Digital Commons Network^™

Improving Watershed Models Through Stakeholder Involvement, Laura Weintraub

Fifty Years Of Watershed Modeling - Past, Present And Future

No abstract provided.

A Distributed Watershed Hydrologic, Sediment, Nutrient Transport And Fate Model, Zhonglong Zhang, Billy E. Johnson, Charles W. Downer

Fifty Years Of Watershed Modeling - Past, Present And Future

No abstract provided.

Summary Of Comments By Panelist William James, Bill James

Fifty Years Of Watershed Modeling - Past, Present And Future

No abstract provided.

Estimating Statistical Characteristics Of Lognormal And Delta-Lognormal Distributions Under Interval Uncertainty: Algorithms And Computational Complexity, Nitaya Buntao, Sa-Aat Niwitpong, Vladik Kreinovich

Departmental Technical Reports (CS)

Traditional statistical estimates S(x₁, ..., x_n) for different statistical characteristics S (such as mean, variance, etc.) implicitly assume that we know the sample values x₁, ..., x_n exactly. In practice, the sample values Xi come from measurements and are, therefore, in general, different from the actual (unknown) values x_i of the corresponding quantities. Sometimes, we know the probabilities of different values of the measurement error d_i = X_i - x_i, but often, the only information that we have about the measurement error is the upper bound D_{i …}

Rapid, Large-Scale Production Of Full-Length, Human-Like Monoclonal Antibodies, Christopher M. Warner

KGI Theses and Dissertations

Current recombinant protein production systems require several months to develop. Existing systems fail to provide timely, flexible, and cost-effective therapies to protect against emergency mass-casualty infections or poisonings. As the identity of many new biological threat agents are unlikely to be known in advance, pre-emptive manufacturing and stockpiling of countermeasures cannot be performed. Preparedness for a biological catastrophe requires a radical solution to replace the current slow scale-up and manufacture of lifesaving medical countermeasures. Subunit vaccines and antibody fragments may be produced in bacteria, yeast, plant or insect cells. However, generation of full-length, human like glycosylated antibodies requires mammalian cell …

Feature-Based Neuro-Symbolic Networks For Global Diagnostics, Tracy Lynn Schantz

Electronic Theses and Dissertations

Engineered system diagnostics have been researched over the years with many successful results. From transportation systems to office technologies, many have been equipped with self-diagnostic capabilities and are called Smart Machines. In spite of these advances, current diagnostic systems are driven by direct sensory information without much concern for patterns of the system behavior or features associated with them. For large-scale systems with complex dynamics, global as well as local diagnostics become of great importance, where sensory information is used as input for the local diagnostics, and patterns of behavior or features are utilized for global diagnostics.

The main objective …

Micro Channel Cooler Performance Improvement By Insonation, Peter Webb Higgins

Electronic Theses and Dissertations

The motivation for this work is the need to remove waste heat from laser diodes and high speed transistors in processes which are exponentially increasing past 1 kW/cm2 as anticipated by Moore's Law. The hypothesis guiding the work is that ultrasonic insonation of micro coolers employed to dissipate these heat loads can improve heat removal. It is thought that the mechanism promoting the benefit is enhancement of the ability of the coolant to remove latent heat in two-phase operation by managing entrained bubble size near the cooler's exit so as to forestall flow reduction or blockage caused by large bubbles, …

Design Optimization Of Transistors Used For Neural Recording, E J. Basham, David W. Parent

Faculty Publications

Neurons cultured directly over open-gate field-effect transistors result in a hybrid device, the neuron-FET. Neuron-FET amplifier circuits reported in the literature employ the neuron-FET transducer as a current-mode device in conjunction with a transimpedance amplifier. In this configuration, the transducer does not provide any signal gain, and characterization of the transducer out of the amplification circuit is required. Furthermore, the circuit requires a complex biasing scheme that must be retuned to compensate for drift. Here we present an alternative strategy based on the design approach to optimize a single-stage common-source amplifier design. The design approach facilitates in circuit characterization of …

Regional Comparisons Of Nano-Mechanical Properties Of The Human Meniscus; Structure And Function, John Thomas Moyer

Dissertations, Master's Theses and Master's Reports - Open

Osteoarthritis (OA) is a debilitating disease that is becoming more prevalent in today’s society. OA affects approximately 28 million adults in the United States alone and when present in the knee joint, usually leads to a total knee replacement. Numerous studies have been conducted to determine possible methods to halt the initiation of OA, but the structural integrity of the menisci has been shown have a direct effect on the progression of OA. Menisci are two C-shaped structures that are attached to the tibial plateau and aid in facilitating proper load transmission within the knee. The meniscal cross-section is wedge-like …

2011/12 Research, Development, And Activities, College Of Engineering And Applied Sciences

Electrical and Computer Engineering Newsletter

• Dual-Use Ground Vehicle Condition Maintenance
• Nonlinear Circuits and Systems Laboratory
• Neurobiology Engineering Laboratory
• Storing Grid Power with Retired Electric Vehicle Batteries
• Stryker Challenge
• Tau Beta Pi
• Electrical and Computing Engineering Department Hosts Workshop for Mattawan Middle School Group
• Center for Advanced of Smart Sensors and Structures (CASSS)
• Sunseeker Displayed at Chrysler Technology Center

Predicting Speech Intelligibility, Andrew Hines [Thesis]

Other resources

Hearing impairment, and specifically sensorineural hearing loss, is an increasingly prevalent condition, especially amongst the ageing population. It occurs primarily as a result of damage to hair cells that act as sound receptors in the inner ear and causes a variety of hearing perception problems, most notably a reduction in speech intelligibility. Accurate diagnosis of hearing impairments is a time consuming process and is complicated by the reliance on indirect measurements based on patient feedback due to the inaccessible nature of the inner ear. The challenges of designing hearing aids to counteract sensorineural hearing losses are further compounded by the …

Fabrication And Testing Of Hierarchical Carbon Nanostructures For Multifunctional Applications, Ian Timothy Barney

Browse all Theses and Dissertations

Multi-scale hierarchical carbon structures have been developed by growing strongly attached carbon nanotubes (CNT) on high surface area substrates having open, interconnected porosity. This investigation was developed on cellular carbon foams but the process is equally suitable for other geometries including flat, fibers, and other porous substrates (interconnected). It is also adaptable to other substrate materials such as metals, alloys or ceramic compounds. Multiwalled carbon nanotubes are grown using a floating catalyst chemical vapor deposition (CVD) method after pre-coating the substrate with a silica nano-layer. The silica-coated graphitic substrates are seen to grow 280 times more nanotubes per unit area …

Santa Clara Magazine, Volume 53 Number 3, Winter 2012, Santa Clara University

Santa Clara Magazine

18 - MY FIGHT, MY FAITH By Steven Boyd Saum. As head of the CIA, Leon Panetta '60, J.D. '63 restored confidence in the agency and oversaw the mission to find Osama bin Laden. Now, as secretary of defense in an age of budget austerity, he has to make sure the Pentagon doesn't break the bank-and that the nation doesn't break faith with the men and women who serve.

24 - GENERAL JOE By Sam Scott '96. When Joseph Peterson '72 signed up for ROTC as an undergrad, he planned to complete his military service and then move on. Nearly …

Towards Symmetry-Based Explanation Of (Approximate) Shapes Of Alpha-Helices And Beta-Sheets (And Beta-Barrels) In Protein Structure, Jaime Nava, Vladik Kreinovich

Departmental Technical Reports (CS)

Protein structure is invariably connected to protein function. There are two important secondary structure elements: alpha helices and beta-sheets (which sometimes come in a shape of beta-barrels). The actual shapes of these structures can be complicated, but in the first approximation, they are usually approximated by, correspondingly, cylindrical spirals and planes (and cylinders, for beta-barrels). In this paper, following the ideas pioneered by a renowned mathematician M. Gromov, we use natural symmetries to show that, under reasonable assumptions, these geometric shapes are indeed the best approximating families for secondary structures.

Design And Experimental Validation Of Continuous Dna Separation Using Itp-Based Microfluidic Device, Nora C. M. Goscinski, Mary E. Rosa, Elizabeth K. Wheeler, Maxim Shusteff

Chemistry and Biochemistry

We have demonstrated a chip-based microfluidic device suitable for rapid and high-throughput DNA separation and purification for downstream analysis. The glass-based device incorporates a transverse free-flow isotachophoresis (tFF-ITP) that overcomes the volume limitations of CE approaches, and allows continuous sample processing in contrast to batch-mode solid-phase extraction (SPE). The device is able to focus DNA at flow rates up to 100 uL/min, and sample conductivity up to 2 mS/cm. Downstream of the chip, 30-40% of DNA from the input sample is recovered as a result of ITP focusing, and preliminary results indicate that this design is able to purify DNA …

Kinetic Models Of The Prebiotic Replication Of Dsrna Under Thermal Cycling Conditions, Pauline Schwartz, Dante M. Lepore, Carl Barratt

Chemistry and Chemical Engineering Faculty Publications

We present computational models for the replication of double stranded RNA (dsRNA) or related macromolecules under thermal cycling conditions that would reflect prebiotic (i.e. non-enzymatic) environments. Two models of the replication of dsRNA are represented as multi-step chemical systems. The objective of this investigation was to better understand the kinetic features of such chemical systems. It is shown that thermal cycling in a chemical system is advantageous (relative to a fixed temperature) if there are two competing reactions, one favored at high temperature and one favored at low temperature. For the prebiotic replication of dsRNA, a high temperature favors formation …

Service Life Prediction Of Residential Interior Finishes For Life Cycle Assessment, Can B. Aktas Ph.D.

Civil Engineering Faculty Publications

Service life of building products has an important influence on life cycle assessment (LCA) results of buildings. The goal of this study was to propose a systematic approach to estimate service life of building products by including both technical and social factors. A hybrid service life prediction method, combining the statistical approach described in American Society for Testing and Materials (ASTM) standard G166, with the Factor Method adopted by International Organization for Standardization (ISO) standard 15686 was proposed. In their current forms, the two methods are not suitable to provide accurate lifetime estimates for the wide variety of products that …

Santa Clara Magazine, Volume 54 Number 1, Summer 2012, Santa Clara University

Santa Clara Magazine

14 - BELLA VITA By Ron Hansen M.a. '95. After 66 years, Professor Victor Vari is retiring. He's imparted to generations of Santa Clara students an understanding of Italian language and culture-and how to live a beautiful life.

18 - THE SPORTING LIFE By Ann Killion. From when women first arrived on the Mission Campus 50 years ago and athletics was a dirty word-to internationally known programs and penalty shots heard 'round the world.

20 - RESPECT THE GAME By Britt Yap. They've been national champs and the subject of dreams-may-cometrue movies. But in the beginning, they were women who …

Santa Clara Magazine, Volume 54 Number 2, Fall 2012, Santa Clara University

Santa Clara Magazine

18 - WE, ROBOTS By John Deever. Adventures with the Robotics Systems Laboratory by land, sea, and sky. And in orbit.

20 - SARAH KATE WILSON VS. GODZILLA By Jeff Gire. Tackling big problems- like attracting more women to engineering and transferring mountains of data through the air.

22 - DELUGE AND DROUGHT By Erica Klarreich. Lessons in how to wedge more data into less space-and build a smarter energy grid.

24 - BUILDING BIOMEDICAL TESTS By Melissae Fellet. Where engineering meets biology, the work ranges from diagnosing voice disorders to tracking toxicity in the brain.

26 - THE LONG …

Santa Clara Magazine, Volume 53 Number 4, Spring 2012, Santa Clara University

Santa Clara Magazine

20 - WHAT WILL YOU BE? By David Mckay Wilson. San Francisco's Immaculate Conception Academy has found a work-study program that gives low-income students what they need. Starting with a bigger view of the world.

22 - BUCKY BRONCO CONFIDENTIAL By Jeff Gire And Sam Scott '96. Who wears the costume today may be classified information. But here are a few secrets revealed-including how Bucky came to be.

26 - TALKIN' DUST BOWL BLUES By David Mckay Wilson. The ghost of Woody Guthrie stalks the stage-with Rob Tepper '00 playing the role. This year marks the centennial of the iconic …

Cfd Study On Aerodynamic Effects Of A Rear Wing/Spoiler On A Passenger Vehicle, Mustafa Cakir

Mechanical Engineering Master's Theses

Aerodynamic characteristics of a racing car are of significant interest in reducing car-racing accidents due to wind loading and in reducing the fuel consumption. At the present, modified car racing becomes more popular around the world. Sports cars are most commonly seen with spoilers, such as Ford Mustang, Subaru Impreza, and Chevrolet Corvette. Even though these vehicles typically have a more rigid chassis and a stiffer suspension to aid in high-speed maneuverability, a spoiler can still be beneficial. One of the design goals of a spoiler is to reduce drag and increase fuel efficiency. Many vehicles have a fairly steep …

A Synthesis Of Rates And Controls On Elemental Mercury Evasion In The Great Lakes Basin, Joseph S. Denkenberger, Charles T. Driscoll, Brian A. Branfireun, Chris S. Eckley, Mark Cohen, Pranesh Selvendiran

Civil and Environmental Engineering - All Scholarship

Rates of surface-air elemental mercury (Hgo) fluxes in the literature were synthesized for the Great Lakes Basin (GLB). For the majority of surfaces, fluxes were net positive (evasion). Digital land-cover data were combined with representative evasion rates and used to estimate annual Hgo evasion for the GLB (7.7 Mg/yr). This value is less than our estimate of total Hg deposition to the area (15.9 Mg/yr), suggesting the GLB is a net sink for atmospheric Hg. The greatest contributors to annual evasion for the basin are agricultural (~55%) and forest (~25%) land cover types, and the open water of the Great …

Nutrient Supply And Mercury Dynamics In Marine Ecosystems: A Conceptual Model, Charles T. Driscoll, Celia Y. Chen, Chad R. Hammerschmidt, Robert P. Mason, Cynthia C. Gilmour, Elsie M. Sunderland, Ben K. Greenfield, Kate L. Buckman, Carl H. Lamborg

Civil and Environmental Engineering - All Scholarship

There is increasing interest and concern over the impacts of mercury (Hg) inputs to marine ecosystems. One of the challenges in assessing these effects is that the cycling and trophic transfer of Hg are strongly linked to other contaminants and disturbances. In addition to Hg, a major problem facing coastal waters is the impacts of elevated nutrient, particularly nitrogen (N), inputs. Increases in nutrient loading alter coastal ecosystems in ways that should change the transport, transformations and fate of Hg, including increases in fixation of organic carbon and deposition to sediments, decreases in the redox status of sediments and changes …

Shift Towards P Limitation With N Deposition?, K. F. Crowley, B. E. Mcneil, G. M. Lovett, C. D. Canham, C. T. Driscoll

Civil and Environmental Engineering - All Scholarship

Atmospheric nitrogen (N) deposition is altering biogeochemical cycling in forests and interconnected lakes of the northeastern US, and may shift nutrient limitation from N toward other essential elements, such as phosphorus (P). Whether this shift is occurring relative to N deposition gradients across the northeastern US has not been investigated. We used datasets for the northeastern US and the Adirondack sub-region to evaluate whether P limitation is increasing where N deposition is high at two geographic scales, based on N:P mass ratios. Using a model- selection approach, we determined that foliar N for dominant tree species and lake dissolved inorganic …

Nutrient Supply And Mercury Dynamics In Marine Ecosystems: A Conceptual Model, Charles T. Driscoll, Celia Y. Chen, Chad R. Hammerschmidt, Robert P. Mason, Cynthia C. Gilmour

Civil and Environmental Engineering - All Scholarship

There is increasing interest and concern over the impacts of mercury (Hg) inputs to marine 32 ecosystems. One of the challenges in assessing these effects is that the cycling and trophic 33 transfer of Hg are strongly linked to other contaminants and disturbances. In addition to Hg, a 34 major problem facing coastal waters is the impacts of elevated nutrient, particularly nitrogen 35 (N), inputs. Increases in nutrient loading alter coastal ecosystems in ways that should change 36 the transport, transformations and fate of Hg, including increases in fixation of organic carbon 37 and deposition to sediments, decreases in the …

Marine Mercury Fate: From Sources To Seafood Consumers, Celia Y. Chen, Charles T. Driscoll, Kathy Lambert, Robert P. Mason, Laurie Rardin

Civil and Environmental Engineering - All Scholarship

No abstract provided.

Biological Engineering: Advances And Methods, Joel Schwartz

The Science Journal of the Lander College of Arts and Sciences

The last few decades have seen a tremendous growth in the field of bioengineering. As the need for further treatment and innovation for tissue repair, partial to full organ replication, and gene therapy continues to increase, the field of bioengineering will be tasked with curing and preventing disease and traumatic injuries. The two primary fields currently being focused on in the lab are the way cells interact and communicate to build tissues, and the nature and materials utilized in scaffolding to allow differentiation and migration when cells are seeded. Within those two fields are subsets of different methods, materials that …

Modification Of Behavior Of Elastin-Like Polypeptides By Changing Molecular Architecture, Ali Ghoorchian

ETD Archive

Elastin-like polypeptides (ELP) are environmentally responsive polymers that exhibit phase separation in response to external stimuli such as temperature, pH, light, and ionic strength. It has been shown that the sequence of the pentapeptide, its length, and the solution concentration are very important in the transition of the molecules from soluble to insoluble, but there has not been any detailed study of the effect of molecular architecture on the behavior of ELPs.In this study we designed, synthesized and characterized ELPs with different architectures and chemical identities to probe the effect of molecular design on the microscopic and macroscopic behavior of …

Myocardial T1 Mapping Techniques For Quantification Of Myocardial Fibrosis, Xiaopeng Zhou

ETD Archive

Identifying and quantifying diffuse myocardial fibrosis is important to provide insights into the relationship between myocardial fibrosis, diastolic and systolic dysfunction, as well as clinical outcomes. T1 mapping is a promising technique for noninvasively identifying diffuse myocardial fibrosis in heart failure. A quantitative T1 map provides sensitivity to the full range of T1 values and is advantageous over the traditional T1-weighted imaging by reducing the reliance on visual interpretation of the signal intensity in the myocardium. However, in-vivo myocardial T1 quantification is challenging because of cardiac and respiratory motion. During the past few years, a variety of T1 mapping techniques, …

Effects Of Magnesium Sulfate, Digestate And Other Inorganic Nutrients On The Phototrophic Growth Of The Green Microalga Scenedesmus Dimorphus, Jacob R. Schwenk

ETD Archive

The individual components of the growth media, notably magnesium, have a profound impact on the growth and lipid production of the green microalgae, Scenedesmus dimorphus. The goal of this work was to investigate these effects and explain the causes via multiple experiments. It is important to understand the aspects of algal growth because they have a significant impact on the commercial viability of microalgal lipids as a potential feedstock for biofuel production. Digestate, derived from bovine waste and a potential cost effective nutrient replacement for conventional media types, was found to maximize growth and lipid concentration in S. dimorphus at …