Digital Commons Network^™

Real-Time Optical Monitoring Of Endotracheal Tube Displacement, Ramzan Ullah, Karl Doerfer, Pawjai Khampang, Faraneh Fathi, Wenzhou Hong, Joseph E. Kerschner, Bing Yu

Biomedical Engineering Faculty Research and Publications

Proper ventilation of a patient with an endotracheal tube (ETT) requires proper placement of the ETT. We present a sensitive, noninvasive, operator-free, and cost-effective optical sensor, called Opt-ETT, for the real-time assessment of ETT placement and alerting of the clinical care team should the ETT become displaced. The Opt-ETT uses a side-firing optical fiber, a near-infrared light-emitting diode, two photodetectors with an integrated amplifier, an Arduino board, and a computer loaded with a custom LabVIEW program to monitor the position of the endotracheal tube inside the windpipe. The Opt-ETT generates a visual and audible warning if the tube moves over …

Gan Nanowire Laser For A Universal Atomic Force Microscope Probe: A Computational And Feasibility Study, Neal Wostbrock

Nanoscience and Microsystems ETDs

This thesis attempts to establish the groundwork for integrating a GaN nanowire into an AFM probe resulting in a universal atomic force microscope probe. Previous studies have shown GaN nanowires have stable mechanical properties, can be fabricated at scale with high aspect ratios and very smooth side walls, and have intrinsic lasing capabilities; however, mechanical and lasing capabilities have not yet been integrated into a single AFM probe. Here, we develop and analyze a suspended waveguide optical pumping concept that can be fabricated and applied to an AFM probe cantilever, unlocking full potential of GaN’s optical and mechanical properties as …

Incorporation Of Lignin In Natural And Synthetic Biomaterials To Alter Mechanical And Biochemical Properties For Enhanced Wound Healing, Jorge Alfonso Belgodere

LSU Doctoral Dissertations

It is estimated that chronic, non-healing wounds affect more than 6.5 million Americans annually, with an estimated healthcare cost beyond $14 billion. Here, we attempted to create composites of natural (collagen type I or gelatin-methacrylate) or synthetic (poly(ethylene glycol) polymers incorporating a natural plant component, lignin, to combat the costs and limitations current wound healing methods face. Three-dimensional matrices of collagen type I (Col I) are widely used in tissue engineering applications for its abundance in many tissues, bioactivity with many cell types, and excellent biocompatibility. Inspired by the structural role of lignin in plant tissue, we found that sodium …

Effective Hair Styling Compositions And Processes, Yiqi Yang, Helan Xu, Kaili Song

Department of Textiles, Merchandising and Fashion Design: Faculty Publications

This disclosure relates to hair styling compositions and processes , and more particularly to compositions for disentangling or crosslinking hair that are useful in hair styling processes.

Formal Concept Analysis Applications In Bioinformatics, Sarah Roscoe

School of Computing: Dissertations, Theses, and Student Research

Bioinformatics is an important field that seeks to solve biological problems with the help of computation. One specific field in bioinformatics is that of genomics, the study of genes and their functions. Genomics can provide valuable analysis as to the interaction between how genes interact with their environment. One such way to measure the interaction is through gene expression data, which determines whether (and how much) a certain gene activates in a situation. Analyzing this data can be critical for predicting diseases or other biological reactions. One method used for analysis is Formal Concept Analysis (FCA), a computing technique based …

A Framework For Assessing The Reliability, Availability, Maintainability, And Safety (Rams) Of Decentralized Sanitation, Adefunké Adeosun

USF Tampa Graduate Theses and Dissertations

In established industry sectors, Reliability, Availability, Maintainability, and Safety (RAMS) risk assessments are normally used to compare the risks associated with different technologies on process units. Sanitation solutions are split into traditional wastewater treatment which is centralized treatment and can be classified as an established industry, and decentralized treatment such as pit latrines and septic tank systems which are on much smaller scales. Also they can be classified as non-conventional methods such as reinvented advanced decentralized non-sewered sanitation solution techniques exist mainly in two forms as “Single-User Reinvented Toilet (SURT)” systems or “Multiple-User Reinvented Toilet (MURT)” systems. Advanced decentralized non-sewered …

Coral Reef Restoration In The Tropical West Atlantic Amid The Covid-19 Pandemic, Linden Cheek

USF Tampa Graduate Theses and Dissertations

Climate change is increasing threats to coasts, both from storm surge and sea level rise. Healthy coral reefs provide reduction in storm surges, wave energy, coastal flooding and everyday erosion, and are found across a variety of spatial scales. Given the state of coral reefs worldwide, active Coral Reef Restoration (CRR) in emerging as a necessary component of coastal protection. CRR can be classified as a nature-based solutions (NbS) for coastal protection that also provides a multitude of ecosystem-based services to both humans and other life. Nearly all literature on coral restoration efforts assume a steady-state of human-ecological interactions, but …

Opto-Fluidic Manipulation Of Microparticles And Related Applications, Hao Wang

USF Tampa Graduate Theses and Dissertations

Contemporary biomedical technologies introduce many new instruments that are important for diagnosis and treatment of the patients. Instrument that can do rapid detection of bacterial infections, and further direct medical practitioner to prescribe optimal antibiotics is highly desirable. But unfortunately, this instrument is not available yet. Ideally, this instrument has to be portable to be used at point-of-care. This means it has to be small and inexpensive, but still highly accurate. Another critical requirement for the instrument is that the test results have to be available promptly. Because in case of such complications of bacterial infections as sepsis, each additional …

Urine Volume Reduction During Long-Duration Cave Exploration By A Light-Weight And Portable Forward Osmosis System, Sebastian Engelhardt, Katey E. Bender, Jörg Vogel, Stephen E. Duirk, Francisco B. Moore, Hazel A. Barton

International Journal of Speleology

The preservation of caves is a challenge during long-duration cave expeditions where human waste can add significant nitrogen to the cave ecosystem. Since the removal of urine that accumulates during a multi-day caving trip is not always feasible due to weight and volume constraints, a light-weight and portable filtration system that is capable of reducing urine volume would be desirable. In this study we tested the Aquaporin Inside hollow fiber membrane in a forward osmosis (FO) setup to evaluate its capability to reduce urine volume while rejecting nitrogenous compounds using different draw solution chemistries and water recovery rates. As a …

Be Students Engage With Industry Leaders At Virtual Conference, Usu College Of Engineering

College of Engineering News

Nov. 9, 2020 — The Biological Engineering Department hosted its third annual Intermountain Biological Conference on Oct. 30 and 31. This year’s theme was Biological Engineering’s Impact on Public Health. Featured speakers came from industry partners and government agencies. The event was held virtually due to COVID-19 restrictions. For the poster session, students were required to submit a video explaining their research along with a digital poster.

Recent Advances In Reducing Food Losses In The Supply Chain Of Fresh Agricultural Produce, Daniel I. Onwude, Guangnan Chen, Nnanna Eke-Emezie, Abraham Kabutey, Al Fadhl Yahya Al Khaled, Barbara Sturm

Biosystems and Agricultural Engineering Faculty Publications

Fruits and vegetables are highly nutritious agricultural produce with tremendous human health benefits. They are also highly perishable and as such are easily susceptible to spoilage, leading to a reduction in quality attributes and induced food loss. Cold chain technologies have over the years been employed to reduce the quality loss of fruits and vegetables from farm to fork. However, a high amount of losses (≈50%) still occur during the packaging, transportation, and storage of these fresh agricultural produce. This study highlights the current state-of-the-art of various advanced tools employed to reducing the quality loss of fruits and vegetables during …

Ensemble Labeling Towards Scientific Information Extraction (Elsie), Erin Murphy

College of Computing and Digital Media Dissertations

Extracting scientific facts from unstructured text is difficult due to challenges specific to the ambiguity of the language, the complexity of the scientific named entities and relations to be extracted. This problem is well illustrated through the extraction of polymer names and their properties. Even in the cases where the property is a temperature, identifying the polymer name associated with the temperature may require expertise due to the use of acronyms, synonyms, complicated naming conventions and by the fact that new polymer names are being “introduced” to the vernacular as polymer science advances. While there exist domain-specific machine learning toolkits …

Nmr Spectroscopy Analysis Reveals Differential Metabolic Responses In Arabidopsis Roots And Leaves Treated With A Cytokinesis Inhibitor, Thomas E. Wilkop, Minmin Wang, Angelo Heringer, Jaideep Singh, Florence Zakharov, Viswanathan V. Krishnan, Georgia Drakakaki

Physiology Faculty Publications

In plant cytokinesis, de novo formation of a cell plate evolving into the new cell wall partitions the cytoplasm of the dividing cell. In our earlier chemical genomics studies, we identified and characterized the small molecule endosidin-7, that specifically inhibits callose deposition at the cell plate, arresting late-stage cytokinesis in arabidopsis. Endosidin-7 has emerged as a very valuable tool for dissecting this essential plant process. To gain insights regarding its mode of action and the effects of cytokinesis inhibition on the overall plant response, we investigated the effect of endosidin-7 through a nuclear magnetic resonance spectroscopy (NMR) metabolomics approach. In …

Chicoreus Brunneus Seashells As A Catalyst In Rice Bran Biodiesel Production, Hoora Mazaheri

Student Works (2020-2029)

Environmental pollution and the declining global supply of accessible fossil fuels are the key drivers to search for alternative energy sources. This study focused on developing a “green” and sustainable heterogenous calcium oxide (CaO) catalyst from Chicoreus Brunneus shells for biodiesel production from rice bran oil (RBO). Coastal people frequently collect these shells for food and shell crafts. Thus, by using seashell wastes, cost-efficient catalysts can be achieved for the biodiesel industry. The shells were calcinated, washed and dried to produce pure CaO catalyst. After that, CaO was converted into calcium methoxide (Ca(OCH3)2) and followed by loading onto zeolite support …

Centrifugal Microfluidic Platform For Solid-Phase-Extraction (Spe) And Fluorescence Detection Applications, Yong Zhang

LSU Doctoral Dissertations

Solid phase extraction (SPE) is a widely used method to separate and concentrate the target molecules in liquid mixture. Traditional SPE has to be conducted in the laboratory with professional equipment and skilled operators. The microfluidic and 3D printing technology have opened up the opportunity in developing miniaturized automatic instruments. The main contribution of this research is to integrate the SPE process on a novel centrifugal platform. Various valves are applied on the platform to help control the aqueous sample and reagents in the cartridge.

First, a centrifugal microfluidic platform was built for automatically detecting trace oil pollution in water. …

P-Cresol Biogenesis During Bioremediation Aimed At Stimulating Chlorinated Solvent Dehalogenation, Alexis Gathings

LSU Master's Theses

The broad goal of the research described in this thesis was to better understand the potential for biologically mediated production of p-cresol in groundwater at a Superfund site located in south Louisiana. Previous literature reports that microorganisms known to carry out the transformation from L-tyrosine to p-cresol occur in diverse environments.

In the research described in this thesis, studies were conducted utilizing groundwater from the Superfund site during the course of enhanced in situ bioremediation practices aimed at stimulating reductive dehalogenation of chlorinated solvent contamination. Microbial communities established with groundwater sampled from the Superfund site were observed to …

Proposal For The Development And Addition Of A Cybersecurity Assessment Section Into Technology Involving Global Public Health, Stanley Mierzwa, Bok Gyo Jeong, Claire Yun

Center for Cybersecurity

This paper discusses and proposes the inclusion of a cyber or security risk assessment section during the course of public health initiatives involving the use of information and communication computer technology. Over the last decade, many public health research efforts have included information technologies such as Mobile Health (mHealth), Electronic Health (eHealth), Telehealth, and Digital Health to assist with unmet global development health needs. This paper provides a background on the lack of documentation on cybersecurity risks or vulnerability assessments in global public health areas. This study suggests existing frameworks and policies be adopted for public health. We also propose …

Enhancing The Visibility Of Vernier Effect In A Tri-Microfiber Coupler Fiber Loop Interferometer For Ultrasensitive Refractive Index And Temperature Sensing, Fangfang Wei, Dejun Liu, Zhe Wang, Zhuochen Wang, Gerald Farrell, Qiang Wu, Gang-Ding Peng, Yuliya Semenova

Articles

In this paper a Vernier effect based sensor is analyzed and demonstrated experimentally in a tri-microfiber coupler (Tri-MFC) and polarization-maintaining fiber (PMF) loop interferometer (Tri-MFC-PMF) to provide ultrasensitive refractive index and temperature sensing. The main novelty of this work is an analysis of parameters of the proposed Tri-MFC-PMF with the objective of determining the conditions leading to a strong Vernier effect. It has been identified by simulation that the Vernier effect is a primary factor in the design of Tri-MFC-PMF loop sensing structure for sensitivity enhancement. It is furthermore demonstrated experimentally that enhancing the visibility of the Vernier spectrum in …

A Markov Chain Approach For Forecasting Progression Of Opioid Addiction, Abhijit Gosavi, Susan L. Murray, N. Karagiannis

Engineering Management and Systems Engineering Faculty Research & Creative Works

The U.S. is currently facing an opioid crisis. Naltrexone is a common treatment for drug addiction; it reduces the desire to take opiates. However, addicts often stop treatment or continue to use opioids while in treatment. This results in increased fatalities and associated costs. A Markov-chain model is presented to analyze the progression of opioid addiction to assist the medical community in developing appropriate treatments. The model includes patients who continue opiate use while on naltrexone (blocked patients) and those who use opiates after missing naltrexone doses (unblocked patients). The other types of patients are abstinent (the best-case scenario) and …

Fabrication And Characterisation Of Highly Aligned Fibrous Assemblies, Tan Chin Joo

Student Works (2020-2029)

Vascular grafting has been an effective remedy to vascular diseases for decades. Autografting by using the veins or arteries in the patient’s body is found to have patency rate for years. However, autografting may not be possible when compatible vessels are not available. In this case, synthetic vascular grafts are found to be effective replacements. Nevertheless, synthetic grafts with diameter less than 4 mm becomes challenging due to thrombogenicity and mismatch of mechanical properties with the native vessels. Along this line, the ability to develop new biostable synthetic materials suitable for smaller grafts and the ability to evaluate their resulting …

Effect Of Landfill Leachates On Some Water Quality Indicators Of Selected Surface Water And Groundwater At Ilokun, Ado-Ekiti, Nigeria, Olorunwa Omofunmi, Adesola Satimehin, Abraham Oloye, Okwunna Umego

Makara Journal of Technology

This study was conducted to examine the impact of dumpsites on the quality of groundwater and surface water. The water samples and leachates were collected from dumpsites in respective zones. The physicochemical properties of the samples were examined and determined in accordance with the standards of the American Public Health Association. Results indicated that the groundwater and surface water that are close to the dumpsites have an electrical conductivity of 385 and 245 Sd/cm, total dissolved solids of 168 and 128 mg/L, a turbidity of 4.6 and 22 NTU, a total alkalinity of 103 and 50 mg/L, a total hardness …

Effect Of Catholyte Concentration On Current Production During Chocolate Industry Wastewater Treatment By A Microbial Fuel Cell, Diana Rahayuning Wulan, Suprihanto Notodarmojo

Makara Journal of Technology

Microbial fuel cells (MFCs) use bacteria as a catalyst to oxidize organic and/or inorganic substrates and produce electric currents. Wastewater could function as an electron donor in the anode chamber and, thus, represents a very promising energy source. Catholytes, as electron acceptors, influence power production in MFCs by increasing the availability of electrons. The present research aims to determine the influence of catholyte concentration on current production in an aerobic two-chamber MFC. Aerobic treatment was carried out in the two-chamber MFC operated in an incubator at 37  1 °C with and without aeration in the cathode chamber. Wastewater from …

Evaluation Of Il-17a And Il-17f Gene Expression In Peripheral Blood Mononuclear Cells In Different Clinical Stages Of Chronic Hepatitis B Infection In An Iranian Population, Tannaz Akbari Kolagar, Seyed Reza Mohebbi, Fatemeh Ashrafi, Shahrzad Shoraka, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali

Makara Journal of Technology

Hepatitis B virus (HBV) infection is one of the main causes of liver damage, which can also lead to chronic hepatitis B (CHB) infection. More than 240 million individuals worldwide are chronic carriers of HBV. Among individuals with CHB who are untreated, approximately 15% – 40% will progress to liver cirrhosis or cancer. The interactions between HBV and host immune response play significant roles in the progression of CHB. CHB can be generally divided into four different clinical phases: immune tolerance (IT), immune clearance, inactive carrier, and Hepatitis B surface antigen (HBsAg)-negative reactivation phase (ENEG). Many studies showed that interleukins …

Laboratory Results And Mathematical Modeling Of Spore Surface Interactions In Stormwater Runoff, Anne M. Mikelonis, Katherine Ratliff, Sungmin Youn

All Engineering Faculty Research

Development of numerical models to predict stormwater-mediated transport of pathogenic spores in the environment depends on an understanding of adhesion forces that dictate detachment after rain events. Zeta potential values were measured in the laboratory for Bacillus globigii and Bacillus thuringiensis kurstaki, two common surrogates used to represent Bacillus anthracis, in synthetic baseline ultrapure water and laboratory prepared stormwater. Zeta potential curves were also determined for materials representative of urban infrastructure (concrete and asphalt). These data were used to predict the interaction energy between the spores and urban materials using Derjaguin-Landau-Verwey-Overbeek (DLVO) modeling. B. globigii and B. thuringiensis kurstaki …

We Need Fuzzy Techniques To Design Successful Human-Like Robots, Vladik Kreinovich, Olga Kosheleva, Laxman Bokati

Departmental Technical Reports (CS)

In this chapter, we argue that to make sure that human-like robots exhibit human-like behavior, we need to use fuzzy techniques -- and we also provide details of this usage. The chapter is intended both for researchers and practitioners who are very familiar with fuzzy techniques and also for researchers and practitioners who do not know these techniques -- but who are interested in designing human-like robots.

An Exercise Device Used To Achieve Bone Formation Metrics For The Strengthening Of The Proximal Femur., Sean P. Coyle

Electronic Theses and Dissertations

Lateral falls often lead to hip fracture particularly in the elderly who have low bone mineral density. These fractures frequently lead to indirect mortality soon after injury. Normal use over the course over a lifetime leads to optimized adaptation of the bone in the proximal femur according to normal loading. A lateral fall generates non-normal, lateral loading at the proximal hip where the bone has not adapted to withstand such loading. The resulting fracture is generated by reversed strains on the bone tissue in the femoral neck in the hip in contrast to vertical, quotidian loading. Modern practices for preventing …

Modeling The Effects Of Hyaluronic Acid Degradation On The Regulation Of Human Astrocyte Phenotype Using Multicomponent Interpenetrating Polymer Networks (Mipns), Andrea C. Jimenez-Vergara, Rachel Van Drunen, Tyler Cagle, Dany J. Munoz-Pinto

Engineering Faculty Research

Hyaluronic acid (HA) is a highly abundant component in the extracellular matrix (ECM) and a fundamental element to the architecture and the physiology of the central nervous system (CNS). Often, HA degradation occurs when an overreactive inflammatory response, derived from tissue trauma or neurodegenerative diseases such as Alzheimer’s, causes the ECM in the CNS to be remodeled. Herein, we studied the effects of HA content as a key regulator of human astrocyte (HAf) reactivity using multicomponent interpenetrating polymer networks (mIPNs) comprised of Collagen I, HA and poly(ethylene glycol) diacrylate. The selected platform facilities the modulation of HA levels independently of …

Black-Swan Type Catastrophes And Antifragility/Supra-Resilience Of Urban Socio-Technical Infrastructures, S. A, Timashev

Engineering Management & Systems Engineering Faculty Publications

This paper may be one of the first attempts dealing with the problem of creating, providing and maintaining antifragility of systems of interdependent urban critical infrastructures (CI) in the wake of black-swan type technological, ecological, economic or social catastrophes occurring in a municipality. A synonym is offered to describe antifragility from a positive psychology perspective, formulating the problem as the supraresilience problem. A brief description is given of the developed innovative approach for creating a supraresilient city/region using black-swan catastrophe and the antifragility concepts. Resilience metrics are formulated as well as methods of assessing damage, interdependence of infrastructures and convergent …

Modulation Of Ros In Nanosecond-Pulsed Plasma-Activated Media For Dosage-Dependent Cancer Cell Inactivation In Vitro, Chunqi Jiang, Esin Bengisu Sozer, Shutong Song, Nicola Lai, P. Thomas Vernier, Sigi Guo

Bioelectrics Publications

Dosage control of reactive oxygen and nitrogen species (RONS) is critical to low-temperature plasma applications in cancer therapy. Production of RONS by atmospheric pressure, nonequilibrium plasmas in contact with liquid may be modulated via plasma conditions including plasma treatment time and pulse voltage and repetition frequency. In this study, a terephthalic acid-based probe was used to measure hydroxyl radicals [OH_aq] in water exposed to plasma and to demonstrate that the OH_ag concentration increases linearly with treatment time. Fluorometric measurements of hydrogen peroxide concentration in plasma-activated water show a linear relationship between the H₂O₂ production …

Single-Particle Chemical Force Microscopy To Characterize Virus Surface Chemistry, Xue Mi, Caryn L. Heldt

Michigan Tech Publications, Part 1

Two important viral surface characteristics are the hydrophobicity and surface charge, which determine the viral colloidal behavior and mobility. Chemical force microscopy allows the detection of viral surface chemistry in liquid samples with small amounts of virus sample. This single-particle method requires the functionalization of an atomic force microscope (AFM) probe and covalent bonding of viruses to a surface. A hydrophobic methyl-modified AFM probe was used to study the viral surface hydrophobicity, and an AFM probe terminated with either negatively charged carboxyl acid or positively charged quaternary amine was used to study the viral surface charge. With an understanding of …