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Full-Text Articles in Entire DC Network
Measuring Welfare Of Wild Tarantulas During Field Surveys Using Heart Rate, Tim Angelo Artiaga Lopez, Becky Hansis-O'Neill, Aimee Dunlap Phd
Measuring Welfare Of Wild Tarantulas During Field Surveys Using Heart Rate, Tim Angelo Artiaga Lopez, Becky Hansis-O'Neill, Aimee Dunlap Phd
Undergraduate Research Symposium
Tarantulas (Theraposidae) are predatory arachnids that can help control populations of herbivorous arthropods. We have been monitoring populations of the Missouri brown tarantula (Aphonopelma hentzi) in Missouri glades for three seasons and have questions about their welfare during these surveys. Unlike mammals, arthropods are not extensively researched and there are only a few known facts about measuring their welfare. Managing stress for wild animals during field surveys is important for reducing the potential negative impacts of research. In mammals, increased heart rate is positively correlated with negative stress and eustress. Using the same logic, we hypothesized that heart rate could …
Habitat Disturbance And Biodiversity In Glade Habitats, Maddie Smith, Becky Hansis-O'Neill, Aimee Dunlap Phd
Habitat Disturbance And Biodiversity In Glade Habitats, Maddie Smith, Becky Hansis-O'Neill, Aimee Dunlap Phd
Undergraduate Research Symposium
The Ozark glades are home to a variety of reptiles, amphibians, rodents, and invertebrates such as tarantulas and scorpions. Glade inhabitants face challenges like habitat fragmentation and degradation, but they could be facing even bigger challenges as outdoor recreation becomes more popular. People looking for wildlife to photograph or collect often look under rocks without leaving them how they were found. This study focused on monitoring rock disturbance at two protected glades- Shaw Nature Preserve and a more accessible undisclosed glade in Jefferson County. Disturbing the glade habitat to look for wildlife is prohibited at both sites. Twenty rocks at …
Indigenizing Aquaculture: In Pursuit Of An Integrated Multi-Trophic Aquaculture System For Enhanced Self-Sufficiency In Akaroa Harbour, Aotearoa New Zealand, Cali R. Trainor
Capstone Collection
This study assessed the feasibility of integrating two pre-existing aquaculture activities in Akaroa Harbour, Aotearoa New Zealand into an integrated multi-trophic aquaculture (IMTA) system. The cultivation of giant kelp (Macrocystis pyrifera) presents an opportunity to improve the sustainability of Chinook salmon (Oncorhynchus tshawytscha) farming by introducing alternative food sources for salmon, which can be used to produce fish feed locally, enhancing the self-sufficiency of the community and boosting the holistic efficiency of the system. Macroinvertebrates residing in giant kelp wrack were collected, identified, and quantified to determine if any of the Macrocystis-associated specimens could serve as …
The Role Of Attention And Design In The Effectiveness Of Eco-Feedback Systems, Lyndsey Bentzoni
The Role Of Attention And Design In The Effectiveness Of Eco-Feedback Systems, Lyndsey Bentzoni
Best Integrated Writing
This paper examines the role of eco-feedback systems in promoting pro-environmental behaviors by providing users with easily accessible information about their resource consumption. While these systems have shown potential to reduce consumption, they can face difficulties in maintaining user engagement and achieving long-term behavior change. There are several key factors related to the design of feedback interfaces that influence the effectiveness of eco-feedback systems. Gamification has been proposed as an effective way to enhance user engagement but requires careful design to connect behaviors from the digital to the real space for learning transfer. Research on the long-term usage of these …
Modeling The Mojave: A Multiphase, Mixed Methods Phenomenological Investigation Of Novice Understanding Of A Complex Ecological System, Nicole Juliana Thomas
Modeling The Mojave: A Multiphase, Mixed Methods Phenomenological Investigation Of Novice Understanding Of A Complex Ecological System, Nicole Juliana Thomas
UNLV Theses, Dissertations, Professional Papers, and Capstones
This research explores early college science majors’ conceptions of the Mojave Desert ecosystem as a complex system. A multi-level, explanatory sequential mixed methods design was employed to study college science majors’ understanding of the Mojave Desert ecosystem to better inform science pedagogy. The first level, the quantitative phase of the study, consisted of developing a mathematical representation of twelve ecosystem variables present within the Mojave Desert. The second level, the qualitative phase of the study, consisted of phenomenological semi-structured interviews with 23 early college science majors. The findings of this research suggest that the Mojave Desert operates as a complex, …
Enviromental Dna (Edna) Tools For Invasive Mosquitofish (Gambusia Affinis) Surveillance At The Shoshone Pupfish (Cyprinidon Nevadensis Shoshone) Refugium, Yusuf Olamilekan Umar
Enviromental Dna (Edna) Tools For Invasive Mosquitofish (Gambusia Affinis) Surveillance At The Shoshone Pupfish (Cyprinidon Nevadensis Shoshone) Refugium, Yusuf Olamilekan Umar
UNLV Theses, Dissertations, Professional Papers, and Capstones
Spring-fed aquatic ecosystems of the North American Southwest and U.S. Great Basin hosts a plethora of endemic fish species due to the effects of hydrologic fragmentation that resulted from Pleistocene aridification. Threats to endemic fishes worldwide include human intentional or unintentional release of exotic species into their habitats. Early detection of invasive species, while corrective actions are still possible, is critical for management, yet traditional survey methods are often disruptive to sensitive ecosystems, costly, and limited in sensitivity. The recent development of environmental DNA (eDNA) approaches offers powerful alternatives for invasive species monitoring in aquatic systems. In this study, a …
Variation In Nectar Rewards Under Water Limitation Across Flowering Species, Madeline Isabelle Gregor
Variation In Nectar Rewards Under Water Limitation Across Flowering Species, Madeline Isabelle Gregor
Undergraduate Honors Theses
Drought is becoming an increasingly dominant force shaping plant–pollinator interactions, yet we still know little about how nectar rewards respond to water limitation across species commonly used to support pollinators. We examined nectar volume and sucrose content in six flowering species relevant to California’s Mediterranean climate and quantified how drought alters these traits for four of those species. Under well-watered conditions, species differed in their nectar production, spanning more than two orders of magnitude. Perennial species such as Epilobium canum and Scrophularia californica produced the highest nectar volumes and sucrose amounts, suggesting that they contribute substantial carbohydrate resources when moisture …
An Updated Annotated Checklist Of The Mammals Of The Crane Trust, Hall County, Nebraska, Bethany L. Ostrom, Amanda H. Medaries, Andrew J. Caven, Jenna M. Malzahn, Alexa Rojas, Matthew R. Schaaf, David M. Baasch, Thomas E. Labedz, Greg D. Wright
An Updated Annotated Checklist Of The Mammals Of The Crane Trust, Hall County, Nebraska, Bethany L. Ostrom, Amanda H. Medaries, Andrew J. Caven, Jenna M. Malzahn, Alexa Rojas, Matthew R. Schaaf, David M. Baasch, Thomas E. Labedz, Greg D. Wright
Transactions of the Nebraska Academy of Sciences and Affiliated Societies
The Crane Trust is a regional nonprofit conservation organization that has protected land in the biologically important Central Platte River Valley for over four decades. A mammal inventory was conducted on the Crane Trust’s main habitat complex in 1980. Since, a variety of environmental conditions have shifted locally, regionally, and globally. An analysis of the mammal community was conducted using past and recent data to determine how species composition and relative abundance have shifted categorically from 1980 to 2021. We used all available data to categorize relative abundance during two distinct time periods per a modified “DAFOR” scale including 7 …
The Nebraska Bird Review (December 2025) 93(4), Whole Issue
The Nebraska Bird Review (December 2025) 93(4), Whole Issue
Nebraska Bird Review
Changes to The Nebraska Bird Review, by Janis Paseka
Fall Field Report, August–November 2025, by W. Ross Silcock
First definitive records of Hermit Thrush and Wilson’s Warbler subspecies for Nebraska, by Stephen J. Brenner and Joel G. Jorgensen
Ogallala Fall Field Days, Sept. 26–28, 2025
Index to Volume 93
Subscription and Organization Information
Index To Volume 93
Nebraska Bird Review
Adams, Morgan
Aguiar: Maritza, Stephanie
Albright, Don
Alexander: Jeff, Jan
Aliferis, Taylor
Allard, Savannah
Allen, Edward
Allison, Betty
Altman, Dakota
Alvarado, A. H.
Ammon, E. M.
Anandan, Sampath Kumar
Andersen, Brett
Anderson: Ann, Chris, Will
Andrews, Ryan
Anhinga
Ani, Groove-billed
Annunziata, Laura
Armstrong, Nancy
Augustine, Jackie
Aurilio, James
Avocet, American
. . .
Zagst: Fred, Kay
Zeillemaker, Fred
Zemaitis, William
Zicafoose, Kirby
Zonotrichia leucophrys: gambelii, leucophrys, oriantha
First Definitive Records Of Hermit Thrush And Wilson’S Warbler Subspecies For Nebraska, Stephen J. Brenner, Joel G. Jorgensen
First Definitive Records Of Hermit Thrush And Wilson’S Warbler Subspecies For Nebraska, Stephen J. Brenner, Joel G. Jorgensen
Nebraska Bird Review
During the fall of 2025, we initiated a pilot migratory bird-banding project in the Nebraska Panhandle. While the project’s goals included examining species composition, volume, and body condition of migratory birds at the western edge of the state compared to the eastern edge of the state, we also used this project to document the occurrence of subspecies and species which are very challenging or impossible to identify through field observation. Here, we report on the first definitive records of two subspecies in Nebraska.
On 16 September 2025, SJB banded an adult male Wilson’s Warbler (Cardellina pusilla) that was …
Fall Field Report, August–November 2025, W. Ross Silcock
Fall Field Report, August–November 2025, W. Ross Silcock
Nebraska Bird Review
As in previous fall seasons, by far the most modifications to BONO came from late departure dates; around 87 species were included, no fewer than 13 of these setting record late dates, notably Eastern Whip-poor-will, Mountain Plover, Brown Thrasher (north), Henslow’s Sparrow (flight call only), and Orchard Oriole.
Although this is a Fall Seasonal Report, noted or suggested breeding activity is of interest. Exciting were the 2nd and 3rd presumed breeding records of Black-chinned Hummingbird and, in Dodge Co, the 5th record of breeding by Black-bellied Whistling-Duck. Perhaps the strangest west to east occurrence was a Golden Eagle adventure in …
Changes To The Nebraska Bird Review, Janis Paseka
Changes To The Nebraska Bird Review, Janis Paseka
Nebraska Bird Review
As of this issue, The Nebraska Bird Review has been in existence for 93 years, looking very much now as it did when it began in 1933. However, due to the increasing costs of printing and postage, there will be some changes in its future. Our newsletter, The Burrowing Owl, is already provided online to our members, in a user-friendly and informative form. Future issues of The Nebraska Bird Review will also utilize a digital format to offer a more timely and colorful publication.
This is the final issue for which Ross Silcock will be compiler of the seasonal …
Ogallala Fall Field Days, Janis Paseka
Ogallala Fall Field Days, Janis Paseka
Nebraska Bird Review
The 2025 NOU Fall Field Days were held in Ogallala on September 26–28, with about 80 in attendance. The programs were held at the Quality Inn, and the meeting was planned by Boni Edwards, Dave Cunningham, and Paul Pearson. Field trips were led by Tobin and Keegan Brown, Jacob Cooper and UNK ornithology students, Joel Jorgensen and Stephen Brenner, T. J. Walker, and Thane Dinsdale. Destinations included various sites around Lake McConaughy, Lake Ogallala, Cedar Point Biological Station, Sutherland Reservoir SRA, Ash Hollow State Historical Park, Crescent Lake NWR, Arthur Co and various Sandhills lakes. The total species count was …
Impacts Of Nutrient Addition And Disturbance On Coastal Dune Arthropod Communities And Trophic Interactions, Kayla Beitzel
Impacts Of Nutrient Addition And Disturbance On Coastal Dune Arthropod Communities And Trophic Interactions, Kayla Beitzel
Graduate Theses and Dissertations (2019 - present)
Coastal dune ecosystems face ongoing threats from human-mediated disturbance and altered resource availability. Because these dunes provide critical habitat for many organisms, including shorebirds, beach mice, and arthropods, changes in disturbance regimes or resource availability can impact plant communities and higher trophic levels by altering plant richness and productivity, which in turn influence arthropod abundance and diversity. To examine how disturbance and nutrient addition affect arthropod communities, we established twenty 5×5 m plots on Dauphin Island, crossing mechanical disturbance with a 10 g m⁻² addition of nitrogen, phosphorus, and potassium, replicated across five experimental blocks. Arthropods were sampled using three …
Plant Community Responses To Wildfire, Timber Thinning, And Bison Reintroduction On The Northern Great Plains, Ethan H. Van-Derpoel
Plant Community Responses To Wildfire, Timber Thinning, And Bison Reintroduction On The Northern Great Plains, Ethan H. Van-Derpoel
All Theses
The Northern Great Plains (NGP) is one of the largest intact grasslands remaining in the world. These two studies examine a few of the ecological concerns on the NGP today. First, the woody encroachment of conifers into grasslands and the effects of wildfires. Second, the effects of bison (Bison bison) reintroduction on plant communities. In Chapter 1, this study aims to examine the effects of wildfire and mechanical timber thinning, using a two-by-two factorial design, on plant community responses and forage quality in the Bull Mountains area of central Montana, USA. We found that our treatments had varying …
Exploring Life History Trade-Offs In The Facultative Eusocial Bee Megalopta Genalis, Ana Gutiérrez Zuluaga
Exploring Life History Trade-Offs In The Facultative Eusocial Bee Megalopta Genalis, Ana Gutiérrez Zuluaga
All Graduate Theses and Dissertations, Fall 2023 to Present
Organisms face many trade-offs in how to invest in these traits. One example is the trade-off between reproduction and longevity. Queens of social insects seem to escape this trade-off, producing thousands of eggs daily, despite having a longer lifespan than their workers. Some hypotheses have been proposed to explain this phenomenon, such as an evolutionary change in the molecular pathways that regulate queen investment in maintenance, growth, and reproduction. An alternative hypothesis suggests that the tradeoffs are rarely observed in queens due to the extensive resources provided by the help of workers. While these hypotheses have supporting evidence, they have …
Integrating Manager Perspectives Into The Evaluation Of Wetland Revegetation Strategies, Loren F. Taylor
Integrating Manager Perspectives Into The Evaluation Of Wetland Revegetation Strategies, Loren F. Taylor
All Graduate Theses and Dissertations, Fall 2023 to Present
Ecological restoration is the process of assisting the recovery of an ecosystem that has been degraded and is dependent on complex and context-specific decisions. The decision-making process influencing restoration is rarely examined alongside ecological processes. There is a need for research that incorporates the social, economic, institutional, and logistical considerations that shape real-world practices, as well as ecological processes. Decisions made by restoration practitioners and land managers (hereon “manager”) are challenged by the lack of information shared regarding the practical constraints (e.g., cost, labor, specialized equipment) they face. Revegetation, particularly in wetlands, poses challenges due to site conditions and degradation …
Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel
Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel
Master's Theses
Distribution models provide a practical use case of connecting ecological niche theory with species’ occurrence and assemblages. By explicitly linking Hutchinson’s “niche space” with geographic space researchers can gain valuable information on a species’ niche characteristics and interactions, thereby informing conservation and management practices. The narrow-faced kangaroo rat (Dipodomys venustus) is a highly understudied kangaroo rat species endemic to the central coast of California and is an ideal species to explore niche theory in distribution modeling. Three subspecies are currently recognized: The Santa Cruz kangaroo rat (D. v. venustus), the elephant-eared kangaroo rat (D. v. …
Multiple Aspects Of Environmental Temperature Have Complex Interactions With Avian Parental Behavior To Influence Offspring Outcomes, William H. Kirkpatrick
Multiple Aspects Of Environmental Temperature Have Complex Interactions With Avian Parental Behavior To Influence Offspring Outcomes, William H. Kirkpatrick
Graduate Theses and Dissertations
Anthropogenic climate change is projected to shift not only average temperatures across the globe, but also the amount of thermal variation experienced in the natural environment. Exposure to shifts in averages and a wider range of thermal experiences will cause shifts in wildlife behavior. In avian species, behaviors exhibited during reproduction have implications for the well-being of their offspring. Here, I explore specific incubation behaviors in four species: Scaled Quail (Callipepla squamata), Northern Bobwhite Quail (Colinus virginianus), Tree Swallows (Tachycineta bicolor), and Eastern Bluebirds (Sialia sialis). I examined constancy, or the percentage of time on the nest, and off-bout duration, …
The Ecology Of Arthropod Rain In A Tropical Forest., Andrew Robert Seiler
The Ecology Of Arthropod Rain In A Tropical Forest., Andrew Robert Seiler
Electronic Theses and Dissertations
Tropical forests are structured by complex vertical linkages and nutrient exchanges between canopy and understory habitats. These linkages include the downward flux of organisms, the movement of canopy fauna, and the recycling of nutrients through litter and organic matter deposition. This dissertation investigates arthropod rain and its role in connecting the canopy and forest floor processes in a lowland tropical forest in Panama. Chapter 2 quantifies “arthropod rain”, the fall of canopy arthropods into the understory. Using pan and pole traps, I measured the composition, abundance, and biomass of arthropods falling from the canopy and assessed environmental drivers of the …
Determination Of An Effective Natural Boxelder Bug (Boisea Trivittata) Repellent, Reyna Chavez
Determination Of An Effective Natural Boxelder Bug (Boisea Trivittata) Repellent, Reyna Chavez
Theses and Dissertations
This study investigates the use of ecofriendly repellant alternatives to pest management to control boxelder bugs (Boisea trivittata). This bug gathers by the thousands on warm surfaces of exterior suburban homes during early fall and late spring. I determined bug repellency to turmeric oil (Curcuma longa), catnip (Nepeta cataria), citronella (Cymbopogon nardus), and lavender (Lavandula angustifolia). The treatments consisted of essential oils containing 20% methanol. All treatments demonstrated repellency of Boxelder bugs. Citronella was the most effective and had the highest level of repellency range of 90-99%. Catnip was the least effective with a repellency range of 63-82%.
Seagrass Preference Among Pinfish In The Lower Laguna Madre, Nathaniel Garza
Seagrass Preference Among Pinfish In The Lower Laguna Madre, Nathaniel Garza
Theses and Dissertations
Pinfish (Lagodon rhomboides) is a common estuarine fish species found from Massachusetts to the Yucatan, Mexico. As juveniles, pinfish spend a significant portion of their life in coastal seagrasses which provide both shelter from predators and food. Along the Texas coast, there are three major species of seagrass- turtle grass (Thalassia testudinum), manatee grass (Syringodium filiforme) and shoal grass (Halodule wrightii) that differ in structural complexity. The goal of this study was to determine if pinfish associate more with one seagrass species than the others. A year-long field study was completed using twelve sample sites in the Lower Laguna Madre, …
Bricks, Bushes, And Bones: Urbanization Influence On Western Fence Lizard (Sceloporus Occidentalis) Morphology And Performance, Daisy P. Xiong
Bricks, Bushes, And Bones: Urbanization Influence On Western Fence Lizard (Sceloporus Occidentalis) Morphology And Performance, Daisy P. Xiong
Electronic Theses, Projects, and Dissertations
With increasing urbanization due to rising human populations, organisms may be forced to adapt rapidly to changing environments. Urbanization is replacing natural surfaces with more impervious substrates which can result in morphological changes affecting organismal locomotion, then also impact fitness. This study compares urban and natural habitat impact on Western Fence Lizards (Sceloporus occidentalis) and their adaptations in such settings. We captured lizards from three locations in inland Southern California with both urbanized and natural habitats in order to compare the morphological differences between lizards, and then measured their performance to determine the possible impacts from their morphology. …
Golden Eagle Predation Of Greater Sage-Grouse On Diamond Mountain Plateau, Victoria E. Thorpe
Golden Eagle Predation Of Greater Sage-Grouse On Diamond Mountain Plateau, Victoria E. Thorpe
All Graduate Theses and Dissertations, Fall 2023 to Present
Predation and the perceived risk of predation can have major impacts on prey populations. Golden Eagles are considered one of the main predators of adult greater sage-grouse. Sage-grouse populations have been declining for decades throughout the West and wildlife managers are concerned about the impacts of golden eagles on sage-grouse. We investigated the nonconsumptive effects of golden eagles on sage-grouse by conducting observational surveys for golden eagles, sage-grouse, and other predators at sage-grouse lek sites near Vernal, Utah during the sage-grouse breeding season from 2022–2024. Additionally, we examined the prevalence of sage-grouse in golden eagle diet using DNA metabarcoding of …
Taxonomy Of Endophytic Fungi Associated With Vallisneria Neotropicalis, Md. Arafat Rashid
Taxonomy Of Endophytic Fungi Associated With Vallisneria Neotropicalis, Md. Arafat Rashid
Graduate Theses and Dissertations (2019 - present)
This study presents the first comprehensive taxonomic and ecological investigation of endophytic fungi (EF) associated with the submerged aquatic macrophyte Vallisneria neotropicalis in the southern United States. Over a 12 month period, from April 2023 to March 2024, leaf samples were collected from two distinct sites in Mobile Bay, Alabama a disturbed, brackish Causeway location and a cleaner, less impacted site at Meaher State Park. Using culture dependent methods, a total of 257 fungal endophytes were isolated from 1,200 leaf segments. All isolates belonged to the phylum Ascomycota, distributed across 3 classes, 6 orders, 10 families, and 19 taxa. The …
Effects Of Urbanization On The Population Genetics And Morphology Of The White-Footed Mouse (Peromyscus Leucopus) Across An Urban–Rural Gradient, Sydney A. Morton
Effects Of Urbanization On The Population Genetics And Morphology Of The White-Footed Mouse (Peromyscus Leucopus) Across An Urban–Rural Gradient, Sydney A. Morton
Master's Theses
Urbanization alters landscapes in ways that can reshape wildlife populations by changing habitat connectivity, resource availability, and selective pressures. To investigate how urbanization influences both genetic differentiation and morphology in small mammals, I examined Peromyscus leucopus (PELE) across an urban–rural gradient in northern Georgia. Using RADseq SNP data from PELE individuals across 13 sites, I quantified pairwise genetic differentiation (FST) and tested how various environmental variables, including impervious surface cover, human population density, and tree canopy cover, predict genetic differentiation after accounting for geographic distance. Genetic differentiation increased with geographic distance and, after controlling for isolation by …
Drivers Of Faunal Communities In Isolated Wetlands: Local And Landscape Determinants Of Assemblages, Joshua Holbrook
Drivers Of Faunal Communities In Isolated Wetlands: Local And Landscape Determinants Of Assemblages, Joshua Holbrook
All Dissertations
Ecological interactions such as predation are vital to shaping the distribution of organisms. For interactions to occur, organisms must undertake movement, such as dispersal, that places them in proximity to the organisms with which they may interact. Geographically isolated wetlands (GIW) are productive and biodiverse ecosystems, but little is known on broad geographic scales about the determinants of their fauna. Fishes have difficulty colonizing GIW, whereas amphibians and macroinvertebrates are adept overland dispersers – though they may be sensitive to top-down control by fishes. To better understand these phenomena, I sampled 10-20 wetlands each at nine regions in North and …
Shifting Grounds: Knowledge, Power, And Place In Changing Western Rangelands, Molly C. Levy
Shifting Grounds: Knowledge, Power, And Place In Changing Western Rangelands, Molly C. Levy
Boise State University Theses and Dissertations
Public rangelands in the American West are sites of enduring contestation, where ecological change, competing values, and institutional complexity converge. Long-standing debates over livestock grazing, wildlife conservation, and land stewardship highlight fundamental questions of whose knowledge counts, whose authority is legitimate, and how resource use should adapt under shifting social and ecological conditions. This dissertation examines the intersections of knowledge, power, and land use in collaborative governance of contested landscapes. Using the Thunder Basin ecoregion (TBER) in northeastern Wyoming as a case study, I adopt a mixed-methods approach that integrates qualitative interviews, participant observation, archival research, and quantitative analysis of …
Immunological Surveillance Against Cancer Across Mammals, Orsolya Vincze, Piotr Minias, Alexandre Corthay, Fernando Colchero, Jean-François Lemaître, Louise Maille, Tamás Malkócs, Justus Hagemann, Dalia A. Conde, Samuel Pavard, Antoine M. Dujon, Beata Ujvari, Frédéric Thomas, Amy M. Boddy, Carlo C. Maley, Damien Chevallier, Tuul Sepp, Thomas Pradeu, Mathieu Giraudeau
Immunological Surveillance Against Cancer Across Mammals, Orsolya Vincze, Piotr Minias, Alexandre Corthay, Fernando Colchero, Jean-François Lemaître, Louise Maille, Tamás Malkócs, Justus Hagemann, Dalia A. Conde, Samuel Pavard, Antoine M. Dujon, Beata Ujvari, Frédéric Thomas, Amy M. Boddy, Carlo C. Maley, Damien Chevallier, Tuul Sepp, Thomas Pradeu, Mathieu Giraudeau
Presidential Fellows Articles and Research
Contrary to expectations based on their higher cell numbers, larger and longer-lived species do not face dramatically increased risk of cancer. This strongly suggests that evolution has fashioned natural cancer resistance mechanisms, yet our knowledge remains limited on what these mechanisms might be. The cancer immunological surveillance hypothesis, proposed by Burnet and Thomas in the 1950s, highlights immunity as a key factor determining species-specific cancer resistance. Here we address the original, evolutionary interpretation of this hypothesis by investigating the relationship between cancer mortality risk and markers of efficient antigen presentation. Our results show that the expansion of the MHC class …