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Towards A Multimodal Approach For Assessing Adhd Hyperactivity Behaviors, Franceli L. Cibrian, Lauren Min, Vitica Arnold

Engineering Faculty Articles and Research

Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent childhood psychiatric condition that needs an assessment of inattention, hyperactivity, and impulsiveness symptoms. Particularly in young children, hyperactivity-impulsivity stands out as a primary concern. However, those behaviors may or may not be evidenced when a child is in a small room, one-on-one with a single adult. Therefore, Ambient Intelligence technology that supports data collection in a natural setting, paired with expert human decision-making can potentially improve the quality of assessments. In this paper, we conduct a literature review and analysis to align ADHD assessment criteria with potential sensor technologies to collect …

A Comparison Of Polymers By Layer Deposition And Open Molding Additive Processes Through Fused Granulate Fabrication, Alexander Ray Gibson

Theses and Dissertations

Additive manufacturing (AM) continues to offer new possibilities in both production and economics. Various industries have quickly adopted AM to rapidly produce parts that would be difficult or cost prohibitive otherwise. Despite ongoing innovations that expand the technology's capabilities, significant limitations persist. Most AM processes are restricted by materials available, an inability to produce large parts, or by not achieving material deposition speeds and volumes to allow for certain products feasible. In addition, tight tolerances for features and surfaces cannot be produced without substantial post processing. Some of the post-processing techniques can even affect the material properties of the finished …

A Study On Improving The Accuracy And Effectiveness Of Similarity Detection Processes In Text Files Using Nlp Techniques, Noor Abdulmuttaleb Jaafar

Al-Esraa University College Journal for Engineering Sciences

The rapid expansion of the Internet has revolutionized access to information, especially in the area of unstructured data, most of which consists of textual content. While instant access to information brings many advantages, it has also given rise to a prevalent problem – plagiarism. Copying and reusing materials without proper permission poses a significant threat to academic integrity and integrity. Rates of plagiarism, especially in academic and scientific publications, have risen with the advent of the Internet, reaching alarming levels, such as 60% in student projects. This study examines the proposed model that includes computation of similarity using cosine coefficients, …

Mems 411: Timed Mosquito Egg Container, Daniel Nordquist, Preston Gee, Stephanos Mavrommatis

Mechanical Engineering Design Project Class

To aid in the war against mosquitoes, PHD candidate Lauren Johnson tasked this groups with developing a device to help study egg laying patterns. The goal is to create a device that can cut off access to tea water (an attractive breeding site) at specified time intervals in order to observe the effects of daylight and temperatures on mosquito egg laying behavior.

Mems 411: The Ez-Push Fsae E-Assisted Pushbar, Ian Snider, Hunter Tate, Erik Lillegard, Maxwell Wrasman

Mechanical Engineering Design Project Class

WashU Racing needs a device that will help them transport their Formula SAE car to and from their garage/paddock during events and testing when the car is unable to move under its own power. Pushing the car is very exhausting and requires at least 2 pairs of people, rotating in and out, to push the car. An electronically assisted push bar would only require two people to push the car and wouldn't experience exhaustion due to pushing the car. This device will function similarly to a shopping cart tug while also functioning as a rear jack for the vehicle that …

Mems 411: Dbf Wind Tunnel, Jeremy Choh, Stefan Hester, David Howard, Yang Yang

Mechanical Engineering Design Project Class

Design, Build, Fly (DBF) is a student-run engineering team at Washington University in St. Louis (WUSTL) that designs aircraft for flight competitions. Before assembling the final product, DBF runs numerous simulations on prototypes to understand the effects of drag and lift on the designed shape. The lift and drag parameters are important to aircraft design, as DBF hopes to optimize flight performance during competitions. However, simulations require computational power, are theoretical at best, and may inaccurately represent real-life situations. Preferably, DBF can use physical testing that captures prototype performance with more qualitative details.

Senior Design Group Z approaches DBF's needs …

Tensile Strain Validation Of Welded Wire Reinforcement, Alvaro Montes

Theses and Dissertations

There have been historical concerns regarding the ductility of welded wire reinforcement (WWR). Recent changes in ACI 318-19 now require all grades of A615 and Grade 100 A706 nonprestressed steel reinforcement to have a ratio of tensile strength to yield strength greater than 1.10 and 1.17 respectively. Although this code requirement does not currently apply to WWR, this preemptive study investigated the current state of the art of WWR manufactured in North America in preparation for such a possibility. This project included the tensile-testing of approximately 365 WWR material specimens of various cross-sectional sizes to determine the ratio of tensile-to-yield …

Hidden Markov Model For Identifying Local Variants In Human Genomes Using Simulated Data, Scott Mccallum

Electronic Theses and Dissertations

Identifying adaptive mutations in genetic data is challenging due to the low frequency of occurrence of such events, and because signatures of selection are intertwined with the footprints of various other evolutionary forces that shape our genomes. Even when a larger region appears to be under selection, genomic sites that are linked to adaptive mutations have similar statistical signals, and thus can obfuscate the identification of the actual adaptive mutation. The new method described here uses a Hidden Markov Model that allows for classification of neutral, linked, and sweep (adaptive mutation) genomic sites. This model is general and can be …

Investigating Catalytic Conversion Of Lignin To Valuable Products, Jialiang Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Lignin is a complex, random, and heterogeneous biopolymer in lignocellulosic biomass. It has significant potential for conversion into valuable chemicals and fuels. However, its natural recalcitrant structure has made selective depolymerization challenging. This dissertation presents a detailed investigation into the mechanisms of lignin disassembly and structural evolution under various catalytic and solvent conditions. The research spans three key studies. In Chapter 2, operando magic-angle spinning (MAS) solid-state nuclear magnetic resonance (NMR) spectroscopy was employed to study reaction pathways and kinetics of lignin model polymers during catalytic hydrogenolysis. We used a Ni-Al2O3 catalyst in methanol under high temperature and pressure, and …

Investigating Catalytic Conversion Of Lignin To Valuable Products, Jialiang Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Lignin is a complex, random, and heterogeneous biopolymer in lignocellulosic biomass. It has significant potential for conversion into valuable chemicals and fuels. However, its natural recalcitrant structure has made selective depolymerization challenging. This dissertation presents a detailed investigation into the mechanisms of lignin disassembly and structural evolution under various catalytic and solvent conditions. The research spans three key studies. In Chapter 2, operando magic-angle spinning (MAS) solid-state nuclear magnetic resonance (NMR) spectroscopy was employed to study reaction pathways and kinetics of lignin model polymers during catalytic hydrogenolysis. We used a Ni-Al2O3 catalyst in methanol under high temperature and pressure, and …

Pan-Cancer Analysis Of Rna Dysregulation, Somatic Mutations, And Matrix Stiffness Using Bioinformatics Approaches, Gongyu Tang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cancer is a complex disease driven by genetic mutations, epigenetic modifications, and alterations in the tumor microenvironment. Understanding these intricate molecular mechanisms is crucial for advancing cancer diagnosis, prognosis, and treatment. RNA sequencing (RNA-seq) has emerged as a powerful tool to study cancer by providing comprehensive insights into gene expression, alternative splicing, and mutations at the transcriptome level. This dissertation leverages RNA-seq data to explore different dimensions of cancer biology through multi-omics integration and computational approaches. The research is divided into three main projects. First, I developed OncoDB, an interactive database to analyze gene expression, methylation patterns, and viral interactions …

Discrete Element Method For Mining Industrial Applications: Solving The Clumping Problem Caused By Bulk Cohesive Particles In An Iron Ore Beneficiation Process, Shuang Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

The discrete element method (DEM) is a widely used numerical approach for simulating and analyzing the behavior of granular materials in various applications. This research focuses on the iron ore beneficiation process, addressing the clumping issue in cohesive iron ores from existing crushing processes through a novel double-layered disperser design. The significance of this study lies in its potential to enhance the efficiency of the existing crushing phase and improve the linkage to subsequent purification stages that target smaller-sized iron ore pellets, thereby enhancing the overall efficiency of the ore beneficiation process and achieving significant energy savings. This research adopts …

Pan-Cancer Analysis Of Rna Dysregulation, Somatic Mutations, And Matrix Stiffness Using Bioinformatics Approaches, Gongyu Tang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cancer is a complex disease driven by genetic mutations, epigenetic modifications, and alterations in the tumor microenvironment. Understanding these intricate molecular mechanisms is crucial for advancing cancer diagnosis, prognosis, and treatment. RNA sequencing (RNA-seq) has emerged as a powerful tool to study cancer by providing comprehensive insights into gene expression, alternative splicing, and mutations at the transcriptome level. This dissertation leverages RNA-seq data to explore different dimensions of cancer biology through multi-omics integration and computational approaches. The research is divided into three main projects. First, I developed OncoDB, an interactive database to analyze gene expression, methylation patterns, and viral interactions …

Discrete Element Method For Mining Industrial Applications: Solving The Clumping Problem Caused By Bulk Cohesive Particles In An Iron Ore Beneficiation Process, Shuang Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

The discrete element method (DEM) is a widely used numerical approach for simulating and analyzing the behavior of granular materials in various applications. This research focuses on the iron ore beneficiation process, addressing the clumping issue in cohesive iron ores from existing crushing processes through a novel double-layered disperser design. The significance of this study lies in its potential to enhance the efficiency of the existing crushing phase and improve the linkage to subsequent purification stages that target smaller-sized iron ore pellets, thereby enhancing the overall efficiency of the ore beneficiation process and achieving significant energy savings. This research adopts …

A Comprehensive Usability And Economic Analysis Of Heat-Related Wearable Technologies: Applications To Occupational Health, Ryan T. Cannady

Theses & Dissertations

The purpose of this research was to analyze the usability and economic considerations of real-time wearable technologies that are implemented in occupational settings to assess risk of heat stress and heat strain. The study population included current agriculture workers and Department of Energy (DOE), Environmental Management (EM) contractors. We employed a mixed-methods approach to comprehensively analyze the usability and economic considerations of heat-related technologies. Specifically, our approach assessed three distinct aspects the applications of these technologies in occupational settings to comprehensively address our research objective: (1) worker perceptions of heat-related wearable technologies, (2) field-based assessment of these heat-related wearable technologies, …

Fail-Safe Logic Design Strategies Within Modern Fpga Architectures, Priya A. Bhakta

Electrical and Computer Engineering ETDs

Field Programmable Gate Arrays (FPGAs) are vulnerable to radiation-induced single event upsets (SEUs) and fault injection attacks, requiring the use of redundancy techniques such as fail-safe computing. Fail-safe computing refers to computing systems that revert to a non-operational safe state when a fault occurs. This work investigates circuit-level techniques and implements fail-safe computing processes as mitigation for SEUs and fault injection attacks on FPGAs. The analysis reveals vulnerabilities that exist in FPGAs over those in application-specific integrated circuits (ASIC); thus, requiring a more elaborate network of redundant circuits and checking logic. The reconfiguration capability of FPGAs adds complexity to fail-safe …

Post-Processing National Water Model Long-Range Forecasts With Random Forest Regression In The Cloud To Improve Forecast Accuracy For Decision-Makers And Water Managers, Jacob Matthew Anderson

Theses and Dissertations

Post-processing bias correction of streamflow forecasts can be useful in the hydrologic modeling workflow to fine-tune forecasts for operations, water management, and decision-making. Hydrologic model runoff simulations include errors, uncertainties, and biases, leading to less accuracy and precision for applications in real-world scenarios. We used random forest regression to correct biases and errors in streamflow predictions from the U.S. National Water Model (NWM) long-range streamflow forecasts, considering U.S. Geological Survey (USGS) gauge station measurements as a proxy for true streamflow. We used other features in model training, including watershed characteristics, time fraction of year, and lagged streamflow values, to help …

Local Food System Planning On Multiple Governance Scales: A Grounded Theory Analysis, Decker Ure

Theses and Dissertations

Local food systems (LFS) comprise the people, policies, infrastructure and practices of food production, distribution, and consumption in localized areas. LFS are becoming an increasingly important part of urban sustainable development and have recently gained significant traction in the urban planning and sustainable community spheres. Worldwide shocks to global food systems such as the COVID-19 pandemic and the Ukraine-Russia war have further elevated global interest in LFS, bringing local food to the forefront of many communities as they try to insulate themselves and their food supply from future risk. However, despite this growing interest in and policy momentum for local …

The Coalition Development Of Allied Close Air Support Doctrine During World War Ii, David S. Stieghan

Doctoral Dissertations and Projects

This research aims to discover how the American and British air forces worked collaboratively to provide ground support to their armies in Europe during World War II. While the official histories and scholars of the two countries concentrate on their unique national efforts, they analyze little of their cooperative efforts. By examining primary and secondary research sources to discover the experiments, doctrine development, and combat experience of both air forces, an understanding emerges that both nations combined their efforts in World War II in separate directions until beginning to work together on planning for the D-Day invasion.

By discovering the …

Kinetic Modeling Of Bacteria Removal From Suspensions By Magnetic Nanoparticle Capture And Magnetic Separation, Bowen J. Houser

Theses and Dissertations

This thesis investigates the kinetic modeling of bacteria removal from suspensions using magnetic nanoparticle (MNP) capture and magnetic separation. Functionalized magnetic nanoparticles, especially those coated with polydopamine (pDA), were employed to bind with various bacterial species in phosphate-buffered saline (PBS), apple juice, whole blood, and its components. By analyzing the capture efficiency and kinetics of capture across different bacterial species and mediums, we developed mathematical models describing the capture kinetics of bacteria by the pDA-MNPs. Experimental results demonstrated that pDA-coated MNPs achieved high capture efficiency with certain Gram-positive species like Staphylococcus aureus, and one Gram-negative species, Neisseria perflava; however, capture …

Harnessing Extrinsic Dissipation To Enhance The Toughness Of Composites And Composite Joints: A State-Of-The-Art Review Of Recent Advances, Gilles Lubineau, Marco Alfano, Ran Tao, Ahmed Wagih, Arief Yudhanto, Xiaole Li, Khaled Almuhammadi, Mjed Hashem, Ping Hu, Hassan A. Mahmoud, Fatih Oz

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Interfaces play a critical role in modern structures, where integrating multiple materials and components is essential to achieve specific functions. Enhancing the mechanical performance of these interfaces, particularly their resistance to delamination, is essential to enable extremely lightweight designs and improve energy efficiency. Improving toughness (or increasing energy dissipation during delamination) has traditionally involved modifying materials to navigate the well-known strength-toughness trade-off. However, a more effective strategy involves promoting non-local or extrinsic energy dissipation. This approach encompasses complex degradation phenomena that extend beyond the crack tip, such as long-range bridging, crack fragmentation, and ligament formation. This work explores this innovative …

A Computational And Mathematical Approach To The Preclinical Development Of Alpha Emitting Radiopharmaceutical Therapies, Abdulaziz Said

McKelvey School of Engineering Graduate Student Theses & Dissertations

Numerous candidate nuclides have been undergoing rigorous preclinical development in the pursuit of novel targeted therapies. Successful development of these drugs relies on the understanding of physiological impacts at the macro and micro scales, in addition to a scalable process for their production. Here, mathematical and computerized approaches have been developed to guide this preclinical development. In this report, two alpha emitting nuclides Pb-212 and Ra-223 are modeled. Radium-223 dichloride citrate a newly approved ion indicated for treatment of bone metastatic castrate resistant prostate cancer, irradiates lesions through targeted uptake in bone at sites of disease. We have undertaken the …

Safety And Optimality Monitors For Learning-Enabled Systems Using Conformal Prediction, Jackson Cox

McKelvey School of Engineering Graduate Student Theses & Dissertations

The use of machine learning to create data-driven plant models and controllers has led to an increased need for safety and optimality monitors for model-based systems. System plant models are subject to uncertainty due to learning constraints such as unseen data and overfitting or physical constraints such as unknown dynamics and noise. This uncertainty is detrimental to safety-critical systems and must be properly regulated. To curb this uncertainty, we create prediction sets using the guarantees provided by Conformal Prediction. With a user-specified high probability, these prediction sets contain the true plant system states for an entire prediction horizon, which we …

Phosphorus Adsorption Capacity Of Volcanic Scoria, Easton Jeffrey Perkins

Theses and Dissertations

Phosphorus (P) pollution in stormwater runoff poses a significant threat to water quality, contributing to eutrophication and ecosystem degradation. This research evaluates the potential of volcanic scoria (VSco), an abundant and cost-effective resource in Utah, USA, to influence P concentrations in urban stormwater systems. Batch adsorption experiments examined the behavior of VSco across three particle sizes—fine (<0.841 mm), medium (0.841–2 mm), and granular (2.38–9.5 mm)—under conditions mimicking stormwater scenarios. The results reveal that fine VSco exhibited higher adsorption efficiency than medium and granular sizes, achieving notable P removal at higher concentrations. However, at lower concentrations, fine VSco showed potential for P release due to desorption of pre-existing P. Medium and granular VSco showed minimal adsorption capacity and, in some cases, acted as P sources, highlighting a dual potential depending on stormwater conditions. Adsorption isotherms indicate that the adsorption behavior of fine VSco aligns with the Langmuir model, with a finite and relatively low adsorption capacity. Calculated distribution coefficient (Kd) values for fine VSco ranged from 0.04 to 0.005 L/g, indicating weak adsorption efficiency compared to materials like activated carbon (1–10 L/g) or soils with moderate adsorption capacity (0.1–0.5 L/g). Loss-on-ignition tests confirmed that VSco’s performance is driven by its physical and chemical properties, particularly its calcium content, rather than organic matter. The study emphasizes caution in applying fine VSco for stormwater remediation due to its potential to release P under typical runoff conditions. However, fine VSco may still be viable in specific scenarios where P levels are higher, such as in stormwater hotspots or localized areas with elevated concentrations, allowing for targeted remediation. The research underscores the need for further testing to refine VSco’s applications, particularly in low-impact development (LID) practices, such as infiltration basins and rain gardens, to effectively manage P levels while supporting ecological and aesthetic goals. These findings contribute to understanding the complex role of VSco in urban stormwater systems, offering insights for sustainable water quality management and nutrient cycling in urban landscapes.

Developing A New Liquefaction Ejecta Prediction Model Considering Soil Properties Of Non-Liquifiable Surface Layers Using New Large Database From The 2012 Emilia Romagna, Italy Earthquakes, Jonah Bradley Dundas

Theses and Dissertations

The presence of a non-liquefied crust overlying a liquefied layer has been found to have a significant effect on sand ejecta and surficial liquefaction damage, as observed by Ishihara (1985). Following the 2010-2011 Canterbury seismic sequence in New Zealand, almost no foundation deformation occurred in areas with liquefaction susceptible soils overlain by at least a 3 meter thick crust [1]. In contrast, the 2012 Emilia-Romagna earthquake in Italy provided surface evidence of liquefaction despite 6+ meter thick crusts. Several researchers have proposed liquefaction prediction models [e.g. LPI [2], Ishihara Curves [3], LSN [4], LPIISH [5] and the methods proposed by …

Predictive Maintenance Analysis Of Turbofan Engine Sensor Data, Stanley A. Melkumian

The Journal of Purdue Undergraduate Research

Predictive maintenance in aviation and aerospace applications is among the most explored problems in machine learning (ML) and artificial intelligence (AI), and datasets such as NASA’s C-MAPPS turbofan engine degradation simulation data have proven invaluable, helping researchers explore numerous questions on engine performance, maintenance, and failure. The purpose of this study was to extend the current research on predicting the remaining useful life (RUL) of engines and their risk classification. Starting with simple yet under-investigated nonlinear survival and random forest models, the analysis implemented eXtreme Gradient Boosting (XGBoost) and long short-term memory (LSTM) from TensorFlow’s Keras library. For both regression …

Assessing Coincidence Of Satellite Acquisitions And Flood Events To Predict Suitability For Flood Map Synthesis, Lyle Dale Prince

Theses and Dissertations

Flooding is a global problem that impacts people, communities, and governments every year. Better understanding of flooding in an area can enable improved emergency response before a flood hits. Flood maps are a crucial tool to translate what for most is an abstract flow, into a more understandable and actionable representation of who and what are at risk. Satellite based flood maps are a useful tool that has potentially global applications. We developed methods to determine which areas are suitable for generating satellite-based synthetic flood maps. For our processes we used Forecasting Inundation Extents using REOF analysis (FIER): a data-driven …

A Comparison Of Rfssw And Rsw For Automotive Manufacturing, Damon Michael Gale

Theses and Dissertations

Historically, automotive body panels have been made of steel and joined by a process called resistance spot welding (RSW). However, in efforts to reduce vehicle weight to improve the energy efficiency of the vehicle, automotive manufactures have begun substituting aluminum in place of steel. While aluminum can be joined with RSW, a myriad of challenges arise from doing so. These challenges result in less consistent weld quality and accelerated electrode wear. Refill friction stir spot welding (RFSSW) is an emerging joining technology that could replace RSW as it is believed to be capable of creating superior joints in thin sheet …

Site Amplification In The Salt Lake Valley, Utah, During The 2020 Magna Earthquake, Blair A. Hanson

Theses and Dissertations

Site amplification in the Salt Lake Valley, Utah, has been a focus for both geologists and engineers due to its complex geology and seismic vulnerability. This study utilizes data from the 2020 Magna Earthquake to analyze site amplification from previously unavailable strong ground motion data. Ground motion data from the University of Utah Regional Seismic Network and the National Strong Motion Project, combined with extensive soil profiles, was analyzed using the program DEEPSOIL. The study compares computed motions with measured motions, revealing differences in site amplification across the Salt Lake Valley. Notably, the highest amplification was observed at longer periods …

Discharge-To-Water Level Conversion Using Monthly Duration Curves (Dwl-Mdc): Enhancing The Utility Of The Geoglows Ecmwf Hydrological Model, Darlly Judith Rojas Lesmes

Theses and Dissertations

Flood early warning systems are crucial for disaster risk reduction strategies, enabling communities to take timely action against threats. However, the effectiveness of these systems depends on accurate and timely hydrological data, particularly river discharge and water level measurements. Unfortunately, many regions, face significant challenges in obtaining hydrological data, especially discharge data due to outdated rating curves, high equipment costs, and logistical constraints. Water level measurements, by contrast, offer reduced uncertainty and are often more accessible, providing an alternative for hydrological modeling in data-scarce regions. To address these limitations, we developed and validated the Discharge-to-Water Level Conversion Using Monthly Duration …