Digital Commons Network^™

Engineered Multifunctional Drug-Loaded Dendrimer Nanoparticles For Glaucoma: Triple Mechanism Via Antioxidant Activity, Iron Chelation, And Enhanced Ocular Transport, Burhan Ates, Ashish Trital, Vimalin Jeyalatha Mani, Lei Xu, Jonathan Kenlee, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

In this study, we developed multifunctional nanoparticles based on polyamidoamine (PAMAM) dendrimers functionalized with caffeic acid (CA) and poly (ethylene glycol) maleimide (PEGM) for the topical delivery of hydrophobic antiglaucoma drugs brimonidine (BM) and betaxolol (BX). The PAMAM-CA and PAMAM-CA-PEGM conjugates exhibited antioxidant and iron-chelating activities in a dose-dependent manner. BM- and BX-loaded dendrimer nanoparticles produced using a multi-inlet vortex mixer showed uniform spherical morphology (∼80 nm by TEM) and hydrated sizes of ∼135-144 nm by DLS. Both nano formulations demonstrated high cytocompatibility with human corneal epithelial cells and were nonirritant in the HET-CAM assay, with PEGM further improving cytocompatibility. …

Workstation Redesign, Mclean Dowell, Anna Seville, Luz Corral Parra, Farah Talib

Senior Design Project For Engineers

Tellerex is a leading ATM refurbishing and repair company operating from Atlanta, Georgia. Due to its rapid growth, the company is facing challenges pertaining to their parts repair and refurbishing lab. Tellerex aims to fulfill orders by 4:00 pm on the day they are placed, guaranteeing their clients same-day shipping. Orders often build up throughout the day, causing lab technicians to stress, rush through orders, and lose organization.

Tellerex has requested our help regarding one of their repair/refurbishment labs. Our goal is to redesign the lab workspace through human ergonomics and Lean Six-Sigma principles. The company wants us to create …

Spike Timing Depended Plasticity Produces Unsupervised Learning Of Synergistic Muscle Feedback In A Synthetical Neural Network, Mark Allen Pupkiewicz

Dissertations and Theses

This study investigates how type Ia feedback from muscle spindles can be organized into groups representing agonistic muscle pairs through Spike Timing Dependent Plasticity (STDP). A single degree of freedom joint is actuated with four biologically modeled muscles forming two agonistic pairs. In order to emulate the sensory dynamics of biological muscle spindles, sensors in the model record the active length and velocity states of each muscle, the two primary factors eliciting type Ia afferent responses. In biological networks, synapses from Ia sensory neurons frequently activate interneurons representing agonistic muscle sources. This research investigates whether this organization can emerge in …

Philosophy Of Culinary Arts: Reading Truth Through Language And Taste, Devi Dwi Purwanto, Aji Prasetya Wibawa, Syaad Patmanthara

Bulletin of Culinary Art and Hospitality

The development of Natural Language Processing (NLP) technology has transformed the way we analyze and understand culinary arts through a digital approach. NLP enables the transformation of empirical and sensory culinary knowledge into structured data that can be analyzed computationally. This technology opens up opportunities to explore the relationships between ingredients, techniques, and flavors in culinary arts, as well as to represent culinary reality in a more organized form. This study aims to identify how NLP can represent the relationships between ingredients, techniques, and flavors in culinary arts and their impact on the structure of culinary knowledge from an epistemological, …

Space Agriculture: A Comprehensive Systems-Level Review Of Challenges And Opportunities, Hassan Fazayeli, Aaron Lee M. Daigh, Cassandra Palmer, Santosh Pitla, David Jones, Yufeng Ge

Biological Engineering Faculty Publications

As humanity prepares for prolonged space missions and future extraterrestrial settlements, developing reliable and resilient food-production systems is becoming a critical priority. Space agriculture, the cultivation of plants beyond Earth (particularly on the Moon and Mars), faces a constellation of interdependent environmental, biological, and engineering challenges. These include limited solar radiation, elevated ionizing radiation, large thermal variability, non-Earth atmospheric pressures, reduced gravity, regolith substrates with low nutrient-holding capacity, high-CO₂/low-O₂ atmospheres, pervasive dust, constrained water and nutrient availability, altered plant physiology, and the overarching need for closed-loop, resource-efficient systems. These stressors create an exceptionally challenging environment for plant …

Optimizing Xo Throughput At Imerys, Derek Beasley, Brennan Chandler, Baris Erarslan, Cynthia Grogin

Senior Design Project For Engineers

This project is conducted in collaboration with Imerys to optimize the performance of the VSI (Vertical Shaft Impactor) system at their Plant 4 facility, focusing on improving the production of XO, a fine material used in products such as textured coatings, acid neutralization, and water filtration systems. The VSI operates continuously, producing several materials at the Marble Hill, Georgia location, including #1 Chip, #2 Chip, OZ, XO, Z, and 30–50. The main focus of this project is to increase the throughput of XO, as it requires both throughput improvement and product quality consistency to meet growing market demand. Imerys’ quality …

The Safety Kuznets Curve: Context In Occupational Safety, Andy Knickerbocker

ASEM Capstones

2025 ASEM 620 Capstone Project

A Predictive Model For Multi- Week Respiratory Risk From Red Tide On Florida’S Gulf Coast., Elmer S. Ochaeta

Computer Science and Engineering Faculty Publications

Florida’s Gulf Coast red tide (Karenia brevis) can put toxins into the air, making people cough, irritating the throat, and worsening asthma or other breathing problems especially when winds blow from the ocean toward the beach. Right now, most public updates don’t really help with the question people actually ask when planning a weekend or vacation: “Will going to or close to the beach be risky in the next few weeks?”.

In this project, I build a weekly early warning system that estimates respiratory risk for specific beaches and predicts that risk 2 to 4 weeks ahead. The study covers …

An Innovative Hdm Model For Assessing Renewable Heat Energy Resources In Utility Energy Systems, Mark Alan Ryan

Dissertations and Theses

Renewable Heat Energy projects exhibit numerous unique, complex, and often conflicting characteristics, including varying project sizes, diverse energy resources, stakeholder demands, and significant challenges in energy conversion applications. Traditionally, cash flow analysis and return on investment are the most widely recognized metrics for evaluating remote energy projects. However, numerous quantitative and qualitative factors influence the overall performance and success of Renewable Heat Energy System (RHES) projects. A comprehensive approach using advanced tools is essential for assessing the factors and criteria that significantly impact these projects.

This research investigates the key quantitative and qualitative factors that contribute to the successful implementation …

Environmental Risk Assessment Of Textile Waste From Bio-Engineered Fibers In The Fashion Industry, Aayush Pankaj Agarwal, Harshit Soral, Irmak Aktan, Karol Montserrat Gonzalez Saad, Maria Daniela Saa Espinosa, Sheetal Suhas Dhanuka, Yi Yang

Harrisburg University Dissertations and Theses

The global fashion industry generates over 92 million tons of textile waste annually, a figure projected to increase significantly by 2030. Bio-engineered fibers, including bacterial cellulose, mycelium-based leather, and recombinant protein textiles emerge as sustainable alternatives to conventional fibers. Despite their promise, recent evidence suggests that these fibers may pose environmental risks at the end-of-life stage, such as incomplete biodegradation in landfills, microfiber shedding, and chemical leaching from dyes and coatings. The purpose of this study is to examine how these risks are represented through scientific literature, corporate sustainability reports, and policy frameworks, and to identify strategies for integrating risk …

Fuel Factors: Jet A Prices And Charter Operations, Manaal Choudhury, Zoey M. Hicks, Chanho Kang, Brooke Wheeler

Aeronautics Student Publications

The relationship between the average monthly fuel price (IndexMundi, 2025) and Part 135 operations (WingX, 2025) was not statistically significant, r = -.009, p = .95.

3d Printed Portable Automatic Pill Dispenser​, Amber M. Ocasio

Publications and Research

Medication adherence is a major public health concern, particularly among patients with chronic illnesses. Reports from the National Institutes of Health indicate that adherence rates are significantly lower for chronic conditions, with patients taking only ~50% of medications prescribed. Unintentional non-adherence—such as forgetting doses—is more prevalent (62.9%, 47.1%, 46.9%) than intentional non-adherence, and the consequences include medication waste, disease progression, reduced functional abilities, lower quality of life, and increased reliance on medical resources. Because existing automatic pill dispensers cost over $100 on average, they remain inaccessible for many lower-income patients who could benefit from such technology. This project addresses this …

Mental Health And Willingness To Seek Mental Health Aid In Aviation, Andrew Lynch, Giacomo Tropeano, Trenton Paige Plogher, Vivek Sharma, Brooke Wheeler

Aeronautics Student Publications

No relationship was found between aviation student mental health status and willingness to seek mental health aid; there was no difference in willingness to seek help between pilots and non-pilots.

Equity-Aware Natural Hazards Resilience Assessment And Improvement Of Road Networks, Naqib Mashrur

LSU Doctoral Dissertations

As climate change intensifies the frequency and severity of hurricanes, the resulting flood events pose escalating threats to transportation infrastructure and community well-being. This dissertation addresses the intersection of flood resilience, network connectivity, and social equity by integrating principles from network analysis, equity planning, and disaster resilience. The research begins by examining the social dimensions of accessibility loss during hurricane-induced flooding. Spatial and demographic analysis reveals that Native American and Hispanic populations in the case study region experience the most significant reductions in access to essential service facilities, highlighting inequities in systems.

Investigating a region southern Louisiana road network demonstrates …

Developing A Waste-To-Energy Assessment Framework Integrating Engineering And Policy Dimensions Using A Triple Bottom Line Approach, Izech Brian O. Edwin, King Harold A. Recto

Electronics, Computer, and Communications Engineering Faculty Publications

The management of municipal solid waste (MSW) in swiftly urbanizing Philippine cities has emerged as a critical concern in both energy and governance. Dependence on landfills is approaching critical thresholds as disposal sites near saturation, transportation costs escalate, and host communities increasingly resist garbage transfers. In response, this study proposes a comprehensive Waste-to-Energy (WtE) assessment framework that integrates engineering evaluation with policy and stakeholder analysis to support sustainable decision- making.

Using Baguio City as a case study, the framework applies a Triple Bottom Line (TBL) approach to evaluate three waste management scenarios: (1) current landfill-dominated practices, (2) engineered landfill with …

Business Financial Information Systems, Lirie Koraqi, James Jolovski Prof.

International Journal of Business and Technology

An information system is a combination of software, hardware, and telecommunication networks to collect useful data, especially in an organisation. Many businesses use information technology to complete and manage their operations, interact with their consumers, and stay ahead of their competition. Some companies today are completely built on information technology.

Well designed and implemented business information systems should provide the information management and outside parties need to make informed and timely decisions about the operating health of the company. Business considers the need to have information available to assess the profitability of a new product they are selling or their …

Comparative Evaluation Of Microcontrollers For Real-Time Heart Rate Monitoring And Tachycardia/Bradycardia Detection, Arxhend Jetullahu, Luan Mulaku, Saranda Demolli

International Journal of Business and Technology

The growing demand for portable healthcare devices has led to combining microcontrollers with machine learning models to enable real-time health monitoring. It's quite paramount, specifically in the context of identifying irregularities in heart rate, like tachycardia—where the heart races unusually fast—and bradycardia, an instance of a sluggish heartbeat. The neat thing is that this study takes a stab at contrasting the effectiveness among three popular microcontroller types—the ESP32, the Raspberry Pi, and the Arduino Nano 33 BLE Sense—in terms of real-time tracking of heartbeats and spotting any oddities (using, of course, a model developed with some machine learning elements). At …

Unsaturated Fatty Acid Oil-Based Microdroplets: A Promising Novel Class Of Microdroplets, Ramiz S. Alejilat

Seton Hall University Dissertations and Theses (ETDs)

Droplet-based microfluidics has rapidly advanced numerous fields, including chemistry, biology, materials science, medicine, food science, and cosmetics. In these systems, fluorocarbon oil combined with fluorinated surfactants is the preferred medium for fluid encapsulation, offering exceptional stability and biocompatibility essential for sensitive biological and chemical processes. However, growing concerns about the environmental and biological risks associated with fluorinated chemicals have prompted a search for alternatives.

This study is the first to explore the use of unsaturated fatty acids derived from emu oil for microdroplet formation. We characterized droplet formation based on flow rates and the presence non-fluorinated surfactant at a certain …

Artificial Intelligence In Higher Education: Opportunities And Challenges, Maytha Al-Ali, Adam Marks, Jasur Umirzokov, Noura Metawa

Iraqi Journal for Computer Science and Mathematics

While AI is often presented as a panacea for the challenges facing higher education, there is limited empirical evidence supporting its effectiveness in improving student learning and institutional performance. This gap between expectation and reality emphasizes the need for rigorous research, realistic goal-setting, and careful planning to ensure that AI technologies deliver on their promises in higher education. This study contrasts the potential utilization of AI technologies in Higher Education from the literature, against actual utilization in universities. The study also investigates the key barriers of AI implementation in higher education. This study uses a mixed-research methods approach, including case …

Detection Of Breath, Phonation And Cough Sounds Using Sound Feature Vectors And Artificial Neural Networks By Calculating Lung Forced Vital Capacity With Mobile Infrastructures, Edmond Hajrizi

International Journal of Business and Technology

Objective: In this study, it is aimed to calculate the tidal volume capacity with mobile infrastructures and to determine the O2 and CO2 values from breath, phonation and cough sounds with the help of artificial neural networks using voice feature vectors. In addition, it is aimed to develop a method that will enable computation of forced expiratory volume via mobile devices.

Materials and Methods: Since sound disease diagnosis is basically a classification problem, tidal volume classification is considered as a pattern recognition problem. Our automatic O2 and CO2 classification study as a pattern recognition function includes three subcomponents; Identifying and …

The Impact Of Infrastructure Construction And Remodeling Of Cities On Its People' Quality Of Life Miraj District-(Madi-Cairo) As A Geological Heritage Area, Ahmed M.E. Hammad

Mansoura Engineering Journal

Rapid urbanization is increasing globally, the urbanization rate expected to rise to more than 66% by 2050. (According to UN estimates) the increasing rates of urbanization in the world means adding 2.5 billion people to the urban population within a short period. Which necessitates increasing the traffic axes and the rest of the networks in terms of lengths and widths within the existing cities, and with the presence of the population during these works - despite their inevitability - the quality of their urban life is affected socially, naturally and economically. the research monitors these effects and the extent of …

Kinship Infrastructure Design: Evaluating Diversity And Resilience In Emergency Response Systems Through Agent-Based Modeling, Fayruz Maysha

Doctoral Dissertations and Master's Theses

Traditional infrastructure systems are often designed for predictable scenarios, making them vulnerable to disruption when real-world conditions change unexpectedly. This research addresses that limitation by introducing Kinship Infrastructure Design (KID), a bioinspired framework based on the kinship coefficient (Φ). Adapted from studies of genetic relatedness in eusocial insects, the kinship coefficient (Φ) measures similarity and diversity among system components by calculating the degree to which their functional traits—encoded as a synthetic genome—match. This research investigates whether a system design can achieve a “Goldilocks Zone” of functional diversity where systems achieve optimal adaptability and coordination under uncertainty."

Rather than relying on …

Bridging Modalities: Enhancing Multimodal Sentiment Analysis For Social Media Networks, Misbah Ul Hoque

LSU Doctoral Dissertations

Social media platforms like X (formerly Twitter) serve as rich sources of textual and visual information, making multimodal sentiment analysis essential for understanding complex human emotions. This dissertation aims to advance multimodal sentiment analysis by improving the semantic alignment and fusion of textual and visual features, thereby enabling more accurate and context-aware sentiment interpretation of social media content.

To address challenges in multimodal integration, this work proposes two complementary MSA approaches. The first approach introduces a similarity-based multi-layer attention neural network (SiMANN) that enhances modality integration through cosine-based similarity fusion and modality-specific attention to emphasize salient features in text and …

Fabrication And Evaluation Of Large Alumina Crucibles By Vat Photopolymerization Additive Manufacturing For High-Temperature Actinide Chemistry, R. Joey Griffiths, Christy Santoyo, Jean-Baptise Forien, Bradley Childs, Andrew J. Swift, Andrew Cho, Alexander Wilson-Heid, George Ankrah, Devin Rappleye, Aiden A. Martin, Jason Jeffries, Kiel Holliday

Faculty Publications

Additive manufacturing (AM) offers opportunities to advance the design and function of ceramic tooling in high temperature actinide pyrochemistry. In technical ceramics such as alumina, conventional forming techniques often restrict design flexibility and can limit experimental progress. In this study, we investigate the use of vat photopolymerization (VP) with commercial resins to fabricate large-scale alumina crucibles, reaching dimensions up to 125 mm, which is significantly larger than typically reported for dense VP ceramics. Notably, these additively manufactured components are produced using consumer-grade hardware, which limits process control, but offers significant upside in scalability and accessibility. Using microscopy and X-ray computed …

Iso-Detr: A Novel Detection Transformer For Industrial Small Object Detection, Faisal Saeed, Anand Paul

School of Public Health Faculty Publications

Effectively detecting and assessing real-time structural and ecological parameters in contemporary manufacturing environments poses significant challenges, particularly in identifying minute objects within product images. The swift evolution of the industrial sector underscores the necessity for intelligent manufacturing environments to uphold stringent product quality standards. However, accelerating production processes at high speeds heightens the risk of defective product outcomes. This research addresses the challenges inherent in small object detection within industrial contexts, proposing an innovative detection transformer model tailored to modern manufacturing environments. The proposed model integrates a feature-enhanced multi-head self-attention block (FEMSA), merging cross-channel communication network and multiple multi-head self-attention …

Evaluating Kansai Airport's Ppp: Grounded Ambitions, Concession Of Financial, Geotechnical, And Climate Risk, Edmund Cho, Dimitrios V. Siskos

International Journal of Aviation, Aeronautics, and Aerospace

This study critically examines the Kansai Airports Group’s 44-year Public-Private Partnership (PPP) monopoly-type concession encompassing Kansai International (KIX), Osaka Itami (ITM), and Kobe (UKB) airports. The research uses financial analysis, Monte Carlo simulation, and NPV-at-risk modeling to evaluate how Japan’s fixed-term private monopoly model allocates financial, operational, and environmental risks. In 2015, there were significant developments in the promotion of the Private Finance Initiative (PFI) Act. It was revised in 2015; as a result, it finds that the underestimated long-term maintenance liabilities, especially Kansai airport (KIX) foundation subsidence, and lacked flexibility to manage exogenous shocks like COVID-19 and Typhoon Jebi. …

A Transition Framework For Hybrid Tls In Enterprise-Level Systems, William Hadd

Cybersecurity Undergraduate Research Showcase

Enterprises face an immediate need to protect long-lived data against harvest-now, decrypt-later threats while maintaining interoperability across layered systems. With NIST’s first post-quantum standards finalized (ML-KEM, ML-DSA, SLH-DSA) and TLS hybridization drafts defining concrete ECDHE + ML-KEM groups, adoption can begin at the TLS termination layer even before full ecosystem support for post-quantum signatures arrives (NIST, 2024; IETF, 2025). In this paper, we propose an enterprise-oriented transition framework and maturity model for hybrid TLS across email, internal API gateways, and object storage. We specify where to enforce, which hybrid groups to select, and how to prevent silent downgrade with policy …

Photocatalytic Activity Of The Mixed Of Ti/Fe/Mo Oxide Composites For Degradation Of Nitrofurazone, Dilshoda R. Tursunova, Zuhra Ch. Kadirova, Shahlo Sh. Daminova, Kadriya Kh. Gabidullina

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of study is synthesize mixed oxide composites based on titanium dioxide, iron and molybdenum oxides from industrial waste materials and evaluated for their photocatalytic degradation performance of nitrofurazone—a persistent and toxic antibiotic frequently detected in aquatic environments. Various Ti/Mo ratios (T95M5, T87.5M12.5, T75M25, and T50M50) were prepared through thermal treatment at 600 °C and characterized using XRD, UV–Vis and Raman spectroscopy to assess structural and optical properties.XRD and Raman analyses confirmed the presence of anatase-phase TiO₂ and Mo/Fe oxides, with optimal crystallinity and heterojunction formation observed in the T87.5M12.5 composite. UV–Vis spectroscopic studies demonstrated that this composite exhibited …

Fully Integrated Slippage Detection System For Lower Limb Amputees, Christopher E. Miglio

Master's Theses

Lower limb amputees face significant challenges in maintaining a proper prosthetic fit, as improper fit can lead to slippage at the limb-socket interface, resulting in discomfort, pressure sores, and long-term musculoskeletal complications. To address this issue, a fully integrated slippage detection system was developed to monitor an amputee’s daily activities and slippage occurrences to understand their prosthetic fit over time. The system consists of a prosthetic sock embedded with Interlink 406 flexible piezoresistive force-sensing resistors (FSRs). The sock, worn directly on the residual limb, continuously measures pressure at the limb-socket interface. Sensor data from six FSRs is sampled at approximately …

Applicability Of Syntropic Agriculture To A Semi-Arid Continental Climate: Alentejo To New Mexico, Arielle Nathan, Joana Dionisio Msc, João Serra, Joseph Lanning, Cátia Magro Dr.

Journal of Critical Global Issues

Conventional industrial agriculture has detrimental effects on the environment including pollution and overconsumption of water, soil degradation, and biodiversity reduction. An environmentally sustainable future of food production requires alternative methods that limit negative environmental consequences. Syntropic Agriculture (SA) is a promising farming alternative especially for arid systems at risk of desertification. New Mexico, USA, is a semi-arid continental climate in a prolonged period of drought and predicted to experience worsening agricultural conditions including desertification, wildfire intensification, and exacerbated water scarcity. The Alentejo region of Portugal has a Mediterranean climate with similar agricultural challenges. The agroecological transition project, Terra Sintrópica, located …