Digital Commons Network^™

Soil Nutrients And Composting (Lesson 3), Mara Johnson, Jiyul Chang, Madhav P. Nepal

iLEARN Teaching Resources

In this lesson, students investigate how nutrient cycling contributes to soil health and agricultural sustainability. Building upon previous lessons on the Three Sisters planting system and soil health analysis, students explore composting as a strategy for restoring nutrients in soils. Students learn the roles of carbon-rich "browns" and nitrogen-rich "greens" in decomposition and construct miniature composting systems using locally available organic materials. Through observation, data collection, and long-term monitoring, students analyze how microorganisms recycle nutrients and convert organic matter into fertile soil amendments. Students connect composting to traditional ecological knowledge, food sovereignty, environmental stewardship, and sustainable agriculture while evaluating how …

Soil Health Analysis (Lesson 2), Mara Johnson, Madhav P. Nepal, Jiyul Chang

iLEARN Teaching Resources

In this lesson, students will build on the previous lesson (reading and analyzing the Three Sisters chapter from Braiding Sweetgrass) by experimenting on soil in their schoolyard. Students will collect soil samples from multiple locations around their school grounds and evaluate soil texture, structure, infiltration, color, organic matter, and pH. Students Through field observations and laboratory analysis, students examine how soil characteristics influence plant growth and ecosystem health. Students connect modern soil science with Indigenous agricultural knowledge, particularly the Three Sisters planting system described in Braiding Sweetgrass by Robin Wall Kimmerer. By exploring how healthy soil supports sustainable agriculture, …

Rape Pregnancies And Consequent Ptsd Resulting From The Overturn Of Roe V. Wade, Emma Lindenfelser, Yulia Garaeva, Nenette Nti-Agyemang, Ellen Davis, Anna Kabwa, Alexandra M Calaman

Binghamton University Undergraduate Journal

Prior to the 1973 Roe v. Wade ruling, access to safe legal abortions was limited and often restricted along racial, economic, and geographic lines. Nearly fifty years later, women’s health policy evolved again following the 2022 Dobbs v. Jackson Women’s Health Organization decision overturning Roe v. Wade. This court ruling decimated federal protections of abortion. This paper presents the research that the 2022 Dobbs judicial decision may contribute to and exacerbate rape-related PTSD on 1 out of 20 American who are unable to access a safe abortion after a rape-related pregnancy. Pregnant women living in conservative states that have outlawed …

Uncovering Dkk1 As A Therapeutically Relevant Target In Aggressive Er+ Breast Cancer Using A Novel Antiestrogen, Kristen Young

Dissertations

Over 70 percent of breast cancers are estrogen receptor-positive (ERα+), meaning that the hormone estrogen drives tumor growth. Although first-line targeted therapies that directly block ERα from hormone-dependent pathologies are initially effective, almost half of patients ultimately progress. These patients show high mutational rates to the ESR1 gene that encodes for ERα. A hotspot missense tyrosine to serine mutation at position 537 (Y537S) initiates hormone-independent, allele-specific transcriptional programs that increase metastasis. While next-generation ERα-targeted therapies show promise, benefits are often limited compared to standard-of-care. Understanding the mechanisms of action used by the Y537S ESR1 breast cancer cells to evade therapeutic …

Discovery Of Bmi-Associated Gut Microbiome Signatures In The Awi-Gen 2 Cohort, Meriem Yagoubi

Theses and Dissertations

Obesity is increasing across sub-Saharan Africa amid rapid dietary, environmental, and urbanization transitions, yet the gut microbiome features associated with adiposity in African populations remain under-characterized. This study investigated whether species-level gut microbiome composition is associated with body mass index (BMI) in the AWI-Gen 2 cohort, and whether BMI-associated microbial signals remain detectable after accounting for the dominant geographic structure of the microbiome. Gut microbiome community structure and diversity were characterized across 1,665 participants, and differential abundance analysis was used to identify taxa associated with BMI after controlling for study site. Machine learning models were then trained to assess how …

Disease-Causing Mfn2 Mutants Impair Mitochondrial Fission Dynamics By Distinct Drp1 Dysregulation, Daniel Lagos, Pamela R. De Santiago, Nicolás Pérez-Bravo, Benjamín Cartes-Saavedra, Josefa Vial-Brizzi, Diego Troncoso-Chandía, Oliver Podmanicky, Rita Horvath, Verónica Eisner

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Mitochondria undergo fusion and fission. While DRP1 regulates fission, fusion is controlled by OPA1, MFN1, and MFN2. The balance between these processes and the crosstalk between machineries remains poorly understood. MFN2 mutations cause Charcot-Marie-Tooth disease type 2 A (CMT2A), affecting mitochondrial fusion and morphology. However, their role in fission is unclear. Using skin fibroblasts from CMT2A patients (L248H and M376V MFN2 mutations) and wild-type mouse embryonic fibroblasts expressing these variants, we studied how MFN2 mutations impact mitochondrial dynamics beyond fusion. We analyzed mitochondrial morphology and dynamics by live-cell confocal microscopy and tested fusion/fission protein levels, oxygen consumption rate (OCR), extracellular …

Current Status Of Anthelmintic Resistance In Meat Goats: A Comparative Efficacy Study Of Albendazole And Fenbendazole In Maha Sarakham, Thailand, Minta Pipatsakulpak, Usanisa Boonum, Kotchakorn Roongruang, Benjawan Sae-Chue, Sukanya Leethongdee, Songsak Chumpawadee, Nattaya Watwiengkam, Pongphol Pongthaisong

The Thai Journal of Veterinary Medicine

Anthelmintic resistance in gastrointestinal nematodes threatens sustainable goat production globally. While resistance is well-documented in many regions, data from Thailand remain limited. This study determined the prevalence of gastrointestinal nematodes and assessed the efficacy of albendazole and fenbendazole in meat goats in Maha Sarakham province, northeastern Thailand. A two-stage cross-sectional study was conducted on 10 meat goat farms between August 2021 and March 2022. In Stage 1, fecal samples from 150 goats were examined using simple flotation and sedimentation techniques to identify parasite morphology. In Stage 2, the McMaster technique was employed to quantify fecal egg counts (FEC). Twenty-six goats …

The Relationship Between The Environment And Pollution With Surgical Outcomes And Disparities, Wendelyn Marie Oslock

ETDs from 2020-2029

Air pollution exposure has been linked to many surgically managed diseases and adverse health events that occur in the postoperative period. Despite this, the impact of air pollution on postoperative recovery is poorly understood. This knowledge gap may be one of the underlying mechanisms for persistent disparities in surgical outcomes. Previous studies have found racial and economic disparities in air pollution exposure. These same communities have been shown to experience worse surgical outcomes. The goal of this thesis is to explore if exposure to air pollution impacts surgical outcomes and determine if disparities in socioeconomic factors impact this relationship. The …

Unh Extension Pollinator Garden Certification Application, Shyloh Favreau

UNH Cooperative Extension

When you certify your garden or landscape through The UNH Extension Pollinator Garden Certification Program, you become part of a growing community committed to creating meaningful habitat for pollinators through sustainable, science-based practices. Grounded in research, education, and shared learning, the program supports gardeners of all experience levels in contributing to the health and diversity of native pollinators. From plant selection to pollinator-friendly management practices, this application will guide you in planning, refining, and developing your garden into a safe, resilient habitat for native bees and other pollinating insects.

UNH Extension staff and Master Gardener volunteers are here to …

Growing Pains: The Loss Of Plasticity To Extreme Anoxia In Developing Embryos Of Austrofundulus Limnaeus, Patrick Ryan Clouser

Dissertations and Theses

Oxygen plays a pivotal role for most animal life on Earth, so much so that even short exposures to no oxygen, anoxia, can have severe effects on the animal's wellbeing. Conversely, aerobic recovery after anoxic insult can be just as detrimental. Some animals are the exception to this rule and demonstrate survival through anoxia and recovery. There has been a great deal of research around anoxia tolerant animals, but what remains unclear are the genetic underpinnings that determine the anoxia tolerant phenotype. RNA sequencing allows for the quantification of RNA transcripts within a sample, which can indicate if a gene …

Targeting Inflammatory And Growth Signaling Pathways In Breast Cancer Through Diet, Microbiome, And Metabolite Interactions, Brittany Lorraine Witt

ETDs from 2020-2029

Breast cancer (BC) accounts for 1 in 3 (or 30%) of all new female cancers each year and is the most common malignant cancer in women in the United States. Since the 1990s, there has been a 44% decrease in BC, but there is still a significant gap between certain groups in terms of mortality rates. Black women have a higher mortality rate and risk for triple-negative breast cancer (TNBC). This may be due to social (inadequate access to health care facilities, insurance, or completion of therapy) and biological (genetic mutations, tumor characteristics, or comorbidity) factors between races and other …

Limitations And Alternative Applications Of Carbohydrate Fatty Acid Esters As Food Antimicrobials: A Review, Valeria Rodríguez Monge, Namhyeon Park

Nutrition, Dietetics, and Food Science Student Research

Carbohydrate fatty acid esters (CFAs) are nontoxic food additives with reported antimicrobial activity and growing interest as a potential safer alternative to conventional preservatives. However, their translation into real food systems remains limited. This review examined the main factors that restrict the antimicrobial performance of CFAs in foods and evaluated emerging alternative applications, particularly edible coatings, antibiofilm strategies, and synergistic combinations with other cleaning agents or processing techniques. Overall, the available evidence indicates that the antimicrobial efficacy of CFAs is often reduced in real food matrices compared with in vitro conditions. This loss of activity has been mainly associated with …

National Agricultural Library (Nal) Search., Leah Everitt, Sonya Lemke

Publications

SEARCH is the USDA National Agricultural Library (NAL)'s main discovery platform that provides integrated access to the NAL Digital Collections, Special Collections, PubAg and AGRICOLA. NAL SEARCH is a valuable tool for health science librarians, students, and professionals seeking veterinary science, nutrition, or animal experiment alternatives. This article aims to give users a comprehensive overview of this resource.

Wrack Lines Spring-Summer 2026 Volume Number 1, Margaret Cozens, Johann Heupel, Owen Placido, Paul Salopek, Judy Benson

Wrack Lines

“Building community around the places we love,” is the theme of the Spring-Summer 2026 issue of Wrack Lines magazine. Learn about the work of the Six Lakes Park coalition in Hamden, Riverfront Recapture in Hartford, MyCoast in southeastern Connecticut and the statewide land conservation conference. Additional stories tell about the artistry and mission of photographer-videographer Tomas Koeck, and National Geographic explorer Paul Salopek, who is traveling the world on foot.

Loss Of Mct1 Mediated Lactate Uptake Causes Delayed Endplate Maturation And Intervertebral Disc Degeneration, Maria Tsingas, Konstantinos Tsingas, Mei Smyers, Wujuan Zhang, Aaron R. Goldman, Eulisa Lawrence, John A. Collins, Makarand V. Risbud

Department of Orthopaedic Surgery Faculty Papers

During skeletal growth, it is thought that the lactate secreted by the glycolytic nucleus pulposus (NP) cells exits the intervertebral disc into circulation via endplates. Our current studies challenge this long-held notion. Mice with early postnatal, endplate, and annulus fibrosus-specific deletion of lactate importer, MCT1, exhibited disc degeneration characterized by NP cell loss and pronounced endplate structural changes. Using metabolic and transcriptomic approaches, we demonstrate that MCT1 loss inhibits endplate chondrocyte differentiation and that lactate serves both as a crucial TCA metabolite and promotes protein and histone lactylation and gene expression. These findings suggest that during skeletal growth, NP-derived lactate …

Vitamin D–Amp Axis In Host Defense Against Fungal Infections, Nuraly S. Akimbekov, Ilya Digel, Svetlana K. Sakhanova, Kuanysh Tastambek, Dinara K. Sherelkhan, Mohammed S. Razzaque

School of Medicine Publications

Vitamin D–mediated regulation of antimicrobial peptides (AMPs) is an important focus in innate immunology and is aimed at elucidating the role of vitamin D in enhancing antimicrobial defense. AMPs are short protein chains that serve as a first line of defense against invading pathogens, including fungi, bacteria and viruses. Unlike conventional antibiotics, AMPs are produced endogenously and are less likely to induce antimicrobial resistance, making them promising candidates for treating infections caused by drug-resistant pathogens. Studies indicate that optimal vitamin D levels are essential for activating antimicrobial pathways and regulating AMPs that target multiple fungal pathogens. This article summarizes recent …

Napier Grass (Pennisetum Purpureum) Meal Modulates Growth Efficiency, Gut Morphology, And Systemic Health In Broiler Chickens, Eric Lim Teik Chung, Yee Lyn Ong, Nazri Nayan, Muhamad Faris Ab Aziz, Faez Firdaus Abdullah Jesse, Faizal Andri, Arissara Sopawong

The Thai Journal of Veterinary Medicine

Grass and leaf meals, which include vital phytocompounds, have the potential to be a natural and safe alternative to antibiotics in the poultry industry. Therefore, this study aims to assess Pennisetum purpureum leaf meal and its phytocompounds on the health performances of colored-broilers. A total of 216 unsexed Sasso chicks were assigned to six diet groups. The negative control (T1) received a commercial basal diet without antibiotics, while the positive control (T2) received the same diet with oxytetracycline (100 mg/kg). Groups T3 to T6 received no antibiotics and included P. purpureum meal at 1.25, 2.50, 3.75, or 5.00 grams per …

Severity Of Deficit In Skeletal Muscle Lipid Metabolism Invokes Unique Adaptive Responses In Dietary Lipid Intake And Absorption, Victoria Datta

Masters Theses

Skeletal muscle plays a central role in whole-body lipid metabolism through mitochondrial and peroxisomal fatty acid oxidation (FAO). When skeletal muscle lipid metabolism is impaired, whole-body adaptations occur to maintain metabolic homeostasis. We hypothesized that limiting skeletal muscle lipid metabolism through mitochondria and/or peroxisomes would trigger adaptive responses to reduce dietary lipid intake and/or absorption with the most robust changes coinciding with deficit severity. Mice were generated with skeletal muscle-specific deletion of 1) carnitine palmitoyltransferase 1b (Cpt1bM-/-) to limit mitochondrial FAO, 2) peroxin 5 (Pex5M-/-) to impair peroxisomal FAO, and 3) both Cpt1b and Pex5 (DKO). Results were compared to …

Effects Of L-Baiba Supplementation With And Without Grains Of Paradise On Changes In Resting Metabolic Rate, Body Composition, And Cardiometabolic Risk Factors, Leah E. Allen, Paige J. Sutton, Alex Schrautemeier, Kevin Holley, Connor J. Gaige, Joesi M. Krieger, Anthony M. Hagele, Karenina Antequera Gutierrez, Petey Mumford, Chad Kerksick

Faculty Symposium

To evaluate the impact of 56 days of supplementing with L-BAIBA or L-BAIBA + GOP (BGOP) on resting metabolic rate, body composition, perceptual indicators of mood and affect, and cardiometabolic markers in overweight and obese men and women.

METHODS: Healthy men and women (43.2±11.4 years, 169.4±7.6 cm, 90.3±15.6 kg, 31.4±4.4 kg∙m-2) completed a weekly exercise program and followed a calorierestrictive diet and were randomly assigned in a double-blind and blocked manner according to sex and DXA lean mass to consume daily either a placebo (PLA) (n=12 [11F, 1M]), 500 mg L-BAIBA (L-BAIBA: MitoBurn™, NNB Nutrition) (n=13 [9F, 4M]), or …

First Course Portfolio For Plpt 803 Fundamentals Of Scientific Discovery, Hernan Garcia-Ruiz

UNL Faculty Course Portfolios

PLPT 803 Fundamentals of Scientific discovery is a new curse in the Department of Plant Pathology at the University of Nebraska-Lincoln. I designed and developed this course from the ground up. Initially, it was offered as a special topic (PLPT 892-014) for four years. PLPT 803 was approved by the College of Agricultural Sciences and Natural Resources curriculum committee in September of 2025. PLPT 803 is unique within the University of Nebraska system and will be offered for the first time in the fall of 2027. The course is designed for students to learn fundamental scientific skills such as scrutinize, …

Nmda Receptor Subunit Nmr-2 Regulates Pathogen-Induced Immune Responses Via The Nervous System In C. Elegans, Benson Otarigho, Jonathan Lalsiamthara, Alejandro Aballay

Faculty, Staff and Student Publications

Neural control of innate immunity must balance restraint of basal immune activity with rapid activation upon pathogen encounter. Glutamate, the primary excitatory neurotransmitter in the nervous system, has been implicated in several neurological disorders associated with inflammation, suggesting a potential link to immune regulation. However, how glutamatergic signaling contributes to immune balance remains unknown. Here, we demonstrated that the NMDA-type ionotropic glutamate receptor subunit NMR-2, a component of the NMDA receptor complex, acts in the

Life-Stage Specific Predatory Efficiency Of 2 Generalist Predators Of Bemisia Tabaci (Hemiptera: Aleyrodidae), Itohan Aigbedion-Atalor, Abdelmutalab G. Azrag, Alvin M. Simmons, Jason M. Schmidt

All Peer-Reviewed Publications

Bemisia tabaci (Gennadius) is an economically damaging invasive pest to global vegetable production. Current management strategies rely heavily on insecticides, but increasing levels of resistance raise sustainability concerns. Therefore, strengthening integrated pest management (IPM) programs requires enhancing biocontrol through improved predator-pest interactions. Despite the well-established relevance of functional response modulation by multiple environmental factors, limited research has explored how plant traits and prey life stages interact to influence the efficiency of generalist predators in vegetable systems. To address this gap, we evaluated the functional responses of 2 adult generalist predators, Hippodamia convergens (Guérin-Méneville) and Geocoris punctipes (Say), against 3 nymphal …

Diabetes Mellitus Exacerbates Covid-19 Severity And Prolongs Recovery: A Clinical Study From Southern Iraq, Hussein Ali Hussein Al-Hchaimi, Mohammad Ali Hassan Jassim, Mustafa Abbass, Shahab Abdulla, Ralela Makline

AUIQ Complementary Biological System

Diabetes mellitus (DM) constitutes one of the most consequential comorbidities shaping the clinical trajectory of Coronavirus Disease 2019 (COVID-19), operating through intersecting mechanisms of chronic inflammation, endothelial injury, and immunosuppression that collectively amplify viral pathogenicity. This study investigated the impact of diabetes type on COVID-19 symptom severity, hospitalization duration, and recovery time among patients in Nasiriyah City, southern Iraq — a region substantially underrepresented in the global DM–COVID-19 literature. A descriptive cross-sectional study was conducted across healthcare facilities in Nasiriyah City from 2023 to 2024. A total of 150 hospitalized adult patients carrying confirmed diagnoses of both COVID-19 and type …

[2026 Winner] Seed Sovereignty Through The Lens Of Decolonization, Lily A. Marx

Ethnic Studies Research Paper Award

This paper explores the movement of seed sovereignty, a contemporary movement stemming from the history of theft, appropriation, and forced assimilation endured by indigenous peoples. This movement recognizes that consumers alone cannot mend the damage being done to our food systems, but instead encourages communities to take political action by saving seeds and rebuilding connections with the land.

City Farm Slo: A Case Study Of Nonprofit Regenerative Agriculture, Carver Tunnell

Master's Theses

The focus of this thesis is to create a case study on City Farm SLO, a nonprofit based in San Luis Obispo, California, that has engaged in education and regenerative agriculture on City owned land since 2013. This case study is intended for use in undergraduate agribusiness and natural resource management courses, to encourage thoughtful discussion surrounding nonprofit and regenerative agricultural systems. The case presents the nonprofit at a time of relative success, having recently secured a lease renewal, extending stewardship 40 years into the future. However, the reliance on grants and donations threatens the security of the operation going …

Exploring Regenerative Vegetable Systems On The Central Coast Of California, Una S. O'Connell

Master's Theses

As climate change and current agricultural practices place pressure on the long term sustainability and resilience of food production systems, there is growing interest in whether existing agricultural systems can adapt to maintain productivity while improving environmental outcomes.

This study evaluated the effects of regenerative versus standard organic vegetable production systems on yield, insect communities, and weed suppression across three field trials conducted on California's Central Coast. In addition, I collected baseline soil health data for all trials. Trials 1 and 2 were carried out at the Cal Poly San Luis Obispo Organic Farm using cabbage and broccoli as cash …

The Effects Of Maceration And Enzymes On The Chemical Characteristics Of Hard Apple Cider, Manou De Pelsmaeker

Master's Theses

The purpose of this study was to analyze the effects of maceration and pectinase enzymes on the base chemical, polyphenolic, and volatile characteristics of cider. The apples (Fuji) were milled and macerated for 0, 4, 12, 24, or 36 hours, both with and without an enzymatic pectinase addition. While base chemical characteristics such as sugar content and ABV were unaffected, the acidity of cider was influenced maceration and enzymes. Extended maceration time resulted in lower concentrations of malic acid, and enzymes resulted in a lower pH compared to the control. Polyphenols were extracted during maceration time, resulting in higher concentrations …

Movement And Space Use Of Weaned Northern Elephant Seal (Mirounga Angustirostris) Pups During Their First At-Sea Foraging Migration, Katie Saenger

Master's Theses

The northern elephant seal (Mirounga angustirostris) is a marine mammal known for engaging in long foraging migrations at sea. Adult male northern elephant seals follow pathways along the western coast of North America towards Alaska and adult female northern elephant seals follow pathways to open ocean in the North Pacific. However, there is little information on weaned northern elephant seal pup foraging behavior during their first foraging migration. This lack of knowledge is significant because northern elephant seals have a mortality rate of >50% in the first year. This project aimed to better understand the at-sea migratory movement …

Sustainable Management Of Soilborne Pathogens In Strawberry Production Through Host Resistance And Sanitation Practices, Maria G. Alvarez Arredondo

Master's Theses

Strawberry production in California is significantly impacted by soilborne pathogens that reduce plant productivity and increase management costs. This research addressed management of these pathogens through two independent approaches: evaluation of host resistance in strawberry cultivars and assessment of sanitation practices for reducing pathogen movement between fields.

Macrophomina root rot, caused by Macrophomina phaseolina, was evaluated over two growing seasons (2024–2025 and 2025–2026) using field trials at California Polytechnic State University, San Luis Obispo. In Year 1, disease incidence varied widely among genotypes, with mortality ranging from 1.3% to 88.8% and an average mortality of 26.4%. Area under the …

Land-Based Learning As A Catalyst For Climate-Resilient And Sustainable Food Systems, Bashir Adelodun, Tammara Soma, Emmanuel Sulle

Arusha Climate and Environmental Research Centre

Climate change increasingly threatens agricultural productivity, food security, and rural livelihoods, with significant impacts in regions experiencing environmental and socio-economic vulnerabilities. While technological innovations are central to advancing climate-resilient agriculture, locally embedded knowledge systems are equally critical for enabling adaptive and sustainable food systems. This study examines how land-based learning (LBL) contributes to climate resilience through intergenerational knowledge transfer and context-specific adaptation practices. The study employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, with a systematic literature search conducted across major scientific databases, i.e., Scopus and Web of Science using predefined inclusion and exclusion criteria. Eligible …