Digital Commons Network^™

Rational Risk/Benefit Analysis Of Genetically Modified Crops, Stanley P. Kowalski

Law Faculty Scholarship

Safety concerns over the use of molecular biotechnology in the improvement of crops has generated substantial, heated and confusing debates, often driven by ideology and hysterics. Modification of crops is not new, and biotechnology (in its broadest sense) has been used for over a century to accelerate the development of new crops for food, feed and fibre, so as to meet the demands of a growing global community. The introduction of crops developed via molecular biotechnology [Genetically Modified Crops (GMCs)] represents the latest step in this inexorable innovative progression of technology. However, misinformed concern has led to a broad embrace …

Selected Lid Projects In New England, New England Environmental Finance Center

Planning

Examples of low impact development (LID) projects in each state in New England.

Integrating Project-Based Learning Throughout The Undergraduate Engineering Curriculum, Richard N. Savage, Katherine C. Chen, Linda Vanasupa

Materials Engineering

Equipping engineering students with the skills and knowledge required to be successful global engineers in the 21st century is one of the primary objectives of undergraduate educators. Enabling students to practice self-directed learning, to find solutions to design problems that are sustainable and to recognize that they are part of a global community are just of few of our educational goals. Self-directed learning can define an individual’s ability to practice life-long learning. It places the responsibility on the individual to initiate and direct the learning process and can enable an individual to adapt to change. Project-based learning provides the contextual …

2006/07 Research And Development, College Of Engineering And Applied Sciences

Electrical and Computer Engineering Newsletter

• Swarm Behavior
• Expanding Your Horizons @ WMU Engineering
• Design of a Reconfigurable Digital Architecture for Fuzzy Automata
• Rehabilitation Engineering
• Integrated Smart Wireless SAW Sensors and Systems
• Early Detection of Prostate Cancer
• Michigan Space Grant Consortium (MSGC) conference provides research opportunities to WMU students

Benjamin In Paris: Weak Messianism And Memories Of The Oppressed, Jules Simon

Selected Works Temporary Series

No abstract provided.

Remediation Of Rdx- And Hmx-Contaminated Groundwater Using Organic Mulch Permeable Reactive Barriers, Farrukh Ahmad, Stephen P. Schnitker, Charles J. Newell

United States Army: Publications

Organic mulch is a complex organic material that is typically populated with its own consortium of microorganisms. The organisms in mulch breakdown complex organics to soluble carbon, which can then be used by these and other microorganisms as an electron donor for treating RDX and HMX via reductive pathways. A bench-scale treatability study with organic mulch was conducted for the treatment of RDX- and HMX-contaminated groundwater obtained from a plume at the Pueblo Chemical Depot (PCD) in Pueblo, Colorado. The site-specific cleanup criteria of 0.55 ppb RDX and 602 ppb HMX were used as the logical goals of the study. …

Resources: Student Friendly Modeling Materials, Todd R. Kelley, Jared Berrett

Publications

The article presents cost-effective materials for elementary classrooms that allow students to create models. These materials include card stock, clay, cable or zips ties, fasteners and bolts, and commercially manufactured building kits such as LEGOs, Erector Sets, Tinkertoys and K'Nex. In addition, the author asserts the importance of using such materials in promoting student learning of technology and engineering.

Synthesis And Antimalarial Activity Of New Isotebuquine Analogues, Olga V. Miroshnikova, Thomas H. Hudson, Lucia Gerena, Dennis E. Kyle, Ai J. Lin

United States Army: Publications

Amodiaquine (AQ) and tebuquine are 4-aminoquinoline antimalarials with Mannich base side chain and are highly effective against chloroquine (CQ)-resistant strains of Plasmodium falciparum. Clinical use of AQ has been severely restricted due to hepatoxicity and agranulocytosis side effects associated with its long term use. Lysosomal accumulation and bioactivation to generate reactive quinoneimine metabolite are implicated to be the cause of the observed AQ toxicities. To avoid the quinoneimine formation and thus the toxicity, a series of isotebuquine analogues and their N^ω-oxides with hydroxy group meta to the amino rather than in para position of the aniline moiety …

An Electrospray-Based, Ozone-Free Air Purification Technology, Gary Tepper, Royal Kessick, Dmitry Pestov

Mechanical and Nuclear Engineering Publications

A zero-pressure-drop, ozone-free air purification technology is reported. Contaminated air was directed into a chamber containing an array of electrospray wick sources. The electrospray sources produce an aerosol of tiny, electrically charged aqueous droplets.Charge was transferred from the droplets onto polar and polarizable species in the contaminated air stream and the chargedcontaminants were extracted using an electric field and deposited onto a metal surface. Purified air emerged from the other end of the chamber. The very small aqueous electrospray droplets completely evaporate so that the process is essentially dry and no liquid solvent is collected or recirculated. The air purification …

Critical Inquiry Into Urban African American Students' Perceptions Of Engineering, Cameron D. Denson, Zanj K. Avery, John W. Schell

Reports of Center Studies

The purpose of this study was to critically examine the perceptions that African- American high school students have towards engineering. A qualitative research design using criterion sampling and snowballing was used to select seven African-American students from urban high schools to participate in the research. Semi-structured interviews were used to collect data from participants attending urban high schools on the east and west coast. Using Critical Race Theory (CRT) as the theoretical framework, the study was able to produce “emergent themes” from collected data. Findings from this study will help researchers understand how African-American students may perceive the field of …

Young Women’S Perceptions Of Technology And Engineering: Factors Influencing Their Participation In Math, Science And Technology?, Leah C. Roue

Reports of Center Studies

The current number of women in technology and engineering only represents a fraction of today’s workforce. Technological innovation depends on our nation’s best and brightest, representing all segments of our diverse society. Sanders (2005), in talking about women in technology and engineering, stated that women’s lack of participation can only be measured in jobs not filled, problems not solved, and technology not created. Research in the area of how young women view technology will provide insights into how to better encourage and prepare them for careers in technology and engineering.

The purpose of this exploratory study was to examine four …

Position And Orientation Correction For Pipe Profiling Robots, Andrew John Dettmer

Doctoral Dissertations

Sewer pipelines are prevalent, important, valuable, unnoticed, and often in a state of disrepair. Pipeline inspection is essential for effective management of wastewater systems and is now mandated for many municipalities complying with the Governmental Accounting Standards Board Statement 34 and EPA regulations. Pipe inspection robots are routinely used to inspect underground pipelines for cracks, deformations, leaks, blockages and other anomalies to prevent catastrophic failure and to ensure cost effective maintenance and renewal. Most existing pipe inspection robots only collect video footage of pipe condition. Pipe profiling technology has recently been introduced to allow for measurement of the internal coordinate …

Identifying Trends In Underground Coal Mine Incidents Caused By Roof Falls, Cary Cooper

Opportunities for Undergraduate Research Experience Program (OURE)

Current technology and safety practices generally provide today's underground coal miner with a safe workplace in an unpredictable environment. However, incidents still occur and until the number of incidents resulting in injury or loss of life reaches zero, there will always be room for improving methods and technology used by the modern coal miner. This study analyzes underground coal mine incidents caused by roof falls. Information provided by the Mine Safety and Health Administration (MSHA) was analyzed for trends in factors that contribute to roof fall fatalities in underground coal mines. Identification of major contributing factors will allow for a …

Mechanical Characterization Of Spherical Hydrogels: Contact Diameter Measurement, Joshua Bunch

Opportunities for Undergraduate Research Experience Program (OURE)

In an effort to develop new ophthalmic treatments revolving around the ocular lens, the mechanical characteristics of natural ocular lenses and synthetic models must be determined and compared. One mechanical characteristic that is necessary when making comparisons is the variation of contact circle diameter or contact area with varying strains. A method was used in this experiment to measure the varying contact circle diameter of spherical hydrogels at strains up to 15%. This method could be used to estimate the varying contact diameter of other similar materials such as natural ocular lenses if the precision of the method is improved. …

An Investigation Of The Relationship Between Dermal Stresses And Foot Ground Stresses In Diabetic Patients, Zaid M. Hasasneh

ETD Archive

The number of people diagnosed with diabetes in the U.S. has been showing a large increase. It has more than doubled during the period of 1980 to 2002. Approximately 18 million Americans have diabetes today with more than 5.2 million undiagnosed cases. While diabetes is categorized as an endocrine system disorder, some of its known complications are associated to the science of biomechanics. Foot ulcers are caused by vascular deterioration due to diabetes, but also directly related to the natural mechanical forces and loads applied to the feet. Therefore, studying these forces, their locations, distribution and their stresses may be …

Mathematical Model Of Ethanol Metabolism In Liver, Parag Pande

ETD Archive

A lumped mathematical model of liver metabolism is presented to analyze the effect of ethanol on metabolic processes of 24 hr fasted rats. The model is developed in two parts. In the first part individual kinetic models for important regulatory steps in the liver metabolic pathways are developed and in second part transport and mass balance equations in the two well mixed domains: tissue and blood, are developed to calculate intermediate metabolite concentrations and fluxes in response to the changes in ethanol and lactate concentrations in the perfusion medium. Part of the model without ethanol metabolism has been validated and …

U.S. Army Corps Of Engineers Omaha District Monthly Drought Report, April 2007

United States Army Corps of Engineers, Omaha District

Current Conditions

Drought Outlook

Missouri River Region Mountain Snowpack Report

Ft. Peck, Montana

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Garrison, North Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Boat Ramp Information

Noxious Weeds Overview

Cultural Resources Overview

Other Areas of Interest/Concern

Oahe, South Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Mainstem Reservoir Information, Weekly Elevation Comparison 5 MAR 2007 through 26 MAR 2007

Mainstem Reservoir Storage Comparison Water Years 2004, 2005, 2006

Ft. Peck, MT

Garrison, ND

Oahe, SD

U.S. Army Corps Of Engineers Omaha District Monthly Drought Report, July 2007

United States Army Corps of Engineers, Omaha District

Current Conditions

Drought Outlook

Missouri River Region Mountain Snowpack Report

Ft. Peck, Montana

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Garrison, North Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Boat Ramp Information

Noxious Weeds Overview

Cultural Resources Overview

Other Areas of Interest/Concern

Oahe, South Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Mainstem Reservoir Information, Weekly Elevation Comparison 4 JUNE 2007 through 25 JUNE 2007

Mainstem Reservoir Storage Comparison Water Years 2004, 2005, 2006

Ft. Peck, MT

Garrison, ND

Oahe, SD

U.S. Army Corps Of Engineers Omaha District Monthly Drought Report, March 2007

United States Army Corps of Engineers, Omaha District

Current Conditions

Drought Outlook

Missouri River Region Mountain Snowpack Report

Ft. Peck, Montana

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Garrison, North Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Boat Ramp Information

Noxious Weeds Overview

Cultural Resources Overview

Other Areas of Interest/Concern

Oahe, South Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Mainstem Reservoir Information, Weekly Elevation Comparison 5 FEB 2007 through 26 FEB 2007

Mainstem Reservoir Storage Comparison Water Years 2004, 2005, 2006

Ft. Peck, MT

Garrison, ND

Oahe, SD

U.S. Army Corps Of Engineers Omaha District Monthly Drought Report, September 2007

United States Army Corps of Engineers, Omaha District

Current Conditions

Drought Outlook

Ft. Peck, Montana

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Garrison, North Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Boat Ramp Information

Noxious Weeds Overview

Cultural Resources Overview

Other Areas of Interest/Concern

Oahe, South Dakota

Reservoir Elevation Overview

Water Intake Overview

Access Overview

Noxious Weeds Overview

Cultural Resources Overview

Mainstem Reservoir Information, Weekly Elevation Comparison 6 AUGUST 2007 through 27 AUGUST 2007

Mainstem Reservoir Storage Comparison Water Years 2004, 2005, 2006, 2007

Ft. Peck, MT

Garrison, ND

Oahe, SD

Army Research Needs For Automated Neuropsychological Tests: Monitoring Soldier Health And Performance Status, Karl E. Friedl, Stephen J. Grate, Susan P. Proctor, James W. Ness, Brian J. Lukey, Robert L. Kane

United States Army: Publications

Information on the mental status of soldiers operating at the limits of human tolerance will be vital to their management in future deployments; it may also allow earlier intervention for conditions such as undiagnosed Gulf War illnesses and Parkinson’s Disease. The Army needs a parsimonious set of neuropsychological tests that reliably identify subtle changes for: (1) early detection of individual health and military performance impairments and (2) management of occupational and deployment health risks. Testing must characterize cognitive lapses in healthy individuals faced with relevant operational stressors (i.e., anxiety, information overload, thermal strain, hypoxia, fatigue, head impact, chemical or radiation …

A Refined Pharmacophore Identifies Potent 4-Amino-7-Chloroquinoline-Based Inhibitors Of The Botulinum Neurotoxin Serotype A Metalloprotease, James C. Burnett, Dejan Opsenica, Kamaraj Sriraghavan, Rekha G. Panchal, Gordon Ruthel, Ann R. Hermone, Tam L. Nguyen, Tara A. Kenny, Douglas J. Lane, Connor F. Mcgrath, James J. Schmidt, Jonathan L. Vennerstrom, Rick Gussio, Bogdan A. Solaja, Sina Bavari

United States Army: Publications

We previously identified structurally diverse small molecule (non-peptidic) inhibitors (SMNPIs) of the botulinum neurotoxin serotype A (BoNT/A) light chain (LC). Of these, several (including antimalarial drugs) contained a 4-amino-7-chloroquinoline (ACQ) substructure and a separate positive ionizable amine component. The same antimalarials have also been found to interfere with BoNT/A translocation into neurons, via pH elevation of the toxin-mediated endosome. Thus, this structural class of small molecules may serve as dual-function BoNT/A inhibitors. In this study, we used a refined pharmacophore for BoNT/A LC inhibition to identify four new, potent inhibitors of this structural class (IC50’s ranged from 3.2 to 17 …

An In Vitro Comparative Study On The Reactivation Of Nerve Agent-Inhibited Guinea Pig And Human Acetylcholinesterases By Oximes, Chunyuan Luo, Min Tong, Nageswararao Chilukuri, Karen Brecht, Donald M. Maxwell, Ashima Saxena

United States Army: Publications

The reactivation of nerve agent-inhibited acetylcholinesterase (AChE) by oxime is the most important step in the treatment of nerve agent poisoning. Since the evaluation of nerve agent antidotes cannot be conducted in humans, results from animal experiments are extrapolated to humans. Guinea pig is one of the animal models that is frequently used for conducting nerve agent antidote evaluations. Several investigations have demonstrated that the efficacy of an oxime primarily depends on its ability to reactivate nerve agent-inhibited AChE. If the in Vitro oxime reactivation of nerve agent-inhibited animal AChE is similar to that of human AChE, it is likely …

United States Air Force Posture Statement 2007, U.S. Air Force

United States Air Force: Publications

Our 2007 Posture Statement articulates the major elements required to fulfill our mission. It reaffirms our commitment to focus our energies on the Global War on Terror; to develop and care for our Airmen and their families; and to recapitalize and modernize our aging aircraft, spacecraft and equipment.

The Complete Management Of Extremity Vascular Injury In A Local Population: A Wartime Report From The 332nd Expeditionary Medical Group/Air Force Theater Hospital, Balad Air Base, Iraq, Michael A. Peck, W. Darrin Clouse, Mitchell W. Cox, Andrew N. Bowser, Jonathan L. Eliason, Donald H. Jenkins, David L. Smith, Todd E. Rasmussen

United States Air Force: Publications

Background: Although the management of vascular injury in coalition forces during Operation Iraqi Freedom has been described, there are no reports on the in-theater treatment of wartime vascular injury in the local population. This study reports the complete management of extremity vascular injury in a local wartime population and illustrates the unique aspects of this cohort and management strategy.

Methods: From September 1, 2004, to August 31, 2006, all vascular injuries treated at the Air Force Theater Hospital (AFTH) in Balad, Iraq, were registered. Those in non-coalition troops were identified and retrospectively reviewed.

Results: During the study …

Impact Of Phlebotomine Sand Flies On U.S. Military Operations At Tallil Air Base, Iraq: 3. Evaluation Of Surveillance Devices For The Collection Of Adult Sand Flies, Douglas A. Burkett, Ronald Knight, James A. Dennett, Van Sherwood, Edgar Rowton, Russell E. Coleman

United States Air Force: Publications

We evaluated the effectiveness of commercially available light traps and sticky traps baited with chemical light sticks for the collection of phlebotomine sand flies. Evaluations were conducted at Tallil Air Base, Iraq, in 2003. In an initial study, a Centers for Disease Control and Prevention (CDC)-style trap with UV bulb collected significantly more sand flies than did an up-draft CDC trap, a standard down-draft CDC trap (STD-CDC), or a sticky strap with a green chemical light stick. In a subsequent study, we found that the addition of chemical light sticks to sticky traps resulted in a significant increase in the …

Cation Exchange Reactions Controlling Desorption Of 90sr2+ From Coarse-Grained Contaminated Sediments At The Hanford Site, Washington, James Mckinley, John M. Zachara, Steven Smith, Chongxuan Liu

United States Department of Energy: Publications

Nuclear waste that bore ⁹⁰Sr²⁺ was accidentally leaked into the vadose zone at the Hanford site, and was immobilized at relatively shallow depths in sediments containing little apparent clay or silt-sized components. Sr²⁺, ⁹⁰Sr²⁺, Mg2+, and Ca²⁺ was desorbed and total inorganic carbon concentration was monitored during the equilibration of this sediment with varying concentrations of Na⁺, Ca²⁺. A cation exchange model previously developed for similar sediments was applied to these results as a predictor of final solution compositions. The model included binary exchange reactions for the four …

Geochemical Processes Controlling Migration Of Tank Wastes In Hanford’S Vadose Zone, John M. Zachara, Jeff Serne, Mark Freshley, Fred Mann, Frank Anderson, Marcus Wood, Tom Jones, Dave Myers

United States Department of Energy: Publications

Nuclear wastes from Hanford’s processing for separation of plutonium are stored in massive, buried, single-shell tanks in 18 tank farms. These so-called tank wastes were initially thermally hot because of radioactive decay, and many exhibited extreme chemical character in terms of pH, salinity, and radionuclide concentration. At present, 67 of the 149 single shell tanks are suspected to have released over 1.9 million L of tank waste to the vadose zone, with most leak events occurring between 1950 and 1975. Boreholes have been placed through the largest vadose zone plumes to define the extent of contaminant migration and to develop …

Valuing Water Quality Improvements In The United States Using Meta-Analysis: Is The Glass Half-Full Or Half-Empty For National Policy Analysis?, George Van Houtven, John Powers, Subhrendu K. Pattanayak

United States Environmental Protection Agency: Publications

The literature estimating the economic value for water quality changes has grown considerably over the last 30 years, resulting in an expanded pool of information potentially available to support national and regional policy analysis. Using 131 willingness to pay estimates from 18 studies that use a similar definition of water quality, we performed a meta-regression analysis and found mixed results. We find that WTP varies in systematic and expected ways with respect to factors such as the size of the water quality changes, average household income, and use/nonuse characteristics of respondents. As a whole, we conclude that our metaregression results …

Analysis And Prediction Of Effectiveness For Residential Hvac Ductwork, Jinson J. Erinjeri

Doctoral Dissertations

An analysis of residential HVAC ductwork has been performed. Ductwork in 55 homes in Northern Louisiana was tested to determine duct leakage by means of using various measurement techniques to determine the differences between the existing methods as well as the revised method developed in this project referred to as Generalized Subtraction Correction Algorithm (GSCA). A protocol to measure and estimate return leaks at operating pressure was developed. The weighted average return leakage for the homes sampled was determined to be 115 cfm at operating pressure whereas the weighted average duct leakage was determined to be 348 cfm at 25 …