Digital Commons Network^™

Design And Validation Of A Novel Patterned Microfluidic Culture Platform For Hipsc-Cm Maturation, Anisia Gabriela Țiplea

Dartmouth College Master’s Theses

Adult cardiomyocytes (CMs) are among the most challenging cells to culture in vitro, given their poor adherence to plastic culture wells and poor maturation outside the native extracellular matrix (Narkar et al., 2022). Human induced pluripotent stem cell-derived CMs (hiPSC-CMs) offer a viable alternative to study heart development and disease progression. While not comparable to adult CMs in their maturity (Narkar et al., 2022), they mimic the clinical phenotypes of heart failure and are more feasible to culture. Nevertheless, hiPSC-CMs require specialized culture conditions that cannot be achieved with 2D static culturing, which fail to replicate native tissue environments (X. …

Lean Service System Optimization In U.S. Automotive Maintenance Centers: A Time Study And Simulation-Based Approach To Reducing Service Cycle Time And Increasing Efficiency, Rakibul Hasan Sarker

All Graduate Theses, Dissertations, and Other Capstone Projects

The primary objective of this study is to measure the current service time at a U.S. automobile service center, with the aim of reducing waste and optimizing service operations through time study and simulation modeling. Inefficiencies in those service centers increase service time and labor costs, reduce service quality, and reduce workshop productivity, thereby increasing customer waiting time. In this study, real-world shop floor data were collected from a single service center, namely Jiffy Lube. Over the course of ten working days, 205 vehicle data points were acquired. Service time, bay time, and overall process time were computed and examined …

Early Stem Impressions, Student Engagement, And Readiness For Digitalization, Myron Sheu

Journal of International Technology and Information Management

This study examines how early impressions of science, technology, engineering, and mathematics (STEM) shape business students’ learning behaviors and, ultimately, their readiness for organizational digitalization. Focusing on gender differences, subgroup identities, and perceived obstacles, the analysis uses survey data processed through correlation matrices, regression models, and subgroup heatmaps to trace the relationship between initial attitudes toward STEM and subsequent engagement patterns. The findings reveal consistent links between positive early impressions and active participation in structured STEM activities, along with gender-based distinctions in action preferences. Subgroup analyses further uncover nuanced patterns where stereotypes or perceived barriers correspond with reduced engagement. Collectively, …

Does Digital Innovation Matter For Hospital Efficiency? Evidence From U.S. Hospitals, C. Christopher Lee, Shihui Fan, Jung Young Lee, David W. Hwang

Journal of International Technology and Information Management

Purpose – This study examines the impact of digital innovation on hospital performance, providing evidence to guide healthcare administrators and policymakers in making informed decisions regarding digital investment.

Design/Methodology/Approach – Using data from the 2020 American Hospital Association (AHA) U.S. Hospital Survey and the 2019 AHA Information Technology Survey, we empirically analyze the relationship between five dimensions of digital innovation—automation, cybersecurity, telehealth, health information exchange (HIE), and IT spending—and three efficiency indicators: occupancy rate, capacity productivity, and manpower productivity.

Findings – The results show that digital innovation has varying effects on hospital efficiency. Automation is positively associated with capacity and …

The Crowdfunding Paradox In Crisis: Rising Funder Demand Vs. Declining Entrepreneur Supply, Dan Liu, Guangzhi Shang, Cynthia Fan Yang

Journal of International Technology and Information Management

This study investigates how the crowdfunding marketplace responds to major crises, focusing on behavioral shifts among funders and entrepreneurs. Results show a dual impact on platform dynamics. On the demand side, funders become more engaged, with notable increases in the number of backers, average contributions, and total pledge amounts. This heightened activity suggests stronger altruistic motivations, as individuals view crowdfunding as a way to support others during difficult times. On the supply side, however, entrepreneurs act more cautiously, leading to a decline in new project launches. This drop likely reflects increased risk aversion and uncertainty as creators navigate volatile conditions. …

Adaptive Self-Attention For Enhanced Segmentation Of Adult Gliomas In Multi-Modal Mri, Evan P. Savaria, Jiangwen Sun

Computer Science Faculty Publications

Every year there are an estimated 80,000–90,000 new glioma cases, highlighting the need for reliable imaging-based decision support. Although deep learning has improved tumor sub-region segmentation, many state-of-the-art models fail to fully capture complementary information across T1, T1Gd, T2, and FLAIR MRI modalities and often operate as “black boxes,” limiting physician trust when precise delineation is critical for surgical planning, radiation targeting, and treatment monitoring. To address these limitations, we propose AIMS, an Adaptive Integrated Multi-Modal Segmentation framework that maintains modality-specific feature streams and employs adaptive self-attention within a hierarchical CNN-Transformer architecture to prioritize and fuse multi-modal MRI features. We …

Susceptibility To High-Fidelity Misinformation: An Eye-Tracking Analysis, Yasasi Abeysinghe, Gavindya Jayawardena, Enkelejda Kasneci, Sampath Jayarathna

Computer Science Faculty Publications

With the rise of online misinformation and AI-generated text, understanding human perception of news truthfulness is critical. In this study, we examine visual attention and cognitive processing using eye-tracking measures as individuals read fake and real news articles sharing nearly identical structure and imagery, differing only in subtle textual changes. Using the public FakeNewsPerception dataset, we analyze advanced gaze measures, including scanpaths, AOI transitions, and luminance-corrected pupil measures, beyond basic gaze features, in relation to news truthfulness and perceived believability. Results show that, given the high fidelity of the fake news, readers exhibited comparable visual scanning patterns, attention allocation across …

Distributed Semi-Speculative Parallel Anisotropic Mesh Adaptation, Kevin Garner, Polykarpos Thomadakis, Nikos Chrisochoides

Computer Science Faculty Publications

This paper presents a distributed memory method for anisotropic mesh adaptation that is designed to avoid the use of collective communication and global synchronization techniques. In the presented method, meshing functionality is separated from performance aspects by utilizing a separate entity for each - a multicore cc-NUMA-based (shared memory) mesh generation software and a parallel runtime system that is designed to help applications leverage the concurrency offered by emerging high-performance computing (HPC) architectures. First, an initial mesh is decomposed and its interface elements (subdomain boundaries) are adapted on a single multicore node (shared memory). Subdomains are then distributed among the …

Extrusion-Based Additive Manufacturing Of Magnetic Heat Exchange Structures For Caloric Applications, Turab S. Rizvi

UROP Posters

Developing sustainable, high-efficiency cooling technologies is vital to addressing 21st century energy challenges. This research focuses on magnetic refrigeration, an environmentally friendly cooling method utilizing the magnetocaloric effect to regulate temperature using magnetic fields. This approach offers greater energy efficiency than conventional vapor-compression systems by eliminating harmful refrigerants. The critical component is the regenerator, made of magnetocaloric material and transfers heat between the magnetic material and a fluid through parallel channels. Traditional designs such as packed beds of particles are prone to particle segregation, creating an undesirable pressure drop. The main goal of our research was to fix those flaws …

Estimating Sediment Properties Using A New Source Level Function For Wind-Driven Underwater Sound Derived From Long-Term Archival Data, S Bruce Martin, Martin Siderius

Electrical and Computer Engineering Faculty Publications and Presentations

Wind-driven breaking waves generate the background sound throughout the ocean. An accurate source level for wind-driven breaking waves is needed for estimating the ambient sound levels needed for sound exposure modeling, environmental assessments, and assessing the detection performance of sonars. Previous models applied a constant roll-off of sound levels at -16 dB/decade at all wind speeds, and these models' source levels were flat at frequencies below ∼1000 Hz due to a lack of measurements. Here, we analyzed 16 long-term archival datasets with limited anthropogenic sound sources to estimate the wind-driven source level down to 100 Hz. We estimated the site-specific …

Quantifying Hemodynamics In Implantable Cardiac And Renal Support Devices Using Computational Modeling, Alexander D. De Oliveira

Summer Research Program Abstracts

No abstract provided.

Scalar Source Localization Using Multi-Sensor Domains Of Dependence In Turbulent Channel Fow, Zejian You, Xiaowei Zhu, Qi Wang

Mechanical and Materials Engineering Faculty Publications and Presentations

Tracking hazardous events such as wildfire smoke, coastal oil spills, or chemical releases in natural environments is complicated by turbulent dispersion and molecular diffusion. This study presents a method to localize pollutant sources rapidly and accurately using infinite time-averaged measurements from a multi-sensor network, leveraging the duality between mean forward and adjoint scalar fields. The forward-adjoint duality states that measurements at the sensor (forward feld) are equal to the adjoint field at the source, providing crucial spatial information about the source. Consequently, the adjoint scalar fields can be interpreted as the domain of dependence for the sensor observations [1, 2]. …

Land Use And Land Cover Simulation Via Integrated Modelling With Gis Techniques For Sustainable Land Utilization Development In The Northeast Khong Subwatershed Of Thailand, ฺBanchongsak Faksomboon, Thipphaphone Keoviyavong

Applied Environmental Research

Land utilization is an important indicator of socioeconomic and environmental changes caused by both natural and man-made factors. Land use and land cover (LULC) simulation is a critical tool for monitoring and predicting LULC and is essential for sustainable development, land resource management and planning. The cellular automata (CA) Markov model is the basis for the current study’s prediction of LULC changes in the Northeast Khong Sub Watershed (NKSW). Landsat data from 2013 to 2023 were used to investigate LULC classification and determine the spatiotemporal distributions of LULC. In addition, LULC data from 2013 and 2023 were used to generate …

Reduction Of Cr(Vi) With Infrared Light And Chemical Adsorption Of Cr(Iii) By A God-Crown/Bentonite Composite For Electroplating Waste Remediation, Andre Taufik Kurniawan, Muhammad Djoni Bustan, Sri Haryati

Applied Environmental Research

Heavy metal pollution, particularly chromium (Cr) from electroplating industrial waste, has severely threatened environmental quality and human health. This study aims to develop a composite adsorbent material based on bentonite and god crown biomass capable of removing chromium ions from liquid waste through a combination of reduction and adsorption mechanisms. The god crown/bentonite (GC/Bt) composite was synthesized at a mass ratio of 2:1 and calcined at 900°C. FTIR characterization revealed active functional groups (–OH, C=O, Si–O, and Al–O–Si), whereas BET analysis revealed a mesoporous structure (surface area 31.12 m2 g-1, pore diameter 4.37 nm) suitable for ion diffusion. The reduction …

Fabrication Of Urea With Amorphous Silica To Increase Rice Growth In Saline Soils, Thi Ha Chi Nguyen, Thi Hang Thuc Ha, Minh Phuong Nguyen, Ngoc Chuc Pham, Quang Bac Nguyen, Nguyen Huy Tuan Do, Ngoc Nhiem Dao, Trung Kien Nguyen

Applied Environmental Research

In recent decades, the decrease in rice cultivation areas in Vietnam, particularly in the Mekong River Delta, caused by climate change and soil salinization, has posed serious challenges for sustainable development. In addition to irrigation and agronomic practices, fertilizers that sustain rice growth under saline conditions play a crucial role in improving crop productivity. Amorphous silica has been reported to increase plant tolerance to drought, salinity, and heavy metal stress. In this study, nanosilica-coated urea (UCS) fertilizers were synthesized by coating urea granules with 1–5 wt% amorphous silica. The products were characterized by SEM, XRD, FTIR, TG‒DSC, and EDX to …

Heavy Metals And Organic Carbon In Sediments Of Seagrass Sediments Of Trang Province, Thailand, Siriporn Pradit, Pornthep Wirachwong, Thongchai Nitiratsuwan, Sujaree Bureekul, Supraewpan Lohalaksanadech, Thawanrat Kobkeatthawin, Monticha Jirajaras, Prakrit Noppradit, Sanya Sirivithayapakorn

Applied Environmental Research

In this study, the accumulation of heavy metals (Cd, Cr, Cu, Fe, and Pb) in water, suspended sediments, sediments, and seagrass in Kalase Bay, Trang Province, Thailand, during the 2024 dry season was investigated. These findings indicate that the enrichment factor (EF) for all the metals was less than 1, suggesting that anthropogenic contamination is not a significant concern in the area. The translocation factor (TF) values were less than 1 for all the metals except Cu, whose TF was greater than 1; however, these values were not statistically significant, indicating limited phytoextraction capacity. The bioconcentration factor (BCF) values for …

Spatial Modeling Of Natural Disaster Risk By Integrating Hazard, Vulnerability, And Exposure Factors Using Geospatial Techniques : Evidence From Mueang Tak District, Thailand, Suphatphong Ruthamnong

Applied Environmental Research

This study presents a comprehensive multihazard risk assessment for Mueang Tak District, Thailand, that integrates hazard, vulnerability, and exposure (H-V-E) dimensions. By utilizing geographic information systems (GIS) and remote sensing, the analytic hierarchy process (AHP) was employed to prioritize critical risk factors. GIS analysis integrated multisource spatial data, including Landsat 9 and Sentinel-2 imagery, CHIRPS precipitation, and SRTM-derived topography, while AHP weights were established on the basis of expert judgment and socioeconomic indices such as the relative wealth index (RWI) and population statistics. The results delineate distinct spatial risk clusters: high landslide potential is concentrated in the steep terrain of …

Carbon Stock Assessment In Sonneratia Apetala Afforested Mangroves : A Case Study From Cox’S Bazar, Bangladesh, Mohammad Ismail, Sayed Abu Johany, Tanmoy Dey, Zakia Sultana Teasa, Trishna Das, Prabal Barua, Tonima Hossain, Sajib Ahmed

Applied Environmental Research

Sonneratia apetala is a key species for mangrove afforestation projects in Bangladesh and plays a crucial role in ecosystem restoration and carbon sequestration. The research on how the total carbon stock (TCS) varies across S. apetala plantations in Cox’s Bazar remains limited. Thus, in this study, the biomass and soil carbon stock were quantified across nine S. apetala afforested sites in Cox’s Bazar to assess spatial variation and influencing factors. The total biomass carbon (TBC) was calculated by summing the aboveground (AGBC) and belowground (BGBC) biomass carbon, while the soil organic carbon stock (SOCS) was determined from the 0–40 cm …

Seasonal Wastewater Monitoring And Quantitative Microbial Risk Assessment Of Escherichia Coli In A University Wastewater System, Pathum Thani, Central Thailand, Natsima Tokhun, Natagarn Tongphanpharn, Weerawat Ounsaneha, Montip Jankeaw, Wiriyabhorn Klomsungcharoen, Patsara Wongsudi, Yawanart Ngamnon, Cheerawit Rattanapan, Kwang Mo Yang

Applied Environmental Research

In this study, the physicochemical properties of wastewater were characterized, and a quantitative microbial risk assessment (QMRA) of E. coli was conducted in the wastewater treatment system of the Faculty of Science and Technology, Valaya Alongkorn Rajabhat University, under the Royal Patronage, Pathum Thani, Thailand (VRU-SciTech). This study was conducted because the current water-quality assessment does not include the QMRA or evaluate the occupa-tional and incidental public risk of infection. Over a one-year monitoring period, this study quantified wastewater generation (~6.09 L person-1 day-1; ~3.21 × 103 m3 year-1) and analyzed its physicochemical parameters and E. coli concentrations. High concentrations …

Evaluation Of Soil Moisture Content, Ph, And Dominant Microorganisms In Crude Oil–Contaminated Soil Treated With Cow Dung, Indole-3-Acetic Acid (Iaa), And Simulated Microgravity, Amenze Ovenseri, Tawari-Fufeyin P.

Applied Environmental Research

Crude oil negatively affects soil physicochemical properties and microbial activity, thereby hindering plant growth and posing notable environmental and agricultural issues. The combined effects of cow dung, indole-3-acetic acid (IAA), and simulated microgravity on the recovery of soil degraded by crude oil were explored using Zea mays as the test plant. Soil was contaminated with crude oil at different concentrations (0%, 1%, 3%, and 5% v/w), with each concentration comprising eight treatments: cow dung, Zea mays seeds exposed to microgravity, and IAA alone or in combination. Changes in plant height, soil pH, soil moisture content, and soil microbial diversity were …

Engineering Disorder, Defects, And Electrical Transport For High-Performance Thermoelectric Fe2val Heusler Alloys, James Russell Taylor Iv

Dartmouth College Ph.D Dissertations

Fe₂VAl is a promising low-temperature thermoelectric material for waste-heat energy conversion because it is easily processed and comprised of earth-abundant, non-toxic, and low-cost elements. However, viability for applications faces two major challenges: high thermal conductivity and low p-type Seebeck coefficients. This primarily experimental work aims to address these issues through extrinsic and self-doping, point-defect and disorder generation through thermal and electrical processing, disordered and metastable phase composition quantification, and comparison of transport measurements to modeled electronic features.

An accessible phase quantification method was developed for bulk Fe₂VAl using laboratory X-ray diffraction equipment to compare thermoelectric properties …

Photothermal Excitation And Optical Interferometric Readout Of Mos2 Nanomechanical Resonators, Sadia Afrin

Graduate Studies Theses and Dissertations 2026

Two-dimensional (2D) materials have emerged as promising candidates for nanoelectromechanical systems (NEMS) due to their exceptional mechanical, optical, and electrical properties. Among these materials, molybdenum disulfide (MoS2) has attracted considerable interest for nanomechanical resonator applications because of its low mass density, high mechanical strength, and semiconducting nature. This thesis presents the fabrication, theoretical modeling, and experimental characterization of suspended MoS2 drumhead resonators. The devices were fabricated by mechanically exfoliating MoS2 flakes from bulk MoS2 crystals and transferring selected flakes onto pre-patterned substrates using a dry-transfer process. Mechanical resonance was excited through photothermal actuation using a modulated blue laser, while device …

Pseudo-Boiling Of Supercritical Co2 In A Parallel-Flow Microchannel And A Micro-Jets Impingement Device And Single-Phase And Two-Phase Heat Transfer Of Subcritical Co2 Jets, Pranzal Ahmed

Graduate Studies Theses and Dissertations 2026

Carbon dioxide (CO2) is gaining attention as a low-toxicity, zero-ozone-depletion refrigerant with a global warming potential of 1, making it an attractive alternative to synthetic HFCs/HFOs. Near its critical point, CO2's thermophysical properties change sharply with small shifts in temperature and pressure — a behavior that can be exploited to enhance heat transfer in trans-critical power cycles and electronics cooling. This dissertation experimentally investigates heat transfer during the pseudo-boiling of supercritical CO2 in a parallel-flow microchannel and a micro-jet impingement device, alongside CO2 flow boiling and single-phase water heat transfer in micro-jet impingement. Using microfluidic devices instrumented with embedded resistance …

Effects Of Back-Pressure On Pseudo-Shock Systems, Emil C. Alunno

Graduate Studies Theses and Dissertations 2026

The isolator of a scramjet engine houses a pseudo-shock, a compressive flow structure that raises the static pressure and decelerates the incoming supersonic flow for efficient combustion while shielding the inlet from the elevated pressure downstream. Under sufficient back pressure the leading shock bifurcates and forms a shock train followed by a shockless mixing region, and the resulting system oscillates even under nominally steady conditions; this unsteadiness distorts the flow, can drive the pseudo-shock out of the isolator and unstart the inlet. This thesis experimentally examines how a pseudo-shock in a constant-area isolator at a measured entrance Mach number of …

Numerical Investigation Of Reacting Flow In Pmma-Fueled Solid Fuel Scramjet Combustors Under Experimental Test Conditions, Hunter Bassett

Graduate Studies Theses and Dissertations 2026

A simplified steady RANS-based numerical study of reacting flow in solid-fuel scramjet combustors is presented to evaluate the ability of commercial CFD frameworks to reproduce key features observed in experimental test sections. The work focuses on solid PMMA fuel in two supersonic combustor configurations: a cavity-assisted flameholding combustor and a variable-angle diverging combustor. The cavity combustor is analyzed as a baseline case and results are compared directly with experimental data. Three combustor geometry states corresponding to ignition, early-burning, and steady-burning conditions are investigated. Meshes are assessed through a systematic grid refinement method to establish grid independence. A novel variable-angle diverging …

Connecting The Existing Fiber Infrastructure To The Future With Antiresonant Hollow Core Fibers, Timothy Bate

Graduate Studies Theses and Dissertations 2026

Optical fiber systems based on solid-core silica waveguides underpin modern telecommunications, high-power laser delivery, precision sensing, and coherent optical systems. However, nonlinear effects, material absorption, and thermal limitations within silica increasingly constrain further scaling in both optical power and transmission performance. Antiresonant hollow-core fibers provide a promising alternative by guiding light predominantly in air, substantially reducing nonlinear interactions, latency, and optical damage while enabling transmission regimes inaccessible to conventional solid-core fibers. Despite rapid advances in antiresonant hollow-core fiber attenuation and power handling, one of the largest remaining barriers to widespread adoption is reliable integration with the existing solid-core fiber ecosystem. …

Flow Field Characterization Of The Hyperreact Vitiated Hypersonic Wind Tunnel, Erik R. Fernandez

Graduate Studies Theses and Dissertations 2026

Reliable interpretation of hypersonic ground-test data requires knowledge of the thermochemical state delivered to the test section, especially in combustion-heated facilities where the gas is chemically altered before nozzle expansion. This thesis investigates the HyperReact vitiated hypersonic wind tunnel using the effective specific-heat ratio, γeff, as an experimentally inferred indicator of the coupled chemical and gas-dynamic behavior of hydrogen-air vitiated flow. HyperReact produces high stagnation temperatures through hydrogen-air combustion before expanding the mixture through interchangeable converging-diverging nozzles. During this expansion, temperature-dependent specific heats, molecular-weight changes, finite-rate chemistry, and internal energy relaxation can modify the relationship between Mach number, pressure ratio, …

Minimizing Performance Overheads For Crash-Consistency In Disaggregated Persistent Memory, Khan Shaikhul Hadi

Graduate Studies Theses and Dissertations 2026

Compute express link (CXL) enables persistent memory disaggregation with memory pooling and hardware managed multi-host memory sharing capability, resulting in better resource utilization, increased scalability. Persistency-aware applications need to manage crash consistency across the system which results in significant performance overhead. This dissertation systematically investigates performance overhead to achieve crash consistency in disaggregated persistent memory and proposes solutions to enable persistency-aware application scaling for distributed system. First, we study persistent parallel programming to scale computation capability beyond single processor and determine the underlying hardware limitation to adopt lock-free data structure. We propose hardware support to design durable atomic instruction (DAI) …

Integrated Optical Probes For Confocal Scanning Imaging And Adjustable Coherent-Gated Dynamic Sensing, Yonglin Huang

Graduate Studies Theses and Dissertations 2026

Optics and photonics have been one of the most important sciences and technologies that impact modern human life in a big way. For example, fiber-optics for communications and artificial intelligence. Optical probes are critical components for optical imaging and optical sensing technologies that have been actively researched and developed in the past decades. Advanced fiber-optic sensor probes with smaller size, better performance, lower noise, higher photon efficiency, rapid sensing time, and lower cost are needed in many applications, such as nanoscale material science, chemistry, and biomedical fields, etc.  In this project, new fiber-optic sensor probe technologies and integrated micro-optic devices …

Experimental And Computational Characterization Of A Rotorcraft-Tiltrotor Model Using Morphing Wings For Whirl Flutter Instability, Darrell Nieves Lugo

Graduate Studies Theses and Dissertations 2026

Tiltrotor rotorcraft configurations combine the capabilities of vertical and forward flight, offering a crucial and advantageous design for maximizing the operational flight envelope. This versatility enables broad adaptability across numerous designs and platforms, including unmanned aerial vehicles (UAVs), micro-air vehicles (MAVs), and vertical take-off and landing (VTOLs) aircraft. However, propeller-based aircraft are susceptible to an aeroelastic instability at high flight speeds known as whirl flutter. This instability phenomena is a crucial research task and problem to investigate, as with advances in manufacturing and vehicle designs, these can yield new rotorcraft formats capable of advancing the flight envelopes at higher cruise …