Digital Commons Network^™

The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery

Faculty, Staff and Student Publications

Not available.

Rna Sequencing-Based Transcriptome Analysis Of Liver In Laying Hens Supplemented With Dietary Probiotic Bacillus Species And Prebiotic Yeast (Saccharomyces Cerevisiae) Cell Walls, Ala E. Abudabos, Zafar M. Hakami, Ali R. Al Sulaiman, Riyadh S. Aljumaah, Valentino Palombo, Mashael R. Aljumaah, Mariasilvia D’Andrea, Abdulrahman S. Alharthi, Rashed A. Alhotan

Food and Animal Sciences Faculty Research

To investigate the impacts of dietary Bacillus-based probiotics and yeast-derived prebiotics on the hepatic transcriptome profile, 500 Hisex White laying hens were randomly allotted into five dietary treatments from 37 to 52 weeks of age: control; control + Bacillus subtilis; control + Bacillus subtilis and Bacillus licheniformis; control + Bacillus coagulans; and control + Saccharomyces cerevisiae yeast cell wall. Transcriptome analysis revealed a substantial number of differentially expressed genes exclusively between the control and prebiotic groups, identifying 2221 genes (FDR ≤ 0.05), with 980 genes upregulated (log2 fold change 0.69 to 24.62) and 1241 downregulated (log2 fold change −0.74 to …

Mollusks From Crusader-Period ‘Akko, The Knights’ Hotel Site, Inbar Ktalav

'Atiqot

This study analyzes mollusk remains collected during the 2007 excavation season at the Knights’ Hotel site in ‘Akko, which was part of a Crusader-period residential neighborhood. A total of 538 shells were identified, including marine shells from the Mediterranean and Red Seas, freshwater shells and land snails. The analysis of these shells sheds light on the lives of the Crusader-period residents of ‘Akko, including their trade connections and use of shells for construction, ornamentation, pigment containers and raw material for the inlay industry.

The Jewish Chalk-Vessel Industry In Galilee And The Golan, Yonatan Adler

'Atiqot

This study explores archaeological remains of the Jewish chalk-vessel industry in Galilee and the Golan during the Early Roman period. It examines recent excavations at ‘Einot Amitai, Reina and Lower Wadi es-Sufera, focusing on raw materials, manufacturing techniques and typologies of vessels produced at these sites. The study also looks at the chronology of this industry, exploring when chalk-vessel production in the north first began and when it ended. Throughout the paper, the archaeological remains from the northern sites are compared and contrasted with findings from Jerusalem-area workshops. Finally, the study investigates what the archaeological remains analyzed here may indicate …

Researching Chalcolithic Ivories From The Southern Levant: Craft Items For Ritual, Prestige And Exchange, Harel Shochat, Liora Kolska Horwitz, Avishay Levi-Hevroni, Martin D. Pasternak, Pablo Betzer, Daniel Varga, Yael Abadi-Reiss, Olga Negnevitsky, Ilan Naor, Ianir Milevski

'Atiqot

The Late Chalcolithic period in the Southern Levant, mainly the Ghassulian culture (mid-fifth–mid-fourth millennia BCE), heralded a new and unique trajectory in craft specialization, with ivory objects, including figurines, tools and vessels, among the outstanding ones. Hippopotamus and elephant ivory, probably of varied geographic provenience, were the raw materials employed. This paper presents two recently excavated ivory caches from the Late Chalcolithic sites of Ḥorbat Raqiq and Yavne (East), and reviews Chalcolithic ivories from this region. Additionally, a systematic microscopic analysis to determine the taxonomic identification of raw material and typological classification of each artifact is presented, offering novel perspectives …

Data For Recreation Effects On Soil Carbon, Biocrust, Soil Stability, And Invasives In Indian Creek, Bears Ears National Monument, Elisabeth M. Currit, Tara B. Bishop, April Hulet, Nathan Allen Currit, Teresa Gomez, Nathan T. Thompson, Shannon Lambson, Heidi Jean Wilding Mann, Evan Miller, Erin Jones, Alexandra Olson, Katherine A. Anselmi, Meredith Murdock, Ella Reid, Kirsten Steele, Indy Lawrence, Neil Hansen

ScholarsArchive Data

This data is about how different types of recreation impact different soil and vegetation properties related to soil carbon in Indian Creek, Bears Ears National Monument. The data was collected from May 2023 to October 2023. It contains plant functional group cover, biocrust cover and type, soil stability, and compaction data for each individual site. There are 5-7 of each site type: camping, foot trails, and motorized offroading trails, and undisturbed sites, with a total of 30 sites. It also contains the code used to analyze the raw data and the figures created.

Suppression Of Cardiac Allograft Vasculopathy By A Macrophage Efferocytosis Receptor, Sahil Shah, Aparnaa Ananthakrishnan, Matthew Deberge, Kristofor Glinton, Rebecca T L Jones, Mallory Filipp, Ivana Shen, Joey Lockhart, Connor W Lantz, Edward B Thorp

Faculty, Staff and Student Publications

Cardiac allograft vasculopathy remains a major cause of late morbidity following heart transplantation. While accumulating evidence implicates innate macrophages in the inflammatory progression of CAV, the underlying mechanisms remain incompletely understood. In murine models of CAV, we identified proteolytic cleavage of MERTK, a key anti-inflammatory receptor on macrophages, as a contributing factor to CAV progression. In a model of CAV, MERTK deficiency accelerated allograft rejection and increased intimal leukocyte infiltration. In contrast, mice expressing a genetically cleavage-resistant form of MERTK (MertkCR/CR) exhibited prolonged graft survival, reduced intimal thickening, diminished immune cell infiltration, and decreased circulating effector T cells. …

Reproducibility Of Statistically Significant Phase Iii Oncology Trials: An In Silico Meta-Epidemiological Analysis, Alexander D Sherry, Pavlos Msaouel, Avital M Miller, Timothy A Lin, Joseph Abi Jaoude, Ramez Kouzy, Adina H Passy, Tomer Meirson, Nikolaos Ignatiadis, Zachary R Mccaw, Erik Van Zwet, Ethan B Ludmir

Faculty, Staff and Student Publications

Purpose: The conventional assumption that P values ≤ 0.05 imply reproducible effects has come under recent criticism. This concern is particularly relevant in oncology, as phase III oncology trials, which directly inform practice, are usually not repeated. Using advanced modeling techniques, we investigated the relationship between P values and reproducibility in oncology.

Methods: We obtained the signal-to-noise ratio distribution in phase III oncology using outcomes from 632 two-arm superiority trials enrolling 496,219 patients. With this distribution, we estimated successful replication probability as the probability that a replicate trial, having the same design, effect size, and standard error, would have a …

Artificial Intelligence In Ocular Transcriptomics: Applications Of Unsupervised And Supervised Learning, Catherine Lalman, Yimin Yang, Janice L. Walker

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Transcriptomic profiling is a powerful tool for dissecting the cellular and molecular complexity of ocular tissues, providing insights into retinal development, corneal disease, macular degeneration, and glaucoma. With the expansion of microarray, bulk RNA sequencing (RNA-seq), and single-cell RNA-seq technologies, artificial intelligence (AI) has emerged as a key strategy for analyzing high-dimensional gene expression data. This review synthesizes AI-enabled transcriptomic studies in ophthalmology from 2019 to 2025, highlighting how supervised and unsupervised machine learning (ML) methods have advanced biomarker discovery, cell type classification, and eye development and ocular disease modeling. Here, we discuss unsupervised techniques, such as principal component analysis …

Effects Of Cryoprotective And Mitochondrial Stabilizing Agents On Vitrified Bovine Oocytes, Allison Hoang

LSU Master's Theses

Oocyte vitrification success is highly dependent on cryoprotectant agent (CPA) choice as well as possible additives that could help preserve mitochondrial membrane potential (mMP), reactive oxygen species (ROS) production, and calcium homeostasis within the cell. It is a delicate balance between levels needed for proper oocyte function and activation and levels needed to induce apoptotic pathways. The results of oocyte cryopreservation determine the eventual oocyte viability and subsequent fertilization and embryo development.

In this study potential permeating cryoprotectant combinations were explored such as ethylene glycol (EG) and propylene glycol (PG) or EG in combination with dimethyl sulfoxide (DMSO). Also, the …

16-Week Physical Transition From Professional Mma To Tactical Firefighting: A Case Study, Cole D. Smeester, Gabriel J. Sanders, Corey Peacock, Jose Antonio

Journal for Sports Neuroscience

Firefighters, whose occupation involves intense physical, mental, and environmental demands, must be physically and mentally prepared to perform job-specific tasks effectively and safely. Nearly half of all injuries sustained on and off the fireground are musculoskeletal, highlighting issues in the preparation and maintenance strategies for work preparedness among firefighters. This case study examines the effectiveness of a 16-week conventional, conjugate strength and conditioning model on a fire recruit transitioning from a career as a professional MMA fighter. Specific data metrics were used to assess increases in firefighter-specific performance (i.e., EPAT time and body composition). After the 16-week program, the participant …

Idmatch Bike Fitting Enhances Power Output In Recreational Cyclists: A Pilot Study, Evan T. Hoyt, Gregory N. Ruegsegger

International Journal of Exercise Science

International Journal of Exercise Science 18(2): 864-880, 2025. Optimizing bike position is essential for enhancing cycling performance, improving comfort, and reducing injury risk. This study examined the acute effects of a bike fit using the idmatch^® system on power output, rate of perceived exertion (RPE), and discomfort in recreational cyclists. Twelve participants (10 males, 2 females; 37.0 ± 9.4 years) underwent an idmatch system bike fit, which employs three-dimensional motion capture to optimize rider position. Cyclists completed a six-second peak power test (PPT6) and a 20-minute functional threshold power (FTP) test before and after the fit. Performance metrics (power, …

Identification, Abundance, And Behavior Of North American Bobcat (Lynx Rufus) Along Road Mitigation Structures Designed For Endangered Species In South Texas, Victoria Hanley, Kevin W. Ryer, Md. Saydur Rahman, John H. Young Jr., Richard J. Kline

School of Integrative Biological & Chemical Sciences Faculty Publications

Endangered species are increasingly used as the target species in implementing and constructing new wildlife crossing structures (WCS). Highways in South Texas fragment the landscape and result in high road mortality for endangered species such as ocelots (Leopardus pardalis, a medium-sized spotted wild cat). In response, the Texas Department of Transportation constructed nine WCS on Farm-to-Market 106 (FM 106), a road which bisects Laguna Atascosa National Wildlife Refuge in Cameron County, Texas. With ocelots being rare and elusive, bobcats (Lynx rufus) are often used as a surrogate species to study felid behavior at road mitigation structures …

A Comparison Of Diving Behavior Of Goose-Beaked And Dense-Beaked Whales From Tagging Studies In Multiple Ocean Basins, Jay Barlow, Robin W. Baird, Janelle Badger, Gregory S. Schorr, Erin A. Falcone, Shannon N. Coates, Peter L. Tyack, Andrew J. Read, Leigh S. Hickmott, John W. Durban, Diane Claridge, Natacha Aguilar De Soto, Daniel Miranda Gonzalez, Fleur Visser, Machiel G. Oudejans, Stacy L. De Ruiter, David A. Sweeney, Brenda K. Rone, Stephanie L. Watwood

University Faculty Publications and Creative Works

Studies of cetacean diving behavior in multiple locations in different ocean basins allow for an assessment of variability within and among populations. We examine foraging dive behaviors of goose-beaked whales (Ziphius cavirostris) and dense-beaked whales (Mesoplodon densirostris) using data from 132 tagged whales in seven locations in the Pacific and Atlantic Oceans and the Mediterranean Sea. Acoustic recording tags are used to identify foraging dives by the presence of echolocation. For other tag types, foraging dives are identified based on maximum dive depth. Five parameters are used to characterize foraging dives: maximum dive depth, foraging dive duration, dive cycle duration, …

Crossroads Of Covid-19 And Alzheimer’S: Investigating Sars-Cov-2 Nsp6 And Orf7a In Amyloid-Β42 Toxicity, Jeffrey William Huettemann, Amit Singh

Research from the Berry Summer Thesis Institute, 2025

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in several hundred million contracted cases of coronavirus disease 2019 (COVID-19) and a global pandemic. In some of these cases, previous neurological diseases, such as Alzheimer’s disease (AD), seemed to progress much more rapidly after the COVID-19 infection. Thus, we became interested in studying the effects of SARS-CoV-2 infection on prior neurological disease progressions.

To modulate this condition, we used Drosophila melanogaster as a genetic model system. We had previously developed the Alzheimer’s Disease Fly Model with expression of human amyloid beta 42 (Aβ42) peptide, which is responsible for extracellular Aβ-42 …

An Investigation Of Hydro-Morphological Changes At The Estuarine Outlet Of Kitchener Drain, Northern Coast Of Egypt, Nada Mansour, Karim Nassar, Mahmoud El-Gamal, Tharwat Sarhan

Mansoura Engineering Journal

In recent years, sedimentation and coastline erosion have occurred in the Kitchener Drain, where its outflow meets the Mediterranean Sea. Several measures have been taken to mitigate the impact of these problems. Excavation continues toward the drain's outlet, and there have been multiple stages of hard protection work, such as groins along the drain's eastern and western banks. What would happen if the working near the drain was kept, where accretion and erosion are most severe. The Coastal Modelling System (CMS) was used to find it out. The two-dimensional hydrodynamic circulation model known as the CMS is outfitted with modules …

Performance Analysis Of Computational Methods For Predicting Protein Function In Rare Diseases, Aichetou Mohamed Sidiya, Hanin Alzaher, Razan Almahdi, Tayeb Brahimi

Effat Undergraduate Research Journal

Protein function prediction is crucial for understanding the underlying mechanisms of rare diseases. With the increasing availability of computational methods including machine learning-based approaches, network-based methods, and sequence-based methods, predicting protein functions has become more accessible. However, it is not clear which of these methods performs better or how they compare to each other in terms of accuracy, efficiency, and scalability. In this study, we evaluate several computational methods for predicting protein functions in rare diseases using key performance indicators (KPIs). We analyze the strengths and weaknesses of each method and provide recommendations for researchers and clinicians interested in using …

The Effects Of Exercise Training In A Novel Full-Body Compression Garment On Anaerobic Performance In Healthy Men, Benjamin W. Cunningham, Mikayla M. Reese, Jesse M. Jansen, Benjamin S. Minier, Curtis A. Cornell, Faith C. Benedict, Joshua T. Mayne, Justin A. O'Dell, Gabriel M. Lysak, James R. Sackett

International Journal of Exercise Science

International Journal of Exercise Science 18(8): 836-851, 2025. Although acutely donning compression garments improves several markers of athletic performance, the effects of training in compression garments remains largely unexplored. Thus, this study aimed to determine the effects of exercise training while donning a novel full-body compression garment on multiple measures of anaerobic performance. Sixteen sedentary males (age: 21±3 y; BMI: 25±3 kg/m²) completed 4 weeks of training with (CG; n=8) or without (CON; n=8) a novel full-body compression garment. Subjects performed a 40m sprint (time and velocity), a 5-repetition maximum barbell back squat (barbell weight and serratus anterior …

Advancing Rfid Systems: From Head Orientation To Robotic Localization Using Passive Tags, Guilherme Ricardo Mendes Da Silva Barreto De Figueiredo

Doctoral Dissertations

No abstract provided.

Role Of Nucleic Acids As Chaperones In Protein Folding, Zijue Huang

Electronic Theses and Dissertations

Many proteins have slow folding times in vitro that are physiologically untenable. To combat this challenge, ATP-dependent chaperonins are thought to possess the unique ability to catalyze protein folding. Performing quantitative model selection using protein folding and unfolding data, we here show that short nucleic acids containing Gquadruplex (G4) structure can also catalyze protein folding. Performing the experiments as a function of temperature demonstrates that the G4 reshapes the underlying driving forces of protein folding. To understand the structural basis of this catalytic activity, we introduce NMR method to solve the structures, at base-level resolution, of a multiconformer G4 with …

Predicting Regional Cerebral Blood Flow Using Voxel-Wise Resting-State Functional Mri, Hongjie Ke, Bhim M Adhikari, Yezhi Pan, David B Keator, Daniel Amen, Si Gao, Yizhou Ma, Paul M Thompson, Neda Jahanshad, Jessica A Turner, Theo G M Van Erp, Mohammed R Milad, Jair C Soares, Vince D Calhoun, Juergen Dukart, L Elliot Hong, Tianzhou Ma, Peter Kochunov

Faculty, Staff and Student Publications

Background: Regional cerebral blood flow (rCBF) is a putative biomarker for neuropsychiatric disorders, including major depressive disorder (MDD).

Methods: Here, we show that rCBF can be predicted from resting-state functional MRI (rsfMRI) at the voxel level while correcting for partial volume averaging (PVA) artifacts. Cortical patterns of MDD-related CBF differences decoded from rsfMRI using a PVA-corrected approach showed excellent agreement with CBF measured using single-photon emission computed tomography (SPECT) and arterial spin labeling (ASL). A support vector machine algorithm was trained to decode cortical voxel-wise CBF from temporal and power-spectral features of voxel-level rsfMRI time series while accounting for PVA. …

Enhancing Cataract Surgery Outcomes: Optimal Use Of Pre- And Post-Operative Eye Drops, Keith Skolnick M.D., Anu Valiaveedu

Mako: NSU Undergraduate Student Journal

Many preoperative and postoperative cataract patients struggle with comprehending the use of prescription medication as directed. Language barriers and low health literacy levels are major factors contributing to improper use of prescriptions. To increase patients comprehension, the Fort Lauderdale Eye Institute employed an educational intervention consisting of a live presentation and an instructional video. Results found that 44% of patients were hesitant to ask questions to clinical staff, 32% felt overwhelmed, and nearly 70% lacked confidence in using their prescribed eye drops. Following the intervention, 91% of patients reported increased confidence in their medications, and most indicated that the video …

Innovative Approaches To Estimating Sessile Oak Stem Volume: Comparing Additive Models And Ensemble Machine Learning, Maria J. Diamantopoulou, Abbas Şahi̇n, Ramazan Özçeli̇k

Turkish Journal of Agriculture and Forestry

Sessile oak is an important deciduous forest tree species across Türkiye and Europe. Estimating individual tree and stand volumes is essential for growth and yield models, as these predictions play a critical role in assessing forest management, economics, and fire risk. In pursuit of this goal, nonlinear seemingly unrelated regression (NSUR) was used for the simultaneous fitting of stem volume components, and compared to three ensemble machine learning techniques: gradient boosting regression (GBr), XGBoost regression (XGBr), and random forest regression (RFr). NSUR accounts for correlations between error terms across different equations, leading to more efficient parameter estimates than if each …

Monitoring The Developmental Stages Of Calendula Officinalis L. Nutrients Efficacy Under Hot Weather Mitigation Through Nutrients In Haripur, Pakistan, Waseem Ahmed, Rafia Azmat, Shah Masaud Khan, Abdul Qayyum, Waseem Hassan, Adnan Noor Shah, Muhammad Hadi Abbas, Fatima M. Abbas, Tahani A.Y. Asseri, Ahmet Hakan Ürüşan

Turkish Journal of Agriculture and Forestry

This study examines the effect of different doses of N and P fertilizer on Calendula officinalis L. (marigold) during the hot weather in summer (May–July) in Pakistan. The aim was to determine whether fertilization can help minimize the impacts of climate change. During the summer peak seasons (May, June, and July), the trial was conducted in potted plants with different N and P application levels to monitor the quality and quantity of C. officinalis. The results showed that the interactive effects (N × P) gave higher values for plant height, number of leaves, fresh weight, leaf length, and number of …

Muscarinic Acetylcholine Receptor 1: Implications For Precision Medicine And Rett Syndrome Therapeutics, Mackenzie Smith

Dissertations

Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by mutations in the gene coding for methyl-CpG binding protein 2 (MeCP2). Currently, there is no cure for RTT and few effective treatment options to address the social, cognitive, motor, and respiratory symptoms that patients face. With the goal of identifying novel targets, our lab performed RNA-sequencing experiments in human autopsy samples and found decreased levels of the M1 muscarinic acetylcholine receptor. We have established that potentiation of this receptor in a Mecp2+/- mouse model of RTT rescues social, cognitive, and respiratory phenotypes, providing support for using drugs that act on …

Wbd-Yolo-Am: Yolov8 With Attention Module And Iot-Based Wild Boar Detection And Deterrence System For Safeguarding Small Millets, Aditya Joshi, Neha Pandey, Manoj Diwakar, Prabhishek Singh, Achyut Shankar, Fayez Alqahtani

Turkish Journal of Agriculture and Forestry

Small millets are traditional and climate-resilient food crops that can grow in adverse weather conditions. Animal intrusion, specifically from wild boars, is a main threat to the production of small millets, which reduces interest in the cultivation of small millets and affects farmers’ incomes. To address the problem of wild boar attack on agriculture land, an improved YOLOv8 is proposed, with an attention module based on WBD-YOLO-AM and that works from the collection of data, its preprocessing, attention mechanism to improve the feature maps, training then building the model, after that the models hyperparameter are tuned to boost the performance …

Assessment Of Bat Species (Mammalia: Chiroptera) In Canubas Cave, Kibawe, Bukidnon, Philippines, Jurriel Mari D. Alce, Jasmine Rouida M. Abenes, Leo Gabriel Cervantes, Matthew Eli K. Llacer, Von Zhyrus P. Oche, Ian Jay P. Saldo, Jhovel Roy D. Calo

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Bats, flying mammals, are essential to ecosystems, playing vital roles in pollination, seed dispersal, and insect control. Despite their ecological importance, no prior bat research exists for Canubas Cave, Kibawe, Bukidnon. This study aimed to assess the bat species at the site, documenting their morphometric data, diversity and richness indices, and conservation statuses. A purposive sampling design was implemented by setting up mist nets inside and outside the cave. A total of 13 individuals were identified, comprising three species from two families: Rousettus amplexicaudatus and Eonycteris spelaea (family Pteropodidae, fruit bats), and Miniopterus schreibersii (family Miniopteridae, bent-winged bats). Based on …

A Multimodal Approach To Assess A Liposomal Carrier’S Biodistribution, Stability, And Clearance, Cayla A Wood, Claire E Jones, Ananthakrishnan Soundaram Jeevarathinam, Riley Watson, Sangheon Han, Jennifer Meyer, Konstantin V Sokolov, Richard R Bouchard

Faculty, Staff and Student Publications

Liposomal carriers, used for site-specific drug delivery, are being investigated for diagnostic approaches by replacing the therapeutic with an imaging contrast agent, exploring potential for selective treatment planning. There remains a critical need to improve in vivo assessment of biodistribution, stability, and clearance kinetics of liposomal carriers. This pilot study presents a multimodal approach in which liposome-encapsulated J-aggregated indocyanine green (ICG) dye (Lipo-JICG) is imaged with high spatial resolution using both in vivo photoacoustic (PA) imaging, to assess the absorbance characteristics of JICG and monomeric ICG, and ex vivo cryofluorescence tomography (CFT), to measure ICG fluorescence. An in vitro assay …

Statistical Analysis Of Multi-Endpoint Phenotypic Screening Increases Sensitivity Of Planarian Neurotoxicity Testing, Danielle Ireland, L. J. Word, Eva-Maria S. Collins

Biology Faculty Works

There is an urgent need for high-throughput screening (HTS) models to replace, refine, and/or reduce (“3Rs”) vertebrate toxicity testing. Replacing in vivo animal studies is challenging for neurotoxicity and developmental neurotoxicity (DNT), where the functional relevancy of adverse outcomes needs to be assessed on the whole organism. We previously screened the NTP 87-compound library (NTP87), consisting of known and suspected developmental neurotoxicants, and showed that planarian HTS can identify known (developmental) neurotoxicants. Because analysis methods can impact screening results, and our original analysis used the lowest-observed-effect-level (LOEL) only, we hypothesized that the use of state-of-the-art statistical analysis would increase the …

Tracing Priming Effects In Palsa Peat Carbon Dynamics Using A Stable Isotope-Assisted Metabolomics Approach, Christian Ayala-Ortiz, Moira Hough, Elizabeth K. Eder, David W. Hoyt, Rosalie K. Chu, Jason Toyoda, Steven J. Blazewicz, Patrick M. Crill, Ruth Varner, Scott R. Saleska, Virginia I. Rich, Malak M. Tfaily

Michigan Tech Publications

Introduction: Peatlands store up to a third of global soil carbon, and in high latitudes their litter inputs are increasing and changing in composition under climate change. Although litter significantly influences peatland carbon and nutrient dynamics by changing the overall lability of peatland organic matter, the physicochemical mechanisms of this impact—and thus its full scope—remain poorly understood. Methods: We applied multimodal metabolomics (UPLC-HRMS, ¹H NMR) paired with ¹³C Stable Isotope-Assisted Metabolomics (SIAM) to track litter carbon and its potential priming effects on both existing soil organic matter and carbon gas emissions. Through this approach, we achieved molecule-specific tracking …