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Association Of Hair Shedding Level With Cow–Calf Performance In Summer-Bred Dexter Cattle, Ichard Browning Jr, Emily G. Hayes, Kaylee S. Hillin, Maria Lenira Leite-Browning Jan 2026

Association Of Hair Shedding Level With Cow–Calf Performance In Summer-Bred Dexter Cattle, Ichard Browning Jr, Emily G. Hayes, Kaylee S. Hillin, Maria Lenira Leite-Browning

Food and Animal Sciences Faculty Research

Reduced winter hair shedding in beef cows through the spring and summer months may contribute to heat stress and reduced performance in spring-calving herds. This study evaluated the relationship of hair shedding with the fertility and maternal performance of 72 Dexter cows. Hair shedding data for 20 May, 3 June, 17 June, and 1 July in 2019 were used to classify cows as high or low hair shedders. Hair shedding levels were lower (p < 0.05) for 2-year-old cows than for cows 7+ years of age for the first three dates and lower (p ≤ 0.05) for lactating cows than for dry cows on the first two dates. Concurrent and four years of historical performance records were used to assess the associations between hair shedding and cow–calf performance. Data from 230 natural matings in July and August from 2015 to 2019 were analyzed. Birth to weaning weight data were recorded from 2016 to 2019 on 124 spring-born calves. Cow fertility was higher (p < 0.05) for high-shed cows than for low-shed cows for the 1 July classification. When the records from cows that were dry in 2019 were excluded from testing, fertility was higher (p < 0.05) for high-shed cows than for low-shed cows at all four scoring dates. The associations of cow hair shedding levels with preweaning calf performance were minimal. Dexter cows exhibiting higher hair shedding levels in the spring and summer expressed higher summer fertility.


Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang Jan 2026

Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang

Faculty Publications

Objectives: We aimed to investigate the effects of 6 weeks of leucine supplementation on athletic performance, central fatigue, and serum metabolome in endurance athletes, and to provide valuable insights into nutritional strategies for endurance athletes. Methods: Twenty cross-country skiers were recruited and randomized into 2 groups: the placebo (PLA) group and the leucine (LEU) group. Subjects were given leucine (8.5 g) + sucrose (14 g) or only sucrose (14 g) supplements twice each day from Monday to Saturday for 6 weeks. Test parameters include body composition, aerobic capacity, isokinetic muscle strength, blood biochemistry, and targeted metabolomics. Results: After intervention, compared …


Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum Jan 2026

Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum

ETDs from 2020-2029

The term Early Life Stress (ELS) encompasses traumatic events occurring before the age of 18 such as physical abuse, verbal abuse, household dysfunctions, sexual abuse, childhood neglect, child maltreatment, and adverse childhood experiences. The traumatic psychological and physical experiences in early life are widely known to cause enduring effects on mental and physical health in adulthood. Of note, individuals with ELS have adverse health outcomes earlier in adulthood and with more severity such as in the case of Systemic Lupus Erythematous (SLE), an autoimmune disease. The risk for autoimmunity and cardiovascular disease (CVD) increases with ELS exposure and CVD is …


Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten Jan 2026

Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten

ETDs from 2020-2029

Phenotypic switching of smooth muscle cells (SMCs) from a contractile to a synthetic state underlies the pathogenesis of several cardiovascular disease (CVD) pathologies, including restenosis and atherosclerosis. Leiomodin 1 (LMOD1), an SMC-enriched actin-binding protein, has been previously found to regulate SMC phenotypic modulation in vitro. However, its contribution to CVD development and progression, along with its influence on gene regulatory networks (GRNs) that inform underlying responses to stress, remains incompletely defined. Here, I combine a mouse injury model, bulk RNA sequencing, and GRN inference to define how reduced LMOD1 expression perturbs SMC physiology during vascular wall remodeling and lipid stress. …


Coexisting Salps Exhibit Distinct Feeding Selectivity On Microorganisms In The North Pacific Subtropical Gyre, Anne W. Thompson, Kylee Lamberson, Kelly R. Sutherland Jan 2026

Coexisting Salps Exhibit Distinct Feeding Selectivity On Microorganisms In The North Pacific Subtropical Gyre, Anne W. Thompson, Kylee Lamberson, Kelly R. Sutherland

Biology Faculty Publications and Presentations

Mortality mechanisms play an important role in how oceanic microorganisms contribute to global biogeochemical cycles. Salps are widespread pelagic tunicates known to remove phytoplankton from coastal and high-latitude waters, but their interaction with microorganisms in the vast tropical and subtropical gyres is not well quantified. Using quantitative measurements of six major marine microorganisms in the guts of six distinct but co-occurring salp species from the North Pacific Subtropical Gyre, we examined the impact and dynamics of salp feeding on marine microorganisms in a vast open ocean region. All salps preferentially removed prey greater than 1 μm in diameter, including marine …


Modulation Of The Cgas-Sting Inflammation Pathway In Mouse Models Of Accelerated And Slowed Aging, Benjamin David Heckman Jan 2026

Modulation Of The Cgas-Sting Inflammation Pathway In Mouse Models Of Accelerated And Slowed Aging, Benjamin David Heckman

ETDs from 2020-2029

Chronic sterile inflammation (inflammaging) is a core pillar of aging, and the cGAS-STING innate immune pathway has emerged as a key driver of this process. However, how this pathway intersects with systemic endocrine signaling remains poorly understood. Here, we investigated the intersection of endocrine signaling and cGAS-STING activation using two complementary mouse models with opposing lifespan phenotypes: a short-lived, liver-specific glucagon receptor knockout (LKO) mouse and a long-lived growth hormone-releasing hormone knockout (GHRH-KO) mouse. We demonstrate that despite presenting with a metabolically healthy phenotype, female LKO mice exhibited a significantly reduced lifespan. We link this premature mortality to a sex …


Reproductive System Variation In Tropical Red Macroalgae, Taylor M. Williams Jan 2026

Reproductive System Variation In Tropical Red Macroalgae, Taylor M. Williams

ETDs from 2020-2029

The reproductive system encompasses the relative rates of sexual versus clonal reproduction and is responsible for partitioning genetic diversity within and among populations. However, the quantification of these rates remains limited in natural populations and has primarily focused on animals and angiosperms. This knowledge gap is particularly acute among tropical macroalgae. This dissertation addresses this by focusing on the cryptogenic invader Chondria tumulosa in the Papahānaumokuākea Marine National Monument and the invasive species Acanthophora spicifera across the Hawaiian Archipelago, Australia, and Guam. For Chondria we developed nine microsatellite loci and found a dominance of tetrasporophytes, high clonal rates, and strong …


Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca Jan 2026

Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca

ETDs from 2020-2029

Triple-negative breast cancer (TNBC) and high-grade glioma (HGG) pose significant diagnostic and therapeutic challenges due to their aggressive biology and the limitations of [¹⁸F]FDG PET, which suffers from nonspecific uptake in inflammatory tissues, complicating differentiation of viable tumor from treatment-related effects. Computed Tomography, while strong for structural changes, has limited soft tissue contrast for distinguishing tumor from inflammation, and Magnetic Resonance Imaging, despite superior soft tissue resolution, struggles with differentiating active tumor from post-treatment changes like edema or necrosis due to nonspecific enhancement. These challenges highlight the necessity for complementary and advanced imaging strategies for improved diagnosis and monitoring. This …


Investigating Stromal Cell-Mediated Biomechanics For Angiogenesis And Reperfusion In A 3d Microfluidic Model For Ischemic Vascular Disease, Vaishali Bala Jan 2026

Investigating Stromal Cell-Mediated Biomechanics For Angiogenesis And Reperfusion In A 3d Microfluidic Model For Ischemic Vascular Disease, Vaishali Bala

ETDs from 2020-2029

Peripheral artery disease (PAD) affects millions worldwide, causing tissue ischemia and impaired healing due to insufficient blood flow. Current therapeutic strategies to promote revascularization remain limited, largely because the mechanical regulation of angiogenesis is poorly understood. While biochemical growth factors like VEGF have been extensively studied, the role of mechanical forces generated by stromal cells in the perivascular matrix remains underexplored. This dissertation investigated how stromal cell contractility drives vascular growth through mechanotransduction pathways and modulation of endothelial cell-cell junctions. Using 3D fibrin or fibrin-collagen-I-based microtissues and compartmentalized microfluidic devices, we characterized the mechanical phenotypes of multiple fibroblast populations and …


Stat-Independent Functions Of Janus Kinases 1 And 2 Are Obligatory For The Postnatal Development Of Mammary Epithelial Ducts, Rayane Dennaoui, Madison N. Wicker, Carson Moen, Michaela Schlederer, Kerry Vistisen, Aleata A. Triplett, Thomas Rülicke, Hallgeir Rui, Lukas Kenner, Emilio Casanova, Kay-Uwe Wagner Jan 2026

Stat-Independent Functions Of Janus Kinases 1 And 2 Are Obligatory For The Postnatal Development Of Mammary Epithelial Ducts, Rayane Dennaoui, Madison N. Wicker, Carson Moen, Michaela Schlederer, Kerry Vistisen, Aleata A. Triplett, Thomas Rülicke, Hallgeir Rui, Lukas Kenner, Emilio Casanova, Kay-Uwe Wagner

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Janus kinases 1 and 2 and STAT transcription factors are critical signaling nodes for numerous growth factors. In the mammary gland, JAK2 and STAT5a/b are essential for alveolar cell differentiation and lactation, but little is known about the cooperative roles of JAKs and STATs before pregnancy. We examined female mice conditionally deficient in JAK1/2 and discovered that both kinases jointly regulate epithelial cell proliferation and ductal morphogenesis. To assess the role of downstream STATs, we generated genetic models co-deficient in STAT3/5a/5b with or without STAT1 or JAK1. Although loss of STAT3/5a/5b leads to a JAK1-dependent upregulation of STAT1, the formation …


Integrated Proteomics To Understand The Role Of Neuritin-1 (Nrn1) As A Molecular Mediator Of Synaptic Resilience In Alzheimer’S Disease, Derian Pugh Jan 2026

Integrated Proteomics To Understand The Role Of Neuritin-1 (Nrn1) As A Molecular Mediator Of Synaptic Resilience In Alzheimer’S Disease, Derian Pugh

ETDs from 2020-2029

Alzheimer’s disease (AD) is the leading cause of dementia in adults over the age of 65, and currently affects approximately 6.9 million people in the United States. By 2060, the number of people age 65 and older with AD is projected to reach 13.8 million, barring the development of disease-altering therapies to prevent, slow or cure AD. Thus, there is a need for progress in the understanding of AD pathophysiology, as well as in the development of diagnostic and therapeutic interventions. Approximately one-third of individuals without dementia at the time of death are found to harbor high levels of amyloid-beta …


Cysteine Protease Activity In Allergen Recognition And Initiation Of Th2 Allergic Responses, Audrey Rae Meloun Jan 2026

Cysteine Protease Activity In Allergen Recognition And Initiation Of Th2 Allergic Responses, Audrey Rae Meloun

ETDs from 2020-2029

Allergens are non-infectious environmental proteins that can trigger T helper 2 (Th2) cell-mediated inflammation in atopic individuals. Allergens are structurally diverse and typically lack pathogen-associated molecules patterns (PAMPs), which are recognized by pathogen recognition receptors (PRRs). PRRs are the canonical sensors of the innate immune system that typically detect PAMPs in microbes, initiating signaling pathways that drive pathogen clearance. Because allergens generally do not activate PRRs in the same way as infectious agents, alternative detection mechanisms are likely responsible for their recognition and the subsequent initiation of Th2 cell-mediated inflammation. House Dust Mite (HDM), a major indoor allergen, and other …


Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel Jan 2026

Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel

ETDs from 2020-2029

Trophoblast cell surface antigen 2 (Trop2) is closely related to the development and progression of triple-negative breast cancers (TNBC) and is also being investigated as a pan-cancer biomarker. Trop-2 tumorigenesis is mediated by the calcium ion signaling pathways. By accurately predicting and targeting Trop-2 for immunotherapy, precision therapy is crucial. Trop-2 is overexpressed in tumor tissues compared to normal tissues, which makes it a promising molecular target for cancer-targeted therapy. This thesis reports the development and preclinical evaluation of two novel Trop-2-specific radiopharmaceutical tracers derived from the clinically approved antibody-drug conjugate Sacituzumab Govitecan (SG): a full antibody drug conjugate-based tracer …


Beyond Neurons: Impact Of Cannabidiol On Glial Cells In Ischemic Stroke, Victória Linden De Rezende, Khiany Mathias, Cinara Ludvig Gonçalves, Rafael Mariano De Bitencourt, Tatiana Barichello, Fabricia Petronilho Jan 2026

Beyond Neurons: Impact Of Cannabidiol On Glial Cells In Ischemic Stroke, Victória Linden De Rezende, Khiany Mathias, Cinara Ludvig Gonçalves, Rafael Mariano De Bitencourt, Tatiana Barichello, Fabricia Petronilho

Faculty, Staff and Student Publications

Ischemic stroke triggers a complex cascade of events involving inflammation, oxidative stress, and glial cell dysfunction, all of which contribute to neuronal damage and impaired recovery. Glial cells (e.g., astrocytes, microglia, and oligodendrocytes) play key roles in neuroinflammatory responses, making them attractive targets for therapeutic modulation. Cannabidiol, a non-psychoactive phytocannabinoid from Cannabis sativa, exhibits anti-inflammatory, antioxidant, and neuroprotective properties. Preclinical evidence indicates that cannabidiol attenuates glial reactivity, reduces pro-inflammatory signaling, mitigates oxidative stress, and preserves blood-brain and intestinal barrier integrity in stroke models. Moreover, cannabidiol modulates key molecular pathways (e.g., nuclear factor-κB, tumor necrosis factor, and calcium-related signaling), contributing to …


Structures Of Invertebrate Pezo-1 Isoforms With A Compact Architecture And A Dispensable Pore-Distal N-Terminal Blade, Briar Bell, Angela M Jaramillo-Granada, Daniel J Orlin, Wei-Hsiang Weng, Haosheng Wen, Marcos Sotomayor, Alexander T Chesler, Matthew L Baker, Julio F Cordero-Morales, Valeria Vásquez Jan 2026

Structures Of Invertebrate Pezo-1 Isoforms With A Compact Architecture And A Dispensable Pore-Distal N-Terminal Blade, Briar Bell, Angela M Jaramillo-Granada, Daniel J Orlin, Wei-Hsiang Weng, Haosheng Wen, Marcos Sotomayor, Alexander T Chesler, Matthew L Baker, Julio F Cordero-Morales, Valeria Vásquez

Faculty, Staff and Student Publications

PIEZO channels are mechanosensitive ion channels conserved from plants to humans, yet structures exist for only a few mammalian orthologs. We define the structural and functional diversity of Caenorhabditis elegans PEZO-1, a single gene with extensive alternative splicing, by determining cryo-electron microscopy structures of three representative isoforms: G (full length), K (lacking the pore-distal N-terminal blade), and L (missing most of the blade). PEZO-1G displays mechanically evoked currents yet adopts a compact, semi-flattened conformation that significantly differs from the mammalian domes. The blades exhibit a three-step slope architecture stabilized by inter-blade latching among transmembrane helical units, yielding a circular, steering-wheel-like …


Structures Of Trpv1 Bound By Hyperthermia-Inducing Analgesics, Yu-Hao Gao, Yi-Zhe Huang, Zhao-Xing Li, Xiao-Ying Chen, Chang-Yan Shao, Han-Wen Li, Bin Liu, Fán Yang, Mei-Rong Chen, Mei-Ling Lu, Michael X Zhu, Fan Yang, Yi-Bei Xiao, Ye Yu Jan 2026

Structures Of Trpv1 Bound By Hyperthermia-Inducing Analgesics, Yu-Hao Gao, Yi-Zhe Huang, Zhao-Xing Li, Xiao-Ying Chen, Chang-Yan Shao, Han-Wen Li, Bin Liu, Fán Yang, Mei-Rong Chen, Mei-Ling Lu, Michael X Zhu, Fan Yang, Yi-Bei Xiao, Ye Yu

Faculty, Staff and Student Publications

TRPV1, a member of the transient receptor potential vanilloid subfamily, mediates nociception and thermoregulation. TRPV1-targeting analgesics frequently induce hyperthermia, underscoring the need for structural insights to guide the development of safer compounds. Here, we determined the structures of rat TRPV1 bound to the clinical candidate analgesics AMG517, AMG9810, and SB366791. AMG517 and AMG9810 are deeply situated within the S3-S4 interface of the vanilloid pocket, where they interact with residues from the S3-S6 helices, as well as the S4-S5 linker. These interactions induce local deformations in the TRP-box and lower S6 helix, accompanied by a modest rotation of the S1-S4 bundle, …


A Bovine Cell Line Resistant To Japanese Encephalitis Virus Entry But Permissive To Post-Entry Replication, Sang-Im Yun, Young-Min Lee Jan 2026

A Bovine Cell Line Resistant To Japanese Encephalitis Virus Entry But Permissive To Post-Entry Replication, Sang-Im Yun, Young-Min Lee

Animal, Dairy, and Veterinary Science Faculty Publications

Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic orthoflavivirus that poses a significant global health threat. It causes severe neuroinflammatory disease in humans and reproductive failure in swine. Because of the broad host range and cell tropism of JEV, identifying animal cell lines resistant to infection has been a persistent challenge. In this study, we demonstrate that Madin–Darby bovine kidney (MDBK) cells are resistant to JEV infection yet remain fully permissive to viral replication when transfected with viral genomic RNA. Using immunoblotting, immunofluorescence, and flow cytometry, we show that MDBK cells, unlike the highly susceptible baby hamster kidney (BHK-21) cells …


Mechanical Performance Evaluation Of Natural Composites Recycled Hemp Rice Bag Reinforced With And Without Silicon Carbide Particles, Gaber A. Elawadi, A. S. Fayed Jan 2026

Mechanical Performance Evaluation Of Natural Composites Recycled Hemp Rice Bag Reinforced With And Without Silicon Carbide Particles, Gaber A. Elawadi, A. S. Fayed

Mansoura Engineering Journal

Significant progress has been made in the development of natural fiber-reinforced composite materials, owing to their potential to enhance mechanical properties while offering a greener and more sustainable alternative to traditional materials. These materials combine superior ecological benefits with enhanced mechanical performance. This study examines how recycled hemp fiber bags, including recycled hemp fibers obtained from rice hemp fiber bags, affect the mechanical characteristics of unreinforced and reinforced composites. Four composite systems were fabricated and tested: (1) HFR (randomly chipped recycled hemp fiber bags–epoxy composite), (2) HFB (continuous recycled hemp fiber bag–epoxy composite), (3) HFR SiC (randomly chipped recycled hemp …


Zonation-Dependent Distribution Of Microplastic Occurrence In Patella Caerulea From Mersin Coast, Türkiye, Ezgi̇ Deği̇rmenci̇, Nuray Çi̇ftçi̇, Sedat Gündoğdu, Deni̇z Ayas Jan 2026

Zonation-Dependent Distribution Of Microplastic Occurrence In Patella Caerulea From Mersin Coast, Türkiye, Ezgi̇ Deği̇rmenci̇, Nuray Çi̇ftçi̇, Sedat Gündoğdu, Deni̇z Ayas

Turkish Journal of Zoology

Increasing plastic pollution has become a critical environmental issue, leading to  challenges in management. Specifically, microplastics (MPs) are of particular concern  because they can persist in aquatic ecosystems and adversely affect marine  organisms. The objective of this study was to assess the occurrence of MPs  in the soft tissues of Patella caerulea (Linnaeus, 1758) collected from the Mersin  Viranşehir coastal area. As no specimens were found in the supralittoral zone, the  decision was taken to conduct sampling only in the mediolittoral and infralittoral  zones. The total sampling area was 24 m2 divided into three 4-m2 plots in each zone.  A …


Blinking Without Eyelids: First Video-Documented Evidence Of A Blink-Like Reflex In Ophisops Elegans (Reptilia: Lacertidae), Turan Meri̇ç Çelebi̇, Yusuf Çeli̇kaği, Tuana Kinay, Arda Cem Kuyucu, Muammer Kurnaz, Mehmet Kürşat Şahi̇n Jan 2026

Blinking Without Eyelids: First Video-Documented Evidence Of A Blink-Like Reflex In Ophisops Elegans (Reptilia: Lacertidae), Turan Meri̇ç Çelebi̇, Yusuf Çeli̇kaği, Tuana Kinay, Arda Cem Kuyucu, Muammer Kurnaz, Mehmet Kürşat Şahi̇n

Turkish Journal of Zoology

Eyelids play a crucial role in protecting the eyes of vertebrates; however, certain  reptile species, such as Ophisops elegans, completely lack movable eyelids. In this  study, we present the first video-documented evidence of a blink-like reflex in O.  elegans, captured through endoscopic field observations and corroborated by laboratory video analysis. The observed movement consisted of a brief convex  deformation of the ocular surface, lasting approximately 0.3 s and resembling a blink  despite the presence of a fixed transparent brille. This behavior was observed once in  the field and twice under controlled laboratory conditions. We propose that O.  elegans may employ …


Growth Patterns And The Shift From Predominantly Female To Balanced Sex Ratios In Carassius Gibelio (Bloch, 1782): A Comparative Study Of Lotic And Lentic Populations In  Serbia, Tamara Mitić, Jelena Čanak Atlagić, Ana Marić, Jelena Stanković Ristić, Nikola Marinković, Momir Paunović, Predrag Simonović Jan 2026

Growth Patterns And The Shift From Predominantly Female To Balanced Sex Ratios In Carassius Gibelio (Bloch, 1782): A Comparative Study Of Lotic And Lentic Populations In  Serbia, Tamara Mitić, Jelena Čanak Atlagić, Ana Marić, Jelena Stanković Ristić, Nikola Marinković, Momir Paunović, Predrag Simonović

Turkish Journal of Zoology

Since its introduction into Serbian watercourses, the invasive Carassius gibelio (Bloch, 1782) (Prussian carp) has spread rapidly. This paper provides an up-to-date overview of the sex ratio, age structure, and growth parameters in Serbian  populations of this fish and describes how growth varies in two contrasting  ecosystems: lotic and lentic. A total of 133 individuals were sampled. The individuals  from lentic habitats were longer on average, with no significant differences in average  weight or age between the two ecosystem types. There was a difference in  the sex ratio between the ecosystems, as indicated by a higher proportion of males in …


An Antioxidant Cocktail Of Tert-Butylhydroquinone And A Manganese Porphyrin Induces Toxic Levels Of Oxidative Stress In Cancer Cells, Sandra Tamarin, Hannah Jung, Joseph Lamorte, Laura Biesterveld, Gabriel Piñero, Grace Turchetta, Molly Myers, Rebecca Oberley-Deegan, Aimee Eggler Jan 2026

An Antioxidant Cocktail Of Tert-Butylhydroquinone And A Manganese Porphyrin Induces Toxic Levels Of Oxidative Stress In Cancer Cells, Sandra Tamarin, Hannah Jung, Joseph Lamorte, Laura Biesterveld, Gabriel Piñero, Grace Turchetta, Molly Myers, Rebecca Oberley-Deegan, Aimee Eggler

Student Papers, Posters & Projects

Despite significant advancement in cancer treatments, therapies with minimal toxicity to healthy cells are still limited. One targetable weakness of cancer cells is their sensitivity to oxidative stress. We find that the combination of two antioxidants—the common food additive tert-butylhydroquinone (tBHQ) and a manganese porphyrin in clinical trials, MnTnBuOE-2-PyP5+ (MnBuOE)—increases oxidative stress and causes apoptotic death in several cancer cell lines, but not in mouse primary fibroblasts. Investigating the mechanism of cell death, MnBuOE is observed to catalyze the oxidation of tBHQ, producing the electrophilic quinone tert-butylquinone (tBQ). A critical role for tBQ and its electrophilic character was revealed with …


Habitat Diversity Or Altitudinal Gradient? Which Factor Better Explains Ground Beetle (Coleoptera: Carabidae) Biodiversity? A Case Study From Davraz Mountain (Isparta, Türkiye), Ebru Ceren Fi̇dan, Ali̇ Gök Jan 2026

Habitat Diversity Or Altitudinal Gradient? Which Factor Better Explains Ground Beetle (Coleoptera: Carabidae) Biodiversity? A Case Study From Davraz Mountain (Isparta, Türkiye), Ebru Ceren Fi̇dan, Ali̇ Gök

Turkish Journal of Zoology

Ground beetle (Carabidae) species diversity and spatial distribution were surveyed  across five habitat types along an elevational gradient on Davraz Mountain, a  biogeographical transition area in southwestern Türkiye. The analyses showed that  habitat heterogeneity—particularly soil moisture and texture—exerts a stronger  influence on carabid diversity than elevation. Sørensen’s and Jaccard similarity  indices showed strong faunal overlap between some sampling areas, while  multivariate principal components and canonical correspondence analyses verified  distinct environmental gradients influencing community structure. Diversity indices  indicated varying levels of species richness and evenness across sampling areas.  The data highlight the importance of fine-scaled habitat features in driving ground  beetle …


Dna Metabarcoding Approach To The Determination Of The Diet Spectrum Of The Common  Sunbleak Leucaspius Delineatus (Heckel, 1843), Elena V. Dzyuba, Yurij S. Bukin, Bakhtiar E. Bogdanov, Yulia P. Sapozhnikova, Natalia N. Denikina Jan 2026

Dna Metabarcoding Approach To The Determination Of The Diet Spectrum Of The Common  Sunbleak Leucaspius Delineatus (Heckel, 1843), Elena V. Dzyuba, Yurij S. Bukin, Bakhtiar E. Bogdanov, Yulia P. Sapozhnikova, Natalia N. Denikina

Turkish Journal of Zoology

The common sunbleak (Leucaspius delineatus) is an invasive fish found in Siberian  water bodies, the trophic interactions and impact on local ecosystems of which  remain poorly understood. Traditional diet analyses are limited by the mechanical  damage to the prey. For the present study, therefore, we employed DNA  metabarcoding of the cytochrome c oxidase I (cox1) gene to analyze the digestive  tract contents of the common sunbleak obtained from Irkutsk Reservoir. Our analysis  revealed 53 operational taxonomic units (OTUs), with sequences of amphibiotic  insects (58.66%) and fish (34.10%) being the most prevalent. A significant proportion  of the fish DNA, including sequences …


Distribution Of Mussels In Two Intermittent Upland Streams Of The Arkansas Valley Ecoregion, A. A. Brady, K. B. Hecke, S. A. Drake, Z. R. Crain, K. Moles Jan 2026

Distribution Of Mussels In Two Intermittent Upland Streams Of The Arkansas Valley Ecoregion, A. A. Brady, K. B. Hecke, S. A. Drake, Z. R. Crain, K. Moles

Journal of the Arkansas Academy of Science

Freshwater mussels are facing an increasing need for conservation due to their declining populations. More data is needed on mussel distributions, especially in tributaries of large rivers to properly conserve and restore populations. Big Shoal Creek and Little Shoal Creek are two upland-tributaries of the Arkansas River (Lake Dardanelle) in which no records exist for freshwater mussel populations. We addressed this knowledge gap by sampling a total of 9 sites in Little Shoal Creek and 18 sites in Big Shoal Creek to determine the abundance and distribution of mussels in these streams. Mussels were sampled using a timed-search approach. A …


Erratum To “The Effect Of Using Cidr And Various Doses Of Pmsg As Well As Genistein On The Reproductive Characteristics Of Palu Fat-Tailed Sheep”, Mardiah Mangun, Suyadi Suyadi, Muhammad Nur Ihsan, Marjuki Marjuki Jan 2026

Erratum To “The Effect Of Using Cidr And Various Doses Of Pmsg As Well As Genistein On The Reproductive Characteristics Of Palu Fat-Tailed Sheep”, Mardiah Mangun, Suyadi Suyadi, Muhammad Nur Ihsan, Marjuki Marjuki

Jurnal Ilmu Ternak Universitas Padjadjaran

This is a correction for

DOI: https://doi.org/10.24198/jit.v22i1.38035

In the originally published version of this article, the citation in column 1, page 15, line 11 from the bottom, … Suharto et al. (2008), does not appear in the References. Furthermore, the following references:

Jainudeen, M., & Hafez, E. (1987). Reproductive failure in female. In E. Hafez (Ed.), Reproduction in Farm Animal (7th ed.). Lea and Febiger.

and

Jainudeen, M. R., & Hafez, E. S. E. (1987). Gestation, Prenatal Physiology, and Parturition. In E. Hafez (Ed.), Reproduction in Farm Animal (7th ed.). Lea and Febiger.

do not include letter codes (a …


Bioaugmentation Of Microorganisms On The Decomposition Of A Mixture Of Dairy Cattle Manure And Chicken Excreta As Solid Organic Fertilizer, Kirana Riyanto, Roni Ridwan, Ellin Harlia Jan 2026

Bioaugmentation Of Microorganisms On The Decomposition Of A Mixture Of Dairy Cattle Manure And Chicken Excreta As Solid Organic Fertilizer, Kirana Riyanto, Roni Ridwan, Ellin Harlia

Jurnal Ilmu Ternak Universitas Padjadjaran

Solid organic fertilizer efficiently utilizes livestock waste, with laying hen excreta providing the highest nitrogen (N) content among livestock manure. Combining laying hen excreta with dairy cow manure and fiber sources as a fertilizer base is expected to meet KEPMENTAN No. 261 of 2019 standards. To maintain essential nutrients (N, P, K), the fertilizer is enriched with Pseudomonas sp., Herbasirillum sp., and Streptomyces sp. This study aims to analyzing the effect of chicken excreta on macronutrient content (N, P, K), carbon (C) levels, C/N ratio, coliform presence, and microbial viability. The experiment followed a completely randomized design (CRD) with …


Effect Of Corn Flour Addition On The Physical And Chemical Quality Of Wedelia Trilobata (L) Hitchc Weed Silage For Ruminant Livestock Feed, Ajat Sudrajat, Retno Galuh Syaharani, Nur Rasminati, Wahyu Candra Saputra, Niken Astuti, Raden Febrianto Christi, Fazhana Ismail Jan 2026

Effect Of Corn Flour Addition On The Physical And Chemical Quality Of Wedelia Trilobata (L) Hitchc Weed Silage For Ruminant Livestock Feed, Ajat Sudrajat, Retno Galuh Syaharani, Nur Rasminati, Wahyu Candra Saputra, Niken Astuti, Raden Febrianto Christi, Fazhana Ismail

Jurnal Ilmu Ternak Universitas Padjadjaran

Research on the physical and chemical quality of weed silage with the addition of corn flour has been carried out. The research was carried out on November 30, 2024 – February 25, 2025 at the Animal Nutrition Laboratory of the Animal Husbandry Study Program, Mercu Buana Yogyakarta University and the Chem-Mix Bantul laboratory, Yogyakarta. The study used an experimental method with a complete random design (RAL) in a unidirectional pattern using 4 treatments, namely P0 (no treatment), P1 (1% corn flour), P2 (3% corn flour) and P3 (5% corn flour), then each treatment was replicated three times. In each treatment, …


Effects Of 1,25-Dihydroxyvitamin D3 Supplementation On Performance Of 60-Week-Old Layers, Edgen Geñoso, Listya Purnamasari, Joseph Olarve, Joseph Dela Cruz Jan 2026

Effects Of 1,25-Dihydroxyvitamin D3 Supplementation On Performance Of 60-Week-Old Layers, Edgen Geñoso, Listya Purnamasari, Joseph Olarve, Joseph Dela Cruz

Jurnal Ilmu Ternak Universitas Padjadjaran

The effects of 1,25 dihydroxyvitamin D3 supplementation on egg production, percent hen house, percent hen day, mortality rate and egg size on 60-week-old laying hens were studied. There were 5 treatment groups of layer hens where Treatment 1 served as control supplemented with commercial feed without vitamin D3, Treatment 2 as positive control supplemented with commercial feed and vitamin D3 HyD, which was already used by the poultry farm, Treatment 3 supplemented with commercial feed and Active D at an inclusion rate of 75 ppm per ton of feeds, Treatment 4 supplemented with commercial feed and Active D at an …


Fermentabilitas Dan Kecernaan Ransum Domba Yang Mengandung Kulit Buah Pisang Muli (In Vitro), Iman Hernaman Jan 2026

Fermentabilitas Dan Kecernaan Ransum Domba Yang Mengandung Kulit Buah Pisang Muli (In Vitro), Iman Hernaman

Jurnal Ilmu Ternak Universitas Padjadjaran

Kulit buah pisang Muli memiliki potensi sebagai bahan pakan sumber serat pengganti rumput lapang, namun saat ini penggunaannya masih terbatas. Penelitian bertujuan untuk mempelajari penggunaan kulit buah pisang Muli dalam ransum terhadap fermentabilitas dan kecernaan (in vitro). Penelitian menggunakan rancangan acak lengkap dengan 4 perlakuan ransum yang mengandung 10, 20, 30, dan 40% kulit buah pisang Muli. Data yang terkumpul dianalisis dengan menggunakan Uji Duncan. Penelitian menghasilkan data yang memberi petunjuk adanya pengaruh nyata (P3yang terendah yaitu berturut-turut sebesar 161,5 mM, 66,72%, 66,15% dan 1,94 mM. Hasil penelitian menyimpulkan bahwa penggunaan kulit buah pisang Muli dapat sebanyak 40% dapat digunakan …