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Influence Of Circadian Rhythm On The Physical And Mental Performance, Maryam Muhammed Amin Jan 2006

Influence Of Circadian Rhythm On The Physical And Mental Performance, Maryam Muhammed Amin

LSU Master's Theses

This thesis studied the temperature circadian rhythm and its relationship with the physical and mental performance of the individuals. The objectives of this study were to determine (1) the effect of temperature circadian rhythm on the mental and physical performance, (2) whether a common oral temperature circadian rhythm pattern exists for all the participants, (3) the times of the day when the participants perform their best and worst in comparison to their highest and lowest temperatures respectively, (4) find out whether the effect of the oral temperature circadian rhythm on the physical and mental performance is different in males and …

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Use Of Polyhydroxyalkanoates For Denitrification In Recirculating Aquaculture Systems, Maria Teresa Gutierrez-Wing Jan 2006

Use Of Polyhydroxyalkanoates For Denitrification In Recirculating Aquaculture Systems, Maria Teresa Gutierrez-Wing

LSU Doctoral Dissertations

Increasing demand of aquacultural products is driving the industry toward more intensive culture practices. Aquacultural operations are constrained by limitations on the availability high quality waters and regulatory pressures on the discharges. Recirculating systems can address these issues by reducing the amount of water required in the operation. Closed systems are especially suited where biosecurity is important. In closed systems, nitrate accumulates, limiting the time the water can be reused. In marine inland systems, water reuse reduces the cost of salt for make up water. To increase the water reuse time, some form of nitrate removal process must be incorporated …

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Evaluation Of An Amperometric Biosensor For The Detection Of Escherichia Coli O157:H7, Danyelle Denise Small Jan 2006

Evaluation Of An Amperometric Biosensor For The Detection Of Escherichia Coli O157:H7, Danyelle Denise Small

LSU Master's Theses

Escherichia coli O157:H7 contamination is a major hazard in the water supply, causing outbreaks of disease. Conventional methods of E. coli O157:H7 detection usually takes 1-2 days and require hands-on preparation. There is a need to develop a rapid, inexpensive means of detecting the organism. The amperometric biosensor technology has achieved success in the area of metabolite detection. In this study, a bench scale amperometric biosensor was investigated to rapidly detect Escherichia coli O157:H7. The amperometric biosensor consisted of a power source, Clark electrode, autoranging picoammeter, and fabricated polyvinyl chloride (PVC) outer insert with nitrocellulose membrane and attached horseradish peroxidase …

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Gis And 3d Analysis Applied To Sea Turtle Mortalities And Navigation Channel Dredging, Bradley A. Shellito, Keith B. Lockwood Jan 2006

Gis And 3d Analysis Applied To Sea Turtle Mortalities And Navigation Channel Dredging, Bradley A. Shellito, Keith B. Lockwood

Virginia Journal of Science

Between 2000 and 2003 there were an increased number of documented sea turtle mortalities related to hopper dredging in the channels of the Chesapeake Bay. A pilot study was undertaken to create a bathymetric surface and three-dimensional model of the Cape Henry Channel using Geographic Information Systems (GIS) as a visualization tool to examine sea turtle mortalities in relation to the dredging. In Fall 2003, the US Army Corps of Engineers dredged the Thimble Shoals Federal Navigation Channel, and a more refined model was developed using this data. This project examines the growing concerns over sea turtle mortality rates and …

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Recombinant Human Bmp-7 Effectively Prevents Non-Union In Both Young And Old Rats, David J. Hak, Takeshi Makino, Takahiro Niikura, Scott J. Hazelwood, Shane Curtiss, A. Hari Reddi Jan 2006

Recombinant Human Bmp-7 Effectively Prevents Non-Union In Both Young And Old Rats, David J. Hak, Takeshi Makino, Takahiro Niikura, Scott J. Hazelwood, Shane Curtiss, A. Hari Reddi

Biomedical Engineering

The purpose of this study was to evaluate the influence of age on the effectiveness of rhBMP-7 treatment in a fracture with severe periosteal damage that is known to result in non-union formation. Closed stabilized femur fractures were produced in 3-month-old and 18-month-old rats. The fracture site was exposed and 2 mm of the periosteum cauterized circumferentially to impair normal fracture healing. The cauterized fracture site was immediately treated with either 100 mg rhBMP-7 (BMP-7 group), or with 25 xL of vehicle alone (control group). Fracture healing was evaluated with radiographs taken at 3 and 6 weeks. Animals were sacrificed …

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Postharvest Treatment To Control Codling Moth In Fresh Apples Using Water Assisted Radio Frequency Heating, Shaojin Wang, Sohan Birla, J. D. Hansen Jan 2006

Postharvest Treatment To Control Codling Moth In Fresh Apples Using Water Assisted Radio Frequency Heating, Shaojin Wang, Sohan Birla, J. D. Hansen

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Apples destined for export to Japan and South Korea are currently disinfested for codling moth, Cydia pomonella L. (Lepidoptera: Tortricidae), using methyl bromide fumigation. Restrictions and limitations imposed on the uses of methyl bromide have increased interest in developing alternative non-chemical quarantine treatments. It is imperative that the treatment is effective against codling moth yet maintains the quality of treated apples. The present study explored the application of radio frequency (RF) energy in conjunction with conventional hot water treatment to develop feasible heat treatments. Treatment parameters were selected based on minimum time–temperature conditions required for 100% mortality of fifth-instar codling …

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Expert System To Support Site Investigation For Safety Improvement, Andrzej Marcin. Kwasniak, Bogdan Chivoiu, Andrzej P. Tarko Jan 2006

Expert System To Support Site Investigation For Safety Improvement, Andrzej Marcin. Kwasniak, Bogdan Chivoiu, Andrzej P. Tarko

JTRP Technical Reports

One of the goals of traffic safety specialists is to improve road geometry and traffic control at high-crash locations to reduce the risk of crash. The most difficult part of site investigation is determining the causes of crashes. This task may be overwhelming, particularly for inexperienced investigators. Experienced investigators often may have difficulties in connecting various pieces of information and knowledge due to the high level of uncertainty, the high complexity of safety impacts, and the gaps in what is known about driver performance during the crash occurrence. An AI method is proposed to help investigators identify the crash causes. …

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Reduction Of Automobile And Aircraft Collisions With Wildlife In Indiana, David J. Glista, J. Andrew Dewoody, Travis Lee Devault Jan 2006

Reduction Of Automobile And Aircraft Collisions With Wildlife In Indiana, David J. Glista, J. Andrew Dewoody, Travis Lee Devault

JTRP Technical Reports

Conflicts between wildlife and human interests have increased in recent decades due to growing human populations and the resulting expansion of anthropogenic pressures into wildlife habitat. Our overall objectives were to evaluate the the potential impacts of wildlife on transportation in Indiana and vice-versa. The results presented in this final report summarize two aspects of our research: the impact of automotive traffic on wildlife (“road kill”; Part I), and the wildlife hazards present at general aviation airports around the state (“airstrike”; Part II). The road kill dataset indicated that at 13 survey routes traversing 180 linear km of road, 11,068 …

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Design Of Near-Optimal Waveforms For Chest And Abdominal Compression And Decompression In Cpr Using Computer-Simulated Evolution, Charles F. Babbs Jan 2006

Design Of Near-Optimal Waveforms For Chest And Abdominal Compression And Decompression In Cpr Using Computer-Simulated Evolution, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Objective: To discover design principles underlying the optimal waveforms for external chest and abdominal compression and decompression during cardiac arrest and CPR. Method: A 14-compartment mathematical model of the human cardiopulmonary system is used to test successive generations of randomly mutated external compression waveforms during cardiac arrest and resuscitation. Mutated waveforms that produced superior mean perfusion pressure became parents for the next generation. Selection was based upon either systemic perfusion pressure (SPP=thoracic aortic minus right atrial pressure) or upon coronary perfusion pressure (CPP=thoracic aortic pressure minus myocardial wall pressure). After simulations of 64,414 individual CPR episodes, 40 highly evolved waveforms …

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A New Biomechanical Head Injury Criterion, Charles F. Babbs Jan 2006

A New Biomechanical Head Injury Criterion, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

This paper presents a new analysis of the physics of closed head injury caused by intense acceleration of the head. At rest a 1 cm gap filled with cerebrospinal fluid (CSF) separates the human brain from the skull. During impact whole head acceleration induces artificial gravity within the skull. Because its density differs slightly from that of CSF, the brain accelerates, strikes the inner aspect of the rigid skull, and undergoes viscoelastic deformation. Analytical methods for a lumped parameter model of the brain predict internal brain motions that correlate well with published high-speed photographic studies. The same methods predict a …

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A Constitutive Model Of The Human Vocal Fold Cover For Fundamental Frequency Regulation, Kai Zhang, Thomas Siegmund, Roger W. Chan Jan 2006

A Constitutive Model Of The Human Vocal Fold Cover For Fundamental Frequency Regulation, Kai Zhang, Thomas Siegmund, Roger W. Chan

School of Mechanical Engineering Faculty Publications

No abstract provided.

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Cognitively-Engineered Multisensor Data Fusion Systems For Military Applications, Amanda Christine Muller Jan 2006

Cognitively-Engineered Multisensor Data Fusion Systems For Military Applications, Amanda Christine Muller

Browse all Theses and Dissertations

The fusion of imagery from multiple sensors is a field of research that has been gaining prominence in the scientific community in recent years. The technical aspects of combining multisensory information have been and are currently being studied extensively. However, the cognitive aspects of multisensor data fusion have not received so much attention. Prior research in the field of cognitive engineering has shown that the cognitive aspects of any human-machine system should be taken into consideration in order to achieve systems that are both safe and useful. The goal of this research was to model how humans interpret multisensory data, …

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A Formal Language Approach For Detecting Texture Paths And Patterns In Images, Prithviraj S. Patil Jan 2006

A Formal Language Approach For Detecting Texture Paths And Patterns In Images, Prithviraj S. Patil

Browse all Theses and Dissertations

This Master thesis considers the use of formal languages representation for image processing, especially texture patterns and determining texture paths in them. The texture paths are detected and extracted by using image processing techniques, such as image segmentation to isolate regions of interest, and then the extraction of repeating textures. The detection of the texture blocks is obtained by recursively using 27 X 27, 9 X 9, and 3 X 3 windows. Predefined repeating texture patterns are also searched for in each of the sets. For each set of texture blocks with similar or same characteristics, curve fitting techniques are …

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Freight Flows Of Indiana, William R. Black Jan 2006

Freight Flows Of Indiana, William R. Black

JTRP Technical Reports

Using data primarily from the 1997 Commodity Flow Survey (CFS) this report develops a series of models for estimating the production and attraction of 41 different SCTG commodity groups for 145 geographic units in the United States; 92 of these are the counties of Indiana. This is followed by the calibration of fully-constrained gravity models for the flow of these commodities. Using modal share data from the CFS the generated traffic is divided between the various modes. This project looked primarily at the highway sector and used digital representations of these networks for traffic assignment purposes. A very detailed Indiana …

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The Transcriptome Of Human Oocytes, Arif Murat Kocabas, Javier Crosby, Pablo J. Ross, Hasan H. Otu, Zeki Beyhan, Handan Can, Wai-Leong Tam, Guilherme J. M. Rosa, Robert G. Halgren, Bing Lim, Emilio Fernandez, Jose Bernardo Cibelli Jan 2006

The Transcriptome Of Human Oocytes, Arif Murat Kocabas, Javier Crosby, Pablo J. Ross, Hasan H. Otu, Zeki Beyhan, Handan Can, Wai-Leong Tam, Guilherme J. M. Rosa, Robert G. Halgren, Bing Lim, Emilio Fernandez, Jose Bernardo Cibelli

Department of Electrical and Computer Engineering: Faculty Publications

The identification of genes and deduced pathways from the mature human oocyte can help us better understand oogenesis, folliculogenesis, fertilization, and embryonic development. Human metaphase II oocytes were used within minutes after removal from the ovary, and its transcriptome was compared with a reference sample consisting of a mixture of total RNA from 10 different normal human tissues not including the ovary. RNA amplification was performed by using a unique protocol. Affymetrix Human Genome U133 Plus 2.0 GeneChip arrays were used for hybridizations. Compared with reference samples, there were 5,331 transcripts significantly up-regulated and 7,074 transcripts significantly down-regulated in the …

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Use Of Time Domain Reflectometry For Continuous Monitoring Of Nitrate-Nitrogen In Soil And Water, J. O. Payero, David D. Tarkalson, Suat Irmak Jan 2006

Use Of Time Domain Reflectometry For Continuous Monitoring Of Nitrate-Nitrogen In Soil And Water, J. O. Payero, David D. Tarkalson, Suat Irmak

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Nitrate-Nitrogen (NO3-N) losses to ground and surface water are an environmental and agronomic concern in modern crop production systems in the Central Great Plains. Monitoring techniques for nitrogen use in agricultural production are needed to increase crop yield, optimize nitrogen use, and reduce NO3-N leaching. Time domain reflectometry (TDR) could potentially be calibrated to continuously measure NO3-N in soil and water. The objectives of this study were to: (1) evaluate the effect of different factors affecting the response of the bulk electrical conductivity (ECb) sensed by TDR, (2) compare the sensitivity and differences between …

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Land Application Of Manure For Beneficial Reuse, L. M. Risse, M. L. Cabrera, A. J. Franzluebbers, J. W. Gaskin, John E. Gilley, R. Killorn, D. E. Radcliffe, W. E. Tollner, H. Zhang Jan 2006

Land Application Of Manure For Beneficial Reuse, L. M. Risse, M. L. Cabrera, A. J. Franzluebbers, J. W. Gaskin, John E. Gilley, R. Killorn, D. E. Radcliffe, W. E. Tollner, H. Zhang

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The concentration of animal production systems has increased efficiency and improved overall economic return for animal producers. This concentration, along with the advent of commercial fertilizers, has led to a change in the way animal producers view manure. Manure, once valued as a resource by farmers, is now treated as a waste. Air and water quality concerns that arise primarily from the under-utilization or inefficient use of manure contribute to these changing views. However, when properly used, manure is a resource and should be regulated as such. In the United States, the USDA/EPA Unified National Strategy for Animal Feeding Operations …

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Purification And Scale-Up Of A Recombinant Heavy Chain Fragment C Of Botulinum Neurotoxin Serotype E In Pichia Pastoris Gs115, Michael P. Dux, Rick Barent, Jayanta Sinha, Mark Gouthro, Todd Swanson, Ardis Barthuli, Mehmet Inan, John T. Ross, Leonard A. Smith, Theresa J. Smith, Robert Webb, Bonnie Loveless, Ian Henderson, Michael M. Meagher Jan 2006

Purification And Scale-Up Of A Recombinant Heavy Chain Fragment C Of Botulinum Neurotoxin Serotype E In Pichia Pastoris Gs115, Michael P. Dux, Rick Barent, Jayanta Sinha, Mark Gouthro, Todd Swanson, Ardis Barthuli, Mehmet Inan, John T. Ross, Leonard A. Smith, Theresa J. Smith, Robert Webb, Bonnie Loveless, Ian Henderson, Michael M. Meagher

Michael Meagher Publications

A recombinant C-terminus heavy chain fragment from botulinum neurotoxin serotype E (BoNT/E) is proposed as a vaccine against the serotype E neurotoxin. This fragment, rBoNTE(Hc), was produced intracellular in Pichia pastoris GS115 by a three-step fermentation process, i.e., glycerol batch phase and a glycerol fed-batch phase to achieve high cell densities, followed by a methanol fed-batch induction phase. The rBoNTE(Hc) protein was purified from the soluble fraction of cell lysates using three ion-exchange chromatography steps (SP Sepharose Fast Flow, Q Sepharose Fast Flow, Sp Sepharose High Performance) and polished with a hydrophobic charge induction chromatography step …

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Composting Of Biodegradable Municipal Waste In Ireland, Niamh Power, Jerry D. Murphy Jan 2006

Composting Of Biodegradable Municipal Waste In Ireland, Niamh Power, Jerry D. Murphy

Publications

The implementation of the Landfill Directive (96/31/EC) will lead to a massive reduction in quantities of Biodegradable Municipal Waste (BMW), which may be landfilled. In 2016, an estimated 2.6 million tonnes of BMW will require diversion from landfill in Ireland. Recycling of dry paper, reuse of textiles and home composting will divert significant quantities of BMW. However, to divert the quantities required to comply with the Directive a significant proportion of the Organic Fraction of Municipal Solid Waste (OFMSW) will require treatment in centralised biological facilities. A survey was undertaken of composting facilities in Ireland to ascertain present capacity, present …

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Loading And Recovery Behavior Of The Human Lumbar Spine Under Static Flexion, Guntulu Selen Hatipkarasulu Jan 2006

Loading And Recovery Behavior Of The Human Lumbar Spine Under Static Flexion, Guntulu Selen Hatipkarasulu

LSU Doctoral Dissertations

Musculoskeletal disorders account for 32 percent of work related injuries and illnesses. Extensive studies have been conducted to understand and explore the factors that affect the development of musculoskeletal disorders to provide effective control strategies. One of the most important factors that allow effective control strategies is the biomechanical factors. Among the biomechanical risk factors, exposures to repetitive static and vibratory activities are known to result in musculoskeletal disorders. A ligamento–muscular reflex activity exists in humans and animals to stabilize the knee, shoulder, elbow, ankle joints, and spine. This reflex activity decreases over time when static loading is applied, which …

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Change In Conduction Velocity Due To 2d Fiber Curvature In Cultured Neonatal Rat Ventricular Myocytes, Elliot Blake Bourgeois Jan 2006

Change In Conduction Velocity Due To 2d Fiber Curvature In Cultured Neonatal Rat Ventricular Myocytes, Elliot Blake Bourgeois

All ETDs from UAB

Continuum modeling of two-dimensional curved fiber fields has suggested that fiber curvature modulates conduction velocity (CV) in the myocardium. To verify the existence of this effect in living tissue, we measured CV in macroscopically anisotropic monolayers of cultured neonatal rat ventricular myocytes with controlled fiber curvature. A novel growthdirecting substrate was used to produce fiber fields with significant curvature (78°/cm to 333°/cm). Anisotropy ratios (longitudinal CV / transverse CV) measured in cultures grown using this method (n=32) were 2.3±0.3, which is similar to the anisotropy exhibited by human ventricular myocardium. Propagating wavefronts were initiated transverse to fiber orientation in two …

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Speciation Of Alkali Metals In Biomass Combustion And Gasification, Pavankumar Bajrang Sonwane Jan 2006

Speciation Of Alkali Metals In Biomass Combustion And Gasification, Pavankumar Bajrang Sonwane

All ETDs from UAB

Electricity from biomass and biomass–derived fuels has become an attractive and viable alternative energy source. Alkali metals, mainly sodium and potassium, together with other ash forming inorganic components in biomass, increase fouling, slagging, and high temperature corrosion of heat transfer surfaces in boilers thus reduces efficiency during biomass combustion. Future biomass-to-electricity facilities will benefit from increased efficiencies, by incorporating integrated gasification combined cycle systems that use biomass syngas directly in gas turbine. These systems will have even lower tolerances for alkali vapor release, because accelerated erosion and corrosion of turbine blades results in shorter turbine life. One solution to the …

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Predicting Surface Scatter Using A Linear Systems Formulation Of Non-Paraxial Scalar Diffraction, Andrey Krywonos Jan 2006

Predicting Surface Scatter Using A Linear Systems Formulation Of Non-Paraxial Scalar Diffraction, Andrey Krywonos

Electronic Theses and Dissertations

Scattering effects from rough surfaces are non-paraxial diffraction phenomena resulting from random phase variations in the reflected wavefront. The ability to predict these effects is important in a variety of applications including x-ray and EUV imaging, the design of stray light rejection systems, and reflection modeling for rendering realistic scenes and animations of physical objects in computer graphics. Rayleigh-Rice (small perturbation method) and Beckmann-Kirchoff (Kirchhoff approximation) theories are commonly used to predict surface scatter effects. In addition, Harvey and Shack developed a linear systems formulation of surface scatter phenomena in which the scattering behavior is characterized by a surface transfer …

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Observed Web Robot Behavior On Decaying Web Subsites, Joan A. Smith, Frank Mccown, Michael L. Nelson Jan 2006

Observed Web Robot Behavior On Decaying Web Subsites, Joan A. Smith, Frank Mccown, Michael L. Nelson

Computer Science Faculty Publications

We describe the observed crawling patterns of various search engines (including Google, Yahoo and MSN) as they traverse a series of web subsites whose contents decay at predetermined rates. We plot the progress of the crawlers through the subsites, and their behaviors regarding the various file types included in the web subsites. We chose decaying subsites because we were originally interested in tracking the implication of using search engine caches for digital preservation. However, some of the crawling behaviors themselves proved to be interesting and have implications on using a search engine as an interface to a digital library.

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Engineering Education Through Service-Learning In Developing Communities: Two Case Studies, Evan A. Thomas, Andrew Azman Jan 2006

Engineering Education Through Service-Learning In Developing Communities: Two Case Studies, Evan A. Thomas, Andrew Azman

Mechanical and Materials Engineering Faculty Publications and Presentations

This paper provides case studies of two service learning projects that University of Colorado at Boulder (CU-Boulder) students are integrating into their academic experience. The projects focus on developing communities and are managed under the auspices of Engineers Without Borders-USA (EWB-USA), a group founded by Dr. Bernard Amadei, Professor of Civil Engineering at CU-Boulder. These projects expand students? understanding of the social value of their chosen profession, and expose them to a type of engineering significantly different than what is presented in most of their classes. Specifically, focusing on developing communities provides students with the opportunity to design solutions to …

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Stem Cells, Tgf-Ss, And The Adenoviral Mediated Overexpression Of Fibromodulin To Promo Te Incisional Wound Healing, Steven T. Moore Jan 2006

Stem Cells, Tgf-Ss, And The Adenoviral Mediated Overexpression Of Fibromodulin To Promo Te Incisional Wound Healing, Steven T. Moore

All ETDs from UAB

Incision wounds are a clinical problem due to insufficient strength with cosmeti-cally and functionally unacceptable scarring. The primary goals of therapy are increasing the rate of tissue repair and reducing scar stiffness. Assessment of the wounds is neces-sary to determine the state of the tissue in terms of strength, stiffness, and function as well as to compare the efficacy of various treatments and therapies. Mechanical testing can reveal both the speed in which a wound is healing in addition to the amount of scar-ring that is present in a wound. Presently, mesenchymal stem cells have shown potential to heal injured …

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A Simple, Inexpensive, And Effective Light- Carrying Laryngoscopic Blade For Orotracheal Intubation Of Rats, Robert C. Molthen Jan 2006

A Simple, Inexpensive, And Effective Light- Carrying Laryngoscopic Blade For Orotracheal Intubation Of Rats, Robert C. Molthen

Biomedical Engineering Faculty Research and Publications

The research paradigm of using large laboratory animals, in which oroendotracheal intubations are relatively easy, is shifting toward the use of small animals, such as rodents, in which oropharyngeal access is limited, the arytenoid cartilage cycles are faster, and the glottis is much smaller. The considerable growth recently seen in preclinical imaging studies is accompanied by an increased number of rats and mice requiring in vivo intubation for airway management. Tracheal access is important for ventilation, administration of inhaled anesthetics, instillation of drugs or imaging agents, and maintenance of airway patency to reduce mortality during and after operations. I fashioned …

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Polyetheretherketone As A Biomaterial For Spinal Applications, Jeffrey M. Toth, Mei Wang, Bradley T. Estes, Jeffrey L. Scifert, Howard B. Seim, A. Simon Turner Jan 2006

Polyetheretherketone As A Biomaterial For Spinal Applications, Jeffrey M. Toth, Mei Wang, Bradley T. Estes, Jeffrey L. Scifert, Howard B. Seim, A. Simon Turner

Biomedical Engineering Faculty Research and Publications

Threaded lumbar interbody spinal fusion devices (TIBFD) made from titanium have been reported to be 90% effective for single-level lumbar interbody fusion, although radiographic determination of fusion has been intensely debated in the literature. Using blinded radiographic, biomechanic, histologic, and statistical measures, we evaluated a radiolucent polyetheretherketone (PEEK)-threaded interbody fusion device packed with autograft or rhBMP-2 on an absorbable collagen sponge in 13 sheep at 6 months. Radiographic fusion, increased spinal level biomechanical stiffness, and histologic fusion were demonstrated for the PEEK cages filled with autograft or rhBMP-2 on a collagen sponge. No device degradation or wear debris was observed. …

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Evaluation Of Prototype Cell Delivery Catheters Using Agarose Gel And Cell Culture Experiments, Sagar Panse Jan 2006

Evaluation Of Prototype Cell Delivery Catheters Using Agarose Gel And Cell Culture Experiments, Sagar Panse

Theses and Dissertations

Neurodegenerative diseases and brain tumors affect millions of patients worldwide and are associated with significant morbidity and mortality. The blood brain barrier constitutes a major obstacle to delivery of therapeutic agents administered systemically for treating these disorders. Intracranial drug delivery provides a novel way of bypassing the blood brain barrier and achieving high concentration of therapeutic agents in the brain while avoiding systemic side effects. However damage to tissues during insertion of catheters, release of air in the brain and consequent backtracking of dye are some disadvantages with this mode of treatment. We evaluated prototype cell delivery catheters (each with …

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Smooth Key-Framing Using The Image Plane, Leon Barrett, Cindy Grimm Jan 2006

Smooth Key-Framing Using The Image Plane, Leon Barrett, Cindy Grimm

All Computer Science and Engineering Research

This paper demonstrates the use of image-space constraints for key frame interpolation. Interpolating in image-space results in sequences with predictable and controlable image trajectories and projected size for selected objects, particularly in cases where the desired center of rotation is not fixed or when the key frames contain perspective distortion changes. Additionally, we provide the user with direct image-space control over {\em how} the key frames are interpolated by allowing them to directly edit the object's projected size and trajectory. Image-space key frame interpolation requires solving the inverse camera problem over a sequence of point constraints. This is a variation …

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