Digital Commons Network^™

Synthesis And Assessment Of Biobased Acrylated Epoxidized Soybean Oil Resins For Stereolithography 3d Printing Of Microfluidic Devices, Natalie S. Romero Figueroa

College of Graduate Studies: Theses & Dissertations

This research focuses on the development and characterization of a biobased photocurable resin synthesized from soybean oil for use in stereolithography (SLA) 3D printing of microfluidic devices. The study explores a sustainable alternative to petroleum-based resins by performing an acrylation reaction on epoxidized soybean oil (ESO) to produce acrylated epoxidized soybean oil (AESO), which was then formulated into a photocurable resin with the addition of a photo initiator. The fabrication process involved designing microfluidic molds in SolidWorks and printing them using an Elegoo Mars 4 SLA printer under various exposure and layer thickness parameters. The printed samples consisted of microchannels …

Achieving Urban Resilience Strategies For Cities, Rehab Abdelfatah Abdel Aziz. Mahmoud

Mansoura Engineering Journal

The concept of the Resilient City is a relatively recent addition to urban planning discussions, gaining global attention due to the increasing need for cities to withstand urban, social, and environmental challenges. Urban resilience, alongside adaptability, plays a vital role in addressing these dynamic transformations. This research investigates how to implement urban resilience strategies to effectively respond to ongoing changes and sudden crises, such as terrorist attacks and natural disasters like floods, earthquakes, and hurricanes. The research identifies a critical gap in the absence of a comprehensive theoretical framework for evaluating the success of urban resilience strategies within cities’ planning …

Development Of A Compliant Soft Gripper With Embedded Force Sensors, Ayman Abbas, Abdelrahman Said, Tamer Kahlil, Mahmoud Magdy

Mechanical Engineering

Robotic manipulators have the capability to perform repetitive tasks with a level of efficiency and precision that exceeds the capabilities of human operators. Currently, they are commonly found and extensively utilized across various disciplines. However, robotic manipulators have gradually begun to make inroads into fields beyond manufacturing, such as medicine and agriculture. Due to the diverse range of industries utilizing robotic manipulators, the nature of tasks assigned to these devices can often be more intricate and multifaceted than conventional assignments. Hence, conventional mechanical grippers may not always be suitable, prompting a growing need for grippers capable of adapting to effectively …

Merging Biophilic Design Approach Into University Learning Interior Spaces: An Applied Experience, Sara M. Atwa

Mansoura Engineering Journal

Incorporating living elements into educational environments is a crucial matter, as many educational spaces are deprived of natural features. Designers should incubate this way of thinking to generate healthy and inspiring spaces for students. The biophilia hypothesis reveals that humankind has a genuine connection with the natural environment which makes us happier and healthier. Biophilic design has motivated architects to merge nature within the interior spaces using plants, reclaimed wood, water features, and daylight. Thereby, this manuscript debates that educational spaces – particularly in universities – requisite a sincere interaction with the nature environment by embracing biophilic design as an …

Lung Uptake Of Two Spect Markers Identifies Sensitivity To Hyperoxia-Induced Acute Respiratory Distress Syndrome In Rats, Anne V. Clough, Taheri Pardis, Guru P. Sharma, Ming Zhao, Elizabeth R. Jacobs, Said H. Audi

Biomedical Engineering Faculty Research and Publications

Introduction: Exposure of adult rats to hyperoxia is a well-established model of human Acute Respiratory Distress Syndrome (ARDS). Although rats exposed to 100% O₂ display clinical evidence of lung injury after ∼40 h and death by 72 h, rats exposed to 60% O₂ for up to 7 days show little sign of injury. However, when subsequently exposed to hyperoxia, these pre-exposed rats become more susceptible to ARDS. The objective of this study is to evaluate the ability of imaging biomarkers to track this hyperoxia susceptibility and to elucidate underlying mechanisms.

Methods: Sprague-Dawley rats were exposed to either room …

Agency, Index & Process: Investigating The Role Of The Artist’S Body In Digital Sculpture Production, Alan Magee

Doctoral

Contemporary Digital Sculpture has emerged out of recent developments in digital art, 3d modelling and virtual modes of production. These advances range from the creation of more powerful software and hardware systems to the to nascent XR sectors, and the potential for materialisation through technologies such as 3d printing, laser-cutting, or CNC1 machining. However, critical discourse remains predominantly focused on the end product, often overlooking the embodied labour processes inherent in its creation. As revealed through indexical traces of the artist’s body, these processes encapsulate the gestures, actions and subjective agency of artistic activity. Consequently, with the limitations of digital …

Enhancing Image Classification Using A Convolutional Neural Network Model, Zena M. Saadi, Ahmed T. Sadiq, Omar Z. Akif, Marwa M. Eid

Journal of Soft Computing and Computer Applications

In recent years, with the rapid development of the current classification system in digital content identification, automatic classification of images has become the most challenging task in the field of computer vision. As can be seen, vision is quite challenging for a system to automatically understand and analyze images, as compared to the vision of humans. Some research papers have been done to address the issue in the low-level current classification system, but the output was restricted only to basic image features. However, similarly, the approaches fail to accurately classify images. For the results expected in this field, such as …

A Predictive Framework Combining Iot And Machine Learning Regression Models For Smart Precision Farming, Kusum Yadav, Nesreen Abdou El-Hadiede

NJF Intelligent Engineering Journal

In this paper, the Internet of Things (IoT) and machine learning algorithms that incorporate regressor are integrated to improve precision agriculture. Data from Internet of Things sensors like temperature sensors, humidity sensors, and soil sensors can be collected and analysed using machine learning algorithms like Support Vector Machines (SVMs) and Multilayer Perceptrons (MLPs). By using the proposed system, crop yield will be optimised, resource usage will be minimised, and the environmental impact of agriculture will be reduced. A comparison of predictive accuracy and error metrics, such as RMSE, demonstrated the effectiveness of automated monitoring, predicting crop health issues, and implementing …

Comparative Analysis Of Nature-Inspired Optimization Algorithms: Applications, Challenges And Future Directions, Prerna Mann

NJF Intelligent Engineering Journal

With the proliferation of data generation, the process of achieving optimal solutions is getting more complex. It is becoming increasingly clear that intelligent metaheuristics algorithms are the way to go for solving these complicated optimisation problems, particularly when faced with several restrictions. The development of effective methods for dealing with these optimisation challenges has prompted the creation of numerous new algorithms. These algorithms are either improving their ability to handle problems in many domains or are investigating new contexts in which they could be useful. The field is advancing at a quick pace, leaving many in the dark about its …

Black Soldier Fly Larvae (Bsfl) Bioconversion For Circular Economy: A Study In Polaman Village, Siswo Sumardiono, Rizka Amalia, Syaikha Butsaina Dhiya’Ulhaq, Nurika Nazilatul Ilmi, Hermawan Dwi Ariyanto

ASEAN Journal of Community Engagement

Conventional organic waste management methods often lead to environmental degradation and underutilization of valuable resources. In rural areas, such as Polaman Village, limited awareness and inefficient disposal systems exacerbate these issues, thus necessitating innovative and sustainable solutions. This study explores black soldier fly larvae (BSFL) bioconversion as a community-based solution for organic waste management, addresses environmental challenges, and promotes economic empowerment by converting waste into valuable by-products. The study employed a mixed-methods approach, beginning with baseline assessments of waste generation and existing management practices to identify community needs. Educational workshops and hands-on training sessions introduced BSFL bioconversion techniques to local …

Green Design Of Plant Based Pharmaceutical Drugs: Example Of A Wound Healing Topical Cream With Plectranthus Bojeri (Benth) Hedge Lamiaceae Extract, Helga Rim Farasoa, Marie Louise Razafindravao, Rojo Fanambinantsoa Andriamiarantsoa, Gerard Cecilien Raboanary, Jean Marie Razafindrakoto, Voahangy Ramanandraibe Vestalys

Journal of Bioresource Management

To ensure the perennity of natural resources, the valorisation process of herbal pharmaceuticals must be assessed for sustainability from the very beginning of its design. No specific tools have been developed for this particular field so far. We demonstrate in this study that existing green design tools can be adapted to evaluate plant-based products manufacturing process. As the example of a topical cream using Plectranthus bojeri (Benth) Hedge LAMIACEAE extract was considered, we first confirmed the traditional use of this plant for wound healing. It acts by accelerating the re-epithelialisation phase. Using the Vermeer Cosmolife version 0.24 software tool the …

Metakaolin-Based Geopolymer Concrete; Synthesis, Development And Characterization, Heba Fouad

Theses and Dissertations

Geopolymers are rendered as an essential sustainable replacement to the widely used Ordinary Portland Cement (OPC) which causes immense carbon dioxide emissions, hence a detrimental impact on society’s health and the environment. Geopolymers are three-dimensional networks of polymerized tetrahedral silicate and aluminate in the form of Q4(4Al), Q4(3Al) and Q4(2Al) which act as the principal binding phase in concrete. Past research has reported the synthesis of geopolymers from different aluminosilicates precursors, their characterization, and their wide range properties. However, previous studies still have not properly investigated effective range of synthesis ratios for a particular source material, optimum curing regimes, short- …

Development Of The Principles Of Forming A Database For Geoinformation Mapping Of Tourism (As An Example Of Bostanlyk District Of Tashkent Region), Lola Xoji-Akbarovna Gulyamova, Risolat Raximjon Qizi Nizomova

Technical science and innovation

When creating tourist assessment maps for the purpose of tourist mapping, special attention is paid to determining the criteria for the formation of a database. To assess tourism opportunities in terms of natural conditions, ecology and socio-economic factors, data collection, their characteristics and requirements for them were studied. In order to improve the quality of sources of tourist assessment maps, parables of working with the internet and real-time removable data, creating a map based on social network data were considered. Proposals were made to create, manage and maintain a big data base. The ArcGIS program analyzed the possibilities of describing …

On Resource Testing Of Straight-Bevel Gears In Drive Mechanisms Of Cotton Machines, Shoraxmat Asqarovich Shaabidov, Umid Mamazokir Ugli Mamasobirov, Azizbek G‘Ulom O‘G‘Li Xusanbayev

Technical science and innovation

This article is dedicated to endurance testing of straight-tooth bevel gear reducers used in various machines, including cotton farming machinery. The choice of the test object is due to the fact that many machines require bevel gear transmissions for spatial arrangement of components. These gears enable the transmission of rotational motion between intersecting shaft axes within compact external dimensions. Additionally, bevel gear transmissions are the most common type of gear mechanisms after cylindrical ones.

For several objective reasons, straight-tooth bevel gears have gained wide use. Unlike cylindrical gears, they are more sensitive to manufacturing and assembly errors as well as …

End-To-End Autonomous Quadcopter Using Reinforcement Learning, Mohamed Marwan Chawa

Theses and Dissertations

This thesis investigates the potential of Reinforcement Learning (RL) for achieving robust and adaptable quadcopter control, focusing on trajectory and attitude stabilization. We compare state-of-the-art RL algorithms, specifically Proximal Policy Optimization (PPO), against traditional Proportional-Integral-Derivative (PID) controllers across three tasks: hovering, slow trajectory following, and fast trajectory following. To enhance realism, we employ a modified PyFlyt simulation environment with a high-fidelity Crazyflie 2.x model, accounting for motor dynamics, noise, wind disturbances, and aerodynamic drag.

The challenge of operating a quadcopter can be divided into two distinct parts: planning a flight path and actually following that path. Our focus is on …

Digital Twin And Cybersecurity In Additive Manufacturing, Lidong Wang

Journal of Cybersecurity Education, Research and Practice

Additive manufacturing (AM) has been applied to automotive, aerospace, medical sectors, etc., but there are still challenges such as parts’ porosity, cracks, surface roughness, intrinsic anisotropy, and residual stress because of the high level of thermal gradient. It is significant to conduct the modeling and simulation of the AM process and achieve quality products. Digital Twin (DT) can help AM with forecasting defects/errors through simulation and real-time process monitoring. DT is a concept of Industry 4.0, and its digital structure reflects the real-time behaviors of a cyber-physical or physical system. This paper introduces the progress of DT applications in AM, …

Determination Of The Kinetic Parameters Of Cholesterol Oxidation Using Cholesterol Oxidase From Streptomyces Sp., Meka Saima Perdani, Heri Hermansyah, Muhamad Sahlan, Dwini Normayulisa Putri, Teguh Pambudi, Anggi Khairina Hanum Hasibuan

Makara Journal of Technology

Cholesterol oxidase (CO) was successfully produced from Streptomyces sp. via the submerged fermentation method, and 69 U/mL enzyme activity was obtained. This study aimed to determine cholesterol oxidation kinetics and the production of CO as a catalyst. The enzyme was diluted to 0.15, 0.075, and 0.00375 U/mL for the oxidation reaction. The substrate was also prepared in three concentrations: 3.23, 6.46, and 12.93 mM. The optimization of conditions for enzymatic cholesterol oxidation was investigated through measurement of the effect of initial cholesterol and enzyme concentrations. Cholesterol concentration was rapidly measured via high-performance liquid chromatography (HPLC). The kinetics of CO were …

A Statewide Geographic Information System (Gis) As A Predictive Tool For Locating Deeply Buried Archeological Deposits In Nebraska: Phase Iii-The Sandhills Region, Anthony L. Layzell, Rolfe D. Mandel, John Swigart, David T. Williams

Nebraska Department of Transportation: Research Reports

This project developed a GIS to assist with the identification of deeply buried cultural deposits in alluvial settings across the Sandhills region of Nebraska. Soil survey data, previous geoarchaeological investigations, landform position, and other information was used to rank the potential of any stream valley setting as low, low-moderate, moderate-high, or high potential to contain buried cultural deposits. While the presence of buried soils does not necessarily translate to presence of buried archeological sites, the potential for such sites is far greater in buried soils. The GIS can be used by NDOT and other agencies with statutory historic preservation obligations, …

Movian: Advancing Human Motion Analysis With 3d Visualization And Annotation, Trudi Di Qi, Isaac Browen, David Zhang, Hector M. Camarillo-Abad, Franceli L. Cibrian

Engineering Faculty Articles and Research

Human motion analysis, including data visualization and annotation, is crucial for understanding human behavior and intentions during various activities, aiding in the development of innovative tools that support independent living. Current wearable sensing technology provides rich 3D spatial movement data but generates multimodal complex datasets that require specialized skills for effective analysis. Despite the need, limited research exists on tools for effective visualization and easy annotation of such complex motion data. MoViAn (Motion Data Visualization and Annotation) is an innovative 3D data analysis system offering enriched visual representations of 3D human motion data (e.g., gaze, hand movements), along with an …

Microwell Fabrication For Impedance And Ac Measurements Of Isolated Ventricular Cardiomyocytes, Fallon Wenck

Multidisciplinary Studies Theses and Dissertations

Electrophysiological behavior of human hearts have been extensively studied for hundreds of years. Even with elucidation of not just biological function, but also time and frequency-dependent current flow, the sheer intricacy of in vivo cardiac tissue function remains somewhat enigmatic. All while heart disease has been the leading cause of death in the United States for over a century, with its rates of occurrence still increasing annually [1]. Thus, new research techniques and tools to quantify cardiac function are still being pursued at smaller and smaller scales to decrease research/innovation time, cost, and diagnostic ambiguity. In fact, it remains incredibly …

Research On Latent Space-Based Anime Face Style Transfer And Editing Techniques, Haixin Deng, Fengquan Zhang, Nan Wang, Wancai Zhang, Jierui Lei

Journal of System Simulation

Abstract: To address issues such as image distortion and style uniformity in existing anime style transfer networks within the field of image simulation, we propose the TGFE-TrebleStyleGAN (textguided facial editing with TrebleStyleGAN) for anime facial style transfer and editing. This framework leverages vector guidance within the latent space to generate facial imagery and incorporates a detail control module and a feature control module to constrain the aesthetic attributes of the generated images. The images generated by the transfer network serve as style control signals and constraints for fine-grained segmentation. Text-to-image generation technology captures correlations between styletransferred images and semantic information. …

Mems 411: Timed Mosquito Egg Container, Daniel Nordquist, Preston Gee, Stephanos Mavrommatis

Mechanical Engineering Design Project Class

To aid in the war against mosquitoes, PHD candidate Lauren Johnson tasked this groups with developing a device to help study egg laying patterns. The goal is to create a device that can cut off access to tea water (an attractive breeding site) at specified time intervals in order to observe the effects of daylight and temperatures on mosquito egg laying behavior.

Measurement Of The Mechanical Properties Of Blood Vessels Using A Vascular Simulation Rig, Jack Lockyer

The Plymouth Student Scientist

Understanding the mechanical properties of blood vessels is crucial for reconstructive surgeons who connect donor tissue flaps to recipient sites. This paper describes the development of a vascular simulation test rig that delivers pulsatile flow to a blood vessel sample while continuously monitoring system pressure and sample diameter. These measurements allow for the calculation of the viscous coefficient, an important mechanical property for comparing blood vessels. A pilot test using the rig demonstrates its ability to measure pressure and diameter and highlights necessary improvements to enhance data quality. The pilot test shows that the current rig can measure 5 mm …

Effects Of Negative Poisson’S Ratio On The Mechanics Of Auxetic Carbon Fiber Composites Under Tensile, Buckling And Low Velocity Impact, Wenhua Lin

Dissertations - ALL

Carbon fiber reinforced polymer (CFRP) matrix composites exhibited superior properties, such as high specific stiffness and specific strength, excellent fatigue and corrosion resistance, and low coefficient of thermal expansion, have been popular across various industries including aerospace, marine, automotive, energy, civil infrastructure, and high-end sports over the past decades. However, one significant drawback of CFRP composites is the susceptibility to low velocity impact damage which, for aircraft, can be results of tool drop, runway debris, and bird strike during takeoff and landing. These impact events could lead to external and internal damages of a CFRP composite structure in various damage …

A Computational And Mathematical Approach To The Preclinical Development Of Alpha Emitting Radiopharmaceutical Therapies, Abdulaziz Said

McKelvey School of Engineering Graduate Student Theses & Dissertations

Numerous candidate nuclides have been undergoing rigorous preclinical development in the pursuit of novel targeted therapies. Successful development of these drugs relies on the understanding of physiological impacts at the macro and micro scales, in addition to a scalable process for their production. Here, mathematical and computerized approaches have been developed to guide this preclinical development. In this report, two alpha emitting nuclides Pb-212 and Ra-223 are modeled. Radium-223 dichloride citrate a newly approved ion indicated for treatment of bone metastatic castrate resistant prostate cancer, irradiates lesions through targeted uptake in bone at sites of disease. We have undertaken the …

Optimization Of Tps Films Using An Adaptive Design Of Experiments Approach In A Bayesian Optimization Framework, Theresa Marks, Gracie White, Scott Lohman, Mayank Malhotra

The Journal of Purdue Undergraduate Research

Plastic pollution, amounting to 12 million tons annually, necessitates sustainable alternatives to single-use plastics. Compostable thermoplastic starch (TPS) films show promise but lack strength and durability compared to traditional plastics. This study employs an adaptive design of experiments (DoE) approach to enhance TPS films by optimizing testing points. The research focuses on varying concentrations of plasticizers (acetic acid and glycerol) in a water and potato starch mixture, aiming to identify the optimal ratio maximizing tensile strength and % elongation at break. Gaussian process regression (GPR) with uncertainty estimation and Bayesian optimization (BO) utilizing an acquisition function (AF) are employed. The …

A Comparison Of Rfssw And Rsw For Automotive Manufacturing, Damon Michael Gale

Theses and Dissertations

Historically, automotive body panels have been made of steel and joined by a process called resistance spot welding (RSW). However, in efforts to reduce vehicle weight to improve the energy efficiency of the vehicle, automotive manufactures have begun substituting aluminum in place of steel. While aluminum can be joined with RSW, a myriad of challenges arise from doing so. These challenges result in less consistent weld quality and accelerated electrode wear. Refill friction stir spot welding (RFSSW) is an emerging joining technology that could replace RSW as it is believed to be capable of creating superior joints in thin sheet …

Design & Development Of Fr1 Band Antenna For V2x Communication, Sujanth Narayan Kg

Theses and Dissertations

The developing trends in the automotive industry are evolving towards connected and autonomous vehicles that provide various advantages namely enhanced safety & security, congestion less traffic, smart mobility, and environmental sustainability at a lower cost with greater cause to the society. Vehicle to Everything (shortly V2X) Communication plays a significant role in autonomous driving. Salient features of V2X provide improved better driving experience and traffic efficiency even during fast moving scenarios.

V2X technologies are being carried out in sub 6 GHz range mainly at the 5.9 GHz band called the Dedicated Short-Range Communication (DSRC) based on IEEE 802.11p providing support …

Targeting Myeloid Cell Iron Metabolism In Salmonella-Induced Colitis, Mariella Arcos Padilla

Biomedical Engineering ETDs

Salmonellosis is a severe infection caused by Salmonella enterica serovar Typhimurium, leading to significant global morbidity and mortality.

Previous studies have shown that mice lacking the iron storage protein ferritin heavy chain (FTH1) in myeloid cells exhibit worsened Salmonella infection. Nuclear receptor co-activator 4 (NCOA4) directs FTH1 autophagic degradation to release iron from storage during conditions of low iron. However, the role of myeloid NCOA4 in regulating bacterial infections remains unclear.

Here, we found that myeloid NCOA4 deficiency augments spleen iron levels and increases cellular iron accumulation, oxidative stress, and ferroptosis in bone marrow-derived macrophages (BMDM) cells. This deficiency also …

Rational Design Of Nanoparticles For Overcoming Barriers Of Nucleic Acid Delivery: Applications In Cancer Therapeutics, Angelea M. Maestas-Olguin

Chemical and Biological Engineering ETDs

The use of exogenous nucleic acid technologies to modulate aberrant protein expression resulting from genetic mutations is a promising therapeutic approach for the treatment of diseases such as cancer. The promise of nucleic-based therapeutics is dependent on the development of platforms that effectively protect nucleic acids from nuclease degradation and deliver the nucleic acids to specific intracellular locations (nucleus or cytosol) of target cells. The application of nanotechnology for development of nucleic acid-based nanomedicines is poised to revolutionize the clinical landscape of cancer. In this dissertation, I demonstrated the rational design, synthesis and evaluation of a lipid coated mesoporous silica …