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The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough

Senior Honors Theses

Music influences emotion, physiology, and cognition, yet little is known about how the frequency it is tuned to affects these influences. Prior research has shown that music tuned to 432 Hz can reduce stress, lower blood pressure, and improve sleep. My colleagues and I conducted two studies to investigate this. Our research found that music tuned to 432 Hz promotes a significant increase in memory retention and induces a state of focus and relaxation. These results suggest that shifting from the standard tuning frequency of 440 Hz to 432 Hz could have a profoundly positive impact on our daily lives. …

Targeting Ribosome Biogenesis In Cic-Dux4 Sarcoma Treatment By Using Rna Polymerase 1 Inhibitors, Hema Sri Kambala

Theses

CIC-DUX4 sarcoma (CDS) is a rare, aggressive round-cell tumor that primarily affects children and young adults and is associated with poor clinical outcomes. Current treatments borrow from Ewing sarcoma regimens but offer limited benefit, underscoring the need for targeted therapeutic strategies. Transcriptomic analysis of CDS cell lines revealed a striking overrepresentation of ribosome biogenesis genes, indicating that CDS relies heavily on hyperactive RNA Polymerase I (Pol I)–driven rRNA synthesis. To evaluate this vulnerability, the Pol I inhibitors CX-5461 and BMH-21 were tested across multiple functional assays, including rRNA transcription, proliferation, migration, and 3-dimensional spheroid growth. Both inhibitors reduced rRNA synthesis …

Role Of Growth Factors In The Pathogenesis Of Systemic-Sclerosis-Associated Fibrosis, Fabian A. Mendoza, Sonsoles Piera-Velazquez, Sergio A. Jimenez

Jefferson Institute of Molecular Medicine Papers and Presentations

Systemic Sclerosis (SSc) is a systemic autoimmune disease of unknown etiology characterized by a severe fibroproliferative vasculopathy and frequently progressive cutaneous and internal organ fibrosis. The small-vessel vasculopathy and the tissue fibrotic alterations are responsible for the most serious clinical and pathological manifestations of the disease and for its high mortality. Despite the high severity and frequent mortality, there are currently no optimal therapeutic approaches for SSc, and its complex pathogenesis has not been fully elucidated. Numerous studies have suggested that growth factors and related regulatory macromolecules released from inflammatory and other cells present in the affected tissues play a …

Propelling Aging-Related Initiatives In A Next-Gen Cooperative Extension System: Editors’ Introduction To The Jhse Special Issue On Aging, Erin L. Martinez, James S. Bates

Journal of Human Sciences and Extension

No abstract provided.

Full Issue, Volume 13, Number 2, James S. Bates, Donna J. Peterson Dr., Scott Cummings, Erin L. Martinez

Journal of Human Sciences and Extension

No abstract provided.

Community Partnerships To Address Social Determinants Of Health Among Older Adults, Cory Bolkan, Raven Weaver, Cheryl Eschbach, Erik Geissal, Breanne Wise-Swanson

Journal of Human Sciences and Extension

Focusing on social determinants of health (SDOH) among older adults is key to addressing health disparities, maintaining independence in their homes/communities, improving health outcomes, and avoiding high-cost institutional care. While primary care settings are equipped to meet older adults’ physical health needs, the network of Area Agencies on Aging (AAA) is designed to meet social needs (e.g., transportation, nutrition, caregiver support). Yet, cross-sector community partnerships between AAAs and primary care are rare. This article shares an evaluation of one such partnership, where SDOH screenings were routinely implemented in primary care, yielding social prescribing and direct referral to AAA’s support services. …

Learning From The Roost: An Exploration Of Public Perceptions And Education Around Grey-Headed Flying Foxes At Centennial Parklands, Sydney., Gigi Pandole

Australia: Rainforest, Reef, and Cultural Ecology

Grey-headed flying foxes (Pteropus poliocephalus) have become a familiar feature of many Australian cities, and this visibility often prompts a mix of curiosity, uncertainty and concern. In Sydney, the long-term colony at Lachlan Swamp in Centennial Parklands brings thousands of visitors into close contact with the species each week. Some people respond with interest or appreciation, while others feel uneasy due to noise, smell or common misconceptions about disease. These everyday encounters raise an important question for conservation: how do people form their perceptions of flying foxes, and what role does education play in shaping coexistence in urban environments? This …

It's Alive! Comparing Wet And Dry Sclerophyll Revegetation In Wollemi National Park Following The 2019-2020 Bushfires, Bethany Hall

Australia: Rainforest, Reef, and Cultural Ecology

Wollemi National Park is part of the Greater Blue Mountains World Heritage Areas and contains many endemic plants and animals. Increasingly severe fires are threatening the area. This study aims to compare how dry and wet sclerophyll sites are recovering after the 2019-2020 Black Summer bushfires. We surveyed eight wet sites and nine dry sites that were burned early in the bushfires. Diameter at breast height (DBH) and resprouting vigor was measured to determine if and how well trees were recovering. Dry sites experienced higher resprouting vigor compared to wet sites. Wet sites had a higher number of unique trees …

Zero Textbook Cost Syllabus For Env 3070 (Agroecology), Benjamin Iuliano

Open Educational Resources

Our relationships with the food we eat are deeply personal, but also connect us to a wide array of people, plants, animals, and landscapes around the world. Encompassing a diversity of scholarly approaches, the field of agroecology seeks to understand the interactions among these components, draw attention to the consequences of our present industrial food system, and create the conditions for more sustainable and just futures. In this course, students will learn about the science, practice, and social movement of agroecology through lectures, course discussions, field trips, and hands-on activities.

J.A.M: What Epiphyte Load And Frugivore Abundance In Ficus Species Can Tell Us About Disturbance Regimes In Tropical North Queensland, Jordan Trinidad

Australia: Rainforest, Reef, and Cultural Ecology

The Wet Tropics Bioregion hosts a startling diversity of species, many of which are endemic and/or endangered. The habitats in which these species are found have been threatened by intensive logging post-European settlement, which has increased the susceptibility of the isolated remnant fragments to cyclone-related disturbances. In this study, we surveyed the visitation rates of frugivores to Ficus species between Cape Tribulation and Yungaburra in Northeast Queensland, Australia, as well as the epiphyte abundance supported by these trees. We found that in upland rainforest, the forces of cyclones and habitat fragmentation act in confluence on epiphyte abundance via the moderation …

Effects Of Provisioning On Two Species Of Rock-Wallaby (Petrogale Mareeba And Petrogale Assimilis) In North Queensland, Australia, Eve Oliker

Australia: Rainforest, Reef, and Cultural Ecology

Provisioning, the act of providing food, water, or shelter to wild animals, can lead to habituation, resulting in changes in behavior, abundance, and distribution (Newsome & Rodger, 2008). In North Queensland, a colony of Mareeba rock-wallaby (Petrogale mareeba) at Granite Gorge has been provisioned for over 45 years, mainly through direct hand-feeding, while a group of allied rock-wallaby (Petrogale assimilis) in Magnetic Island has experienced shorter and less consistent provisioning. This study investigated whether long-term provisioning causes more severe behavioral changes, higher aggression, and larger aggregation sizes. Approximately one week was spent observing each population. Scan sampling was utilized to …

Relating Natural Dispersal And Expansion Of Mangrove Forests To Local Australian Restoration Methods, August Jones

Australia: Rainforest, Reef, and Cultural Ecology

The combined vulnerability and importance of mangrove forests have spurred efforts to preserve their remaining natural stage and restore their land area made unsuitable by storms or coastal development. Globally, both private and government organizations have participated in mangrove ecosystem recovery through standard methodology and principles such as replantation and ecosystem rehabilitation. However, research into the costs and outcomes of these programs has ruled that many of them suffer low success rates due to a lack of suitable areas for rehabilitation, citing a poor understanding of the ecosystem typology and lack of long-term measures to avoid eventual degradation. This study …

Way Kambas National Park: The Human-Wildlife Conflict Success Story Still In Need Of Improvement, Eleanor Lefkowicz

Indonesia: Arts, Religion, and Social Change

This paper investigates the negative interactions between humans and animals in Way Kambas National Park of Sumatra, Indonesia, and the prevention and mitigation tactics the community utilizes. The numerous villages surrounding the National Park suffer from elephant activity damaging their farms, while the elephants are frequently harmed by poaching within the park. Participate observations and interviews concluded that the Way Kambas community responds to human-wildlife conflict with a collaborative effort by locals, government park police, and non-governmental organizations to both deter elephant presence outside of the park and poaching activity within the park, as well as to mitigate the negative …

The Imperative Of Regeneration: Exploring The Dimensions Of Tourism And Agriculture In Bali, Ava Whitney

Indonesia: Arts, Religion, and Social Change

This research centers on the impacts of mass tourism, development, and modernization on the landscape and culture of Bali and investigates regenerative alternatives in agriculture and tourism. Regenerative thinking offers a vision of travel and subsistence that preserves the ecology of the landscape and the integrity of Balinese culture. Organic farming and permaculture principles are traditional agricultural practices in Bali that have existed for generations, imbued with the Tri Hita Karana philosophy of Balinese Hinduism. Agriculture is a facet of Traditional Ecological Knowledge (TEK) that transmits ecological and cultural wisdom to future generations about how to relate to the natural …

Helping The Natural World Speak For Itself: Art's Role In Communicating Environmental And Sustainability Concepts In Sydney, Australia, Elizabeth Clark

Australia: Rainforest, Reef, and Cultural Ecology

Climate change and its broadening scope have made awareness of environmental issues, as well as ways to mitigate them, essential to securing our planet's future. Artistic venues, such as art galleries and even theatres, are becoming increasingly prominent in this conversation due to their ability to engage broad audiences and make scientific concepts more accessible. To understand the effectiveness of artistic efforts in science communication, it is necessary to assess the strategies by which both successful scientific venues, like zoos or natural history museums, and emerging artistic venues in science disseminate information. This project aimed to assess science communication strategies …

Native Seed Scoop, 2025 Fall Edition, University Of Northern Iowa. Tallgrass Prairie Center.

Native Seed Scoop

Contents:

--- Upcoming Events
--- What's Your Scoop?
--- TPC Highlights 2024-2025
--- Midwest Native Seed Network Requests Info
--- TPC Plant Materials Update
--- Flowering Splurge Stock Seed is "In the Bag"
--- A Scoop of Silence
--- Other Resources
--- In Memoriam - Carroll Hoksbergen

Use Of Modified Z-Domain Peptides To Specifically Label The Constant Region Of Immunoglobulin G And Vegf, Madeline Allen

Department of Chemistry: Dissertations, Theses, and Student Research

Antibodies are increasingly being used in medicinal therapies due to their ability to specifically bind to a target antigen. This fundamental behavior of antibodies has been used as a key component in drug development to address common problems with traditional drug molecules such as off-targeting, fast drug clearance, and low efficacy. This thesis provides some background into how antibodies can be used as potential treatments for a few diseases. Chapter 1 begins with an overview of the human immune system, and the role antibodies play within it. Then, the variety of ways in which antibodies can be used as medicinal …

Assessment Of Genes And Mirnas Expression In Alzheimer's Disease Samples Using Single And/Or Multiplex Preferential Amplification Pcr, Samanda F. Hickman

Theses (2016-Present)

Gene expression is measurable at the RNA and protein levels. It is a process by which genes produce functional products that are either non-coding RNAs or proteins. The non-coding RNAs or proteins of gene expression ultimately affect phenotype. Non-coding RNA (or mRNA) expression is measured by Northern blot or real-time quantitative PCR (RT-qPCR), while Western blot measures protein expression. Both require software to differentiate between the amounts of end products. Statistical analysis is employed to validate any differences among the measured values and to infer a correlation between the end products of various samples. There are several neurodegenerative diseases, including …

Assessing Expected Cover Of Invasive Flora Species Near Corridor Features By Distance, Joshua G. Logan

Theses

Fragmentation of landscapes has been a growing topic of interest within scientific literature over the past several decades, as the way we as humans affect our planet becomes more apparent as the years go on. As humans, we have shaped the land and what it contains in immeasurable ways, erasing or forever altering entire natural ecosystems. Chief among the drivers altering these ecosystems is the fragmentation of landscapes, which can have all kinds of effects on natural ecosystems, from limiting nutrient transport to providing easier access for invasives to permeate throughout a landscape. Corridors are significant areas of interest regarding …

(Si15-107) Mathematical Modeling Of Cancer Dynamics Stability Analysis Of Post Therapy Protection, Rajendran Swetha, Tharmalingam Gunasekar, Kamalendra Kumar, Krishnasamy Sakthivel

Applications and Applied Mathematics: An International Journal (AAM)

The study of PSITPS mathematical model is developed to analyze cancer dynamics, focusing on post-therapy protection. The model’s solution is rigorously examined for boundedness and positivity of solutions. Equilibrium points are identified, and numerical methods are employed to study stability. Simulations using accurate cancer data demonstrate the effectiveness of post-treatment protection in controlling cancer spread and minimizing recurrence. Stability analysis confirms the model’s predictive capability, offering valuable insights into long-term patient outcomes. The results highlight the importance of continuous post-treatment care in improving survival rates and reducing disease prevalence. This study provides a framework for optimizing cancer treatment strategies by …

Minority Farmer And Rancher Delinquency And Local Cultural Climate: Evidence From Farm Service Agency's County Office Committees, Lawson Connor, Bruce L. Ahrendsen, Charles B. Dodson, Logan Moss

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Farm delinquency is linked to many negative indicators of farm survival, including increased risk of bankruptcy and farm failure. Minority farmers and ranchers (MFR) have been found to exhibit higher rates of delinquency on U.S. Department of Agriculture (USDA) Farm Service Agency (FSA) loans compared to their non-Hispanic White male counterparts. These findings persist even after accounting for economic/financial factors expected to predict loan repayment performance. In this study, to further explore the existing discrepancy between loan default rates for MFR and White, non-Hispanic borrowers, we look more broadly than financial indicators and introduce MFR representation on the FSA County …

Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons

Theses and Dissertations

Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …

The Brain-Derived Neurotrophic Factor (Bdnf) And Its Importance To Organism Survival And Development, Christopher Monnett Smith

Holster Scholar Projects

Brain-Derived Neurotrophic Factor (BDNF) has been the subject of numerous studies regarding the functioning of the brain in relation to topics such as neural plasticity and neural survival. However, BDNF has also been implicated in the induction of changes not only in neural tissue but multiple other tissue types across the human body. The aim of this literature review is to provide a comprehensive, yet brief, overview of BDNF’s influence on the functioning of the nervous, cardiovascular, respiratory, muscular, and immune systems.

Valid And Accepted Novel Bacterial Taxa Isolated From Domestic Companion And Agricultural Animals Described In 2024, Sara D. Lawhon, Claire R. Burbick, Trinity Krueger, Elena Ruiz-Reyes, Ayden Wisney-Leonard, Mallory Lenmark, Erik Munson

Clinical Lab Sciences Faculty Research and Publications

Recognizing and updating bacterial names is key to communication between the veterinary clinical microbiology laboratory, veterinarians, and clients. Moraxella oculi sp. nov., distinct from Moraxella bovis and Moraxella bovoculi, was isolated from a cow with infectious bovine keratoconjunctivitis. Several respiratory pathogens were recognized, including Neisseria leonii sp. nov. described from rabbits, Mannheimia indoligenes sp. nov. described from cattle in Europe, and Moraxella haemolytica sp. nov. described from a goat in China. Stenotrophomonas forensis sp. nov. is a novel designation within the Stenotrophomonas maltophilia complex associated with isolates derived from horses. New additions to the Campylobacter genus included Campylobacter californiensis …

Chemistry And Biochemistry Affiliated Publications: Snapshot Of The Research Publications 2019-2024., Jeremy J. Smith, Lutishoor Salisbury

University Libraries Faculty Publications and Presentations

This report highlights the chemistry and biochemistry faculty publications for the period 2019-2024. It includes tables identifying the types of publications, the characteristics of the authors, inter-departmental and external cooperation, summary of the citations of the publications, and the JCR ranking of the journals in which they published.

Growing South Dakota (Fall 2025), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Mesonet at SDState: A benefit to every South Dakotan
[Page] 6 Governor’s Ag Ambassador — Glenn Muller
[Page] 8 Precision agriculture cooperative agreement signed with University of Debrecen
[Page] 10 Students experience international agriculture, culture in Vietnam, New Zealand
[Page] 12 Legen-dairy! SDSU students claim national judging awards
[Page] 13 SDSU Rodeo Team continues storied rodeo tradition at nationals
[Page] 14 SDSU wheat breeders helping feed the world
[Page] 20 SDSU drone holds promise for soil, leaf sampling
[Page] 22 Don't be a fish out of water
[Page] 24 A passion for academic advising
[Page] 25 One takeaway …

Hungry Minds: Analyzing The Impact Of Food Insecurity And Food Assistance Programs On Neurocognitive Development And Childhood Mental Health, Kayla A. Davenport

Senior Theses

Introduction: Food insecurity affects millions of children in the United States and is increasingly recognized as a significant risk factor for poor nutritional intake and adverse health outcomes. However, less is known about how the experience of food insecurity disrupts healthy development and well-being, particularly among American youth. This thesis had two aims: (1) to examine the relationship between household food insecurity and children’s neurocognitive and mental health outcomes and (2) to evaluate how major food assistance programs address, or fail to address, these developmental risks.

Methods: This thesis uses a mixed-methods approach, integrating a narrative literature review, a cross-sectional …

Factors Associated With Medication Adherence Among Patients With Attention-Deficit/Hyperactivity Disorder (Adhd), Linh Nguyen, Yen-Chi L Le, Hannah Reygaerts, Todd R Johnson, Cesar A Soutullo

Faculty, Staff and Student Publications

Objective: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common behavioral health condition that impacts 5% to 8% of children and 2.5% of adults worldwide. The symptoms of ADHD are effectively managed with medication, yet patients with ADHD may inconsistently take their medication. We assessed medication adherence among patients with ADHD and identified factors associated with medication adherence that may be utilized to optimize adherence.

Method: This is a retrospective, observational study among patients aged 4 years and older with a diagnosis of ADHD at primary care and multispecialty outpatient clinics during May 2021 to May 2023. We assessed sociodemographic characteristics, stratified by …

Grpa-Prs: A Risk Stratification Method To Identify Genetically-Regulated Pathways In Polygenic Diseases, Xiaoyang Li, Brisa S Fernandes, Andi Liu, Jingchun Chen, Xiangning Chen, Zhongming Zhao, Yulin Dai

Faculty, Staff and Student Publications

Introduction: Polygenic risk score (PRS) assesses genetic risk for diseases, yet some high-risk individuals avoid illness while low-risk individuals develop it. We hypothesize that unknown counterfactors may reverse PRS predictions, offering insights into disease mechanisms and interventions.

Methods: We developed a novel framework to identify genetically-regulated pathways (GRPas) using PRS-based stratification in Alzheimer's disease (AD) and schizophrenia (SCZ) cohorts. We calculated PRS models, stratified individuals by risk and diagnosis, and analyzed differential GRPas. For AD, analyses were further conducted with and without apolipoprotein E (APOE) effects, and across APOE haplotype.

Results: In AD, we identified several well-known AD-related pathways, including …

Design And Development Of An Intervention To Improve The Quality And Safety Of Pediatric Dental Sedation: A Human-Centered Design Approach, Kawtar Zouaidi, Jan Yeager, Suhasini Bangar, Sayali Tungare, Urvi Mehta, Janelle Urata, Alfa-Ibrahim Yansane, Thomas Tanbonliong, Jungsoo Kim, Emily Sedlock, Krishna Kumar Kookal, Yan Xiao, Tokede Oluwabunmi, Heiko Spallek, Amy Franklin, Gregory W Olson, Joel White, Elsbeth Kalenderian, Muhammad F Walji

Faculty, Staff and Student Publications

Background: There are gaps in understanding the experiences of children, parents, and providers during dental conscious sedation. This study aimed to capture and analyze these experiences to identify opportunities for improvement and enhance the quality and safety of pediatric dental conscious sedation.

Methods: A human-centered design approach was used to examine the conscious sedation experience in 2 US advanced education pediatric dental clinics. Researchers conducted field observations, interviews with providers and parents, and providers focus groups to explore experiential factors. Data were transcribed and analyzed using content thematic analysis. Insights from the data were used to explore and generate new …