Digital Commons Network^™

Metal Oxide Nanoparticle‑Integrated Phema Hydrogels: Morphology, Chemical Properties, And Biological Interaction, Venkateswar Rao, Collin Cox, Brandon Clark, Arushi Rai, Erick S. Vasquez-Guardado, Madhuri Kango-Singh, Soubantika Palchoudhury

Chemical and Materials Engineering Faculty Publications

Hydrogels offer attractive matrices for incorporating inorganic metal oxide nanoparticles (NPs) to generate multifunctional hybrid materials, but challenges remain in scalable synthesis and correlating their properties to bio-interaction. Therefore, we report the synthesis and characterization of poly(2-hydroxyethyl methacrylate) (pHEMA) hydrogels, and pHEMA hydrogels encapsulating iron oxide or zinc oxide NPs, using a modified free-radical polymerization. Dose-dependent survivorship studies on Drosophila melanogaster revealed that both NP-embedded hydrogels are tolerated over a wide dose range (e.g., 50–200 mg), although ZnO NP-gels exhibit lower survivorship at some concentrations due to their inherent composition and a wider size distribution of iron oxide NPs.

An Integrated Sensor-Fusion Framework For Performance-Based Compensation In Construction, Aly Ayman El-Ashry

Theses and Dissertations

Construction productivity has historically stagnated due to a reliance on subjective labor monitoring and “lagging” performance indicators. This research proposes a novel compensation model with the use of Total Energy Management System (TEMS) to translate labor effort and efficiency into payment incentives with the integration of Internet of Things (IoT) wearables and Statistical Process Control (SPC) charts.

This research addresses the systemic problem of declining construction productivity caused by industry’s inability to objectively quantify human effort. While traditional models rely on post-facto production tallies, a significant research gap exists in real-time physiological labor monitoring. To bridge this, the proposed TEMS …

Evaluating C-Band Scatterometer Images For Estimating Deforestation In The Amazon Rainforest, Alex Mcbride

Theses and Dissertations

Satellite-based active microwave sensors have been successfully employed for a wide range of vegetation and soil studies. Spaceborne microwave instruments have proven particularly useful for wide-scale monitoring of the vegetation, especially under conditions that limit the effectiveness of high-resolution optical sensors. Satellite scatterometry can be used to detect and model deforestation in the Amazon rainforest by correlating changes in the C-band backscatter data to observed changes in vegetation coverage. The exploratory methodology developed in this paper applies the longest continuous microwave satellite record to the problem of deforestation. The backscatter measurements taken by the ERS and ASCAT missions provide more …

Foundations' Deep, Emily Williams, Morgan Williams

University Honors Theses

Most historic buildings do not survive as they were built, yet preservation frameworks still tend to evaluate them as if they did.

Foundations' Deep begins with a structure located in Helena, Montana 59602, a building that sits uneasily within the categories it has been asked to meet. Built in the early twentieth century, it has persisted through alteration, abandonment, and use. What remains is not a stable artifact but a record of accumulated decisions, some careful and many indifferent, now embedded in the fabric of the building itself.

The thesis grows from this condition and from the limits of the …

Declination Of Groundwater Potential Zones Of Nashik, Maharashtra Using Geographic Information System With Analytic Hierarchy Process-Fuzzy Techniques, Madhusudhan M. Reddy, Bhogayya G. Naidu, Bharat N. Mulay, Ramanjaneyulu B, Ravi K. Kumar, Mirzi L. Betasolo, Praveen U. Goud, Snehal N. Chaudhari

Mansoura Engineering Journal

Groundwater is a critical resource for agriculture and domestic use in the semi-arid region of Nashik District, Maharashtra, where overexploitation and erratic climatic conditions have led to declining groundwater availability. This study integrates Geographic Information System (GIS) with Analytic Hierarchy Process (AHP) and Fuzzy-AHP techniques to delineate groundwater potential zones (GWPZs) and identify suitable sites for artificial recharge. A total of ten thematic layers drainage density, rainfall, geomorphology, elevation, distance from river, geology, slope, land use/land cover, topographic wetness index (TWI), and curvature were derived from SRTM DEM, Landsat-8, and IMD datasets, representing key controls on groundwater recharge, infiltration, and …

Bilingual Math For Kindergartners (Biki), Anna Aldrin, Caroline Tapia, Lillian Le

Computer Science and Engineering Senior Theses

For many children from bilingual households, kindergarten represents a critical, learning benchmark where the introduction of fundamental math concepts coincides with their first significant exposure to the English language. Traditional educational methods often fail to support English language learners, leading to a disconnect between their understanding of math in the home and its application in the classroom. This linguistic barrier frequently results in reduced engagement, diminished confidence, and an unstable educational foundation that can discourage students from pursuing STEM careers later in life. While existing platforms like Khan Academy and Duolingo address either language acquisition or mathematical proficiency independently, they …

Maya Roots, Erin Schmidt, Megu Kanzawa

Computer Science and Engineering Senior Theses

This project focused on the continued development of Maya Roots, a mobile and web-based platform designed for farmers in Tahcabo: a rural agricultural community located in Yucatán, Mexico. Yucatán faces unique agricultural challenges due to its karst limestone terrain and highly variable land conditions that can significantly impact farming outcomes. At the same time, traditional agricultural knowledge such as Milpa farming practices is increasingly at risk of being lost across generations. These environmental and cultural challenges highlighted the need for a portable, accessible system that could preserve agricultural knowledge, improve access to geospatial information, and strengthen communication between farmers and …

Investigations Of Carbon Dioxide Storage In Low-Temperature Reservoirs For Non-Leaking Storage, Md Nahin Mahmood

Doctoral Dissertations

Carbon dioxide (CO₂) injection into subsea or low-temperature water zones has emerged as a promising strategy for long-term, non-leaking CO₂ storage through the formation of solid hydrates. This research investigates CO₂ injection into Berea sandstone cores saturated with water under simulated subsea conditions, focusing on hydrate formation behavior across varying temperatures, pressures, and injection flow rates. Experimental results demonstrate that CO₂ hydrate formation under dynamic (flowing) conditions occurs at significantly higher pressure compared to static conditions reported previously. At temperatures ranging from 0 °C to 5 °C, dynamic hydrate formation pressures were observed to be approximately double. This can be …

A Simulation-Based Lean Six Sigma Framework For Process Optimization In Textile Manufacturing Toward Industry 4.0, Md Shafiqul Islam Chowdhury

Masters Theses

This study focuses on integrating simulation modeling with Lean Six Sigma (LSS) within the DMAIC (Define, Measure, Analyze, Improve, Control) framework for process optimization in textile manufacturing industry. Although traditional LSS framework such as Value Stream Mapping (VSM) and Root Cause Analysis are effective in identifying waste, they mainly rely on static and historical data which make their capability limited for real analysis or predictive decision making. As a result, many textile manufacturing processes still face challenges such as production delays, excessive work-in-process (WIP), high cycle time, and inefficient resource utilization. To address this issue, this research proposes a simulation-based …

Test Bench Pcb Design For A Vlsi Grid Cell Chip, Nicholas Bruk, Jason Alexandar

Electrical Engineering

This report presents the design, implementation, and validation of a custom printed circuit board (PCB) test bench for a VLSI grid cell emulation chip. The final board provides two independently adjustable 5V supplies using LM317 linear regulators, eleven potentiometer-controlled bias voltages, high-impedance buffering of analog outputs via an MCP6022 dual operational amplifier, and buffering of digital outputs using a 74HC244 buffer IC. The design includes a 40-pin DIP socket for the VLSI chip, extensive test-point headers for probing, and a 9V battery input for portable operation. Five fully functional boards were fabricated using ExpressPCB and assembled with through-hole components. An …

Wildlife Tracking Via Uav&Rf, Nam Ah Nguyen

Electrical Engineering

Animal tracking collars transmit very-high-frequency (VHF) beacon signals so researchers can locate tagged wildlife in terrain where direct visual tracking is difficult. This project develops a radio-frequency (RF) wildlife tracking prototype in which a UAV carries a receiving antenna and receiver over the search area to detect the collar signal and send measurements to a ground station. A transmitter test device was built to emulate a tracking collar. An STM32 microcontroller reads keypad input, controls a digital-to-analog converter (DAC), tunes a voltage-controlled oscillator (VCO) to the selected VHF frequency, and sends the RF signal through an amplifier and antenna. The …

Pv Performance Evaluation Study At Cal Poly Solar Farm, Eva Paola D. Calderon

Electrical Engineering

This photovoltaic (PV) system performance evaluation study aims to assess the performance of Cal Poly’s Gold Tree Solar Farm, which produces 4.5MW of solar energy. The evaluation concerns itself with the reliability of the PV system that can be affected by weather conditions, component malfunctions, and degradation of the PV modules. Under the International Energy Agency Photovoltaic Power Systems (IEA-PVPS) Task 13 objectives of reliability and maintenance, this study is necessary to contribute towards improvements in analysis and mitigation strategies for long term usage. Existing operational monitoring data from 2018 to 2025 is the focus timespan, providing real world data …

Trim-Transfer: A Transfer Learning Approach For Cross-Trim Level Can Intrusion Detection, Baylor J. Whitehead

Master's Theses

Modern vehicles contain many Electronic Control Units (ECUs) that communicate through CAN. While CAN enables efficient data communication, it lacks built in authentication and encryption, allowing adversarial actors to inject malicious CAN messages. This limitation has motivated the development of CAN intrusion detection systems (IDS). However, deploying IDS across a vehicle lineup requires collecting large labeled datasets and retraining models, increasing development cost and limiting scalability.

This thesis investigates the use of transfer learning with LSTM-based deep neural networks to reduce retraining cost while maintaining model detection performance. A baseline LSTM model is trained using CAN data from a base …

Collagen Gene Expression Is Linked To Aging And Lifespan Extension In C. Elegans, Archer J. Wang, Blake M. Geppert, Daniel Beck, Yanqing Ji, Yiyong Liu

Electrical & Computer Engineering Faculty Scholarship

Collagens, long regarded as structural molecules, also regulate stress responses and longevity. In this study, we analyzed our RNA sequencing data and publicly available gene expression data to define their role in Caenorhabditis elegans aging. Collagen expression broadly declined with age, with 16 collagen genes consistently downregulated across independent studies, establishing collagen downregulation as a genetic hallmark of aging. In contrast, meta-analysis of 66 datasets (128 comparisons between normal and long-lived animals) showed collagen upregulation in 84% of long-lived conditions, identifying collagen induction as a conserved signature of lifespan extension. Using π-values to integrate fold change and significance of …

Evaluation Of Alternative Solvents For Electrospinning Occluded Scaffolds To Model Intracranial Atherosclerotic Disease In Blood Vessel Mimics, Olivia D. Rankin

Master's Theses

Intracranial atherosclerotic disease (ICAD) is characterized by a buildup of fatty plaque within the walls of arteries supplying the brain, resulting in vessel narrowing, restricted blood flow, and increased risk of ischemic stroke. While various treatments exist for ICAD, most are accompanied by high recurrent stroke rates and other adverse events, highlighting the need for further investigation and models for pre-clinical testing. Tissue engineered Blood Vessel Mimics (BVMs), consisting of a polymer scaffold sodded with human vascular cells, serve as physiologically relevant in vitro models for vascular device testing. This thesis focused on the application of alternative solvents to a …

Robotic-Assisted Pedicle Screw Placement Achieves High Accuracy And Narrows The Experience Gap: A Preclinical Evaluation, Anna T. Reza, Matthias Walper, Mitchell K. Ng, Paul G. Mastrokostas, Andrew S. Lee, Rafael G. Rafael, Kornelis A. Poelstra, Ratliff K. John, Rajiv K. Sethi, Michael A. Mont

Rothman Institute Papers

To assess a robotic-assisted system versus open manual techniques to: (1) compare pedicle screw accuracy between fellows and attendings with and without robotic assistance, and (2) evaluate executed versus planned trajectory fidelity relative to prior reports. Robotic-assisted spine systems aim to improve the accuracy, reproducibility, and safety of pedicle screw placement. Limited evidence compares outcomes across differing surgeon experience levels. A total of 255 thoracolumbar pedicle screws were placed in synthetic torsos simulating adult degenerative anatomy. Four surgeons (two fellows, two attendings) each placed half their screws using open fluoroscopy-guided techniques and half using a minimally invasive percutaneous approach with …

Custom Animatronic Puppet, Jake Schuman, Fredy Herrarte, Madison Reedy, Jackson Reynolds

Mechanical Engineering

This project involved the design, fabrication, and implementation of a custom audio-animatronic puppet modeled after Dr. Brian Davis for the California Polytechnic State University Mechanical Engineering Department. The objective was to create an expressive, lifelike character capable of synchronized speech, head movement, arm gestures, and seated-to-standing motion while demonstrating the integration of mechanical design, controls, manufacturing, and artistic fabrication.

The final system consists of an 18-degree-of-freedom animatronic platform utilizing servo-driven facial and upper-body actuation combined with a pneumatic standing mechanism. A modular aluminum and 3D-printed structural framework was developed using SolidWorks and validated through engineering analysis. Character shells were digitally …

Xylem: A Comparative Analysis Of Gpu Dispatch Pipelines For Large-Scale, Procedural Environments, Srinivas Sundararaman

Master's Theses

The real-time rendering of large-scale, procedural scenes presents a significant performance challenge for traditional CPU-bound rendering pipelines. The high volume of draw calls and the need for complex culling and level-of-detail management create bottlenecks that limit scene complexity and visual fidelity. This thesis investigates the evolution of GPU-driven rendering paradigms via the Xylem renderer within NVIDIA’s Donut rendering framework as a solution to these challenges.

A comprehensive benchmarking framework is developed to implement and quantitatively analyze three distinct rendering strategies for a procedurally generated, parameterizable, large-scale forest scene. The evaluated pipelines include: (1) traditional instanced rendering, (2) compute-driven indirect rendering …

Pet Mobility Project, John Shelby, Lily-Rose Jolie Bacon, Andrea Yasmine Reyes

Biomedical Engineering

The Pet Mobility Project, sponsored by Terri Smith and Jasper Jackson, is an initiative aimed at providing a custom mobility aid to a pet in the San Luis Obispo community. Amber Rappozo’s young German Shepherd, LeDoux, was selected as the project’s recipient. LeDoux suffers from hindleg weakness and, as a result, has limited mobility. This document provides a comprehensive overview of the Pet Mobility Project, detailing the motivation, background, and design approach behind the development of a LeDoux’s custom mobility aid.

Cardiac Twitch Force Measurement System, Tara Hoffman, Sebastian Carrascal Gómez, Julian Macdonald

Biomedical Engineering

The goal of this project is to develop a low-cost and accurate force measurement system and method of measurement to be used in the testing of grown cardiac tissue samples. The primary stakeholder in this project is Dr. Luke Perreault, a biomedical engineering professor at California Polytechnic State University San Luis Obispo who is studying grown cardiac tissue rings, and any of his student lab personnel. Other stakeholders include other researchers in the tissue engineering field who require a similar form of testing to the methods developed in this project.

This document will introduce the identified problem and background as …

Pcb Design For Place Cells Vlsi Chip, Gavin Reaksecker, Alex Krier, Joshua Lin

Electrical Engineering

This project presents the design and implementation of a 2 layer test-bench printed circuit board (PCB) for evaluating the functionality of a custom 40-pin VLSI integrated circuit. The objective is to create a reliable and portable platform capable of supplying configurable bias voltages, generating variable input signals, and monitoring both analog and digital outputs. The board integrates adjustable bias networks using potentiometers, digital and analog buffering stages, and optional battery supply operation. The VLSI device under test is mounted in dual-in-line (DIP) sockets to enable rapid replacement and repeated characterization. Dedicated test points are incorporated throughout the PCB to facilitate …

Integration Of Robotic Arm And Conveyor With Programmable Logic Controller, Drake A. Small

Master's Theses

To meet new curriculum demands brought on by Cal Poly's upcoming switch to semesters, a new, cross-disciplinary lab module was developed for EE 435 (Industrial Power Control and Automation). The module emphasizes career-applicable skills, preparing students for the field of controls engineering within the manufacturing industry. These skills include robotic control, computer networking and configuration, and embedded systems. The work focused on integrating a collaborative robot arm to pick-and-place boxes on a conveyor. A myCobot 320 Pi and an Ultimation Powered Roller MDR Conveyor were integrated with the existing PLC system using Modbus RTU and EtherNet/IP communication protocols, respectively. A …

Tanzania Mbesese Initiative 2026, June Ezzell, Sam Liebman, Noah Beyer, Kate Hamilton, Luke Vollert, Kylee Borgen, Cody Balazs, Meg Mclaughlin

Architectural Engineering

The Tanzania Mbesese Initiative 2026 Senior Project supports a multi-year design-build effort to establish the Same Polytechnic College in Same, Tanzania. This community faces high poverty levels and limited access to higher education, necessitating sustainable infrastructure to support tertiary education. To prepare for the upcoming July phase of construction, an eight-student Architectural Engineering team designed three practical and resilient structures: a Shade Structure, a Water Collection Structure, and a Reusable Scaffolding system. The final design applied structural analysis, modeling, and hand-tool fabrication practice to balance material efficiency with long-term structural durability. The deliverables provide comprehensive construction documentation, complete material takeoffs, …

Evaluation Of Laser Doppler Flowmetry And Transillumination Laser Speckle Contrast Imaging To Measure Blood Flow Change In Ischemia Mouse Hindlimb Models, Simon Park

Master's Theses

Peripheral Artery Disease (PAD), caused by plaque buildup and narrowing of the arteries, reduces blood flow to the extremities. Promoting collateral arteriogenesis can help redirect blood flow. However, simple growth of collaterals may not be enough to reverse PAD. Instead, the ability for the collaterals to vasodilate and control blood flow is important, meaning assessing collateral function is important for the arteriogenesis assesment. Although microscopy techniques can measure vasodilation, contrast limitations in larger vessels such as collaterals make blood flow measurements difficult. Techniques such as ultrasound or magnetic resonance imaging (MRI) can measure blood flow but have limitations with cost …

Polysaber: A Custom Reactive Lightsaber Soundboard, Pedro B. Medeiros

Computer Engineering

The PolySaber project was developed as a custom reactive lightsaber control system built as a fully custom PCB design. The purpose of the project was to create a lower-cost and more customizable alternative to commercially available lightsaber soundboards while simultaneously providing hands-on experience in PCB design, embedded systems development, and hardware integration. Commercial lightsaber soundboards are expensive, proprietary, and difficult for hobbyists to customize. The PolySaber project addresses this by creating a modifiable hardware platform built around the ESP32 microcontroller. The system supports programmable firmware, RGB NeoPixel blade control, motion sensing, reactive swing and clash effects, onboard audio amplification, and …

Off-Grid Cabin Hydroelectric Generator, Keller Feltman, Lance Savatgy, River Perino, Jesse Valencia

Mechanical Engineering

This project developed a portable hydroelectric generator intended to provide low-power electricity generation for an off-grid cabin in Alpine County, California. The system was designed to utilize naturally occurring creek flow to generate electrical power while remaining portable, durable, and environmentally conscious.

The final system consists of an axial-flow turbine, belt-driven generator subsystem, waterproof electronics enclosure, aluminum support frame, and integrated wildlife protection screening. Engineering analysis was performed to estimate hydraulic power availability, turbine performance, drivetrain requirements, and component lifespan. These analyses guided the selection and development of the final design.

Throughout prototype testing, several design modifications were required. Initial …

Computational Modeling To Evaluate Bipolar Flexible Electrode Designs For Use In Sciatic Nerve Stimulation, Krystyna S. Allman

Master's Theses

Peripheral nerve stimulation is clinically used to manage pain, rehabilitate motor function, and promote nerve regeneration. The sciatic nerve is often studied for stimulation due to its accessibility and clinical relevance. A conventional nerve cuff electrode is the least invasive method for nerve stimulation, but the mismatch of mechanical properties of the electrode with the nerve tissue can cause damage to the nerve and the electrode itself. This study investigated a novel bipolar, gold nanowire-based cuff electrode design and its ability to selectively activate fibers in the rat sciatic nerve at varying interelectrode spacings. In COMSOL, A finite element model …

Sheep Pen Improvements At City Farm Slo, Diego Eliseo Romero

Construction Management

City Farm SLO is a non-profit educational farm that focuses on creating clean produce and educational farm work environments in San Luis Obispo, California. The farm can provide its community with learning programs for the youth, hands-on experience in farming practices, and livestock care. The work was set out for this project across two quarters where we improved the existing sheep pen so that the volunteers and livestock who use the pen can enjoy the area much more comfortably and safely. The overall project scope included several improvements which all required initial designs, coordination with the farm and its volunteers, …

Sheep Pen Improvements At City Farm Slo, Rylan Joseph Hickman

Construction Management

This project took place on a non-profit community farming space called City Farm SLO which provides opportunities for local small scale independent farmers to farm and provide crops to the community. Our project provided improvements to the livestock pen that they have on the farm which is home to chickens and a flock of sheep. The main goal of this project was to provide a better living environment for the sheep including a 50 cubic yard sheep hill, a vehicle access gate, a side gate, a front catch pen, a back corral, and protective fencing for a guava tree. Within …

Design And Characterization Of A Pulsed Electric Field Chamber For Microalgae Lysis, Connor Strutin

Electrical Engineering

Microalgae are a promising renewable source of biofuel due to their high lipid content and rapid growth rates; however, algae cells must be electroporated (lysed) to release these lipids. The system developed in this project applies short (40 μs–10 ms), high-intensity (up to 33 kV/cm) pulsed electric fields (PEF) across cell membranes to enable electroporation.

Our lab-scale PEF chamber generates uniform, high-intensity electric fields using parallel-plate electrodes with sub-millimeter spacing. The system is designed to efficiently lyse microalgae cells for lipid extraction and biofuel production.