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Embedded Noninteractive Continuous Bot Detection, Roman V. Yampolskiy, Venu Govindaraju Mar 2008

Embedded Noninteractive Continuous Bot Detection, Roman V. Yampolskiy, Venu Govindaraju

Faculty and Staff Scholarship

Multiplayer online computer games are quickly growing in popularity, with millions of players logging in every day. While most play in accordance with the rules set up by the game designers, some choose to utilize artificially intelligent assistant programs, a.k.a. bots, to gain an unfair advantage over other players. In this article we demonstrate how an embedded noninteractive test can be used to prevent automatic artificially intelligent players from illegally participating in online game-play. Our solution has numerous advantages over traditional tests, such as its nonobtrusive nature, continuous verification, and simple noninteractive and outsourcing-proof design. © 2008 ACM.


Network Visualization Design Using Prefuse Visualization Framework, John Mark Belue Mar 2008

Network Visualization Design Using Prefuse Visualization Framework, John Mark Belue

Theses and Dissertations

Visualization of network simulation events or network visualization is an effective and low cost method to evaluate the health and status of a network and analyze network designs, protocols, and network algorithms. This research designed and developed a network event visualization framework using an open source general visualization toolkit. This research achieved three major milestones during the development of this framework: A robust network simulator trace file parser, multiple network visualization layouts {including user-defined layouts, and precise visualization timing controls and integrated display of network statistics. The parser architecture is extensible to allow customization of simulator trace formats that are …


Particle Swarm Optimization: Basic Concepts, Variants And Applications In Power Systems, Yamille Del Valle, Ganesh K. Venayagamoorthy, Salman Mohagheghi, Ronald G. Harley, J. C. Hernandez Mar 2008

Particle Swarm Optimization: Basic Concepts, Variants And Applications In Power Systems, Yamille Del Valle, Ganesh K. Venayagamoorthy, Salman Mohagheghi, Ronald G. Harley, J. C. Hernandez

Electrical and Computer Engineering Faculty Research & Creative Works

Many areas in power systems require solving one or more nonlinear optimization problems. While analytical methods might suffer from slow convergence and the curse of dimensionality, heuristics-based swarm intelligence can be an efficient alternative. Particle swarm optimization (PSO), part of the swarm intelligence family, is known to effectively solve large-scale nonlinear optimization problems. This paper presents a detailed overview of the basic concepts of PSO and its variants. Also, it provides a comprehensive survey on the power system applications that have benefited from the powerful nature of PSO as an optimization technique. For each application, technical details that are required …


Computational Models Of Tandem Src Homology 2 Domain Interactions And Application To Phosphoinositide 3-Kinase, Dipak Barua, James R. Faeder, Jason M. Haugh Mar 2008

Computational Models Of Tandem Src Homology 2 Domain Interactions And Application To Phosphoinositide 3-Kinase, Dipak Barua, James R. Faeder, Jason M. Haugh

Chemical and Biochemical Engineering Faculty Research & Creative Works

Intracellular signal transduction proteins typically utilize multiple interaction domains for proper targeting, and thus a broad diversity of distinct signaling complexes may be assembled. Considering the coordination of only two such domains, as in tandem Src homology 2 (SH2) domain constructs, gives rise to a kinetic scheme that is not adequately described by simple models used routinely to interpret in vitro binding measurements. To analyze the interactions between tandem SH2 domains and bisphosphorylated peptides, we formulated detailed kinetic models and applied them to the phosphoinositide 3-kinase p85 regulatory subunit/platelet-derived growth factor β-receptor system. Data for this system from different in …


Macro-Mixing In A Draft-Tube Airlift Bioreactor, Hu Ping Luo, Muthanna H. Al-Dahhan Mar 2008

Macro-Mixing In A Draft-Tube Airlift Bioreactor, Hu Ping Luo, Muthanna H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

Airlift Reactors Are Pneumatically Agitated Reactors that Have Been Widely Used in Industries, Particularly in Bioprocesses. Extensive Studies About the Flow Dynamics in Airlift Column Reactors Exist; However, Most of These Studies Have Focused on Global Hydrodynamic Parameters using Conventional Techniques. the Local Flow Characteristics, such as the Macro-Mixing and the Turbulence Intensity, Are Crucial for Reliable Design and Scale-Up, and They Remain Unclear. This Work Focuses on Studying the Macro-Mixing in a Draft-Tube Airlift Bioreactor Utilizing an Advanced Flow Dynamic Measurement Technique, Computer Automated Radioactive Particle Tracking (CARPT). True Residence Time Distribution Analyses for the overall Column as Well …


Mission Impact Analysis Visualization For Enhanced Situational Awareness, Sean C. M. Carroll Mar 2008

Mission Impact Analysis Visualization For Enhanced Situational Awareness, Sean C. M. Carroll

Theses and Dissertations

This research effort examines the creation of mission impact analysis visualizations to enhance situational awareness. It focuses on using prefuse to create a visualization that allows the user to quickly understand the impact of the failure of any element needed directly or indirectly for a mission. The visualization correctly identifies the direct or indirect impact on physical requirements such as network links and servers as well as non-physical elements such as the generation of a report, or ability to perform a task. The visualization provides an overview of the situation, as well as including enhancements to allow for greater detail …


Evaluating Security And Quality Of Service Considerations In Critical Infrastructure Communication Networks, Gregory R. Roberts Mar 2008

Evaluating Security And Quality Of Service Considerations In Critical Infrastructure Communication Networks, Gregory R. Roberts

Theses and Dissertations

This thesis demonstrates the benefits of utility communication based on Internet technology, some dangers in using Internet technology in establishing a utility intranet connecting protection and control systems, and compares three different approaches to making reservations for routing traffic in the utility intranet based on different levels of background traffic. A model of expected background traffic on a national utility intranet is presented. The Utility Communication Architecture 2.0 and the International Electrotechnical Commission (IEC) 61850 began laying the groundwork in 2002 in establishing an infrastructure allowing power substations, program logic controllers, remote terminal units, intelligent electronic devices, and other devices …


Design And Optimization Of Broadband High Impedance Ground Planes (Higp) For Surface Mount Antennas, Murat Dogrul Mar 2008

Design And Optimization Of Broadband High Impedance Ground Planes (Higp) For Surface Mount Antennas, Murat Dogrul

Theses and Dissertations

Gain and bandwidth metrics of broad-band low-profile antennas severely deteriorate when they are placed conformally onto the conductive skins of air, sea, and ground platforms. This detrimental effect is primarily due to out-of-phase reflections from the conductive body interfering with the antenna’s self radiation. Furthermore, lateral waves launched by the antenna couple into the thin substrate placed between the antenna and the platform, giving rise to surface waves resulting in significant diffraction from the edges of the substrate. To remedy these two major mechanisms degrading antenna performance, high impedance ground planes (HIGP) were designed. HIGPs made of a 2-dimensional periodic …


A Simulation Optimization Approach To The Design Of Unmanned Aircraft Systems, Emily C. Evans Mar 2008

A Simulation Optimization Approach To The Design Of Unmanned Aircraft Systems, Emily C. Evans

Theses and Dissertations

Military strategy and operations have evolved significantly over the past decade. This evolution has led to a change in the military resources required to carry out missions successfully. In line with these requirements, demand has increased for unmanned aerial vehicles (UAV) with enhanced capability to perform surveillance and to strike targets of interest. This research effort aids in the design of a next generation UAV by employing a simulation optimization approach. The goal of this research is to maximize the number of targets destroyed in a conflict scenario by a newly designed UAV that is subject to size, weight, and …


Semantic Components: A Model For Enhancing Retrieval Of Domain- Specific Information, Susan Loucette Price Mar 2008

Semantic Components: A Model For Enhancing Retrieval Of Domain- Specific Information, Susan Loucette Price

Dissertations and Theses

Despite the success of general Internet search engines, information retrieval remains an incompletely solved problem. Our research focuses on supporting domain experts when they search domain-specific libraries to satisfy targeted information needs. The semantic components model introduces a schema specific to a particular document collection. A semantic component schema consists of a two-level hierarchy, document classes and semantic components. A document class represents a document grouping, such as topic type or document purpose. A semantic component is a characteristic type of information that occurs in a particular document class and represents an important aspect of the document’s main topic. …


Acuta Enews February 2008, Vol. 37, No. 2 Feb 2008

Acuta Enews February 2008, Vol. 37, No. 2

ACUTA Newsletters

ln This lssue

From the President........ Walt Magnussen, Texas A&M Univ., ACUTA President

Board Report ................... Riny Ledgerwood, San Diego Stale Univ, , ACUTA, Sec./Treasurer

Check lt Out: RFls/RFPs, Job Postings, Press Releases

Tech Talk: What Kind of Experience Does Your Website Provide?.............Kevin Tanzillo, Dux PR

DC Update ............Jeanne Jansenius, Sewonee, The University of the South

Grant Money for Minority College Wireless Networks

Ethernet Alliance White Paper Challenge

lnfo Links ............. Randy Hayes, Univ. of Northern lowa

Deadline for lnstitutional Excellence Awards ls February 15

Welcome New Members


Integrating Random Testing With Constraints For Improved Efficiency And Diversity, Yoonsik Cheon, Antonio Cortes, Martine Ceberio, Gary T. Leavens Feb 2008

Integrating Random Testing With Constraints For Improved Efficiency And Diversity, Yoonsik Cheon, Antonio Cortes, Martine Ceberio, Gary T. Leavens

Departmental Technical Reports (CS)

Random testing can be fully automated, eliminates subjectiveness in constructing test cases, and increases the diversity of test data. However, randomly generated tests may not satisfy program's assumptions (e.g., method preconditions). While constraint solving can satisfy such assumptions, it does not necessarily generate diverse tests and is hard to apply to large programs. We blend these techniques by extending random testing with constraint solving, improving the efficiency of generating valid test data while preserving diversity. For domains such as objects, we generate input values randomly; however, for values of finite domains such as integers, we represent test data generation as …


Effects Of Climate Change On Aquatic Invasive Species And Implications For Management And Research, Roxanne Thomas, Austin Kane, Environmental Law Institute, Britta G. Bierwagen Feb 2008

Effects Of Climate Change On Aquatic Invasive Species And Implications For Management And Research, Roxanne Thomas, Austin Kane, Environmental Law Institute, Britta G. Bierwagen

United States Environmental Protection Agency: Publications

Global change stressors, including climate change and variability and changes in land use, are major drivers of ecosystem alterations. Invasive species, which are non-native species that cause environmental or economic damages or human-health impacts, also contribute to ecosystem changes. The interactions between stressors and invasive species, although not well understood, may exacerbate the impacts of climate change on ecosystems, and likewise, climate change may enable further invasions. This report reviews available literature on climate-change effects on aquatic invasive species (AIS) and examines state-level AIS management activities. Data on management activities came from publicly available information, was analyzed with respect to …


The State Of The Art In Flow Visualization: Partition-Based Techniques, Tobias Salzbrunn, Heike Janicke, Thomas Wischgoll, Gerik Scheuermann Feb 2008

The State Of The Art In Flow Visualization: Partition-Based Techniques, Tobias Salzbrunn, Heike Janicke, Thomas Wischgoll, Gerik Scheuermann

Computer Science and Engineering Faculty Publications

Flow visualization has been a very active subfield of scientific visualization in recent years. From the resulting large variety of methods this paper discusses partition-based techniques. The aim of these approaches is to partition the flow in areas of common structure. Based on this partitioning, subsequent visualization techniques can be applied. A classification is suggested and advantages/disadvantages of the different techniques are discussed as well.


Bifidobacteria In Feces And Environmental Waters, Regina Lamendella, Jorge W. Santo Domingo, Catherine Kelty, Daniel B. Oerther Feb 2008

Bifidobacteria In Feces And Environmental Waters, Regina Lamendella, Jorge W. Santo Domingo, Catherine Kelty, Daniel B. Oerther

United States Environmental Protection Agency: Publications

Bifidobacteria have been recommended as potential indicators of human fecal pollution in surface waters even though very little is known about their presence in nonhuman fecal sources. The objective of this research was to shed light on the occurrence and molecular diversity of this fecal indicator group in different animals and environmental waters. Genus- and species-specific 16S rRNA gene PCR assays were used to study the presence of bifidobacteria among 269 fecal DNA extracts from 32 different animals. Twelve samples from three wastewater treatment plants and 34 water samples from two fecally impacted watersheds were also tested. The species-specific assays …


Mineral Trioxide Aggregate Material Use In Endodontic Treatment: A Review Of The Literature, Howard W. Roberts, Jeffrey M. Toth, David W. Berzins, David G. Charlton Feb 2008

Mineral Trioxide Aggregate Material Use In Endodontic Treatment: A Review Of The Literature, Howard W. Roberts, Jeffrey M. Toth, David W. Berzins, David G. Charlton

Biomedical Engineering Faculty Research and Publications

Objective

The purpose of this paper was to review the composition, properties, biocompatibility, and the clinical results involving the use of mineral trioxide aggregate (MTA) materials in endodontic treatment.

Methods

Electronic search of scientific papers from January 1990 to August 2006 was accomplished using PubMed and Scopus search engines (search terms: MTA, GMTA, WMTA, mineral AND trioxide AND aggregate).

Results

Selected exclusion criteria resulted in 156 citations from the scientific, peer-reviewed dental literature. MTA materials are derived from a Portland cement parent compound and have been demonstrated to be biocompatible endodontic repair materials, with its biocompatible nature strongly suggested by …


Leg Sympathetic Response To Noxious Skin Stimuli Is Similar In High And Low Level Human Spinal Cord Injury, M. Kevin Garrison, Alexander V. Ng, Brian D. Schmit Feb 2008

Leg Sympathetic Response To Noxious Skin Stimuli Is Similar In High And Low Level Human Spinal Cord Injury, M. Kevin Garrison, Alexander V. Ng, Brian D. Schmit

Biomedical Engineering Faculty Research and Publications

Objective

To determine if sympathetically mediated vasoconstriction in the lower extremities is injury level dependent. Although sympathetic responses have been measured in the limbs of people with high and low level SCI using blood flow measurements, including Doppler ultrasound and venous plethysmography, a direct comparison between injury levels has not been made.

Methods

Volunteers with chronic SCI were grouped according to injury level. Above T6: high level (HL, n = 7), and T6 and below: low level (LL, n = 6). All subjects had complete motor and sensory loss. Leg arterial flows were recorded by venous occlusion plethysmography, and continuous …


Bifidobacteria In Feces And Environmental Waters, Regina Lamendella, Jorge W. Santo Domingo, Catherine A. Kelty, Daniel B. Oerther Feb 2008

Bifidobacteria In Feces And Environmental Waters, Regina Lamendella, Jorge W. Santo Domingo, Catherine A. Kelty, Daniel B. Oerther

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Bifidobacteria have been recommended as potential indicators of human fecal pollution in surface waters even though very little is known about their presence in nonhuman fecal sources. The objective of this research was to shed light on the occurrence and molecular diversity of this fecal indicator group in different animals and environmental waters. Genus- and species-specific 16S rRNA gene PCR assays were used to study the presence of bifidobacteria among 269 fecal DNA extracts from 32 different animals. Twelve samples from three wastewater treatment plants and 34 water samples from two fecally impacted watersheds were also tested. The species-specific assays …


Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle Feb 2008

Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle

Conference Papers

Coronary stent implantation can improve blood flow in an artery that has been narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). The degree of tissue prolapse between stent struts may be an important factor in predicting the restenosis rate of a stent due to the haemodynamic influence of the protruding tissue. In this paper a mathematical model has been developed to numerically predict the tissue prolapse for an artery implanted with a coronary stent. The prolapse model has been applied to the Gianturco-Roubin II (GR-II) …


Digestion Of Sand-Laden Manure Slurry In An Upflow Anaerobic Solids Removal (Uasr) Digester, Khursheed Karim, Rebecca Hoffmann, M. (Muthanna) H. Al-Dahhan Feb 2008

Digestion Of Sand-Laden Manure Slurry In An Upflow Anaerobic Solids Removal (Uasr) Digester, Khursheed Karim, Rebecca Hoffmann, M. (Muthanna) H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

Studies on the Performance of a Laboratory Scale Up flow Anaerobic Solids Removal (UASR) Digester Were Carried Out using Sand-Laden Cow Manure Slurries Having Total Solids (TS) Concentration as 50 and 100 G/l. Hydraulic Retention Time (HRT) Was Maintained as 32.4 Days, Which Resulted in the Volatile Solids (VS) Loading Rates of 1 and 1.64 G/l D. the UASR System Was Designed to Remove Sand from the Manure Slurry, While Anaerobically Digesting Biodegradable Solids Inside a Single Reactor. to Enhance the Contact of Microorganisms and Substrate, the Liquor from the Top of the Digester Was Recirculated through the Bed of …


Development Of Calcium Sulfate – Ggbs – Portland Cement Binders, Brian O'Rourke, Ciaran Mcnally, Mark G. Richardson Jan 2008

Development Of Calcium Sulfate – Ggbs – Portland Cement Binders, Brian O'Rourke, Ciaran Mcnally, Mark G. Richardson

Publications

Binders manufactured using a blend of gypsum, ground granulated blast furnace slag and Portland cements are technically viable and possess considerable environmental and economic advantages when compared to binders manufactured using Portland cement alone. As such, the evaluation of binders made from these materials offers a promising research focus in the quest to produce technically sound, environmental and economical binders for specialist uses as an alternative to traditional concrete binders of higher carbon footprint. The aim of the test programme was to investigate the viability of a series of binders designed to fulfil particular user needs while having significantly decreased …


Pattern Recognition Of Brain Fmri Images For Various Physiological States, Priyanka Bhatt Jan 2008

Pattern Recognition Of Brain Fmri Images For Various Physiological States, Priyanka Bhatt

Theses

The development of fMRI (functional Magnetic Resonance Imaging) has led many researchers to localize brain functions using different stimuli. The use of pattern recognition techniques have made it possible to predict the stimuli being presented from the corresponding brain images and activation patterns. The primary objective of the present study was to use pattern recognition methods to develop a model using available fMRJ images and then to use the model to identify the stimulus presented from a large number of unknown images. Two different experimental conditions were used involving both binary and multi-class classification. Bilateral finger tapping data which had …


Brain Segmentation Using Endogenous Contrast Mechanism Using Breath Holding Fmri Signal For Tissue Characterization, Samata Mukesh Kakkad Jan 2008

Brain Segmentation Using Endogenous Contrast Mechanism Using Breath Holding Fmri Signal For Tissue Characterization, Samata Mukesh Kakkad

Theses

MRL has fast become the modality of choice for the analysis of the complexity of the human brain. MRJ is a non-invasive method and gives high spatial resolution maps of the brain with soft tissue contrast. Conventional MRI technique modified to be used to image the functionality at high temporal resolution is known as fMRI. In fMRI the BOLD signal we measure is the hemodynamic response to neuronal and vascular changes at rest or in response to a stimulus where the various tissue types will have a different response.

While fMRI has been traditionally been used to detect and identify …


Mapping Inter-Subject And Inter-Regional Brain Connectivity During Free Viewing Of Novel Natural Scenes, Sheela Nagaraj Jan 2008

Mapping Inter-Subject And Inter-Regional Brain Connectivity During Free Viewing Of Novel Natural Scenes, Sheela Nagaraj

Theses

Traditional functional magnetic resonance imaging (fMRI) studies have used controlled tasks such as finger tapping to isolate function in distinct cortical. Recent studies have examined the mechanisms involved during natural conditions by asking subjects to freely view the presentation of a movie. The objective of our study was to further observe the extent to which similarities are present between subjects during natural vision. It was hypothesized that there would be a linear relationship between the percentage of region-specific overlap, which is the percent of the anatomical region of interest which contains spatial activation exhibited by all six subjects, and corresponding …


Ultra-Fine Particle Formation Using Principle Of Rapid Expansion Of Supercritical Solutions`, Miraj Minesh Sheth Jan 2008

Ultra-Fine Particle Formation Using Principle Of Rapid Expansion Of Supercritical Solutions`, Miraj Minesh Sheth

Theses

There are indications in the chemical and pharmaceutical industries that the reduction in size of a crystalline particle can lead to better performance of the drug compound, particularly for water insoluble drugs, in the final dosage form. Many particle formation techniques have been investigated in recent years by researchers to obtain desired particulate sizes and size distributions. Supercritical fluid technologies have been successfully investigated for particle formation due to its unique gas/liquid properties in the supereritical state. In this report, results of particle formation using the principles of Rapid Expansion of Supercritical Solutions (RESS) have been documented.

In the RESS …


The Extraction Of Type 1 Collagen And The Fabrication Of Multi-Filament Embedded Hydrogels For Guided Nerve Regeneration, Mevan Lakmal Siriwardane Jan 2008

The Extraction Of Type 1 Collagen And The Fabrication Of Multi-Filament Embedded Hydrogels For Guided Nerve Regeneration, Mevan Lakmal Siriwardane

Theses

Each year, there are approximately 11,000 new cases of spinal cord injury (SCI) in the United States [2]. There have been some success in pre-clinical studies to induce axonal generation, but the reconnection of axons over large distances remains the greatest challenge. Since the development of nerve conduit to facilitate general axonal regeneration, the primary focus has changed to directing the regeneration of axons while also promoting their outgrowth over very extensive lesions to ensure functional recovery of transected nerves during in vitro experiments by using natural materials such as type I collagen, which is the largest constituent of the …


Fracture Healing : The Effects Of Local Insulin Delivery Via Calcium Sulfate And Tricalcium Phosphate, Sarah Elizabeth Buchala Jan 2008

Fracture Healing : The Effects Of Local Insulin Delivery Via Calcium Sulfate And Tricalcium Phosphate, Sarah Elizabeth Buchala

Theses

Previous studies have documented the major role played by insulin in osseous healing. This is the first study to examine local intramedullary insulin delivery to the fracture site and its effect upon the normal fracture healing process. Preceding results show that when administered at the fracture site of the impaired fracture healing model of the diabetic BB Wistar rat, insulin will regulate early cellular proliferation and chondrogenesis and late mineralized tissue, cartilage content and mechanical strength.

In this study, two novel delivery vehicles have been evaluated for sustained insulin release in the normal fracture model of the BB Wistar rat. …


Comparison Of Linear Parametric Models For Predicting Fmri Response, Parina Gandhi Jan 2008

Comparison Of Linear Parametric Models For Predicting Fmri Response, Parina Gandhi

Theses

In this study, five different linear parametric models including Autoregressive model (ARX), Autoregressive Moving Average Model (ARMAX), Box-Jenkins Model (BJ), Instrument Variable Model (IV) and Prediction Error Model (PEM) were used to predict the fMRI response and their performances compared. Transfer functions were computed for every voxel time series for every subject using all the parametric models. Cross-correlation was subsequently performed between the predicted response and the actual fMRI data to compare the performance of the five models. The consistency of the models and the transfer function was checked by doing a statistical analysis. Among the five models tested, PEM …


Dexamethasone- And Age-Sensitive Genes In Neonatal Small Intestine, Carla Cerqueira Jan 2008

Dexamethasone- And Age-Sensitive Genes In Neonatal Small Intestine, Carla Cerqueira

Theses

Regulation of GLUT5 is dependent on the presence of its substrate, fructose, but it is also correlated with the developmental (aging) process of the intestine. To identify fructose-responsive genes whose expression also changes with age, intestines of 10 and 20 d old pups were perfused, by Ferraris et al., with fructose and then compared by microarray analysis. From this, a gene clustering analysis revealed that some age- and fructose-specific genes are regulated by corticosterones, which normally increase in pups ≥ 14 d old. Subsequent work indicated that priming the gut with Dexamethasone (Dex, a glucocorticoid analog) allowed fructose to precociously …


Penetration Force Measurements In The Central Nervous System With Silicon Electrodes, Ashwini Arun Nikam Jan 2008

Penetration Force Measurements In The Central Nervous System With Silicon Electrodes, Ashwini Arun Nikam

Theses

One of the major challenges in neural engineering is the tissue damage that occurs during insertion of microelectrodes into the central nervous system. The damage occurs as a result of the dimpling effect that is due to the insertion force. A method which can reduce the penetration force can also reduce dimpling and the resulting tissue damage.

There are two objectives in this thesis. One is to measure the penetration force with Michigan electrodes, which are silicon based electrodes. The second is to reduce the penetration force by using mechanical vibrations.

First, the penetration force was measured in the rat …