Digital Commons Network^™

Recent Progress In Microrna Detection Using Integrated Electric Fields And Optical Detection Methods, Logeeshan Velmanickam, Dharmakeerthi Nawarathna

Electrical & Computer Engineering Faculty Publications

Low-cost, highly-sensitivity, and minimally invasive tests for the detection and monitoring of life-threatening diseases and disorders can reduce the worldwide disease burden. Despite a number of interdisciplinary research efforts, there are still challenges remaining to be addressed, so clinically significant amounts of relevant biomarkers in body fluids can be detected with low assay cost, high sensitivity, and speed at point-of-care settings. Although the conventional proteomic technologies have shown promise, their ability to detect all levels of disease progression from early to advanced stages is limited to a limited number of diseases. One potential avenue for early diagnosis is microRNA (miRNA). …

Estimation Of Differential Pathlength Factor From Nirs Measurement In Skeletal Muscle, B. Koirala, A. Concas, A. Cincotti, Yi Sun, A. Hernández, M. L. Goodwin, L. B. Gladden, N. Lai

Electrical & Computer Engineering Faculty Publications

The utilization of continuous wave (CW) near-infrared spectroscopy (NIRS) device to measure non-invasively muscle oxygenation in healthy and disease states is limited by the uncertainties related to the differential path length factor (DPF). DPF value is required to quantify oxygenated and deoxygenated heme groups' concentration changes from measurement of optical densities by NIRS. An integrated approach that combines animal and computational models of oxygen transport and utilization was used to estimate the DPF value in situ. The canine model of muscle oxidative metabolism allowed measurement of both venous oxygen content and tissue oxygenation by CW NIRS under different oxygen delivery …

Adversarial Training Based Domain Adaptation Of Skin Cancer Images, Syed Qasim Gilani, Muhammad Umair, Maryam Naqvi, Oge Marques, Hee-Cheol Kim

Electrical & Computer Engineering Faculty Publications

Skin lesion datasets used in the research are highly imbalanced; Generative Adversarial Networks can generate synthetic skin lesion images to solve the class imbalance problem, but it can result in bias and domain shift. Domain shifts in skin lesion datasets can also occur if different instruments or imaging resolutions are used to capture skin lesion images. The deep learning models may not perform well in the presence of bias and domain shift in skin lesion datasets. This work presents a domain adaptation algorithm-based methodology for mitigating the effects of domain shift and bias in skin lesion datasets. Six experiments were …

Accelerating Cavity Fault Prediction Using Deep Learning At Jefferson Laboratory, Md M. Rahman, A. Carpenter, K. Iftekharuddin, C. Tennant

Electrical & Computer Engineering Faculty Publications

Accelerating cavities are an integral part of the continuous electron beam accelerator facility (CEBAF) at Jefferson Laboratory. When any of the over 400 cavities in CEBAF experiences a fault, it disrupts beam delivery to experimental user halls. In this study, we propose the use of a deep learning model to predict slowly developing cavity faults. By utilizing pre-fault signals, we train a long short-term memory-convolutional neural network binary classifier to distinguish between radio-frequency (RF) signals during normal operation and RF signals indicative of impending faults. We optimize the model by adjusting the fault confidence threshold and implementing a multiple consecutive …

A Review Of Emerging Sensor Technologies For Tank Inspection: A Focus On Lidar And Hyperspectral Imaging And Their Automation And Deployment, Sergio Pallas Enguita, Chung-Hao Chen, Samuel Kovacic

Electrical & Computer Engineering Faculty Publications

This paper reviews various sensor technologies for tank inspection, focusing on Light Detection and Ranging (LiDAR) and Hyperspectral Imaging (HSI) as advanced solutions for corrosion detection. These technologies are evaluated alongside traditional methods such as ultrasonic, electromagnetic, and thermographic inspections. This review highlights their potential to enhance inspection accuracy, reduce the limitations of manual inspection, and support integrated data analysis for comprehensive asset management. Additionally, this paper proposes a pathway for automating these techniques to streamline inspection processes and improve implementation in practical applications.

An Overview Of The Relationships Between The Food Industry And Nanotechnology, Mehdi Koushki, Nasrin Amiri-Dashatan, Hossein Pourghadamyari, Hadi Khodabandehloo, Fatemeh Bagheri, Masoumeh Farahani, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Background and Objective: Due to the growth of the global population, food demands are increasing. Hence, the need to develop more efficient methods for producing better quality, safer, and more sustainable food seems essential. In the past decades, the use of nanoscale materials has increased greatly due to the unique chemical, physical, and biological characteristics of nanomaterials compared to bulk materials. This research presents nanotechnology role in improving sensorial properties (taste, appearance, and texture) and safety aspects as well as processing and packaging of foods. The use of nano-omics-based technologies and artificial intelligence-nanotechnology-based technologies in the food industry is also …

Predictive Modeling Of Healthcare Traffic Using Machine Learning: A Comparative Study, Shadman Mahmood Khan Pathan, Sakan Binte Imran, M. M. Shabab Iqbal, Muhammad Enayetur Rahman, Md Nurul Absar Siddiky, Muhammad Rezaur Rahman, Md. Rafid Hassan, Nondon Lal Dey, Md. Sobuj Hossain

Electrical & Computer Engineering Faculty Publications

Effective healthcare traffic management is critical for ensuring prompt medical services, particularly in emergencies where delays can have life-threatening consequences. This study conducts a comparative analysis of three popular machine learning models—Linear Regression, Decision Trees, and Random Forests—for predicting healthcare-related traffic volumes. Utilizing a comprehensive dataset from a metropolitan interstate traffic system, the models were evaluated based on key performance metrics, including Mean Squared Error (MSE), R² Score, and execution time. The findings demonstrate that the Random Forest model outperforms the others, offering superior predictive accuracy and efficiency. These insights are valuable for optimizing traffic management in healthcare, ultimately contributing …

Distance Estimation Based On Step Frequency Using Accelerometer Data, Rami M. Al-Naimat, Khawlah M. Harahsheh, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

In recent years, smartphone sensors have become one of the most important and easily available sensors to facilitate people's lives, especially in health care and positioning (indoor environments). However, the data coming from smartphone sensors can be distorted during the user’s movement such as irrelevant movements, walk mode, and speed of walking. This distortion (noise) impairs the estimated distance accuracy (accumulative error) which increases with increasing walking distance. In addition, the accuracy of the distance traveled is affected by the user's speed, as the speed affects the step length. This work proposes a novel approach for calculating step length in …

Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Romel Robinson Ii

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

A Resilient Decarbonization Package For The Hoopa Shopping Center, Esther Obikoya

Cal Poly Humboldt theses and projects

The Hoopa Shopping Center, located within the Hoopa Valley Tribe Reservation, faces significant energy cost fluctuations and reliability issues. Given the susceptibility of remote communities to power disruptions, the Tribe's move toward achieving a sustainable and resilient power infrastructure is essential. This study investigates the technical and economic decarbonization strategies for the Hoopa Shopping Center, focusing on reducing energy bills, energy consumption, and greenhouse gas emissions through electrification and energy efficiency improvements, as well as the integration of renewable energy sources.

This decarbonization could be done in a way consistent with the development of a microgrid to energize the community …

Mouralherwaqh: Coastal Wetland Road Crossing Da’Luk, Filip Amborski

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

Neurosymbolic Value-Inspired Ai (Why, What, And How), Amit Sheth, Kaushik Roy

Publications

The rapid progression of Artificial Intelligence (AI) systems, facilitated by the advent of Large Language Models (LLMs), has resulted in their widespread application to provide human assistance across diverse industries. This trend has sparked significant discourse centered around the ever-increasing need for LLM-based AI systems to function among humans as part of human society, sharing human values, especially as these systems are deployed in high-stakes settings (e.g., healthcare, autonomous driving, etc.). Towards this end, neurosymbolic AI systems are attractive due to their potential to enable easy-tounderstand and interpretable interfaces for facilitating valuebased decision-making, by leveraging explicit representations of shared values. …

K-Perm: Personalized Response Generation Using Dynamic Knowledge Retrieval And Persona-Adaptive Queries, Kanak Raj, Kaushik Roy, Vamshi Bonagiri, Priyanshul Govil, Krishnaprasad Thirunarayan, Raxit Goswami, Manas Gaur

Publications

Personalizing conversational agents can enhance the quality of conversations and increase user engagement. However, they often lack external knowledge to tend to a user’s persona appropriately. This is particularly crucial for practical applications like mental health support, nutrition planning, culturally sensitive conversations, or reducing toxic behavior in conversational agents. To enhance the relevance and comprehensiveness of personalized responses, we propose using a two-step approach that involves (1) selectively integrating user personas and (2) contextualizing the response with supplementing information from a background knowledge source. We develop K-PERM (Knowledge-guided PErsonalization with Reward Modulation), a dynamic conversational agent that combines these elements. …

Causal Event Graph-Guided Language-Based Spatiotemporal Question Answering, Kaushik Roy, Alessandro Oltramari, Yuxin Zi, Chathurangi Shyalika, Vignesh Narayanan, Amit Sheth

Publications

Large Language Models have excelled at encoding and leveraging language patterns in large text-based corpora for various tasks, including spatiotemporal event-based question answering (QA). However, due to encoding a text-based projection of the world, they have also been shown to lack a fullbodied understanding of such events, e.g., a sense of intuitive physics, and cause-and-effect relationships among events. In this work, we propose using causal event graphs (CEGs) to enhance language understanding of spatiotemporal events in language models, using a novel approach that also provides proofs for the model’s capture of the CEGs. A CEG consists of events denoted by …

Exploring Alternative Approaches To Language Modeling For Learning From Data And Knowledge, Yuxin Zi, Kaushik Roy, Vignesh Narayanan, Amit Sheth

Publications

Despite their wide applications to language understanding tasks, large language models (LLMs) still face challenges such as hallucinations - the occasional fabrication of information, and alignment issues - the lack of associations with human-curated world models (e.g., intuitive physics or common-sense knowledge). Additionally, the black-box nature of LLMs makes it highly challenging to train them meaningfully in order to achieve a desired behavior. Specifically, the attempt to adjust LLMs’ concept embedding spaces can be highly intractable, which involves analyzing the implicit impact on LLMs’ numerous parameters and the resulting inductive biases. This paper proposes a novel architecture that wraps powerful …

Tutorial: Knowledge-Infused Artificial Intelligence For Mental Healthcare, Kaushik Roy

Publications

Artificial Intelligence (AI) systems for mental healthcare (MHCare) have been ever-growing after realizing the importance of early interventions for patients with chronic mental health (MH) conditions. Social media (SocMedia) emerged as the go-to platform for supporting patients seeking MHCare. The creation of peer-support groups without social stigma has resulted in patients transitioning from clinical settings to SocMedia supported interactions for quick help. Researchers started exploring SocMedia content in search of cues that showcase correlation or causation between different MH conditions to design better interventional strategies. User-level Classification-based AI systems were designed to leverage diverse SocMedia data from various MH conditions, …

Ai Trustworthy: Ethical Challenges And Strategies, Jian Liu, Iwan Sandjaja, Donald C. Wunsch

Electrical and Computer Engineering Faculty Research & Creative Works

This paper explores the pivotal role of trust in the widespread application of Artificial Intelligence (AI) across various domains. We review AI applications in sectors like energy, healthcare, and autonomous vehicles and discuss the crisis of human trust they face. This paper introduces a novel framework that delineates the relationship between AI transparency and user trust, highlighting specific industry applications. Through a systematic review of recent literature, we first delve into factors such as emotional response, acceptance, transparency, accuracy, and interpretability that shape human trust in AI. We then underscore the necessity of ethical AI practices and highlight the importance …

Designing High-Performance Identity-Based Quantum Signature Protocol With Strong Security, Sunil Prajapat, Pankaj Kumar, Sandeep Kumar, Ashok Kumar Das, Sachin Shetty, M. Shamim Hossain

VMASC Publications

Due to the rapid advancement of quantum computers, there has been a furious race for quantum technologies in academia and industry. Quantum cryptography is an important tool for achieving security services during quantum communication. Designated verifier signature, a variant of quantum cryptography, is very useful in applications like the Internet of Things (IoT) and auctions. An identity-based quantum-designated verifier signature (QDVS) scheme is suggested in this work. Our protocol features security attributes like eavesdropping, non-repudiation, designated verification, and hiding sources attacks. Additionally, it is protected from attacks on forgery, inter-resending, and impersonation. The proposed scheme benefits from the traditional designated …

Embedding Software Engineering In Mixed Methods: Computationally Enhanced Risk Communication, Ann Marie Reinhold, Madison H. Munro, Elizabeth A. Shanahan, Ross J. Gore, Barry C. Ezell, Clemente I. Izurieta

VMASC Publications

Mixed methods research ameliorates many convergent research challenges within the contemporary sociotechnical landscape. We suggest the integration of software engineering in mixed methods studies is a critical step to address some of the remaining and persistent challenges. One such research challenge where software engineering is particularly well suited is in hazard preparedness—in particular, the creation of risk communication messages to mitigate or prevent harm. Computationally enhanced risk communication is convergent research that integrates software engineering and social science research for the benefit of protecting humans and infrastructure. To this end, we developed a mixed methods framework for the efficient construction …

Development Of Digital Twin For Fdm Printer With Preventive Cyber-Attack And Control Algorithms, Md Hazrat Ali, Asad Malik, Nursultan Jyeniskhan, Muhammad Arif Mahmood, Essam Shehab, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

This paper presents a developed model of a Digital Twin (DT) for a fused deposition modeling (FDM) printer, real-time defect detection, and proposed frameworks for preventing cyber-attacks in real-time. It also highlights a model predictive control (MPC) algorithm for controlling the material feed based on a real-time feedback system. The system is designed and developed based on DT, and MPC with integrated machine learning (ML) algorithms to establish real-time process control and enhance the safety and reliability of the physical plant. ML algorithm is used for anomaly detection based on the convolutional neural network (CNN) model. The developed system can …

Valorization Of Spent Vetiver Roots For Biochar Generation, Sameer Neve, Dibyendu Sarkar, Manas Warke, Teresa Bandosz, Rupali Datta

Michigan Tech Publications

Vetiver root is widely used to produce essential oils in the aromatherapy industry. After the extraction of oil, the roots are disposed of as waste. The central objective of this research was to explore the conversion of this waste into a resource using a circular economy framework. To generate biochar, vetiver roots were pyrolyzed at different temperatures (300, 500, and 700 °C) and residence times (30, 60, and 120 min). Analysis showed the root biochar generated at 500 °C and held for 60 min had the highest surface area of 308.15 m2/g and a yield of 53.76%, in addition to …

Quantifying The Impact Of A Constructed Wetland On Downstream Nitrate Concentrations And Loads In The U.S. Midwest, Elliot Anderson, Keith E. Schilling, Craig L. Just, Bong Chul Seo

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Constructed wetlands are standard conservation practices used to reduce nitrate loads in agricultural watersheds. Many studies have examined the efficiency of denitrification in wetlands under various scenarios, but quantifying the watershed-scale impact of wetlands on downstream nitrate levels is rarely done using field observations. In this study, we estimated nitrate removal in a constructed wetland in the headwaters of Mud Creek, a HUC12 watershed in eastern Iowa, from May–September 2022 and May–September 2023 (a ten-month period). We also measured nitrate loads at four successive downstream sites, three along Mud Creek and one below its confluence with the larger Cedar River. …

Personalized Bayesian Inference For Explainable Healthcare Management And Intervention, Utkarshani Jaimini, Krishnaprasad Thirunaravan, Maninder Kalra, Robin Dawson, Amit Sheth

Publications

Chronic healthcare conditions such as Asthma re- quires constant monitoring and managing of symptoms and their triggers for better quality of life. Each asthma patient reacts very differently to potential triggers. Hence, there is a need to develop a explainable personalized framework for each patient to capture susceptibility to asthma triggers. We developed a personalized knowledge-based probabilistic model to predict asthma exacerbation for different environmental factors utilizing patient generated health data from pediatric asthma patients. Further, the personalized model provides a metric, called Health Coefficient, to quantify the health of a patient for varying environmental factors. We demonstrate the predictive …

Proknow: Process Knowledge For Safety Constrained And Explainable Question Generation For Mental Health Diagnostic Assistance In The Age Of Large Language Models, Kaushik Roy, Manas Gaur, Misagh Soltani, Vipula Rawte, Ashwin Allen, Amit P. Sheth

Publications

Current Virtual Mental Health Assistants (VMHAs) primarily offer counseling and suggestive care but do not assist with patient diagnosis due to their lack of training in safety-constrained and specialized clinical process knowledge, referred to as ProKnow. In this work, we define ProKnow as an ordered set of information aligned with evidence-based guidelines or categories of conceptual understanding used by domain experts. We also introduce a new dataset of diagnostic conversations guided by safety constraints and Pro- Know, known as ProKnow-data. We develop a method for natural language question generation (NLG) designed to interactively gather diagnostic information from patients, termed ProKnow-algo. …

Salmonella Detection In Food Using A Hek-Htlr5 Reported Cell-Based Sensor, Esma Eser, Victoria A. Felton, Rishi Drolia, Arun K. Bhunia

Biological Sciences Faculty Publications

The development of a rapid, sensitive, specific method for detecting foodborne pathogens is paramount for supplying safe food to enhance public health safety. Despite the significant improvement in pathogen detection methods, key issues are still associated with rapid methods, such as distinguishing living cells from dead, the pathogenic potential or health risk of the analyte at the time of consumption, the detection limit, and the sample-to-result. Mammalian cell-based assays analyze pathogens’ interaction with host cells and are responsive only to live pathogens or active toxins. In this study, a human embryonic kidney (HEK293) cell line expressing Toll-Like Receptor 5 (TLR-5) …

Receptor-Targeted Next-Generation Probiotics Ameliorate Mammalian Colitis, Nicholas L. F. Gallina, Vignesh Nathan, Akshay Krishnakumar, Dongqi Liu, Rishi Drolia, Nicole Irrizary Tardi, Yang Fu, Manalee Samadar, Shivendra Tenguria, Alvin Cai, Ruth Eunice Centeno-Martinez, Timothy A. Johnson, Abigail Cox, Lavanya Reddivari, Bruce Applegate, Xingjian Bai, Luping Xu, Deepti Tanjore, Ramesh Vemulapalli, Rahim Rahimi, Arun K. Bhunia

Biological Sciences Faculty Publications

Introduction: a loss of intestinal barrier function, inflammation, and an elevated expression of epithelial heat shock protein 60 (Hsp60) are features of an inflamed bowel. Probiotics have been used to alleviate colitis-induced pathologies, but offer poor adhesion and adaptation to the diseased gut. We hypothesize that enhancing probiotic adhesion in the inflamed bowel may ameliorate such pathologies. Listeria adhesion protein (LAP; 94-kDa acetaldehyde alcohol dehydrogenase) aids Listeria attachment to the epithelial cells by interacting with the mammalian receptor Hsp60. Bioengineered Lactobacillus casei probiotics (BLPs) expressing LAP showed strong interaction with epithelial Hsp60, a high immunomodulatory response, and sustained epithelial barrier …

Ai And Ml-Based Risk Assessment Of Chemicals: Predicting Carcinogenic Risk From Chemical-Induced Genomic Instability, Ajay Vikram Singh, Preeti Bhardwaj, Peter Laux, Prachi Pradeep, Madleen Busse, Andreas Luch, Akihiko Hirose, Christopher J. Osgood, Michael W. Stacey

Biological Sciences Faculty Publications

Chemical risk assessment plays a pivotal role in safeguarding public health and environmental safety by evaluating the potential hazards and risks associated with chemical exposures. In recent years, the convergence of artificial intelligence (AI), machine learning (ML), and omics technologies has revolutionized the field of chemical risk assessment, offering new insights into toxicity mechanisms, predictive modeling, and risk management strategies. This perspective review explores the synergistic potential of AI/ML and omics in deciphering clastogen-induced genomic instability for carcinogenic risk prediction. We provide an overview of key findings, challenges, and opportunities in integrating AI/ML and omics technologies for chemical risk assessment, …

Scshm Benchmark Study On Bridge In-Service Structural Monitoring, Maria Pina Limongelli, Doug Thomson, Sreenivas Alampalli, Aftab Mufti, Thomas Schumacher, Luca Martinelli, Othmane Lasri, Harry Shenton, Genda Chen, Mohammad Noori, Farnaz Raeisi, Ahmed Silik, Ji Dang, Ray Hoemsen

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The mission of the Society of Civil Structural Health Monitoring (SCSHM, previously known as ISHMII) is to advance the understanding and application of structural monitoring methodologies for the management of civil infrastructure systems. To enable comparative and contrasting studies of various monitoring issues and technologies, the SCSHM Committee on Data-Enhanced Infrastructures Management (DEIMC) identified the need for benchmark problems in the areas of bridge and building structural monitoring. This article reports and briefly discusses the first benchmark study on in-service structural monitoring of bridges that was developed in collaboration with the University of Manitoba, and presents the structure details, study …

Studying Contribution Of Associated Stakeholders In Risk Control Of Modularized Construction Under Different Project Delivery Methods: A Graph-Restricted Cooperative Games Approach, Mohamad Abdul Nabi, Islam H. El-Adaway

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Modularization is associated with various project benefits including cost savings, schedule reduction, improved quality, among others. However, successful implementation of modular projects requires early collaboration and proactive management of various associated risks. Both project communication structures and early engagement of all project stakeholders have a great impact on risk mitigation efficiency in modular construction. The goal of this paper is to study the stakeholders' contribution in risk control of modular construction projects under different delivery methods. To this end, the authors followed a multistep methodology including (1) literature analysis to assign 17 modular risks among the various project stakeholders; (2) …

System Dynamics Modeling For Investigating The Retention Of Skilled Labor In The Construction Market, Tamima Elbashbishy, Islam H. El-Adaway

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Limited skilled labor has been one of the greatest challenges facing the construction industry, especially after COVID. In 2019, around 80% of contractors in the US reported problems in hiring enough skilled workers. Labor retention has been one of the major contributors to skilled labor shortages in construction. The goal of this paper is to study the impact of key construction industry characteristics and economic conditions on skilled labor shortages. This goal is achieved by simulating the flow of skilled workers throughout the construction industry. To this end, a system dynamics (SD) model was developed to represent skilled labor and …