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Program And Proceedings: Nebraska Academy Of Sciences 1880–2022, 142nd Anniversary Year, One Hundred-Thirty-Second Annual Meeting, April 22, 2022

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Anthropology

Applied Science and Technology

Biological Sciences

Biomedical Sciences

Chemistry

Earth Sciences

Environmental Sciences

Physics

2022 Maiben Lecture: Dan Sitzman

2022 Friend of Science Award: Julie Sigmon and Chris Schaben

Feasibility Of The Lifting Full-Body Model To Simulate Squatting Tasks, Reese Moschetta, Yeageon Song, Bridget Gagnier, Barry Bait

21st Annual Celebration of Undergraduate Research and Creative Activity (2022)

Lower back pain is one of the most common injuries involving healthcare workers who perform manual patient-handling tasks. Currently, no freely available subject-specific model to explore internal joint loading during these tasks exists. A proof-of-concept study to simulate squatting tasks with the OpenSim Lifting Full-Body (LFB) Model is presented. Thirty-nine reflective markers were placed on bony landmarks of the upper and lower body of a 20-year old able-bodied female volunteer. Ten electromyography (EMG) sensors were placed bilaterally on the following muscles; lumbar erector spinae, thoracic erector spinae, rectus femoris, rectus abdominis, and the external obliques. Position (100 Hz), ground reaction …

A Review Of Avian-Inspired Morphing For Uav Flight Control, Christina Harvey, Lawren L. Gamble, Christian R. Bolander, Douglas F. Hunsaker, James J. Joo, Daniel J. Inman

Mechanical and Aerospace Engineering Faculty Publications

The impressive maneuverability demonstrated by birds has so far eluded comparably sized uncrewed aerial vehicles (UAVs). Modern studies have shown that birds’ ability to change the shape of their wings and tail in flight, known as morphing, allows birds to actively control their longitudinal and lateral flight characteristics. These advances in our understanding of avian flight paired with advances in UAV manufacturing capabilities and applications has, in part, led to a growing field of researchers studying and developing avian-inspired morphing aircraft. Because avian-inspired morphing bridges at least two distinct fields (biology and engineering), it becomes challenging to compare and contrast …

Alpha Synuclein: A Therapeutic Target And Biomarker For Parkinson’S Disease, Max Chase

USF Tampa Graduate Theses and Dissertations

Parkinson’s Disease is the second most common neurodegenerative disease after Alzheimer’s Disease, and the most common motor disorder. In fact, nearly a third of those with AD have PD. A major hallmark of PD is the appearance of Lewy Bodies, proteinaceous cytoplasm inclusions, that build up and spread throughout the CNS in a prion like fashion. The major component of these Lewy Bodies is a protein called alpha-synuclein. Alpha-syn is a 14kDa protein made of 140 amino acids and found in the presynaptic ends of CNS neurons, acting as a chaperone and regulator. The protein is also found in the …

Public School Nurse To Student Ratios: Does It Affect Absenteeism?, Laura Beth Hobbs

ATU Theses and Dissertations 2021 - Present

The demands for adequate nursing workloads in public schools have increased with special needs children in Arkansas. School nurses are a necessary component of student academic achievement and physical well-being. The purpose of this study is to examine the effects that nurse-to-student ratios have on absenteeism by providing a convenience sample questionnaire to Arkansas K-12 public school superintendents. The questionnaire has examined the relationship between school nurse ratios and school absentee numbers. A four-question survey was sent out to 233 Arkansas K-12 public schools using a QuestionPro survey. Superintendents were asked about their school district numbers for the 2020-2021 school …

Nanoparticulate Carriers For Drug Delivery, Samantha Lokelani Crossen, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Drug delivery with nanoparticulate carriers is a new and upcoming research area that is making major changes within the pharmaceutical industry. Nanoparticulate carriers are discussed, particularly, engineered nanoparticulate carriers used as drug delivery systems for targeted delivery. Nanoparticulate carriers that are used for drug delivery systems include polymers, micelles, dendrimers, liposomes, ceramics, metals, and various forms of biological materials. The properties of these nanoparticulate carriers are very advantageous for targeted drug delivery and result in efficient drug accumulation at the targeted area of interest, reduced drug toxicity, reduced systemic side effects, and more efficient use of the drug overall. Nanoparticlulate …

Bms 202: Human Anatomy And Physiology Laboratory Oer Curation, Chealsye Bowley

Curated OER Collections

This OER curation is an annotated bibliography of prospective OER for the GVSU course BMS 202: Human Anatomy and Physiology Laboratory, assembled by request from the instructor.

Bio-Ionic Liquid Functionalized Hydrogels Towards Smart Tissue Regeneration, Vaishali Krishnadoss

Theses and Dissertations

A blend of scaffolds, biologically active molecules, and cells are required to assemble functional constructs to repair and regenerate damaged tissue or organ via tissue engineering. The scaffold supports cell growth and proliferation and acts as a medium for diverse cellular activities. Even though hydrogel's high-water content and flexible nature make it a pronounced applicant as a scaffold, they exhibit significant technical limitations such as the absence of cell-binding motifs, lack of oxygen, conductivity, adhesive properties, growth of cells in a 3-dimensional (3D) microenvironment. In this thesis, a novel material platform is evaluated and studied to address the concerns mentioned …

Europium-Doped Cerium Oxide Nanoparticles For Microglial Aβ Clearance And Homeostasis, Jatin Machhi, Pravin Yeapuri, Milica Markovic, Milankumar Patel, Wenhui Yan, Yaman Lu, Jacob D. Cohen, Mahmudul Hasan, Mai Mohamed Abdelmoaty, You Zhou, Huangui Xiong, Xinglong Wang, R. Lee Mosley, Howard E. Gendelman, Bhavesh D. Kevadiya

Nebraska Center for Biotechnology: Faculty and Staff Publications

Alzheimer’s disease (AD) is the most common neurodegenerative disorder. Pathologically, it is characterized by the deposition of amyloid beta (Aβ) plaques and presence of neurofibrillary tangles. These drive microglia neuroinflammation and consequent neurodegeneration. While the means to affect Aβ plaque accumulation was achieved how it affects disease outcomes remains uncertain. Cerium oxide (CeO₂) reduces Aβ plaques, oxidative stress, inflammation, and Alzheimer’s disease (AD) signs and symptoms. Specifically, CeO₂ nanoparticles (CeO₂NPs) induces free radical scavenging and cell protective intracellular signaling. This can ameliorate the pathobiology of an AD-affected brain. In order to investigate, CeO₂NPs …

Assessing Augmented Reality Instruction In Manufacturing Engineering Education, Janine Draper Price

Theses and Dissertations

Augmented Reality (AR) is fast-growing technology that has proved itself in many applications, including manufacturing environments. Manufacturing engineers benefit in an industrial environment by harnessing this technology in the workplace to guide workers through a variety of tasks. It is no longer a question on whether it is useful, but what are the best ways of applying the technology. Currently there are no published studies on ways to use augmented reality in a Manufacturing Engineering Educational Environment (MEEE). This study examines various ways that AR can be used in an MEEE setting and assesses the value of such applications. This …

2022- The Twenty-Sixth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Twenty-sixth Annual Symposium of Student Scholars, held on April 19, 2022. Includes abstracts from the presentations and posters.

Antiviral Polymers: A Review, Ali Akbari, Ashkan Bigham, Vahid Rahimkhoei, Sina Sharifi, Esmaiel Jabbari

Faculty Publications

Polymers, due to their high molecular weight, tunable architecture, functionality, and buffering effect for endosomal escape, possess unique properties as a carrier or prophylactic agent in preventing pandemic outbreak of new viruses. Polymers are used as a carrier to reduce the minimum required dose, bioavailability, and therapeutic effectiveness of antiviral agents. Polymers are also used as multifunctional nanomaterials to, directly or indirectly, inhibit viral infections. Multifunctional polymers can interact directly with envelope glycoproteins on the viral surface to block fusion and entry of the virus in the host cell. Polymers can indirectly mobilize the immune system by activating macrophages and …

Microscopic Nuclei Classification, Segmentation, And Detection With Improved Deep Convolutional Neural Networks (Dcnn), Md Zahangir Alom, Vijayan K. Asari, Anil Parwani, Tarek M. Taha

Electrical and Computer Engineering Faculty Publications

Background Nuclei classification, segmentation, and detection from pathological images are challenging tasks due to cellular heterogeneity in the Whole Slide Images (WSI). Methods In this work, we propose advanced DCNN models for nuclei classification, segmentation, and detection tasks. The Densely Connected Neural Network (DCNN) and Densely Connected Recurrent Convolutional Network (DCRN) models are applied for the nuclei classification tasks. The Recurrent Residual U-Net (R2U-Net) and the R2UNet-based regression model named the University of Dayton Net (UD-Net) are applied for nuclei segmentation and detection tasks respectively. The experiments are conducted on publicly available datasets, including Routine Colon Cancer (RCC) classification and …

Optimizing The Self-Healing Efficiency Of Hydrogel Encapsulated Bacteria In Concrete, Ricardo Hungria

LSU Master's Theses

Calcium carbonate precipitation through microbial means is a promising pathway for concrete self-healing technologies, mainly for its microcrack sealing attributes. The main goal of this project was to study and optimize the crack healing efficiency of hydrogel encapsulated bacteria in concrete. To achieve this purpose, Bacillus pseudiformus was implemented as the bacteria strain at a concentration of 10⁸ cells/ml. This bacterium strain along with yeast extract was combined along with three different mineral precursors corresponding to magnesium acetate, calcium lactate, and sodium lactate. All these three precursors were evaluated at two concentrations (67.76 mM/l and 75 mM/l). For each …

Assembly Of Nanostructures At Solid-Liquid And Liquid-Air Interfaces, Yingzhen Ma

LSU Doctoral Dissertations

Molecular and nanoscale colloids such as surfactant, fatty acid and metallic nanoparticles are widely used in numerous applications such as detergents, biomedicine, and catalyst. The assemblies of these colloids show different morphological behavior in aqueous solution due to the wide range of intermolecular interactions such as hydrogen bonding, van der Waals, and electrostatics. The morphology of these assemblies can be changed by environmental factors including temperature, ionic strength, and salinity. However, the guidance to direct assembled state of colloidal assemblies at heterogenous interfaces under various external stimuli remains poorly understand. In this Ph.D. dissertation, we show the adsorption and reconfiguration …

Self-Supervised Joint Image Reconstruction And Coil Sensitivity Calibration In Parallel Mri Without Ground Truth, Yuyang Hu

McKelvey School of Engineering Graduate Student Theses & Dissertations

No abstract provided.

Fabrication Of Microfluidic Devices To Study Confined Collective Migration Of Breast Cancer Cells, Linh Luong

Symposium of Student Scholars

Cells in our body mostly exist in confined environments. They are surrounded by neighboring cells, tissues, and the extracellular matrix. The changes in these surrounding environments influence cell behaviors. Therefore, studying cell mechanics plays a significant role to understand how cancer cells migrate and what primary factors that control cancer metastasis. Many studies have been developed to study how cancer cells migrate in the body. However, these experiments in vivo are complicated and incredibly challenging. Another approach is to perform experiments in vitro instead. However, to obtain relevant results, a specific experimental apparatus must be designed to confine cells. Glass …

Design And Computational Validation Of A Shear Stress Bioreactor For Conditioning Vascular Tissue To Time-Varying Multidirectional Fluid Shear Stress, Rajeshwari Raja, Philippe Sucosky, Jason Shar

Symposium of Student Scholars

Design and Computational Validation of a Shear Stress Bioreactor for Conditioning Vascular Tissue to Time-Varying Multidirectional Fluid Shear Stress

Author: Rajeshwari Raja Mentor: Dr. Jason A. Shar Department of Mechanical Engineering Kennesaw State University 1100 South Marietta Pkwy SE, 30060

Altered biological environments and conditions, such as microgravity and pregnancy, can impact vascular blood flow and, in turn, generate fluid wall shear stress (WSS; frictional force generated on the tissue surface due to blood flow) abnormalities. These abnormalities are known to affect cardiovascular tissue biology and can be replicated experimentally using a cone-and-plate shear stress bioreactor. This device exposes tissue …

Determination Of The Heating Time Constant For Root Crops, Z K. Ergasheva, Beraat Ozcelik

Technical science and innovation

Convective drying refers to one of the energy-intensive processes used in chemical, woodworking, food and other industries. Therefore, in modern conditions, when there is a growing shortage and an increase in energy tariffs, it is important to develop and apply new effective methods of drying wet materials in industrial production, create high-performance drying equipment, improve the operation of existing dryers, which will contribute to the rational use of natural resources, reduce the cost of finished products and increase the competitiveness of production. Root crops are plants in which nutrients are concentrated in tubers or roots. Jerusalem artichoke refers to sugar-containing …

Onsite Water Reuse: Fate Of Indicator Bacteria, Antibiotic Resistant Genes, Environmental Impacts, And User Perceptions, Michelle B. Henderson

USF Tampa Graduate Theses and Dissertations

Changes in water use, climate, and urbanization have shifted how water resources are used and defined. Wastewater is increasingly regarded as a viable resource to address challenges in non-potable and potable water applications. When dealing with water reuse, water quality and quantity are of the utmost importance; and the final product must be suitable for its intended purpose and acceptable to users. The first portion of this research analyzed the performance and environmental impacts of pilot-scale Hybrid Adsorption Biological Treatment Systems (HABiTS) for onsite wastewater treatment and reuse. Various configurations were investigated to increase HABiTS performance and ability to produce …

Benchmark Of Clustering Techniques And Potential Applications To Polymer Material Science, Rachel Drake

Liberty University Research Week

Undergraduate

Applied

A Preliminary Comparative Study Of Molecular Visualization Software For Education, Ruoming Shen

Modeling, Simulation and Visualization Student Capstone Conference

Chemistry and biology are sciences vital for understanding metabolic processes, developing disease treatments, and improving environmental conditions. With extensive knowledge of biochemistry, we can take advantage of a material’s unique chemical composition and properties in various applications. Visualization software is essential for analyzing complex chemical and biological structures and predicting their interactions with each other. This paper presents a preliminary study of three open source molecular visualization software tools - Visual Molecular Dynamics (VMD), Jmol, and Mol*, and evaluates their strengths and deficiencies. This paper utilizes the March Molecule of the Month, Vascular Endothelial Growth Factor (VEGF), from the Protein …

Image Processing Algorithms For Detection Of Anomalies In Orthopedic Surgery Implants, Alexander William Wiese

Theses and Dissertations

Orthopedic implant procedures for hip implants are performed on 300,000 patients annually in the United States, with 22.3 million procedures worldwide. While most such operations are successfully performed to relieve pain and restore joint function for the duration of the patient's life, advances in medicine have enabled patients to outlive the life of their implant, increasing the likelihood of implant failure. There is significant advantage to the patient, the surgeon, and the medical community in early detection of implant failures.The research work presented in this thesis demonstrates a non-invasive digital image processing technique for the automated detection of specific arthroplasty …

Fumarate-Based Polymers: Oligo(Poly(Ethylene Glycol) Fumarate) And Poly(Butylene Fumarate) For Tissue Engineering Heart Valve And Bone Tissue, Christian T. Denny

Biomedical Engineering ETDs

Tissue engineering is an emerging field that came from the fields of medicine, materials science, and engineering. The foundation of tissue engineering uses a paradigm that incorporates cells, biomaterials, and exogenous factors to create living tissues for medical, pharmaceutical, and research purposes. Within the last 100 years, biomaterials have been developed to solve many medical and research problems. As biomaterials have developed throughout the years new materials have been developed to have specific properties appropriate for medical applications. Fumarate is a naturally derived molecule in the body and has been found useful for developing polyesters that can be crosslinked into …

Let's Get Serious About It: Plastic-Free Campus Initiative, Geoffrey Kain, Camdyn Doucette, Regan Bossie

Sustainability Conference

On February 23, 2022, the UN agreed to start negotiating a world-first global treaty on plastic waste--since nearly 200 nations unanimously agreed to move toward a legally binding plastics treaty by 2024. In 2019 the UN Environmental Programme report highlighted that "our world is drowning in plastic." As with the climate change crisis (to which plastics production and disposal are also linked), the data resoundingly illustrate the imminent systemic threat that disposable plastics pose to the world's seas, freshwater sources, soils, food supply, air, and species. Nevertheless, plastics production is predicted to rise dramatically over the next 20 years, with …

Modeling The Bombardier Beetle Fire Extinguisher: Verifying Computational Results, Elijah Yoder

Liberty University Research Week

Undergraduate

Applied

Limits Of Detection Of Mycotoxins By Laminar Flow Strips: A Review, Xinyi Zhao, Hugh Byrne, Christine M. O’Connor, James Curtin, Furong Tian

Articles

Mycotoxins are secondary metabolic products of fungi. They are poisonous, carcinogenic, and mutagenic in nature and pose a serious health threat to both humans and animals, causing severe illnesses and even death. Rapid, simple and low-cost methods of detection of mycotoxins are of immense importance and in great demand in the food and beverage industry, as well as in agriculture and environmental monitoring, and, for this purpose, lateral flow immunochromatographic strips (ICSTs) have been widely used in food safety and environmental monitoring. The literature to date describing the development of ICSTs for the detection of different types of mycotoxins using …

Practical Considerations And Applications For Autonomous Robot Swarms, Rory Alan Hector

LSU Doctoral Dissertations

In recent years, the study of autonomous entities such as unmanned vehicles has begun to revolutionize both military and civilian devices. One important research focus of autonomous entities has been coordination problems for autonomous robot swarms. Traditionally, robot models are used for algorithms that account for the minimum specifications needed to operate the swarm. However, these theoretical models also gloss over important practical details. Some of these details, such as time, have been considered before (as epochs of execution). In this dissertation, we examine these details in the context of several problems and introduce new performance measures to capture practical …

Machine Learning Based Medical Image Deepfake Detection: A Comparative Study, Siddharth Solaiyappan, Yuxin Wen

Engineering Faculty Articles and Research

Deep generative networks in recent years have reinforced the need for caution while consuming various modalities of digital information. One avenue of deepfake creation is aligned with injection and removal of tumors from medical scans. Failure to detect medical deepfakes can lead to large setbacks on hospital resources or even loss of life. This paper attempts to address the detection of such attacks with a structured case study. Specifically, we evaluate eight different machine learning algorithms, which include three conventional machine learning methods (Support Vector Machine, Random Forest, Decision Tree) and five deep learning models (DenseNet121, DenseNet201, ResNet50, ResNet101, VGG19) …

Theranostic Copolymers Neutralize Reactive Oxygen Species And Lipid Peroxidation Products For The Combined Treatment Of Traumatic Brain Injury, Aaron Priester, Richard Waters, Ashleigh Abbott, Krista Hilmas, Klaus Woelk, Hunter A. Miller, Aria W. Tarudji, Connor C. Gee, Brandon Mcdonald, Forrest M. Kievit, Anthony J. Convertine

Chemistry Faculty Research & Creative Works

Traumatic brain injury (TBI) results in the generation of reactive oxygen species (ROS) and lipid peroxidation product (LPOx), including acrolein and 4-hydroxynonenal (4HNE). The presence of these biochemical derangements results in neurodegeneration during the secondary phase of the injury. The ability to rapidly neutralize multiple species could significantly improve outcomes for TBI patients. However, the difficulty in creating therapies that target multiple biochemical derangements simultaneously has greatly limited therapeutic efficacy. Therefore, our goal was to design a material that could rapidly bind and neutralize both ROS and LPOx following TBI. To do this, a series of thiol-functionalized biocompatible copolymers based …