Digital Commons Network^™

The Effects Of Visual And Audio Secondary Cognitive Tasks During Landing: A Statistical Parametric Mapping Analysis Of Hip And Knee Biomechanics, Hillary Nguyen, Amber Lyle, Kevin Tran, Dominic Espinoza, Gerwyn Hughes

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 1367-1380, 2025. https://doi.org/10.70252/KGHI3479 ACL injuries often occur when athletes perform cognitive tasks while performing a landing/cutting movement. This study investigated the effects of secondary cognitive tasks on hip and knee biomechanics during single limb landing. Sixteen recreational athletes (10 females and 6 males, age: 21.6 ± 2.5 years, mass: 65.2 ± 8.9 kg, height 1.66 ± 0.07 m) performed landings on their dominant limb as a single task and while simultaneously performing secondary cognitive tasks (mental arithmetic) provided through audio and visual means. Hip and knee joint angles and moments were calculated in all …

Single Vs. Whole Muscle Group Assessments: Does The Specific Muscle Influence Its Association With Performance?, Carina M. Velasquez, Kealey J. Wohlgemuth, Mckenzie M. Hare, Kathryn E. Southall, Jacob A. Mota

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 11, 2025. Biometric Muscle size and echo intensity are thought to influence muscle function. Unfortunately, previous works often will examine a single muscle from a group of agonists as a metric of whole muscle performance. This approach may not always be the most appropriate to assess performance outcomes. The purpose of the study was to 1) quantify the association of muscle size and echo intensity with vertical jump performance (VJ), 2) Compare the associations between individual and whole muscle group size and echo intensity, 3) determine whether single or …

Life As An Intern For Njit Stem For Success, Christopher Tava

STEM Month

I joined the STEM for Success Team in May 2023 with two main goals. The first goal was to reach 100 hours worth of contributions, as part of a mandatory internship requirement to graduate from the Academy for Mathematics, Science, & Engineering (AMSE). I reached that goal by early October 2023, although I have been motivated to continue my work with NJIT beyond that hour target. The second goal was to accomplish something that I was proud of with the resources that the New Jersey Institute of Technology (NJIT) provided me. I had heard of former students of AMSE that …

Epigenetic Landscape In Lysosomal Storage Disorders: Mechanisms And Modulation, Andrés Felipe Leal, Harry Pachajoa, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Lysosomal storage disorders (LSDs) are rare substrate-accumulating diseases primarily characterized by mutations in genes encoding proteins involved in lysosomal function, most of which have enzymatic activity. Resulting lysosomal dysfunction leads to the overaccumulation of non- or partially degraded substrates. While it is true that enzyme deficiency is the primary cause of LSDs, the epigenetic alterations in DNA methylation, miRNA expression, and histone modifications appear to be critical mechanisms involved in the pathogenesis of LSDs. As epigenetic marks are, in most cases, reversible, their study becomes vital to developing strategies aimed at reversing epigenome alterations. Although classical therapeutic alternatives aim to …

Reprogramming Tumor Microenvironment Via Systemic Delivery Of Tlr3 Agonist And Manganese Nanoparticle, Young Seok Cho, Xingwu Zhou, Xiaoqi Sun, Ziye Wan, Julia Crowther, Mariko Takahashi, Swetha Kodamasimham, Qi Wu, May Thazin Phoo, Youngseo Na, Kai Han, Zaiye Li, Anna Schwendeman, Steven P Schwendeman, Yu Leo Lei, James J Moon

Faculty, Staff and Student Publications

Toll-like receptor (TLR) agonists, as potent immunostimulatory adjuvants, play a critical role in linking the innate and adaptive immune responses. However, their antitumor effects as cancer immunotherapeutic agents have been limited. Here, we report our finding that manganese ion (Mn2+) potentiates various TLR agonists, leading to robust activation of the TLR pathway and the stimulator of interferon genes (STING) pathway among innate immune cells. In particular, we have observed robust antitumor efficacy after intratumoral administration of a TLR3 agonist and Mn2+. To achieve systemic codelivery of TLR3 agonist and Mn2+, we have developed a low-molecular-weight poly(inosinic:cytidylic acid)-Mn2+ coordination lipid nanoparticle …

Comparing Lower Extremity Kinematics Using Trazer And Inertial Motion Capture Systems, Gabriella Juoza-Clark Spt, Joellen Carter Spt, Nikki Stam Spt, Kevin Robinson Pt, Dsc, Ocs

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Introduction: This study assessed the validity of a non-immersive body motion tracking system (TRAZER) as an alternative to using Inertial Measurement Units (IMU)-based motion capture (MyoMotion) for lower extremity kinematic analysis. Methods: Twenty healthy participants (10 females, 10 males) with a mean age of 24.03 years (range: 20-33 years) and a mean BMI of 25.15 kg/m² (range: 18.45-32.23 kg/m²) performed double and single-leg squats. Data Analysis: Kinematic data from TRAZER and MyoMotion IMUs were compared using a mixed two-way ANOVA. Results: No significant differences were observed in knee flexion data across all movements (p > 0.05) and knee abduction during the …

Assessing The Role Of Social Media As A Complementary Source In Pharmacovigilance: Insights From Faers, X (Formerly Twitter), And Askapatient Data Across Multiple Drug Classes, Nwanneka Okere

Dissertations

Background: Adverse drug reactions (ADRs) pose significant public health challenges yet remain substantially underreported in traditional pharmacovigilance systems. Social media platforms and patient-reported outcome forums have emerged as potential complementary sources for capturing real-time patient experiences with medications, but their integration with established surveillance systems remains underexplored.

Purpose: This study examined ADR reporting patterns across FDA Adverse Event Reporting System (FAERS), X (formerly Twitter), and Askapatient to evaluate whether patient-generated digital data can complement traditional pharmacovigilance systems for enhanced drug safety monitoring.

Methods: An explanatory sequential mixed-methods design analyzed 107,753 reports representing 289,740 individual ADR occurrences for …

An Integrated Ca–Markov Modeling Framework For Forecasting Land Use And Land Cover Dynamics In Arkansas, Usa, Rasool Vahid, Mohamed H. Aly

Environmental Dynamics Faculty Publications and Presentations

Land use and land cover (LULC) changes significantly shape urban environments and directly impact ecological and socioeconomic systems. This study aims to explore these interconnections by employing the Cellular Automata–Markov (CA–Markov) model to assess and predict LULC dynamics in Arkansas. Historical LULC datasets from 2001 to 2021, obtained from the National Land Cover Database, were simplified from 11 into 5 classes to facilitate analysis and effectively map transitions. The model was validated by predicting LULC for 2016 and 2021 and comparing the predictions with the real maps, achieving an overall accuracy of approximately 91.9%, using model validation metrics, including precision, …

Correcting Class Imbalance Through Synthetic Training Data And 3d Modeling For Carabid Pitfall Trap Sampling, Blair Mirka

Geography ETDs

Crowdsourced biodiversity data provide an accessible foundation for large-scale ecological monitoring, but class imbalance limits automated species identification, particularly for rare taxa. This research explores the use of synthetic training data generated from 3D models of carabid beetle museum specimens to improve detection and classification performance for underrepresented species in crowdsourced datasets. High-resolution 3D models were created to simulate variation in lighting, orientation, and background. These synthetic images were incorporated into convolutional neural network training datasets at varying synthetic-to-real ratios to assess their impact on classification accuracy. Models were evaluated using controlled pitfall-trap imagery to examine the influence of scene …

The Effect Of High-Intensity Interval Training On Visceral Adipose Tissue In Type 2 Diabetes: A Systematic Review, Ivan D. Delgado, Julio C. Delgado, Ryan D. Burns

International Journal of Exercise Science

International Journal of Exercise Science 18(5): 1321-1333, 2025. https://doi.org/10.70252/YEUF2363 Visceral adipose tissue (VAT) is a significant contributor to insulin resistance in type 2 diabetes (T2D). The effectiveness of time-efficient high-intensity interval training (HIIT) in reducing VAT has not been reviewed. A systematic search conducted on PubMed, Embase, and SPORTDiscus up to April 2025 for randomized controlled trials that compared HIIT with non-exercise control and quantified VAT using imaging identified five trials (n = 138) that met inclusion criteria. Risk of bias was assessed using a nine-item modified PEDro scale. Four trials reported significant reductions in VAT after 8-12 weeks of …

Native Bee Assemblages In Prescribed Fire-Managed Prairies: A Case Study From Arkansas, United States, Coleman Z. Little, Neelendra K. Joshi

Entomology and Plant Pathology Faculty Publications and Presentations

Native bee communities in Arkansas remain poorly documented, particularly within fire-managed prairie ecosystems that provide critical habitat for pollinators. This study surveyed bee assemblages at two native prairie remnants in the Arkansas River Valley, one large (Cherokee Prairie Natural Area, CPNA) and one small urban fragment (Jewel Moore Nature Reserve, JMNR), both managed using prescribed fire. Using pan trapping, we recorded 599 individuals representing 96 species across 25 genera, including 49% singletons. Despite differences in size and landscape context, both prairies supported similarly rich bee communities per sample day, with JMNR and CPNA averaging 16.1 and 13.75 species, respectively. However, …

Untargeted Metabolomics Reveals Organ-Specific And Extraction-Dependent Metabolite Profiles In Endemic Tajik Species Ferula Violacea Korovin, Sylhiya Mavlonazarova, Kenneth Acosta, Rinat Abzalimov, Saidbeg Satorov, Vyacheslav Dushenkov

Publications and Research

Ferula violacea Korovin, an endemic Tajikistani plant with purported medicinal properties, remains understudied. This study employs untargeted metabolomics to characterize the metabolite profiles of ethanol extracts and juices from F. violacea roots and seeds. In total, 540 distinct metabolites are putatively identified, 419 of which are previously unreported in the Ferula genus, representing a substantial expansion of its known chemical diversity. The most abundant metabolites are terpenoids, amino acid derivatives, and alkaloids. A particularly abundant group of daucane sesquiterpenoids, sharing a common (6-methyl-azulen-4-yl) cyclohexanecarboxylate substructure, is identified, including known metabolites such as ferutidin and ferutinin. Comparative analysis reveals organ-specific metabolic …

Michigan Academician Volume 50, Issue 1

Michigan Academician

2025 Michigan Academy Conference abstracts.

Development Of Problem-Based Learning Worksheet Toenhance Ecoliteracy: Human Impact On Ecosystem, Ulina M.S. Simangunsong, B. Manurung, Martina Asiati Napitupulu

Jurnal Pendidikan Sains

Ecoliteracy (ecological literacy) is an individual's ability to understand basic ecological principles and make environmentally responsible decisions. Improving ecoliteracy is a crucial foundation for realizing Education for Sustainable Development (ESD), which prepares students to become proactive citizens in protecting the environment. The problem-based learning model helps students learn on their own by using real-world environmental cases to get them to think critically and solve problems. Therefore, this research aims to determine the effectiveness of using problem-based learning worksheets to enhance the ecoliteracy of seventh-grade students. The development model used is 4-D. The research instruments include expert validation forms for subject, …

Development Of E-Lkpd Assisted By Phet Colorado Basedon Discovery Learning: Critical Thinking Skills On Lightmaterial At Junior High School, Flora Yani Saragih, Pintor Simamora

Jurnal Pendidikan Sains

Critical thinking is necessary for 21st-century pupils, but PISA data suggest that Indonesian students, especially junior high school students, lack it. The junior high science/physics light material is abstract and involves in-depth reasoning (reflection, refraction, and shadow generation). Without critical thinking, kids memorize formulas or notions without analyzing real phenomena. Discovery learning involves pupils discovering concepts via observation and experimentation. Critical thinking requires initiative, exploration, and reasoning, which these foster. Therefore, this study aims to develop E-LKPD based on Discovery Learning assisted by an interactive simulation of PhET Colorado to strengthen the critical thinking skills of grade VIII students on …

Guided Inquiry Learning Assisted By Crossword Puzzlemedia: Student Scientific Literacy And Critical Thinkingability For Middle School, Agis Putri Niswa, Mariati Purnama Simanjuntak, Ramlan Silaban, Fauziyah Harahap, Ridwan Abdullah Sani

Jurnal Pendidikan Sains

Scientific literacy and critical thinking skills are two fundamental competencies that students need in the 21st century. Scientific literacy is essential for students to understand and use scientific knowledge to make informed decisions, while critical thinking trains students to analyze information, evaluate arguments, and solve problems logically. Therefore, the intent of this study was to determine the effect of the guided inquiry learning model assisted by crossword puzzle media on students’ scientific literacy and critical thinking skills. The type of research used was quasi-experimental with a two-group pretest-posttest design. The sample consisted of two classes: class VII-8 as the control …

Parameterizing Ion–Lipid Interactions From Local Clusters To Reproduce Experimental Bulk Properties Of Lipid Bilayers, W. Matthew Saunders

USF Tampa Graduate Theses and Dissertations

Phospholipids are the main component of cell membranes, providing a delimiting boundary for cells from their environments or from their organelles from the cytosol. Thiscompartmentalization allows cells to maintain quite different solutions within their cells and organelles, including different mixtures dissolved ions. Consequently, these membranes are constantly flanked by complex mixtures of salts at varied concentrations. To study membrane structure, one cannot neglect the contribution of the salts in the local solution. Ions perturb bilayer structure via specific interaction with the phospholipids, primarily with the headgroups. Experimental studies of these systems are somewhat at odds — scattering experiments with different …

Compadre: Combined Pedigree-Aware Distant Relatedness Estimation For Improved Pedigree Reconstruction, Grahame F Evans, James T Baker, Lauren E Petty, Alexander S Petty, Hannah G Polikowsky, Ryan J Bohlender, Hung-Hsin Chen, Che-Yu Chou, Kathryn Z Viljoen, Janet M Beilby, Shelly Jo Kraft, Wanying Zhu, Joshua M Landman, Autumn R Morrow, Dayi Bian, Alyssa C Scartozzi, Chad D Huff, Jennifer E Below

Faculty, Staff and Student Publications

Designing powerful and unbiased genomic studies requires accurate assessment of familial relatedness even when this information is not captured from participants. Characterization of pairwise degrees of relatedness from participants' genetic data enables reconstruction of pedigrees, and several pedigree reconstruction tools have emerged in the last decade. However, limitations of these tools include high computational burden in large datasets, reliance on external information, reduced accuracy in admixed populations, and most notably, an inability to accurately reconstruct pedigrees when only a subset of family members is represented in the genetic data. To improve pedigree reconstruction in large-scale data and in pedigrees with …

Menin Inhibitor Ds-1594b Drives Differentiation And Induces Synergistic Lethality In Combination With Venetoclax In Acute Myeloid Leukemia Cells With Rearranged Mixed-Lineage Leukemia And Mutated Nucleophosmin-1, Valerio Ciaurro, Vassilena Sharlandjieva, Anna Skwarska, Catherine Chahrour, Natalia Baran, Zhihong Zeng, Cassandra Ramage, Naval Daver, Bing Z Carter, Sovira Chaundhry, Palaniraja Thandapani, Maria Paola Martelli, Thomas A Milne, Marina Konopleva

Faculty, Staff and Student Publications

Mixed-lineage leukemia (MLL) rearrangements and Nucleophosmin-1 (NPM1) mutations are associated with acute leukemias whose pathogenesis is critically influenced by protein-protein interactions between menin and MLL. We hypothesized that targeting the menin-MLL interaction using DS-1594b and blocking the antiapoptotic BCL-2 protein using venetoclax may promote differentiation and enhance eradication of MLL-rearranged and NPM1-mutated leukemias models. We treated acute myeloid leukemia (AML) cell lines with MLL rearrangements, NPM1 mutations, other leukemias and primary samples from AML patients with venetoclax alone, DS- 1594b alone, and their combination. We measured proliferation, viability, apoptosis, and differentiation using a variety of cellular assays, Western blotting, and …

The Effects Of Caffeine And Resistance Exercise On Pulse Wave Reflection In Resistance-Trained Women, Sarah G. Kearney, Therese M. Smith, Meredith C. Paskert Joplin, Erica Marshall, Jason C. Parks, Stacie M. Humm, Michelle A. Kern, J. Derek Kingsley

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 1310-1320, 2025. https://doi.org/10.70252/RWDY4284 Caffeine, alone or in conjunction with an acute bout of resistance exercise (RE), increases measures of pulse wave reflection (PWR), with most studies focusing on men. Therefore, the purpose of this study was to investigate caffeine’s effects on measures of PWR alone and following an acute bout of RE in young, healthy, resistance-trained women. Eleven resistance-trained women completed an acute bout of RE using free-weights with repetitions to failure for squat and bench press with caffeine (4mg/kg) and a placebo. Measures of PWR were measured at Rest, 50 minutes following ingestion …

The Head-Direction Signal Is Generated From Two Types Of Head Direction Cells In Brainstem Nuclei, Ryan M. Yoder

Psychology

Head direction (HD) cells discharge based on an animal's directional heading. Computational models propose that a ring-attractor network across the connections between the lateral mammillary (LMN) and dorsal tegmental nuclei (DTN) underlies the signal's generation. These models contain neurons that encode either HD or angular head velocity (AHV), but also require cells that are sensitive to both parameters conjunctively (HD + AHV). Here we identify both types of HD cells in the LMN and DTN of female rats, with one population sensitive to AHV (both symmetric and asymmetric), and the other population insensitive to AHV. Notably, many HD + AHV …

Strengthening The Utah Diabetes Cook Along Program For Statewide Extension Delivery: Curriculum Refinement And Randomized Controlled Trial, Carrie Durward

Funded Research Records

No abstract provided.

Evaluating Soil Responses To Three Different Tillage Practices, Robert L. Burchett, Cordale L. Straub Senior, Logan D. Renfrow Sophomore

Scholars Week

Evaluating Soil Responses to Three Different Tillage Practices

Luke Burchett, Logan Renfrow, and Cordale Straub

Mentor: Dr. Iin Handayani Ph.D

Hutson School of Agriculture, Murray State University, Kentucky, USA

ABSTRACT

Tillage systems can greatly affect soil health by changing its structure, chemistry, and biological activity. This study examined how soil organic carbon (SOC), soil pH, soil moisture, soil organic matter (SOM) responds under three tillage systems: no-till, biannual tillage, and conventional tillage. Soil samples were taken from a 1–7.6 cm depth during September 2025 across three locations. The no-till site was located in Caldwell County, Kentucky, on an irrigated double-crop …

A Fine Lady And Excellent Field Botanist: Sister Remberta Westkaemper, O.S.B., Stephen G. Saupe

Biology Faculty Publications

This report provides a brief biography of Sister Remberta and an overview of her botanical activities

New Butterfly Taxa And Findings From Genomic Analyses, Jing Zhang, Qian Cong, Jinhui Shen, Leina Song, Nick V. Grishin

The Taxonomic Report of the International Lepidoptera Survey

Continuing our genomics-driven exploration of butterfly taxonomy, we integrate phylogenetic trees from all protein-coding genes with existing taxonomic and phenotypic knowledge and uncover further insights into butterfly systematics. As a result, one subgenus, 44 species, and 11 subspecies are proposed as new (type species in original combinations or type localities are listed in parentheses): Porphaurea Grishin, subgen. n. (Phoenicops porphyropis Meyrick & Lower, 1902) of Chaetocneme C. Felder, 1860 in Hesperiidae Latreille, 1809; Dione (Agraulis) lamasi Grishin, sp. n. (Peru: Cuzco) in Nymphalidae Rafinesque, 1815; Lasaia (Lasaia) chiapis Grishin, sp. n. (Mexico: Chiapas), Lasaia …

Improving Coral Restoration Outcomes Through Novel Molecular Applications, Matthew H. Gamache

USF Tampa Graduate Theses and Dissertations

Coral reef ecosystems are declining globally from numerous stressors, including localized pollution, disease, and marine heatwaves induced by climate change. To preserve these ecosystems, it is critical to identify corals that can withstand stressors—primarily future marine heatwaves—and prioritize them for coral restoration efforts until these stressors are mitigated. Coral responses to thermal stress can be influenced by several partners, including mutualistic microalgae and a vast prokaryotic community. Here, I use advanced molecular techniques to examine which partners (coral host, algal symbiont, and microbial communities) are associated with coral health, how they contribute to holobiont physiology, and their potential to increase …

Effects Of Combining Traditional East Asian And Conventional Western Medicine On Acute Stroke Outcomes, Dong-Seok Gwak, Jong-Sik Lee, Dawid Schellingerhout, Jinyong Chung, Hyerin Oh, Sang-Wuk Jeong, Ji Sung Lee, Hee-Joon Bae, Mikyung Kim, Dong-Jun Choi, Dong-Eog Kim

Faculty, Staff and Student Publications

Background: Traditional East Asian medicine (TM) is widely used in Korea and other East Asian countries. However, the effects of TM treatment on acute ischemic stroke (AIS) outcomes remain unclear, as previous studies lacked a sufficient sample size, a consecutive series design, or a prospective outcome capture approach. We aimed to investigate whether combining TM with conventional Western medicine (CM) treatments (C+TM) leads to better outcomes after AIS, relative to CM treatment alone.

Methods: We retrospectively analyzed 2157 consecutive patients with AIS from a prospectively collected registry (2011-2021) at our center and compared the CM and C+TM groups in terms …

What’S On Our Shores? A Study Of Marine Debris And Cigarette Litter Concentrations In Daytona Beach, Fl., Noelle-Marie T. Steele, Lisa Glover, Parisa Embrahimbabaie Dr, Kelly Sanantonio, Hyun Jung Cho Dr

Sustainability Conference

Marine debris, defined by the National Oceanic & Atmospheric Administration (NOAA), is any persistent, artificial, or processed solid material discarded into the marine and coastal environment. This growing global issue poses significant threats to marine life, coastal ecosystems, and human health. The present study aimed to assess the amount and types of marine debris, with an emphasis on cigarette butts, at two public beaches in Daytona Beach, Florida, a highly urbanized and heavily visited tourist location. Field surveys were conducted from April through July 2025 at the oceanfront beaches of Sunsplash Park and Main Street Pier using transect-based NOAA Marine …

Comparative Analysis Of Probiotic Viability In Alcoholic And Non-Alcoholic Kombucha, Isabella N. Cerrone, Brooke Pirkle, Danielle Williamson, Gianna Vendrell, Chloe Kraft

Humboldt Journal of Microbiology

Kombucha is a fermented tea beverage valued for its probiotic and antimicrobial properties that arise from complex molecular interactions between yeast, acetic acid bacteria (AAB), lactic acid bacteria (LAB), and metabolic byproducts of fermentation. With the rising demand for non-alcoholic versions of traditionally alcoholic kombucha beverages, ethanol reduction methods have become common, though their impact on probiotic viability and antimicrobial properties remains poorly understood. This study investigates the effects of ethanol removal on kombucha’s functional properties, including probiotic survival, antimicrobial activity, and organic acid composition (pH). We compared alcoholic and non-alcoholic versions of JuneShine kombucha across five flavors. Probiotic viability …

Growth Trends In Abundance And Diversity Of Synthetic Microbial Communities Over Varying Thermal Conditions, Mariska M. Kessler, Jocelyn Wolfinger, Destiny S. Alcaraz

Humboldt Journal of Microbiology

Microorganisms create various communities that act as the foundation of ecosystems. Abiotic factors such as temperature variability and environmental fluctuations are known to produce shifts in the abundance and diversity of microbial communities, but our current understanding is limited. In this study, we aimed to address this gap by observing abundance and diversity growth patterns under different temperature conditions within individual species and communities. Samples of 4 isolates and 4 artificial communities were grown at constant and fluctuating temperatures. Results found that the isolate samples had the highest abundance under constant high temperatures, whereas the community samples had the highest …