Digital Commons Network^™

Visible Modulation Of Epsilon Near Zero Materials, Jonathan M. Weber

Theses and Dissertations

While Epsilon-Near-Zero materials have offered many benefits from their introduction to the field of nonlinear optics, those materials have also narrowed the range of wavelengths often studied. With reliable and proven enhancements to light-matter interaction in the ENZ region, many researchers have had little reason to extend the spectrum measured in experiments. The purpose of this work is to measure the intensity dependent refractive index of Indium Tin Oxide across a broad spectral range, from ultraviolet to near infrared, to improve the understanding of semiconductor nonlinearities far from Lorentz and Drude resonances. Furthermore, the visible region is naturally low-loss in …

Characterization Of Nanoplastic-Induced Exacerbation Of Asthmatic Pathophysiology In A Murine In Vivo Model, Keith Li

Theses and Dissertations

As global plastic production increases, so does the environmental and biological presence of nanoplastics (NPs), raising growing concerns about their potential impact on human health. These particles have been detected in various organs, including the lungs, yet their role in respiratory inflammation remains largely unexplored. Emerging evidence suggests that NP exposure may influence immune responses in the lungs, particularly in individuals with preexisting conditions such as asthma. However, the specific ways in which these particles interact with allergen driven inflammation are still unclear.

In this study, a murine model of allergic airway inflammation was used to investigate how surface modified …

Hypnosis And Mindfulness Audio Recordings For Reducing Fatigue In Individuals With Multiple Sclerosis: A Randomized Controlled Study, Mark P. Jensen, Susan Robles, Michael G. Nash, Susanne May, Dwan M. Ehde, Melissa A. Day, Owen Gottlieb, Laurence I. Sugarman, Kevin N. Alschuler

Articles

Background

Fatigue is a common problem in individuals with multiple sclerosis (MS).

Objective

The objective was to evaluate the effects on fatigue of having 4 weeks of

access to audio recordings of therapeutic hypnosis (HYP) and mindfulness meditation

(MM) practices.

Methods

A total of 333 individuals with MS and fatigue were randomly assigned to

one of the three treatment conditions for 28 weeks: (1) access to therapeutic HYP audio

recordings, (2) access to MM audio recordings, or (3) no access to recordings

(treatment as usual or TAU). Fatigue impact (primary outcome) and other outcomes

were assessed at 4, 16, and …

Catalytic Deoxygenation Of Oleaginous Biomass To Renewable Diesel And Sustainable Aviation Fuel Via Decarboxylation/Decarbonylation, Chukwudalu Great Umenweke

Theses and Dissertations--Chemistry

Several technologies have been developed to produce hydrocarbon biofuels – renewable diesel (RD) and sustainable aviation fuel (SAF) – from fats, oils, and greases (FOG), with the hydroprocessing of esters and fatty acids (HEFA) representing one of the most mature pathways. In its current form, HEFA is mainly reliant on the hydrodeoxygenation (HDO) reaction, which has several drawbacks since HDO requires large amounts and pressures of hydrogen, feedstocks of high purity and cost, as well as problematic sulfided catalysts that risk contaminating the biofuel product with sulfur. A process based on decarboxylation/decarbonylation (deCO_x) offers an attractive alternative to …

Piv Visualization Of A Sinusoidal Ehd Confinement Flow Induced By Variation In Ion Density For Electrostatic Particle Agglomeration, Md Eyasin Hossain

Graduate Research Theses & Dissertations

Long-term exposure to PM2.5, which is responsible for four million cardiovascular-related deaths worldwide, is a major concern as people spend 90% of their time indoors. Fabric filters have been commonly utilized for particle pollution control in indoor settings. However, the maintenance cost of fabric filters is relatively high, as particle accumulation on filters can lead to higher pressure drops (45 ∼ 300 Pa) and energy consumption, as well as the growth of biological organisms and the generation of airborne pathogens. An electrostatic precipitator (ESP) is filterless and widely used in the electric power industry for collecting coal fly ash. ESPs …

Leveraging Synthetic Data For Efficient Training Of Ai Models For Real-World Object Detection, Reinaldo A. Moraga

Graduate Research Theses & Dissertations

Modern computer vision (CV) systems largely depend on real-world data for training, which is costly in terms of time, materials, and resources. As industries push toward automation and Artificial Intelligence (AI) -driven solutions, the need for enabling more efficient model training is growing. The primary aim of this work is to explore a framework tailored for industrial applications that uses synthetic images generated from 3D models to train a CV model capable of real-world object detection. This approach seeks to reduce the time, cost, and resources typically required for training AI models with real-world data. This work presents a method …

Material And Mechanical Characterization Of Sla 3d Printed Graphene Nanoplatelet-Based Nanocomposites Fabricated Within A Magnetic Field, Soka Suliman

Graduate Research Theses & Dissertations

The process of utilizing a static magnetic field to fabricate a nanomaterial-based composite via a stereolithography (SLA) 3D printing process is still a relatively new approach within the field of additive manufacturing. By using this magnetic field during the 3D printing process, both material and mechanical properties can be oriented and axially varied for enhanced characteristics. In this investigation, between 0% to 2% volume fractions of high aspect ratio, graphene nanoplatelets (GNP) are suspended within UV-curable resin during a SLA 3D printing process with a static magnetic field applied. The objective of this investigation is to determine the effect of …

Pre-Programmable Directional Stiffness In Continuum Robotic Arms: Effects Of Truss Configurations, Mostafa Abdelaziz, Zahy Elgendy, Mahmoud Magdy

Mechanical Engineering

This paper investigates the implementation of trussed designs in modular tendon-driven continuum arms (CAs) to address stiffness and stability limitations while maintaining adaptability. Various truss configurations— Single-Level, Combined-Level, and Alternated trusses—were analyzed using Finite Element Analysis (FEA) to evaluate their impact on flexural and axial stiffness under realistic loading conditions. Results demonstrate that truss placement significantly influences performance, with bottom-level trusses improving flexural stiffness by up to 33%, middle-level trusses enhancing axial stiffness by 43%. Further, Combined-Level configurations provide superior overall stiffness, with MiddleBottom trusses achieving a 66.5% improvement in flexural stiffness and a 70.9% increase in axial stiffness, while …

Climate Variability Study For Arid Regions, Faisal Almutairi

Electronic Theses and Dissertations

Water is the primary source for all living species to thrive, and water scarcity has been a primary concern for biological species and plants in arid regions due to urban planning, population growth, poor water management, and overgrazing. The objective of this research was to study the climate variability in precipitation and temperature for an arid region. This research encompasses two distinct studies. The first study examined the impact of climate variability on precipitation in Phoenix. Precipitation data were acquired from NOAA from 1948 to 2023 and the study was broken down into three time scales: annually, seasonally, and monthly. …

Biopolymer-Induced Soil Ductility Enhancement: Mitigating The Effects Of Desiccation Cracks, Rabindra Prasad Bohara

Electronic Theses and Dissertations

This study addresses the formidable challenges of expansive clayey soils, notorious for their swelling-shrinkage characteristics, which often lead to ground instability and structural damage. While effective in mitigating soil swell-shrink potential and enhancing strength, traditional calcium-based stabilizers can react with higher sulfate content to form ettringite, causing volumetric changes and infrastructure distress. To assess the impact of stabilizing sulfate-rich soils and determining the various engineering properties, samples of both control and stabilized soils were prepared using lime, biopolymer (guar gum), and lime with guar gum at concentrations of 2% and 4% lime only, 0.5%, 1% and 1.5% guar gum only, …

Development Of A Collagen-Based Bioink For 3d Printing Biomimetic Tendon-To-Bone Tissue Grafts For Rotator Cuff Repair, Samiul Nibir

Electronic Theses and Dissertations

This study presents the development of a collagen-based bioink for 3D printing tendon-to-bone tissue grafts, specifically designed for rotator cuff repair applications. Three different bioink formulations were developed: (i) 5.1% (w/v) collagen I, (ii) 5% (w/v) collagen I and collagen II, and (iii) 4.5% (w/v) collagen I combined with β-TCP. The bioink containing collagen I and collagen II was prepared by mixing the two components in a 1:1 ratio, while the collagen I plus β-TCP formulation was made by incorporating 20 wt % β-TCP into the collagen I solution. These formulations were developed to replicate the natural tendon-to-bone complex interface …

Modeling Fluid Flow In Complex Biological Systems: Implications For Dense Tumor Microenvironments, Metastasis, And Bone Cancer, Mohammad Mehedi Hasan Akash

Electronic Theses and Dissertations

The transport of biofluids in physiological systems plays a critical role in understanding and optimizing therapeutic interventions for diseases such as cancer and respiratory infections. This dissertation focuses on developing and validating a comprehensive computational framework for studying multiphase transport in complex biological environments. The research emphasizes the use of Computational Fluid Dynamics (CFD) to simulate and analyze plasma perfusion in solid tumors, particle deposition in respiratory airways, and fluid transport in cancer metastasis and bone cancer systems. By addressing the challenges of modeling biological transport phenomena, this work provides valuable insights into therapeutic planning and experimental validation. The study …

Semantic Think-On-Graph (Semtog) : Enhancing Graphrag Through Semantic Community Detection, Sugam Mishra

Electronic Theses and Dissertations

Graph-based Retrieval-Augmented Generation (GraphRAG) enhances large language models (LLMs) by grounding their reasoning in structured knowledge graphs, making them more reliable for multi-hop reasoning and factual QA. A central mechanism in Think-on-Graph systems such as ToG[14] and FastToG[7] is community detection, which groups locally related nodes into compact subgraphs so that LLMs can reason over focused, information-rich neighborhoods instead of traversing the entire graph. However, these methods rely purely on structural connectivity, often scattering semantically related entities across different communities and weakening the evidence provided to the LLM. We propose Semantic Think-on-Graph (SemToG), a semantic-aware extension of FastToG[7] that integrates …

Multi-Source Remote Sensing–Based Soil Moisture Prediction Using Machine Learning, Niraj Neupane

Electronic Theses and Dissertations

Soil moisture (SM) plays a central role in climatic and environmental processes, influencing shear strength of soil, agricultural productivity, land–atmosphere interactions, and hydrologic functioning. However, accurately estimating SM across diverse climatic regions remains challenging due to spatial heterogeneity, limited in situ measurements, and inconsistencies in sensor resolution. Machine learning (ML) and remote sensing offer promising avenues for improving SM prediction, yet many existing approaches struggle with generalization across climatic gradients and often fail to capture temporal variability. This study integrates multi-source satellite and climate datasets, including SMAP L4_SM, MODIS land surface temperature, Daymet meteorological variables, and in situ observations from …

Intercellular Mitochondrial Transfer Contributes To Microenvironmental Redirection Of Cancer Cell Fate, Julie Sofie Bjerring, Yara Khodour, Emilee Anne Peterson, Patrick Christian Sachs, Robert David Bruno

School of Medical Diagnostics & Translational Sciences Publications

The mammary microenvironment has been shown to suppress tumor progression by redirecting cancer cells to adopt a normal mammary epithelial progenitor fate in vivo. However, the mechanism(s) by which this alteration occurs has yet to be defined. Here, we test the hypothesis that mitochondrial transfer from normal mammary epithelial cells to breast cancer cells plays a role in this redirection process. We evaluate mitochondrial transfer in 2D and 3D organoids using our unique 3D bioprinting system to produce chimeric organoids containing normal and cancer cells. We demonstrate that breast cancer tumoroid growth is hindered following interaction with mammary epithelial cells …

Benchmarking Batch-Effect Correction Methods Towards The Construction Of A Triple-Negative Breast Cancer Cell Atlas, Peter Scheible, Amy H. Tang, Jing He, Jiangwen Sun

Computer Science Faculty Publications

Triple-negative breast cancer (TNBC) requires detailed cellular mapping given its aggressive nature, immense tumor heterogeneity and genetic diversity. We integrated 156,794 cells from six scRNA-seq datasets—including tumors, metastases, and cell lines—to build a TNBC scRNA cell atlas, focusing on batch effect mitigation while maintaining biological and molecular details. Preprocessing f ilters noise, normalizes data, and leverages PCA for integration readiness. We utilized scANVI, a semi-supervised tool, to align datasets, preserving TNBC’s complex tumor heterogeneity via marker annotations [1]. UMAPs demonstrate biological clustering in integrated data, contrasted with datasetdriven unintegrated patterns. Assessments verifying effective batch correction. This method aligns with NASA’s …

Coldstartcpi: Induced-Fit Theory-Guided Dti Predictive Model With Improved Generalization Performance, Qichang Zhao, Haochen Zhao, Linyuan Gao, Kai Zheng, Yajie Li, Qiao Ling, Jing Tang, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Predicting compound-protein interactions (CPIs) plays a crucial role in drug discovery. Traditional methods, based on the key-lock theory and rigid docking, often fail with novel compounds and proteins due to their inability to account for molecular flexibility and the high sparsity of CPI data. Here, we introduce ColdstartCPI, a framework inspired by induced-fit theory, which leverages unsupervised pre-training features and a Transformer module to learn both compound and protein characteristics. ColdstartCPI treats proteins and compounds as flexible molecules during inference, aligning with biological insights. It outperforms state-of-the-art sequence-based models, particularly for unseen compounds and proteins, and shows strong generalization capability …

Ecobuoys For Scalable Oceanography, Anuscheh Nawaz, Michael Steele, Ruth Branch, David Burnett, Kuotian Liao, Mallory Parker, Eleftheria Roumeli

Electrical and Computer Engineering Faculty Publications and Presentations

An approach to scalable surface-drifting buoys is needed to enable the high spatial and temporal resolution of oceanographic data that the science and meteorological communities are asking for. With the number of active buoys predicted to increase by a factor of 100 or more, the impact on the environment becomes even more important. Here, we present a pathway to a scalable and sustainable generation of buoys. We identify the main criteria to be used when developing such buoys to be low cost, with reliable data and neutral or even positive environmental impact. For each buoy subsystem—hull, electronics, energy generation and …

Evaluation Of The Dnazyme Gr5 For The Determination Of Lead Speciation In Natural Waters, Gaganprit Gill

Theses and Dissertations (Comprehensive)

This thesis explores the development and application of a DNAzyme-based biosensor designed to detect labile metal species in environmental samples. Real time and on-site monitoring of labile metal fractions would make a valuable contribution to environmental management, as these fractions are the most bioavailable and pose significant toxicity risks to aquatic organisms. Conventional methods for detecting labile metals, while effective, are often burdened by high costs, complexity, and lengthy processing times, making them less ideal for rapid and widespread environmental assessments.

The first manuscript of this thesis (chapter 2) establishes the fundamental capabilities of the Pb²⁺-specific DNAzyme GR5 …

Bibliometric And Visualisation Analysis Of Biomass Burning Research In Thailand (1997-2024), Weerachon Sawangproh, Arika Bridhikitti

Applied Environmental Research

Biomass burning is a major driver of air pollution and climate-related impacts in Thailand, but a national-level synthesis of research efforts is lacking. This study conducts a comprehensive bibliometric and qualitative review of 256 peer-reviewed publications from 1997–2024, using Scopus-indexeddata to explore research trends, thematic patterns, and existing gaps. The analysis reveals a strong emphasis on atmospheric chemistry, air quality modeling, and remote sensing, which collectively account for more than 60% of the research landscape.Studies frequently focus on pollutants such as PM2.5,PAHs, carbon monoxide, and heavy metals, with biomass burning identified as a dominant source, especiallyduring the dry season in …

Quantifying Biodiversity In The Absence Of Taxonomic Data: A Study Of Thailand’S Economic Development Zones, Nikorn Mahawan, Wanpen Charoentrakulpeeti

Applied Environmental Research

The biodiversity status measures the ecological capacity of a given area. However, biodiversity assessments in developing countries are limited by the absence of taxonomic data on plants and animals. By developing methods to evaluate biodiversity via alternative data, it is now possible to quantify the ecological carrying capacity in areas where taxonomic data are lacking. The relationship between forest ecosystem health and biodiversity values can be used to estimate biodiversity values by considering the proportions of different land use types that are associated with forest ecosystem abundance. The biodiversity value of the area can be assessed by adding the abundance …

Spatial And Temporal Dynamics Of Water Use Efficiency And Climate Influence In The Central Highlands Of Vietnam Via Satellite Time Series, Thi Nguyen Quang, Hoang Van Hung

Applied Environmental Research

This study investigates the spatial and temporal patterns of water use efficiency (WUE) anomalies across the Central Highlands of Vietnam from 2001–2024 via MODIS time series data, with a focus on seasonal differences and climatic drivers. The results revealed pronounced interannual and spatial variability in the WUE, with significant improvements observed during 2004, 2015, and 2021–2024 and substantial declines during 2005–2008, 2010–2013, and 2016–2017, which coincided with major drought events in the region. Seasonal analysis indicated that WUE was lower during the early dry season and peaked during the postmonsoon months (October–November), reflecting the interplay between water availability and vegetation …

Using A Water Quality Index To Assess The Impacts Of Heavy Metals Contamination For Sustainable Water Management: A Case Study Of The Bang Pakong River, Thailand, Khin Yadana Soe, Pokchat Chutivisut, Wilailuk Niyommaneerat

Applied Environmental Research

Anthropogenic activities such as improper waste disposal, excessive fertilizer use, and industrial effluents cause heavy metal contamination in water, soil, and the atmosphere. Herein, the water quality index (WQI) was used to characterize heavy metal (i.e., cadmium (Cd), arsenic (As), and mercury (Hg)) contamination in the Bang Pakong River, Thailand. Specifically, water samples were collected during the dry season from four stations along the river from 2012–2022. The heavy metal concentrations in the samples were analyzed via atomic absorption spectrophotometry, and WQI values were calculated on the basis of standard water quality parameters. At the four sampling stations, high As …

Halotolerant Biodegradation And Detoxification Of Synthetic Dyes By Marine-Derived Penicillium Oxalicum M6a: Metabolite Profiling And Ecotoxicity Assessment, Ugochukwu Okechukwu Ozojiofor, Mohammed Sani Abdulsalami, Nkechi Eucharia Egbe, Ahmed Ali Haroun, Yakubu Magaji

Applied Environmental Research

The complex aromatic structures of synthetic dyes in contaminated water bodies make them difficult to degrade, posing a serious environmental challenge and representing a significant emerging pollutant that warrants urgent intervention. This study evaluated the biodegradation and detoxification potential of a halotolerant, marine-derived fungal strain, Penicillium oxalicum M6A, isolated from the Nigerian coastline, against Indigo carmine (IC) and Remazol Brilliant Blue R (RBBR). The effects of pH, temperature, salinity, and dye concentration on degradation efficiency, alongside enzymatic activity, were assessed. FTIR and GC‒MS analyses were employed to identify degradation products and predict metabolic pathways, whereas toxicity was evaluated in three …

Blue Carbon Stock Assessment Of The Mangrove Swamp Forest Reserve In Baganga, Davao Oriental, Philippines, Renz Morales Lanaban, Yves Paul M. Montero, Hilario L. Wong, Jr., Marnie Grace I. Sonico

Applied Environmental Research

Mangrove ecosystems are vital carbon sinks, yet they are threatened by anthropogenic pressures and natural disturbances, causing significant carbon stock losses. Given the limited data for Baganga, Davao Oriental, this study quantified the aboveground biomass (AGB) and blue carbon stock in the Lucod mangrove swamp forest reserve. We identified mangrove species, measured AGB and carbon content via allometric equations, and compared storage among species. The results indicated that the mangrove forest AGB was within typical ranges for tropical wet regions and the Asia-Pacific region, but its overall carbon content did not reach highly productive ecosystem levels. Nonparametric analysis revealed significant …

Spatial Distribution And Potential Ecological Risk Of Microplastics In Surface Sediments Of The Inner Gulf Of Thailand, Sarayut Suanluang, Pathompong Vibhatabandhu, Sarawut Srithongouthai

Applied Environmental Research

The global surge in plastic usage during the COVID–19 pandemic raised concerns about increased microplastic (MP) contamination in aquatic environments. This study assessed the abundance, characteristics, and ecological risk of MPs in surface sediments of the inner Gulf of Thailand during the post–COVID–19 period (April 2021). The sediment samples were analyzed via density separation, stereomicroscopic examination, and polymer identification via micro–FTIR. The mean MP abundance was 196.07 ± 85.60 pieces kg-1, with concentrations ranging from 73.08 to 351.19 pieces kg-1. PTFE and PP were the dominant polymer types, comprising 50% and 32% of all the MPs, respectively. Fibers (34%) and …

Health Risk Assessment Of Copper Exposure Through Hand-To-Mouth Activities In The Lithium-Ion Battery Manufacturing Industry, Adisorn Phungkum, Worawat Meevasana, Khanidtha Marungrueang

Applied Environmental Research

This study aims to evaluate the occupational exposure levels of copper (Cu) among workers in a battery manufacturing facility by analyzing the Cu concentrations on hand surfaces at three distinct time periods: before work (BW), before lunch (BL), and after work (AW). A total of 30 workers involved in 13 different workstations or tasks—such as battery cell preparation, spot welding, soldering, and labeling—were included in the study to reflect diverse exposure scenarios. Surface wipe sampling was conducted according to NIOSH Method 9102, and the Cu concentrations were quantified via inductively coupled plasma‒mass spectrometry (ICP‒MS). Additionally, the hazard quotient (HQ) was …

Spatial Estimation Of Trophic State For Reservoir Using Ground Monitoring And Remote Sensing Data, Thong Nguyen Hoang, Van Tran Thi

Applied Environmental Research

Nutrient pollution, also known as eutrophication, is a severe environmental problem that leads to harmful algal blooms in water bodies and affects water supplies for human use. This study aims to determine the trophic state of the reservoir based on the trophic state index (TSI) calculated from ground monitoring data of Secchi depth (SD), total phosphorus (TP), and chlorophyll-a (Chl-a) obtained from 35 points in 2 survey periods during the late rainy season to early dry season 2012–2013 and May 2023. In addition, we combined remote sensing data to spatially estimate the eutrophication situation across the reservoir through correlation analysis …

Efficient Oxidation Of Methylene Blue Via Catalytic Activation Of Peroxymonosulfate Via An Engineered Δ-Feooh/Pili Nutshell Biochar Composite, Lorenz Borromeo

Applied Environmental Research

This study introduces a novel composite catalyst formed by anchoring delta iron oxyhydroxide (δ-FeOOH) onto pyrolyzed Pili nutshell biochar via a room-temperature coprecipitation technique, marking the first application of Pili nutshell waste in advanced oxidation processes for wastewater treatment. This innovative methodology enhances catalyst dispersion and stability, facilitating the activation of peroxymonosulfate (PMS) to generate reactive sulfate radicals (SO4•–) for the degradation of methylene blue (MB), a thiazine dye commonly used in the medical field and the dye industry. Different techniques have been used to characterize synthesized composites in terms of their morphology, elemental composition, surface functional groups, and crystalline …

Assessment Of The Carbon Stock Of Trees In Selected Urban Green Spaces Of Davao City, Philippines, Daiseree Cuabo, Yves P.M. Montero, Daryl S. Salas, John P.M. Viernes

Applied Environmental Research

The combined impacts of deforestation, tree cover loss, and urbanization in urban and suburban areas significantly reduce the capacity of natural carbon sinks to sequester and store carbon. Hence, this study assessed the aboveground biomass (AGB) and carbon stock of trees in the selected green spaces of Davao City. A purposive sampling technique was employed in placing quadrats, with data collected from 27 plots categorized by size. AGB was estimated via an allometric equation, and aboveground carbon (AGC) was derived from the AGB values. A total of 358 individual trees from 25 species, 24 genera, and 13 families were documented. …