Digital Commons Network^™

Biomechanical Effects Of Worn-Out Shoe Outsoles And Insoles On The Human Foot, Yuka M. Iwashita, James A. Engebretson, Shreeshan Jena

College of Engineering Summer Undergraduate Research Program

The combination of outsole, midsole and insole layers of new shoes provide proper cushioning to the foot during the daily activities of life. Subsequently, the wear-based degeneration or damage to one or more of these sole layers can reduce the cushioning effect to the plantar surface of the foot. This reduction of cushioning effect can impact the distribution of stress concentration regions along the foot plantar surfaces and lead to foot pathologies. The present proposed research intends to study these effects of shoe-wear on the plantar surface of the human foot, using FEA (ABAQUS) and experimental methods. Commonly, the worn-out …

Understanding And Enhancing Sustainability Literacy In Cal Poly's College Of Engineering, Kenna Toohill

College of Engineering Summer Undergraduate Research Program

This study uses survey data collected from Cal Poly students to analyze engineering students' sustainability knowledge and their perspectives on Cal Poly's efficacy in teaching concepts in sustainability. It also compares the College of Engineering to other colleges to determine if, and how, CENG is behind in environmental education at Cal Poly.

Significance Of Noninvasive Endothelial Dysfunction And Other Cardiovascular Measurements In Various Communities, Sofi Z. David, Lily Wilcox, Kalia Richard

College of Engineering Summer Undergraduate Research Program

This pilot study aims to raise awareness of endothelial dysfunction in underrepresented communities, where cardiovascular disease is prevalent. By delivering educational presentations and materials, the study seeks to increase participants' understanding and interest in endothelial dysfunction, potentially leading to proactive health behaviors. The results will inform future initiatives to enhance public knowledge and reduce the burden of cardiovascular disease in these communities.

In the future, there will also be a 3 vs 5-minute hyperemia study. Thirty participants without a history of cardiovascular disease will undergo testing using the Cordex SmartCuff™ device. If the three-minute hold proves to accurately measure endothelial …

Machine Learning-Based Stress Detection Using Smartphones And Wearable Sensors, Robert Burns, Kassandra Martinez-Mejia

College of Engineering Summer Undergraduate Research Program

Stress and mental health have been considered increasing global concerns in modern society, including some of the illnesses responsible for a large proportion of comorbidities and deaths worldwide, such as depression and cardiovascular disease. Recently, smartphones, smartwatches, and smart wristbands have become an integral part of our lives and have reached widespread usage [1]. This raised the question of whether we can detect and prevent stress with smartphones and wearable sensors wirelessly. The challenge of such an approach is that the weak ECG signal is prone to errors, and the battery life of the smart devices is limited. In this …

Importance Sampling To Learn Vasopressor Dosage To Optimize Patient Mortality In An Interpretable Manner, Anshul Rastogi

Holster Scholar Projects

Sepsis is a life-threatening organ dysfunction resulting from an improperly compensated bodily response to infection. There is a high urgency among clinicians to develop a set of real-time explainable treatment guidelines and tools to address the high mortality rate of sepsis patients. We present a reinforcement learning approach for vasopressor drug dosage in intensive care unit sepsis patients to achieve a better-than-expert treatment policy. We preserved interpretability with a prototype learning layer and learn actions in an off-policy manner with importance sampling. We evaluated our design on the MIMIC-IV deidentified electronic health record dataset with an 80%-20% training-validation split for …

Assessing Safety Culture: Lessons From The Aviation Industry, Mirrette Gendi, Cheri L. Marcham, Michael O'Toole

Publications

SAFETY CULTURE has been a topic of debate in academia as much as it has been in the practice of various industries (Zohar, 2010). Although the concept and definition of safety culture and what it entails have consumed much of the debate, the assessment of safety culture has been the most controversial. Yet, on the academic level, the topic of monitoring and measuring safety culture has seen limited research that offers reliable and valid assessment tools (Goodheart & Smith, 2014), especially when compared to the importance of safety culture as a component of a safety management system (SMS).

Assessing The Impact Of Femur Morphological Variations On Pediatric Hip Joint Biomechanics Using Statistical Shape Modeling, Tamara Chambers

Doctoral Dissertations and Master's Theses

This dissertation aimed to (1) quantify morphological variations in the pediatric hip joint and (2) evaluate the sensitivity of an infant musculoskeletal model (MSM) to these variations, considering hip joint center estimation errors. A shape statistical model (SSM) of decedent infant femurs from the Ortolani collection was created using ShapeWorks, capturing key morphological features, such as variations in the femoral neck-shaft and anteversion angles. Seven synthetic femurs were generated from the SSM to create SSM-informed MSMs, which were systematically evaluated through kinematics and kinetics analyses in OpenSim. Incorporating the SSM led to slight changes in the pediatric MSMs’ kinematics but …

Feasibility Of Creating A Non-Profit And Nongovernmental Organization Cybersecurity Incident Dataset Repository Using Osint, Stanley Mierzwa, Iassen Christov

Center for Cybersecurity

Organizations of all types are prone to cybersecurity and information security attacks. Non-Profit Organizations (NPOs) and Non-Governmental Organizations (NGOs) are not exempt from using information technology solutions and, thus, have been the recipient victims of cyber attackers. There exist many areas and venues where data are collected to report back annually on the status and numbers of cybersecurity attacks against many sectors of our society. The Department of Homeland Security (DHS) Cybersecurity and Infrastructure Security Agency (CISA) catalogs sixteen critical sectors that are considered vital to the United States. However, finding where the NPO and NGO community should reside with …

Integrating Digital Twin Technology For Real Time Blockage Detection In Water Cooled Electronics, Richard Scott Hainey Jr.

Theses and Dissertations

This paper presents a culmination of research into integrating Digital Twin (DT) technology in water-cooled electronic systems to improve system reliability by detecting faults in the cooling system that maintains the proper operation of heat-producing electronic components and systems. A DT is a virtual representation of a physical twin (PT). This PT can represent real-world systems, individual components, or processes. Using the DT, operators can gain insight into the behavior and characteristics of the PT, thereby facilitating informed decisions to improve its health and optimize processes. The DT system is designed to detect obstructions forming in the waste heat-producing components …

10.01.2024 Orsp Connect, Liz Williamson

ORED Newsletter

NIH Podcast on simplified review framework

LINC lunch External Review

NIDA Diversity Supplements Webinar

Burn Cost Modeling For Surface Grinding Optimization, Taiwo Fasae

Dissertations (1934 -)

Surface grinding plays a pivotal role in the machining industry, constituting roughly 25% of all machining operations worldwide. Its precision and efficiency are crucial, particularly in sectors requiring high-quality surface finishes, such as aerospace and semiconductor manufacturing. For thermal damage prevention, traditional approaches to parameter selection use thresholds to exclude burn-prone parameters. However, by omitting the cost of burn, the threshold-exclusion strategy yields outcomes that fail to reflect the true costs of grinding. This dissertation introduces a novel burn cost model that transcends these limitations, offering a more nuanced and cost-effective approach to managing grinding burn. The burn cost model …

Experimental Comparison Of Open Chamber Spark Plug And Passive Prechamber Spark Igniters On The Combustion Of Fumigated Natural Gas For Heavy Duty Engine Applications, John Richard Valla

Master's Theses (2009 -)

Methane the primary component of natural gas, has 80 times the global warming potential of CO2. As a result methane emissions regulations have rapidly increased in recent years. This posses a challenge for heavy duty spark ignited (SI) natural gas engine OEMs, in efforts to reduce methane and other criteria pollutant emissions such as NOx. Heavy duty natural gas engine OEMs are pushing engine efficiency and reducing emissions by running higher compression ratios and leaner air fuel ratios. This reduces fuel consumption and combustion temperature which decreases NOx emissions, but tends to increase methane emissions. Unfortunately, lean high compression ratio …

Effect Of Storage Time And Temperature On Aggregation Of Alzheimer's Disease Amyloid-Β Protein, Amy Veihdeffer

Theses and Dissertations

Amyloid-β protein (Aβ) is widely studied due to its key role in Alzheimer’s disease (AD) pathology. One characteristic of patients suffering from AD is the deposition of amyloid plaques comprised of Aβ aggregates, which are associated with synapse damage. Thus, studying Aβ aggregation and aggregation inhibition may provide pathological and therapeutic insights. Aggregation of Aβ is a nucleation dependent process that may be influenced by the presence of pre-formed Aβ aggregate seeds that can facilitate formation of protein aggregates. These seeds may appear during preparation or storage of monomer, posing impact on experiments that study the aggregation process and the …

In Situ Assembly Enabling Adhesive-Free Bonding Of Large Area Electronic Sensors To Concrete For Structural Health Monitoring, Emmanuel Ogunniyi, Han Liu, Austin Downey, Simon Laflamme, Caroline Bennett, William Collins, Hongki Jo, Paul Ziehl

Faculty Publications

Cracks developed in concrete infrastructure are one of the primary mechanisms that degrade their structural integrity, which may result in structural failures. Previous research on soft elastomeric capacitors (SEC) has shown their viability for structural health monitoring of structural materials, including concrete, steel, and fiberglass composites. The SEC, or its derivative version with a corrugated geometry termed corrugated SEC or cSEC, is a parallel plate capacitor. Prior work demonstrated that it was possible to directly paint the electrode interfacing with the structural material onto the structure and adhere the rest of the pre-fabricated sensor onto the wet interface, thereby eliminating …

Brushbuds: Toothbrushing Tracking Using Earphone Imus, Qiang Yang, Yang Liu, Jake Stuchbury-Wass, Kayla-Jade Butkow, Dong Ma, Cecilia Mascolo

Research Collection School Of Computing and Information Systems

Inadequate toothbrushing habits are a leading cause of oral health problems such as tooth decay. Many individuals are uncertain if they are brushing effectively or over-focusing on specific areas. While high-end electric toothbrushes can address these concerns, manual toothbrushes remain widely used due to their simplicity and affordability. In this paper, we introduce BrushBuds, an earphone-based toothbrushing monitoring system aimed at tracking brushing areas, which leverages the ubiquitous presence of earphones to enhance manual toothbrushing. BrushBuds utilizes Inertial Measurement Units (IMUs) in earphones to detect subtle head movements incurred by toothbrushing. By capturing distinct motion patterns specific to brushing for …

The Accurate Conversion Of Biological Experiments From Cesium Irradiation To X-Ray Irradiation: The Significance, Problems, And The Future Of Experimental Radiation Research, Gretchen Carpenter

Dartmouth College Master’s Theses

Preclinical small animal irradiation studies, once conducted on Cesium irradiators, are increasingly being performed with X-ray-based irradiators. The transition stems from concerns regarding national security risks, making X-ray irradiators which are compact and easy to operate an enticing alternative. However, questions regarding the relative biological effectiveness between the two sources have revealed a lack of adequate dosimetric characterization of X-ray beams, standardized protocol for dose calibration, and thorough understanding of experimental biological parameters. A literature review conducted on orthovoltage irradiators has revealed that there are over 54 different types of beam structures used, a dramatic departure from the one uniform …

Temporal Forecasting Of High-Rate Dynamic Using Physics-Informed Machine Learning And Hardware-Software Co-Design, Puja Chowdhury

Theses and Dissertations

Due to aging, fatigue, corrosion, and even natural disasters; the health of the structure is prone to degradation throughout its service life. The explosively-fast growing efforts on Structural health monitoring (SHM) always try to exploit different aspects of the automation of damage detection, localization, and prognosis tasks. One of the main challenges is the hardware and software co-design to implement the model in real-life situations. On the other hand, the fast-advancing artificial intelligence draws the researchers' attention to adopt different data-driven approaches in this field. This brings other challenges like domain-specific model adaptation, data bias, data scarcity, model validation by …

Talar And Calcaneal Coordinate Axes Definitions Across Foot Pathologies, Kassidy Knutson, Erika P. Muhlrad, Andrew C. Peterson, Thomas Leonard, Abigail M. Anderson, Katelyn C. Aragon, Zachary J. Eatough, Bruce A. Macwilliams, Karen M. Kruger, Amy L. Lenz

Biomedical Engineering Faculty Research and Publications

The understanding of foot and ankle biomechanics is improving as new technology provides more detailed information about the motion of foot and ankle bones with biplane fluoroscopy, as well as the ability to analyze the hindfoot under weightbearing conditions with weightbearing computed tomography. Three-dimensional anatomical coordinate systems are necessary to describe the 3D alignment and kinematics of the foot and ankle. The lack of standard coordinate systems across research study sites can significantly alter experimental data analyses used for pre-surgical evaluation and post-operative outcome assessments. Clinical treatment paradigms are changing based on the expanding knowledge of complex pes planovalgus morphologies …

Realtime And Noninvasive Assessment Of Endotracheal Tube Displacement Using Near-Infrared And Visible Cameras, Tongtong Lu, Pawjai Khampang, Ahmed Beydoun, Rebecca Rodhe, Wenzhou Hong, Joseph E. Kerschner, Bing Yu

Biomedical Engineering Faculty Research and Publications

Endotracheal tube (ETT) intubation is a medical procedure routinely used for achieving mechanical ventilation in critically ill patients. Appropriate ETT placement is crucial as undetected tube migration may cause multiple complications or even fatalities. Therefore, prompt detection of unplanned movement of the ETT and immediate action to restore proper placement are essential to ensure patient safety. Despite this necessity, there is not a widely adopted tool for real-time assessment of ETT displacement. We have developed a device, a dual-camera endotracheal tube or DC-ETT, to address this unmet clinical need. This device uses a near-infrared (NIR) LED and a side-firing optical …

Sex Differences In Active Avoidance And Neural Circuit Mechanisms In Contextual Fear Generalization, Carly Vincent

Theses and Dissertations

The current studies were aimed to investigate two behavioral hallmarks of anxiety and stress-related disorders, avoidance responses and the over-generalization of fear. In the first set of studies, active avoidance and extinction learning, that parallels exposure therapy in preclinical rodent models, were used. It is known that stress can influence aversive learning and extinction training, which can result in poor extinction retention. However, it is not well understood how the stress response is facilitating extinction resistance in active avoidance learning across sexes. Therefore, the first set of studies aimed to investigate the role of biological sex and glucocorticoid receptor (GR) …

Design And Application Of Redox-Mediated Flow Electrode Electrodialysis For Ion Removal And Recovery, Rongxuan Xie

Theses and Dissertations

To meet the growing demand for freshwater driven by population growth and rising living standards, the first desalination plants were established in the late 1950s. As energy costs have risen over time, research has increasingly focused on reducing the overall cost of water treatment. Electrodialysis (ED), which facilitates the migration of anions and cations across ion exchange membranes under the influence of an electric field, has gained significant attention as a treatment method for saline water and brine due to its simplicity, low cost, and scalability. However, its traditional batch operation mode and the potential for generating flammable gases have …

Autonomous Real-Time Model Updating Within Digital Twin Frameworks For Thermal Systems, Braden Robert Priddy

Theses and Dissertations

As engineering systems increase in scale and complexity in the era of the Fourth Industrial Revolution, data-driven solutions will become essential in enabling the next generation of these systems. One of the trending tools that can aid in this transition is digital twins. As physical systems degrade throughout their life cycles, their behavior also changes. Digital twins use data assimilation to continuously update virtual models to represent the current state of their physical counterparts. A reliable digital twin can be leveraged by a system operator to perform diagnostics, optimize, and tests without ever needing the physical system. However, implementing effective …

Augmented Reality (Ar) And Virtual Reality (Vr)-Based Data Visualization Frameworks For The Manufacturing Industry, Nitol Saha

Theses and Dissertations

Industry 4.0 is transforming the manufacturing industry by integrating digital technologies throughout the production lifecycle, leading to the development of smart factories. The integration of Augmented Reality (AR) and Virtual Reality (VR) alongside smart manufacturing is transforming traditional industry practices by establishing a robust cyber-physical infrastructure, enhanced data visualization, and improved task execution. This thesis aims to develop AR and VR-based data visualization frameworks for the manufacturing industry, focusing on detailed implementation strategies, initial results, and key findings of these frameworks. One major focus of these frameworks is the generalization of the technological assets so that these frameworks can be …

Real-Time Robot Pose Estimation For Industry 4.0: Enhancing Motion Validation And Monitoring With A Vision-Based Framework, Jad Samaha

Theses and Dissertations

Amidst the era of Industry 4.0, robots became integral to automated production lines by performing complex tasks with high precision and adapting to changing production needs in real-time. Therefore, ensuring their precise and reliable operation is paramount for maintaining high-quality standards and operational efficiency. This invoked the need for an automated motion validation tool that guarantees accurate program task execution, by detecting deviations or anomalies that may indicate mechanical faults or software errors. Given the exponential advancements in AI, particularly in Computer Vision, a vision-based solution is ideal for ensuring the correct positioning of a robot in real-time. Operating independently …

Development Of Avalanche Photo Detector For Uv-C Using Gallium Oxide Material System, Md Ghulam Ghulam Zakir

Theses and Dissertations

This work describes the metal-organic chemical vapor deposition (MOCVD) optimization process for epitaxially grown gallium oxide (Ga2O3) layers, electrical field distribution, and the design for Avalanche Photo Detector (APD). MOCVD is a well-accepted process in the semiconductor industry, as it is well-known for its precise deposition of ultra-thin, high-quality semiconductor layers with extraordinary control over composition and thickness. The choice of Ga2O3 is due to r its distinctive properties of ultra-wide bandgap and low turn-on resistance. Thus, Ga₂O₃-based materials can withstand high voltage and current with the least energy loss, making them an attractive choice for …

Augmented Reality Based Maintenance Operations And Training, Victor Scott Gadow

Theses and Dissertations

Augmented Reality (AR) is the process of superimposing virtual information on top of objects or other structures in the real-world environment. It is considered one of many paradigms included in the idea of smart manufacturing and can enable a mixture of the other technologies involved. A large increase in research on AR has been seen in the past decade as technologies have begun to evolve to become more robust and reliable. It has been implemented into several key areas of manufacturing such as maintenance, assembly, training, and quality control. The rise of industry 4.0 is changing how data is used …

Redefining Gas Turbine Engine Development: A Digital Twin Framework Informed By Operational Dynamics And Numerical Analysis, Sowmya Raghu

Theses and Dissertations

Gas Turbine Engines (GTEs) serve as primary propulsion systems in aviation and are key for power generation units in various industrial applications. The conventional Gas Turbine Engine Development and Monitoring Lifecycle (EDML) typically encompasses six stages: preliminary design, numerical analysis, prototyping and testing, manufacturing, systems integration, and subsequent systematic monitoring processes. This dissertation redefines the gas turbine engine design and development process by synergistically integrating design capabilities, real-time operational data, and predictive maintenance through the implementation of digital twins. The primary objective is to establish a comprehensive framework for gas turbine engine design by utilizing thermodynamic and aerodynamic modeling, supported …

Tracking Deposition And Settling Characteristics Of Airborne Metallic Particulate, William Kahale Caspino

Theses and Dissertations

Transport and deposition of metal particles is a source of environmental and public health concern. Understanding how ambient conditions and the properties of the particles interact to influence the dispersal range can provide information on and the possible extent of environmental contamination. Controlled laboratory experiments and modeling were utilized to determine when such particles would deposit. Particle samples containing heavy metals, a Palladium-dominant alloy and a Nickel/Aluminum dominant alloy LANA, were released in a static column, and the vertical displacement was tracked utilizing a Phantom v7.3 camera and a camera lens. Electron microscopy revealed that particles are not spherical and …

Vascular Calcification In A Mouse Model Of Chronic Kidney Disease And In Human Peripheral Arterial Disease, Breanna Pederson

Theses and Dissertations

Vascular calcification is a process in which calcium and phosphate crystallize to form hydroxyapatite in the extracellular matrix of blood vessels. There are two forms of arterial calcification: intimal and medial, which occur via different etiologies. Intimal calcification is associated with atherosclerosis and occurs in the layer of endothelial cells adjacent to the artery lumen. Medial arterial calcification (MAC) is independent of atherosclerosis and occurs in the middle, muscular layer of the artery. MAC is strongly associated with aging, diabetes mellitus, and chronic kidney disease (CKD). MAC is frequently in patients with peripheral arterial disease (PAD). Most studies to date …

Delivery Of Tgfβ3 From Magnetically Responsive Coaxial Fibers Reduces Spinal Cord Astrocyte Reactivity In Vitro, Jessica L. Funnell, Jasper Fougere, Diana Zahn, Silvio Dutz, Ryan J. Gilbert

Chemical and Biochemical Engineering Faculty Research & Creative Works

A spinal cord injury (SCI) compresses the spinal cord, killing neurons and glia at the injury site and resulting in prolonged inflammation and scarring that prevents regeneration. Astrocytes, the main glia in the spinal cord, become reactive following SCI and contribute to adverse outcomes. The anti-inflammatory cytokine transforming growth factor beta 3 (TGFβ3) has been shown to mitigate astrocyte reactivity; however, the effects of prolonged TGFβ3 exposure on reactive astrocyte phenotype have not yet been explored. This study investigates whether magnetic core-shell electro spun fibers can be used to alter the release rate of TGFβ3 using externally applied magnetic fields, …