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Progress Report On The Effect Of Introducing Biological And Environmental Discipline-Themed Problems In Engineering Mechanics Statics On Students’ Self-Efficacy And Perceived Value Of The Course, Yemisi Oyewola Apr 2023

Progress Report On The Effect Of Introducing Biological And Environmental Discipline-Themed Problems In Engineering Mechanics Statics On Students’ Self-Efficacy And Perceived Value Of The Course, Yemisi Oyewola

Student Research Symposium

This study extends the previous research which examined the effect of introducing biological and environmental discipline-themed problems in Engineering Mechanics Statics on students’ Self-Efficacy (SE) and perceived value (PV) of the course. The previous research was carried out using pooled data from 133 participants over 3 semesters. Additional data from 126 participants were collected over the next two semesters making it a total of 262 participants. The result from the previous study showed a statistically significant increase in the perceived value of the students even though their self-efficacy did not significantly change. However, despite an increased sample size, the result …

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Optimizing Treatment Of Cytomegalovirus, Alisa Dabb Apr 2023

Optimizing Treatment Of Cytomegalovirus, Alisa Dabb

Student Research Symposium

The current treatment to Cytomegalovirus, ganciclovir, kills neutrophils, a type of cell in the immune system. In an effort to reduce the concentration of ganciclovir, quercetin and poloxamer 188 have been added in treatment in a cellular and mouse model. This treatment has been successful, but can be further optimized by reworking the ratio of quercetin to poloxamer 188 and by adding vitamin c to prevent oxidation.

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Deficit Irrigation Management For Irrigated Corn In Nebraska: Economically Viable?, Lia Nogueira, Cory Walters, Emily O'Donnell, E. Wesley F. Peterson, Suat Irmak Apr 2023

Deficit Irrigation Management For Irrigated Corn In Nebraska: Economically Viable?, Lia Nogueira, Cory Walters, Emily O'Donnell, E. Wesley F. Peterson, Suat Irmak

Cornhusker Economics

In this study we determine the economic value of deficit irrigation management using both technological and methodological advancements. The use of soil moisture probes represents the technological improvement. We provide improvements in the methodology as follows. Regarding data, we employ a field-size study, instead of plots, where the irrigation decision is determined by the moisture level in the soil measured through a soil moisture probe. Regarding the understanding of the yield response to water, although we examine the commonly used quadratic function, we improve upon this specification by also examining an alternative response function, the linear response stochastic plateau. Our …

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Quantifying And Managing Anthropogenic And Drought Influences On Instream Temperatures, Abbygael Johnson Apr 2023

Quantifying And Managing Anthropogenic And Drought Influences On Instream Temperatures, Abbygael Johnson

Student Research Symposium

The western US is currently experiencing effects of one of the worst droughts in 1200 years. These effects are evident in our rivers, as shown by broad scale reductions in baseflow. This lack of runoff combined with growing demands has resulted in the overallocation of the water contained within our rivers and reservoirs. Water temperature is the key factor in many biological, chemical, and physical processes, making it critical to the health of ecosystems . River temperatures are a function of many factors including weather and tree canopy, but also instream flow volumes and water residence time. When instream flows …

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Understanding The Role Of A Putative Type I Polyketide Synthase In Chlorflavonin Biosynthesis, Ammar Mussaji Apr 2023

Understanding The Role Of A Putative Type I Polyketide Synthase In Chlorflavonin Biosynthesis, Ammar Mussaji

Student Research Symposium

Flavonoids are an important class of plant secondary metabolites with a variety of biological functions in the development processes of hosts. These molecules have also shown health-benefiting properties such as antioxidant and anti-inflammatory activities. As such, they are commonly used as pharmaceuticals and nutraceuticals. In plants, flavonoids are assembled through a type III polyketide synthase (PKS) and associated tailoring enzymes such as hydroxylase and glycosyltransferase. Some filamentous fungi also produce flavonoids, such as chlorflavonin from Aspergillus candidus. Chlorflavonin is a novel halogenated flavonoid found in nature reported to possess antifungal and anti-tuberculosis activity. Unlike plants, the biosynthetic process of flavonoids …

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Glycosylation Of Anti-Tb Agent Chlorflavonin For Combating Mycobacterium Tuberculosis, Jie Ren Apr 2023

Glycosylation Of Anti-Tb Agent Chlorflavonin For Combating Mycobacterium Tuberculosis, Jie Ren

Student Research Symposium

More than two billion people were infected by the bacterial pathogen Mycobacterium tuberculosis (Mtb) in 2020. However, during the past 50 years, the first-line (isoniazid, delamanid, and rifampicin) and second-line (capreomycin, streptomycin, and cycloserine) therapies have remained unchanged with disadvantages such as long treatment periods and severe side effects. The slow development of anti-TB drugs cannot combat the fast development of drug resistant M. tuberculosis strains from multidrug-resistant (MDR) into extensively drug resistant (XDR), which further hinders the World Health Organization’s goal to end the global TB pandemic by the year 2035. Flavonoids are a type of natural product with …

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Does Diet Effect The Brain?, Janna Hart Apr 2023

Does Diet Effect The Brain?, Janna Hart

Student Research Symposium

Short-chain fatty acids are biomolecules produced from bacterial fermentation of dietary fiber in the gut. Short-chain fatty acids are used in the gut to supply energy and reduce inflammation but are also believed to have effects on the brain. While we do not know how short-chain fatty acids affect the brain and behavior, recent research has led to the idea of using dietary changes as a treatment for mental health disorders. In my research, we aimed to visualize where short-chain fatty acids act in the brain with a particular focus on neural immune cells called microglia and the neurons that …

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"Challenging The Known." 16th Annual Research Week: Event Proceedings, University Of The Incarnate Word Apr 2023

"Challenging The Known." 16th Annual Research Week: Event Proceedings, University Of The Incarnate Word

Excellence Summit (Research Week) Archived Proceedings

Presentations of completed and ongoing research activity conducted by graduate students, undergraduate students, and faculty at University of the Incarnate Word. Includes poster, podium, visual arts, interactive demo, and creative and performing arts presentations. Coordinated and presented by the Office of Research and Graduate Studies.

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One-Dimensional And Two-Dimensional Simulations Of Helical Homopolymers: A Comparative Analysis Of Energy Stabilization And Efficiency, Matthew Hooks, Nathan Roberts, Matthew Williams Ph. D. Apr 2023

One-Dimensional And Two-Dimensional Simulations Of Helical Homopolymers: A Comparative Analysis Of Energy Stabilization And Efficiency, Matthew Hooks, Nathan Roberts, Matthew Williams Ph. D.

Steeplechase: An ORCA Student Journal

The purpose of our work is to analyze the results of a two-dimensional parallel tempering simulation of a coarse-grained helical homopolymer. We aim to measure the efficiency of the simulation and apply this efficiency to the theoretical protein free energy landscape.The stable states for helical homopolymers will be analyzed using the folding funnel theory of free energy landscapes for given polymer configurations. The genesis of each simulation is defined by a randomly configured polymer; as time progresses, the energy of each structure decreases until equilibrium is reached. Data collected after equilibrium is reached is used to understand polymer behavior for …

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The Intersection Of Culturally Responsive Pedagogy And Engineering Design In Secondary Stem, Mariam Manuel, Jessica Gottlieb, Gina Svarovsky, Rebecca Hite Apr 2023

The Intersection Of Culturally Responsive Pedagogy And Engineering Design In Secondary Stem, Mariam Manuel, Jessica Gottlieb, Gina Svarovsky, Rebecca Hite

Journal of Pre-College Engineering Education Research (J-PEER)

The instructional practices of the engineering design process and culturally responsive pedagogy have each garnered national attention and multiple decades of research. Findings from the respective literature bases call for educators and policymakers to integrate these two pedagogical approaches into K-12 classroom instruction. Scholars have argued that this integration would improve student engagement and academic achievement. There is a significant amount of research that supports the positive student outcomes associated with each approach, yet there remains a dearth of literature that addresses the integration of these two practices into the science and mathematics content areas. The movement around educational reform …

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Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki Apr 2023

Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substituted 1,9-diazaphenothiazines show promising if not impressive in vitro anticancer potential, which is associated with the activation of the mitochondrial apoptosis pathway connected with to induction BAX, forming a channel in MOMP and releasing cytochrome c for the activation of caspases 9 and 3. In this publication, the lipophilicity of previously obtained 1,9-diazaphenothiazines was determined theoretically using various computer programs …

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Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki Apr 2023

Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substituted 1,9-diazaphenothiazines show promising if not impressive in vitro anticancer potential, which is associated with the activation of the mitochondrial apoptosis pathway connected with to induction BAX, forming a channel in MOMP and releasing cytochrome c for the activation of caspases 9 and 3. In this publication, the lipophilicity of previously obtained 1,9-diazaphenothiazines was determined theoretically using various computer programs …

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Fabrication Of Drug-Eluting Polycaprolactone And Chitosan Blend Microfibers For Topical Drug Delivery Applications, Mulugeta Gizaw, Diala Bani Mustafa, Shih-Feng Chou Apr 2023

Fabrication Of Drug-Eluting Polycaprolactone And Chitosan Blend Microfibers For Topical Drug Delivery Applications, Mulugeta Gizaw, Diala Bani Mustafa, Shih-Feng Chou

Mechanical Engineering Faculty Publications and Presentations

Chronic and non-healing wounds show delayed and incomplete healing process, which expose the patients to a high risk of infection. These types of wounds require frequent change of dressing, which is a burden on the patients. In addition, ideal dressing needs to meet the requirements in minimizing microbial infiltration and growth while balancing moisture and exchanging oxygen with outside environment. To overcome the challenge in frequent change of dressing and meet the design requirements, current researches have focused on the development of electrospun fibers with incorporation of small molecule drugs for sustained release purpose. In this study, electrospinning was performed …

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Mitochondrial Complex Iii Bypass Complex I To Induce Ros In Gpr17 Signaling Activation In Gbm, Sana Kari, Jeyalakshmi Kandhavelu, Akshaya Murugesan, Ramesh Thiyagarajan, Srivatsan Kidambi, Meenakshisundaram Kandhavelu Apr 2023

Mitochondrial Complex Iii Bypass Complex I To Induce Ros In Gpr17 Signaling Activation In Gbm, Sana Kari, Jeyalakshmi Kandhavelu, Akshaya Murugesan, Ramesh Thiyagarajan, Srivatsan Kidambi, Meenakshisundaram Kandhavelu

Department of Chemical and Biomolecular Engineering: Faculty Publications

Guanine nucleotide binding protein (G protein) coupled receptor 17 (GPR17) plays crucial role in Glioblastoma multiforme (GBM) cell signaling and is primarily associated with reactive oxidative species (ROS) production and cell death. However, the underlying mechanisms by which GPR17 regulates ROS level and mitochondrial electron transport chain (ETC) complexes are still unknown. Here, we investigate the novel link between the GPR17 receptor and ETC complex I and III in regulating level of intracellular ROS (ROSi) in GBM using pharmacological inhibitors and gene expression profiling. Incubation of 1321N1 GBM cells with ETC I inhibitor and GPR17 agonist decreased the ROS level, …

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Experimental And Computational Fluid Dynamics Investigation Of Mechanisms Of Enhanced Oil Recovery Via Nanoparticle-Surfactant Solutions, Nurudeen Yekeen, Ali Masoud Ali Elakkari, Javed Akbar Khan, Muhammad Ali, Ahmed Al-Yaseri, Hussein Hoteit Apr 2023

Experimental And Computational Fluid Dynamics Investigation Of Mechanisms Of Enhanced Oil Recovery Via Nanoparticle-Surfactant Solutions, Nurudeen Yekeen, Ali Masoud Ali Elakkari, Javed Akbar Khan, Muhammad Ali, Ahmed Al-Yaseri, Hussein Hoteit

Research outputs 2022 to 2026

The enhancement in surfactant performance at downhole conditions in the presence of nanomaterials has fascinated researchers’ interest regarding the applications of nanoparticle-surfactant (NPS) fluids as novel enhanced oil recovery (EOR) techniques. However, the governing EOR mechanisms of hydrocarbon recovery using NPS solutions are not yet explicit. Pore-scale visualization experiments clarify the dominant EOR mechanisms of fluid displacement and trapped/residual oil mobilization using NPS solutions. In this study, the influence of multiwalled carbon nanotubes (MWCNTs), silicon dioxide (SiO2), and aluminum oxide (Al2O3) nanoparticles on the EOR properties of a conventional surfactant (sodium dodecyl benzene sulfonate, …

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Design And Synthesis Of Plasmonic Nanoparticles For Nir Bioimaging: Investigating The Role Of Absorption And Scattering, Luis Dias Bumba Manuel Apr 2023

Design And Synthesis Of Plasmonic Nanoparticles For Nir Bioimaging: Investigating The Role Of Absorption And Scattering, Luis Dias Bumba Manuel

LSU Doctoral Dissertations

Nanoparticles have made vast advances in the realm of nanomedicine and bioimaging, enabling technologies such as photothermal therapy of malignant tumors and noninvasive monitoring of living tissue. Many of these innovations have only arisen in the last few decades with potential for growth in many avenues. The research shown in this work addresses some of the existing literature's void. Particularly solving synthesis challenges that have existed for more than 20 years in synthesizing Au nanoshells and establishing the potential for molecular-level deep imaging of plants. A novel investigation of the role of light absorption and scattering in bioimaging led to …

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Engineered Production Of Bioactive Polyphenolic O-Glycosides, Jie Ren, Caleb Don Barton, Jixun Zhan Apr 2023

Engineered Production Of Bioactive Polyphenolic O-Glycosides, Jie Ren, Caleb Don Barton, Jixun Zhan

Biological Engineering Faculty Publications

Polyphenolic compounds (such as quercetin and resveratrol) possess potential medicinal values due to their various bioactivities, but poor water solubility hinders their health benefits to humankind. Glycosylation is a well-known post-modification method to biosynthesize natural product glycosides with improved hydrophilicity. Glycosylation has profound effects on decreasing toxicity, increasing bioavailability and stability, together with changing bioactivity of polyphenolic compounds. Therefore, polyphenolic glycosides can be used as food additives, therapeutics, and nutraceuticals. Engineered biosynthesis provides an environmentally friendly and cost-effective approach to generate polyphenolic glycosides through the use of various glycosyltransferases (GTs) and sugar biosynthetic enzymes. GTs transfer the sugar moieties from …

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A Review On The Application Of 3d Printing Technology In Pavement Maintenance, Fangyuan Gong, Xuejiao Cheng, Qinghua Wang, Yi Chen, Zhanping You, Yu Liu Apr 2023

A Review On The Application Of 3d Printing Technology In Pavement Maintenance, Fangyuan Gong, Xuejiao Cheng, Qinghua Wang, Yi Chen, Zhanping You, Yu Liu

Michigan Tech Publications, Part 1

To examine the application and significance of 3D printing technology in pavement maintenance engineering, a review of the current developments in principles, types, materials, and equipment for 3D printing was conducted. A comparison and analysis of traditional methods and 3D printing for asphalt pavement maintenance led to an investigation of 3D asphalt printing technologies and equipment. As a result, the following suggestions and conclusions are proposed: 3D printing technology can increase the level of automation and standardization of pavement maintenance engineering, leading to effective improvements in worker safety, climate adaptability, repair accuracy, etc. For on-site repair of cracks and minor …

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Assessing The Ability Of Arduino-Based Sensor Systems To Monitor Changes In Water Quality, Josiah Hacker Apr 2023

Assessing The Ability Of Arduino-Based Sensor Systems To Monitor Changes In Water Quality, Josiah Hacker

Honors College Theses

Access to safe water is vital to public health. While developed countries like the United States are recognized as having reliable and safe water, many small water utilities struggle with supplying consistent water quality. Technicians of these utilities will periodically test water samples from the influent and throughout the distribution system. However, this laborious and costly process does not capture sudden changes in influent water quality due to environmental conditions or pipes breaking in the distribution system. Here I show how an Arduino-based sensor can be used as a real-time, low-cost monitor of water quality parameters. Specifically, I developed a …

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Overview Of The Application Of Remote Sensing In Effective Monitoring Of Water Quality Parameters, Godson Ebenezer Adjovu, Haroon Stephen, David James, Sajjad Ahmad Apr 2023

Overview Of The Application Of Remote Sensing In Effective Monitoring Of Water Quality Parameters, Godson Ebenezer Adjovu, Haroon Stephen, David James, Sajjad Ahmad

Civil and Environmental Engineering and Construction Faculty Research

This study provides an overview of the techniques, shortcomings, and strengths of remote sensing (RS) applications in the effective retrieval and monitoring of water quality parameters (WQPs) such as chlorophyll-a concentration, turbidity, total suspended solids, colored dissolved organic matter, total dissolved solids among others. To be effectively retrieved by RS, these WQPs are categorized as optically active or inactive based on their influence on the optical characteristics measured by RS sensors. RS applications offer the opportunity for decisionmakers to quantify and monitor WQPs on a spatiotemporal scale effectively. The use of RS for water quality monitoring has been explored in …

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Persistence Of Dna From Biocontained Genetically Engineered Microbes, Wentao Dai Apr 2023

Persistence Of Dna From Biocontained Genetically Engineered Microbes, Wentao Dai

McKelvey School of Engineering Graduate Student Theses & Dissertations

The utilization of genetically engineered microbes in environmental systems requires effective biocontainment mechanisms to ensure their safe operation. CRISPR-based kill switches are a promising solution, inducing cell death through site-specific DNA cleavage under specific environmental conditions. In this study, we aimed to assess the impact of CRISPR-based kill switches on the abundance and persistence of bacterial DNA. Our results revealed that while CRISPR-based kill switches were capable of achieving high reductions in viable Escherichia coli Nissle 1917 (EcN); the DNA largely remained intact. This was observed in two strains of EcN: one enabled with multi-locus genome cleavage, and the other …

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Hydrogen Bonding Versus Halogen Bonding: Spectroscopic Investigation Of Gas-Phase Complexes Involving Bromide And Chloromethanes, Hayden T. Robinson, Christian T. Haakansson, Timothy R. Corkish, Peter D. Watson, Allan J. Mckinley, Duncan A. Wild Apr 2023

Hydrogen Bonding Versus Halogen Bonding: Spectroscopic Investigation Of Gas-Phase Complexes Involving Bromide And Chloromethanes, Hayden T. Robinson, Christian T. Haakansson, Timothy R. Corkish, Peter D. Watson, Allan J. Mckinley, Duncan A. Wild

Research outputs 2022 to 2026

Hydrogen bonding and halogen bonding are important non-covalent interactions that are known to occur in large molecular systems, such as in proteins and crystal structures. Although these interactions are important on a large scale, studying hydrogen and halogen bonding in small, gas-phase chemical species allows for the binding strengths to be determined and compared at a fundamental level. In this study, anion photoelectron spectra are presented for the gas-phase complexes involving bromide and the four chloromethanes, CH3Cl, CH2Cl2, CHCl3, and CCl4. The stabilisation energy and electron binding energy associated with each complex are determined experimentally, and the spectra are rationalised …

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Enhancing Telomerase Activity In Saccharomyces Cerevisiae Through A Genetic Screen For Gain-Of-Function Mutations, Keenan Conley, Hailey Rietz, Mackenzie Neal, Melissa Mefford Apr 2023

Enhancing Telomerase Activity In Saccharomyces Cerevisiae Through A Genetic Screen For Gain-Of-Function Mutations, Keenan Conley, Hailey Rietz, Mackenzie Neal, Melissa Mefford

2023 Celebration of Student Scholarship - Poster Presentations

Telomeres are located at the ends of eukaryotic linear chromosomes and are composed of repeated nucleotide sequences. The main function of telomeres is to protect chromosomal ends. However, telomeres cannot be copied entirely during DNA replication leading to a gradual shortening known as the “end-replication problem”. To counteract this problem, the RNA-dependent enzyme complex telomerase works to extend telomeres and maintain the chromosomal ends which helps to prevent senescence. Understanding the structure and function of telomerase could have important implications for the development of anti-cancer therapeutics, since telomerase is over-active in >85% of all human cancers. While the general role …

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The Diversity Of Life By E.O. Wilson, Emma Collins, Matthew Grace, Brady Lawson, Michelle Lopez, Zane Rousey, Douglas Mock Apr 2023

The Diversity Of Life By E.O. Wilson, Emma Collins, Matthew Grace, Brady Lawson, Michelle Lopez, Zane Rousey, Douglas Mock

2023 Celebration of Student Scholarship - Poster Presentations

In The Diversity of Life, E. O. Wilson tells a tale about how our earth is on track for another extinction event and humans are at fault. Wilson discusses various topics such as environmental preservation, biodiversity and its importance, and how life has evolved over time. Wilson views biodiversity differently than many as he focuses on all species found in the ecosystem rather than narrowing his focus on one. He mentions how new species can be created by groups evolving and developing new skills or existing in new environments. Species are going extinct and being created constantly; these extinctions don't …

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Age And Growth Of The Highland Shiner (Notropis Micropteryx) In Rockcastle County, Kentucky, Caitlyn Senters, Zoe Baker, Shelbie Black, Jared Vise, David J. Eisenhour Apr 2023

Age And Growth Of The Highland Shiner (Notropis Micropteryx) In Rockcastle County, Kentucky, Caitlyn Senters, Zoe Baker, Shelbie Black, Jared Vise, David J. Eisenhour

2023 Celebration of Student Scholarship - Poster Presentations

Notropis micropteryx, the Highland Shiner, is common in small to large streams of the Cumberland, Tennessee, and upper Green River drainages. It usually inhabits rocky riffles (Eisenhour and Eisenhour 2004)). While their population size was assessed as stable by the IUCN in 2012, little is known about the age and growth of this minnow species. Despite being a small fish, attention must be given to the health of its population as it serves an ecological niche and impact on the surrounding ecosystem.

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Age And Growth Of The Popeye Shiner (Notropis Ariommus) In The Rockcastle River, Shelbie Black, Jared Vise, Zoe Baker, Caitlyn Senters, David J. Eisenhour Apr 2023

Age And Growth Of The Popeye Shiner (Notropis Ariommus) In The Rockcastle River, Shelbie Black, Jared Vise, Zoe Baker, Caitlyn Senters, David J. Eisenhour

2023 Celebration of Student Scholarship - Poster Presentations

The Popeye Shiner (Notropis ariommus), occupies clear, gravel runs and flowing pools of creeks and small rivers throughout the Ohio River basin, but has declined in many areas. This species is a small silvery minnow with an unusually large eye. Despite being a candidate for the endangered species list (Department of the Interior, 2011), little life-history data have been published, which are needed to make conservation management decisions.

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The Thrombin Cleavage Of Protein Tags Of Co-Repressors Umudab And Ddrr Of The Pathogen Acinetobacter Baumaniihave Been Optimized For Cross-Linkage, Mercy Hailu, Deborah Cook, Janelle Hare Apr 2023

The Thrombin Cleavage Of Protein Tags Of Co-Repressors Umudab And Ddrr Of The Pathogen Acinetobacter Baumaniihave Been Optimized For Cross-Linkage, Mercy Hailu, Deborah Cook, Janelle Hare

2023 Celebration of Student Scholarship - Poster Presentations

The Acinetobacter baumannii strain 17978 is a Gram-negative and nosocomial ESKAPE pathogen which utilizes its unique SOS genes, umuDAb and ddrR, to inhibit cell division and control mutagenesis in response to DNA damage.

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Challenges In Creating Circularized Versions Of Linear Chromosomes, Tanner Hamilton, Melissa A. Mefford Apr 2023

Challenges In Creating Circularized Versions Of Linear Chromosomes, Tanner Hamilton, Melissa A. Mefford

2023 Celebration of Student Scholarship - Poster Presentations

Prokayotic and eukarotic chromosome structure differs. Generally prokaryotes have a single circular chromosome, while eukaryotes have multiple linear chromosomes. Linear chromosomes contain telomeres, composed of repeated DNA sequences, at the ends of the chromosome. While telomeres play crucial roles in capping telomeres, they create an end-replication problem. To overcome this issue, most eukaryotes possess the ribonucleoprotein enzyme complex telomerase. Despite the existence of telomerase, telomeres nonetheless shorten with aging and are thought to be a major contributor to this phenomenon. On the other hand, telomerase is upregulated in >85% of human cancers in order to allow the uncontrolled cell proliferation …

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A Green Chemistry Experiment: Magnetic Citrate Alginate Hydrogels Remove Methylene Blue From Water, Katelynn R. Setters, Elizabeth M. Thomas Apr 2023

A Green Chemistry Experiment: Magnetic Citrate Alginate Hydrogels Remove Methylene Blue From Water, Katelynn R. Setters, Elizabeth M. Thomas

2023 Celebration of Student Scholarship - Poster Presentations

The objective of this research was to design a green chemistry experiment that synthesizes magnetic citrate alginate hydrogels and test their effectiveness for the removal of methylene blue (MB) dye. Methylene blue dye is a common water pollutant that is toxic, carcinogenic, and nonbiodegradable; thus, can cause a severe threat to human health and environmental safety. Hence, there is a need to develop an environmentally friendly, efficient technology for removing MB from wastewater.

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Comparison Of Methanol, Water, And Hplc Mobile Phase As The Solvent For Quantification Of Nicotine Using Hplc Method, Josie Traver, Emmalou Schmittzehe Apr 2023

Comparison Of Methanol, Water, And Hplc Mobile Phase As The Solvent For Quantification Of Nicotine Using Hplc Method, Josie Traver, Emmalou Schmittzehe

2023 Celebration of Student Scholarship - Poster Presentations

Nicotine is a highly addictive chemical present in the tobacco plant. E-cigarettes, predominantly used among the adolescent population, are becoming increasingly popular. We can quantify the nicotine levels in unknown solutions using HPLC (high-performance liquid chromatography) by first preparing a calibration curve from standard nicotine samples. This experiment aims to understand the difference between using various solvents for the nicotine samples and how using one solvent may be more effective.

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