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Identification Of Hysteretic Systems With Slip Using Bootstrap Filter, S. J. Li, Yoshiyuki Suzuki, Mohammad N. Noori Jul 2004

Identification Of Hysteretic Systems With Slip Using Bootstrap Filter, S. J. Li, Yoshiyuki Suzuki, Mohammad N. Noori

Office of the Dean (CENG) Scholarship

Hysteretic models with slip are frequently used to predict the non-linear behaviour of many structural systems, for example wood buildings and reinforced concrete structures. A model, called SL model, which can describe the pinching of most practical hysteresis loops perfectly was proposed by Baber and Noori. This model is characterised by control parameters that have to be identified from observed experimental data. A method of estimating the parameters of SL model on the basis of input–output data based on Bayesian state estimation and bootstrap filter is suggested in this paper, which has the great advantages of being able to handle …


Santa Clara Magazine, Volume 46 Number 1, Summer 2004, Santa Clara University Jul 2004

Santa Clara Magazine, Volume 46 Number 1, Summer 2004, Santa Clara University

Santa Clara Magazine

8 - A PUZZLING PROFESSOR By Adam Breen. Byron Walden, an assistant professor of mathematics at SCU, draws on his knowledge of numerical analysis to create crossword puzzles for The New York Times.

10 - THE LAUNCHING PAD By Larry Sokoloff J.D. '92. Top government agencies, other universities, and companies are relying on the University's Robotics Systems Lab-and its students-to build and monitor satellites.

16 - A NOVEL TEAM By Kristin Lenore '04. The University's publishing partnership with Heyday Books aims to help preserve California's cultural legacy.


Impulse, Dave Graves, Kyle Johnson, Greta Stewart, Denise Watt Jul 2004

Impulse, Dave Graves, Kyle Johnson, Greta Stewart, Denise Watt

Impulse (Jerome J. Lohr College of Engineering Publication)

Features:
[Page] 2 Expo's physics wizard captures attention of high schoolers: The "Wonders of Science" never get old for Professor Larry Browning.
[Page] 4 Science and Engineering Fair: The campus attracts nearly 500budding scientists every year
[Page] 6 Key donation, cooperation create observatory at Oak Lake: Two remotely controlled telescopes will be in operation the fall.
Faculty:
[Page] 8 A Storry worth telling: Co-workers and former students remember late dean Junis Storry.
[Page] 10 Math Professor Ken Yocom isn't about to retire: Long-time department head has taken a new position.
[Page] 12 Dennis Loban is remembered for quality and …


Transparency Tube Provides Reliable Measure Of Water Clarity And Suspended Solids Concentration In California Waterways, Gary M. Litton, R. Dahlgren, E. V. Nieuwenhuyse Jul 2004

Transparency Tube Provides Reliable Measure Of Water Clarity And Suspended Solids Concentration In California Waterways, Gary M. Litton, R. Dahlgren, E. V. Nieuwenhuyse

All Faculty Articles - School of Engineering and Computer Science

We examined the efficacy of using transparency-tube measurements to estimate turbidity, total suspended solids (TSS) and particulate nitrogen and phosphorus concentrations in several California waterways. Just as lowering a black-and-white disk (Secchi disk) into a lake provides a convenient way to measure its water clarity, a transparency tube offers a practical alternative for measuring water clarity and suspended solids concentrations in California streams and waterways. While transparency relationships with turbidity and TSS are strongest within a given sampling location, these relationships are relatively robust across a wide range of water bodies displaying contrasting conditions. However, transparency-tube measurements appear to have …


A Nebraska Odor Footprint Tool For Planning Pork Facilities, Richard Koelsch Jul 2004

A Nebraska Odor Footprint Tool For Planning Pork Facilities, Richard Koelsch

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Pork producers and rural communities are struggling to balance air quality issues (primarily odors) with the presence and growth of the industry. Currently the type of pork facility, odor control measures, prevailing wind direction, atmospheric conditions, and a community's tolerance to some degree of odor are largely ignored in the planning process because scientific tools that incorporate this information are lacking. Without such tools, decisions on setback distances and acceptable type and size of facilities are influenced by a range of arguments, often emotional in nature. In addition, pork producers lack tools to assist in evaluating impact on a rural …


Inside Unlv, Holly Ivy De Vore, Carol C. Harter, Stuart Mann Jul 2004

Inside Unlv, Holly Ivy De Vore, Carol C. Harter, Stuart Mann

Inside UNLV

No abstract provided.


Energy-Landscape-Model Analysis For Irreversibility And Its Pulse-Width Dependence In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, R. P. Joshi, Q. Hu, Karl H. Schoenbach, Stephen J. Beebe Jul 2004

Energy-Landscape-Model Analysis For Irreversibility And Its Pulse-Width Dependence In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, R. P. Joshi, Q. Hu, Karl H. Schoenbach, Stephen J. Beebe

Bioelectrics Publications

We provide a simple, but physical analysis for cell irreversibility and apoptosis in response to an ultrashort (nanosecond), high-intensity electric pulse. Our approach is based on an energy landscape model for determining the temporal evolution of the configurational probability function p(q). The primary focus is on obtaining qualitative predictions of a pulse width dependence to apoptotic cell irreversibility that has been observed experimentally. The analysis couples a distributed electrical model for current flow with the Smoluchowski equation to provide self-consistent, time-dependent transmembrane voltages. The model captures the essence of the experimentally observed pulse-width dependence, and provides a possible physical picture …


Impact Of Pulmonary Arterial Endothelial Cells On Duroquinone Redox Status, Marilyn P. Merker, Robert D. Bongard, Gary S. Krenz, Hongtao Zhao, Viola S. Fernandes, Balaraman Kalyanaraman, Neil Hogg, Said H. Audi Jul 2004

Impact Of Pulmonary Arterial Endothelial Cells On Duroquinone Redox Status, Marilyn P. Merker, Robert D. Bongard, Gary S. Krenz, Hongtao Zhao, Viola S. Fernandes, Balaraman Kalyanaraman, Neil Hogg, Said H. Audi

Biomedical Engineering Faculty Research and Publications

The study objective was to use pulmonary arterial endothelial cells to examine kinetics and mechanisms contributing to the disposition of the quinone 2,3,5,6-tetramethyl-1,4-benzoquinone (duroquinone, DQ) observed during passage through the pulmonary circulation. The approach was to add DQ, durohydroquinone (DQH2), or DQ with the cell membrane-impermeant oxidizing agent, ferricyanide (Fe(CN)63−), to the cell medium, and to measure the medium concentrations of substrates and products over time. Studies were carried out under control conditions and with dicumarol, to inhibit NAD(P)H:quinone oxidoreductase 1 (NQO1), or cyanide, to inhibit mitochondrial electron transport. In control cells, DQH2 appears …


Effect Of Ventilation Rate On Instilled Surfactant Distribution In The Pulmonary Airways Of Rats, Joseph C. Anderson, Robert C. Molthen, Christopher A. Dawson, Steven Thomas Haworth, Joseph L. Bull, Matthew R. Glucksburg, James B. Grotberg Jul 2004

Effect Of Ventilation Rate On Instilled Surfactant Distribution In The Pulmonary Airways Of Rats, Joseph C. Anderson, Robert C. Molthen, Christopher A. Dawson, Steven Thomas Haworth, Joseph L. Bull, Matthew R. Glucksburg, James B. Grotberg

Biomedical Engineering Faculty Research and Publications

Liquid can be instilled into the pulmonary airways during medical procedures such as surfactant replacement therapy, partial liquid ventilation, and pulmonary drug delivery. For all cases, understanding the dynamics of liquid distribution in the lung will increase the efficacy of treatment. A recently developed imaging technique for the study of real-time liquid transport dynamics in the pulmonary airways was used to investigate the effect of respiratory rate on the distribution of an instilled liquid, surfactant, in a rat lung. Twelve excised rat lungs were suspended vertically, and a single bolus (0.05 ml) of exogenous surfactant (Survanta, Ross Laboratories, Columbus, OH) …


Stent Design Properties And Deployment Ratio Influence Indexes Of Wall Shear Stress: A Three-Dimensional Computational Fluid Dynamics Investigation Within A Normal Artery, John F. Ladisa, Lars E. Olson, Ismail Guler, Douglas Anthony Hettrick, Said H. Audi, Judy R. Kersten, David C. Warltier, Paul S. Pagel Jul 2004

Stent Design Properties And Deployment Ratio Influence Indexes Of Wall Shear Stress: A Three-Dimensional Computational Fluid Dynamics Investigation Within A Normal Artery, John F. Ladisa, Lars E. Olson, Ismail Guler, Douglas Anthony Hettrick, Said H. Audi, Judy R. Kersten, David C. Warltier, Paul S. Pagel

Biomedical Engineering Faculty Research and Publications

Restenosis limits the effectiveness of stents, but the mechanisms responsible for this phenomenon remain incompletely described. Stent geometry and expansion during deployment produce alterations in vascular anatomy that may adversely affect wall shear stress (WSS) and correlate with neointimal hyperplasia. These considerations have been neglected in previous computational fluid dynamics models of stent hemodynamics. Thus we tested the hypothesis that deployment diameter and stent strut properties (e.g., number, width, and thickness) influence indexes of WSS predicted with three-dimensional computational fluid dynamics. Simulations were based on canine coronary artery diameter measurements. Stent-to-artery ratios of 1.1 or 1.2:1 were modeled, and computational …


Interactive Land Use Vrml Application Using Servlet Assist, Suresh Chitithoti Jul 2004

Interactive Land Use Vrml Application Using Servlet Assist, Suresh Chitithoti

Electrical & Computer Engineering Theses & Dissertations

The integration of VRML and Servlet technologies has the potential to revolutionize web-based simulation visualization. The Interactive Land Use VRML Application (ILUVA) uses Java Servlets enabling one to perform urban planning by taking a virtual land area and add buildings, roadways, landscaping, and other features. The Virtual Reality Modeling Language (VRML) is a web-based technology for specifying and delivering interactive three-dimensional visualizations over a browser. The Java Servlet technology offers several powerful capabilities such as user authentication, session management, database connectivity for maintaining several possibly simultaneous user sessions, and dynamically generated VRML. Save and restore capabilities for any applications are …


Modeling Nerve Electro-Stimulation In The Nanosecond Regime, Feng Chen Jul 2004

Modeling Nerve Electro-Stimulation In The Nanosecond Regime, Feng Chen

Electrical & Computer Engineering Theses & Dissertations

Numerical simulations of electrical stimulation of frog gastrocnemius muscles have been carried out for pulse durations in the nanosecond regime. There are a number of potential advantages in using ultra-short pulses for neural stimulation, and no previous electro-stimulation work in the sub-microsecond regime has been reported. A timedependent, three-dimensional analysis model was developed and implemented for three distinct situations: (i) direct stimulation via electrode contact, (ii) indirect excitation based on electrodes immersed in a saline-filled bath, and (iii) remote electromagnetic stimulation through vacuum. The simulations yielded strength-dm ation (S-D) curves with pulse durations as short as 5 ns. Good agreement …


Brain Motion And Deformation During Closed Head Injury In The Presence Of Cerebrospinal Fluid, Charles F. Babbs Jun 2004

Brain Motion And Deformation During Closed Head Injury In The Presence Of Cerebrospinal Fluid, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

This paper presents a new analysis of the physics of closed head injury following brief, intense acceleration of the head. It focuses upon the buoyancy of the brain in cerebrospinal fluid, which protects against damage, the propagation of strain waves through the brain substance, which causes damage, and the concentration of strain in critical anatomic regions, which magnifies damage. Numerical methods are used to create animations or "movies" of brain motion and deformation. Initially a 1 cm gap filled with cerebrospinal fluid (CSF) separates the brain from the skull. Whole head acceleration induces artificial gravity within the skull. The brain …


Spinning Continuous Fibers For Nanotechnology, Yuris A. Dzenis Jun 2004

Spinning Continuous Fibers For Nanotechnology, Yuris A. Dzenis

Department of Engineering Mechanics: Faculty Publications

Nanotubes of carbon and other materials are arguably the most fascinating materials playing an important role in nanotechnology today. Their unique mechanical, electronic, and other properties are expected to result in revolutionary new materials and devices. However, these nanomaterials, produced mostly by synthetic bottom-up methods, are discontinuous objects, and this leads to difficulties with their alignment, assembly, and processing into applications. Partly because of this, and despite considerable effort, a viable carbon nanotube–reinforced supernanocomposite is yet to be demonstrated. Advanced continuous fibers produced a revolution in the field of structural materials and composites in the last few decades as a …


Emissions Pathways, Climate Change, And Impacts On California, Katherine Hayhoe, Daniel Cayan, Christopher B. Field, Peter C. Frumhoff, Edwin P. Maurer, Norman L. Miller, Susanne C. Moser, Stephen H. Schneider, Kimberly Nicholas Cahill, Elsa E. Cleland, Larry Dale, Ray Drapek, R. Hanemann, Laurence S. Kalkstein, James Lenihan, Claire K. Lunch, Ronald P. Nielson, Scott C. Sheridan, Julia H. Verville Jun 2004

Emissions Pathways, Climate Change, And Impacts On California, Katherine Hayhoe, Daniel Cayan, Christopher B. Field, Peter C. Frumhoff, Edwin P. Maurer, Norman L. Miller, Susanne C. Moser, Stephen H. Schneider, Kimberly Nicholas Cahill, Elsa E. Cleland, Larry Dale, Ray Drapek, R. Hanemann, Laurence S. Kalkstein, James Lenihan, Claire K. Lunch, Ronald P. Nielson, Scott C. Sheridan, Julia H. Verville

Civil, Environmental and Sustainable Engineering

The magnitude of future climate change depends substantially on the greenhouse gas emission pathways we choose. Here we explore the implications of the highest and lowest Intergovernmental Panel on Climate Change emissions pathways for climate change and associated impacts in California. Based on climate projections from two state-of-the-art climate models with low and medium sensitivity (Parallel Climate Model and Hadley Centre Climate Model, version 3, respectively), we find that annual temperature increases nearly double from the lower B1 to the higher A1fi emissions scenario before 2100. Three of four simulations also show greater increases in summer temperatures as compared with …


Use Of Collaborative Learning Exercises To Increase Student Motivation And Learning In An Introduction To Materials Engineering Course, Stacy Gleixner, Hilary Lackritz Jun 2004

Use Of Collaborative Learning Exercises To Increase Student Motivation And Learning In An Introduction To Materials Engineering Course, Stacy Gleixner, Hilary Lackritz

Faculty Publications

A collection of collaborative, in-class exercises have been designed for use in a freshmen/sophomore level Introduction to Materials Science and Engineering class. The activities are team based problems that include open ended design problems, calculation questions, and thought problems on unanswered research questions. The activities have been designed with the goal of having one or two a week embedded in a more traditional lecture setting. The exercises relate to the topics covered in most standard Introduction to Materials classes (crystal structure, mechanical properties, polymers, phase diagrams…). Each activity is designed specifically to engage the students in the lecture and excite …


Life Cycle Assessment As A Tool For Green Manufacturing Education, Trevor S. Harding Jun 2004

Life Cycle Assessment As A Tool For Green Manufacturing Education, Trevor S. Harding

Materials Engineering

The design and production of engineering products that have a reduced impact on the environment and human health has increasingly become a strategic goal of corporations. Consequently, starting engineers will need to be educated in green design techniques. One method that is particularly attractive to engineers is Life Cycle Assessment (LCA). LCA is an objective approach to evaluating the environmental burden of a product, process or activity by identifying and quantifying material and energy usage and waste outputs at every life stage. LCA involves three steps: identification of scope of analysis, life cycle inventory, and impact analysis. Such an approach …


Aaas Lecture Series On Women In Science And Engineering, Maribel Vazquez Jun 2004

Aaas Lecture Series On Women In Science And Engineering, Maribel Vazquez

Publications and Research

The winning essay for a Travel Award from the American Association for the Advancement in Science Women Lecture Series.

http://ehrweb.aaas.org/womeninscience/essays/vazquez.htm


Flight Physician - June, 2004, Civil Aviation Medical Association Jun 2004

Flight Physician - June, 2004, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twenty page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


Ascertaining The Importance Of Neurons To Develop Better Brain-Machine Interfaces, Justin C. Sanchez, Jose M. Carmena, Mikhail A. Lebedev, Miguel A.L. Nicolelis, John G. Harris, Jose C. Principe Jun 2004

Ascertaining The Importance Of Neurons To Develop Better Brain-Machine Interfaces, Justin C. Sanchez, Jose M. Carmena, Mikhail A. Lebedev, Miguel A.L. Nicolelis, John G. Harris, Jose C. Principe

Electrical and Computer Engineering Faculty Research & Creative Works

In the design of brain-machine interface (BMI) algorithms, the activity of hundreds of chronically recorded neurons is used to reconstruct a variety of kinematic variables. A significant problem introduced with the use of neural ensemble inputs for model building is the explosion in the number of free parameters. Large models not only affect model generalization but also put a computational burden on computing an optimal solution especially when the goal is to implement the BMI in low-power, portable hardware. In this paper, three methods are presented to quantitatively rate the importance of neurons in neural to motor mapping, using single …


Prediction Of Growth Factor Effects On Engineered Cartilage Composition Using Deterministic And Stochastic Modeling, Sean S. Kohles, Asit K. Saha, J. (Jagannath) Mazumdar Jun 2004

Prediction Of Growth Factor Effects On Engineered Cartilage Composition Using Deterministic And Stochastic Modeling, Sean S. Kohles, Asit K. Saha, J. (Jagannath) Mazumdar

Mechanical and Materials Engineering Faculty Publications and Presentations

In the design of engineered tissues, guided balance of biomaterial degeneration with tissue synthesis offers refined control of construct development. The objective of this study was to develop a mathematical model that describes the steady state metabolism of extracellular matrix molecules (ECM: glycosaminoglycan and collagen) in an engineered cartilage construct taking into account localized environmental changes that may arise because of the application of growth factors. The variable effects of growth factors were incorporated in the form of random noise rather than the difference in rates of synthesis and catabolism. Thus, the frequency of ECM accumulation for each matrix molecule …


Effect Of Gender And Defensive Opponent On The Biomechanics Of Sidestep Cutting, Scott G. Mclean, Susanne W. Lipfert, Antonie J. Van Den Bogert Jun 2004

Effect Of Gender And Defensive Opponent On The Biomechanics Of Sidestep Cutting, Scott G. Mclean, Susanne W. Lipfert, Antonie J. Van Den Bogert

Mechanical Engineering Faculty Publications

Purpose: Anterior cruciate ligament (ACL) injuries often occur in women during cutting maneuvers to evade a defensive player. Gender differences in knee kinematics have been observed, but it is not known to what extent these are linked to abnormal neuromuscular control elsewhere in the kinetic chain. Responses to defense players, which may be gender-dependent, have not been included in previous studies. This study determined the effects of gender and defense player on entire lower extremity biomechanics during sidestepping.

Methods: Eight male and eight female subjects performed sidestep cuts with and without a static defensive opponent while 3D motion and ground …


Performance Of Self-Compacting Concrete, Mohamed Samir Rushdy Jun 2004

Performance Of Self-Compacting Concrete, Mohamed Samir Rushdy

Archived Theses and Dissertations

Concrete compaction is one of the indispensable fundamentals of concrete manufacturing. However, thorough compaction cannot always be insured. This can be wholly or partially encountered in congested sections, out-of reach deep foundations and narrow or irregular precast components. On the other hand, typical vibrators were considered as contributor to health hazards to workers. Self-compacting concrete (SCC) is an emerging concrete where the cohesive yet flowable consistency of the concrete itself secures adequate placement with high level of homogeneity and little or no segregation. Such concrete is primarily achieved by incorporating admixtures that is referred to as viscosity modifying (VM) admixtures …


Inside Unlv, Holly Ivy De Vore, Caryn Key, Carol C. Harter, Richard Morgan Jun 2004

Inside Unlv, Holly Ivy De Vore, Caryn Key, Carol C. Harter, Richard Morgan

Inside UNLV

No abstract provided.


An Assessment Of Modern Methods For Rotor Track And Balance, Michael J. Renzi Jun 2004

An Assessment Of Modern Methods For Rotor Track And Balance, Michael J. Renzi

Theses and Dissertations

One routine maintenance item facing the helicopter industry today is the issue of rotor track and balance (RT&B). While the task of reducing vibrations is often overlooked as simply an unimportant maintenance concern, what should not be overlooked is the extensive amount of time and money committed by maintenance to smoothing an aircraft. If there were a way to make the process of rotor track and balance more efficient it would be a huge boost to the helicopter industry in both time and money. The first steps towards research into new and improved methods is to evaluate what is currently …


Computerized Biofeedback Knee Goniometer: Acceptance And Effect On Exercise Behavior In Post-Total Knee Arthroplasty Rehabilitation, Todd A. Kuiken, Hagay Amir, Robert A. Scheidt Jun 2004

Computerized Biofeedback Knee Goniometer: Acceptance And Effect On Exercise Behavior In Post-Total Knee Arthroplasty Rehabilitation, Todd A. Kuiken, Hagay Amir, Robert A. Scheidt

Biomedical Engineering Faculty Research and Publications

Objective

To assess device accuracy, patient acceptance, and effect of a computerized biofeedback knee goniometer (CBG), on patients’ compliance with active range of motion (AROM) exercises after total knee arthroplasty (TKA).

Design

Two-stage study: measurement validation on asymptomatic controls and an unblinded, multiple crossover trial.

Setting

Inpatient rehabilitation.

Participants

Asymptomatic controls (n=14) and post-TKA inpatients (n=11).

Interventions

For measurement validation, CBG-angle measurements were compared with manual, clinician-obtained angles. To assess motivational effect, the CBG was worn after TKA; on alternating days, it either monitored AROM silently (no feedback) or provided audiovisual feedback about reaching preset range of motion (ROM) goals …


Bs News Jun 2004

Bs News

Building Services Engineering

No abstract provided.


Image Analysis Techniques For The Automated Evaluation Of Subaxial Subluxation In Cervical Spine X-Ray Images, R. Joe Stanley, Santosh Seetharaman, L. Rodney Long, Sameer K. Antani, George R. Thoma, Edward Downey Jun 2004

Image Analysis Techniques For The Automated Evaluation Of Subaxial Subluxation In Cervical Spine X-Ray Images, R. Joe Stanley, Santosh Seetharaman, L. Rodney Long, Sameer K. Antani, George R. Thoma, Edward Downey

Electrical and Computer Engineering Faculty Research & Creative Works

Rheumatoid arthritis is a chronic inflammatory disease affecting synovial joints of the body, especially the hands and feet, spine, knees and hips. For many patients, the cervical spine is associated with rheumatoid arthritis. Subluxation is the abnormal movement of one of the bones that comprise a joint. In this research, image analysis techniques have been investigated for the recognition of cervical spine x-ray images with one or more instances of subaxial subluxation. Receiver operating characteristic curve results are presented, showing potential for subaxial subluxation discrimination on an image-by-image basis.


An In Vitro Evaluation Of Tyrosine Derived Polyarylates And Polycarbonate As Polymeric Scaffold For Human Mesenchymal Stem Cells Osteogenic Differentiation, Manish Suresh Godbole May 2004

An In Vitro Evaluation Of Tyrosine Derived Polyarylates And Polycarbonate As Polymeric Scaffold For Human Mesenchymal Stem Cells Osteogenic Differentiation, Manish Suresh Godbole

Theses

Human mesenchymal stem cells (hMSCs) obtained from the adult bone marrow are multipotential cells that are capable of differentiating along several lineages. They are readily available and abundant source of cells in the field of tissue engineering. For their use in treating certain connective tissue defect or disorders, their success depends at minimum on the use of scaffolds that support differentiation. Therefore , this thesis details a study that systematically evaluated hMSC differentiation on materials that exhibit gradual range in surface properties as a first study for selecting materials as potential scaffolds. Polycarbonates and polyarylates have combinatorial libraries that exhibit …


Characterization Of Electrospun Dlplga Nanofibers For A Drug Delivery System For Intracranial Tumors And Avms, Kimberly A. Griswold May 2004

Characterization Of Electrospun Dlplga Nanofibers For A Drug Delivery System For Intracranial Tumors And Avms, Kimberly A. Griswold

Theses

Electrospinning processes apply electric fields to a polymer solution in order to produce strands of polymer in the nanoscale range. These polymer fibers are manipulated for their porosity, high surface area, fineness and uniformity. In order to create the ideal drug delivery system for intracranial arteriovenous malformations (AVMs) and tumors, D, L poly-(lactice-poly-glycolide) (DLPLGA) nanofibers were electrospun in a tetrahydrofuran (THF) solvent. Three different concentration ratios of DLPLGA, 85/15, 80/20, and 75/25 were analyzed to obtain the prime base for drug annexation. 1 ,3-bis (2-chloroethyl)- 1 -nitrosourea (BCNU) was then codissolved with the DLPLGA nanofibers to form a homogenous solution, …