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Investigation Of Rate Pressure Product As A Metric To Quantify Cardiac Workload In Sleep Apnea Events, Carlos Cruz

Bioengineering Theses - Archive

An investigation on the use of rate pressure product (RPP) to measure the cardiac workload in sleep apnea patients is presented. RPP is the product of systolic blood pressure (SBP) and heart rate (HR). The application of RPP to quantify cardiac workload is combined with the detection of respiratory events occurring in close proximity (less than 30 seconds apart). These two combined factors provide a unique framework for analyzing sleep apnea events and are the primary novelty of the study. Close proximity events are referred to as respiratory event chains (RECs). Statistical analyses were conducted on various RPP metrics as …

The Effects Of Poloxamer 188 On Wound Closure In A Mouse Brain Endothelium Model, Mia Claire Grubbs

Bioengineering Theses - Archive

The blood-brain barrier (BBB) plays a crucial role in maintaining central nervous system homeostasis and, if structurally and functionally compromised, can lead to severe neurological consequences. This thesis explores the therapeutic potential of Poloxamer 188 (P188) in the context of BBB wound healing. P188, FDA-approved copolymer that is known for its cytoprotective properties, is examined for its impact on endothelial monolayers through in vitro scratch wound assays. The study aims to establish a consistent endothelial monolayer model, quantify wound healing dynamics, and assess the efficacy of P188 at varying concentrations. The thesis goals include detailed methodologies such as cell culture …

Comprehensive Analysis Of The Effects Of Superplasticizer Variation On The Workability And Strength Of Ready-Mix Concrete, Tahsin Tareque, Fahmid Tousif, Mirza Addaito Billah, Abdullah Al Masum Jabir, Seyedali Mirmotalebi

Civil Engineering Faculty Publications

This experimental study aims to examine the influence of many crucial parameters on the workability and compressive strength of Ready-Mix Concrete (RMC). The study utilized two distinct varieties of superplasticizers obtained from the local market. The fine aggregates utilized in this study were sourced from Sylhet sand, whereas the coarse aggregates were comprised of boulder crushed stone chips. The experimental procedures adhered to the requirements outlined by ASTM. A comprehensive investigation was conducted on a range of concrete compositions that used diverse chemical admixtures. The slump test was performed at regular intervals of 15 minutes until the slump value reached …

Hybrid Wall Outlet For Ac Or Dc Power Delivery, Garrett Knoller, Kerr Allan, Greg Perini

Electrical Engineering

The goal of this project is to develop hybrid DC and AC wall outlets for an efficient, flexible power interface. A DC plug standard is also proposed to allow DC devices to be safely powered by the outlet with the correct DC voltage for each device. The primary objective is to create a power outlet compatible with the proposed DC plug as well as NEMA 5-15 AC plugs, enabling the same outlet to power both types of load as needed. The outlet is intended for buildings and systems transitioning to an isolated DC grid to encourage DC development and adoption. …

Dc To Ac Inverter For A Microgrid-Inspired Power Distribution Architecture For Electric Vehicles, Bryan A. Carrillo Martinez, Eli Blacklock, Paul A. Samson, William S. Holt-Hillis

Electrical Engineering

This project builds upon the prototyping of a microgrid-inspired power distribution architecture for electric vehicles (EVs). The efficacy of this prototype aims to inform a full-scale power distribution system that charges an EV battery, supports the electric grid with important ancillary services, performs peer-to-peer EV charging, and works in conjunction with other AC and DC sources and loads. The scope of this report focuses specifically on the design, construction, and testing of the DC/AC inverter. Future development of this distribution architecture will incorporate synchronous generators, a battery management system, and an Arduino/Raspberry Pi-based communication system to fully simulate an electric …

Digital Filter Implementation On A Dsp Development Board, Tien Le, Helen Zhang

Electrical Engineering

This project to implement digital filters on a Digital Signal Processor (DSP) development board intends to demonstrate viability for future use in teaching digital signal processing lab courses. The digital filter types covered, including Finite Impulse Response (FIR) and Infinite Impulse Response (IIR) filters of various basic frequency responses, will mirror current DSP lab projects to fulfill course learning objectives for filter design and characterization. Design features will include speed optimization to enable real-time digital signal processing. This project will investigate the use of Code Composer Studio to compile C and assembly code to the DSP. Alternatives for currently available …

4-Band Personal Eq Device, Carson Kellerman

Electrical Engineering

The device is a 4-band EQ with 3.5mm audio input and output jacks. The device has 4 adjustable EQ bands. Each of the 4 bands are adjustable via knob potentiometers, and are able to boost or cut their respective center frequencies of 150Hz, 400Hz, 2500Hz, and 10kHz from -15dB to +15dB. The device is battery powered off of 1 9V battery and is able to function for 10 hours before needing to replace the batteries. The device has a Total Harmonic Distortion of less than 1% and a Signal to Noise Ratio greater than 60dB. Overall, this device allows music …

Novel Implementation Of Additive Manufacturing To Visualize The Human Brain Connectome, Greg Tyler

Computational and Data Sciences (MS) Theses

Additive manufacturing (AM) is an emerging technology with diverse areas of application. In this paper we explore a new application of AM that uses a subset of AM known as 3D printing, to create real life models of the human connectome. The human connectome is a color coded map of the connections in the human brain where directions are indicated by colors and the density of connections are indicated by color intensity.

There are several different algorithms for mapping the connections and describing the output. The Neu- roImaging Tools and Resource Collaboratory (NITRC) provides one such algorithm. It uses probabilistic …

Resilient, Sustainable, And Secure Systems Support For Ultra-Low-Power Computational Things, Nicole Tobias

All Dissertations

Wireless battery-free and energy-harvesting devices are expanding the reach and vision of the Internet of Things, where trillions of embedded computational things interconnect ubiquitously around us and inform many different aspects of our everyday lives. Designing these systems without batteries and interconnecting wires lowers maintenance, environmental, and economic costs while also extending device lifetime and deployment opportunities. Over the last decade, research on these ultra-low-power embedded sensors and systems has dramatically increased — enabling new and exciting prospects in many different scientific fields, from smart building and health monitoring applications to animal and activity tracking.

These systems are not without …

Cnc Retrofits, Fabian Samano, Murat Askin, Daniel Lonczak, Zane Campise

Mechanical Engineering

The Boxford CNC Lathe is a machine used for educational purposes. The goal of the CNC Retrofits project is to improve the Boxford MT2’s performance and functionality to enable Mr. Lonczak to manufacture customized ballpoint pens. Within this Final Design Review (FDR) document, we present design updates since the CDR and implementation/assembly techniques. This work culminates in a solution to Mr. Lonczak’s needs which is analyzed in three subsystems: main control, spindle position tracking, and user interface. Within this report, we show the results of each subsystem’s verification process. These results prove that the design concept was met by describing …

Classification Of Thorax Diseases From Chest X-Ray Images, Sharad Jayusukhbhai Dobariya

Electronic Theses, Projects, and Dissertations

Chest X-ray images are crucial for medical decisions and patient care. However, their manual interpretation is time-consuming and prone to human error. This project aims to create an automated system that uses deep learning techniques to classify thorax disease from chest X-ray images. We are using the NIH Chest X-Ray Dataset, which contains many annotated images, as input data for this project. This approach uses UNet architecture as its classification layer. UNet architecture is well-known for its efficiency in image segmentation. Adding residual blocks enhances this approach's ability to classify images. The goal of this project is to create a …

Condition Assessment Of Reinforced Concrete Sanitary Sewer Pipelines Using Probabilistic Methods And Advanced Inspection Tools, Moein Ebrahimi

Civil Engineering Dissertations - Archive

Large sanitary sewer pipelines (SSPs) are the backbone of modern infrastructure. They carry wastewater from smaller lines to treatment plans; therefore, they are critical for public health and safety. According to the ASCE report card published in 2021, the condition rate of sanitary sewage networks in the United States is D+ (i.e., poor) (ASCE 2021). Therefore, frequent inspections of SSPs are crucial for performing a proper life cycle management strategy. New inspection technologies such as LiDAR have recently been employed for rapid condition assessment of SSPs. Because of the precision of LiDAR inspection data, it can not only measure hydraulic …

A Numerical Modeling Analysis Of The San Francisco Bay And Sacramento-San Joaquin Delta: Riverine, Tidal, And Wind Processes, Drake A. Abrahamsson

Master's Theses

The primary motivation of this study is to analyze the 1D-2DH hydrodynamic model of the San Francisco Bay and Sacramento-San Joaquin Delta (SFBD) outlined in Nederhoff et al. (2021). I compared model water level data to 70 tidal records from the National Oceanic and Atmospheric Association (NOAA), the United States Geological Survey (USGS), the California Data Exchange Center (CDEC), and from local municipalities throughout the Bay Area to investigate how the model captures water levels and tidal constituent amplitudes. While the Nederhoff et al (2017) model analyzed an extended time period from 1950-2019, I analyzed M2 amplitude and tidal water …

Launch Vibration Attenuation For In-Space Assembly Cargo, Jered Bell

Master's Theses

This thesis investigates the implementation of a passive isolator with a pressurized air cushion for spacecraft payloads in mission architectures implementing in-space assembly technologies. A pressurized air bed capable of briefly surviving the space environment for cargo delivery was prototyped and experimentally evaluated for launch vehicle vibration dynamics resulting in a 72%, 93%, and 88% reduction in experienced GRMS loads for the X-Axis, Y-Axis, and Z-Axis, respectively. A preliminary Total Mass Loss evaluation of the Low-Density Polyethylene Film utilized for the air bed resulted in a mass loss of 0.7%, indicating that commercial off-the-shelf films might require minimal modification for …

Accelerated Testing Of Solder Spheres Under Combined Temperature, Current, And Shear Stresses To Estimate Reliability, Collin Ruby

Graduate Theses and Dissertations

With the densification of power electronics in the pursuit of decreased size and weight and increased efficiency, the need to investigate the properties of solder in packages with higher working temperatures and power densities is becoming apparent. Many research groups have conducted accelerated testing using methods such as thermal aging, shear or tensile stress tests, or electromigration tests, but relatively little research exists that considers the impact of several stresses in a combined study. This work aims to produce a novel method for estimating the lifetime of SAC305 solder joints under a combined stress scenario, which more accurately depicts the …

Motion Simulation And Risk Assessment Of Dropped Objects In Offshore Operations, Hanqi Yu

LSU New Orleans Theses and Dissertations

Subsea pipelines are a cost-effective and reliable way to transport hydrocarbons in offshore oil and gas development. However, dropped objects can pose hazards and cause damage to pipelines. This dissertation briefly introduces the hazards and hidden dangers caused by dropped containers, discusses motion simulation methods for different object shapes, and reviews risk assessment procedures for handling dropped objects in offshore operations. Ongoing research at the University of New Orleans' towing tank on dropped container models is also discussed. Using ANSYS Fluent, we simulate trajectories of container models and calculate relevant hydrodynamic coefficients for different dropped angles. We then apply risk …

Determining The Effects Of Glycocalyx Modifications On The Electrophysical Properties Of Human Mesenchymal Stem Cells, Rominna E. Valentine Ico

Electronic Theses, Projects, and Dissertations

Human mesenchymal stem cells (hMSCs) have gained popularity in clinical trials due to their multipotent differentiation characteristics, ability to secrete bioactive molecules, migrate into diseased or damaged tissues, and their immunosuppressive properties. HMSC cultures are heterogeneous, containing stem cells, partially differentiated progenitor cells, and fully differentiated cells. One of the major challenges with hMSCs therapeutic potential is the inability to select specific cell subpopulations due to an insufficient number of biomarkers. Often the biomarkers used, like those for fluorescence-activated cell sorting, are not sufficient to define hMSCs because they overlap with other cell types. Consequently, there is a need to …

Rabrs For Use In Biologically Enhanced Precipitation Of Struvite In Anaerobic Digester Effluent (Municipal Wastewater), Parker R. Goldsberry

All Graduate Theses and Dissertations, Fall 2023 to Present

Rotating Algae Biofilm Reactor (RABR) technology has been researched in studies over the past decade directed at nutrient management for water resource recovery facilities (WRRFs). This study investigated the growth of slow-release fertilizer crystals, referred to as struvite, in the algae biofilms of Rotating Algae Biofilm Reactors (RABRs) at the Central Valley Water Reclamation Facility, the largest water resource recovery facility in the State of Utah. RABRs used anaerobic digester (AD) filtrate as their nutrient source. AD effluent is high in nutrients like nitrogen and phosphorus. The levels of both phosphorus and nitrogen (in the form of ammonia) are regulated …

Student Reliance On Simulations: The Extent That Engineering Students Rely On The Outcomes Of Their Simulations, Jonathan Anderson

All Graduate Theses and Dissertations, Fall 2023 to Present

The purpose of this research was to investigate the factors that contributed to engineering education students’ reliance on technology while learning new concepts. The researcher hypothesized that students would give reliance to their technology, even in the face of evidence that the technology was not working as intended. This research used a mixed-methods approach to answer the research questions. Three questions guided the research: (1) How are the participant’s level of automation complacency and the correctness of the simulation that participant is using related?; (2) How is automation bias related to a participant’s ability to recognize errors in a simulation?; …

Co2 Storage Capacity And Injectivity Of Stacked Carbonates Of The Pennsylvanian And Permian In Western Nebraska, Lateef Lawal

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Geological carbon storage (GCS) is a critical aspect of carbon capture and storage (CCS) in which captured CO₂ from power plants and industrial processes is injected and stored securely underground. Potential subsurface rock formations include saline aquifers, depleted oil and gas reservoirs, unmineable coal seams and volcanic rocks. GCS technology has been proven in the United States and many other parts of the world as a net-zero carbon emission strategy to mitigate the current climate crisis of our planet. Unlike other states such as Wyoming, GCS projects are still in the early phases in Nebraska. The goal of this …

1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (Mptp)-Treated Adult Zebrafish As A Model For Parkinson’S Disease, Emmeline Bagwell

All Theses

The use of adult zebrafish, Danio rerio, as a model for human neurodegenerative diseases has proven valuable in pharmaceutical development and genetic disease research due to their high genetic homology to humans, cost-effective husbandry, and quick life cycle breeding times. Despite their promise, most zebrafish research has focused on embryonic stage organisms, primarily due to the ease of direct handling protocols and rapid progression through developmental stages. Recognizing the limitations of early-stage organisms in modeling adult diseases, recent efforts have shifted the applicability of zebrafish models, particularly for Parkinson's Disease, due to the nature of the disease impacting patients 55 …

Radiation Exposure Calibration Of The Al2o3:C With Radium-226 And Cesium-137 Using The Osl Method, Selma Tepeli Aydin

All Theses

Optically stimulated luminescence (OSL) dosimetry was utilized to calibrate Al₂O₃:C powder dosimeters, available commercially as the nanoDot® from Landauer Inc., and compare the dosimeter response to radium-226 (²²⁶Ra) and cesium-137 (¹³⁷Cs). The signal from the OSL was quantified using a microSTARii^® OSL reader also produced by Landauer Inc. Dose-response curves were developed for ²²⁶Ra and ¹³⁷Cs experiments (5 dosimeters each) at thirteen absorbed doses. Individual dosimeter response was tracked by serial number. Linear regression analysis was performed to determine if there were significant differences between the intercepts of the …

Evaluation Of The Long-Term Performance Of Ogfc In South Carolina, Rishiraj Brahmbhatt

All Theses

Since the 1970s, South Carolina has employed open graded friction courses (OGFC) on high-speed asphalt roadways to enhance wet weather safety. While these mixes have indeed enhanced safety, they still grapple with durability issues, particularly concerning raveling. This research aimed to assess the prolonged performance of OGFC pavements in South Carolina, with a specific emphasis on isolated raveling occurrences. In 2012, the South Carolina Department of Transportation (SCDOT), constructed the first Warm Mix OGFC test section in South Carolina on I-20 Eastbound in Kershaw County, spanning 3.9 miles, using the Evotherm additive and excluding fibers. Following the success of this …

Barriers To Integrating Magnetic Resonance Imaging Systems In Emergency Medical Service Ambulances For Stroke Care, Arvind Kolangarakath

All Theses

Stroke is a life-threatening condition that can cause permanent damage by stopping blood flow in the brain. Quick and precise intervention is imperative, as every second lost increases tissue deterioration and impacts patient outcomes. Several technological advancements such as Magnetic Resonance Imaging (MRI), have revolutionized stroke care by enabling more accurate and quicker diagnoses in hospitals. Portable head MRI scanners with lower magnetic fields are a recent innovation capable of providing neuroimaging at the point of care within hospital settings. Integrating such a device into ambulances could potentially enhance stroke care during transit, facilitating prompt diagnosis and prognosis. However, few …

Custom-Designed And Collaborative Unmanned Systems With Learning-Based Applications, Robert Zanone

All Theses

This paper presents a culmination of work utilizing custom-designed autonomous vehicles and learning based simulations applied to real world applications across three distinct research domains. The first focuses on deploying autonomous drones in an agricultural setting for plant phenotyping. A telescoping arm is used to deploy a camera into the plant foilage for under-the-canopy imaging. The system utilizes on-board image processing to identify early-stage issues such as diseases, bacteria, and pests in crop plants to provide data for crop loss mitigation. The system takes advantage of the maneuverability of drones allowing for quick random sampling when traversing large areas.

In …

Medical Simulation-Based Sensor Methods For Ultrasound-Guided Dialysis Cannulation Skill Assessment, Devansh Shukla

All Theses

End-stage kidney disease (EKSD) is the final, permanent stage of chronic kidney disease (CKD), where the body's kidneys cannot filter blood sufficiently. Hemodialysis treats ESKD by filtering wastes and water from your blood externally via a dialyzer. Patients on hemodialysis require a vascular access, typically an arteriovenous fistula (AVF) or arteriovenous graft (AVG) for dialysis, which is used three times a week for about four hours a session. These life-saving therapies can be quite tedious, especially for elderly patients and patients with co-morbidities. As such, successful cannulation is extremely important to ensure the longevity of the patient's vascular access and …

Assessing The Effectiveness Of Nuclear Security Training And Education In Ghana, Michael Nii Sanka Ansah, Boris Stepanov Pavlovich, Paul Atta Amoah, David Okoh Kpeglo, Simon Adu, Bright Kwame Afornu

International Journal of Nuclear Security

Growing attention is being given to nuclear power across several African countries, including in Ghana. The world is depending on nuclear energy as a reliable and efficient means of energy generation. Ghana as a country is developing nuclear energy; thus, equal attention must be directed toward nuclear safety and security. Ghana is gradually developing interest in and is devoting substantial required resources to educating and training on nuclear security to meet the standards required by international bodies. Institutions such as the Nuclear Safety and Security Centre and the School of Nuclear and Allied Sciences of the Ghana Atomic Energy Commission …

A Wearable Fluorescence Imaging Device For Intraoperative Identification Of Human Brain Tumors, Mehrana Mohtasebi, Chong Huang, Mingjun Zhao, Siavash Mazdeyasna, Xuhui Liu, Samaneh Rabienia Haratbar, Faraneh Fathi, Jinghong Sun, Thomas A. Pittman, Guoqiang Yu

Biomedical Engineering Faculty Publications

Malignant glioma (MG) is the most common type of primary malignant brain tumors. Surgical resection of MG remains the cornerstone of therapy and the extent of resection correlates with patient survival. A limiting factor for resection, however, is the difficulty in differentiating the tumor from normal tissue during surgery. Fluorescence imaging is an emerging technique for real-time intraoperative visualization of MGs and their boundaries. However, most clinical grade neurosurgical operative microscopes with fluorescence imaging ability are hampered by low adoption rates due to high cost, limited portability, limited operation flexibility, and lack of skilled professionals with technical knowledge. To overcome …

Development Of A Machine Learning System For Irrigation Decision Support With Disparate Data Streams, Eric Wilkening

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

In recent years, advancements in irrigation technologies have led to increased efficiency in irrigation applications, encompassing the adoption of practices that utilize data-driven irrigation scheduling and leveraging variable rate irrigation (VRI). These technological improvements have the potential to reduce water withdrawals and diversions from both groundwater and surface water sources. However, it is vital to recognize that improved application efficiency does not necessarily equate to increased water availability for future or downstream use. This is particularly crucial in the context of consumptive water use, which refers to water consumed and not returned to the local or sub-regional watershed, representing a …

Risk Assessment Of Reinforced Concrete Sewer Pipes Under External Loading And Adverse Environmental Conditions Using An Adaptive Neuro-Fuzzy System, Khaled Saleh Khaled Abuhishmeh

Civil Engineering Dissertations - Archive

Failure of sewer mains poses a significant threat to the society, necessitating a robust risk assessment tool that integrates failure likelihood and associated consequences for effective prioritization of mitigation efforts. This dissertation addresses this need through three key objectives: 1. Failure Likelihood Assessment: The study utilizes Monte-Carlo simulation to evaluate the probability of sewer main failures in common agressive environments, considering factors like sulfide and chloride exposures. It highlights that chloride-induced cracks and bond strength loss are more critical than sulfide-induced wall thickness loss. The degradation of concrete and reinforcement properties under chloride attack significantly reduces ductility, emphasizing the importance …