's Murrelets, Brachyramphus Brevirostris (Vigors) In Alaska, Eric P. Hoberg Jan 1984

Alcataenia Campylacantha (Krabbe, 1869) From Pigeon Guillemots, Cepphus Columba Pallas, And Black Guillemots, Cepphus Grylle (Linnaeus), And Alcataenia Sp. Indet. (Cestoda: Dilepididae) From Kittlitz's Murrelets, Brachyramphus Brevirostris (Vigors) In Alaska, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Alcataenia campylacantha (Krabbe, 1869) is redescribed and reported for the first time from pigeon guillemots, Cepphus columba Pallas, in Alaska. Specimens of this cestode were also found in black guillemots, Cepphus grylle (Linnaeus) at Point Barrow, Alaska. There were no substantial differences in morphological characters between populations of this cestode from the North Atlantic and North Pacific basins. Additionally, Alcataenia sp. indet. is reported, with a partial description, from Kittlitz's murrelets, Brachyramphus brevirostris (Vigors), in Alaska. This constitutes the first record of dilepidid cestodes from birds of the genus Brachyramphus Brandt.

French abstract:

On trouvera ici une nouvelle description d’ …


Alcataenia Longicervica Sp. N. From Murres, Uria Lomvia (Linnaeus) And Uria Aalge (Pontoppidan) In The North Pacific Basin, With Redescriptions Of Alcataenia Armillaris (Rudolphi, 1810) And Alcataenia Meinertzhageni (Baer, 1956) (Cestoda: Dilepididae), Eric P. Hoberg Jan 1984

Alcataenia Longicervica Sp. N. From Murres, Uria Lomvia (Linnaeus) And Uria Aalge (Pontoppidan) In The North Pacific Basin, With Redescriptions Of Alcataenia Armillaris (Rudolphi, 1810) And Alcataenia Meinertzhageni (Baer, 1956) (Cestoda: Dilepididae), Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Alcataenia longicervica sp. n. (Cestoda: Dilepididae) is described from murres, Uria spp., in Alaska and other localities in the Pacific basin. From Alcataenia armillaris (Rudolphi, 1810), which it most closely resembles, A. longicervica is distinguished by larger size of organs (cirrus sac, vitelline gland, and seminal receptacle), greater number of testes, and extremely long neck. In specimens of A. longicervica there are 22-27 rostellar hooks distributed in two rows. Hooks in the anterior row measure 41-49 μm in length while those in the posterior are 38-48 μm. Two species of Alcataenia, A. armillaris and A. meinertzhageni (Baer, 1956), both …


Trematode Parasites Of Marine Birds In Antarctica: The Distribution Of Gymnophallus Deliciosus (Olsson 1893), Eric P. Hoberg Jan 1984

Trematode Parasites Of Marine Birds In Antarctica: The Distribution Of Gymnophallus Deliciosus (Olsson 1893), Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

During continuing studies of avian helminths at Palmer Station, Antarctica (Hoberg 1983) trematodes were found as parasites only of charadriiform birds. Digeneans were not represented in extensive collections (including several thousand specimens of helminths) from spheniscids, procellariids, and phalacrocoracids.

The pattern of distribution of trematodes in marine birds in Antarctica is influenced by the availability of suitable intermediate hosts (mollusca) and the foraging behavior of potential final hosts. Littoral environments near Palmer are structurally simple and of low diversity due to ice scouring. The limpet, Nacella polaris, is the dominant intertidal invertebrate and one of the few molluscs that …


Postembryonic Development Of The Redwood Nematode, Rhizonema Sequoiae (Nemata: Heteroderidae), I. Cid Del Prado Vera, Armand R. Maggenti, B. F. Lownsbery Jan 1984

Postembryonic Development Of The Redwood Nematode, Rhizonema Sequoiae (Nemata: Heteroderidae), I. Cid Del Prado Vera, Armand R. Maggenti, B. F. Lownsbery

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Second-stage larvae of Rhizonema sequoiae Cid del Prado Vera et al. developed into adult females in 6 months or adult males in 3-4 months on roots of Sequoia sempervirens maintained in a growth chamber at 16 C with a 12-hour light period. Under these conditions the second-stage larvae increased in diameter, the central cells of the genital primordium increased in size, and their nuclei enlarged. Mesenchymal cells accumulated in the esophageal and tail regions. Second-stage larvae become third-stage males or females 2 months after inoculation of redwood roots. Their sex could be distinguished by the ratio of length to width …


Morphometrical Variability In Helicotylenchus Steiner, 1945. 4 : Study Of Field Populations Of H. Pseudorobustus And Related Species, Renaud Fortuner, Armand R. Maggenti, Laurel M. Whittaker Jan 1984

Morphometrical Variability In Helicotylenchus Steiner, 1945. 4 : Study Of Field Populations Of H. Pseudorobustus And Related Species, Renaud Fortuner, Armand R. Maggenti, Laurel M. Whittaker

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Multivariate analyses were made on 28 populations of Helicotylenchus pseudorobustus, eleven populations of H. dihystera, and type populations of H. microlobus, H. bradys, H. phalerus, H. egyptiensis, and H. africanus. Some morphological differences were observed among the populations of H. pseudorobustus, mostly between samples from North America and from Western Europe. The differences were most apparent in the pattern of junction of the inner lines of lateral field on tail, the position of the phasmids and of the dorsal gland opening. However, these characters vary within some of the populations studied. Most populations originally identified …


Taxonomy Of North American Fish Eimeriidae, Steve J. Upton, David W. Reduker, William L. Current, Donald W. Duszynski Jan 1984

Taxonomy Of North American Fish Eimeriidae, Steve J. Upton, David W. Reduker, William L. Current, Donald W. Duszynski

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Taxonomic descriptions, line drawings, and references are given for the 30 named and 5 unnamed species of North American fish Eimeriidae. In addition, a key was developed based on available morphologic data to distinguish between similar species. Taxa are divided into two genera: Eimeria (27 species) which are tetrasporocystic with dizoic, nonbivalved sporocysts, and Goussia,/i> (3 species) which are tetrasporocystic with dizoic, bivalved sporocysts that lack Stieda bodies and have sporocyst walls composed of two longitudinal valves.


Angularella Audubonensis Sp. N. (Dilepididae) And Other Cestodes Of Cliff Swallows In Colorado, Jeffrey D. Stamper, Gerald D. Schmidt Jan 1984

Angularella Audubonensis Sp. N. (Dilepididae) And Other Cestodes Of Cliff Swallows In Colorado, Jeffrey D. Stamper, Gerald D. Schmidt

Harold W. Manter Laboratory of Parasitology: Faculty Publications

One hundred forty-five cliff swallows, Petrochelidon pyrrhonota, were examined for cestodes in two separate surveys in Weld County, Colorado. Seven species representing four genera were found. Angularella audubonensis sp. n. is differentiated by the small size of the rostellar hooks (8.4-13.5 μm) and the medial relationship of the cirrus pouch to the osmoregulatory canals. Other species collected were Angularella beema, Anonchotaenia globata, Mayhewia ababili, Vitta magniuncinata, Vitta parvirostris and Vitta riparia. Seven new hosts and geographic distribution records were established for Colorado, and six new records were determined for North America.


A Checklist Of Parasites Of California, Oregon, And Washington Marine And Estuarine Fishes, Milton S. Love, Mike Moser Dec 1983

A Checklist Of Parasites Of California, Oregon, And Washington Marine And Estuarine Fishes, Milton S. Love, Mike Moser

Harold W. Manter Laboratory of Parasitology: Faculty Publications

This report is a summary of the published records of parasites found from the marine and estuarine fishes of California, Oregon, and Washington. Coverage has not been limited to the western United States, but rather includes parasite reports from throughout each fish's range. Included is a host-parasite list and parasite-host cross index.

We have produced this survey because we felt there was a need for a single source which would list all the parasites infecting marine and estuarine fish from California, Oregon, and Washington. Pertinent sources are scattered over a number of journals, covering many years. Workers find it time …


Identification Of Four Complementary Rna Species In Akabane Virus-Infected Cells, Asit K. Pattnaik, G. Abraham Sep 1983

Identification Of Four Complementary Rna Species In Akabane Virus-Infected Cells, Asit K. Pattnaik, G. Abraham

School of Veterinary and Biomedical Sciences: Faculty Publications

The analysis of RNA extracted from purified Akabane virus demonstrated the presence of three size classes of single-stranded RNAs with sedimentation coefficients of 31S (large, L), 26S (medium, M), and 13S (small, S). Molecular weights of these RNA species were estimated to be 2.15 x 106,1.5 X 106, and 0.48 x 106 for the L, M, and S RNAs, respectively. Hybridization analysis involving viral genomic RNA and RNA from virus-infected cells resulted in the identification of four virus-specific cRNA species in infected cells. These cRNAs were found to be nonpolyadenylated by their inability to bind …


Agricultural Experiment Station News August 1983 Aug 1983

Agricultural Experiment Station News August 1983

Agricultural Research Division: News and Annual Reports

CONTENTS:
FACULTY DEVELOPMENT LEAVES
STATION NAME CHANGE PROPOSED
FIELD LABORATORY TASK FORCE
NAME THE NEW EVENT
NATIONAL RESEARCH PRIORITIES
FACULTY DEVELOPMENT LEAVE REPORT
PROJECT REVIEWS
GOVERNOR SUPPORTS AG RESEARCH
AGRONOMY DEPARTMENT HEAD SEARCH
BUDGET REALLOCATION
GRANTS & CONTRACTS
NEW OR REVISED PROJECTS
PROJECT ACCOMPLISHMENTS
PANHANDLE STATION DIRECTOR POSITION


Biosynthesis And Degradation Of Storage Protein In Spores Of The Fungus Botryodiplodia Theobromae, Gary Petersen, Kurt Dahlberg, James L. Van Etten Aug 1983

Biosynthesis And Degradation Of Storage Protein In Spores Of The Fungus Botryodiplodia Theobromae, Gary Petersen, Kurt Dahlberg, James L. Van Etten

Department of Plant Pathology: Faculty Publications

Muiridin, a spore-specific protein of the fungus Botryodiplodia theobromae, comprises about 25% of the mature pycnidiospore protein. It has an apparent molecular weight of 16,000 to 17,000 and is rich in glutamine, asparagine, and arginink. Muiridin is synthesized in developing spores via a precursor with an apparent molecular welght of 24,000. Two other polypeptides present in young developing spores with apparent molecular weights of 18,000 and 15,000 are immunologically related to muiridin. We propose a pathway for muiridin synthesis. Muiridin is actively degraded during the germination of spores from 30-day old cultures. This degradation is independent of exogenous amino …


Rhizonema Sequoiae N. Gen. N. Sp. From Coast Redwood Sequoia Sempervirens (D. Don) Endl., I. Cid Del Prado Vera, B. F. Lownsbery, Armand R. Maggenti Jul 1983

Rhizonema Sequoiae N. Gen. N. Sp. From Coast Redwood Sequoia Sempervirens (D. Don) Endl., I. Cid Del Prado Vera, B. F. Lownsbery, Armand R. Maggenti

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Rhizonema sequoiae n. gen. n. sp. is described from the roots of Coast Redwood, Sequoia sempervirens (D. Don) Endl., growing near Lake Lagunitas, Marin County, California. Rhizonema females are annulated over their entire bodies, are wholly embedded in host tissue, and secrete an abundant amount of gel material. Mature females do not form a cyst. The vulva is located on a large posterior terminal cone, and the anus is on the dorsal vulval lip. Esophageal glands of the second-stage larvae fill more than half of the body cavity. Tails of the vermiform males are blunt, and a cloacal tubus is …


Recommendations For Care Of The Asymptomatic Patient, James D. Bridges, Thomas Killip, N. Kevin Krane, David B. Macdougall, Carlos F. Petrozzi, Michael E. Somand, Susan Steigerwalt Jun 1983

Recommendations For Care Of The Asymptomatic Patient, James D. Bridges, Thomas Killip, N. Kevin Krane, David B. Macdougall, Carlos F. Petrozzi, Michael E. Somand, Susan Steigerwalt

Henry Ford Hospital Medical Journal

We present a set of reasonable guidelines for the care of healthy, asymptomatic individuals based upon recommendations prepared by an Internal Medicine review committee of Henry Ford Hospital. There recommendations have four goals: to prevent disease, to detect disease in an asymptomatic and potentially curable state, to enhance the patient's quality of life, and to help physicians teach patients good health habits. Recommendations are made for infectious diseases, cancer, metabolic diseases, neurosensory conditions like visual and hearing loss, and general health habits. Some recommendations are at variance with those of well recognized authorities and should be viewed only as a …


Aspects Of The Biology Of The Red Drum, Sciaenops Ocellatus, In Mississippi, Robin M. Overstreet Jun 1983

Aspects Of The Biology Of The Red Drum, Sciaenops Ocellatus, In Mississippi, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Several hundred specimens of the red drum from Mississippi were critically assessed. Regression equations for standard-length (SL) versus total-length differed between males and females and between small and large members of the same sex. Asingle regression line represented the weight-SL relationship for males with females. For condition coefficients to be helpful, fish had to be grouped at least by sex, season, and length or stage of maturity. By 12 months of age, most fish were about 30 to 32 cm SL and their distribution ranged throughout Mississippi Sound rather than being restricted to inshore bayou and marsh habitats like younger …


Aspects Of The Biology Of The Spotted Seatrout, Cynoscion Nebulosus, In Mississippi, Robin M. Overstreet Jun 1983

Aspects Of The Biology Of The Spotted Seatrout, Cynoscion Nebulosus, In Mississippi, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

About 3,000 specimens of the spotted seatrout from Mississippi Sound and adjacent water grouped by males and females had a nearly identical standard Iength (SL) versus total length (TL) relationship, although the equation for males in winter differed from that for those in other seasons. When investigating the SL-weight relationship, some differences occurred both among seasons and between sexes. Therefore, condition coefficients (K) were calculated to compare male and female groups according to their length and state of maturation on a seasonal basis. The hepatosomatic index (HSI) tended to increase with fish length, with relatively high values occurring in winter …


Organization Of Sporulated Oocysts Of Eimeria Funduli In The Gulf Killifish, Fundulus Grandis, William E. Hawkins, John W. Fournie, Robin M. Overstreet Jun 1983

Organization Of Sporulated Oocysts Of Eimeria Funduli In The Gulf Killifish, Fundulus Grandis, William E. Hawkins, John W. Fournie, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Oocysts of Eimeria funduli were studied by transmission electron microscopy in naturally-infected livers of the Gulf killifish, Fundulus grandis. Tissues were cryo-processed because membranous structures in the oocyst appear to hinder routine fixation and embedment. The oocyst wall (about 25 nm thick) was adjacent to the host cell and consisted of an outer membrane that limited the host cell cytoplasm and an inner membrane separated from the outer membrane by a narrow space. In some specimens, dense material was applied to the inner face of the inner membrane. Individual sporocysts were surrounded by a membranous "veil" (about 25 nm …


Natural Killer Activity In Gardner's Syndrome, Ann Marie Stembridge May 1983

Natural Killer Activity In Gardner's Syndrome, Ann Marie Stembridge

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Gardner's syndrome is an autosomal dominant disease presenting multiple colonic polyps with a predisposition for malignant change. In addition to colonic polyp formation by early adolescence, extracolonic lesions appear often prior to polyp formation. One theoretical mechanism for the origin of polyps and malignancies in Gardner's syndrome is a genetic defect in the natural killer cell activity of patients with this disease. Natural killer cells are a subpopulation of lymphocytes that spontaneously lyse tumor cells and virally transformed cells. A study was undertaken to determine the natural killer activity of patients with Gardner's syndrome.

A technique termed chromium release was …


Evaluation Of The Status Of Texanocotyle Pogoniae And Laterocotyle Padreinsulae (Trematoda: Aspidogastridae), Sherman S. Hendrix, Robin M. Overstreet Apr 1983

Evaluation Of The Status Of Texanocotyle Pogoniae And Laterocotyle Padreinsulae (Trematoda: Aspidogastridae), Sherman S. Hendrix, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Simpson and McGraw (1979, Southwest. Nat. 24: 557-562) erected two genera for two new species of aspidogastrid trematodes infecting the black drum, Pogonias cromis (Linnaeus), along the Texan Gulf of Mexico coast. Examination of holotypes and paratypes of each reveals that the two species have been described previously and that the genera are invalid.


Review Of The Grizzlies Of Mount Mckinley By Adolph Muire, Robert L. Rausch Apr 1983

Review Of The Grizzlies Of Mount Mckinley By Adolph Muire, Robert L. Rausch

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Review of The Grizzlies of Mount McKinley by Adolph Murie. U.S. Department of the Interior, National Park Service, Scientific Monograph Series No. 14. U.S. Government Printing Office, Washington, D.C., 1981. xvi, 251 p., ill.


The Role Of Splenectomy In Endocarditis, Donald J. Magilligan Jr., Edward L. Quinn Mar 1983

The Role Of Splenectomy In Endocarditis, Donald J. Magilligan Jr., Edward L. Quinn

Henry Ford Hospital Medical Journal

Five patients with endocarditis, persistent sepsis, and positive liver-spleen scans underwent splenectomy. Three had splenectomy performed concomitantly with cardiac valve replacement, one after valve replacement and one as an isolated procedure. Four of five spleens contained abscesses, and bacterial cultures of two were positive. Histologic study of one spleen revealed splenitis. All patients improved after splenectomy, and all are well two to twenty months postoperatively. An aggressive approach to splenic abscess in endocarditis may lead to reduced mortality from bacterial endocarditis and infected prosthetic valves.


Agricultural Experiment Station News March 1983 Mar 1983

Agricultural Experiment Station News March 1983

Agricultural Research Division: News and Annual Reports

CONTENTS:
AES ADVISORY COUNCIL
FACULTY SENATE COMMITTEES
ASSOCIATE DIRECTOR POSITION
NEWSWORTHY PROJECTS
NEW PROJECTS
GRANTS AND CONTRACTS
BUDGET MEETINGS SCHEDULED FOR APRIL
SCIENTIFIC EQUIPMENT INVENTORY


Two Transcription Products Of The Vesicular Stomatitis Virus Genome May Control L-Cell Protein Synthesis, David D. Dunigan, Jean M. Lucas-Lenard Feb 1983

Two Transcription Products Of The Vesicular Stomatitis Virus Genome May Control L-Cell Protein Synthesis, David D. Dunigan, Jean M. Lucas-Lenard

Nebraska Center for Virology: Faculty Publications

When mouse L-cells are infected with vesicular stomatitis virus, there is a decrease in the rate of protein synthesis ranging from 20 to 85% of that in mock-infected cells. Vesicular stomatitis virus, irradiated with increasing doses of UV light, eventually loses this capacity to inhibit protein synthesis. The UV inactivation curve was biphasic, suggesting that transcription of two regions of the viral genome is necessary for the virus to become inactivated in this capacity. The first transcription product corresponded to about 373 nucleotides, and the second corresponded to about 42 nucleotides. Inhibition of transcription of the larger product by irradiating …