Digital Commons Network^™

Using Peptide Design To Engineer Polyelectrolyte Complex Biomaterials, Sara Tabandeh

Electronic Theses and Dissertations, 2020-2023

The self-assembly of oppositely charged polymers provides a versatile platform to design materials for diverse applications in biology and medicine. Electrostatically-driven phase separation of oppositely charged polymers in aqueous solution gives rise to the formation of a polymer-rich phase called a polyelectrolyte complex (PEC). PECs can be in the form of liquid droplets (complex coacervates) or amorphous solid precipitates. Unlike synthetic polymers, peptides are good candidates for developing tailor-made formulations and structure-property relationships due to their biocompatibility, precise control over sequences, and ability to program hydrogen bonding interactions. However, little is known about the effect of combining additional molecular interactions …

Study Of Mos2/High-K Interface And Implementation Of Mos2 Based Memristor For Neuromorphic Computing Applications, Durjoy Dev

Electronic Theses and Dissertations, 2020-2023

The scientific world is witnessing an unprecedented triumph of artificial neural network (ANN)- a computing system inspired by the biological neural network. With the enthralling quest for Internet of Everything (IoE), it is expected to have an unparalleled dominance of ANN in our day-to-day life. In recent times, memristor has come as an emerging candidate to realize ANN through emulating biological synapse and neuron behavior. Molybdenum disulfide (MoS2), one well-known two-dimensional (2D) transition metal dichalcogenides (TMDCs), has drawn interest for high speed, flexible, low power electronic devices since it has a tunable bandgap, reasonable carrier mobility, high Young's modulus, and …

A Comparative Study Of Machine Learning-Based Approach For Network Traffic Classification, Kien Trang, An Hoang Nguyen

Knowledge Engineering and Data Science

Internet usage has increased rapidly and become an essential part of human life, corresponding to the rapid development of network infrastructure in recent years. Thus, protecting users’ confidential information when joining the global network becomes one of the most significant considerations. Even though multiple encryption algorithms and techniques have been applied in different parties, including internet providers, and web hosting, this situation also allows the hacker to attack the network system anonymously. Therefore, the significance of classifying network data streams to improve network system quality and security is attracting increasing study interests. This work introduces a machine learning-based approach to …

Cnn Based Face Recognition System For Patients With Down And William Syndrome, Endang Setyati, Suharyono Az, Subroto Prasetya Hudiono, Fachrul Kurniawan

Knowledge Engineering and Data Science

Down syndrome, also known as trisomy genetic condition, is a genetic disorder that affects many people. Williams syndrome is a hereditary disorder that can affect anyone at birth. It marks medical and cognitive issues, such as cardiovascular illness, developmental delays, and learning impairments. This is accompanied by exceptional verbal abilities, a gregarious attitude, and a passion for music. Down syndrome and William Syndrome are both genetic illnesses. However, it can be distinguished from the arrangement of chromosome 21. Down syndrome and William syndrome can also be identified by recognizing faces, or facial characteristics, such as observing particular facial features. Therefore, …

Quaternary Ammonium Compounds As Precursors To Disinfection Byproducts, Padmanabhan Krishnaswamy

UNLV Theses, Dissertations, Professional Papers, and Capstones

Disinfection of drinking water is crucial for providing a safe potable water supply. Some of the most common disinfectants employed are chlorine, chloramines and ozone. While these disinfectants successfully inactivate pathogenic microorganisms, they simultaneously react with inorganic or organic precursors to form toxic byproducts, most commonly referred to as disinfection byproducts (DBPs). While there is a wide variety of organic matter and disinfection byproducts known, in this study we have looked into the potential of certain quaternary ammonium compounds (QACs) to act as precursors to form DBPs, namely trihalomethanes (THMs), haloacetonitriles (HANs) and nitrosamines.

The ubiquitous nature of QACs in …

Effect Of Hydrogen Peroxide On Algae And Microcystin In Control And Lake Waters, Tatiana Castillo Hernandez

Biological and Agricultural Engineering Undergraduate Honors Theses

Cyanobacteria are photo-autotrophic organisms with a worldwide distribution, which can result in Harmful Algal Blooms (HABs) producing toxins. One of the most common strains of cyanobacteria is Microcystis, which produces the most abundant cyanotoxin, microcystin. In this study, we analyzed the effect of H₂O₂ on algae and microcystin using both lake and reagent grade water. The first objective was to determine the effect of H₂O₂ on algae and cyanobacteria in lake water that was nutrient enriched. The second objective was to detect the effect of H₂O₂ at oxidizing microcystin in …

Using Dynamic In Vivo Kinematics For Subject-Specific Calibration Of Knee Ligament Parameters, Stephen Nelson

Boise State University Theses and Dissertations

In vivo clinical studies are the optimal way to investigate the biomechanical outcomes of new prosthetic devices. This particular style of testing can be difficult and, in certain cases, unethical to perform. The testing of unproven devices, surgical techniques, and materials put patients at risk from unanticipated outcomes in how these devices respond to the in vivo environment and patient-specific loading conditions. Biomechanical computational models were developed to provide validation to new devices prior to clinical testing. Computational models for use in optimizing knee prosthetics frequently include ligament representations, but these representations have inherent uncertainty due to wide intersubject variation …

Social Media Influencers (Smis) In Context: A Literature Review, Charles Alves De Castro, Isobel O'Reilly Dr, Aiden Carthy

Articles

This review focused on three main areas, "Social Media Influencers (SMIs) in Context, The Impact of SMIs on Adolescents, and Consumer Behaviour in a Digital Era – Generation Z in Perspective". This article aims to further the overall understanding of SMIs and outlines the impact of SMIs on adolescents‘ lives. Thus, the main objective of this literature review is to raise awareness within the marketing field about the influence of social media influencers on adolescents and how brands promote their products and content through social media influencers. The review comprised a regular search using electronic journal databases and secondary data …

Effects Of Aging On Mouse Rotator Cuff Tendon Biomechanics, Chinmay Sagar Patwardhan

Bioengineering Theses - Archive

Rotator cuff tendon injuries and tear are caused by overuse, falling, or other accidents, and are often associated with old age. The severe injuries and tear can be debilitating and require nonsurgical treatment for partial tear and arthroscopic surgery for complete tear. The frequent location of injuries and tear are at the enthesis region, the interface where the tendon tissue gradually hardens and merges into the bone. Although aging has been identified as an important factor for rotator cuff tendon injuries and tear, how the mechanical properties of the bone-tendon complex evolve along with age is still a knowledge gap. …

A Linear Dynamical Perspective On Epidemiology: Interplay Between Early Covid-19 Outbreak And Human Mobility, Shakib Mustavee

Electronic Theses and Dissertations, 2020-2023

This research investigates the impact of human activity and mobility (HAM) in the spreading dynamics of an epidemic. Specifically, it explores the interconnections between HAM and its effect on the early spread of the COVID-19 virus. During the early stages of the pandemic, effective reproduction numbers exhibited a high correlation with human mobility patterns, leading to a hypothesis that the HAM system can be studied as a coupled system with disease spread dynamics. This study applies the generalized Koopman framework with control inputs to determine the nonlinear disease spread dynamics and the input-output characteristics as a locally linear controlled dynamical …

Long Haulers: The Us Airline Industry And Moving Forward From The Covid-19 Pandemic, James Norman

Aviation Faculty Publications

No abstract provided.

Evaluation Of A Novel Approach For Assessing Biological Activity In Agricultural Soils, Karla Melgar

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Soil health is a key factor impacting soil resilience and fertility in crop production systems. Favorable soil physical and biological conditions facilitate plant nutrient absorption and nutrient cycling. Demonstrating to farmers the impacts and changes in soil biological activity under different soil management practices has been a challenge due to the limited availability of inexpensive tools for quantifying this component of soil health. The primary goal of this study was to present a simple and readily accessible tool for evaluating soil biological activity to promote the use of organic amendments in crop fields. Research plots were established in two studies …

High-Frequency Unmanned Aircraft Flights For Crop Canopy Imaging During Diurnal Moisture Stress, Suresh Pradhyun Kashyap

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Previous research has used unmanned aerial vehicle (UAV) technology for calculating CWSI (Crop Water Stress Index) values in the context of irrigation scheduling. Typically, these estimations were taken at one time of day, usually near shortly after solar noon. A significant limitation with these CWSI values is that the UAV thermal imagery captured at this point in time can be affected by various factors like atmospheric air temperature, solar radiation, wind speed, relative humidity, and other micrometeorological disturbances in the air. In order to address these temporal effects, high-frequency UAV flights were conducted over different daylight hours to analyze and …

Coal Fly Ash Beneficiation For Reuse And Removal Of Boron, Cadmium, Chromium, Copper, And Selenium In Wastewater Treatment., Joseph E. Cahill

Electronic Theses and Dissertations

New regulations on coal-fired power plants make previously used wastewater treatment methods aimed to remove heavy metals obsolete. Therefore, there has been increased interest and investment into new technologies to treat coal-fired power plants effluent in the past few years. Traditionally, heavy metal removal technologies have been broken into three categories: physical, chemical or biological. However, with new regulations, each category by itself does not offer an ideal solution to removing acceptable concentrations of heavy metals found in the effluents at the coal-fired power plants. Here we report a novel proof-of-concept utilizing adsorption through ion-exchange/co-precipitation - chemical and physical - …

Scalable Synthesis Of Alumina Nanowires By Wet Chemical Method., Luis N Moreno

Electronic Theses and Dissertations

To satisfy an increasing demand for large-scale processes for producing alumina nanomaterials, a wet chemical method was evaluated. A potassium salt precursor was combined with aluminum to produce alumina – based nanowires. Compared with current methods such as thermal oxidation, sol-gel, and laser ablation, this method is highly scalable due to relatively low energy requirements and the ability to carry out the primary reaction under ambient conditions. The nanowire samples were evaluated using SEM, XRD, BET, and TEM to confirm morphology, phases present, and surface area. A porous nanowire structure was confirmed which has a BET surface area of 324.6 …

Update Of Multicellular Data Standard To Match Physicell "Compact" Output., Reid A Honeycutt

Electronic Theses and Dissertations

In the field of multicellular biology, it is currently very difficult for researchers to share digital data, due to a lack of standards for said data. Each laboratory will collect data from a particular project, which will describe only the features relevant to their research, and then present that data using written descriptions, charts, graphs, and images. This makes it difficult for the data produced by these studies be leveraged in other research efforts by scientists studying similar phenomena. An open-source, universal standard that attempts to meet this need is the MultiCellular Data Standard (MultiCellDS). MultiCellDS is described as a …

Design Of A 300cm2 Pemfc Stack With Force And Cfd Simulation To Optimize Flow Channels, Gasket Design, And Clamping Forces., Robert M. Ench

Electronic Theses and Dissertations

Proton exchange membrane fuel cells are important to the future of green energy as hydrogen can be made with green technologies and store energy for later use. Fuel cells can efficiently convert the hydrogen to electricity as needed. This study uses Solidworks simulation to make design improvements to the fuel cell before the prototype build stage of testing; this saves money and time by reducing the prototype builds needed.

In this study, a multi-channel serpentine design with two outlets versus a single outlet is evaluated using CFD to investigate pressure drop. Lower pressure drops are desirable as less energy input …

Solvent Engineering Of Molybdenum Disulfide Electrocatalyst For Hydrogen Evolution., Robert Carl Spalding

Electronic Theses and Dissertations

Energy is at an exponentially growing demand, and to keep up with these demands new technologies for renewable energy have received increased attention. Hydrogen plays a vital role in water electrolysis and fuel cells, as the hydrogen evolution reaction (HER) is the main step water splitting process. Most of the current electrocatalysts for HER are dominated by platinum and other precious metals due to their low over-potential and small Tafel slope, however, they are extremely costly. For this reason, cost-effective non-precious metal catalysts must be developed. Transition metal dichalcogenides, such as molybdenum disulfide (MoS2), are abundant and have recently shown …

Computational Modeling Of 3d-Printed Lactobacillus-Antibiotic Scaffolds For Bacterial Vaginosis., Veeresh P. Rai

Electronic Theses and Dissertations

The standard treatment for bacterial vaginosis (BV) is currently antibiotics, such as metronidazole, clindamycin, or tinidazole. These antibiotics are highly effective in getting rid of bacteria in the female reproductive tract (FRT); however, there are some bacteria that provide benefits to the FRT which also get expunged. While there are many strains of bacteria that play a beneficial role in the FRT, lactobacilli are among the most important. These bacteria are responsible for maintaining a healthy environment in the FRT via pH regulation by lactic acid metabolism. Antibiotics eliminate all bacteria from an environment, including lactobacilli, and as a result, …

Dreams Of Molecular Beams: Indium Gallium Arsenide Tensile-Strained Quantum Dots And Advances Towards Dynamic Quantum Dots (Moleculare Radiorum Somnia: Indii Gallii Arsenicus Tensa Quanta Puncta Et Ad Dinamicae Quantae Puntae Progressus), Kevin Daniel Vallejo

Boise State University Theses and Dissertations

Through the operation of a molecular beam epitaxy (MBE) machine, I worked on developing the homoepitaxy of high quality InAs with a (111)A crystallographic orientation. By tuning substrate temperature, we obtained a transition from a 2D island growth mode to step- ow growth. Optimized MBE parameters (substrate temperature = 500 °C, growth rate = 0.12 ML/s and V/III ratio ⩾ 40) lead to growth of extremely smooth InAs(111)A films, free from hillocks and other 3D surface imperfections. We see a correlation between InAs surface smoothness and optical quality, as measured by photoluminescence spectroscopy. This work establishes InAs(111)A as a platform …

Role Of The Nuclear Envelope In The Mechanoregulation Adipogenesis, Matthew H. Goelzer

Boise State University Theses and Dissertations

Mechanical signals are known regulators of mesenchymal stem cell (MSC) fate, regulating their differentiation into osteoblasts, chondrocytes, and adipocytes. These relevant mechanical signals reach to nucleus through nuclear envelope proteins such as Lamin A/C and the Linker of the Nucleoskeleton and Cytoskeleton (LINC) complexes. Within the context of bone, clinically relevant mutations of Lamin A/C and the LINC complexes have been shown to alter adipogenic and osteogenic MSC differentiation patterns, suggesting that that nucleo-cytoskeletal connectivity provided by nuclear envelope is important in regulating MSC fate. Using MSC adipogenesis as a model of MSC mechanical regulation, the goal of this work …

Single-Walled Carbon Nanotubes Inhibit Trpc4-Mediated Muscarinic Cation Current In Mouse Ileal Myocytes, Lina T. Al Kury, Dimitrios Papandreou, Vasyl V. Hurmach, Dariia O. Dryn, Mariia I. Melnyk, Maxim O. Platonov, Yuriy I. Prylutskyy, Uwe Ritter, Peter Scharff, Alexander V. Zholos

All Works

Single-walled carbon nanotubes (SWCNTs) are characterized by a combination of rather unique physical and chemical properties, which makes them interesting biocompatible nanostruc-tured materials for various applications, including in the biomedical field. SWCNTs are not inert carriers of drug molecules, as they may interact with various biological macromolecules, including ion channels. To investigate the mechanisms of the inhibitory effects of SWCNTs on the muscarinic receptor cation current (mICAT), induced by intracellular GTPγs (200 µM), in isolated mouse ileal myocytes, we have used the patch-clamp method in the whole-cell configuration. Here, we use molecular docking/molecular dynamics simulations and direct patch-clamp recordings of …

Effects Of Il-10 On Local Cell Populations And Functional Recovery Following Vml Injury, Zain Blackwell

Biomedical Engineering Undergraduate Honors Theses

Volumetric muscle loss (VML) injuries are prevalent in both military personnel suffering from battlefield related incidents, and civilians following severe motor accidents. Despite its prevalence, VML has no pro-regenerative clinical treatments in place to recover some of the functional capabilities of the damaged muscle. Free flap grafting, debridement of damaged tissue, and physical therapy are the only clinical standards available that offer little functional recovery benefits, even after years of consistent treatment. In this study, anti-inflammatory cytokine interleukin-10 in conjunction with autologous minced muscle was assessed as a possible treatment for VML injuries and its influences on cellular behavior within …

A Gis-Based Model To Assess On-Site Sewage Facility (Ossf) Contamination Risk To Local Water Resources, Alvaro Garcia

Theses and Dissertations

In a collaborative effort between Texas Water Resources Institute (TWRI), Cameron County Public Health (CCPH), Texas A&M AgriLife Extension (TAMAE), and the University of Texas Rio Grande Valley (UTRGV), a GIS database that includes relevant OSSF information, such as location, system age, lot size, and other important parameters was created.

This OSSF database, along with publicly available GIS data, was used to create an integrative GIS-based risk assessment model where OSSF risk parameters were assigned a risk factor and combined into a spatial contamination risk for surrounding areas and their receiving waterbodies. Parameters were broken down into two categories: environmental …

Synthesis And Characterization Of Centrifugally Spun Molybdenum-Based Nanomaterials For Lithium-Ion Batteries, Ramiro Gonzalez Jr.

Theses and Dissertations

The work presented in this thesis focuses on the processing and development of transition metal compound composite fibers as anode materials for rechargeable lithium-ion batteries (LIBs). Among the transition metal compounds, molybdenum compounds have risen as promising candidates of advanced electrode materials, in view of their natural abundance, virtuous mechanical/thermal stability, rich chemistry, high theoretical specific capacity, and multiple oxidation states of Mo. The current work reports synthesize MoO2/C and MoO3/C composite fibers drawn from centrifugal spun ammonium molybdate/PAN precursor fibers, followed by a thermal treatment stabilizing in air and calcination under argon atmosphere. The weight ratios of (MoOx, 2 …

Characteristics Analysis Of Electrochemical Impedance Spectroscopy (Eis) For Different Electrode Patterns, Shanzida Kabir

Theses and Dissertations

Electrochemical impedance spectroscopy (EIS) is a rapidly developing technique used in characterizing materials and interfaces. Using equivalent circuits as models can determine the electrical properties of heterogeneous systems like membranes or electrolytes. Different electrochemical processes like the electron transfer rate of a specific reaction or the capacitive behavior of the system, or even the diffusion-limited response can coincide. EIS is applicable to determine different electrochemical processes that can happen simultaneously. The purpose of this research is to find the optimal operating range for other AC electrokinetic mechanisms. Analysis of EIS can be helpful in both fundamental examinations of electrokinetic transport …

Integrated Processing Of Municipal Solid Waste For Maximizing Waste Reduction, Carbon Recovery And Fuel Production, Kameron J. King

Civil & Environmental Engineering Theses & Dissertations

Nationally and internationally, waste generation is increasing and along with it negative environmental impacts. Many people think waste ends at disposal; however, environmental impacts have already begun. Unfortunately, 50% of waste ends up in a landfill which is the third largest source of human related methane emissions and a leading cause of global climate change. This study investigated a novel waste management strategy in hopes of mitigating negative environmental effects caused by conventional waste management practices. The novelty of the study lies in the development of an integrated method of hydrothermal carbonization and an anaerobic digestion (HTC + AD) process …

Hydrothermal Processes For Extraction And Conversion Of Biomass To Produce Biofuels And Value-Added Products, Anuj Hemant Thakkar

Civil & Environmental Engineering Theses & Dissertations

An integrated biorefinery approach based on subcritical hydrothermal processes was developed to maximize utilization of biomass components by producing multiple products. Biomass from various sources like agricultural waste (lignocellulose), food waste (spent yeast), and dedicated cultivation (micro-algae) was used in this research.

Corn stover (agricultural waste) was hydrothermally pretreated to remove lignin and xylan while preserving most of the glucan. The pretreated corn stover was utilized to produce levulinic acid (thermochemically) and fermentable sugars (biochemically). The solid residue generated during levulinic acid production was utilized to produce biocarbon electrode material. The results generated from the experiments were used for designing …

Synthesis And Characterization Of 4,6-Protected Glucosamine Derivatives And Branched Glycoconjugates, Jonathan Bietsch

Chemistry & Biochemistry Theses & Dissertations

Low molecular weight gelators (LMWGs) are small molecules that self-assemble in appropriate solvents to form three dimensional networks that immobilize the solvent, creating a supramolecular gel. The self-assembly of LMWGs occurs through non-covalent interactions such as hydrogen bonding, aromatic interactions, donor-acceptor interactions, Van der Waals interactions, hydrophobic forces, halogen bonding, etc. Due to self-assembly occurring through reversible non-covalent interactions, supramolecular gels can undergo a gel to solution transformation. Because of this, these materials can be sensitive to external stimuli such as temperature changes, pH changes, and other stimuli that effect non-covalent interactions. This makes the synthesis of LMWG’s an appealing …

Effect Of Long And Short Chain Fatty Acids On Methane Yield And Microbial Community Composition In Anaerobic Co-Digestion, Emmaline Spier Camposano

All Theses

Fats, oils and greases are produced from a variety of industries, including animal rendering operations, vegetable oil processing plants and the hospitality industry. These hydrophobic, COD-rich compounds are known to cause issues in municipal wastewater collection and treatment systems. Anaerobic co-digestion has been shown to be an effective way to treat FOG and presents an opportunity to produce greater quantities of biogas. However, many microorganisms are sensitive to the degradation products of FOG, including long and short chain fatty acids. Two studies were performed to address potential inhibitory effects of both.

The first study co-digested various percentages of FOG with …