Digital Commons Network^™

Development Of A Rapidly Computable Descriptor Of Prostate Tissue Temperature During Transurethral Conductive Heat Therapy For Benign Prostate Hyperplasia, U H. Patel, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Benign prostate hyperplasia (BPH) is a condition in older men in which the mass of tissue in the prostate gland gradually increases over the course of many years, ultimately leading to urinary outflow obstruction. Current treatment of this condition is to surgically remove the obstructing tissue. One novel alternative therapy being studied is transurethral thermocoagulation of excessive prostatic mass. In this approach, a heat emitting catheter is placed in the prostatic urethra, and the intraprostatic segment of the catheter is heated to temperatures above 60 oC for one hour. Two dimensional cylindrical coordinate computer simulations of this treatment modality were …

Impedance Spectroscopy As A Nondestructive Health Interrogation Tool For Lithium-Bcx Cells, Branko N. Popov, W. Zhang, E. C. Darcy, Ralph E. White

Faculty Publications

The objective of this investigation was to study the growth of thick passivating layers on the Li anode in Li/BCX(Li/SOCl₂ + BrCl) cells which were stored for a period of 3 years. Impedance spectroscopy and equivalent circuit models were used to determine characterizing parameters for these cells. The equivalent circuit used for virgin cells includes a faradic contribution and diffusion of the electroactive species. The equivalent circuit for batteries stored 1 or 2 years includes the impedance of a metal/passive film interface, the resistance of the film, and the impedance of the passivating film/electrolyte interface. The equivalent circuit used …

Chemical Tracing Techniques For Evaluating Rill Hydraulics, John E. Gilley, Eugene R. Kottwitz

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Development of water erοsiοn and surface water quality control practices requires information concerning the hydraulic characteristics of upland areas. The relatively small flow rates normally found within rills make measurement of hydraulic parameters difficult. Chemical tracing procedures, originally developed for stream and river systems, have been successfully used to measure rill flow properties. A chemical tracer of known concentration is added to the rill and by knowing the degree of dilutiοn at a downstream sampling point, flow rate can be calculated. Rill flow velocity can be measured by determining the time required for a slug of tracer material to travel …

Candi (Chemical And Irrigation Management) Users Manual, Vs 2.0., A. H. Aly, Richard C. Peralta

Civil and Environmental Engineering Faculty Publications

This manual describes an interactive computer model, CANOl. CANOl is a decision support tool designed to aid in on-farm pesticides and irrigation management. CANOl simulates downward chemical movement through the soil in response to different irrigation practices. CANOl estimates the relative amount of a non-polar organic chemical which remains in the soil profile by the time it reaches a specified depth. Future releases of CANOl will involve the management of different types of chemicals. CANOl is also able to delineate the wellhead protection areas for domestic wells. For this purpose, CANOl involves USEPA's model (MWCAP). Different versions of CANOl handle …

High-Level Expression Of A Heterologous Protein In The Milk Of Transgenic Swine Using The Cdna Encoding Human Protein C, William H. Velander, John L. Johnson, Raymond L. Page, Christopher G. Russell, Anuradha Subramanian, Tracy D. Wilkins, Francis C. Gwazdauskas, Christoph Pittius, William N. Drohan

William H. Velander Publications

Transgenic pigs were generated that produced human protein C in their milk at up to 1 g/liter. The gene construct was a fusion gene consisting of the cDNA for human protein C inserted into the first exon of the mouse whey acidic protein gene. These results demonstrate that the mouse whey acidic protein gene contains regulatory elements that can direct cDNA expression at high levels in the pig mammary gland. Recombinant human protein C that was produced at about 380 pg/ml per hr in transgenic pig milk possessed anticoagulant activity that was equivalent to that of protein C derived from …

Acuta Enews December 1992, Vol. 21, No. 12

ACUTA Newsletters

In This Issue

Regulatory update

President's column

Dual routing protects Duke

Talking clock "tells" time

Seminar ratings

Director's column

10th Conference On Senior Engineering Design Projects, College Of Engineering And Applied Sciences

Senior Engineering Design Conference

The 10th Conference on Senior Engineering Design Projects was held on December 8, 1992 at the College of Engineering and applied Sciences on the Parkview Campus of Western Michigan University. The college sponsors the conference to showcase the work of its graduating seniors, who are required to complete a capstone project that puts into practice what they have learned. Many of the projects are sponsored by business and industry.

High-Level Expression Of A Heterologous Protein In The Milk Of Transgenic Swine Using The Cdna Encoding Human Protein C, William H. Velander, John L. Johnson, Raymond L. Page, Chritopher G. Russell, Anuradha Subramanian, Tracy D. Wilkins, Francis C. Gwazdauskas, Christoph Pittus, William N. Drohan

Papers in Biotechnology

Transgenic pigs were generated that produced human protein C in their milk at up to 1 g/liter. The gene construct was a fusion gene consisting of the cDNA for human protein C inserted into the first exon of the mouse whey acidic protein gene. These results demonstrate that the mouse whey acidic protein gene contains regulatory elements that can direct cDNA expression at high levels in the pig mammary gland. Recombinant human protein C that was produced at about 380 pg/ml per hr in transgenic pig milk possessed anticoagulant activity that was equivalent to that of protein C derived from …

Spectral And Spatial Pattern Recognition In Digital Memory, John M. Amrine

Theses and Dissertations

The main purpose of this research is to develop a model that can be used to solve combined spectral and spatial pattern recognition problems. The basis of my model is a multiobjective discrete programming model developed by Benabdullah and Wright (B and W). The model will be modified and then tested by solving a real world problem with SPOT multispectral imagery. Several improvements were added to the B and W model, namely standard border length accounting and control over which pixels are selected by the model. The model was also improved to process more than one channel of imagery at …

A Toposcopic Investigation Of Brain Electrical Activity Induced By Motion Sickness, Dwight A. Roblyer

Theses and Dissertations

A toposcope was constructed as a new tool to study signal frequency and phase relationships in electroencephalogram (EEG) records collected while subjects were experiencing motion sickness. This new tool, named TOPOS, is a software-based, multi-featured version of Grey Walter and Harold Shipton's device which they first produced in the late 1940s. The TOPOS graphical display permits the study of instantaneous frequency relationships between the input channels and a reference signal of fixed or varying frequency. TOPOS adds a correlation grid to aid observers in detecting channel-to-reference correlation levels. Users can also vary several display parameters via menus to optimize the …

An Assessment Of Software Safety As Applied To The Department Of Defense Software Development Process, Peter W. Colan, Robert W. Prouhet

Theses and Dissertations

This research analyzed the relationships between the DOD software development process, system safety requirements, and current structured software safety analysis techniques. The current state of software safety was assessed within the aerospace industry and DOD, and a training program for DOD System Safety Managers was developed. A telephone survey was conducted to gather information on current software safety analysis techniques and methodologies. Personal interviews were conducted with Aeronautical System Center System Safety Managers to gather data on job perception and perceived training needs. The results of the study indicate that the DOD guidance and policy documents needed to implement and …

Strategies For Optimal Control Design Of Normal Acceleration Command Following On The F-16, James C. Baird

Theses and Dissertations

Weight shapes and locations are investigated for H₂, H_∞, and the general mixed H2/H infinity optimization methodologies. The design model is normal acceleration command following for the F-16 (SISO) at Mach 0.6 and Sea Level, which yields a nonminimum phase and unstable plant. H₂ design types include LQG, LQG/Sensitivity, and LQG/Tracking. Robustness and tracking are the objectives of the central H infinity process. Both H_∞ optimal and suboptimal controllers are examined, with the suboptimal controller shown as the practical choice for this plant. The mixed H₂/H_∞ setup allows the tradeoff between …

Characterization Of Stall Inception In High-Speed Single-Stage Compressors, Keith M. Boyer

Theses and Dissertations

Two single-stage, transonic compressor designs were tested under various undistorted operating conditions to characterize the process leading up to aerodynamic stall. The rig case was instrumented with eight high-response static pressure transducers equally spaced around the annulus for stall development detection. High-response measurements were low-pass filtered and both spatially and temporally analyzed using discrete Fourier techniques. At all speeds tested for both designs, stall inception was characterized by growth of a small amplitude' rotating wave. The waves did not grow significantly until just prior to the instability, when exponential growth into fully-developed rotating stall occurred very rapidly, within 6-10 rotor …

Bs News

Building Services Engineering

No abstract provided.

A Model Of Global Positioning System (Gps) Master Control Station (Mcs) Operations, David N. Koster

Theses and Dissertations

The United States Air Force's Navstar Global Positioning System (GPS) provides high-accuracy space-based navigation and time distribution to suitably- equipped military and civilian users. The system consists of earth-orbiting satellites and a world-wide network of ground stations. A single operational control center, the GPS Master Control Station (MCS) monitors, maintains, and commands the GPS satellite constellation. The on-going deployment of the complete satellite constellation and recent changes in the operational crew structure may invalidate previously used planning and management paradigms. There is currently no analytical method for predicting the impact of these and other environmental changes on system parameters and …

Oxidative Mechanisms In Arterial Distension Injury: Observations Relevant To Restenosis After Angioplasty, Charles F. Babbs, Yuan Zhong

Weldon School of Biomedical Engineering Faculty Working Papers

Background: To explore the hypothesis that tissue iron and reactive oxygen species, including superoxide (O2), mediate acute inflammatory and late hyperplastic responses to vascular injury, we studied experimental overdistension of normal carotid and femoral arteries in dogs. Experimental design: Arterial segments isolated in situ were distended with Ringer solution at 2 atmospheres pressure. In initial experiments the arteries were excised immediately after distension and immersed in diaminobenzidine solutions containing Mn++ ions to initiate histochemical reactions for O2. In other experiments distended arterial segments were reperfused with arterial blood in the presence or absence of the iron chelator, deferoxamine, or the …

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 8, Number 8, November 1992, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

A fourteen page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

Structural Ceramic Incorporating Boron Carbide Whiskers For The Strengthening Thereof, P. D. Ownby, J. Liu

Materials Science and Engineering Faculty Research & Creative Works

Ceramic composites, and in particular structural ceramic composites, have enhanced strength, toughness and abrasion resistance due to the presence of up to about 40 volume percent of relatively large boron carbide whiskers. Although whiskers of various sizes were studied, those of particular interest are whiskers having an average diameter greater than about 3 micrometers, and particularly about 5 to about 8 micrometers, with an average aspect ratio of about 50. Due to the larger size, which had been predicted to be detrimental, there is less respiratory health risk when using these whiskers in the manufacturing of thse improved ceramic composites. …

Bs News

Building Services Engineering

No abstract provided.

Southern Nevada Effluent Wetlands: A Proposed Cooperative Venture Between The Bureau Of Reclamation & City Of Las Vegas, Bureau Of Reclamation

Publications (WR)

Throughout North America there is a growing interest in constructed wetlands, both as relatively inexpensive, low-maintenance systems for removing nutrients from wastewater, and as a means of using municipal wastewater to enhance wildlife habitat and create public use opportunities. Because wetlands appear to have good potential as a component in the overall management of scarce water resources, the Bureau of Reclamation (Reclamation) has undertaken several cooperative research and demonstration projects to evaluate their effectiveness in a variety of local environments. While a number of projects have demonstrated that wetlands can be beneficially employed to improve water quality, few such projects …

Quantitative Assessment Of Myocardial Oxygen Supply And Demand Using A Dynamic Model Of The Cardiovascular System, Badrinath R. Puranic

Theses

A quantitative understanding of the changes in coronary, pulmonary and systemic hemodynamic variables and their effect on myocardial supply and demand is important to the better management of anesthetic care of patients with impaired cardiac function. Animal studies have identified those hemodynamic factors that play an important role in determining the balance between oxygen supply and demand for the myocardium. These include myocardial contractility, left ventricular end-diastolic volume, systemic arterial pressure, systemic vascular resistance, and heart rate. The interactions of these factors are complex and their combined effects on myocardial oxygen supply and demand are difficult to predict a priori. …

Mathematical Model And Simulation Of The Progression Of Cutaneous T-Cell Lymphoma, Maria L. Agostinho

Theses

A simple mathematical model and simulation of the progression of cancer with particular emphasis on Cutaneous T Cell Lymphoma was investigated. The mathematical model consists of a set of differential equations that first satisfies the homeostasis levels of the different components present and second predicts the dynamics during a diseased or unhealthy condition. The simulation was done using a FORTRAN program for integrating the differential equations.

Simulation of the immune system is important in evaluating the usefulness of particular sorts of biologically targeted therapies and in selecting the most promising treatment strategies for clinical trials. In particular, the effects of …

Catalytic Ozone/Ultraviolet Light Oxidation Of Organics In Water : Integrated Charcoal/Ozonation/Uv Radiation, Dawei Wang

Theses

A novel heterogeneous catalytic-oxidation technology where activated carbon is used as a catalyst-adsorbent, ozone serves as the oxidant and UV light as activation agent, is developed in a lab scale study. We demonstrate this process for destruction of recalcitrant organics in water i.e: combined oxidation by ozone, UV light plus activated carbon. The investigation includes evalution of various operating conditions: ozone levels, activated carbon levels; time for complete destruction of the individual target pollutants, plus evalution of activity of the continuously recativated carbon surface in-situ. All experiments were performed at room temperature in a semi-batch reactor. Seven representative chemicals was …

Computation Of Collision Parameters Of Spheres By Computer Vision, Sumit Sen

Theses

Collision parameter evaluation of rigid spherical particles requires estimation of pre- and post-impact position, velocity and angular velocity vectors of colliding particles. A three dimensional experimental technique is devised where the instantaneous position and orientation of the particles are determined by analyzing frames obtained through high speed video imaging system. Since the image obtained is two dimensional, a mirror setting is designed to capture two orthogonal views of collision in order to estimate motion in depth. The translational velocity vector is determined from the position information extracted through application of available image analysis techniques over two time frames of digitized …

1992 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

Santa Clara Magazine, Volume 35 Number 1, Fall 1992, Santa Clara University

Santa Clara Magazine

11 - SENIOR SEMINAR Elderhostel brings a different kind of student to Santa Clara. By Christine Spielberger '69

14 - DAYS RICH WITH EMPTINESS A noted Catholic writer reflects on his annual retreat to a Trappist abbey, a respite from the daily stress of getting and spending. In a related article, he discusses "The Inner Experience," an unpublished book by Thomas Merton that examines the modern contemplative lifestyle. By Mitch Finley '73

22 - WHAT'S WRONG WITH THIS PICTURE? The image of an all -male Senate committee weighing the merits of Anita Hill 's charges against Clarence Thomas spurred a …

The Calendar - October 1992, Nova University

The Calendar

No abstract provided.

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 8, Number 7, October 1992, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

A ten page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

Bulletin - Fall, 1992, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Retention Of Cellular Viability And Growth Potential In Cryopreserved Bovine Arterial Tissue: Implications For Clinical Use Of Cryopreserved Vascular Allografts, Kip G. Gardner

Biological Sciences Theses & Dissertations

Segments of bovine calf aortas and pulmonary arteries were cryopreserved at -196° C for two weeks to 18 months and subsequently thawed. Cellular morphology, viability, and growth potential in these segments were then compared with the same attributes in segments from fresh (control) arteries. Scanning electron microscopy revealed no disruption of intimal surfaces attributable to cryopreservation. Endothelial cells were successfully cultured from all cryopreserved arterial segments. Endothelial monolayers grown from cryopreserved arteries had a cobblestone appearance and expressed Factor VIII antigen but not smooth muscle alpha-actin. Plating efficiency in primary cultures of endothelial cells was lower for cryopreserved arteries than …