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Many Miles Away: A Cautionary Tale, Charles H. Smith

Faculty/Staff Personal Papers

Reporter Kerry Phillips is in for the surprise of her life: her television station has been contacted on a matter so important that 'scarcely anything could be of greater interest,' and she has been asked to follow up on the story. Little does she know just how interesting her job is about to get!

Love Of Life In Nine Developed And Underdevelopedcountries, Ahmed Abdel-Khalek Professor Of Psychology, Faculty Of Arts,, Mayssah El Nayal Professor Of Psychology, Faculty Of Human Sciences

BAU Journal - Health and Wellbeing

The present research sought to explore the differences between developed and underdeveloped countries on the Love of Life Scale (LLS). Nine samples (N =3,799) took part in the study. They were university students from Egypt, Lebanon, Kuwait, Qatar, Algeria, Malaysia, India, Iran, and USA. Sex-related differences in LLS were significant only in Kuwait (in favor of males) and India (in favor of females). The samples of Malaysia and U.S.A. obtained the highest mean LLS score, followed by participants from Qatar, India, and Kuwait, (males), and India, Iran, Qatar, and Algeria (females), respectively. The Pearson correlation of LLS with the World …

Quality Of Life And Well-Being Among Palestinianand Syrian Refugees In Lebanon, Mayssah El-Nayal Professor, Department Of Psychology, Faculty Of Human Sciences, Helga Alaeddine Assistant Professor, Department Of Psychology, Faculty Of Human Sciences, Olfat Mahmoud Assistant Professor (Part Timer), Department Of Psychology, Faculty Of Human Sciences

BAU Journal - Health and Wellbeing

Quality of life (QOL) is a basic concept in a number of disciplines, including social sciences, politics, economics, the environment, psychology, and medicine. Although the term comprises primarily psychological components, it remains a multi-dimensional concept that has been derived from various fields, the most important of which are biology, medicine, psychology, and sociology. Well-being generally includes global judgments of life satisfaction and feelings ranging from depression to joy. The study sought to (1) investigate the sex-related differences on both quality of life (QOL) and well-being. A convenience sample of 382 adults from the Palestinian and Syrian refugees were recruited. The …

Improving Indoor Air Quality Using Low-Emissionmaterials, Nael Alsarrag Assistant Professor, Faculty Of Architecture - Design & Built Environment

BAU Journal - Health and Wellbeing

The interior design field faces a technological breakthrough in the development of materials and methods of usage and implementation, which requires great attention for supportive studies The aim of this research is to improve indoor air quality by using lowemission materials with control and rationing the use of contaminant products in residential spaces And because human is the goal of every development and has the right to live in a healthy environment and healthy spaces, and mainly the success of any interior designer in all about taking care of this purpose that depends on the professional control and harnessing the …

Memantine Treatment Reduces The Incidence Of Flaccid Paralysis In A Zika Virus Mouse Model Of Temporary Paralysis With Similarities To Guillain-Barré Syndrome, Venkatraman Siddharthan, Hong Wang, Alexandre Lr De Oliveria, Xin Dai, John D. Morrey

Animal, Dairy, and Veterinary Science Faculty Publications

Clinical evidence suggests that Zika virus contributes to Guillain-Barré syndrome that causes temporary paralysis. We utilized a recently described Zika virus mouse model of temporary flaccid paralysis to address the hypothesis that treatment with an N-methyl-D-aspartate receptor antagonist, memantine, can reduce the incidence of paralysis. Aged interferon alpha/beta-receptor knockout mice were used because of their sublethal susceptibility to Zika virus infection. Fifteen to twenty-five percent of mice infected with a Puerto Rico strain of Zika virus develop acute flaccid paralysis beginning at days 8–9 and peaked at days 10–12. Mice recover from paralysis within a week of onset. In …

Mechanisms Of Sting-Associated Vasculopathy And Immunodeficiency, Brock Gordon Bennion

Arts & Sciences Graduate Student Theses and Dissertations

STING N153S in mice and STING N154S in humans cause spontaneous autoimmunity. Specifically, these mutations reduce the numbers of T cells and NK cells, and cause lung disease. However, mice develop perivascular lung inflammation that is distinct from the pulmonary fibrosis observed in human patients. Viral infections are known to exacerbate autoimmunity and foment pulmonary fibrosis. Therefore, we hypothesized that exposure to a virus may influence STING N153S disease in mice. To test this, we infected STING N153S animals with the gammaherpesvirus family member, gHV68, and found that 14 days post infection pulmonary fibrosis was readily observed by histological staining. …

Performance Of A Uv-A Led System For Degradation Of Aflatoxins B1 And M1 In Pure Water: Kinetics And Cytotoxicity Study, Judy Stanley, Ankit Patras, Brahmaiah Pendyala, Matthew J. Vergne, Rishipal R. Bansode

Agricultural and Environmental Sciences Faculty Research

The efficacy of a UV-A light emitting diode system (LED) to reduce the concentrations of aflatoxin B1, aflatoxin M1 (AFB1, AFM1) in pure water was studied. This work investigates and reveals the kinetics and main mechanism(s) responsible for the destruction of aflatoxins in pure water and assesses the cytotoxicity in liver hepatocellular cells. Irradiation experiments were conducted using an LED system operating at 365 nm (monochromatic wave-length). Known concentrations of aflatoxins were spiked in water and irradiated at UV-A doses ranging from 0 to 1,200 mJ/cm2. The concentration of AFB1 and AFM1 was determined by HPLC with fluorescence detection. LC–MS/MS …

Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson

Physiology Faculty Publications

In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the identification of novel areas for therapeutic and scientific exploitation. Here, we review the organizational and activational effects of sex hormones on recovery from injury and how these changes impact the long-term health of spinal cord injury (SCI) patients. When determining how sex affects SCI it remains imperative to expand outcomes beyond locomotor recovery and consider other complications plaguing the quality of …

Lingnan Gardeners Bimonthly Newsletter (No. 50) = 嶺南彩園通訊 (第50期), Lingnan Gardeners, Kwan Fong Cultural Research And Development Programme, Lingnan University

Lingnan Gardeners Newsletter 嶺南彩園通訊

Climber 藤三七

Anthropogenic Drivers And Ecological Concepts Of Antimicrobial Resistance, Rachelle E. Beattie

Dissertations (1934 -)

Antimicrobial resistance (AMR) is a ubiquitous global health issue driven by the overuse and misuse of antimicrobial compounds in healthcare and veterinary medicine. Both natural and built environments have been recognized as reservoirs of antimicrobial resistant bacteria, genes, and pathogens but the factors that drive increases in their abundance are not well understood, especially in natural environments. The primary goal of this work is to characterize the ecological drivers of antimicrobial resistance in freshwater ecosystems impacted by intensive livestock farms, known contributors of environmental resistance. Kewaunee County, Wisconsin served as an ideal study site for the investigation of the impact …

Repression Of Tick Microrna-133 Induces Organic Anion Transporting Polypeptide Expression Critical For Anaplasma Phagocytophilumsurvival In The Vector And Transmission To The Vertebrate Host, Ellango Ramasamy, Vikas Taank, John F. Anderson, Hameeda Sultana, Girish Neelakanta

Biological Sciences Faculty Publications

The microRNAs (miRNAs) are important regulators of gene expression. In this study, we provide evidence for the first time to show that rickettsial pathogen Anaplasma phagocytophilum infection results in the down-regulation of tick microRNA-133 (miR-133), to induce Ixodes scapularis organic anion transporting polypeptide (isoatp4056) gene expression critical for this bacterial survival in the vector and for its transmission to the vertebrate host. Transfection studies with recombinant constructs containing transcriptional fusions confirmed binding of miR-133 to isoatp4056 mRNA. Treatment with miR-133 inhibitor resulted in increased bacterial burden and isoatp4056 expression in ticks and tick cells. In contrast, treatment with …

Consumer Food Socialization In The School And Home, Ashley Deutsch Cermin

Graduate Theses and Dissertations

Consumer socialization literature has focused on individual socialization agents and their isolated effects. However, as John (1999) pointed out, children do not grow up in a social vacuum. Instead, the multitude of agents socializing children find their narratives interacting and their effects continually shaped and co-created. To understand how school-age children learn about food, I interrogate the complexity of socialization in three essays.

In the first essay, I take an ethnographic approach to investigate the interactive effect peers and adults, namely service workers, have on children’s food socialization in a public-school lunchroom. By combining a Loseke’s (2007) layered narrative model …

Are We Producing Society-Ready Foresters? A Quantitative Content Analysis Of Graduate-Level Forestry Curriculum, Jacqueline Meyer

The Pegasus Review: UCF Undergraduate Research Journal

Forestry education in the United States has been hailed for its ability to provide students with the scientific and technical skills needed for a career in forestry as much as it has been criticized for ignoring social dimensions of the discipline. Its inability to adapt curriculum to the increasingly multidisciplinary nature of the forestry profession has led to stagnant or decreasing enrollment and lack of student diversity in recent years. While forestry education and curriculum has been thoroughly analyzed at the undergraduate level, no such analysis exists for graduate curriculum. This study analyzes the course content of 40 graduate-level forestry …

Photic Stress On Coral Reefs In The Maldives: The Amphistegina Bleaching Index, Stephanie Stainbank, Silvia Spezzaferri, Valentina Beccari, Pamela Hallock, Arthur Adams, Auriele Angeloz, Daniela Basso, Annalisa Caragnano, Nicolo Del Piero, Patrick Dietsche

Marine Science Faculty Publications

The Amphistegina Bleaching Index (ABI) was applied to three Maldivian reefs in the Rasdhoo and North Ari Atolls in 2018, during normal sea surface temperature conditions. This dataset was then compared with a 2015, pre-coral bleaching study. The results provide a context for the verification and application of the ABI in outlining the photo-inhibitory stress status of coral reefs outside of the Florida Reef Tract where it was originally developed. The sampling periods encompass different seasons and temperature regimes. The 2015 field sampling preceeded the El Niño induced, mass coral-bleaching events of 2015 and 2016. It was carried out in …

Life Of Tau: Oligomerization, Cns Extracellular Clearance And Role As Plasma Biomarker, Tirth Patel

Arts & Sciences Graduate Student Theses and Dissertations

The microtubule associated protein tau (MAPT, commonly referred to as tau) is an intrinsically disordered, highly soluble protein predominantly expressed in axons where it binds and stabilizes microtubules. Under normal physiological conditions, soluble monomeric tau is released in the extracellular space in the interstitial fluid (ISF) by neurons. Additionally it undergoes reversible phosphorylation and other extensive modifications inside the cell under the action of a host of enzymes. However in the disease process tau loses this solubility, detaches from microtubules and ultimately migrates to the somatodendritic compartment of the neuron, where it ultimately forms insoluble fibrillar aggregates known as tau …

The Butler-Tarkington Community Member Views On The Perceived Gentrification, Julio C. Trujillo, Jr., Ethan Daniels

Butler Journal of Undergraduate Research

No abstract provided.

The Role Of Cell Division During Tissue Morphogenesis, Lindsay Rathbun

Dissertations - ALL

During embryonic tissue morphogenesis, cell division increases both the number of cells and cellular diversity. This is often regulated by the positioning of daughter cells post-mitosis. The goal of this dissertation research is to determine the mechanisms that place daughter cells, and how this contributes to tissue development. First, the zebrafish left-right organizer, Kupffer’s vesicle (KV) is used as a model to investigate the role of cytokinesis and abscission during de novo lumen formation. The cytokinetic bridge places at the center of the developing KV rosette, where it acts as a landmark for Rab11-mediated vesicle trafficking to bring polarity components …

Using Bioinformatics Tools To Evaluate Potential Risks Of Food Allergy And To Predict Microbiome Functionality, Mohamed Abdelmoteleb

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Novel foods and Genetically Engineered (GE) organisms are being developed for nutritional, industrial, and environmental applications. Dietary interventions have been used recently to mitigate methane emissions in ruminants. In this project, bioinformatics tools have been used to answer two main questions. The first question is the potential allergy risks for consumption of novel foods and GE organisms. The second question is the effects of dietary interventions on microbiome functionality related to methane production in ruminants.

To answer the first question, regulatory authorities in the United States and Europe now expect an evaluation of new proteins in novel foods or genetically …

Lingnan Gardeners Bimonthly Newsletter (No. 49) = 嶺南彩園通訊 (第49期), Lingnan Gardeners, Kwan Fong Cultural Research And Development Programme, Lingnan University

Lingnan Gardeners Newsletter 嶺南彩園通訊

Noble Dendrobium Stem Herb 石斛花

Assessment Of The Toxicological Effects Of Cnt-Ab In Mice Followed By Microwave Hyperthermia 14 Days Post Treatment., Andrew C. Mixson

Honors College Theses

Serious side effects and treatment resistance are the main impediments to successful cancer therapy. A variety of nanoparticles have been used for localized, site-specific treatment that prevent or circumvent these impediments. Microwaves alone have been previously used for thermal ablation of various tumors, setting precedence for their successful use in live organisms. In cell culture studies, it has been observed that multiwall carbon nanotubes (MWCNTs) instantly and efficiently absorb microwaves, causing hyperthermia of cells in direct contact with them with unnoticed harm to other cells. It is hypothesized that a treatment can be developed based on a safe microwave heating …

Time Specific Population Dynamics Of Diatoms In Artificial Environments, Sydney Brown

Georgia College Student Research Events

Algae serve as the base trophic level of aquatic systems, energetically supporting entire aquatic communities. Culturing in a laboratory setting requires significant phycological background and ecological knowledge to mimic their natural environmental conditions. The purpose of this research was to explore the effects of time on the growth of algal cultures. Gomphonema parvulum was the species investigated, falling into a class of algae known as diatoms- which are defined by cell walls composed of silica. Due to this unique morphological feature, asexual reproduction results in a diminution of cell size each generation in which restoration of natural sizes is initiated …

Alimentando A México: Los Movimientos Indígenas Y Agrícolas Contra Las Políticas Neoliberales, Sofia Buchler

Independent Study Project (ISP) Collection

Para analizar la complejidad de la agricultura en México en este momento, es necesario analizar las políticas neoliberales de México. El Tratado de Libre Comercio de América del Norte (TLCAN) marca un punto de inflexión para la privatización de las tierras agrícolas y los cambios de la dieta mexicana. Las políticas de los últimos cuarenta años han destruido la dieta de la milpa en México y la tradición del policultivo. Los cambios en la agricultura han destruido el suelo, y forzado a los pequeños agricultores a abandonar sus tierras y buscar trabajos diferentes. Hay una gran historia de resistencia indígena …

Postprandial Microvascular Blood Flow In Skeletal Muscle: Similarities And Disparities To The Hyperinsulinaemic-Euglycaemic Clamp, Katherine M. Roberts-Thomson, Andrew C. Betik, Dino Premilovac, Stephen Rattigan, Stephen M. Richards, Renee M. Ross, Ryan D. Russell, Gunveen Kaur, Lewan Parker, Michelle A. Keske

Health & Human Performance Faculty Publications

Skeletal muscle contributes to ~40% of total body mass and has numerous important mechanical and metabolic roles in the body. Skeletal muscle is a major site for glucose disposal following a meal. Consequently, skeletal muscle plays an important role in postprandial blood glucose homeostasis. Over the past number of decades, research has demonstrated that insulin has an important role in vasodilating the vasculature in skeletal muscle in response to an insulin infusion (hyperinsulinaemic-euglycaemic clamp) or following the ingestion of a meal. This vascular action of insulin is pivotal for glucose disposal in skeletal muscle, as insulin-stimulated vasodilation increases the delivery …

Role Of Bet Inhibitors In Triple Negative Breast Cancers, Durga Khandekar, Venkataswarup Tiriveedhi

Biology Faculty Research

Bromodomain and extraterminal domain (BET) proteins have evolved as key multifunctional super-regulators that control gene expression. These proteins have been shown to upregulate transcriptional machinery leading to over expression of genes involved in cell proliferation and carcinogenesis. Based on favorable preclinical evidence of BET inhibitors in various cancer models; currently, 26 clinical trials are underway in various stages of study on various hematological and solid organ cancers. Unfortunately, preliminary evidence for these clinical studies does not support the application of BET inhibitors as monotherapy in cancer treatment. Furthermore, the combinatorial efficiency of BET inhibitors with other chemo-and immunotherapeutic agents remain …

Beauty For Ashes: Reflections On Aesthetic Experience And Suffering, Douglas Gilmour

Verbum Incarnatum: An Academic Journal of Social Justice

In this essay, I examine the relationship between aesthetic experience and suffering, and I specifically explore how and why the former can potentially serve to meliorate the severity of the latter. Of course, that art and beauty can provide a certain measure of comfort and healing to the afflicted is a universally acknowledged truth; however, the reasons why this should be so could be considered an equally universal mystery. “I feel we understand too little about the psychology of loss,” writes Arthur Danto, “to understand why the creation of beauty is so fitting a way of marking it.” By exploring …

Music Therapy As A Treatment For Female Adolescents With Childhood Abuse, Janice M. Dvorkin Psy.D, Acmt, Sierra Belmares

Verbum Incarnatum: An Academic Journal of Social Justice

This article describes the preference to using receptive music therapy as a modality for helping an adolescent who has PTSD from childhood abuses. Adolescence is a difficult period during the life span. The second stage of separation/individuation provides challenges to almost all adolescents. This article contains a description of the adolescent behaviors of someone who is experiencing the consequences of PTSD. Along with an explanation of why receptive music therapy is an effective therapy with this population is a case study.

Suicide And Culture, Mehmet Eskin

BAU Journal - Health and Wellbeing

The rates of suicidal ideation, attempts and mortality present a large intersocietal variation. This variation is usually attributed to the role of culture, but the issue is still poorly understood. How does culture contribute to the intersocietal or cross-cultural variation of suicidal behavior? How culture might be involved in the onset, maintenance and aggravation of suicidal tendencies? In this paper, I will be discussing possible mechanisms of culture for the onset, maintenance and aggravation of suicidal propensities. Specifically, I will be examining the role of religion, individualistic-collectivistic value orientations, self-construal and survival versus self-expression values for their relevance to suicidal …

The Employment Of A Conformal Polydopamine Thin Layer Reduces The Cytotoxicity Ofsilver Nanoparticles, Asli Yilmaz

Turkish Journal of Zoology

Silver nanoparticles (AgNPs) with their unique properties represent great promise in biological applications. However, the high toxicity of AgNPs still remains a major bottleneck and hinders their basic usage. In the present study, to improve the cytotoxicity of AgNPs, a thin layer of polydopamine (PDOP) was proposed as shell material. For this, the as-prepared citrate-stabilized AgNPs were dispersed in dopamine solution under alkaline conditions. The thickness of the PDOP layer could be manipulated simply by tuning the polymerization time. It was indicated that all NP systems (PDOP, AgNP, and AgNP@PDOP) were efficiently synthesized in the desired size and morphology. Cytotoxicity …

X Chromosome Dosage Of Histone Demethylase Kdm5c Determines Sex Differences In Adiposity, Jenny C. Link, Carrie B. Wiese, Xuqi Chen, Rozeta Avetisyan, Emilio Ronquillo, Feiyang Ma, Xiuqing Guo, Jie Yao, Matthew Allison, Yii-Der Ida Chen, Jeremy I. Rotter

Biology

Males and females differ in body composition and fat distribution. Using a mouse model that segregates gonadal sex (ovaries and testes) from chromosomal sex (XX and XY), we showed that XX chromosome complement in combination with a high-fat diet led to enhanced weight gain in the presence of male or female gonads. We identified the genomic dosage of Kdm5c, an X chromosome gene that escapes X chromosome inactivation, as a determinant of the X chromosome effect on adiposity. Modulating Kdm5c gene dosage in XX female mice to levels that are normally present in males resulted in reduced body weight, fat …

Southern California Margin Benthic Foraminiferal Assemblages Record Recent Centennial-Scale Changes In Oxygen Minimum Zone, Hannah M. Palmer, Tessa M. Hill, Peter D. Roopnarine, Sarah E. Myhre, Kastherine R. Reyes, Jonas T. Donnenfield

Natural Sciences and Mathematics | Student Professional Publications

Microfossil assemblages provide valuable records to investigate variability in continental margin biogeochemical cycles, including dynamics of the oxygen minimum zone (OMZ). Analyses of modern assemblages across environmental gradients are necessary to understand relationships between assemblage characteristics and environmental factors. Five cores were analyzed from the San Diego margin (32∘42′00′′ N, 117∘30′00′′ W; 300–1175 m water depth) for core top benthic foraminiferal assemblages to understand relationships between community assemblages and spatial hydrographic gradients as well as for down-core benthic foraminiferal assemblages to identify changes in the OMZ through time. Comparisons of benthic foraminiferal assemblages from two size fractions (63–150 and >150 …