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Lakota Plant Lesson Connecting Science And Culture For 2nd Graders, Jade M. Jupackal, Larry Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Lydia Yellow Hawk, Jessica Larson, Michael Prate, Madhav P. Nepal Aug 2025

Lakota Plant Lesson Connecting Science And Culture For 2nd Graders, Jade M. Jupackal, Larry Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Lydia Yellow Hawk, Jessica Larson, Michael Prate, Madhav P. Nepal

iLEARN Teaching Resources

In this lesson, 2nd graders will learn about how the Lakota people use plants and why these plants are special. They will also discover the important parts of a plant—roots, stem, leaves, flowers, and seeds. Students will engage in activities like coloring, drawing, and exploring real plants found in schoolyard to help them understand each plant part and its function. This culturally responsive lesson blends science with experiential learning and emphasizes plant-people relationships. By the end, students will complete an art-based assessment to demonstrate understanding.


Opposing Roles For Iron Transport Systems In Gallium Tolerance In Extraintestinal Pathogenic Escherichia Coli, Nagama Parveen Aug 2025

Opposing Roles For Iron Transport Systems In Gallium Tolerance In Extraintestinal Pathogenic Escherichia Coli, Nagama Parveen

Theses and Dissertations

Iron is required for bacterial growth because it serves as a co-factor for enzymes involved in DNA synthesis, cellular respiration, and other processes. Disrupting bacterial iron homeostasis is an effective strategy to prevent the growth of antibiotic-resistant bacteria, and gallium (Ga³⁺) has emerged as a promising candidate due to its ability to displace iron (Fe³⁺) and prevent essential iron-dependent pathways. However, Escherichia coli are naturally less sensitive to gallium than many other bacteria, and the mechanisms that control gallium tolerance are not completely understood. To address this, we performed a genome-wide transposon sequencing (TnSeq) screen to identify genes important for …


Buffalo Stories & Science For 4th Graders, Ashley A. Duffy, Larry M. Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Lydia Yellow Hawk, Jessica Larson, Michael Prate, Madhav P. Nepal Aug 2025

Buffalo Stories & Science For 4th Graders, Ashley A. Duffy, Larry M. Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Lydia Yellow Hawk, Jessica Larson, Michael Prate, Madhav P. Nepal

iLEARN Teaching Resources

In this culturally responsive science lesson, students explore the ecological and historical importance of buffalo through story and hands-on learning. Using Paul Goble’s Return of the Buffaloes, learners’ journey into Lakota legend to discover how buffalo sustained communities and symbolized connection to land and spirit. Through guided reading, students uncover how buffalo supported Indigenous survival—providing food, shelter, clothing, and tools—while developing an appreciation for traditional knowledge systems and biodiversity. Students then deepen their understanding of food science by making buffalo jerky, connecting past and present preservation methods. As they mix ingredients, shape meat into strips, and observe dehydration techniques, students …


Indirect Dna Transfer To Duct Tape Rolls Stored In Cars, Yuching Chung Aug 2025

Indirect Dna Transfer To Duct Tape Rolls Stored In Cars, Yuching Chung

Student Theses

This project investigated the accumulation of DNA on duct tape rolls stored in cars. Specifically, we analyzed samples recovered from three areas (the inside, outside, and flat sides) of unused duct tape stored under the driver's seat and trunk of cars for seven days. Twelve volunteers were recruited, resulting in 64 DNA samples from 12 cars. We evaluated DNA quantities and STR genotyping outcomes after amplification with the GlobalFiler™ kit. On average, the DNA yields from under the driver's seat were higher than from the trunk, but the difference was not significant. The inside of the tape roll yielded significantly …


The Ring-Finger Ubiquitin E3 Ligase Rfel1 Targets Wheat Npr3 For Degradation To Confer Broad-Spectrum Resistance Against Biotrophic Fungal Pathogens, Liuhui Qiao, Kunpu Zhang, Jinyan Li, Ziming Zhang, Xiao Sun, Huiyun Liu, Ziyue Li, Nannan Ni, Ximei Ma, Jianhui Zhao, Guangwei Li, Xiaohuan Jin, Wenming Zheng, Daowen Wang, Zheng Qing Fu, Huan Wang Aug 2025

The Ring-Finger Ubiquitin E3 Ligase Rfel1 Targets Wheat Npr3 For Degradation To Confer Broad-Spectrum Resistance Against Biotrophic Fungal Pathogens, Liuhui Qiao, Kunpu Zhang, Jinyan Li, Ziming Zhang, Xiao Sun, Huiyun Liu, Ziyue Li, Nannan Ni, Ximei Ma, Jianhui Zhao, Guangwei Li, Xiaohuan Jin, Wenming Zheng, Daowen Wang, Zheng Qing Fu, Huan Wang

Faculty Publications

No abstract provided.


Integrating Ctdna Analysis And Radiomics For Dynamic Risk Assessment In Localized Lung Cancer, Everett J Moding, Mohammad Shahrokh Esfahani, Cheng Jin, Angela B Hui, Barzin Y Nabet, Yufei Liu, Jacob J Chabon, Michael S Binkley, David M Kurtz, Emily G Hamilton, Aadel A Chaudhuri, Chih Long Liu, Zhe Li, Rene F Bonilla, Alice L Jiang, Brianna C Lau, Pablo Lopez, Jianzhong He, Yawei Qiao, Ting Xu, Luyang Yao, Saumil Gandhi, Zhongxing Liao, Millie Das, Kavitha J Ramchandran, Sukhmani K Padda, Joel W Neal, Heather A Wakelee, Michael F Gensheimer, Billy W Loo, Ruijiang Li, Steven H Lin, Ash A Alizadeh, Maximilian Diehn Aug 2025

Integrating Ctdna Analysis And Radiomics For Dynamic Risk Assessment In Localized Lung Cancer, Everett J Moding, Mohammad Shahrokh Esfahani, Cheng Jin, Angela B Hui, Barzin Y Nabet, Yufei Liu, Jacob J Chabon, Michael S Binkley, David M Kurtz, Emily G Hamilton, Aadel A Chaudhuri, Chih Long Liu, Zhe Li, Rene F Bonilla, Alice L Jiang, Brianna C Lau, Pablo Lopez, Jianzhong He, Yawei Qiao, Ting Xu, Luyang Yao, Saumil Gandhi, Zhongxing Liao, Millie Das, Kavitha J Ramchandran, Sukhmani K Padda, Joel W Neal, Heather A Wakelee, Michael F Gensheimer, Billy W Loo, Ruijiang Li, Steven H Lin, Ash A Alizadeh, Maximilian Diehn

Faculty, Staff and Student Publications

The complementarity and clinical utility of combining liquid biopsies and radiomic image analysis has not been demonstrated. Circulating tumor DNA (ctDNA) minimal residual disease after chemoradiotherapy (CRT) for non-small cell lung cancer (NSCLC) is highly prognostic, but on-treatment biomarkers are needed to enable response-adapted therapies. Here, we analyzed 418 patients with NSCLC undergoing CRT to develop and validate a novel dynamic risk model that accurately predicts ultimate progression-free survival during treatment. We optimize tissue-free variant calling from plasma samples to facilitate ctDNA monitoring and demonstrate the importance of accounting for persistent clonal hematopoiesis variants. We show that mid-CRT ctDNA concentration …


Landscape Of Clinical Trials In Cancer Cachexia: Assessment Of Trends From 1995-2024, Ana Regina Cabrera, Kaitlyn Parker, Deena B. Snoke, Bart Hammig, Nicholas P. Greene Aug 2025

Landscape Of Clinical Trials In Cancer Cachexia: Assessment Of Trends From 1995-2024, Ana Regina Cabrera, Kaitlyn Parker, Deena B. Snoke, Bart Hammig, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Background Cancer cachexia, a multifactorial syndrome characterized by unintentional weight loss, is a frequent complication of cancer that impacts patients' quality of life and survival.

Methods In this retrospective review, we evaluated the landscape of clinical trials registered on ClinicalTrials.gov for the consideration of potential factors contributing to biological human heterogeneity in their design and analyses.

Results Among clinical trials registered from 1995-2024, we observed increased inclusion of female participants, but lack of reporting of sex as a biological variable. The majority (similar to 93%) of participants were of Caucasian descent. There was a substantial divergence in the diagnostic criteria …


Volumetric Imaging Of Cellular Dynamics Using Light-Sheet Microscopy: From Subcellular Structures To Whole Organisms, Md Nasful Huda Prince Aug 2025

Volumetric Imaging Of Cellular Dynamics Using Light-Sheet Microscopy: From Subcellular Structures To Whole Organisms, Md Nasful Huda Prince

Optical Science and Engineering ETDs

Advancing biomedical imaging requires platforms that combine high-resolution, speed, and stability across biological scales. This dissertation presents three innovations designed to address limitations of conventional light-sheet and oblique plane imaging. First, we introduce Reflected Inline Detection in Epi-Oblique Plane Microscopy (RIDE-OPM), a compact and drift-resistant system that eliminates a tertiary detection path while maintaining alignment flexibility, enabling robust long-term live imaging. Second, we present a high-speed Axially Swept Light-Sheet Microscopy (ASLM) platform for cleared tissues, using dual foci and synchronized sweeping to achieve isotropic sub-micron resolution at up to 40 frames-per-second, a fourfold improvement over standard ASLM. Integrated with a …


Gated Recurrent Unit With Decay Has Real-Time Capability For Postoperative Ileus Surveillance And Offers Cross-Hospital Transferability, Xiaoyang Ruan, Sunyang Fu, Heling Jia, Kellie L Mathis, Cornelius A Thiels, Schaeferle M Gavin, Patrick M Wilson, Curtis B Storlie, Hongfang Liu Aug 2025

Gated Recurrent Unit With Decay Has Real-Time Capability For Postoperative Ileus Surveillance And Offers Cross-Hospital Transferability, Xiaoyang Ruan, Sunyang Fu, Heling Jia, Kellie L Mathis, Cornelius A Thiels, Schaeferle M Gavin, Patrick M Wilson, Curtis B Storlie, Hongfang Liu

Faculty, Staff and Student Publications

Background: Ileus, a postoperative complication after colorectal surgery, increases morbidity, costs, and hospital stays. Assessing risk of ileus is crucial, especially with the trend towards early discharge. Prior studies assessed risk of ileus with regression models, the role of deep learning remains unexplored.

Methods: We evaluated the Gated Recurrent Unit with Decay (GRU-D) for real-time ileus risk assessment in 7349 colorectal surgeries across three Mayo Clinic sites with two Electronic Health Record (EHR) systems. The results were compared with atemporal models on a panel of benchmark metrics.

Results: Here we show that despite extreme data sparsity (e.g., 72.2% of labs, …


Unci Maka’S Gift: An Outdoor Science Adventure For The First Graders, Arlene A. Abao, Larry M. Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Jessica Larson, Lydia Yellow Hawk, Michael Prate, Madhav P. Nepal Aug 2025

Unci Maka’S Gift: An Outdoor Science Adventure For The First Graders, Arlene A. Abao, Larry M. Browning, Matt Miller, Jiyul Chang, Srinivas Janaswamy, Jessica Larson, Lydia Yellow Hawk, Michael Prate, Madhav P. Nepal

iLEARN Teaching Resources

In this super-fun lesson, kids are going outside to explore the schoolyard! They will look for all sorts of amazing plants, also called flora. They will use a special tablet to help us learn their names and then draw pictures of them. They will also dig a little to see the soil and learn why it's so important for plants to grow big and strong. And guess what? They’ll even look for little animals like ants or butterflies, also called fauna, that live near the plants, because everything in nature works together! They'll also hear cool stories about how people …


Culturally Responsive Teaching: Identifying Conifers Through Science And Tradition, Madhav P. Nepal Aug 2025

Culturally Responsive Teaching: Identifying Conifers Through Science And Tradition, Madhav P. Nepal

iLEARN Teaching Resources

This lesson on plant taxonomy introduces students to the scientific system used to name, classify, and identify plant species, with a focus on conifer trees found in local environments. Students explore how observable traits—such as needle shape, cone structure, and bark texture—are used to group plants into categories that reflect their evolutionary relationships. Through a hands-on tree-walk activity, students use a simplified dichotomous key to identify at least five conifer species on or near school grounds. They then use digital plant ID tools to confirm their findings and compare traditional and modern identification methods. The lesson also emphasizes the hierarchical …


Quantile Index Predictors Using R Package Hyper.Gam, Tingting Zhan, Misung Yi, Inna Chervoneva Aug 2025

Quantile Index Predictors Using R Package Hyper.Gam, Tingting Zhan, Misung Yi, Inna Chervoneva

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

MOTIVATION: Evaluation of single-cell protein expression from immunohistochemistry images is used increasingly in biomedical research. Many proteins are used solely for phenotyping cells in the tumor microenvironment. Other proteins with meaningfully quantitative expression levels provide so-called functional protein biomarkers. There is still a limited number of methods and software tools available for utilizing the entire distributions of single-cell expression levels.

RESULTS: We present the R package hyper.gam, providing a supervised learning framework for deriving biomarkers based on single-cell distribution quantiles. The single-cell data are first converted into sample quantile functions, which are then used as predictors in scalar-on-function regression models …


Sex, Stress And Hormones : The Role Of Modifiable Risk Factors In The Kinetics Of Alzheimer’S Disease, Hannah Marie Edwards Aug 2025

Sex, Stress And Hormones : The Role Of Modifiable Risk Factors In The Kinetics Of Alzheimer’S Disease, Hannah Marie Edwards

Arts & Sciences Graduate Student Theses and Dissertations

Alzheimer’s Disease (AD) is a neurodegenerative disease hallmarked by the presence of amyloid- plaques and tau tangles in the brain. The process of the disease begins decades prior to the onset of symptoms and is thought to be driven first by a buildup of amyloid- peptide in the extracellular space, triggering a cascade of pathology and symptomology culminating in loss of cerebral volume and cognitive impairment. Women are diagnosed with AD at a rate 2/3 higher than their male counterparts, even when controlling for age. While most driving factors of the disease are thought to be genetic, roughly 40% of …


Using Published Undergraduate Biomechanics Research On Hydra Mouth Opening To Train Undergraduates, Stephen Hackler, T. Goel, Jonah Pacis , '25, Eva-Maria S. Collins Aug 2025

Using Published Undergraduate Biomechanics Research On Hydra Mouth Opening To Train Undergraduates, Stephen Hackler, T. Goel, Jonah Pacis , '25, Eva-Maria S. Collins

Biology Faculty Works

Biophysics research is exciting because physical approaches to biology can provide novel insights, and it is challenging because it requires knowledge and skills from multiple disciplines. We have developed an undergraduate biophysics laboratory module that teaches fundamental skills such as time-lapse microscopy, image analysis, programming, critical reading of scientific literature, and basics of scientific writing and peer review. The module is accessible to students who are familiar with introductory statistics, cell biology, and differential calculus. We used published research on the biomechanics of Hydra mouth opening as a framework because it describes a stunning biological phenomenon: Hydra, a freshwater …


Advanced Interactions Of Directed Energy With Retinal Pigment Epithelial Cells And Their Photochemical And Photothermal Responses, Jin B. Ha Aug 2025

Advanced Interactions Of Directed Energy With Retinal Pigment Epithelial Cells And Their Photochemical And Photothermal Responses, Jin B. Ha

Theses & Dissertations

Excess optical radiation can injure the retina through either rapid heat deposition (photothermal damage) or cumulative photo‑oxidative stress (photochemical damage), yet current laser‑safety limits treat these mechanisms as independent. To test that assumption, this dissertation integrated systematic wavelength, duration and temperature‑controlled laser exposures with live/dead fluorescence imaging in a melanin‑loaded hTERT‑RPE1 monolayer model. First, concurrent 447 nm (blue) and 2 µm (infra‑red) beams delivered for 200 s demonstrated a strong thermal–photochemical synergy: each beam alone was sub‑threshold (≤25 % lethality) but together produced 100 % RPE death without exceeding 50 °C, proving that modest heating markedly lowers the photon dose …


The Effect Of An Invasive Species (Lantana Camara) And A Fast-Growing Herb (Acanthus Pubescens) On The Plant And Animal Communities In Kibale National Park, Uganda, Kathleen Bufka Aug 2025

The Effect Of An Invasive Species (Lantana Camara) And A Fast-Growing Herb (Acanthus Pubescens) On The Plant And Animal Communities In Kibale National Park, Uganda, Kathleen Bufka

Theses and Dissertations

Fast-growing plant species, like Lantana camara and Acanthus pubescens, could threaten biodiversity in Kibale National Park, Uganda. I surveyed plants and wildlife in areas where these plants were frequently encountered compared to those areas where they are infrequent. I found mixed results based on plant traits and the animals considered. My findings support management efforts on these two species to prevent forest degradation.


A Pilot Study Exploring Vitamin D, Mental Health, And Gastrointestinal Health In Humans, Brianna C. Williams Aug 2025

A Pilot Study Exploring Vitamin D, Mental Health, And Gastrointestinal Health In Humans, Brianna C. Williams

Master's Theses

Mental disorders are experienced by nearly one billion people worldwide. Depression is one of the most common. Treatments exist, yet a devastating 75% of individuals suffering from depression do not receive adequate treatment. An emerging treatment strategy includes exploring the connection between mental health and nutrition, which includes the areas of gut health and nutrient deficiencies. Vitamin D is obtained through food, supplements, and sunlight. Many individuals are considered deficient (25[OH]D concentrations < 12 ng/mL) or insufficient (25[OH]D concentrations < 20 ng/mL). Purpose: This study aimed to explore mental and gastrointestinal (GI) health using surveys and lipopolysaccharide binding protein (LBP) concentrations, a biomarker of GI health, in individuals considered 25(OH)D deficient (DEF) vs not deficient (N-DEF). Methods: This cross-sectional study recruited physically active participants aged 18-45 years who underwent three evaluations in one visit. Health was assessed using surveys to evaluate mental health, GI symptoms, and vitamin D intake. Serum from fasting blood samples was used with an enzyme-linked immunosorbent assay to determine 25(OH)D and LBP concentrations. Unpaired t-tests were used to compare DEF vs N-DEF and significance was set at p < 0.05. Results: Thirty-two participants (mean age 25.3 ± 6.3 years) with mean and body fat percentage of 24.0% ± 10.7%, were placed into DEF (n=16) and N-DEF (n=16) categories. Interestingly, five of the 16 participants in DEF (31%) showed some level of depression (scores ranging from mild to severe) and only two of the 16 participants in N-DEF iv (13%) scored positively in the depression category (scores ranging from mild to moderate). Additionally, the participant with the lowest 25(OH)D concentration (5.42 ng/mL) was the only participant to meet the “severe” depression category criteria, with a score of 24 compared to other participants who scored within 0-16. Also, the only participant who scored “severe” in the stress category, was in the bottom 20% of 25(OH)D concentrations. As for GI health, the difference between average GI scores and average serum LBP concentrations between the groups were not statistically significant. Conclusion: There were no significant differences between DEF and N-DEF in perceived depression (p = 0.16), anxiety (p = 1.0), stress (p = 0.96), GI symptoms (P values ranged from 0.27 to 1.00), nor in LBP concentrations (p = 0.77). Funding: Support was received from the Graduate Student Association and College of Natural Health Sciences at the University of Northern Colorado.


Effects Of Chronic Marijuana Use On Postural Control During Quiet Standing, Johnathon S. Ashcraft Aug 2025

Effects Of Chronic Marijuana Use On Postural Control During Quiet Standing, Johnathon S. Ashcraft

Master's Theses

Marijuana, Cannabis Sativa, is the most commonly used recreational drug in the United States, with more than 60 million people reporting use in 2022 (Substance Abuse and Mental Health Services Administration, 2023). As marijuana consumption has increased, so have questions surrounding its acute and long-term effects. Its acute effects are well documented; however, the long-term effects are not as well understood. It is hypothesized that chronic marijuana users will exhibit a decrease in postural stability during quiet standing when compared to non-users, so the purpose of this study was to compare postural control of chronic marijuana users and non-users in …


Navigating Transportation Barriers: Older Adults’ Familiarity With New Mobility Options And Perceptions Toward Autonomous Vehicles In Arkansas, Arna Nishita Nithila, Suman Kumar Mitra, Michelle Gray, Alishia Juanelle Ferguson, Jennifer D. Webb Aug 2025

Navigating Transportation Barriers: Older Adults’ Familiarity With New Mobility Options And Perceptions Toward Autonomous Vehicles In Arkansas, Arna Nishita Nithila, Suman Kumar Mitra, Michelle Gray, Alishia Juanelle Ferguson, Jennifer D. Webb

Civil Engineering Faculty Publications and Presentations

The objective of this study is to analyze older adults’ familiarity with new transportation options (ride-hailing services, bike-share services, and shared e-scooter services) and their perception towards autonomous vehicles (fully autonomous cars), as well as how transportation barriers influence their familiarity and perceptions, in Arkansas, a predominantly rural state. Data from 775 older adults aged 60 years or older were collected between October 2021 and October 2022. To fulfill the study objective, the study used Latent Class Cluster Analysis to segment older adults into classes based on their familiarity with new transportation options and their perceptions of autonomous vehicles. The …


Pricing The Unknown: An Analysis Of Expected Value Of Young Horses And Price-Determining Factors, Rupasri Sura Aug 2025

Pricing The Unknown: An Analysis Of Expected Value Of Young Horses And Price-Determining Factors, Rupasri Sura

Graduate Theses and Dissertations

From a seller’s point of view in a market, it is crucial to plan the pricing strategies based on perceptions of buyer preferences and their willingness to purchase to ensure market success in selling and pricing. Applying this to the equine industry, this paper studies the factors determining the price of young horses (age ≤ 2 years) in digital auction platforms. Using data from Professional Horse Services, LLC (2012–2023), a Heckman’s two-step approach was employed, which involves a probit model as the first step and a hedonic price model as the second, aiming to correct for sample selection bias in …


Mode Regulates Alternative Nitrogenase Expression In Themethanogen Methanosarcina Acetivorans, Melissa Chanderban, Daniel J. Lessner Aug 2025

Mode Regulates Alternative Nitrogenase Expression In Themethanogen Methanosarcina Acetivorans, Melissa Chanderban, Daniel J. Lessner

Biological Sciences Faculty Publications and Presentations

All methanogens that can fix nitrogen use molybdenum (Mo) nitrogenase. Some methanogens, including Methanosarcina acetivorans, also contain alternative vanadium- and iron-nitrogenases, encoded by the vnf and anf operons, respectively. These nitrogenases are produced when there is insufficient Mo to support Mo-nitrogenase activity. The factors that control the expression of the alternative nitrogenases in response to Mo availability are unknown in methanogens. Here we show that ModE is the regulator that represses transcription of the vnf and anf operons in M. acetivorans when cells are grown with Mo. CRISPRi repression of modE results in a significant increase in the transcription of …


Night-Time Warming And Prey Availability Interact To Influence Physiology In Prairie Lizards (Sceloporus Consobrinus), Allison R. Litmer, Morgan K. Pelley, Steven J. Beaupre Aug 2025

Night-Time Warming And Prey Availability Interact To Influence Physiology In Prairie Lizards (Sceloporus Consobrinus), Allison R. Litmer, Morgan K. Pelley, Steven J. Beaupre

Biological Sciences Faculty Publications and Presentations

Among ectotherms, temperature and food availability are drivers of individual and population characteristics. Increasing night-time temperatures due to climate change can increase energetic demands, potentially amplified or mitigated by prey consumption. Few studies examine night-time temperatures specifically, and consequences of co-occurring changes in the abiotic and biotic environment. Thus, we examined interactions between warming night-time temperatures and prey availability (as a proxy of foraging time and effectiveness), and how they affect food consumption, digestive passage time, metabolizable energy intake (MEI), assimilated energy, and fecal and urate production in a model organism, prairie lizards (Sceloporus consobrinus). Three temperature treatments (current conditions, …


Invited Review: Effects Of Management On Performance Of Stocker Cattle And Subsequent Feedlot Performance: A Review Within Applied Animal Science, M.A. Snider, M.S. Gadberry, J.D. Rivera Aug 2025

Invited Review: Effects Of Management On Performance Of Stocker Cattle And Subsequent Feedlot Performance: A Review Within Applied Animal Science, M.A. Snider, M.S. Gadberry, J.D. Rivera

Animal Science Faculty Publications and Presentations

Purpose: The purpose of this review is to summarize relevant research from the journal Applied Animal Science (formerly known as The Professional Animal Scientist) between 1995 and 2024, that explores management practices and concepts as they relate to stocker calf performance and subsequent feedlot performance. A secondary objective of this review is to describe research trends and identify knowledge and research gaps within existing literature. Sources: Sources for this article included peer-reviewed scientific literature obtained from the journal Applied Animal Science, formerly known as The Professional Animal Scientist. Literature used in this review included original research, short communications, technical notes, …


Hyperspectral Indicators And Characterization Of Glyphosate-Induced Stress In Common Lambsquarters (Chenopodium Album L.), Mario Soto, Aurelie M. Poncet, Nilda Roma-Burgos, O. Wesley France, Juan C. Velasquez, Amanda J. Ashworth, Kristofor R. Brye, Cengiz Koparan Aug 2025

Hyperspectral Indicators And Characterization Of Glyphosate-Induced Stress In Common Lambsquarters (Chenopodium Album L.), Mario Soto, Aurelie M. Poncet, Nilda Roma-Burgos, O. Wesley France, Juan C. Velasquez, Amanda J. Ashworth, Kristofor R. Brye, Cengiz Koparan

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Hyperspectral sensors are increasingly used to develop optimized vegetation indices (VIs) that capture plant spectral response to specific stressors. The project goal was to develop quantitative metrics for characterization of weed response to herbicide application. This work applied hyperspectral sensing to describe and predict the spectral response of common lambsquarters (Chenopodium album L., CHEAL) to glyphosate application. Thirteen treatments, including one glyphosate rate used alone or in combination with eleven adjuvants plus one non- treated control, were applied to CHEAL seedlings cultivated in a greenhouse. Visible injury ratings and non- imaging hyperspectral data were collected 14 days after treatment application. …


A Multi-Isotope Investigation Of Mammoth Diet, Habitat, And Movement Patterns In The Central Great Plains, U.S.A., Jacob Mccloskey Aug 2025

A Multi-Isotope Investigation Of Mammoth Diet, Habitat, And Movement Patterns In The Central Great Plains, U.S.A., Jacob Mccloskey

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

During the Last Glacial Maximum (LGM), the Great Plains in Nebraska consisted of wooded parklands and grasslands, whereas spruce (Picea) forests, parklands, and steppe grasslands dominated east of the Missouri River. I analyzed bulk carbon (δ13C), oxygen (δ18O), and strontium (87Sr/86Sr) isotopes from tooth enamel in isolated mammoth (Mammuthus) molars to compare diet and movement patterns in two late Pleistocene assemblages: one in Nebraska (n = 24), and one in western Iowa and Missouri (n = 17). Furthermore, I identified a morphometric subset of molars as …


Alternative Therapeutics For Human Breast Cancer: Nutraceutical Underpinnings, In Vitro Metabolomic Profiling, Treatment Efficacy, And Contextual Ethical Implications, Aubrey A. Mattingly Aug 2025

Alternative Therapeutics For Human Breast Cancer: Nutraceutical Underpinnings, In Vitro Metabolomic Profiling, Treatment Efficacy, And Contextual Ethical Implications, Aubrey A. Mattingly

All Dissertations

Breast cancer remains one of the most prevalent diseases worldwide, yet therapeutic equity is still lacking. Standard treatments including surgery, radiotherapy, chemotherapy, and long-term hormone therapy. These approaches are often accompanied by significant side effects. While newer methods such as immunotherapy and targeted therapies have emerged, chemotherapy protocols and incorporation have remained largely unchanged in the past decades. In this context, nutraceuticals represent an alternative or adjuvant to therapy worthy of exploration. The reviewed literature highlights the anti-carcinogenic activity in selected nutraceuticals, marjoram, thyme and persimmon, considering their phytochemical constituents and secondary metabolites. Metabolomic profiling using the Biolog Phenotype Mammalian …


Advanced Specificity And Sensitivity Studies Relative To A Research Use Only Transcription-Mediated Amplification-Based Assay For Treponema Pallidum Rna Detection, Trinity Krueger, Grace Kadonsky, Elizabeth Thelen, Amanda Zapp, Josephine Moore, Ahmet Muslu, Allan Pillay, Irene A. Stafford, Erik Munson Aug 2025

Advanced Specificity And Sensitivity Studies Relative To A Research Use Only Transcription-Mediated Amplification-Based Assay For Treponema Pallidum Rna Detection, Trinity Krueger, Grace Kadonsky, Elizabeth Thelen, Amanda Zapp, Josephine Moore, Ahmet Muslu, Allan Pillay, Irene A. Stafford, Erik Munson

Clinical Lab Sciences Faculty Research and Publications

Preliminary experimentation has suggested that a research-use-only real-time transcription-mediated amplification assay for Treponema pallidum (RUO T. pallidum TMA) yields instances of T. pallidum nucleic acid detection that coincide with non-treponemal serology in men who have sex with men (MSM) at increased risk for sexually transmitted infection. To further characterize the specificity of RUO T. pallidum TMA testing, 3,586 rectal swab specimens reported as “not detected” by the assay generated a mean endpoint FAM fluorescence of 637.5 units. Introduction of Treponema denticola, Treponema phagedenis, and Treponema refringens nucleic acid into matrices generated mean endpoint FAM fluorescence ranging from 620.7 …


Multicenter Span Trial Of Fasudil In Ischemic Stroke, Takahiko Imai, Andreia Lopes De Morais, Xuyan Jin, Tao Qin, Jessica Lamb, Karisma A Nagarkatti, Mu-Hsun Chen, Ligia S B Boisserand, Rakesh B Patel, Mariia Kumskova, Anjali Chauhan, Krishnan M Dhandapani, Mohammad B Khan, Pradip K Kamat, Yanrong Shi, Suyi Cao, Basavaraju G Sanganahalli, Joseph B Mandeville, Patrick D Lyden, David C Hess, Enrique C Leira, Anil K Chauhan, Jaroslaw Aronowski, Louise D Mccullough, Raymond C Koehler, Lauren H Sansing, Márcio A Diniz, Cenk Ayata Aug 2025

Multicenter Span Trial Of Fasudil In Ischemic Stroke, Takahiko Imai, Andreia Lopes De Morais, Xuyan Jin, Tao Qin, Jessica Lamb, Karisma A Nagarkatti, Mu-Hsun Chen, Ligia S B Boisserand, Rakesh B Patel, Mariia Kumskova, Anjali Chauhan, Krishnan M Dhandapani, Mohammad B Khan, Pradip K Kamat, Yanrong Shi, Suyi Cao, Basavaraju G Sanganahalli, Joseph B Mandeville, Patrick D Lyden, David C Hess, Enrique C Leira, Anil K Chauhan, Jaroslaw Aronowski, Louise D Mccullough, Raymond C Koehler, Lauren H Sansing, Márcio A Diniz, Cenk Ayata

Children’s Nutrition Research Center Staff Publications

Background: The SPAN (Stroke Preclinical Assessment Network) is a confirmatory multicenter trial network to test cerebroprotective interventions in experimental acute stroke. In a first-of-its-kind trial, SPAN tested 6 interventions in a rodent model of transient focal ischemic stroke. Here, we report the efficacy of fasudil, an isoform-nonselective rho-associated kinase inhibitor, on primary and secondary outcomes in the SPAN trial.

Methods: Fasudil was administered at 10 mg/kg intraperitoneally every 12 hours for 6 doses starting 5 minutes before reperfusion in a 60-minute endovascular filament middle cerebral artery occlusion model. The active treatment arm (n=345) was compared with the pooled intraperitoneal and …


Family-Level Factors That Influence Physical Activity Among Hispanic Adolescents At Risk For Type 2 Diabetes, Sandra Mihail, Ayleen A Hernandez, Erica G Soltero Aug 2025

Family-Level Factors That Influence Physical Activity Among Hispanic Adolescents At Risk For Type 2 Diabetes, Sandra Mihail, Ayleen A Hernandez, Erica G Soltero

Children’s Nutrition Research Center Staff Publications

Objective: Family-based health promotion and disease prevention strategies are recommended as best practice; however, there is limited knowledge regarding the family-level factors that influence modifiable behavior risk factors like physical activity (PA) among Latinx adolescents. This study addressed this knowledge gap by using qualitative methods to identify perceptions of family-level factors that influence PA among Hispanic youth.

Methods: We conducted semistructured, open-ended interviews with 20 Latinx adolescents (14-16 years) with obesity (body mass index ≥95th percentile) to identify their perceptions of how family influences PA. Content analysis was used to identify emergent themes, which were then compared across demographic factors, …


Economic Contribution Of The Agricultural Sector To The Arkansas Economy In 2023, Frank Seo Aug 2025

Economic Contribution Of The Agricultural Sector To The Arkansas Economy In 2023, Frank Seo

AAES Research Reports and Research Bulletins

This report is the eighteenth in a series that examines agriculture’s economic contribution to the Arkansas economy. The total economic contribution of agriculture (direct, indirect, and induced effects) on value added, employment, and labor income was estimated with the Impact Analysis for Planning System (IMPLAN) for the most recent year available, 2023.