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The Effect Of Maternal Diet On Fetal Development, Catherine Wilcox

Renée Crown University Honors Thesis Projects - All

Using mice as a model system, this study aimed to compare the effect of a high fat diet (HFD), high sugar diet (HSD) and a control diet (CD) on fetal growth and development at the time of birth (post-natal day 0 or PND 0), post-natal day 7 (PND 7) and post-natal day 14 (PND 14). Published literature has documented the effects of a negative in-utero environment on fetal development, but currently there is limited research regarding the continued effects on development after birth. Mouse pups were harvested and then imaged in 3-D using a high-resolution micro-computed tomography (micro-CT) system. Total …

Impulse, Dana Hess, Kyle Johnson, Eric Landwehr, Cindy Rickeman

Impulse (Jerome J. Lohr College of Engineering Publication)

College:
[Page] 2 Dealing with budget cuts: Dean Lewis Brown explains why the College needed to cut programs and people.
[Page] 6 Father, daughter, and Uncle Sam: Associate Dean Richard Reid and senior math student Lindsey Reid share the same address, but their experiences in Iraq were as different as 2003 and 2010.
[Page] 8 The choice of more top scholars: More of state’s top students are applying here. In 2009, scholarships were offered to forty students with thirty or better ACT scores; thirty-four of them accepted the offer.
[Page] 10 Rising female enrollment: Female enrollment at the College has …

Review Of Gasoline, Diesel, And Ethanol Biofuels From Grasses And Plants. By Ram B. Gupta And Ayhan Demirbas., Adam Liska

Great Plains Research: A Journal of Natural and Social Sciences (through 2013)

A new book on the production of biofuels by Gupta and Demirbas provides technical insight into the conversion processes that could provide a range of domestic fuels from plant materials to substitute for foreign oil. It focuses primarily on conversion processes for production of cellulosic ethanol, Fischer-Tropsch diesel, pyrolysis bio-oil, and hydrothermal biocrude from biomass resources, as well as "first-generation" grain ethanol and biodiesel from vegetable oil. In addition to a detailed summary of these chemical processes, the book provides a briefer treatment of related matters such as biofuel policy, economics, and environmental issues. The book does discuss the limitations …

Do Invasive Riparian Woody Plants Affect Hydrology And Ecosystem Processes?, Julie Huddle, Tala Awada, Derrel Martin, Xinhua Zhou, Sue Ellen Pegg, Scott Josiah

Great Plains Research: A Journal of Natural and Social Sciences (through 2013)

© 2011 Copyright by the Center for Greot Plains Studies, University of Nebraska-Lincoln

The Solvent Effectiveness On Extraction Process Of Seaweed Pigment, Warkoyo Warkoyo, Elfi Anis Saati

Makara Journal of Technology

Eucheuma cottonii seaweed is a species of seaweed cultured in Indonesian waters, because its cultivation is relatively easy and inexpensive. It has a wide variety of colors from green to yellow green, gray, red and brown, indicating photosynthetic pigments, such as chlorophyll and carotenoids. An important factor in the effectiveness of pigment extraction is the choice of solvent. The correct type of solvent in the extraction method of specific natural materials is important so that a pigment with optimum quality that is also benefical to the society can be produced. The target of this research is to obtain a high …

Hemocompatibility Of Silicon-Based Substrates For Biomedical Implant Applications, Lingyan Liu

Chemical, Biomolecular, and Corrosion Engineering Faculty Research

Silicon membranes with highly uniform nanopore sizes fabricated using microelectromechanical systems (MEMS) technology allow for the development of miniaturized implants such as those needed for renal replacement therapies. However, the blood compatibility of silicon has thus far been an unresolved issue in the use of these substrates in implantable biomedical devices. We report the results of hemocompatibility studies using bare silicon, polysilicon, and modified silicon substrates. The surface modifications tested have been shown to reduce protein and/or platelet adhesion, thus potentially improving biocompatibility of silicon. Hemocompatibility was evaluated under four categories—coagulation (thrombin–antithrombin complex, TAT generation), complement activation (complement protein, C3a …

Polygonal Spatial Clustering, Deepti Joshi

School of Computing: Dissertations, Theses, and Student Research

Clustering, the process of grouping together similar objects, is a fundamental task in data mining to help perform knowledge discovery in large datasets.  With the growing number of sensor networks, geospatial satellites, global positioning devices, and human networks tremendous amounts of spatio-temporal data that measure the state of the planet Earth are being collected every day.  This large amount of spatio-temporal data has increased the need for efficient spatial data mining techniques.  Furthermore, most of the anthropogenic objects in space are represented using polygons, for example – counties, census tracts, and watersheds.  Therefore, it is important to develop data mining …

Ultrasonic And Stereo-Optical Characterization Techniques For Applications In Mechanical Testing, Jonathan M. Hein

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

This thesis considers methods developed based on ultrasonic reflections from interfaces and stereo-optical surface strain measurements to study the mechanical characterization of materials and bodies. The ultrasonic method is used to characterize wave speed and attenuation for highly attenuating samples. The stereo-optical strain measurements are used to characterize the effects of genes on mechanical properties of bone, and the dynamic characterization of blast waves in the UNL Shock Wave Trauma Mechanics facility.

A method is described and developed for characterizing the wave speed and attenuation spectrums from reflected waves from the contact surface with an unknown material. The method is …

Section Abstracts: Astronomy, Mathematics And Physics With Materials Science

Virginia Journal of Science

Abstracts for the Astronomy, Mathematics, and Physics with Materials Science Section for the 89th Annual Meeting of the Virginia Academy of Science, May 25-27, 2011, University of Richmond, Richmond VA.

Role Of The 3'Lghrr In Tcdd-Induced Suppression Of The Immunoglobulin Heavy Chain, Jayharsh L. Panchal, Eric J. Romer, David Ellis, Tharu Fernando, Courtney E. W. Sulentic

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits antibody secretion and immunoglobulin heavy chain (IgH) expression. Our previous work has shown that a possible mechanism for inhibition of IgH expression could be inhibition of the 3’IgH regulatory region (3’IgHRR). The 3’IgHRR has four enhancer regions (hs3a; hs1,2; hs3b; hs4) which are purported to control IgH gene expression. Previously we demonstrated a sensitive inhibition by TCDD of LPS-induced 3’IgHRR activity which is correlated with an inhibition of LPS-induced hs1,2 enhancer activity; however, the hs4 enhancer showed TCDD-induced activation following the co-treatment of TCDD and LPS. Therefore, the objective of the current study was to determine if …

Micromachined Differential Scanning Calorimeter For Cellular Differentiation And Metabolism Monitoring, Robert Blise

Master's Theses (2009 -)

This thesis presents a micromachined differential scanning calorimeter (DSC) for cellular differentiation and metabolism monitoring. The misregulation of cell physiology due to disease increases the metabolic rate of the cell and therefore its heat output. Observing or monitoring the cell's heat output will lead to a method to detect diseased cells and distinguish them from normal cells.

The calorimetric chambers of the DSC were fabricated on a silicon nitride thin film, which allows for rapid thermal equilibrium and insulation. The temperature sensing element was a resistive temperature detector fabricated from nickel. The DSC incorporated integrated nickel resistive heaters to apply …

Evaluation Of A Novel Non-Penetrating Electrode For Use In Dna Vaccination, Amy Donate, Domenico Coppola, Yolmari Cruz, Richard Heller

Bioelectrics Publications

Current progress in the development of vaccines has decreased the incidence of fatal and non-fatal infections and increased longevity. However, new technologies need to be developed to combat an emerging generation of infectious diseases. DNA vaccination has been demonstrated to have great potential for use with a wide variety of diseases. Alone, this technology does not generate a significant immune response for vaccination, but combined with delivery by electroporation (EP), can enhance plasmid expression and immunity. Most EP systems, while effective, can be invasive and painful making them less desirable for use in vaccination. Our lab recently developed a non-invasive …

Numerical Prediction Of The Haemodynamic Impact Of Coronary Stent Implantation, Jonathan Murphy

Doctoral

Arterial restenosis limits the effectiveness of coronary stenting. Restenosis is caused by excessive tissue growth which is stimulated by arterial injury and alterations to the arterial WSS. The altered WSS results from stent-induced disturbances to the natural haelnodynamics of the artery. Recent numerical studies have predcted only minor digerences in altered WSS between different stent designs using a commonly employed threshold assessment technique. While it is possible that there are only minor differences, it is more likely that the assessment technique is incapable of fully elucidating the altered WSS created by stent implantation. This thesis proposes a methodology that involves …

Theoretical Analysis Of Laterally Vibrating Microcantilever Sensors In A Viscous Liquid Medium, Russell Cox

Dissertations (1934 -)

Dynamically driven microcantilevers are normally excited into resonance in the out-of-plane flexural mode. The beam's resonant frequency and quality factor are used to characterize the devices. The devices are well suited for operation in air, but are limited in viscous liquid media due to the increased viscous damping. In order to improve these characteristics, other vibration modes such as the in-plane (or lateral) flexural mode are investigated. In this work, microcantilevers vibrating in the in-plane flexural mode (or lateral direction) in a viscous liquid medium are investigated. The hydrodynamic forces on the microcantilever as a function of both Reynolds number …

Intraseasonal Management Strategies For Deficit Irrigation, Isaac I. N. Mortensen

Department of Agricultural Economics: Dissertations, Theses, and Student Research

Reduced availability of irrigation water to producers has led to the need for intraseasonal management strategies that efficiently use the limited supply of irrigation water.  Historical weather data was used to develop a range of conditions experienced at the location.  Sound weather data improves the dependability of management strategies.  Data from weather stations on the Automated Weather Data Network and the Colorado AgMet network were evaluated based upon net radiation and dew point temperature observations expected in an irrigated agricultural setting.  This weather data was used to create a relationship between the Penman-Montieth evapotranspiration (ET) and Hargreaves ET and …

Fitting Model Parameters To Patient Data Automatically Through Evolutionary Computation, Michael Wesley Sagan

Master's Theses (2009 -)

The Orthopaedic and Rehabilitation Engineering Center (O.R.E.C) has been studying two conditions which can wreak havoc on the human body's balance control system. The conditions being studied are cerebral palsy (CP) and adolescent idiopathic scoliosis (AIS)[1, 2, 3, 4, 5, 6]. A greater understanding of postural deficits in children with these conditions and the causes for these conditions may help researchers achieve better interventions and treatments [3]. A tool used to characterize postural stability is a bi-planar postural stability model. This model is designed where 10 parameter values have to be adjusted until the simulated data is statistically the same …

Experimental Investigation Of Natural Fiber Reinforced Composite, Irene Samy Fahim

Theses and Dissertations

There is a growing use of polymers in different applications worldwide. This phenomenon resulted in an enormous increase in the amount of plastic waste. These wastes have significant impacts on the environment including pollution and depletion of resources. Recycling plastic waste and reusing it helps in alleviating environmental degradation. The amount of recycled plastics all over the world not utilized is huge. U.S.A recycled 5.7% of the total plastics generated and Western Europe recycled 39% of total amount of plastics consumed [1]. This research studies the potential usage of virgin and recycled polymer reinforced with natural fiber such as rice …

Cradle To Gate Simple Life Cycle Assessment Of Biodiesel Production In Indonesi, Akhmad Hidayatno, Teuku Yuri M. Zagloel, Widodo Wahyu Purwanto, Carissa Carissa, Lindi Anggraini

Makara Journal of Technology

The focus of this research is to analyze potential environmental impact in the supply chain of palm oil biodiesel industries. Simple Life Cycle Assessment (LCA) is applied to analyze impacts, produced by the three main units in the supply chain of Palm-Oil-based Biodiesel, which are Palm Plantation, CPO mill, and Biodiesel Plant. We developed LCA calculation model using spreadsheet software, used to assess a number of input scenarios to evaluate the best scenario, in variation of: land quality, land area and the rate of clearing, land clearing technique and type of the original land. The biggest potential environmental impact is …

Blended Biogeography-Based Optimization For Constrained Optimization, Haiping Ma, Daniel J. Simon

Electrical and Computer Engineering Faculty Publications

Biogeography-based optimization (BBO) is a new evolutionary optimization method that is based on the science of biogeography. We propose two extensions to BBO. First, we propose a blended migration operator. Benchmark results show that blended BBO outperforms standard BBO. Second, we employ blended BBO to solve constrained optimization problems. Constraints are handled by modifying the BBO immigration and emigration procedures. The approach that we use does not require any additional tuning parameters beyond those that are required for unconstrained problems. The constrained blended BBO algorithm is compared with solutions based on a stud genetic algorithm (SGA) and standard particle swarm …

Light Sensor Platform Based On The Integration Of Bacteriorhodopsin With A Single Electron Transistor, Karl A. Walczak, Paul L. Bergstrom, Craig Richard Freidrich

Department of Electrical and Computer Engineering Publications

This paper reports on the integration of an optical protein with single electron transistors to form a nano-bio-hybrid device for sensing. Bacteriorhodopsin (bR) is an optoelectric protein that translocates a proton across a distance of several nanometers in response to an absorbed photon of incident light. This charge gradient results in a measurable voltage in the dried state. Single electron transistors (SETs) have active regions consisting of one or more quantum islands with a size typically 10 nanometers or less. Integrating bacteriorhodopsin with the gate of a SET provides a device capable of a modulated electrical output in response to …

Computational Genomic Signatures And Metagenomics, Ozkan U. Nalbantoglu

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Mathematical characterizations of biological sequences form one of the main elements of bioinformatics. In this work, a class of DNA sequence characterization, namely computational genomics signatures, which capture global features of these sequences is used to address emerging computational biology challenges. Because of the species specificity and pervasiveness of genome signatures, it is possible to use these signatures to characterize and identify a genome or a taxonomic unit using a short genome fragment from that source. However, the identification accuracy is generally poor when the sequence model and the sequence distance measure are not selected carefully. We show that the …

Addressing Water Quality Issues In Rural Cameroon With Household Biosand Filters, Laine Klopfensten, Laura Petrasky, Valerie Winton, Jeff Brown

Publications

This paper describes an ongoing collaboration between the Hope College student chapter of Engineers Without Borders – USA and the rural community of Nkuv in the Northwest Province of Cameroon related to improving drinking water quality using Manz biosand filters. The collaboration began in 2006 and focused on developing a community-based construction and distribution model for household water treatment units. Results from microbiology testing of the constructed filters indicate that this water treatment method is effective for improving water quality in rural areas. The results also highlight the need for ongoing assessment and adapting community education programs to provide necessary …

Electromagnetic And Heat Transfer Modeling Of Microwave Heating In Domestic Ovens, Krishnamoorthy Pitchai

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Microwave (MW) ovens are used extensively for heating a variety of not-ready-to-eat food products. It is vital to achieve target temperature uniformly throughout the food to inactivate foodborne pathogens to assure safety. Non-uniform heating of foods in microwave ovens is the major concern in assuring microbiological safety of such products. The non-uniform heating of foods in domestic microwave ovens is due to complex interactions of microwaves with foods. A comprehensive coupled electromagnetic and heat transfer model was developed using finite-difference time-domain based numerical method to understand the complex interaction of microwaves with foods. Simulation parameters such as cell size, heating …

Ionic Current Rectification Phenomena In Asymmetrical Polymer Nanopores Under Salt Gradients, Murat Bakirci

Mechanical & Aerospace Engineering Theses & Dissertations

The magnitude of current through a conical nanopore filled with an electrolyte solution depends on the polarity of the applied bias, indicating an asymmetric diode-like current-voltage (I-V) curve. This kind of phenomenon refers to ionic current rectification (ICR), which is of interest because many ion-channel proteins in cellular membranes are rectifying. In addition, ICR in nanopores can be used to control ion concentrations in nano- and microfluidic systems. In this study, the ICR phenomenon through a conical nanopore simultaneously subjected to an electric field and salt concentration gradient is experimentally and numerically investigated.

The experiments were conducted in an Izon's …

Long Term Surface Power Generator Design For Mars: Autonomously Deployable Photovoltaic Solar Arrays Along With Regenerative Fuel Cell Modules, Omer Demirok

Mechanical & Aerospace Engineering Theses & Dissertations

This thesis studies the feasibility of incorporating a large autonomously deployed photovoltaic solar array power system as the primary power source for a large fixed Mars base. A mission duration of 10 Earth years has been assumed and the nominal power demands have been specified as a minimum of 40 kW, during daytime operation and a continuous 10 kW. demand for nighttime operation.

The overall system design developed in this thesis has an estimated total mass of 7,400 kg, when utilizing hydrogenated amorphous silicon thin film solar arrays and an estimated total mass of 5,100 kg when utilizing polycrystalline copper-indium-diselenide …

Interface Thermal Resistance Between Liquid Argon And Various Solids, Ziyuan Shi

Mechanical & Aerospace Engineering Theses & Dissertations

Heat conduction between two parallel solid walls separated by liquid argon is investigated using three-dimensional molecular dynamics (MD) simulations. Liquid argon molecules confined in silver and graphite nano-channels are examined separately. Heat flux and temperature distribution within the nano-channels are calculated by maintaining a fixed temperature difference between the two solid surfaces. Temperature profiles are linear sufficiently away from the walls, and heat transfer in liquid argon obeys the Fourier law. The temperature jump due to the interface thermal resistance (i.e., Kapitza length) is calculated by extrapolating the temperature profile in the bulk region on to the wall and is …

Characterizations Of Atmospheric Pressure Low Temperature Plasma Jets And Their Applications, Erdinc Karakas

Electrical & Computer Engineering Theses & Dissertations

Atmospheric pressure low temperature plasma jets (APLTPJs) driven by short pulses have recently received great attention because of their potential in biomedical and environmental applications. This potential is due to their user-friendly features, such as low temperature, low risk of arcing, operation at atmospheric pressure, easy handheld operation, and low concentration of ozone generation. Recent experimental observations indicate that an ionization wave exists and propagates along the plasma jet. The plasma jet created by this ionization wave is not a continuous medium but rather consists of a bullet-like-structure known as "Plasma Bullet". More interestingly, these plasma bullets actually have a …

Evaluation System Design And Academic Performance Analysis Using Clustering And Simulation, Volkan Cakir

Engineering Management & Systems Engineering Theses & Dissertations

The starting point of this study was to understand the possible causes of evaluation system change in a military academic environment. With that motivation the objectives of this study were defined as examining student profiles in a military academy, establishing the nature of academic performance, comparing student groups that were identified by course scores, analyzing student performance changes over time and developing a manageable evaluation system and curriculum by comparing different scenarios.

An analysis was performed on the literature on academic performance prediction, cluster analysis methodologies and their development, and specifically summarized cluster analytic academic performance studies where these two …

A Structured Project-Risk Management And Life Cycle Framework For Complex Systems: Ship Repair And Maintenance (Sr&M) Projects, Michael Craig Plumb

Engineering Management & Systems Engineering Theses & Dissertations

This dissertation contributes to insights regarding the implications of using Project Risk Management (PRM) and Life Cycle Assessment (LCA) in managing projects for a complex system. The PRM approach apprehends many forms of risk both internal and external within a given project and assists the manager in determining the level of importance of each individual project phase and component to optimize project success. The life cycle approach to project management is used with short-term limitations with respect to a product's life cycle over several years. The literature discusses many tools and techniques that assist project managers in implementing optimal solutions, …

Fusion Of Visual And Thermal Images Using Genetic Algorithms, Sertan Erkanli

Electrical & Computer Engineering Theses & Dissertations

Demands for reliable person identification systems have increased significantly due to highly security risks in our daily life. Recently, person identification systems are built upon the biometrics techniques such as face recognition. Although face recognition systems have reached a certain level of maturity, their accomplishments in practical applications are restricted by some challenges, such as illumination variations. Current visual face recognition systems perform relatively well under controlled illumination conditions while thermal face recognition systems are more advantageous for detecting disguised faces or when there is no illumination control. A hybrid system utilizing both visual and thermal images for face recognition …