Digital Commons Network^™

A Hybrid Response Surface Methodology And Machine Learning Framework For Quantifying Effects Of Physicochemical Parameters On Pfas Distribution, Harsh V. Patel, Jazmin Green, Hyoshin Park, Stephanie Luster-Teasley Pass, Renzun Zhao

Engineering Management & Systems Engineering Faculty Publications

Predicting PFAS adsorption across diverse adsorbents and environmental matrices remains challenging because adsorbent physicochemical properties, PFAS molecular descriptors, and operational conditions simultaneously influence adsorption. This study develops and evaluates a unified hybrid modeling framework that integrates Response Surface Model (RSM) with machine-learning algorithms to quantify how six key variables, surface area, Log K_ow, pH_pzc, pK_a, log dose, and log-initial concentration, affect PFAS distribution coefficients (Log K_d). A data set of more than 1000 adsorption observations spanning 15 PFAS compounds, multiple adsorbent types, and a broad operational range was compiled and preprocessed using …

Evaluating Benthic Macroinvertebrate Communities In Streamside Management Zones In Private, Working Forests, Haley Vaglienti

College of Graduate Studies: Theses & Dissertations

Forestry operations can alter riparian vegetation and increase sediment and nutrient inputs to streams, affecting water quality and aquatic biota. Forestry best management practices (BMPs) including streamside management zones (SMZs) are designed to mitigate those effects by reducing sediment delivery and moderating temperature, flow, and nutrient regimes. We assessed ecological integrity at 24 intermittent stream sites with SMZs in private, working forests across the Piedmont and Southeastern plains of Georgia. At each site, we conducted physical habitat evaluations and characterized benthic macroinvertebrate assemblages. Sites represented a gradient of habitat conditions, SMZ widths, and pine stand ages, allowing for comparisons of …

Metabolic Syndrome Beyond Diagnostic Criteria: Population-Scale Integrative Metabolomics Characterization, Marwa Talal

Theses and Dissertations

Background: Metabolic syndrome (MetS) is a complex cluster of interrelated metabolic abnormalities associated with elevated cardiometabolic risk. While diagnosis is based on well-established five clinical criteria, these may overlook early or atypical metabolic alterations. Large-scale metabolomic profiling offers an opportunity to identify biochemical signatures of MetS beyond diagnostic bias and to evaluate their relative importance across different presentations of the syndrome.

Methods: Data from 117,147 UK Biobank participants were analyzed in a cross-sectional design. High-throughput NMR quantified 75 circulating metabolites, for. Univariate analyses, MetS subtype stratification, and elastic net models with SHAP interpretation were applied to assess feature …

Sleep Problems In Children With Adhd: Associations With Internalizing Symptoms And Physical Activity, Xiao Liang, Mengping Zhao, Li Su, Justin A. Haegele, Richard H. Xu, Jiayue Li, Jinxian Guo, Choi-Yeung Tse, Shirley X. Li, David H. K. Shum

Human Movement Studies & Special Education Faculty Publications

Children with attention deficit hyperactivity disorder (ADHD) experience high rates of sleep problems and are at increased risk for developing internalizing problems. This study aimed to examine the association of sleep problems and physical activity with internalizing symptoms in children with ADHD. This cross-sectional study included 188 children with ADHD (M age = 8.60 ± 1.38, 78.7% boys). Self-reported questionnaires were used to assess sleep problems (Pittsburgh Sleep Quality Index [PSQI]) and internalizing symptoms (Depression Anxiety Stress Scale 21 [DASS 21]). The presence of sleep problems was defined as a PSQI score > 5. Physical activity was recorded by an ActiGraph …

Associations Between Accelerometer-Measured Physical Activity And Sleep Duration And Health Indicators In Children And Adolescents With Attention-Deficit Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Xiao Liang, Hui Qiu, Justin A. Haegele, Xiao Li, Minghui Li, Jiayue Li, Shirley Xin Li

Human Movement Studies & Special Education Faculty Publications

Objective

This systematic review and meta-analysis synthesized available studies to explore relationships between accelerometer-measured physical activity (PA) levels or sleep duration and health-related outcomes in children and adolescents with attention-deficit hyperactivity disorder (ADHD).

Methods

Following the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines, the six databases APA PsychInfo, CINAHL Ultimate, Embase, MEDLINE, SPORTDiscus with Full Text and Web of Science were searched from inception through July 2024. The correlation coefficient (r) was employed to determine the effect size in the meta-analysis. A random-effects model was utilised to estimate the potentially heterogeneously distributed effect sizes with a 95 % …

Felt Ambivalence Weakens The Attitude-Intention Pathway For Regular Leisure-Time Physical Activity In Chinese Adolescents: A Three-Wavee Prospective Study, Yaogang Han, Yubing Wang, Pan Li, Guohua Zheng

Human Movement Studies & Special Education Faculty Publications

Background: Favorable attitudes toward regular leisure-time physical activity may not always translate into intention if adolescents feel ambivalent about the behavior. This study tested whether felt ambivalence weakens the prospective attitude–intention association and the indirect effect of attitude on later behavior through intention. Methods: Chinese adolescents (N = 1714; Grades 7–12; mean age = 15.0 years) completed a three-wave survey at approximately two-week intervals. Wave 1 assessed attitudes toward regular leisure-time moderate-to-vigorous physical activity, felt ambivalence, and physical activity habit; Wave 2 assessed intention; and Wave 3 assessed leisure-time physical activity. Moderated mediation was tested in a structural equation model …

From Intention To Enactment: Action Planning And Habit Automaticity Distinguish Successful From Unsuccessful Intenders To Engage In Regular Leisure-Time Moderate-To-Vigorous Physical Activity, Yaogang Han, Yubing Wang, Pan Li, Binn Zhang

Human Movement Studies & Special Education Faculty Publications

University students often intend to exercise regularly but fail to translate intention into action. The present study tested which post-intentional processes distinguish successful from unsuccessful intenders in self-reported regular leisure-time moderate-to-vigorous physical activity (MVPA) enactment. Chinese undergraduates from 10 universities completed a three-wave survey administered at roughly two-week intervals. Habit automaticity was assessed at Wave 1, intention together with action planning and coping planning at Wave 2, and self-reported regular-exercise status at Wave 3. Because the dependent variable was assessed using a single stage-based self-report item, the findings should be interpreted as explaining self-reported regular-exercise status rather than objectively measured …

The Relationship Between Physical Activity, Sleep, And Hallucinations In Adults With Charles Bonnet Syndrome, Jarrod Hollis, Rohit Narayan, Eldre W. Beukes, Rosie Lindsay, Aliyah Bharwani, Umair Mughal, Ikra Yaqoob, Justin A. Haegele, Scott Muriden, Peter M. Allen

Human Movement Studies & Special Education Faculty Publications

Physical activity levels, hallucination experiences, sleep quality, and perceived stress were assessed using a survey administered to 57 adults with a confirmed diagnosis of Charles Bonnet Syndrome (CBS). Physical activity demonstrated a significant negative correlation with hallucination severity (r = –0.335, p = 0.011, two-tailed). A significant negative correlation was also observed between physical activity and perceived stress (r = –0.497, p < 0.001, two-tailed). In contrast, no significant association was identified between hallucination frequency and sleep disruption or insomnia. These findings suggest that engaging in appropriate levels of physical activity may help reduce the severity of hallucinations and mitigate stress among individuals with CBS. The observation that higher levels of physical activity are associated with reduced hallucination burden may help the development of evidence-based management strategies for CBS. Additionally, the finding that physical activity was significantly related to hallucination severity, whereas sleep disruption was not, merits deeper exploration in future research.

Decreased Exercise-Induced Pulmonary Capillary Recruitment In Pulmonary Arterial Hypertension, David Langleben, Stylianos E. Orfanos, Benjamin D. Fox, Michele Giovinazzo, Magali Kaddis, John D. Catravas

Bioelectrics Publications

The human lung normally accommodates exercise-induced cardiac output increases mainly via recruitment of non-concomitantly perfused pulmonary capillaries. Recruitment is detectable by measuring the first-pass transpulmonary metabolism of ³H-benzoyl-Phe-Ala-Pro, providing an estimate of functional capillary surface area (FCSA). Pulmonary arterial hypertension (PAH) results from luminal narrowing of small precapillary arterioles, reducing downstream perfused FCSA. We hypothesized that exercising PAH patients would not be able to recruit FCSA normally. We studied two patients with severe PAH. Despite exercising to maximal dyspnea, neither could recruit FCSA. These limited data are the first direct measurements of FCSA in exercising PAH patients.

Metabolic Reprogramming Following Mitochondrial Transfer Between Idh2-Mutant Chondrosarcoma Cells And A Normal B-Cell Line, Caleb Wyckoff, Christopher Osgood, Ellen Jing, Michael Stacey

Bioelectrics Publications

Background/Objectives: Chondrosarcoma, glioblastoma, acute myeloid leukemia, chronic lymphocytic leukemia, and cholangiocarcinoma cancers all contain mutations in the gene isocitrate dehydrogenase 2 (IDH2). The mutant IDH2 enzyme metabolizes alpha-ketoglutarate (αKG) into the potent oncometabolite D-2-hydroxyglutarate (D2HG) in the mitochondria of these cancers, leading to altered cellular metabolism. Emerging evidence suggests that mitochondrial transfer between cancer and recipient cells represents an important form of intercellular communication that may influence cellular metabolism. The presence of intercellular TNTs between IDH2-mutant chondrosarcoma cells motivated an investigation into mitochondria-associated physiological changes occurring during an intercellular exchange with immune cells. A mitochondrial transfer is a two-way …

Short Term Trends In Benthic Macroinvertebrate Communities Downstream Of Iron Gate Dam Before And During Klamath Dam Removal, Rosa Cox

Cal Poly Humboldt theses and projects

Dam removals are increasingly being used to restore connectivity and ecological function to rivers degraded by impoundments, yet the short-term ecological impacts of large-scale dam removals remain poorly understood. In 2023-2024, four hydroelectric dams were removed from the Klamath River in Northern California and southern Oregon, mobilizing large volumes of fine sediments stored in reservoirs.  This study evaluated short-term trends in benthic macroinvertebrate (BMI) communities within the first ~90 km downstream of the Klamath dam removal project reach by comparing benthic kick net, invertebrate drift, and juvenile salmonid diet samples before (2022-2023) and during (2024) dam removal at paired mainstem …

Geographic Variation In Proteomic Responses To Ocean Acidification In A Cold-Water Coral (Balanophyllia Elegans), Keana A. Richmond

Cal Poly Humboldt theses and projects

In the face of a rapidly changing climate, assessing organismal responses to future stressors in the context of current, natural exposure to stress could provide key insights to understanding marine ecosystem resilience. I used Balanophyllia elegans, a cold-water, solitary, azooxanthellate coral as a model to better understand how varying oceanographic conditions across its geographic range have shaped its ability to tolerate and potentially adapt to current and future ocean acidification conditions. I collected B. elegans individuals from four sites across 2,500km of their range and subjected them to two pH treatments to investigate site-specific protein expression in response to …

Bacterial Community Function In Pitcher Plant Leaves As An Experimental And Mathematical Model Of Functional Dynamics, Amelia Jackson

Cal Poly Humboldt theses and projects

This work looks at two different sites with differing abiotic factors in measures of altitude, temperature and precipitation. The site with higher altitude, larger temperature range, and lower precipitation, located in Plumas National Forest (Quincy, CA), had a flat BEF trend that suggests functional redundancy The site with lower altitude, more moderate temperatures, and higher precipitation located in Six Rivers National Forest (Gasquet, CA), also had a flat BEF trend. These abiotic factors could correlate to the significantly different bacterial compositions between sites. The second portion of this work is modeling the host antagonist relationship between Eyxra moths and their …

Nutrient-Driven Transcription Factor-Dna Interactions And Their Signaling Mechanisms In Metabolic Disease, Evelyn A. Bates

Theses and Dissertations--Nutritional Sciences

Metabolic homeostasis is maintained through tightly coordinated signaling networks that integrate diverse physiological inputs. Central to this regulation are transcription factors, which sense nutrient, hormonal, and vitamin-derived signals and translate them into coordinated gene expression programs. Transcription factor activity is governed by DNA binding, recruitment of coregulatory proteins, and interactions with specific response elements in gene promoters, which allows them to selectively modulate diverse metabolic pathways. Owing to their multifactorial and tunable nature, transcription factors have emerged as promising targets for the treatment and diagnosis of metabolic diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD). This dissertation explores the molecular …

Seasonal And Lunar Patterns Of Peach Blossom Jellyfish (Craspedacusta Sowerbii) In Michigan, Claire Kozal

Master's Theses and Doctoral Dissertations

The peach blossom jellyfish (Craspedacusta sowerbii) is the only freshwater medusa found in the United States, yet its distribution, abundance, and mechanisms of dispersal remain poorly understood. Given its uncertain status, understanding the ecology of this species is a priority. To characterize population dynamics during the medusa season, surface water temperature and medusa abundance were surveyed at six inland lakes in Michigan. Occurrence records of C. sowerbii in Michigan were then used to compare co-occurrence patterns with nine aquatic invasives as a window into potential dispersal mechanisms and to create a regional ecological niche model. Medusae were observed in one …

Impact Of Powdered Tart Cherry Supplementation On Performance Recovery Following Repeated Sprint Exercise, Anthony M. Hagele, Kyle S. Levers, Kevin F. Holley, Alex C. Schrautemeier, Joesi M. Krieger, Joshua M. Iannotti, Connor J. Gaige, Ralf Jäger, Chad Kerksick

Faculty Scholarship

Background: Due to its high polyphenol content and purported capability to mitigate post-exercise muscle soreness and promote recovery, tart cherry (TC) supplementation has been proposed to enhance recovery and athletic performance. This study examined the effects of powdered TC supplementation on various recovery and performance metrics following a repeated sprint exercise protocol in physically active young adults.

Methods: 40 (18 M, 22 F) healthy, active participants (24.6 ± 5.5 yrs, 171.5 ± 11 cm, 71.7 ± 14.5 kg, 24.2 ± 3.1 kg·m−2) participated in this randomized, double-blind, placebo-controlled, parallel study design. Placebo (PLA) or powdered TC supplementation (500 …

Beyond Ssris: Omega-3 Fatty Acids And The Neurobiology Of Impulsivity In Borderline Personality Disorder, Sujean Doo

Scripps Senior Theses

Impulsivity is a central and clinically significant dimension of Borderline Personality Disorder (BPD), and is strongly associated with self-harm, aggression, and suicide risk. Despite its prognostic importance, pharmacologic management of impulsivity in BPD remains inconsistent. Selective serotonin reuptake inhibitors (SSRIs) are frequently prescribed; however, randomized controlled trials demonstrate limited efficacy for impulsive-aggression, and some patients experience a paradoxical behavioral activation. Meta-analytic and systematic reviews further suggest that mood stabilizers and second-generation antipsychotics may outperform antidepressants, yet no specific medication is indicated to target impulsive behavioral dyscontrol.

This thesis synthesizes findings from systematic reviews, randomized trials, and neuroimaging research to evaluate …

The Effect Of Sleep Environment On Sleep Quality And Behavior In Firefighters: A Cross-Sectional Study, Jacquelyn N. Zera, Erica Esper, Anna Peluso Simonson, Ashley N. Clausen, Serena Paterno

2026 Faculty Bibliography

Firefighters face high-stress occupational demands and irregular shift work that negatively impact sleep quality, which is intrinsically linked to long-term physical and psychological health. This cross-sectional study examines how the physical sleep environment (home vs. work) and station sleeping arrangements (bunk-style vs. individual dorm-style quarters) influence subjective sleep quality in this population. Sixty-six career firefighters (Age = 40.89 ± 11.05 years), completed the Pittsburgh Sleep Quality Index (PSQI) to assess their sleep in both home and fire station environments, with data analyzed using Wilcoxon Signed Ranks and Mann–Whitney U tests. The results reveal significant differences (p < 0.001), with sleep duration, efficiency, subjective quality, and global PSQI scores all performing significantly better at home than at work. Notably, no significant differences were found between bunk-style and dorm-style sleeping quarters at the station. These findings suggest that firefighters experience poorer sleep while on duty regardless of room design, indicating that operational stressors like call volume and nocturnal arousal may be more influential on sleep quality than the physical arrangement of sleeping quarters, and could inform organizational policies and wellness programs aimed at reducing occupational fatigue.

Dietary Intake And Predictors Of Healthy Eating In Midwestern American College Students: An Observational Study †, Anna Peluso Simonson, Jacquelyn N. Zera, Gregory S. Farnell

2026 Faculty Bibliography

College students often maintain poor dietary habits, notably low fruit and vegetable intake. Commonbarriers include limited time, cost, and lack of nutritional knowledge. This study examined dietary behaviors, barriers, and factors influencing Healthy Eating Scores (HES) amongcollege students. Participants (N = 224; age = 20.3 ± 2.5 years, BMI = 23.9 ± 4.1 kg/m2, 78.9% female, and 91.3% white) completed an online survey. Results indicate meat overconsumption with underconsumption of water, fruits, and vegetables. Limited time and healthy options were the primary perceived barriers. Tests of between-subject effects identified gender (F = 4.38, p = 0.04) and living situation (F …

A Thymine Dimer Stalls A High-Fidelity Dna Polymerase By Providing No Template Information In The Same Manner As An Abasic Site, Amanda R. Walsh, Hye Rhee Kim, Lorena S. Beese, Eugene Y. Wu

Biology Faculty Publications

Cyclobutane pyrimidine dimers are photolesions that form when UV-B irradiation causes adjacent thymine or cytosine bases to covalently bond and can arrest DNA synthesis by replicative polymerases. To gain insight into the effects of cis-syn cyclobutane thymine dimers (T=T) on DNA replication in a model polymerase, we conducted solution and crystallographic studies of the Bacillus DNA polymerase I large fragment (BF) in complex with a T=T-containing template and an incoming dNTP. A thymine dimer lesion blocked nucleotide addition by BF in solution. The crystal structure of the BF-T=T-dATP complex indicated that the thymine dimer is too large to enter the …

Precision Metagenomics Reveals Microbial Landscape In Acute Upper Respiratory Infections: A Comprehensive Dataset, Sadia Almas, Rob E. Carpenter, Vaibhav K. Tamrakar, Anuradha Singh, Aditya Sharma, Rahul Sharma

Human Resource Development Faculty Publications and Presentations

Objectives The comprehension of the microbial composition in upper respiratory tract infections is pivotal for the progression of diagnostic and treatment methodologies. This article presents a dataset derived from Precision Metagenomic next-generation sequencing using hybridization capture-based targeted sequencing. Nasopharyngeal samples from 24 patients with acute URIs were analyzed using the Illumina®/IDbyDNA Respiratory Pathogen ID/ AMR panel. The dataset contains a wealth of information on the composition of the microbiota, including the relative abundance of known pathogens and their potential clinical significance. Data description This dataset serves as a valuable asset for future research in respiratory medicine, infectious disease epidemiology, antimicrobial …

Soil Respiration Drivers And Challenges In A Changing Environment, Olivia Rae Haas

Theses, Dissertations and Culminating Projects

This study aims to understand post agricultural forested soils (sandy loam, silt loam, and loam) and the influences that drive carbon sequestration and soil respiration flux. Duke Farms in Hillsborough NJ, has historically been utilized as an agricultural zone for farming a variety of crops. Currently the area is protected with a focus on environmental conservation and restoration of the land. This includes getting a better understanding of the forested portions of the property. Understanding the quality of forested areas is vital as they have the potential to act as a carbon sink which can mitigate the effects of climate …

Effect Of Mid-Range Ultraviolet Light On Avian Embryonic Development, Keelie Hughes

Biology Theses

While it is a known fact that specific environmental conditions must be met to ensure proper embryonic development, the impact of changes in this delicate balance is unclear. Ultraviolet (UV) light has a narrow range of effectiveness in mature tissue, where too little can hinder molecular signaling and too much can cause damage to genetic material. This study exposed in ovo chicken embryos in the preliminary stages of development to mid-range UV radiation to examine developing embryo and tissue morphology using anthropometric methods and comparing proliferative cells among embryos exposed to varying doses of UV light. Additionally, quantitative polymerase chain …

Design And Fabrication Of A Scaled Automated Dairy Farm Model: A Report, Md Towfiqur Rahman

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Summary

This study investigates how ventilation systems work in dairy barns and builds a scaled model to support education and research. The project is designed to help students from the University of Nebraska–Lincoln (UNL), K-12 learners, and researchers in animal science, veterinary medicine, and engineering gain visual experience with dairy facility components and processes. Different ventilation methods were studied, leading to the design of a 1/64-scale tunnel-ventilated dairy barn meant for 60 Holstein Friesian cows. Barn dimensions were set based on real Holstein cow measurements to ensure proper cow comfort, while airflow requirements were calculated and scaled down. Miniature fans …

Mapping Coastal Vegetation To Evaluate Salt Marsh Decline From 2016 To 2025 In South Carolina, Usa, Zak Henry Bartholomew

Theses, Dissertations and Capstones

Accelerating sea-level rise and storm surge events pose a substantial threat to salt marsh ecosystems, which provide critical ecosystem services. Classification and mapping of coastal vegetation through remote sensing can identify marsh dieback events and provide spatial context for patterns of marsh vulnerability. We used a multi-sensor approach that incorporated LiDAR data, multispectral imagery, and field-derived cover estimates to classify Spartina alterniflora (smooth cordgrass) dominated marsh types on Marine Corps Recruit Depot Parris Island (MCRDPI), a sea island in South Carolina, USA. In summer 2025, surveys were conducted within marsh classes to collect training and validation data. We used random …

Do Magnesium Ions Have Similar Effects As Calcium Ions On Resting Membrane Potential?, Anthony Hana, Youngwoo Kim, Joy Bidros, Katie Neglia, Robin L. Cooper

Biology Faculty Publications

Maintaining a membrane electrical potential of biological cells is a dynamic process, as some cells have a continually changing potential, like pacemaker cells, while other cells may function with large or small changes in the membrane potential. Additionally, some cells may change their electrical potential when stimulated or inhibited by electrical signals, chemical compounds, or both—either simultaneously or episodically. The persistent leak of K⁺ through two-pore-domain potassium channels (K2P) and of Na⁺ through Na⁺ leak channels (NALCNs) and the action of pumps and exchangers are primarily responsible for maintaining a resting potential. Ca²⁺ ions are known …

Exogenous Estradiol Does Not Regulate Daily Metabolic Rhythms Underlying Diet-Induced Obesity In Male Mice, W. Brad Osborne, Oliver Vöcking, Victoria Alvord, Oluwabukola Omotola, Yuriko Katsumata, Julie S. Pendergast

Biology Faculty Publications

Male mice fed high-fat diet become obese, but female mice are resistant to diet-induced weight gain. We previously found that circulating estradiol in females protects their daily rhythms from disruption by high-fat feeding to prevent diet-induced obesity. The goal of this study was to determine the effects of estradiol on daily metabolic rhythms in male mice. Male C57BL/6J mice were treated with estradiol and fed high-fat diet for 2 weeks. We measured the effects of high-fat diet feeding on daily rhythms of eating behavior and locomotor activity, and on the phases, or timing, of circadian rhythms in central and peripheral …

Drinking Microstructure Analysis Of Direct Controls Of Water Intake In Male And Female Rats, Bo W. Sortman, Emalie L. Mullane, Kennedy L. Lamb, Andrea A. Edwards, Ann-Marie Torregrossa, Derek Daniels, Jessica Santollo

Biology Faculty Publications

Measures of rodent drinking (lick) patterns are used to test how various manipulations affect fluid intake. Decades of research indicate that manipulating the satiating potency of a stimulus affects the number of licking bursts whereas manipulating the hedonic value of the solution affects the size of the licking bursts or rate of licking. This type of analysis has been largely applied to manipulations that modulate drinking that is already occurring (i.e., indirect controls or modulators of intake), but there is a dearth of studies with detailed measures of licking due to stimuli that are primary drivers of intake which happen …

Evolution Of A Novel Neuronal Sex-Specifically Spliced Gene In Mosquitoes, Yael Norohasimbola Tsitohay

Student Theses and Dissertations

Female mosquitoes from many species require a blood meal from an animal host as a protein source for egg development and successful reproduction. The majority of mosquito species are generalists in their host preference, feeding on a range of animals including mammals, birds, and amphibians. However, a small fraction of mosquito species have evolved a preference for human hosts. These species are mainly found in the genera Aedes, Culex, and Anopheles, and they have created a global health crisis due to their ability to transmit deadly human pathogens including dengue virus, Zika virus, West Nile Virus, and …

Reproductive Success Is Secured By A Rapidly-Evolving Short Peptide In Female Aedes Aegypti Mosquitoes, Priyanka Lakhiani

Student Theses and Dissertations

The mosquito lineage spans hundreds of millions of years of evolution, and this period has honed the yellow fever mosquito, Aedes aegypti, into a precise and expert predator. While nectar and plant-derived carbohydrates are sufficient sources of nutrition to maintain energy and metabolism, female mosquitoes must acquire multiple ingredients to successfully reproduce and produce offspring. Healthy, motile sperm from a conspecific male and a complete blood meal from a human host are required for females to develop viable eggs, and thus ensure species survival. What are the internal mechanisms that coordinate the acquisition of these key elements with the maturation, …