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Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam

Master's Theses

A poroelastic finite element model of a heterogeneous articular cartilage disc was

created to examine the tissue response to low amplitude (± 2% strain), low

frequency (0.1 Hz) dynamic unconfined compression (UCC). A strong correlation

has been made between the relative fluid velocity and stimulation of

glycosaminoglycan synthesis. A contour plot of the model shows the relative fluid

velocity during compression exceeds a trigger value of 0.25 μm/s at the radial

periphery. Dynamic UCC biochemical results have also reported a higher

glycosaminoglycan content in this region versus that of day 0 specimens. Fluid

velocity was also found not to be …

A Pmma Conductivity Pretreatment Microfluidics Device For The Optimization Of Electrokinetic Manipulations, Cameron Paul Purcell

Master's Theses

This project encompasses the design and development of a pretreatment microfluidic device for samples of physiological conductivity, namely a saline solution. The conductivity was reduced through the combination of dilution and ion removal using electric fields to enable downstream electro kinetic manipulations. The two major parts of this project include (1) designing a pretreatment protocol to reduce the conductivity of the sample solution to an acceptable level and (2) designing /fabricating a microchip that will effectively allow aim (1) to be performed on chip.

This project is one of the first to observe the effects of an electric field, used …

Value Landscape Engineering: Identifying Costs, Water Use, Labor, And Impacts To Support Landscape Choice., Kelly Kopp, Larry Rupp, Paul G. Johnson, Roger K. Kjelgren, David E. Rosenberg, Heidi Kratsch

CWEL Publications

We present a spreadsheet model that identifies the costs, water, labor, fertilizer, pesticides, fuel, energy, carbon emissions, and particulates required of and generated by a user-specified residential or commercial landscape over its economic life. This life includes site preparation, materials purchase, installation, annual maintenance and replacing landscape features that wear out or die. Users provide a variety of site-descriptive information and the model queries an extensive database of landscape data to calculate costs, required inputs, and impacts. We verified model results against observations of water, labor, fertilizer, and fuel use over eight years at three landscapes in the Salt Lake …

Development Of An In-Vitro Hyperglycemic Tissue Engineered Blood Vessel Mimic, Brian C. Wong

Biomedical Engineering

No abstract provided.

Characterisation, Modelling And Simulation Of Flexible Polyurethane Foam, Conor Briody, Barry Duignan, Stephen Jerrams

Conference Papers

Flexible polyurethane foam is an open-celled polymeric material that exhibits strain rate and temperature effects. It has found various applications in areas including the packaging, medical, sports, aerospace and aeronautical industries. Polyurethane foam is ubiquitous in seating applications and finds particular use in specialised wheelchair seating where customised seating solutions are required which can provide proper comfort and support without the risk of developing pressure ulcers. Proper seating design is critical for users if this problem is to be avoided, but a lack of quantitative knowledge of this material’s behaviour has limited its effectiveness. The objectives of the work presented …

Study On Weight Loss And Moisture Regain Of Silk Cocoon Shells And Degummed Fibers From African Wild Silkmoths, Addis Teshome, S. K. Raina, F. Vollrath, J. M. Kabaru, J. Onyari, E. K. Nguku

All Peer-Reviewed Publications

A study was conducted to determine weight loss and moisture regain properties of silk cocoon shells, shell layers and degummed fibers of the four African wild silkmoths Anaphe panda, Argema mimosae, Epiphora bauhiniae and Gonometa postica and compare with the industry standard mulberry silkmoth, Bombyx mori. No. significant difference was observed between the moisture regain of the wild silk fibers after degumming. However, there were significant differences in weight loss and moisture regain between cocoon shells as well as shell layers. E. bauhiniae had the lowest weight loss and moisture regain of 23.19 and 5.64%, respectively while G. postica had …

Magnetic Seeding Aggregation To Enhance The Removal Efficiency Of Tio2 Nanoparticles From Water, Ashish Dhananjay Borgaonkar

Dissertations

Engineered nanoparticles, such as titanium dioxide (TiO₂), are important building blocks for the evolution of nanotechnology in industries and commercial products. Ever so increasing use of the engineered nanoparticles is bound to result in a substantial fraction of these nanoparticles ending up in wastewater; or surface water and groundwater, which are sources of intake for drinking water treatment. Removal of these engineered nanoparticles in wastewater and drinking water treatment processes is a very important step towards the protection of environmental and public health as well as protecting water treatment units from fouling and other issues.

Experimental studies showed …

A Study Of The New York / New Jersey Coastal Water : Bio-Optical Characteristics Of The Harbor Estuary And The Effects Of Heavy Metals On Brown Tide Alga Of The Bight, Bin Wang

Dissertations

The New York / New Jersey (NY/NJ) coastal area is one of the most productive regions around the world and a major natural and scenic resource for New York and New Jersey. As a result of excessive nutrient loading in the water, algal blooms have been observed since 1950’s. The NY/NJ coastal area includes the NY/NJ Bight and the NY/NJ Harbor Estuary, and in the former, brown tides (Aureococcus anophagefferens) were first observed in 1985 becoming a more serious water quality problem over the last 25 years. The influence of micronutrients, namely trace metals, on A. anophagefferens that are widespread …

Dissolution Testing Of Prednisone And Salicylic Acid Calibrator Tablets At Different Tablet Locations, Anandhavalavan Arulmozhi

Theses

Dissolution testing is routinely carried out in the pharmaceutical industry to determine the rate of dissolution of solid dosage forms. This test is one of the several tests that pharmaceutical companies typically conduct on oral dosage formulations (e.g., tablets) to determine compliance. The USP Dissolution Testing Apparatus 2 is the most common of the apparatuses listed in the USP. However, it has been shown previously that the dissolution profile of a tablet undergoing dissolution in the USP Dissolution Apparatus 2 can be affected by the tablet location in the apparatus.

In this work, the dissolution rates of both non-disintegrating tablets …

Dissolution Of Disintegrating Solid Dosage Forms In A Modified Dissolution Testing Apparatus 2, Shrutiben Rameshbhai Parekh

Theses

Dissolution tests are routinely carried out in the pharmaceutical industry to determine the dissolution rate of solid dosage forms. Dissolution testing serves as a surrogate for drug bioavailability through in vitro–in vivo correlation (IVIVR), and it additionally helps in guiding the development of new formulations and in assessing lot-to-lot consistency, thus ensuring product quality. The United States Pharmacopoeia (USP) Dissolution Testing Apparatus 2 is the device most commonly used for this purpose. Despite its widespread use, dissolution testing using this apparatus remains susceptible to significant error and test failures. There is documented evidence that this apparatus is sensitive to several …

Transdermal And Transbuccal Delivery Of Lidocaine And Nicotine : Combined Effects Of Iontophoresis And Chemical Enhancers, Ran Wei

Theses

This study focused on the effects of iontophoresis and chemical enhancers on drug release. The transport of Lidocaine HCl (LHCl) and Nicotine Hydrogen Tartrate (NHT) through the skin and mucosa was evaluated for potential clinical applications. These two potential delivery routes have the advantage of avoiding first-pass effect. Samples were pretreated with enhancer solutions for one hour before the experiments. Passive or 0.3 mA iontophoresis-assisted drug diffusion was conducted for 8 hours to monitor the cumulative amount of drug released. Graphical methods and mathematical optimization techniques were implemented to analyze the data. The effects of chemical enhancers on the delivery …

The Effect Of Dynamic Standing On The Bone Mineral Density Of Non-Ambulatory Children: A Pilot Study, Megan Diane Damcott

Theses

In recent decades, research in osteoporosis has expanded to include the effects of prolonged immobilization on the load-bearing bones of non-ambulatory children. One current therapeutic intervention for this population is a passive standing program, in which the body is fully supported and continuous, stationary loading is applied to the bones, leading to the legs being primarily inactive. This research focused upon the effect of passive standing and a new therapeutic intervention of dynamic standing, a standing therapy in which the body is supported but vertical, reciprocal displacements which mimic the walking gait are applied to the feet, causing the muscles …

Efficient Support Of Consistent Cyclic Search With Read-Copy-Update And Parallel Updates, Jonathan Walpole, Paul E. Mckenney

Computer Science Faculty Publications and Presentations

A method, system and computer program product for supporting concurrent updates to a shared data element group while preserving group integrity on behalf of one or more readers that are concurrently referencing group data elements without using locks or atomic instructions. Two or more updaters may be invoked to generate new group data elements. Each new data element created by the same up dater is assigned a new generation number that is different than a global generation number associated with the data element group and which allows a reader of the data element group to determine whether the new data …

Impacts Of Future Climate Change And Effects Of Biogenic Emissions On Surface Ozone And Particulate Matter Concentrations In The United States, Y. F. Lam, J. S. Fu, S. Wu, L. J. Mickley

Michigan Tech Publications, Part 1

Simulations of present and future average regional ozone and PM 2.5 concentrations over the United States were performed to investigate the potential impacts of global climate change and emissions on regional air quality using CMAQ. Various emissions and climate conditions with different biogenic emissions and domain resolutions were implemented to study the sensitivity of future air quality trends from the impacts of changing biogenic emissions. A comparison of GEOS-Chem and CMAQ was performed to investigate the effect of downscaling on the prediction of future air quality trends. For ozone, the impacts of global climate change are relatively smaller when compared …

Detection Of Acute Promyelocytic Leukemia Pml/Rarî± Fusion Gene Using Graphene Modified Glassy Carbon Electrode, Zhi-Xian Lian, Guang-Xian Zhong, Kun Wang, Ai-Lin Liu, Xin-Hua Lin, Yuan-Zhong Chen

Journal of Electrochemistry

A graphene modified glassy carbon electrode (GCE) was prepared by electrochemical reduction of graphite oxide fixed on the surface of GCE. Then, the amino-group modified probe of acute promyelocytic leukemia (APL) PML/RARα fusion gene fragment was immobilized onto surface of the graphene modified GCE by coupling activating agent. With methylene blue (MB) as a novel electrochemical indicator, artificial APL PML/RARα fusion gene fragment was measured by differential pulse voltammetry (DPV). The result indicated graphene nanomaterial showed good sensitization on the signal of MB. The relationship between the reduction peak current of MB and the concentration of complementary strand was linear …

Ios Mobile Device Forensics: Initial Analysis, Rita M. Barrios, Michael R. Lehrfeld

Annual ADFSL Conference on Digital Forensics, Security and Law

The ability to recover forensic artifacts from mobile devices is proving to be an ever-increasing challenge for investigators. Coupling this with the ubiquity of mobile devices and the increasing complexity and processing power they contain results in a reliance on them by suspects. In investigating Apple’s iOS devices -- namely the iPhone and iPad -- an investigator’s challenges are increased due to the closed nature of the platforms. What is left is an extremely powerful and complex mobile tool that is inexpensive, small, and can be used in suspect activities. Little is known about the internal data structures of the …

The Yin And Yang Actions Of North American Ginseng Root In Modulating The Immune Function Of Macrophages, Chike Godwin Azike, Paul Abrahams Charpentier, Jirui Hou, Hua Pei, Edmund Man King Lui

Physiology and Pharmacology Publications

BACKGROUND: Immuno-modulatory effects of ginseng, including both immuno-stimulatory and immuno-suppressive effects, have been widely reported. This study aims to determine whether the paradoxical immuno-modulatory effect is related to unique phytochemical profiles of different North American (NA) ginseng, namely aqueous (AQ) and alcoholic (ALC) extracts.

METHODS: AQ and ALC extracts were prepared and their immuno-bioactivity were studied in vitro in murine macrophages (Raw 264.7) through measuring the direct stimulatory production of pro-inflammatory mediator and cytokines as well as the suppression of lipopolysaccharide (LPS)-stimulatory response by the two extracts. Gel permeation chromatography was used to fractionate and isolate phytochemicals for characterization of …

Aacsb‐Accredited Schools’ Adoption Of Information Security Curriculum, Linda Lau, Cheryl Davis

Annual ADFSL Conference on Digital Forensics, Security and Law

The need to professionally and successfully conduct computer forensic investigations of incidents has never been greater. This has launched an increasing demand for a skilled computer security workforce (Locasto, et al., 2011). This paper examines the extent to which AACSB-accredited universities located in Virginia, Maryland and Washington, D.C. are working towards providing courses that will meet this demand. The authors conduct an online research of the information security courses and programs offered by the 27 AACSB-accredited business schools in the selected area.

The preliminary investigation revealed that eight of the 27 participating universities did not offer any courses in cybersecurity, …

Backtrack In The Outback - A Preliminary Report On Cyber Security Evaluation Of Organisations In Western Australia, Craig Valli, Andrew Woodward, Peter Hannay

Annual ADFSL Conference on Digital Forensics, Security and Law

The authors were involved in extensive vulnerability assessment and penetration testing of over 15 large organisations across various industry sectors in the Perth CBD. The actual live testing involved a team of five people for approximately a four week period, and was black box testing. The scanning consisted of running network and web vulnerability tools, and in a few cases, exploiting vulnerability to establish validity of the tools. The tools were run in aggressive mode with no attempt made to deceive or avoid detection by IDS/IPS or firewalls. The aim of the testing was to determine firstly whether these organisations …

Slides: The Costs And Benefits Of Best Management Practices: Insights From The Marcellus Shale, Timothy J. Considine

Best Management Practices (BMPs): What? How? And Why? (May 26)

Presenter: Timothy J. Considine, School of Energy Resources, Department of Economics and Finance, University of Wyoming

15 slides

Slides: Collaborative Planning And Lessons Learned, Matt Sura

Best Management Practices (BMPs): What? How? And Why? (May 26)

Presenter: Matt Sura, University of Colorado Law School

48 slides

The Green, Blue And Grey Water Footprint Of Crops And Derived Crop Products, Mesfin Mekonnen, Arjen Y. Hoekstra

Daugherty Water for Food Global Institute: Faculty Publications

Abstract. This study quantifies the green, blue and grey water footprint of global crop production in a spatially-explicit way for the period 1996–2005. The assessment improves upon earlier research by taking a high-resolution approach, estimating the water footprint of 126 crops at a 5 by 5 arc minute grid. We have used a grid-based dynamic water balance model to calculate crop water use over time, with a time step of one day. The model takes into account the daily soil water balance and climatic conditions for each grid cell. In addition, the water pollution associated with the use of nitrogen …

Optimizing High Volume Traffic Surges Using Discrete Event Simulation, Claire L. Johnson

Doctoral Dissertations and Master's Theses

The purpose of this applied research study is to determine the fidelity of a discrete event simulation tool called the Evacuation Simulation Prediction Tool (ESP) in predicting transit times during a high volume surge in traffic flow. The ESP tool was developed for the purpose of predicting and optimizing large-scale evacuations of counties or regions as an aide in emergency and disaster preparedness planning. The goal of the ESP model is to ascertain the balance of traffic flow capacity by managing the human factor events that impinge upon orderly highway travel without immobilizing the travel route. The objective of this …

Hospital Vozandes Del Oriente Wastewater Treatment System Design, James Dykstra, Rachel Koopman, Ben Vander Plas, Sungmin Youn

All Engineering Faculty Research

Shell is a town located in the Eastern foothills of the Ecuadorian Andes approximately 94 miles Southeast of Quito. Hospital Vozandes del Oriente (HVO) is a hospital located in Shell owned and operated by Hoy Cristo Jesús Bendice (HCJB) Global. HCJB is a non-profit mission organization committed to Biblical values and community development principles.

Pure Pastaza, a senior design team from Calvin College, in conjunction with HCJB, has designed a wastewater treatment system for HVO. The design promotes the protection of human and environmental health by providing a sustainable solution to wastewater treatment and sets an example of stewardship to …

The Passive Load-Bearing Capacity Of The Human Lumbar Spine In The Neutral Standing Posture, Shaun B. Jeffs

Theses and Dissertations

The human lumbar spine has been shown to support compressive loads of 1000 N in standing and walking, and up to many thousands of Newtons in strenuous activities such as lifting. The literature presents a number of biomechanical models that seek to replicate the load-carrying capacity of the spine while adhering to physiological constraints. While many of these models provide invaluable insights into the mechanisms governing spinal stability, there is a nearly universal disregard for the magnitude of the muscle forces required in the neutral standing posture. In compliance with constraints on metabolic cost and muscle fatigue, muscle activations in …

A Review Focused On The Psychological Effectiveness Of Tai Chi On Different Populations, Long Zhang, Thomas Lowder, Jian Liu

Computer Sciences and Electrical Engineering Faculty Research

As a popular exercise form, Tai Chi (TC) has been investigated to determine its contributions to an active and healthy lifestyle. There are an increasing number of researchers who focus on exploring the potential physiological and psychological benefits of TC but only a few systematic reviews of these benefits to a variety of populations. The purpose of this paper is to comprehensively evaluate the reported psychological benefits associated with practicing TC. Although many investigators have reported possible psychological benefits of TC for children, young adults, older healthy adults, and for a variety of patient populations, many of the reports suffer …

Determination Of Selected Course Management Systems Advantages And Challenges: A Case Study, Dolruedee Suppacheewa

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Dolruedee Suppacheewa on May 12, 2011

Historical Legacies, Information And Contemporary Water Science And Management, Daniel J. Bain, Jennifer A. S. Arrigo, Mark B. Green, Brian A. Pellerin, Charles J. Vörösmarty

Advanced Science Research Center

Hydrologic science has largely built its understanding of the hydrologic cycle using contemporary data sources (i.e., last 100 years). However, as we try to meet water demand over the next 100 years at scales from local to global, we need to expand our scope and embrace other data that address human activities and the alteration of hydrologic systems. For example, the accumulation of human impacts on water systems requires exploration of incompletely documented eras. When examining these historical periods, basic questions relevant to modern systems arise: (1) How is better information incorporated into water management strategies? (2) Does any point …

Determination Of Time-And Height-Resolved Volcanic Ash Emissions And Their Use For Quantitative Ash Dispersion Modeling: The 2010 Eyjafjallajökull Eruption, A. Stohl, A. J. Prata, S. Eckhardt, L. Clarisse, A. Durant, S. Henne, N. I. Kristiansen, A. Minikin, U. Schumann, P. Seibert, K. Stebel, H. E. Thomas, T. Thorsteinsson, K. Tørseth, B. Weinzierl

Michigan Tech Publications, Part 1

The Aprilg-May, 2010 volcanic eruptions of Eyjafjallajökull, Iceland caused significant economic and social disruption in Europe whilst state of the art measurements and ash dispersion forecasts were heavily criticized by the aviation industry. Here we demonstrate for the first time that large improvements can be made in quantitative predictions of the fate of volcanic ash emissions, by using an inversion scheme that couples a priori source information and the output of a Lagrangian dispersion model with satellite data to estimate the volcanic ash source strength as a function of altitude and time. From the inversion, we obtain a total fine …

How Much Do U.S. University Students Know, And Want To Know, About Sustainability And Green Building? The Findings Of A Survey, And Possible Implications For General Elective Curricula., Jeremy R. Farner

Purdue Polytechnic Masters Theses

Using the survey approach, this investigation examined the attitudes and interest of college students at two universities in different geographic locations within the United States.  Approximately 24,000 students from all disciplines and majors at Weber State University (WSU) in Utah, and 4,000 at Purdue University in Indiana, were invited to participate in a study to determine current knowledge, familiarity, and interest in topics within the sustainability and Green Building educational arena. The goal of this study was to determine what students already know, would like to know, and how much interest there would be in developing …