Digital Commons Network^™

Modeling And Development Of A Cellular Micro-Kernel, K. Balaji

Masters Theses

A novel cellular load distribution strategy was designed and implemented on transputers by Dr. Richard Taylor and Dr. Don Goodeve at the University of York, United Kingdom. Based upon the above proposed strategy, a statistical model was developed using the Cellular Automata Theory. The theoretical model drives the implementation process of the cellular micro-kernel on the nCUBE 2S system. The load distribution and the performance characteristics for snake and L type transmission modes, and for uniform and non-uniform distribution of destination processors of the micro-kernel has been measured and compared with our theoretical model. The results show good agreement between …

Modeling The Fate Of Volatile Organic Compounds In Wastewater Treatment Facilities; Implementation Of Volatilization Models In Envirocad, Vinita Chhahira

Theses

The 1990 Clean Air Act Amendments have identified wastewater treatment facilities as a major source of volatile organic compound (VOC) emissions. VOCs present in wastewater discharges affect the quality of receiving waters, while emissions to the air affect downwind populations. The primary mechanisms involved in VOC removal from a wastewater treatment facility are volatilization and stripping, biodegradation, and sorption to either suspended or biological solids. Although many models have been developed to predict the fate of VOCs in wastewater treatment facilities, no model completely predicts emissions for an entire wastewater treatment facility. The focus of this work is to incorporate …

Hydrodynamic And Water Quality Modeling Of The Whippany River, John E. Krohn

Theses

The Whippany River is located in northern New Jersey and is a major tributary to the Passaic River System. This waterway accepts a wide variety of wastes from the diverse communities within its watershed. These wastes contribute to a rather complex network of biological, chemical and physical interactions.

The purpose of this study is to develop a water quality model using QUAL2E. This model will be used as a tool to simulate the complex interactions that take place within the river system. The river must he considered from physical, biological and chemical perspectives. A successful model can determine current water …

Effects Of Ergonomic Worksite Changes On Risks For Cumulative Trauma Disorders Of The Upper Body In An Assembly And Press Operation Job, David B. Mahone

Theses

Cumulative trauma of the upper body is associated with a variety of individual and job factors. An effort to optimize the human-hardware interface to minimize cumulative trauma is favored. Workers in a set of jobs had complained about hand/wrist and shoulder discomfort. One job was selected for testing alternate machine controls and worksite layout. Electromyography was used to test muscle activity, and photogoniometry was used to measure posture.

For the group of ten worker-subjects, statistically significant decreases in hand/wrist and shoulder muscle activity were found. A marginal, but significant increase in neck muscle activity was also found. When one subject …

A Comparison Of Anhydrous Ethanol Production From Ethylene And From Corn Utilizing Life Cycle Analysis Methodology, Gregory Morse

Theses

There is currently much concern with the impact on the environment due to industrial processes. One method to assess this impact is to perform a Life Cycle Analysis (LCA) on the process. Life Cycle Analysis is made up of three stages; Life Cycle Inventory Analysis, Life Cycle Impact Assessment, and Life Cycle Improvement Assessment. In this study, Life Cycle Inventory Analysis methodology was applied to two industrial processes for producing anhydrous ethanol. The first process is the fermentation of corn, and the second is the hydration of ethylene using water and a catalyst. Each process was first modeled using the …

Effect Of Fiber-Matrix Coupling On The Mechanical Properties Of A Totally Bioabsorbable Composite, Barbaro Jesus Perez

Theses

The mechanical properties of a new class of bioabsorbable polymer-composite based on the amino acid tyrosine and calcium phosphate fibers were studied. The effect of the fiber aspect ratio on the elastic modulus of a discontinuous fiber composite was analyzed using the SMC composite micromechanics computer model. The mechanical stiffness of this polymer was found to be superior to that of poly-p-dioxanone, caprolactone and poly-o-ester.

The fiber surface was modified with methane plasma spray to improve the fiber-matrix coupling. The treated fiber composites had 16-40% higher tensile modulus than the untreated fiber composites. From the flexural test results it is …

The Effects Of A Pathway-In-The-Sky Display On Performance Of A Two Axis Tracking Task By Instrument Rated Pilots, Leonard W. Hennessy, Iii

Master's Theses - Daytona Beach

This study was founded on the premise that airplane cockpit operations, while generally safe and relatively efficient, can be made even more so by employing instrument displays which are potentially more intuitive than existing displays. A low fidelity flight simulator was used to conduct an experiment comparing the performance of twenty-four instrument rated pilot subjects on a two axis tracking task (an Instrument Landing System Approach) under three instrument display conditions: (1) conventional instruments (INST); (2) a Pathway-in-the-Sky (PITS) display; and (3) a combination of the two (BOTH). The primary hypothesis, that pilot performance using the PITS and BOTH display …

Dynamic Simulation Of General Aviation Cabin Environments And Occupant Restraint Systems, Mark A. Shilladay

Master's Theses - Daytona Beach

After a five year study of General Aviation (GA) accidents, the National Transportation Safety Board (NTSB) has concluded that aircraft cabin environments place the occupant at high risk of suffering severe injuries in an emergency crash situation. Studies of Federal Aviation Administration (FAA) seat tests were used to form the basis of a computer analysis to address dynamic cabin environments. In this effort a simplified system of masses, springs, and dampers are used to simulate the more complex configuration of cabin structure, seat, pilot, and restraints on a personal computer. The primary objective of this study is to accurately simulate …

Assessment Of Infiltration Practices In The Florida Energy Code, Florida Solar Energy Center, James Cummings

FSEC Energy Research Center®

The Florida Department of Community Affairs has contracted with the Florida Solar Energy Center (FSEC) to review the current infiltration practices of the Florida Energy Code to determine, based on analysis of the best currently available infiltration data, whether there is need for three infiltration practices, and to make recommendations of what "point multipliers" should be applied to the infiltration practice(s). An advisory committee of industry, utility, and research representatives was formed to review the findings of the project and express opinions about the form the infiltration practices should take. This committee met twice, reviewed each of the reports produced …

Radiolabeled Protein Composition And Method For Radiation Synovectomy, D. E. Day, Gary J. Ehrhardt, Kurt R. Zinn

Materials Science and Engineering Faculty Research & Creative Works

A radiolabeled protein composition adapted for radiation therapy which comprises a radioisotope and a protein material containing about 6 or more percent amino acids which have a sulfhydryl-containing side chain. A method for carrying out radiation synovectomy of arthritic joints. Rhenium radiolabeled protein micro- spheres are administered which contain cysteine and other amino acids. A method for radiolabeling a protein composition whereby the composition is treated with a reducing agent capable of reducing disulfides to sulfhydryls prior to radiolabeling.

Liquefaction Of The Alluvial Soils Of Bangladesh, M. A. Mollah

International Conferences on Recent Advances in Geotechnical Earthquake Engineering and Soil Dynamics

In this paper, the potential of the often-saturated sandy soils that occur within the uppermost sub-surface stratigraphy across the Bangladesh plains to experience initial liquefaction due to seismically induced pore water pressure is evaluated. Bore hole logs from development projects were collected. Standard Penetration Test (SPT) values from the drill holes were utilized as the primary data and a widely practiced computational method was employed to estimate the liquefaction potential. The analysis of data indicated that the uppermost portion of the sandy soil layer within 20 m of the surface is loose and sensitive to liquefaction under the influence of …

Acuta Enews April 1995, Vol. 24, No. 4

ACUTA Newsletters

In This Issue

Board Report

President's message

DC at a glance

Directory updates

From ACUTA Headquarters

Low Level Alcohol And Its Residual Effect On A Pilot's Threshold For Detecting Angular Motion, Regina G. Bolinger

Master's Theses - Daytona Beach

The purpose of this study was to examine a pilot's sensitivity to a change in angular motion after alcohol ingestion and determine the duration of effect after the time the blood alcohol content (BAC) reached zero. An earlier study determined that a pilot's threshold for detecting angular motion was affected by 30% with low doses of alcohol ingestion. An important question remaining is whether the pilot's sensitivity to angular motion will continue to be significantly affected after the time BAC reaches zero. Twelve instrument-rated pilots flew a partial panel rotating simulator under an in-flight scenario, and thresholds were measured before …

Modeling For Optimal Management Of Agricultural And Domestic Wastewater Loading To Streams, Muhammad Shafqat Ejaz, Richard C. Peralta

Civil and Environmental Engineering Faculty Publications

A simulation/optimization (S/0) model to aid managing multiobjective wastewater loading to streams while maintaining adequate downstream water quality is presented. The conflicting objectives are to maximize the human and dairy cattle populations from which treated wastewater can be discharged to the river system. Nonindustrial municipal (domestic) wastewater undergoes primary and secondary treatment by a sewage treatment plant (STP) before entering as a steady point source. Dairy wastewater is treated by overland flow (OLF) land treatment before entering the stream as a controlled steady diffuse source. Maximum dual-source loading strategies which do not degrade downstream water quality beyond specified limits are …

A Decision Model For Environmental Assessment Of Process Waste Products, Kyle F. Byard

Theses and Dissertations

Environmental managers must compare the potential impacts of waste products when deciding upon courses of action. The estimation and comparison of these impacts is a subjective process, and few methods of comprehensive, quantitative comparison of waste products currently exist. The intent of this study is to develop a decision methodology to evaluate the environmental impacts of waste products and to score them for comparison. The method will follow established system design principles and incorporate significant characteristics of the waste material. Scores derived to represent the environmental impacts of materials will then he analyzed employing statistical and probabilistic methods to assess …

Estimation Of The Pulmonary Capillary Transport Function In Isolated Rabbit Lungs., Said H. Audi, J H. Linehan, Gary S. Krenz, C A. Dawson, S B. Ahlf, David L. Roerig

Biomedical Engineering Faculty Research and Publications

Recently, we presented a method for estimating the pulmonary capillary volume and transport function based on the use of a reference indicator and two or more indicators that rapidly equilibrate (radially) with the tissue (i.e., the concentrations in the vascular and extravascular spaces at a given axial location are in equilibrium) during transit through the capillaries in a bolus-injection indicator dilution method (S. H. Audi, G. S. Krenz, J. H. Linehan, D. A. Rickaby, and C. A. Dawson. J. Appl. Physiol. 77: 332-351, 1994). The objectives of the present study were 1) to determine whether [¹⁴C]diazepam …

Sensitization To Self (Virus) Antigen By In Situ Expression Of Murine Interferon-Gamma., Myung-Shik Lee, Matthias Von Herrath, Hans Reiser, Michael B.A. Oldstone, Nora Sarvetnick

Journal Articles: Regenerative Medicine

Autoimmune disease results from inflammatory destruction of tissues by aberrant self-reactive lymphocytes. We studied the autoimmune potential of T lymphocytes immunologically ignorant of viral antigens acting as self antigens and whether the host defense molecule IFN-gamma could stimulate these cells to cytotoxic competency. For this purpose, we produced double transgenic mice expressing pancreatic IFN-gamma as well as lymphocytic choriomeningitis virus (LCMV) nucleoprotein (NP) or glycoprotein (GP) antigen. 100% of the NP+/IFN-gamma+ mice became diabetic before 2 mo of age, while none of the NP single transgenic littermates and only 10% of IFN-gamma single transgenic littermates did. Strikingly, NP+/IFN-gamma+ mice spontaneously …

Myasthenia Gravis-Like Syndrome Induced By Expression Of Interferon Gamma In The Neuromuscular Junction., Danling Gu, Lise Wogensen, Nigel A. Calcutt, Chunyao Xia, Simin Zhu, John P. Merlie, Howard S. Fox, Jon Lindstrom, Henry C. Powell, Nora Sarvetnick

Journal Articles: Regenerative Medicine

Abnormal humoral responses toward motor end plate constituents in muscle induce myasthenia gravis (MG). To study the etiology of this disease, and whether it could be induced by host defense molecules, we examined the consequences of interferon (IFN) gamma production within the neuromuscular junction of transgenic mice. The transgenic mice exhibited gradually increasing muscular weakness, flaccid paralysis, and functional disruption of the neuromuscular junction that was reversed after administration of an inhibitor of acetylcholinesterase, features which are strikingly similar to human MG. Furthermore, histological examination revealed infiltration of mononuclear cells and autoantibody deposition at motor end plates. Immunoprecipitation analysis indicated …

Robust Approach To Object Recognition Through Fuzzy Clustering And Hough Transform Based Methods, Tianxiong Fu

Dissertations

Object detection from two dimensional intensity images as well as three dimensional range images is considered. The emphasis is on the robust detection of shapes such as cylinders, spheres, cones, and planar surfaces, typically found in mechanical and manufacturing engineering applications. Based on the analyses of different HT methods, a novel method, called the Fast Randomized Hough Transform (FRHT) is proposed. The key idea of FRHT is to divide the original image into multiple regions and apply random sampling method to map data points in the image space into the parameter space or feature space, then obtain the parameters of …

Measurement Of The Reaction To Stress And Meditation Using Brain Wave Coherence And Heart Rate Variability, Christopher B. King

Theses

Measurement of physiological parameters associated with the stress response and the relaxation response caused by various forms of meditation can provide valuable information about the reaction of the body to the mind and to the external environment.

This study used two different techniques to evaluate physiological parameters. The first part examined the meditation response by recording the EEG and calculating the coherence between brain waves originating from different parts of the brain. It was found that high levels of coherence in the alpha portion of the EEG frequency band coincided with a restful state associated with the relaxation response. In …

Simulation Of Activity Rhythms In The Hamster, Paul Qassis

Theses

In this research, an effort was made to better understand light-dark cycles which influence the physiological and psychological rhythms, circadian rhythms and their behavior. The research concentrated on mathematically modeling circadian rhythms (specifically hamsters' circadian activity rhythms) and establishing a physical correlation and creating a meaningful relationship between the mathematical model's parameters and the real biological oscillators which are responsible for these rhythms. The internal nature of the circadian rhythms is unclear. There is insufficient information and empirical data that describe them. Indirect means have to be employed for the description and exploration of such rhythms. Extensive real data analysis …

Statistical And Finite Element Analysis Of The Effects Of Random Input Parameters On The Mechanical Characteristics Of Sheetmetal Forming Processes Using Quadrature Method, Yu Quan

Theses

In this thesis, the computer aided finite element analysis is implemented in the analysis of sheetmetal forming process. To rationalize the experimentation and analysis, the statistical method is introduced to study the variability of sheetmetal deformation process and final shape with respect to the variation of different parameters.

In Chapter 2, the basic characteristics and considerations of deep drawing operation is described with emphasis on the study of geometrical and physical variables of the forming process.

Chapter 3 discussed the three phases which are encountered in the computer aided finite element analysis. As a typical representative of professional finite element …

In Vitro Characterization Of Transforming Growth Factor-Ss1-Loaded Composites Of Biodegradable Polymer And Mesenchymal Cells, S. B. Nicoll, A. E. Denker, R. S. Tuan

Cells and Materials

A porous, biodegradable polymer composite was fabricated from poly(L-lactic acid) (PLLA) using a solvent- casting particulate-leaching technique, and loaded with recombinant human transforming growth factor ß-1 (TGF-ß1). Tissue culture polystyrene (TCPS) and PLLA disks loaded with bovine serum albumin (BSA) served as controls. Polymer specimens were seeded at high cell density with C3H10T1/2 cells, a mouse embryonic cell line capable of differentiating into various connective tissue cell types. The polymer matrices degraded slowly in physiological saline over four weeks, with a sustained yet sporadic release of active TGF-ß1; a more controlled release of TGF-ß1 was observed in serum-containing culture medium …

Biodegradation Of Synthetic Biphasic Calcium Phosphate And Biological Calcified Substratum By Cells Of Hemopoietic Origin, A. Soueidan, O. I. Gan, J. M. Bouler, F. Gouin, G. Daculsi

Cells and Materials

Different types of osteoclastic cells (authentic osteoclasit from human giant cell tumor and bone marrow of newborn rats; newly-formed osteoclasts from adult rat bone marrow), giant multinucleated cells and macrophages were studied for their effect on synthetic and natural mineralized substrata. Biphasic calcium phosphate ceramic consisted of hydroxyapatite and beta tricalcium phosphate was chosen for in vitro experiments, and dentine served as a positive control for cell resorbing activity . Our results show the limited capacity of authentic and newly-formed osteoclasts to resorb synthetic ceramic as compared to that of natural substrata. In vitro cell-mediated biodegradation included also modifications of …

Resorption Of Natural Calcium Carbonate By Avian Osteoclasts In Vitro, G. Guillemin, S. J. Hunter, C. V. Gay

Cells and Materials

Osteoclasts isolated from the endosteum of 2.5 to 3-week chick tibia were cultured on glass coverslips or natural CaC03 (Tridacna) wafers for 2 and 4 days. The cells were exposed to the pH-dependent dye, acridine orange, and fluorescence was measured by a light microscope photometer. Fluorescence intensity values were higher in cells adherent to Tridacna wafers than in those incubated on glass after 2 and 4 days of culture (three and two-fold, respectively). Moreover, osteoclasts on Tridacna wafers were more flattened and were found to produce resorption pits. Acid production by osteoclasts cultured on Tridacna wafers was stimulated …

Cell Adhesion To Crystal Surfaces: A Model For Initial Stages In The Attachment Of Cells To Solid Substrates, D. Hanein, B. Geiger, L. Addadi

Cells and Materials

This study addresses the mechanism of the chirally-restricted, ROD-independent adhesion of A6 epithelial cells to the {011} faces of calcium {R,R)-tartrate tetrahydrate crystals. The extensive and rapid adhesion of the cells to these surfaces, in the presence or absence of serum proteins, is distinctly different from the extracellular matrix-mediated adhesion to conventional tissue culture surfaces or to the {101} faces of the same crystals. The differences are manifested by insensitivity to ATP depletion, to disruption of microfilaments and microtubules and even to formaldehyde fixation of the cells. Furthermore, trypsin pretreatment does not affect cell attachment to the {011} faces, nor …

Reliability Of Human Fresh And Frozen Gingiva Explant Culture In Assessing Dental Materials Cytocompatibility, R. Warocquier-Clerout, G. C. Hachom-Nitcheu, M. F. Sigot-Luizard

Cells and Materials

An explant culture of human gingival epithelium has been set up in order to provide a valuable test for evaluating the cytocompatibility of dental material s. In an attempt to supply a bank of gingiva ex plants, frozen and freshly excised specimens were cultured in parallel. Optical and scanning electron microscopy showed an early release of cuboidal cells forming a dense layer around the explants. Afterwards, cultures evolved differently . Spread cells grew and migrated more rap idly in fresh than in frozen explant cultures but their adhesion to substratum increased earlier in frozen ones. Epithelial phenotype of cells had …

Biomaterials Associated Infections: The Scale Of The Problem, David J. Stickler, Robert J. C. Mclean

Cells and Materials

The biomaterials used in the manufacture of implanted prosthetic devices profoundly impair the host's ability to opsonise and phagocytose invading microbes. As a result, while these devices generally provide effective relief from painful, crippling and life-threatening disorders, they can also induce vulnerability to infection in the recipients. The surfaces of the implants are susceptible to colonisation by microbial biofilms. The cells in the biofilm.s are further protected against opsonophagocytosis and are also resistant to antibacterials. Device associated infections thus tend to be refractile to antibiotic therapy and in many cases the device has to be removed before the infection will …

Biphasic Sodium Fluoride Effects On Bone And Bone Mineral: A Review, P. -T. Cheng, S. M. Bader, M. D. Grynpas

Cells and Materials

This paper reviews the clinical and experimental findings on the effects of sodium fluoride (NaF) on human and animal bone. NaF has been shown to cause a significant increase in axial skeletal bone mass. However, there is concern that the new bone may not provide the desired increase in bone strength. Yet, NaF remains the most commonly used agent capable of stimulating bone formation in most patients (30% non-responders). But whether NaF reduces vertebral fracture rate (VFR) remains controversial. For a given treatment duration, the effect of F on bone quality appears to depend on dose: there is a marked …

Simtm Turing Machine Simulator, Yin Fu Chen

Theses Digitization Project

No abstract provided.